Homo sapiens

4 known processes

ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

(Aliases: DKFZp686N06184,FLJ10517,ASP,MCPH5,FLJ10549,FLJ43117,Calmbp1)

ASPM biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome segregationGO:00070591140.650
ribonucleotide catabolic processGO:00092614050.639
sister chromatid segregationGO:0000819540.618
nuclear divisionGO:00002801280.600
Mouse Worm
regulation of cell cycleGO:00517263930.598
ribonucleoside monophosphate catabolic processGO:00091581580.518
purine ribonucleotide catabolic processGO:00091544040.492
sister chromatid biorientationGO:003113420.468
mitotic cell cycleGO:00002783260.438
Fly
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.413
meiotic chromosome segregationGO:004513240.405
mitotic sister chromatid segregationGO:0000070530.396
mitotic cell cycle processGO:19030472860.387
Fly
ribonucleoside triphosphate catabolic processGO:00092033910.373
nucleoside monophosphate catabolic processGO:00091251590.355
cell divisionGO:00513011680.348
Mouse Fly
nucleoside triphosphate metabolic processGO:00091414220.335
cellular macromolecular complex assemblyGO:00346223240.307
Fly
maintenance of location in cellGO:0051651620.299
Mouse
spindle assembly involved in mitosisGO:0090307120.290
nucleoside phosphate catabolic processGO:19012924120.262
mitotic nuclear divisionGO:00070671190.260
microtubule anchoringGO:0034453240.255
microtubule based processGO:00070172100.233
Mouse Worm Fly
regulation of cell cycle processGO:00105642660.221
organelle fissionGO:00482851490.208
Mouse Worm
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.204
glycosyl compound catabolic processGO:19016584130.199
maintenance of protein locationGO:0045185570.191
purine ribonucleoside monophosphate catabolic processGO:00091691580.190
spindle elongationGO:005123140.185
atp catabolic processGO:00062001570.184
nucleoside triphosphate catabolic processGO:00091433940.183
maintenance of locationGO:00512351120.183
Mouse
maintenance of protein location in cellGO:0032507560.167
microtubule cytoskeleton organizationGO:00002261760.165
Mouse Worm Fly
regulation of cell divisionGO:00513021160.164
Mouse
ribonucleoside catabolic processGO:00424544060.163
ribonucleoside triphosphate metabolic processGO:00091994120.155
ribonucleoside monophosphate metabolic processGO:00091611870.155
purine ribonucleoside catabolic processGO:00461303980.148
nucleoside monophosphate metabolic processGO:00091231910.139
regulation of chromosome segregationGO:0051983440.138
purine nucleoside monophosphate metabolic processGO:00091261860.137
regulation of mitotic sister chromatid segregationGO:0033047270.133
nucleotide catabolic processGO:00091664080.133
regulation of sister chromatid segregationGO:0033045270.130
purine nucleoside triphosphate metabolic processGO:00091444120.129
purine nucleotide catabolic processGO:00061954050.124
regulation of microtubule based processGO:0032886740.124
organophosphate catabolic processGO:00464344300.122
negative regulation of cellular component organizationGO:00511292350.120
purine ribonucleoside triphosphate metabolic processGO:00092054110.119
mitotic spindle elongationGO:000002240.118
attachment of spindle microtubules to kinetochoreGO:0008608170.117
purine ribonucleoside triphosphate catabolic processGO:00092073910.115
purine nucleoside catabolic processGO:00061523980.112
organelle assemblyGO:00709251760.110
Mouse
dna conformation changeGO:00711031130.105
regulation of mitotic cell cycleGO:00073461890.104
cytokinesisGO:0000910960.104
single organism cellular localizationGO:19025803320.103
Worm Fly
stem cell divisionGO:001714520.103
Mouse Fly
microtubule based movementGO:0007018320.099
nucleoside catabolic processGO:00091644080.097
purine ribonucleoside metabolic processGO:00461284370.096
post embryonic developmentGO:000979120.094
Worm
microtubule cytoskeleton organization involved in mitosisGO:1902850150.088
cellular protein complex assemblyGO:00436231880.087
Fly
spindle assemblyGO:0051225290.082
Mouse
atp metabolic processGO:00460341760.080
negative regulation of cell cycleGO:00457861930.077
ubiquitin dependent protein catabolic processGO:00065112060.076
purine nucleoside triphosphate catabolic processGO:00091463920.074
metaphase plate congressionGO:0051310180.074
positive regulation of cell cycleGO:00457871400.074
regulation of cytoskeleton organizationGO:00514931770.071
nucleus localizationGO:005164710.069
Fly
positive regulation of protein kinase activityGO:00458601900.069
dna packagingGO:0006323770.068
positive regulation of protein phosphorylationGO:00019343130.068
positive regulation of catabolic processGO:00098963100.067
mitotic spindle midzone assemblyGO:005125640.066
cellular component disassemblyGO:0022411920.066
regulation of protein localizationGO:00328802960.065
Worm
mitotic spindle organizationGO:0007052270.059
Fly
regulation of transferase activityGO:00513383550.058
meiotic nuclear divisionGO:0007126100.058
Mouse Worm
negative regulation of organelle organizationGO:00106391260.055
blastocyst developmentGO:000182430.054
protein depolymerizationGO:0051261300.053
positive regulation of proteolysisGO:00458621420.053
regulation of kinase activityGO:00435493140.053
neuroblast divisionGO:005505710.053
Mouse
cytoskeleton dependent cytokinesisGO:0061640220.052
purine containing compound catabolic processGO:00725234110.051
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.051
embryo developmentGO:00097901230.050
Worm
posttranscriptional regulation of gene expressionGO:00106082130.049
cellular macromolecule catabolic processGO:00442653800.049
kinetochore organizationGO:005138380.048
Fly
protein maturationGO:00516042330.048
positive regulation of organelle organizationGO:00106381950.048
spindle organizationGO:0007051530.046
Mouse Worm Fly
spindle checkpointGO:0031577260.046
embryonic epithelial tube formationGO:000183840.045
positive regulation of phosphorylationGO:00423273940.043
purine nucleoside monophosphate catabolic processGO:00091281580.043
negative regulation of proteolysisGO:00458611320.042
purine ribonucleoside monophosphate metabolic processGO:00091671860.042
positive regulation of cell cycle processGO:00900681060.041
proteolysis involved in cellular protein catabolic processGO:00516032440.040
positive regulation of cellular catabolic processGO:00313312840.040
positive regulation of protein transportGO:00512221350.037
regulation of cellular component biogenesisGO:00440872810.036
somatic stem cell divisionGO:004810310.036
Mouse
positive regulation of kinase activityGO:00336742040.036
spindle midzone assemblyGO:005125540.036
establishment of organelle localizationGO:0051656590.036
Worm Fly
cell cycle phase transitionGO:00447701730.035
protein catabolic processGO:00301633250.034
intracellular protein transportGO:00068862700.034
cytoplasmic transportGO:00164823790.033
male meiosisGO:000714010.033
cellular pigmentationGO:0033059170.033
nuclear migrationGO:000709710.033
Fly
epithelium developmentGO:00604292270.032
positive regulation of apoptotic processGO:00430652460.031
chromosome separationGO:0051304230.031
protein processingGO:00164852260.030
regulation of mitotic recombinationGO:000001910.030
regulation of protein processingGO:00706131500.030
regulation of nucleocytoplasmic transportGO:0046822980.030
regulation of protein catabolic processGO:00421761550.030
positive regulation of cellular component organizationGO:00511303760.030
regulation of cell cycle phase transitionGO:19019871260.030
protein targetingGO:00066051870.029
protein targeting to nucleusGO:00447441040.029
metaphase anaphase transition of mitotic cell cycleGO:0007091210.029
vesicle mediated transportGO:00161923710.029
positive regulation of programmed cell deathGO:00430682490.029
regulation of proteolysisGO:00301622930.028
regulation of protein complex assemblyGO:00432541470.028
ras protein signal transductionGO:0007265730.028
regulation of establishment of protein localizationGO:00702012420.028
negative regulation of mitotic cell cycle phase transitionGO:1901991850.028
positive regulation of cell divisionGO:0051781590.028
regulation of mitotic cell cycle phase transitionGO:19019901180.027
regulation of microtubule cytoskeleton organizationGO:0070507610.027
establishment of nucleus localizationGO:004002310.027
Fly
positive regulation of mitosisGO:0045840250.027
modification dependent protein catabolic processGO:00199412090.027
neurogenesisGO:00220081690.027
Mouse
modification dependent macromolecule catabolic processGO:00436322120.026
embryo development ending in birth or egg hatchingGO:0009792340.026
Worm
protein importGO:00170381300.025
small gtpase mediated signal transductionGO:0007264780.025
regulation of endopeptidase activityGO:00525481700.025
regenerationGO:003109940.025
negative regulation of protein metabolic processGO:00512483910.025
protein polyubiquitinationGO:00002091100.025
regulation of cytokinesisGO:0032465450.024
regulation of cell differentiationGO:00455953930.024
Mouse
regulation of cellular response to stressGO:00801352440.024
protein localization to organelleGO:00333652800.024
anatomical structure homeostasisGO:00602491000.023
positive regulation of cytokinesisGO:0032467290.023
cell fate determinationGO:000170930.023
positive regulation of mitotic cell cycleGO:0045931600.023
somatic muscle developmentGO:000752510.023
regulation of dna metabolic processGO:00510521530.023
regulation of mitosisGO:0007088630.022
positive regulation of transportGO:00510503360.022
negative regulation of protein complex disassemblyGO:0043242200.022
neuroblast proliferationGO:000740540.022
Mouse
dephosphorylationGO:00163112090.022
meiosis iGO:000712740.022
organelle localizationGO:0051640840.022
Mouse Worm Fly
proteasomal protein catabolic processGO:00104981760.021
regulation of cytoplasmic transportGO:19036491490.021
protein import into nucleusGO:00066061040.021
positive regulation of hydrolase activityGO:00513453310.021
regulation of cellular amine metabolic processGO:0033238110.021
regulation of cellular amino acid metabolic processGO:000652160.020
chromatin modificationGO:00165682980.020
protein modification by small protein conjugationGO:00324463420.020
negative regulation of integrin activationGO:003362420.020
mitotic cell cycle checkpointGO:0007093680.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.020
negative regulation of mitotic cell cycleGO:00459301020.020
cellular amino acid metabolic processGO:00065201160.020
regulation of cell migrationGO:00303342890.020
cellular protein catabolic processGO:00442572610.020
regulation of protein kinase activityGO:00458592890.020
microtubule bundle formationGO:0001578150.019
sex determinationGO:000753030.019
mitotic cell cycle phase transitionGO:00447721620.019
tissue regenerationGO:004224630.019
protein ubiquitinationGO:00165673140.019
wnt signaling pathwayGO:00160551560.019
Mouse
negative regulation of protein maturationGO:19033181420.019
regulation of protein maturationGO:19033171500.019
negative regulation of cellular catabolic processGO:0031330830.019
negative regulation of protein catabolic processGO:0042177590.018
mitotic cytokinesisGO:0000281190.018
reproductionGO:0000003630.018
Mouse Worm Fly
regulation of locomotionGO:00400123290.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
Fly
regulation of proteasomal protein catabolic processGO:0061136870.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
nucleocytoplasmic transportGO:00069131760.018
protein dephosphorylationGO:0006470810.018
centrosome organizationGO:0051297580.018
Fly
regulation of cellular ketone metabolic processGO:0010565500.017
regulation of cell morphogenesisGO:00226041530.017
chromosome condensationGO:0030261150.017
regulation of bindingGO:00510981110.017
regulation of protein import into nucleusGO:0042306780.017
cytidine deaminationGO:000997270.017
regulation of nuclear divisionGO:0051783650.017
regulation of protein transportGO:00512232130.017
cellular response to dna damage stimulusGO:00069743790.017
mitotic metaphase plate congressionGO:0007080140.017
negative regulation of protein processingGO:00109551420.017
cellular component morphogenesisGO:00329893140.017
establishment of protein localization to organelleGO:00725941720.017
nervous system developmentGO:00073992930.017
Mouse Fly
chromatin organizationGO:00063253510.017
response to abiotic stimulusGO:00096283360.017
immune system developmentGO:00025201950.017
response to radiationGO:00093141510.016
positive regulation of nucleotide metabolic processGO:00459812300.016
primary neural tube formationGO:001402030.016
actin filament based processGO:00300292240.016
Fly
establishment of chromosome localizationGO:0051303200.016
positive regulation of cytoskeleton organizationGO:0051495830.016
negative regulation of cellular protein metabolic processGO:00322693530.016
protein complex disassemblyGO:0043241520.016
regulation of viral processGO:00507921030.016
regulation of cellular component movementGO:00512703340.016
negative regulation of mitotic sister chromatid separationGO:2000816170.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
positive regulation of nuclear divisionGO:0051785270.016
regulation of microtubule polymerization or depolymerizationGO:0031110270.016
cellular amine metabolic processGO:0044106410.016
oogenesisGO:004847720.015
Mouse Fly
cellular protein complex disassemblyGO:0043624360.015
positive regulation of intracellular transportGO:00323881040.015
negative regulation of cell cycle phase transitionGO:1901988890.015
multi organism metabolic processGO:0044033410.015
regulation of intracellular protein transportGO:00331571230.015
positive regulation of cell deathGO:00109422630.015
negative regulation of cell divisionGO:0051782310.015
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.015
asymmetric neuroblast divisionGO:005505910.015
reproductive processGO:00224141060.015
Mouse Worm Fly
regulation of response to dna damage stimulusGO:2001020940.015
receptor mediated endocytosisGO:0006898840.015
mitotic sister chromatid separationGO:0051306180.015
regulation of mitotic sister chromatid separationGO:0010965270.015
peptidyl tyrosine modificationGO:00182121700.015
positive regulation of attachment of spindle microtubules to kinetochoreGO:005198720.015
hemopoiesisGO:00300971800.015
receptor metabolic processGO:0043112810.014
endomembrane system organizationGO:00102561960.014
mitotic spindle checkpointGO:0071174180.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.014
endosomal transportGO:00161971290.014
regulation of wnt signaling pathwayGO:00301111230.014
Mouse
regulation of meiosisGO:004002030.014
positive regulation of chromosome organizationGO:2001252410.014
biological adhesionGO:00226103310.014
growthGO:00400072020.014
Mouse
macromolecular complex disassemblyGO:0032984600.014
endocytosisGO:00068971590.014
positive regulation of nucleotide catabolic processGO:00308131850.014
cytokinesis completion of separationGO:000710930.014
regulation of cellular protein catabolic processGO:1903362960.014
regulation of dephosphorylationGO:0035303960.013
regulation of protein stabilityGO:0031647870.013
regulation of protein serine threonine kinase activityGO:00719001790.013
regulation of protein dephosphorylationGO:0035304180.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
cellular ketone metabolic processGO:0042180800.013
regulation of purine nucleotide catabolic processGO:00331212050.013
regulation of mitotic metaphase anaphase transitionGO:0030071260.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.013
cell morphogenesisGO:00009022960.013
nuclear importGO:00511701060.013
regulation of peptidase activityGO:00525471800.013
cytokinetic processGO:0032506120.013
neural tube closureGO:000184330.013
cardiovascular system developmentGO:00723582620.013
regulation of cell motilityGO:20001452990.012
reciprocal meiotic recombinationGO:000713140.012
peptidyl serine modificationGO:00182091060.012
neuronal stem cell divisionGO:003644510.012
Mouse
negative regulation of programmed cell deathGO:00430693210.012
regulation of intracellular transportGO:00323861950.012
regulation of mapk cascadeGO:00434082620.012
negative regulation of wnt signaling pathwayGO:0030178690.012
negative regulation of catabolic processGO:00098951040.012
gtp catabolic processGO:00061842370.012
regulation of chromosome organizationGO:00330441030.012
positive regulation of protein catabolic processGO:0045732750.012
centrosome separationGO:005129930.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
positive regulation of peptidase activityGO:0010952880.011
protein localization to nucleusGO:00345041360.011
negative regulation of catalytic activityGO:00430863350.011
negative regulation of cell cycle processGO:00109481210.011
cdc42 protein signal transductionGO:003248840.011
protein autophosphorylationGO:00467771230.011
multi organism cellular processGO:00447641560.011
actin cytoskeleton organizationGO:00300362070.011
Fly
single organism membrane organizationGO:00448022680.011
single organism reproductive processGO:0044702980.011
Mouse Worm Fly
response to oxygen containing compoundGO:19017003690.011
regulation of gtpase activityGO:00430871800.011
negative regulation of chromosome organizationGO:2001251480.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
viral genome replicationGO:0019079500.011
positive regulation of intracellular protein transportGO:0090316760.011
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.011
ribosome assemblyGO:004225590.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
positive regulation of cytoplasmic transportGO:1903651820.011
negative regulation of cellular protein catabolic processGO:1903363380.011
positive regulation of transferase activityGO:00513472270.011
vesicle organizationGO:0016050620.011
dna recombinationGO:0006310770.010
negative regulation of dna templated transcription initiationGO:200014330.010
positive regulation of wnt signaling pathwayGO:0030177540.010
Mouse
negative regulation of sister chromatid segregationGO:0033046170.010
mitotic chromosome condensationGO:0007076110.010
response to oxidative stressGO:00069791210.010
regulation of purine nucleotide metabolic processGO:19005422640.010
regulation of nucleotide metabolic processGO:00061402690.010
morphogenesis of embryonic epitheliumGO:001633140.010
regulation of meiotic cell cycleGO:005144540.010
immune responseGO:00069553070.010

ASPM disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.021
physical disorderDOID:0080015410.007
congenital nervous system abnormalityDOID:2490210.007
microcephalyDOID:1090760.002