Homo sapiens

0 known processes

SH2D1B

SH2 domain containing 1B

(Aliases: EAT2)

SH2D1B biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of natural killer cell mediated cytotoxicityGO:0045954110.628
Mouse
single organism membrane fusionGO:0044801370.246
positive regulation of natural killer cell mediated immunityGO:0002717120.200
Mouse
organelle fusionGO:0048284360.144
vesicle mediated transportGO:00161923710.107
vesicle organizationGO:0016050620.102
vesicle fusionGO:0006906170.098
actin filament based processGO:00300292240.086
leukocyte mediated immunityGO:0002443590.076
Mouse
negative regulation of protein metabolic processGO:00512483910.073
Mouse
innate immune responseGO:00450871780.068
Mouse
determination of adult lifespanGO:000834020.068
single organism membrane organizationGO:00448022680.066
myeloid cell differentiationGO:00300991170.061
regulation of immune effector processGO:0002697910.056
Mouse
multicellular organismal agingGO:001025930.053
hemopoiesisGO:00300971800.053
regulation of innate immune responseGO:0045088970.050
Mouse
positive regulation of cell deathGO:00109422630.049
immune system developmentGO:00025201950.047
cell killingGO:0001906340.047
Mouse
organophosphate catabolic processGO:00464344300.047
post embryonic developmentGO:000979120.047
membrane fusionGO:0061025430.046
actin filament organizationGO:00070151280.045
negative regulation of multicellular organismal processGO:00512413170.045
Mouse
regulation of vesicle mediated transportGO:00606271300.045
actin cytoskeleton organizationGO:00300362070.043
cytokine productionGO:00018162470.043
Mouse
segmentationGO:003528240.042
purine ribonucleotide catabolic processGO:00091544040.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.040
positive regulation of immune effector processGO:0002699400.040
Mouse
nucleotide catabolic processGO:00091664080.039
ribonucleoside triphosphate metabolic processGO:00091994120.039
defense responseGO:00069523150.039
Mouse
ribonucleotide catabolic processGO:00092614050.039
regulation of kinase activityGO:00435493140.038
regulation of protein localizationGO:00328802960.038
natural killer cell mediated immunityGO:0002228230.038
Mouse
lymphocyte mediated immunityGO:0002449480.037
Mouse
regulation of cellular amine metabolic processGO:0033238110.037
negative regulation of catalytic activityGO:00430863350.036
nucleoside phosphate catabolic processGO:19012924120.036
natural killer cell mediated cytotoxicityGO:0042267230.035
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
regulation of purine nucleotide metabolic processGO:19005422640.033
lipid metabolic processGO:00066293810.033
negative regulation of cellular protein metabolic processGO:00322693530.032
Mouse
guanosine containing compound catabolic processGO:19010692390.032
female gamete generationGO:000729220.032
negative regulation of monocyte differentiationGO:004565630.031
ras protein signal transductionGO:0007265730.031
positive regulation of cellular catabolic processGO:00313312840.031
ribonucleoside catabolic processGO:00424544060.031
associative learningGO:000830610.031
regulation of lymphocyte mediated immunityGO:0002706330.030
Mouse
regulation of proteolysisGO:00301622930.030
regulation of transferase activityGO:00513383550.030
purine ribonucleoside catabolic processGO:00461303980.029
positive regulation of lymphocyte activationGO:0051251730.029
purine nucleoside catabolic processGO:00061523980.029
motor neuron axon guidanceGO:000804520.029
replacement ossificationGO:003607510.029
response to oxygen containing compoundGO:19017003690.028
regulation of establishment of protein localizationGO:00702012420.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
cell adhesionGO:00071553250.028
gtp metabolic processGO:00460392390.027
activation of immune responseGO:00022531140.027
regulation of vesicle fusionGO:003133850.027
regulation of cellular response to stressGO:00801352440.027
regulation of protein transportGO:00512232130.026
purine containing compound catabolic processGO:00725234110.026
positive regulation of cytokine productionGO:00018191670.026
regulation of intracellular transportGO:00323861950.026
cellular macromolecular complex assemblyGO:00346223240.026
negative regulation of hydrolase activityGO:00513461820.026
lymphocyte activationGO:00466491330.026
Mouse
regulation of osteoclast differentiationGO:0045670180.026
neuromuscular junction developmentGO:000752830.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
regulation of protein maturationGO:19033171500.025
protein processingGO:00164852260.025
hematopoietic or lymphoid organ developmentGO:00485341860.025
regulation of reactive oxygen species metabolic processGO:2000377410.025
negative regulation of phosphate metabolic processGO:00459362670.025
Mouse
regulation of protein processingGO:00706131500.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
nucleoside triphosphate catabolic processGO:00091433940.024
cytoplasmic transportGO:00164823790.024
mitotic cell cycle processGO:19030472860.023
microtubule based processGO:00070172100.023
positive regulation of immune responseGO:00507781590.023
Mouse
nucleoside triphosphate metabolic processGO:00091414220.022
cellular macromolecule catabolic processGO:00442653800.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
cellular response to dna damage stimulusGO:00069743790.022
regulation of peptidase activityGO:00525471800.022
phospholipid metabolic processGO:0006644990.022
cellular component morphogenesisGO:00329893140.022
transmembrane transportGO:00550853990.022
dephosphorylationGO:00163112090.022
oogenesisGO:004847720.022
positive regulation of transportGO:00510503360.022
cellular amino acid metabolic processGO:00065201160.021
memoryGO:000761330.021
negative regulation of immune responseGO:0050777400.021
Mouse
positive regulation of cell differentiationGO:00455972110.021
blastoderm segmentationGO:000735020.021
regulation of gtpase activityGO:00430871800.021
chemical homeostasisGO:00488783060.021
regulation of cellular ketone metabolic processGO:0010565500.021
cellular lipid metabolic processGO:00442553030.021
locomotory behaviorGO:000762610.021
regulation of gtp catabolic processGO:00331241800.021
immune responseGO:00069553070.021
Mouse
regulation of response to external stimulusGO:00321012220.020
reactive oxygen species biosynthetic processGO:190340940.020
regulation of nucleotide metabolic processGO:00061402690.020
response to growth factorGO:00708482050.020
regulation of mapk cascadeGO:00434082620.020
cation transportGO:00068123310.020
negative regulation of proteolysisGO:00458611320.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
ion transmembrane transportGO:00342203380.020
organophosphate biosynthetic processGO:00904071630.020
regulation of cellular amino acid metabolic processGO:000652160.020
regulation of cytoplasmic transportGO:19036491490.020
maintenance of locationGO:00512351120.020
regulation of response to woundingGO:19030341010.020
embryonic viscerocranium morphogenesisGO:004870310.020
regulation of cell cycle processGO:00105642660.020
regulation of protein kinase activityGO:00458592890.020
chromatin organizationGO:00063253510.019
immune response regulating cell surface receptor signaling pathwayGO:0002768510.019
Mouse
endochondral bone morphogenesisGO:006035030.019
immune response activating cell surface receptor signaling pathwayGO:0002429450.019
regulation of apoptotic signaling pathwayGO:20012331750.019
peptidyl tyrosine phosphorylationGO:00181081700.019
Mouse
negative regulation of cellular amino acid metabolic processGO:004576320.019
multicellular organismal homeostasisGO:0048871670.019
response to virusGO:00096151260.019
regulation of cytokine productionGO:00018172320.019
Mouse
system processGO:00030083490.019
regulation of myeloid leukocyte mediated immunityGO:000288640.019
positive regulation of catabolic processGO:00098963100.019
oxidation reduction processGO:00551143960.019
protein catabolic processGO:00301633250.019
endocytosisGO:00068971590.018
negative regulation of phosphorus metabolic processGO:00105632670.018
Mouse
protein maturationGO:00516042330.018
covalent chromatin modificationGO:00165692540.018
positive regulation of phosphorylationGO:00423273940.018
Mouse
regulation of cell activationGO:00508651250.018
Mouse
regulation of myeloid cell differentiationGO:0045637810.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
response to organic cyclic compoundGO:00140702040.018
t cell activationGO:0042110990.018
protein oligomerizationGO:00512591730.017
positive regulation of lymphocyte mediated immunityGO:0002708230.017
Mouse
oocyte developmentGO:004859910.017
modification dependent macromolecule catabolic processGO:00436322120.017
posttranscriptional regulation of gene expressionGO:00106082130.017
proteasomal protein catabolic processGO:00104981760.017
negative regulation of peptidase activityGO:0010466910.017
photoreceptor cell differentiationGO:004653020.017
positive regulation of developmental processGO:00510943140.017
regulation of cell motilityGO:20001452990.017
positive regulation of cellular amine metabolic processGO:003324070.017
cellular protein complex assemblyGO:00436231880.017
positive regulation of nucleotide catabolic processGO:00308131850.017
positive regulation of protein transportGO:00512221350.017
peptidyl tyrosine modificationGO:00182121700.017
Mouse
negative regulation of cell deathGO:00605483450.017
small molecule biosynthetic processGO:00442831570.017
divalent metal ion transportGO:00708381520.017
sequestering of calcium ionGO:0051208170.016
positive regulation of organelle organizationGO:00106381950.016
mitotic cell cycle phase transitionGO:00447721620.016
regulation of astrocyte chemotaxisGO:200045810.016
biological adhesionGO:00226103310.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
anterior posterior axis specificationGO:000994820.016
regulation of cellular component movementGO:00512703340.016
organonitrogen compound biosynthetic processGO:19015662000.016
positive regulation of cellular amino acid metabolic processGO:004576430.016
positive regulation of gtpase activityGO:00435471660.016
lipid biosynthetic processGO:00086101770.016
chemokine c c motif ligand 11 productionGO:007195410.016
carbohydrate derivative biosynthetic processGO:19011372070.015
modification dependent protein catabolic processGO:00199412090.015
response to lipidGO:00339932060.015
protein autophosphorylationGO:00467771230.015
organ formationGO:004864530.015
cardiac muscle cell contractionGO:008600340.015
response to nitrogen compoundGO:19016981840.015
cell morphogenesisGO:00009022960.015
nervous system developmentGO:00073992930.015
cellular protein catabolic processGO:00442572610.015
spermatid differentiationGO:004851540.015
response to fungusGO:000962040.015
cell cycle phase transitionGO:00447701730.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
immune effector processGO:00022521590.015
Mouse
negative regulation of protein processingGO:00109551420.015
negative regulation of apoptotic processGO:00430663160.015
anterior posterior axis specification embryoGO:000859520.015
ubiquitin dependent protein catabolic processGO:00065112060.014
adult locomotory behaviorGO:000834410.014
rna processingGO:00063962550.014
negative regulation of homeostatic processGO:0032845590.014
regulation of nucleoside metabolic processGO:00091182090.014
regulation of cell growthGO:00015581350.014
positive regulation of nucleotide metabolic processGO:00459812300.014
neurological system processGO:00508771630.014
reactive oxygen species metabolic processGO:0072593750.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
Mouse
purine ribonucleoside metabolic processGO:00461284370.014
somitogenesisGO:000175620.014
mitotic cell cycleGO:00002783260.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
long term memoryGO:000761620.014
regulation of ras protein signal transductionGO:00465781550.014
chromatin modificationGO:00165682980.014
regulation of microtubule based processGO:0032886740.014
positive regulation of transferase activityGO:00513472270.014
establishment of tissue polarityGO:000716430.014
positive regulation of cell killingGO:0031343190.014
Mouse
regulation of cell cycleGO:00517263930.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
amine metabolic processGO:0009308440.014
atp metabolic processGO:00460341760.014
regenerationGO:003109940.014
ribonucleoside triphosphate catabolic processGO:00092033910.014
establishment of planar polarityGO:000173630.014
cellular response to endogenous stimulusGO:00714953360.014
nucleoside monophosphate metabolic processGO:00091231910.014
nucleocytoplasmic transportGO:00069131760.014
divalent inorganic cation transportGO:00725111580.014
metencephalon developmentGO:002203720.014
response to bacteriumGO:00096171440.014
syncytium formation by plasma membrane fusionGO:000076820.014
regulation of cell migrationGO:00303342890.013
regulation of endopeptidase activityGO:00525481700.013
negative regulation of protein modification processGO:00314002000.013
Mouse
gtp catabolic processGO:00061842370.013
tissue migrationGO:00901301190.013
melanin metabolic processGO:000658210.013
response to organonitrogen compoundGO:00102431560.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
oocyte differentiationGO:000999420.013
membrane organizationGO:00610242920.013
cellular response to hormone stimulusGO:00328701250.013
cation transmembrane transportGO:00986552380.013
inorganic ion transmembrane transportGO:00986602310.013
morphogenesis of a polarized epitheliumGO:000173830.013
positive regulation of protein kinase activityGO:00458601900.013
regulation of nucleotide catabolic processGO:00308112050.013
single organism carbohydrate metabolic processGO:00447231930.013
cell fate determinationGO:000170930.013
tissue regenerationGO:004224630.013
regulation of intracellular protein transportGO:00331571230.013
thymus developmentGO:004853830.013
growthGO:00400072020.013
histone modificationGO:00165702510.013
negative regulation of endopeptidase activityGO:0010951840.013
positive regulation of lymphocyte proliferationGO:0050671460.013
morphogenesis of embryonic epitheliumGO:001633140.013
regulation of calcium ion transport into cytosolGO:0010522330.013
visual behaviorGO:000763220.013
regulation of ras gtpase activityGO:00323181280.013
glycoprotein metabolic processGO:00091001100.013
response to transforming growth factor betaGO:0071559940.012
tongue developmentGO:004358610.012
cellular ketone metabolic processGO:0042180800.012
peripheral nervous system developmentGO:000742220.012
negative regulation of cell cycleGO:00457861930.012
regulation of protein catabolic processGO:00421761550.012
embryonic forelimb morphogenesisGO:003511540.012
regulation of cell morphogenesisGO:00226041530.012
negative regulation of protein maturationGO:19033181420.012
cell growthGO:00160491600.012
regulation of purine nucleotide catabolic processGO:00331212050.012
cell cycle checkpointGO:00000751170.012
compound eye developmentGO:004874910.012
methylationGO:00322591060.012
cell part morphogenesisGO:00329901370.012
positive regulation of immune system processGO:00026842830.012
Mouse
immune response activating signal transductionGO:0002757900.012
positive regulation of nucleoside metabolic processGO:00459791860.012
glycerophospholipid metabolic processGO:0006650840.012
organic hydroxy compound metabolic processGO:19016151470.012
regulation of multi organism processGO:00439001570.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
microtubule cytoskeleton organizationGO:00002261760.012
apoptotic signaling pathwayGO:00971902680.012
negative regulation of reactive oxygen species biosynthetic processGO:190342710.012
regulation of meiotic cell cycleGO:005144540.012
trabecula morphogenesisGO:006138320.012
positive regulation of kinase activityGO:00336742040.012
protein acylationGO:00435431380.012
positive regulation of leukocyte differentiationGO:1902107370.012
negative regulation of cellular component organizationGO:00511292350.012
autophagyGO:0006914880.012
actin mediated cell contractionGO:0070252120.012
endosomal transportGO:00161971290.012
cranial nerve developmentGO:002154540.012
regulation of cytokine secretionGO:0050707570.012
circadian behaviorGO:004851220.012
nerve developmentGO:002167540.012
axis elongationGO:000340140.012
startle responseGO:000196430.012
regulation of growthGO:00400081650.011
negative regulation of programmed cell deathGO:00430693210.011
translationGO:00064121320.011
intracellular protein transportGO:00068862700.011
heart formationGO:006091420.011
tissue homeostasisGO:0001894630.011
negative regulation of organelle organizationGO:00106391260.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
embryonic epithelial tube formationGO:000183840.011
second messenger mediated signalingGO:0019932780.011
regulation of myeloid leukocyte differentiationGO:0002761390.011
protein targetingGO:00066051870.011
negative regulation of reactive oxygen species metabolic processGO:2000378110.011
chemotaxisGO:00069351570.011
response to peptideGO:1901652650.011
negative regulation of intracellular signal transductionGO:19025321830.011
regulation of chromosome organizationGO:00330441030.011
regulation of rho protein signal transductionGO:0035023790.011
protein localization to organelleGO:00333652800.011
nucleoside monophosphate catabolic processGO:00091251590.011
convergent extensionGO:006002610.011
positive regulation of secretionGO:00510471160.011
protein localization to nucleusGO:00345041360.011
regulation of endothelial cell proliferationGO:0001936560.011
tripartite regional subdivisionGO:000735120.011
receptor metabolic processGO:0043112810.011
rhythmic behaviorGO:000762220.011
response to external biotic stimulusGO:00432072610.011
hindbrain developmentGO:003090230.011
humoral immune responseGO:0006959490.011
guanosine containing compound metabolic processGO:19010682440.011
regulation of cellular protein catabolic processGO:1903362960.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.011
nuclear transportGO:00511691790.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
wnt signaling pathwayGO:00160551560.011
response to cytokineGO:00340972320.011
response to abiotic stimulusGO:00096283360.011
negative regulation of hydrogen peroxide metabolic processGO:001072730.011
regulation of anatomical structure morphogenesisGO:00226032860.011
stress activated mapk cascadeGO:0051403930.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
atp catabolic processGO:00062001570.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
positive regulation of locomotionGO:00400171860.011
glycerolipid metabolic processGO:00464861070.011
single organism cellular localizationGO:19025803320.010
limbic system developmentGO:002176130.010
glycosyl compound catabolic processGO:19016584130.010
carbohydrate metabolic processGO:00059752070.010
regulation of transmembrane transportGO:00347621390.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
cellular response to oxygen containing compoundGO:19017012760.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
b cell proliferationGO:0042100220.010
regulation of cellular component biogenesisGO:00440872810.010
dna repairGO:00062811980.010
eosinophil activation involved in immune responseGO:000227820.010
primary neural tube formationGO:001402030.010
nitrogen compound transportGO:00717051910.010
inorganic cation transmembrane transportGO:00986621940.010
positive regulation of intracellular transportGO:00323881040.010
regulation of meiosisGO:004002030.010
protein homooligomerizationGO:00512601000.010
spermatid developmentGO:000728640.010
monocarboxylic acid metabolic processGO:00327871850.010
regulation of protein secretionGO:0050708860.010
organelle assemblyGO:00709251760.010
meiosis iGO:000712740.010
regulation of cell cycle phase transitionGO:19019871260.010
establishment of protein localization to organelleGO:00725941720.010
regulation of defense responseGO:00313471540.010
Mouse
cerebellum developmentGO:002154920.010
rna interferenceGO:001624640.010
protein polymerizationGO:0051258710.010
sleepGO:003043120.010
reactive nitrogen species metabolic processGO:200105730.010
nuclear exportGO:0051168690.010
cellular response to lipidGO:00713961270.010
positive regulation of vasoconstrictionGO:004590730.010
regulation of sensory perceptionGO:005193130.010
macromolecule methylationGO:0043414970.010

SH2D1B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.028
disease of metabolismDOID:00146672950.024
cancerDOID:1621670.021
disease of cellular proliferationDOID:145661740.021
inherited metabolic disorderDOID:6552420.019
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
organ system cancerDOID:00506861640.018
eye diseaseDOID:56141490.016
eye and adnexa diseaseDOID:14921500.016
immune system diseaseDOID:29141550.016
cardiovascular system diseaseDOID:12871060.015
central nervous system diseaseDOID:3311860.014
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.013
retinal diseaseDOID:56791180.012
myopathyDOID:4231040.012
retinal degenerationDOID:8466890.010