Homo sapiens

38 known processes

SERGEF

secretion regulating guanine nucleotide exchange factor

(Aliases: DELGEF,Gnefr)

SERGEF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523150.097
chromatin organizationGO:00063253510.073
positive regulation of cellular component organizationGO:00511303760.063
histone modificationGO:00165702510.057
protein modification by small protein conjugationGO:00324463420.054
covalent chromatin modificationGO:00165692540.053
cellular response to dna damage stimulusGO:00069743790.052
membrane organizationGO:00610242920.049
regulation of cell cycleGO:00517263930.048
cellular macromolecule catabolic processGO:00442653800.048
immune responseGO:00069553070.045
positive regulation of transportGO:00510503360.042
protein catabolic processGO:00301633250.040
single organism cellular localizationGO:19025803320.039
lipid metabolic processGO:00066293810.039
cellular lipid metabolic processGO:00442553030.039
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.039
positive regulation of programmed cell deathGO:00430682490.038
cytoplasmic transportGO:00164823790.038
mitotic cell cycle processGO:19030472860.038
nucleoside triphosphate catabolic processGO:00091433940.038
neuromuscular junction developmentGO:000752830.037
endomembrane system organizationGO:00102561960.037
organophosphate catabolic processGO:00464344300.036
regulation of cellular amine metabolic processGO:0033238110.035
monocarboxylic acid metabolic processGO:00327871850.035
small gtpase mediated signal transductionGO:0007264780.034
negative regulation of catalytic activityGO:00430863350.034
carbohydrate metabolic processGO:00059752070.034
oxidation reduction processGO:00551143960.034
locomotory behaviorGO:000762610.034
oogenesisGO:004847720.033
negative regulation of cellular protein metabolic processGO:00322693530.033
protein localization to membraneGO:00726571600.033
post embryonic developmentGO:000979120.033
negative regulation of cell deathGO:00605483450.033
ribonucleoside triphosphate metabolic processGO:00091994120.032
vesicle mediated transportGO:00161923710.032
establishment of protein localization to membraneGO:00901501210.032
protein ubiquitinationGO:00165673140.032
purine nucleotide catabolic processGO:00061954050.032
cellular protein catabolic processGO:00442572610.031
regulation of cell cycle processGO:00105642660.031
response to external biotic stimulusGO:00432072610.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
ribonucleoside triphosphate catabolic processGO:00092033910.031
chromatin modificationGO:00165682980.031
single organism membrane organizationGO:00448022680.030
nucleotide catabolic processGO:00091664080.030
purine nucleoside catabolic processGO:00061523980.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
innate immune responseGO:00450871780.030
negative regulation of programmed cell deathGO:00430693210.030
cellular amine metabolic processGO:0044106410.029
purine ribonucleotide catabolic processGO:00091544040.029
nucleoside triphosphate metabolic processGO:00091414220.029
purine ribonucleoside metabolic processGO:00461284370.029
nucleoside catabolic processGO:00091644080.029
plasma membrane organizationGO:00070091150.029
response to abiotic stimulusGO:00096283360.029
positive regulation of cell deathGO:00109422630.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
cellular ketone metabolic processGO:0042180800.028
regulation of transferase activityGO:00513383550.028
single organism carbohydrate metabolic processGO:00447231930.028
response to oxygen containing compoundGO:19017003690.027
ubiquitin dependent protein catabolic processGO:00065112060.027
determination of adult lifespanGO:000834020.027
positive regulation of cell proliferationGO:00082843010.027
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.027
modification dependent protein catabolic processGO:00199412090.026
nucleoside phosphate catabolic processGO:19012924120.026
female gamete generationGO:000729220.026
nervous system developmentGO:00073992930.026
secretionGO:00469032540.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
chemical homeostasisGO:00488783060.025
regulation of protein localizationGO:00328802960.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
intracellular protein transportGO:00068862700.025
mitotic cell cycleGO:00002783260.025
positive regulation of organelle organizationGO:00106381950.025
regulation of cellular ketone metabolic processGO:0010565500.025
metal ion transportGO:00300012720.024
regulation of proteolysisGO:00301622930.024
cellular amino acid metabolic processGO:00065201160.024
negative regulation of protein modification processGO:00314002000.024
biological adhesionGO:00226103310.023
regulation of purine nucleotide metabolic processGO:19005422640.023
amine metabolic processGO:0009308440.023
regulation of intracellular transportGO:00323861950.023
regulation of defense responseGO:00313471540.023
positive regulation of immune system processGO:00026842830.023
protein localization to organelleGO:00333652800.023
protein localization to plasma membraneGO:0072659930.023
purine ribonucleoside catabolic processGO:00461303980.023
positive regulation of apoptotic processGO:00430652460.023
microtubule based processGO:00070172100.022
Yeast
ribonucleoside catabolic processGO:00424544060.022
purine containing compound catabolic processGO:00725234110.022
protein processingGO:00164852260.022
regulation of protein kinase activityGO:00458592890.022
positive regulation of hormone biosynthetic processGO:004688640.022
response to biotic stimulusGO:00096072760.022
segmentationGO:003528240.022
post golgi vesicle mediated transportGO:0006892360.021
protein maturationGO:00516042330.021
dna repairGO:00062811980.021
positive regulation of hydrolase activityGO:00513453310.021
regulation of vesicle mediated transportGO:00606271300.021
epidermis morphogenesisGO:004873030.021
negative regulation of phosphate metabolic processGO:00459362670.021
endosomal transportGO:00161971290.021
ribonucleotide catabolic processGO:00092614050.021
golgi vesicle transportGO:0048193800.021
small molecule biosynthetic processGO:00442831570.021
gtp catabolic processGO:00061842370.021
regulation of secretionGO:00510461940.020
negative regulation of multicellular organismal processGO:00512413170.020
regulation of cellular component movementGO:00512703340.020
positive regulation of cellular amine metabolic processGO:003324070.020
proteasomal protein catabolic processGO:00104981760.020
regulation of mitotic cell cycleGO:00073461890.020
establishment of protein localization to organelleGO:00725941720.020
guanosine containing compound metabolic processGO:19010682440.020
actin filament based processGO:00300292240.020
secretion by cellGO:00329402260.020
vesicle organizationGO:0016050620.020
fatty acid metabolic processGO:00066311150.020
regulation of purine nucleotide catabolic processGO:00331212050.020
negative regulation of cell proliferationGO:00082852280.020
cellular macromolecular complex assemblyGO:00346223240.020
gtp metabolic processGO:00460392390.020
response to radiationGO:00093141510.019
regulation of cellular amino acid metabolic processGO:000652160.019
negative regulation of protein metabolic processGO:00512483910.019
ras protein signal transductionGO:0007265730.019
rhythmic behaviorGO:000762220.019
maintenance of locationGO:00512351120.019
response to other organismGO:00517072610.019
negative regulation of intracellular signal transductionGO:19025321830.019
interspecies interaction between organismsGO:00444191560.019
negative regulation of protein maturationGO:19033181420.019
multicellular organismal agingGO:001025930.019
regulation of kinase activityGO:00435493140.019
positive regulation of synaptic transmissionGO:005080640.019
regulation of cell migrationGO:00303342890.019
regulation of synaptic plasticityGO:004816730.019
transmembrane transportGO:00550853990.019
lipid biosynthetic processGO:00086101770.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
regulation of nucleotide catabolic processGO:00308112050.019
regulation of cytokine productionGO:00018172320.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
cellular response to endogenous stimulusGO:00714953360.019
regulation of transcription during mitosisGO:004589620.019
regulation of protein ubiquitinationGO:0031396950.019
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.019
glycosyl compound catabolic processGO:19016584130.019
regulation of cell motilityGO:20001452990.018
regulation of endopeptidase activityGO:00525481700.018
regulation of locomotionGO:00400123290.018
memoryGO:000761330.018
cytokine productionGO:00018162470.018
establishment of protein localization to plasma membraneGO:0090002680.018
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.018
carbohydrate derivative biosynthetic processGO:19011372070.018
regulation of gtp catabolic processGO:00331241800.018
guanosine containing compound catabolic processGO:19010692390.018
system processGO:00030083490.018
cellular response to oxygen containing compoundGO:19017012760.018
carboxylic acid biosynthetic processGO:0046394970.018
posttranscriptional regulation of gene expressionGO:00106082130.018
positive regulation of protein ubiquitinationGO:0031398530.018
regulation of cell differentiationGO:00455953930.018
inner ear morphogenesisGO:004247240.018
defense response to fungusGO:005083240.018
cation transportGO:00068123310.018
cell growthGO:00160491600.018
mitotic cell cycle phase transitionGO:00447721620.018
negative regulation of phosphorylationGO:00423261740.018
negative regulation of protein processingGO:00109551420.017
regulation of axon guidanceGO:190266730.017
regulation of nucleotide metabolic processGO:00061402690.017
regulation of response to external stimulusGO:00321012220.017
negative regulation of cell cycleGO:00457861930.017
regulation of cellular response to stressGO:00801352440.017
blastoderm segmentationGO:000735020.017
i kappab kinase nf kappab signalingGO:00072491660.017
release of cytoplasmic sequestered nf kappabGO:000858840.017
modification dependent macromolecule catabolic processGO:00436322120.017
negative regulation of phosphorus metabolic processGO:00105632670.017
multi organism cellular processGO:00447641560.017
wnt signaling pathwayGO:00160551560.017
regulation of protein modification by small protein conjugation or removalGO:19033201070.017
cell divisionGO:00513011680.017
Yeast
regulation of neural precursor cell proliferationGO:200017740.017
positive regulation of interleukin 5 productionGO:003275430.017
negative regulation of proteolysisGO:00458611320.017
positive regulation of phosphorylationGO:00423273940.017
regulation of gtpase activityGO:00430871800.017
methylationGO:00322591060.017
limbic system developmentGO:002176130.017
negative regulation of cellular component organizationGO:00511292350.017
regulation of immune responseGO:00507762010.017
regulation of cell cycle phase transitionGO:19019871260.016
positive regulation of catabolic processGO:00098963100.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
immune system developmentGO:00025201950.016
compound eye developmentGO:004874910.016
golgi vesicle fusion to target membraneGO:004821020.016
viral life cycleGO:00190581320.016
response to fungusGO:000962040.016
negative regulation of hydrolase activityGO:00513461820.016
negative regulation of developmental processGO:00510932470.016
positive regulation of intracellular transportGO:00323881040.016
cell cycle phase transitionGO:00447701730.016
somatic stem cell divisionGO:004810310.016
negative regulation of immune system processGO:00026831360.016
regulation of protein catabolic processGO:00421761550.016
oocyte developmentGO:004859910.016
regulation of secretion by cellGO:19035301770.016
regulation of establishment of protein localizationGO:00702012420.016
growthGO:00400072020.016
Yeast
protein targetingGO:00066051870.016
rho protein signal transductionGO:0007266260.016
negative regulation of cellular amine metabolic processGO:003323930.016
regulation of protein maturationGO:19033171500.016
regenerationGO:003109940.015
negative regulation of apoptotic processGO:00430663160.015
organonitrogen compound biosynthetic processGO:19015662000.015
photoreceptor cell differentiationGO:004653020.015
stem cell divisionGO:001714520.015
dna conformation changeGO:00711031130.015
positive regulation of transferase activityGO:00513472270.015
regulation of protein processingGO:00706131500.015
positive regulation of neural precursor cell proliferationGO:200017920.015
cytokinesisGO:0000910960.015
regulation of chromosome organizationGO:00330441030.015
regulation of dna metabolic processGO:00510521530.015
regulation of protein transportGO:00512232130.015
cellular component morphogenesisGO:00329893140.015
regulation of growthGO:00400081650.015
apoptotic signaling pathwayGO:00971902680.014
neurotransmitter secretionGO:000726940.014
regulation of apoptotic signaling pathwayGO:20012331750.014
metencephalon developmentGO:002203720.014
double strand break repairGO:00063021010.014
response to virusGO:00096151260.014
neurological system processGO:00508771630.014
histone methylationGO:0016571600.014
regulation of peptidase activityGO:00525471800.014
regulation of protein complex assemblyGO:00432541470.014
cellular protein complex assemblyGO:00436231880.014
ion transmembrane transportGO:00342203380.014
positive regulation of cell cycleGO:00457871400.014
glycoprotein metabolic processGO:00091001100.014
nitrogen compound transportGO:00717051910.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
positive regulation of cell motilityGO:20001471770.014
positive regulation of cellular catabolic processGO:00313312840.014
negative regulation of dna metabolic processGO:0051053570.014
positive regulation of transcription during mitosisGO:004589720.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
positive regulation of proteolysisGO:00458621420.014
peptidyl serine phosphorylationGO:00181051010.014
cellular response to lipidGO:00713961270.014
response to cytokineGO:00340972320.014
regulation of mapk cascadeGO:00434082620.014
positive regulation of secretionGO:00510471160.014
cell developmentGO:00484683280.014
hindbrain developmentGO:003090230.014
regulation of innate immune responseGO:0045088970.014
cardiac muscle cell contractionGO:008600340.014
associative learningGO:000830610.014
spermatid developmentGO:000728640.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
regulation of cellular component biogenesisGO:00440872810.014
peripheral nervous system developmentGO:000742220.014
regulation of response to dna damage stimulusGO:2001020940.013
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.013
regulation of axon extension involved in axon guidanceGO:004884120.013
lipid catabolic processGO:0016042840.013
negative regulation of kinase activityGO:00336731060.013
circadian behaviorGO:004851220.013
negative regulation of catabolic processGO:00098951040.013
response to organic cyclic compoundGO:00140702040.013
cell cycle arrestGO:0007050710.013
regulation of homeostatic processGO:00328441210.013
negative regulation of cell cycle processGO:00109481210.013
positive regulation of protein phosphorylationGO:00019343130.013
negative regulation of peptidase activityGO:0010466910.013
spermatid differentiationGO:004851540.013
protein methylationGO:0006479740.013
negative regulation of protein phosphorylationGO:00019331400.013
positive regulation of kinase activityGO:00336742040.013
positive regulation of cell differentiationGO:00455972110.013
adult locomotory behaviorGO:000834410.013
reactive oxygen species biosynthetic processGO:190340940.013
cellular response to cytokine stimulusGO:00713451810.013
negative regulation of protein transportGO:0051224750.013
small molecule catabolic processGO:0044282920.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
tripartite regional subdivisionGO:000735120.013
rna interferenceGO:001624640.013
regulation of cytoskeleton organizationGO:00514931770.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
anterior posterior axis specification embryoGO:000859520.013
regulation of cell growthGO:00015581350.013
glycoprotein biosynthetic processGO:0009101910.013
motor neuron axon guidanceGO:000804520.013
reactive oxygen species metabolic processGO:0072593750.013
positive regulation of developmental processGO:00510943140.013
regulation of neurotransmitter secretionGO:004692830.013
peptidyl serine modificationGO:00182091060.013
cerebellum developmentGO:002154920.013
morphogenesis of embryonic epitheliumGO:001633140.013
detection of stimulusGO:0051606850.013
regulation of nucleoside metabolic processGO:00091182090.013
negative regulation of transportGO:00510511760.013
startle responseGO:000196430.013
sensory perception of smellGO:000760820.013
response to lipidGO:00339932060.012
cell part morphogenesisGO:00329901370.012
glycerolipid metabolic processGO:00464861070.012
tissue regenerationGO:004224630.012
protein polyubiquitinationGO:00002091100.012
negative regulation of transferase activityGO:00513481240.012
negative regulation of endopeptidase activityGO:0010951840.012
mitotic nuclear divisionGO:00070671190.012
regulation of anatomical structure morphogenesisGO:00226032860.012
sensory perceptionGO:00076001030.012
nuclear divisionGO:00002801280.012
microtubule cytoskeleton organizationGO:00002261760.012
Yeast
immune effector processGO:00022521590.012
single organism membrane fusionGO:0044801370.012
organophosphate biosynthetic processGO:00904071630.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
regulation of cell developmentGO:00602841610.012
hemopoiesisGO:00300971800.012
macromolecule methylationGO:0043414970.012
morphogenesis of a polarized epitheliumGO:000173830.012
positive regulation of nucleoside metabolic processGO:00459791860.012
protein stabilizationGO:0050821640.012
sodium ion transportGO:0006814610.012
negative regulation of organelle organizationGO:00106391260.012
organic acid catabolic processGO:0016054710.012
positive regulation of locomotionGO:00400171860.012
protein importGO:00170381300.012
cellular lipid catabolic processGO:0044242650.012
cell morphogenesisGO:00009022960.012
anion transportGO:00068201610.012
organic hydroxy compound metabolic processGO:19016151470.012
inorganic ion transmembrane transportGO:00986602310.012
neuronal stem cell divisionGO:003644510.012
cellular carbohydrate metabolic processGO:0044262840.012
positive regulation of nucleotide metabolic processGO:00459812300.012
regulation of lipid metabolic processGO:0019216960.012
cellular response to organic cyclic compoundGO:00714071270.012
viral processGO:00160321460.012
visual behaviorGO:000763220.012
protein oligomerizationGO:00512591730.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
regulation of cell divisionGO:00513021160.011
negative regulation of protein kinase activityGO:0006469980.011
myeloid cell differentiationGO:00300991170.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
epithelial cell migrationGO:00106311190.011
oocyte differentiationGO:000999420.011
protein acylationGO:00435431380.011
golgi ribbon formationGO:009016130.011
nuclear transportGO:00511691790.011
anterior posterior axis specificationGO:000994820.011
cation transmembrane transportGO:00986552380.011
inorganic cation transmembrane transportGO:00986621940.011
neuroblast divisionGO:005505710.011
positive regulation of nucleotide catabolic processGO:00308131850.011
receptor metabolic processGO:0043112810.011
establishment of organelle localizationGO:0051656590.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
syncytium formation by plasma membrane fusionGO:000076820.011
epithelial to mesenchymal transitionGO:0001837480.011
ion homeostasisGO:00508012300.011
establishment of planar polarityGO:000173630.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
protein alkylationGO:0008213740.011
protein localization to adherens junctionGO:007189620.011
positive regulation of peptidase activityGO:0010952880.011
vitamin d receptor signaling pathwayGO:007056140.011
regulation of glial cell differentiationGO:004568530.011
response to inorganic substanceGO:00100351270.011
asymmetric neuroblast divisionGO:005505910.011
regulation of hormone levelsGO:00108171250.011
regulation of cell morphogenesisGO:00226041530.011
organelle assemblyGO:00709251760.011
ameboidal type cell migrationGO:00016671350.011
translationGO:00064121320.011
mrna metabolic processGO:00160711750.011
positive regulation of bindingGO:0051099450.011
sensory perception of painGO:001923340.011
epithelium migrationGO:00901321190.011
neurogenesisGO:00220081690.011
positive regulation of cytokine productionGO:00018191670.011
histone serine phosphorylationGO:003540440.011
mitochondrion organizationGO:00070051560.011
hippocampus developmentGO:002176610.011
regulation of leukocyte activationGO:00026941150.011
hair follicle morphogenesisGO:003106920.011
matingGO:000761810.011
nerve developmentGO:002167540.011
chromosome segregationGO:00070591140.011
lipid modificationGO:0030258840.011
neural crest cell developmentGO:001403230.011
endochondral bone morphogenesisGO:006035030.011
regulation of chromatin organizationGO:1902275560.011
protein dephosphorylationGO:0006470810.011
meiosis iGO:000712740.011
regulation of behaviorGO:0050795820.011
dna packagingGO:0006323770.010
atp metabolic processGO:00460341760.010
defense response to other organismGO:00985421290.010
proteasomal ubiquitin independent protein catabolic processGO:001049930.010
regulation of bindingGO:00510981110.010
positive regulation of immune responseGO:00507781590.010
regulation of cell cycle arrestGO:0071156360.010
mapk cascadeGO:00001652880.010
cell cycle checkpointGO:00000751170.010
protein glycosylationGO:0006486620.010
pituitary gland developmentGO:002198320.010
regulation of protein stabilityGO:0031647870.010
angiogenesisGO:00015251470.010
endothelial cell proliferationGO:0001935650.010
reactive nitrogen species metabolic processGO:200105730.010
cellular chemical homeostasisGO:00550821800.010
organic acid biosynthetic processGO:0016053970.010
glycosylationGO:0070085710.010
peptidyl lysine acetylationGO:00183941010.010
regulation of reactive oxygen species metabolic processGO:2000377410.010
actin mediated cell contractionGO:0070252120.010
exocytosisGO:0006887710.010
cell projection organizationGO:00300302520.010
rna processingGO:00063962550.010
Yeast
positive regulation of cell cycle processGO:00900681060.010
regulation of dna repairGO:0006282470.010
regulation of cytoplasmic transportGO:19036491490.010
regulation of membrane potentialGO:0042391950.010
establishment of tissue polarityGO:000716430.010
actin filament based movementGO:0030048170.010

SERGEF disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.052
inherited metabolic disorderDOID:6552420.024
central nervous system diseaseDOID:3311860.019
nervous system diseaseDOID:8634310.019
musculoskeletal system diseaseDOID:172230.018
sensory system diseaseDOID:00501552030.015
connective tissue diseaseDOID:651090.013
eye and adnexa diseaseDOID:14921500.013
disease of cellular proliferationDOID:145661740.012
cancerDOID:1621670.012
organ system cancerDOID:00506861640.012
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
immune system diseaseDOID:29141550.012
eye diseaseDOID:56141490.012
retinal diseaseDOID:56791180.012
brain diseaseDOID:936730.011
bone diseaseDOID:0080001880.011
hematopoietic system diseaseDOID:741000.010
acquired metabolic diseaseDOID:0060158580.010
carbohydrate metabolism diseaseDOID:0050013320.010
disease of mental healthDOID:150700.010