Homo sapiens

26 known processes

FLG

filaggrin

(Aliases: ATOD2)

FLG biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epidermis morphogenesisGO:004873030.139
keratinizationGO:003142420.083
copulationGO:000762010.078
matingGO:000761810.062
cellular amino acid metabolic processGO:00065201160.062
regulation of cellular amino acid metabolic processGO:000652160.058
post embryonic developmentGO:000979120.055
regulation of cellular amine metabolic processGO:0033238110.050
protein processingGO:00164852260.049
positive regulation of cellular amino acid metabolic processGO:004576430.046
cellular ketone metabolic processGO:0042180800.044
cellular amine metabolic processGO:0044106410.042
protein maturationGO:00516042330.042
ras protein signal transductionGO:0007265730.041
g protein coupled receptor signaling pathwayGO:00071862070.041
amine metabolic processGO:0009308440.039
regulation of cellular ketone metabolic processGO:0010565500.038
purine ribonucleoside metabolic processGO:00461284370.038
epithelium developmentGO:00604292270.038
ribonucleoside catabolic processGO:00424544060.038
purine containing compound catabolic processGO:00725234110.037
ion transmembrane transportGO:00342203380.037
nucleoside triphosphate metabolic processGO:00091414220.036
small gtpase mediated signal transductionGO:0007264780.036
locomotory behaviorGO:000762610.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
negative regulation of multicellular organismal processGO:00512413170.035
positive regulation of cellular amine metabolic processGO:003324070.035
hair follicle morphogenesisGO:003106920.035
nucleotide catabolic processGO:00091664080.035
inorganic ion transmembrane transportGO:00986602310.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
positive regulation of phosphorylationGO:00423273940.035
transmembrane transportGO:00550853990.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
glycosyl compound catabolic processGO:19016584130.034
organophosphate catabolic processGO:00464344300.034
purine nucleotide catabolic processGO:00061954050.034
nucleoside phosphate catabolic processGO:19012924120.033
ribonucleotide catabolic processGO:00092614050.033
multicellular organismal agingGO:001025930.033
system processGO:00030083490.032
positive regulation of transportGO:00510503360.032
chemical homeostasisGO:00488783060.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
determination of adult lifespanGO:000834020.031
positive regulation of hydrolase activityGO:00513453310.031
cation transmembrane transportGO:00986552380.031
positive regulation of catabolic processGO:00098963100.031
actin filament based processGO:00300292240.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
membrane organizationGO:00610242920.030
cardiac muscle cell contractionGO:008600340.030
skin developmentGO:0043588760.030
epithelium migrationGO:00901321190.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
female gamete generationGO:000729220.030
nucleoside triphosphate catabolic processGO:00091433940.029
purine ribonucleoside catabolic processGO:00461303980.029
negative regulation of protein metabolic processGO:00512483910.029
regulation of anatomical structure morphogenesisGO:00226032860.029
negative regulation of cellular protein metabolic processGO:00322693530.029
regulation of cell differentiationGO:00455953930.029
signal transduction by phosphorylationGO:00230142970.029
purine nucleoside catabolic processGO:00061523980.029
cytoplasmic transportGO:00164823790.028
regenerationGO:003109940.028
negative regulation of catalytic activityGO:00430863350.028
secretion by cellGO:00329402260.028
seminal clot liquefactionGO:007068410.028
negative regulation of programmed cell deathGO:00430693210.028
positive regulation of cell proliferationGO:00082843010.028
inorganic cation transmembrane transportGO:00986621940.027
single organism cellular localizationGO:19025803320.027
negative regulation of cell deathGO:00605483450.027
purine ribonucleotide catabolic processGO:00091544040.027
ion homeostasisGO:00508012300.026
lipid metabolic processGO:00066293810.026
regulation of cellular component movementGO:00512703340.026
positive regulation of cellular component organizationGO:00511303760.026
vesicle mediated transportGO:00161923710.025
biological adhesionGO:00226103310.025
Human
positive regulation of nucleotide metabolic processGO:00459812300.025
cell activationGO:00017752130.025
tissue migrationGO:00901301190.025
negative regulation of apoptotic processGO:00430663160.025
regulation of establishment of protein localizationGO:00702012420.024
cellular response to oxygen containing compoundGO:19017012760.024
cation transportGO:00068123310.024
cell developmentGO:00484683280.024
positive regulation of cellular catabolic processGO:00313312840.024
oogenesisGO:004847720.024
cellular response to dna damage stimulusGO:00069743790.024
immune responseGO:00069553070.024
inseminationGO:000732010.024
single organism membrane organizationGO:00448022680.023
regulation of protein localizationGO:00328802960.023
cell morphogenesisGO:00009022960.023
cell projection organizationGO:00300302520.023
tissue regenerationGO:004224630.023
response to abiotic stimulusGO:00096283360.023
Human
regulation of nucleoside metabolic processGO:00091182090.023
epithelial cell differentiationGO:00308551410.023
guanosine containing compound catabolic processGO:19010692390.023
organ morphogenesisGO:00098871470.023
nucleoside catabolic processGO:00091644080.023
negative regulation of cellular amine metabolic processGO:003323930.023
regulation of nucleotide metabolic processGO:00061402690.023
regulation of transferase activityGO:00513383550.023
regulation of purine nucleotide metabolic processGO:19005422640.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of proteolysisGO:00301622930.022
cellular component morphogenesisGO:00329893140.022
epidermis developmentGO:0008544590.022
regulation of cell motilityGO:20001452990.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
positive regulation of locomotionGO:00400171860.022
defense responseGO:00069523150.022
neuromuscular junction developmentGO:000752830.022
cellular response to endogenous stimulusGO:00714953360.022
intracellular protein transportGO:00068862700.022
guanosine containing compound metabolic processGO:19010682440.022
positive regulation of cell deathGO:00109422630.022
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
memoryGO:000761330.022
associative learningGO:000830610.021
mapk cascadeGO:00001652880.021
metal ion transportGO:00300012720.021
secretionGO:00469032540.021
regulation of transmission of nerve impulseGO:005196920.021
phylloquinone metabolic processGO:004237420.021
regulation of protein transportGO:00512232130.021
response to biotic stimulusGO:00096072760.021
response to organic cyclic compoundGO:00140702040.021
positive regulation of peptidyl serine phosphorylation of stat proteinGO:003314130.021
cell adhesionGO:00071553250.021
Human
regulation of nucleotide catabolic processGO:00308112050.021
regulation of locomotionGO:00400123290.021
response to fungusGO:000962040.021
single organism cell adhesionGO:00986021790.021
Human
striated muscle contractionGO:0006941520.021
regulation of secretionGO:00510461940.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
positive regulation of immune system processGO:00026842830.020
protein localization to organelleGO:00333652800.020
actin mediated cell contractionGO:0070252120.020
endomembrane system organizationGO:00102561960.020
small molecule biosynthetic processGO:00442831570.020
cellular macromolecule catabolic processGO:00442653800.020
negative regulation of phosphorus metabolic processGO:00105632670.020
cardiac muscle contractionGO:0060048340.020
response to external biotic stimulusGO:00432072610.020
positive regulation of apoptotic processGO:00430652460.020
regulation of cell cycle processGO:00105642660.020
regulation of peptidase activityGO:00525471800.019
regulation of endopeptidase activityGO:00525481700.019
response to other organismGO:00517072610.019
gtp catabolic processGO:00061842370.019
regulation of cell cycleGO:00517263930.019
regulation of kinase activityGO:00435493140.019
positive regulation of synaptic transmissionGO:005080640.019
positive regulation of cell migrationGO:00303351720.019
segmentationGO:003528240.019
oxidation reduction processGO:00551143960.019
gtp metabolic processGO:00460392390.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
positive regulation of programmed cell deathGO:00430682490.019
morphogenesis of embryonic epitheliumGO:001633140.019
actin cytoskeleton organizationGO:00300362070.019
regulation of gtpase activityGO:00430871800.019
fatty acid omega oxidationGO:001043020.019
reactive nitrogen species metabolic processGO:200105730.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of cell migrationGO:00303342890.019
positive regulation of nucleotide catabolic processGO:00308131850.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
apoptotic signaling pathwayGO:00971902680.018
growthGO:00400072020.018
ameboidal type cell migrationGO:00016671350.018
positive regulation of nucleoside metabolic processGO:00459791860.018
regulation of cellular response to stressGO:00801352440.018
regulation of cytokine productionGO:00018172320.018
innate immune responseGO:00450871780.018
maintenance of locationGO:00512351120.018
negative regulation of cell proliferationGO:00082852280.018
negative regulation of developmental processGO:00510932470.018
regulation of synaptic plasticityGO:004816730.018
tissue morphogenesisGO:0048729960.018
chromatin organizationGO:00063253510.018
positive regulation of cellular component movementGO:00512721810.018
positive regulation of protein phosphorylationGO:00019343130.018
spermatid differentiationGO:004851540.018
circulatory system developmentGO:00723592620.018
limbic system developmentGO:002176130.018
cellular lipid metabolic processGO:00442553030.018
zymogen activationGO:0031638700.018
anion transportGO:00068201610.018
hindbrain developmentGO:003090230.018
anatomical structure homeostasisGO:00602491000.018
cation homeostasisGO:00550801890.017
anterior posterior axis specificationGO:000994820.017
rho protein signal transductionGO:0007266260.017
positive regulation of developmental processGO:00510943140.017
negative regulation of phosphate metabolic processGO:00459362670.017
regulation of purine nucleotide catabolic processGO:00331212050.017
peripheral nervous system developmentGO:000742220.017
positive regulation of cell motilityGO:20001471770.017
cellular cation homeostasisGO:00300031630.017
visual behaviorGO:000763220.017
oocyte developmentGO:004859910.017
cellular response to cytokine stimulusGO:00713451810.017
regulation of cell adhesionGO:00301551660.017
regulation of protein kinase activityGO:00458592890.017
muscle system processGO:0003012810.017
posttranscriptional regulation of gene expressionGO:00106082130.017
mitotic cell cycleGO:00002783260.017
adult locomotory behaviorGO:000834410.017
forelimb morphogenesisGO:003513640.017
endothelial cell migrationGO:0043542860.017
reactive oxygen species metabolic processGO:0072593750.017
negative regulation of transportGO:00510511760.017
epithelial cell migrationGO:00106311190.017
negative regulation of protein modification processGO:00314002000.017
regulation of reactive oxygen species biosynthetic processGO:190342630.017
regulation of cell developmentGO:00602841610.017
muscle contractionGO:0006936730.017
response to oxygen containing compoundGO:19017003690.016
blood vessel morphogenesisGO:00485141620.016
regulation of actin filament based processGO:00329701410.016
oocyte differentiationGO:000999420.016
rhythmic behaviorGO:000762220.016
positive regulation of gtp catabolic processGO:00331261660.016
neurogenesisGO:00220081690.016
cellular protein catabolic processGO:00442572610.016
protein catabolic processGO:00301633250.016
nervous system developmentGO:00073992930.016
regulation of mapk cascadeGO:00434082620.016
motor neuron axon guidanceGO:000804520.016
mitotic cell cycle processGO:19030472860.016
regulation of protein maturationGO:19033171500.016
divalent inorganic cation homeostasisGO:00725071360.016
spermatid developmentGO:000728640.016
nitrogen compound transportGO:00717051910.016
embryonic forelimb morphogenesisGO:003511540.016
negative regulation of cellular component organizationGO:00511292350.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of peptidyl serine phosphorylation of stat proteinGO:003313930.016
response to lipidGO:00339932060.016
chromatin modificationGO:00165682980.016
hair cycleGO:0042633280.016
metal ion homeostasisGO:00550651690.015
negative regulation of interleukin 5 secretionGO:200066310.015
regulation of apoptotic signaling pathwayGO:20012331750.015
cellular homeostasisGO:00197251960.015
embryonic epithelial tube formationGO:000183840.015
actin filament based movementGO:0030048170.015
anterior posterior axis specification embryoGO:000859520.015
regulation of gtp catabolic processGO:00331241800.015
regulation of cellular component biogenesisGO:00440872810.015
nuclear transportGO:00511691790.015
regulation of meiotic cell cycleGO:005144540.015
sequestering of metal ionGO:0051238240.015
regulation of response to external stimulusGO:00321012220.015
cardiovascular system developmentGO:00723582620.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
regulation of intracellular transportGO:00323861950.015
regulation of protein processingGO:00706131500.015
plasma membrane organizationGO:00070091150.015
cytokine productionGO:00018162470.015
tripartite regional subdivisionGO:000735120.015
negative regulation of cell cycleGO:00457861930.015
compound eye developmentGO:004874910.015
negative regulation of cell differentiationGO:00455961710.015
blastoderm segmentationGO:000735020.015
regulation of cytoskeleton organizationGO:00514931770.015
cell fate determinationGO:000170930.015
interspecies interaction between organismsGO:00444191560.015
positive regulation of organelle organizationGO:00106381950.015
response to woundingGO:00096111680.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
regulation of secretion by cellGO:19035301770.015
blood circulationGO:00080151130.015
nucleocytoplasmic transportGO:00069131760.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
positive regulation of gtpase activityGO:00435471660.015
regulation of ion transportGO:00432691890.014
negative regulation of intracellular signal transductionGO:19025321830.014
regulation of cytoplasmic transportGO:19036491490.014
neurological system processGO:00508771630.014
negative regulation of interleukin 13 secretionGO:200066610.014
divalent metal ion transportGO:00708381520.014
dephosphorylationGO:00163112090.014
positive regulation of transferase activityGO:00513472270.014
organ formationGO:004864530.014
rna processingGO:00063962550.014
photoreceptor cell differentiationGO:004653020.014
positive regulation of cell differentiationGO:00455972110.014
nucleoside monophosphate metabolic processGO:00091231910.014
response to virusGO:00096151260.014
tissue homeostasisGO:0001894630.014
cell substrate adhesionGO:00315891320.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
sequestering of calcium ionGO:0051208170.014
protein modification by small protein conjugationGO:00324463420.014
regulation of cell morphogenesisGO:00226041530.014
response to cytokineGO:00340972320.014
positive regulation of kinase activityGO:00336742040.014
cellular metal ion homeostasisGO:00068751460.014
protein targetingGO:00066051870.014
cell growthGO:00160491600.014
positive regulation of mapk cascadeGO:00434101900.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
carbohydrate derivative biosynthetic processGO:19011372070.014
lipid biosynthetic processGO:00086101770.014
divalent inorganic cation transportGO:00725111580.014
negative regulation of proteolysisGO:00458611320.014
metencephalon developmentGO:002203720.014
cellular calcium ion homeostasisGO:00068741170.014
protein acylationGO:00435431380.014
cellular chemical homeostasisGO:00550821800.014
negative regulation of protein maturationGO:19033181420.014
organelle assemblyGO:00709251760.014
circadian behaviorGO:004851220.014
protein localization to membraneGO:00726571600.014
microtubule based processGO:00070172100.014
response to nitrogen compoundGO:19016981840.013
protein oligomerizationGO:00512591730.013
anion transmembrane transportGO:0098656760.013
regulation of immune responseGO:00507762010.013
calcium ion homeostasisGO:00550741220.013
calcium ion transportGO:00068161470.013
immune system developmentGO:00025201950.013
covalent chromatin modificationGO:00165692540.013
wnt signaling pathwayGO:00160551560.013
protein ubiquitinationGO:00165673140.013
lipid catabolic processGO:0016042840.013
atp metabolic processGO:00460341760.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
protein localization to plasma membraneGO:0072659930.013
carbohydrate metabolic processGO:00059752070.013
regulation of vesicle mediated transportGO:00606271300.013
nerve developmentGO:002167540.013
response to axon injuryGO:004867810.013
sex determinationGO:000753030.013
regulation of ras protein signal transductionGO:00465781550.013
dna repairGO:00062811980.013
circulatory system processGO:00030131130.013
negative regulation of icosanoid secretionGO:003230420.013
positive regulation of protein transportGO:00512221350.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
startle responseGO:000196430.013
cell cycle phase transitionGO:00447701730.013
negative regulation of protein processingGO:00109551420.013
positive regulation of protein kinase activityGO:00458601900.013
negative regulation of t helper 2 cell cytokine productionGO:200055220.013
immune effector processGO:00022521590.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
negative regulation of endopeptidase activityGO:0010951840.013
peptidyl tyrosine phosphorylationGO:00181081700.013
cellular protein complex assemblyGO:00436231880.013
establishment of protein localization to membraneGO:00901501210.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
organonitrogen compound biosynthetic processGO:19015662000.013
i kappab kinase nf kappab signalingGO:00072491660.013
vitamin e metabolic processGO:004236010.013
mitotic cell cycle phase transitionGO:00447721620.013
peptidyl tyrosine modificationGO:00182121700.013
inner ear morphogenesisGO:004247240.013
regulation of ion transmembrane transportGO:00347651320.013
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.013
thymus developmentGO:004853830.013
neuron differentiationGO:00301821380.013
positive regulation of secretionGO:00510471160.013
regulation of membrane potentialGO:0042391950.013
cofactor metabolic processGO:0051186870.013
regulation of cell growthGO:00015581350.013
epithelial cell proliferationGO:00506731280.013
regulation of heart rateGO:0002027380.013
mitochondrion organizationGO:00070051560.012
histone modificationGO:00165702510.012
inorganic anion transmembrane transportGO:0098661470.012
multicellular organismal response to stressGO:003355510.012
reproductive processGO:00224141060.012
lung alveolus developmentGO:004828640.012
regulation of homeostatic processGO:00328441210.012
multi organism cellular processGO:00447641560.012
cell morphogenesis involved in differentiationGO:00009041440.012
organic hydroxy compound metabolic processGO:19016151470.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
viral processGO:00160321460.012
regulation of ras gtpase activityGO:00323181280.012
monocarboxylic acid metabolic processGO:00327871850.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of multi organism processGO:00439001570.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
wound healingGO:00420601150.012
negative regulation of synaptic transmissionGO:005080520.012
urate transportGO:001574730.012
negative regulation of phosphorylationGO:00423261740.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
regulation of protein catabolic processGO:00421761550.012
sensory perception of painGO:001923340.012
lymphocyte activationGO:00466491330.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
tube closureGO:006060630.012
primary neural tube formationGO:001402030.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
single organism reproductive processGO:0044702980.012
neural tube closureGO:000184330.012
cellular response to organic cyclic compoundGO:00714071270.012
vitamin k catabolic processGO:004237720.012
leukocyte activationGO:00453211640.012
synaptic transmission cholinergicGO:000727120.012
hindlimb morphogenesisGO:003513720.012
blood vessel developmentGO:00015681720.012
generation of neuronsGO:00486991520.012
regulation of protein secretionGO:0050708860.012
regulation of cell activationGO:00508651250.012
positive regulation of cytokine productionGO:00018191670.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
ossificationGO:00015031210.012
positive regulation of cell cycleGO:00457871400.012
protein acetylationGO:00064731160.012
cell projection assemblyGO:00300311260.012
neural tube formationGO:000184130.011
cellular ion homeostasisGO:00068731680.011
sleepGO:003043120.011
establishment of protein localization to organelleGO:00725941720.011
organophosphate biosynthetic processGO:00904071630.011
positive regulation of intracellular transportGO:00323881040.011
neuroblast proliferationGO:000740540.011
keratinocyte differentiationGO:0030216360.011
viral life cycleGO:00190581320.011
stem cell divisionGO:001714520.011
positive regulation of secretion by cellGO:19035321080.011
positive regulation of proteolysisGO:00458621420.011
hemopoiesisGO:00300971800.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
regulation of heart growthGO:006042040.011
protein secretionGO:0009306980.011
fatty acid metabolic processGO:00066311150.011
detection of stimulusGO:0051606850.011
regulation of protein serine threonine kinase activityGO:00719001790.011
proteasomal protein catabolic processGO:00104981760.011
canonical wnt signaling pathwayGO:00600701160.011
endodermal cell fate commitmentGO:000171140.011
taxisGO:00423301570.011
regulation of actin cytoskeleton organizationGO:00329561160.011
inorganic anion transportGO:0015698600.011
regulation of dna metabolic processGO:00510521530.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathwayGO:003562540.011
salivary gland morphogenesisGO:000743540.011
positive regulation of acrosome reactionGO:200034440.011
single organismal cell cell adhesionGO:00163371480.011
Human
embryonic viscerocranium morphogenesisGO:004870310.011
regulation of growthGO:00400081650.011
cell projection morphogenesisGO:00488581290.011
meiotic chromosome segregationGO:004513240.011
multicellular organismal homeostasisGO:0048871670.011
nucleoside monophosphate catabolic processGO:00091251590.011
somatic stem cell maintenanceGO:003501940.011
defense response to fungusGO:005083240.011
monovalent inorganic cation transportGO:00156721280.011
syncytium formation by plasma membrane fusionGO:000076820.011
response to radiationGO:00093141510.011
cell divisionGO:00513011680.011
meiosis iGO:000712740.011
alcohol metabolic processGO:00060661140.011
endocytosisGO:00068971590.011
regulation of cell projection organizationGO:00313441070.011
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.011

FLG disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.023
inherited metabolic disorderDOID:6552420.023
musculoskeletal system diseaseDOID:172230.021
nervous system diseaseDOID:8634310.021
sensory system diseaseDOID:00501552030.021
disease of cellular proliferationDOID:145661740.018
immune system diseaseDOID:29141550.018
cancerDOID:1621670.016
organ system cancerDOID:00506861640.016
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
cardiovascular system diseaseDOID:12871060.016
central nervous system diseaseDOID:3311860.014
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
myopathyDOID:4231040.014
retinal diseaseDOID:56791180.013
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.012
disease of mental healthDOID:150700.011