Homo sapiens

83 known processes

IRAK2

interleukin-1 receptor-associated kinase 2

(Aliases: IRAK-2,MGC150550)

IRAK2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
interleukin 6 productionGO:0032635371.000
Human
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555441.000
Human
cellular response to bacterial lipoproteinGO:007122031.000
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556201.000
Human
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.999
negative regulation of tumor necrosis factor productionGO:0032720200.999
Human
activation of innate immune responseGO:0002218550.999
Human
innate immune response activating signal transductionGO:0002758480.999
Human
toll like receptor 2 signaling pathwayGO:003413440.998
Human
regulation of cytokine productionGO:00018172320.996
Human
response to biotic stimulusGO:00096072760.996
Human Mouse
negative regulation of interleukin 6 productionGO:0032715130.995
Human
negative regulation of nf kappab transcription factor activityGO:0032088510.995
positive regulation of toll like receptor 4 signaling pathwayGO:003414560.995
activation of protein kinase activityGO:0032147900.995
Human
cytokine productionGO:00018162470.994
Human
regulation of tumor necrosis factor productionGO:0032680430.994
Human
response to peptidoglycanGO:003249430.994
cellular response to lipopolysaccharideGO:0071222570.994
Human Mouse
negative regulation of multicellular organismal processGO:00512413170.993
Human
cellular response to biotic stimulusGO:0071216710.993
Human Mouse
cytokine mediated signaling pathwayGO:00192211090.993
pattern recognition receptor signaling pathwayGO:0002221480.992
Human
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.992
growth of symbiont in hostGO:004411710.992
cellular response to molecule of bacterial originGO:0071219620.988
Human Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.986
positive regulation of toll like receptor signaling pathwayGO:0034123100.984
tumor necrosis factor superfamily cytokine productionGO:0071706450.983
Human
positive regulation of innate immune responseGO:0045089790.979
Human
lipopolysaccharide mediated signaling pathwayGO:0031663260.978
Human Mouse
negative regulation of reactive oxygen species biosynthetic processGO:190342710.975
mapk cascadeGO:00001652880.974
Human
response to bacteriumGO:00096171440.974
Human Mouse
response to molecule of bacterial originGO:0002237820.973
Human Mouse
response to lipoteichoic acidGO:007039130.973
positive regulation of defense responseGO:0031349870.970
Human
response to lipopolysaccharideGO:0032496700.967
Human Mouse
positive regulation of nik nf kappab signalingGO:1901224100.966
Human
immune response activating signal transductionGO:0002757900.965
Human
i kappab kinase nf kappab signalingGO:00072491660.964
Human
regulation of nik nf kappab signalingGO:1901222110.964
Human
regulation of interleukin 6 productionGO:0032675370.962
Human
toll like receptor signaling pathwayGO:0002224250.961
Human
response to other organismGO:00517072610.961
Human Mouse
regulation of protein kinase activityGO:00458592890.958
Human
activation of nf kappab inducing kinase activityGO:000725090.958
Human
positive regulation of phosphorylationGO:00423273940.951
Human
tumor necrosis factor productionGO:0032640430.950
Human
positive regulation of interleukin 23 productionGO:003274740.950
regulation of immune responseGO:00507762010.949
Human
positive regulation of lipid storageGO:0010884100.944
positive regulation of protein kinase activityGO:00458601900.943
Human
interleukin 1 mediated signaling pathwayGO:0070498120.940
negative regulation of protein serine threonine kinase activityGO:0071901570.934
Human
positive regulation of toll like receptor 2 signaling pathwayGO:003413720.922
response to external biotic stimulusGO:00432072610.917
Human Mouse
regulation of mapk cascadeGO:00434082620.916
Human
cellular response to oxygen containing compoundGO:19017012760.915
Human Mouse
regulation of toll like receptor signaling pathwayGO:0034121170.910
cellular response to lipidGO:00713961270.905
Human Mouse
immune response regulating signaling pathwayGO:0002764970.904
Human
chemokine biosynthetic processGO:004203340.903
response to cytokineGO:00340972320.901
modulation of growth of symbiont involved in interaction with hostGO:004414420.900
regulation of interleukin 12 productionGO:0032655150.899
Human
growth involved in symbiotic interactionGO:004411020.897
signal transduction by phosphorylationGO:00230142970.887
Human
positive regulation of toll like receptor 3 signaling pathwayGO:003414110.879
growth of symbiont involved in interaction with hostGO:004411620.876
regulation of transferase activityGO:00513383550.876
Human
activation of immune responseGO:00022531140.874
Human
positive regulation of nf kappab transcription factor activityGO:0051092810.873
response to interleukin 1GO:0070555470.868
regulation of innate immune responseGO:0045088970.859
Human
regulation of kinase activityGO:00435493140.849
Human
negative regulation of macrophage cytokine productionGO:001093630.846
chemokine metabolic processGO:005075540.840
response to lipidGO:00339932060.829
Human Mouse
regulation of i kappab kinase nf kappab signalingGO:00431221620.817
Human
reactive nitrogen species metabolic processGO:200105730.816
negative regulation of protein complex disassemblyGO:0043242200.814
Human
response to oxygen containing compoundGO:19017003690.813
Human Mouse
positive regulation of protein phosphorylationGO:00019343130.813
Human
antifungal humoral responseGO:001973220.811
regulation of interleukin 17 productionGO:0032660120.804
positive regulation of mapk cascadeGO:00434101900.802
positive regulation of immune responseGO:00507781590.797
Human
defense responseGO:00069523150.797
Human
interleukin 17 productionGO:0032620120.788
regulation of toll like receptor 2 signaling pathwayGO:003413520.785
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.780
negative regulation of reactive oxygen species metabolic processGO:2000378110.778
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.777
innate immune responseGO:00450871780.774
Human
positive regulation of catabolic processGO:00098963100.764
regulation of chemokine biosynthetic processGO:004507340.761
regulation of protein serine threonine kinase activityGO:00719001790.752
Human
negative regulation of cytokine productionGO:0001818820.740
Human
positive regulation of chemokine productionGO:0032722220.723
smooth muscle cell proliferationGO:0048659280.709
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.704
positive regulation of cytokine biosynthetic processGO:0042108250.700
positive regulation of map kinase activityGO:0043406800.700
response to bacterial lipoproteinGO:003249330.694
positive regulation of chemokine biosynthetic processGO:004508030.691
toll like receptor 4 signaling pathwayGO:0034142120.690
regulation of fat cell differentiationGO:0045598230.689
cellular response to cytokine stimulusGO:00713451810.685
regulation of reactive oxygen species metabolic processGO:2000377410.684
positive regulation of jun kinase activityGO:0043507230.677
positive regulation of kinase activityGO:00336742040.676
Human
regulation of response to cytokine stimulusGO:0060759460.642
positive regulation of transferase activityGO:00513472270.639
Human
negative regulation of cholesterol transportGO:003237580.638
response to abiotic stimulusGO:00096283360.624
response to diacyl bacterial lipopeptideGO:007172420.591
negative regulation of interleukin 12 productionGO:003269560.590
Human
immune responseGO:00069553070.586
Human
organic hydroxy compound transportGO:0015850630.568
negative regulation of growthGO:0045926970.554
nitric oxide biosynthetic processGO:0006809200.545
reactive oxygen species biosynthetic processGO:190340940.542
regulation of nitric oxide biosynthetic processGO:0045428170.540
lipid localizationGO:00108761060.519
negative regulation of mapk cascadeGO:0043409560.511
Human
jnk cascadeGO:0007254800.509
cellular response to bacterial lipopeptideGO:007122130.497
positive regulation of smooth muscle cell proliferationGO:0048661140.495
negative regulation of cholesterol effluxGO:009037020.494
regulation of cytokine mediated signaling pathwayGO:0001959410.492
detection of diacyl bacterial lipopeptideGO:004249620.476
i kappab phosphorylationGO:000725270.472
regulation of cytokine production involved in immune responseGO:0002718220.462
positive regulation of immune system processGO:00026842830.460
Human
positive regulation of jnk cascadeGO:0046330520.458
negative regulation of mitotic cell cycle phase transitionGO:1901991850.457
cholesterol effluxGO:0033344280.456
regulation of reactive oxygen species biosynthetic processGO:190342630.442
negative regulation of growth of symbiont involved in interaction with hostGO:004414620.440
positive regulation of developmental processGO:00510943140.440
regulation of smooth muscle cell proliferationGO:0048660280.436
macrophage cytokine productionGO:001093440.428
regulation of jun kinase activityGO:0043506270.427
regulation of map kinase activityGO:00434051080.424
Human
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.402
Human
immune effector processGO:00022521590.402
positive regulation of interferon alpha biosynthetic processGO:004535640.397
interleukin 12 productionGO:0032615150.385
Human
regulation of cell cycleGO:00517263930.380
fat cell differentiationGO:0045444320.380
defense response to bacteriumGO:0042742630.375
cellular component disassemblyGO:0022411920.370
Human
detection of bacterial lipoproteinGO:004249430.363
regulation of stress activated mapk cascadeGO:0032872840.360
macromolecular complex disassemblyGO:0032984600.359
Human
reactive oxygen species metabolic processGO:0072593750.358
negative regulation of protein catabolic processGO:0042177590.354
Human
production of molecular mediator of immune responseGO:0002440370.352
cellular response to uvGO:0034644320.350
type i interferon biosynthetic processGO:004535140.350
negative regulation of mitotic cell cycleGO:00459301020.341
negative regulation of protein phosphorylationGO:00019331400.339
Human
negative regulation of nitric oxide biosynthetic processGO:004501950.332
regulation of stress activated protein kinase signaling cascadeGO:0070302850.325
positive regulation of cellular catabolic processGO:00313312840.320
positive regulation of stress activated mapk cascadeGO:0032874600.319
positive regulation of protein bindingGO:0032092240.318
negative regulation of protein metabolic processGO:00512483910.314
Human
regulation of mitotic cell cycleGO:00073461890.310
negative regulation of cytokine production involved in immune responseGO:0002719130.305
negative regulation of cytokine mediated signaling pathwayGO:0001960220.303
response to triacyl bacterial lipopeptideGO:007172520.300
regulation of immune effector processGO:0002697910.291
cellular response to abiotic stimulusGO:00712141170.290
regulation of jnk cascadeGO:0046328730.290
response to fungusGO:000962040.286
regulation of autophagyGO:0010506520.279
negative regulation of phosphorus metabolic processGO:00105632670.271
Human
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.269
positive regulation of cell differentiationGO:00455972110.266
regulation of cell cycle processGO:00105642660.266
negative regulation of cellular protein metabolic processGO:00322693530.263
Human
regulation of growthGO:00400081650.262
protein autophosphorylationGO:00467771230.256
Human
mitotic cell cycleGO:00002783260.248
positive regulation of cell proliferationGO:00082843010.244
stress activated protein kinase signaling cascadeGO:0031098940.243
stress activated mapk cascadeGO:0051403930.242
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.241
regulation of cellular amino acid metabolic processGO:000652160.239
negative regulation of cell cycle g1 s phase transitionGO:1902807290.239
negative regulation of cell cycle phase transitionGO:1901988890.239
response to organonitrogen compoundGO:00102431560.236
positive regulation of leukocyte proliferationGO:0070665480.232
lipid transportGO:0006869900.232
negative regulation of cellular component organizationGO:00511292350.231
Human
autophagyGO:0006914880.228
positive regulation of interferon beta biosynthetic processGO:004535940.228
cell growthGO:00160491600.217
negative regulation of cell cycleGO:00457861930.217
positive regulation of cytokine productionGO:00018191670.217
regulation of cell motilityGO:20001452990.215
type i interferon productionGO:0032606270.213
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.213
rna stabilizationGO:0043489180.213
hemopoiesisGO:00300971800.209
positive regulation of interleukin 6 productionGO:0032755210.204
positive regulation of interleukin 8 productionGO:0032757360.200
nitric oxide metabolic processGO:0046209220.198
positive regulation of lymphocyte activationGO:0051251730.197
protein oligomerizationGO:00512591730.187
Human
interferon alpha biosynthetic processGO:004534940.186
regulation of cell growthGO:00015581350.185
cellular response to diacyl bacterial lipopeptideGO:007172620.184
positive regulation of autophagyGO:0010508240.182
protein catabolic processGO:00301633250.182
Human
nucleotide binding oligomerization domain containing signaling pathwayGO:007042340.182
positive regulation of mononuclear cell proliferationGO:0032946470.177
immunoglobulin secretionGO:004830510.175
cellular response to radiationGO:0071478650.173
regulation of cell activationGO:00508651250.173
cytokine production involved in immune responseGO:0002367270.170
lymphocyte mediated immunityGO:0002449480.170
primary neural tube formationGO:001402030.166
defense response to gram positive bacteriumGO:0050830290.163
defense response to fungusGO:005083240.162
regulation of cell cycle phase transitionGO:19019871260.162
regulation of protein bindingGO:0043393660.160
negative regulation of intracellular signal transductionGO:19025321830.157
Human
lymphocyte activationGO:00466491330.156
response to radiationGO:00093141510.156
response to uvGO:0009411730.152
regulation of cytokine biosynthetic processGO:0042035350.149
lipid storageGO:0019915280.147
negative regulation of phosphorylationGO:00423261740.146
Human
epithelium developmentGO:00604292270.145
regulation of rna stabilityGO:0043487230.143
cholesterol transportGO:0030301390.142
regulation of cellular response to stressGO:00801352440.142
regulation of leukocyte activationGO:00026941150.140
immune system developmentGO:00025201950.139
regulation of cell cycle g1 s phase transitionGO:1902806420.139
regulation of protein transportGO:00512232130.132
protein complex disassemblyGO:0043241520.131
Human
g1 s transition of mitotic cell cycleGO:0000082780.130
cellular amine metabolic processGO:0044106410.127
positive regulation of interleukin 6 biosynthetic processGO:004541010.127
cellular response to triacyl bacterial lipopeptideGO:007172720.127
positive regulation of humoral immune responseGO:000292230.124
growthGO:00400072020.124
chemokine productionGO:0032602320.123
myeloid leukocyte cytokine productionGO:006108250.123
negative regulation of catalytic activityGO:00430863350.121
Human
negative regulation of protein modification processGO:00314002000.120
Human
regulation of tolerance inductionGO:000264340.120
leukocyte proliferationGO:0070661740.114
mitotic cell cycle phase transitionGO:00447721620.113
negative regulation of multi organism processGO:0043901920.112
regulation of lipid storageGO:0010883210.109
response to heatGO:0009408210.107
response to nitrogen compoundGO:19016981840.106
negative regulation of cell growthGO:0030308830.105
response to organic cyclic compoundGO:00140702040.105
detection of bacterial lipopeptideGO:007034030.105
positive regulation of protein serine threonine kinase activityGO:00719021190.103
Human
inflammatory responseGO:0006954790.102
regulation of lymphocyte proliferationGO:0050670640.102
negative regulation of catabolic processGO:00098951040.102
Human
positive regulation of interleukin 17 productionGO:003274080.101
regulation of apoptotic signaling pathwayGO:20012331750.100
regulation of chemokine c x c motif ligand 2 productionGO:200034120.100
cellular response to oxygen levelsGO:0071453550.099
mitotic cell cycle processGO:19030472860.099
negative regulation of immune responseGO:0050777400.098
muscle cell proliferationGO:0033002350.097
mrna stabilizationGO:0048255180.097
positive regulation of lymphocyte proliferationGO:0050671460.097
positive regulation of apoptotic processGO:00430652460.097
positive regulation of chemotaxisGO:0050921570.097
response to light stimulusGO:0009416870.097
negative regulation of cell cycle processGO:00109481210.096
cell activationGO:00017752130.094
cellular response to heatGO:0034605140.094
morphogenesis of embryonic epitheliumGO:001633140.093
regulation of locomotionGO:00400123290.092
regulation of production of molecular mediator of immune responseGO:0002700250.091
cytokine biosynthetic processGO:0042089370.089
negative regulation of map kinase activityGO:0043407270.087
Human
regulation of nucleocytoplasmic transportGO:0046822980.087
extrinsic apoptotic signaling pathwayGO:00971911190.087
regulation of macrophage cytokine productionGO:001093540.087
regulation of defense responseGO:00313471540.086
Human
negative regulation of immune system processGO:00026831360.085
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.085
cellular response to external stimulusGO:00714961110.084
cell cycle phase transitionGO:00447701730.083
positive regulation of cellular amino acid metabolic processGO:004576430.082
regulation of g1 s transition of mitotic cell cycleGO:2000045400.082
regulation of interferon alpha biosynthetic processGO:004535440.082
negative regulation of production of molecular mediator of immune responseGO:0002701130.080
nik nf kappab signalingGO:0038061120.077
Human
negative regulation of phosphate metabolic processGO:00459362670.077
Human
response to bacterial lipopeptideGO:007033930.076
positive regulation of t cell cytokine productionGO:000272640.076
response to hypoxiaGO:0001666960.075
toll like receptor 3 signaling pathwayGO:003413840.073
protein ubiquitinationGO:00165673140.073
cell cycle g1 s phase transitionGO:0044843800.072
sterol transportGO:0015918390.072
cellular response to lipoteichoic acidGO:007122330.071
regulation of lipid transportGO:0032368440.071
nf kappab import into nucleusGO:0042348220.070
cellular amino acid metabolic processGO:00065201160.070
cytokine metabolic processGO:0042107380.070
regulation of secretionGO:00510461940.070
regulation of toll like receptor 3 signaling pathwayGO:003413920.070
epithelial cell differentiationGO:00308551410.069
positive regulation of interleukin 8 biosynthetic processGO:004541680.068
ribonucleoside catabolic processGO:00424544060.068
regulation of immunoglobulin productionGO:000263740.068
positive regulation of nf kappab import into nucleusGO:0042346130.067
regulation of protein homodimerization activityGO:004349690.067
regulation of cellular amine metabolic processGO:0033238110.067
negative regulation of growth of symbiont in hostGO:004413010.066
maintenance of locationGO:00512351120.065
neural tube formationGO:000184130.065
interspecies interaction between organismsGO:00444191560.064
regulation of mrna stabilityGO:0043488230.064
nucleoside triphosphate metabolic processGO:00091414220.064
cellular response to light stimulusGO:0071482340.064
negative regulation of tumor necrosis factor mediated signaling pathwayGO:001080470.062
negative regulation of defense responseGO:0031348470.061
regulation of sterol transportGO:0032371210.060
regulation of cell migrationGO:00303342890.059
interleukin 1 productionGO:0032612260.058
3 utr mediated mrna stabilizationGO:007093580.058
leukocyte activationGO:00453211640.058
regulation of chemotaxisGO:0050920740.058
negative regulation of toll signaling pathwayGO:004575110.056
negative regulation of transferase activityGO:00513481240.056
Human
negative regulation of protein ubiquitinationGO:0031397350.055
regulation of interleukin 2 productionGO:0032663190.055
regulation of interleukin 6 biosynthetic processGO:004540850.055
myeloid leukocyte activationGO:0002274340.054
purine nucleotide catabolic processGO:00061954050.054
detection of triacyl bacterial lipopeptideGO:004249520.054
positive regulation of granulocyte chemotaxisGO:007162490.053
positive regulation of b cell proliferationGO:0030890120.053
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043140.053
positive regulation of cytokine mediated signaling pathwayGO:0001961120.053
positive regulation of interleukin 1 productionGO:0032732140.053
regulation of protein modification by small protein conjugation or removalGO:19033201070.053
antimicrobial humoral responseGO:0019730260.053
hematopoietic or lymphoid organ developmentGO:00485341860.052
response to oxygen levelsGO:00704821000.051
protein importGO:00170381300.051
interleukin 6 biosynthetic processGO:004222650.051
apoptotic signaling pathwayGO:00971902680.050
b cell activationGO:0042113330.049
embryonic epithelial tube formationGO:000183840.049
positive regulation of reactive oxygen species metabolic processGO:2000379240.049
myeloid dendritic cell activationGO:000177340.049
purine ribonucleoside metabolic processGO:00461284370.048
nitrogen compound transportGO:00717051910.048
myeloid cell differentiationGO:00300991170.047
regulation of mitotic cell cycle phase transitionGO:19019901180.046
regulation of response to external stimulusGO:00321012220.046
negative regulation of transportGO:00510511760.046
erk1 and erk2 cascadeGO:00703711040.046
regulation of bindingGO:00510981110.044
purine nucleoside monophosphate catabolic processGO:00091281580.044
amine metabolic processGO:0009308440.044
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.044
regulation of interleukin 1 productionGO:0032652210.043
regulation of alkaline phosphatase activityGO:001069220.043
positive regulation of nucleocytoplasmic transportGO:0046824540.042
regulation of chemokine productionGO:0032642310.042
myeloid dendritic cell differentiationGO:004301130.042
regulation of establishment of protein localizationGO:00702012420.041
positive regulation of purine nucleotide catabolic processGO:00331231850.041
regulation of tumor necrosis factor mediated signaling pathwayGO:0010803120.041
locomotory behaviorGO:000762610.041
cellular response to decreased oxygen levelsGO:0036294510.041
regulation of interleukin 1 mediated signaling pathwayGO:200065930.041
positive regulation of antimicrobial humoral responseGO:000276010.040
regulation of mononuclear cell proliferationGO:0032944650.040
establishment of endothelial barrierGO:0061028160.040
negative regulation of apoptotic processGO:00430663160.039
negative regulation of toll like receptor signaling pathwayGO:003412290.039
ribonucleotide catabolic processGO:00092614050.039
response to woundingGO:00096111680.038
tumor necrosis factor mediated signaling pathwayGO:0033209270.038
protein modification by small protein conjugationGO:00324463420.038
leukocyte migrationGO:00509001070.038
regulation of response to woundingGO:19030341010.037
regulation of multi organism processGO:00439001570.037
t helper 1 type immune responseGO:004208880.037
interleukin 8 productionGO:0032637510.036
wnt signaling pathwayGO:00160551560.036
multicellular organismal agingGO:001025930.036
type i interferon signaling pathwayGO:0060337110.035
regulation of cell divisionGO:00513021160.035
regulation of inflammatory responseGO:0050727460.034
negative regulation of cell deathGO:00605483450.034
negative regulation of toll like receptor 3 signaling pathwayGO:003414020.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
positive regulation of production of molecular mediator of immune responseGO:0002702110.032
regulation of intracellular transportGO:00323861950.032
regulation of antimicrobial humoral responseGO:000275910.032
positive regulation of locomotionGO:00400171860.032
response to exogenous dsrnaGO:0043330100.031
regulation of interferon beta productionGO:0032648220.031
cellular response to hypoxiaGO:0071456510.031
positive regulation of neutrophil migrationGO:190262470.030
cellular response to tumor necrosis factorGO:0071356630.030
cellular protein catabolic processGO:00442572610.030
regulation of erk1 and erk2 cascadeGO:0070372990.030
purine containing compound catabolic processGO:00725234110.029
purine ribonucleotide catabolic processGO:00091544040.029
adult locomotory behaviorGO:000834410.029
positive regulation of response to external stimulusGO:0032103880.029
cellular homeostasisGO:00197251960.029
neurotransmitter secretionGO:000726940.029
protein homooligomerizationGO:00512601000.029
regulation of nucleotide metabolic processGO:00061402690.028
positive regulation of cell migrationGO:00303351720.028
tube closureGO:006060630.028
regulation of type i interferon mediated signaling pathwayGO:006033890.028
anatomical structure homeostasisGO:00602491000.028
positive regulation of erk1 and erk2 cascadeGO:0070374750.027
cellular response to interleukin 1GO:0071347350.027
positive regulation of cell motilityGO:20001471770.027
endothelial cell developmentGO:0001885180.027
circadian behaviorGO:004851220.026
positive regulation of nucleotide metabolic processGO:00459812300.026
nucleotide catabolic processGO:00091664080.025
protein targetingGO:00066051870.025
nucleoside triphosphate catabolic processGO:00091433940.025
negative regulation of smooth muscle cell proliferationGO:0048662140.025
single organism cellular localizationGO:19025803320.025
regulation of b cell activationGO:0050864240.025
regulation of cholesterol effluxGO:0010874110.025
antigen processing and presentationGO:0019882330.024
intracellular receptor signaling pathwayGO:00305221040.024
regulation of protein complex disassemblyGO:0043244280.024
Human
neuromuscular junction developmentGO:000752830.024
atp metabolic processGO:00460341760.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
cellular response to mechanical stimulusGO:0071260390.024
regulation of protein localizationGO:00328802960.024
positive regulation of bindingGO:0051099450.024
positive regulation of b cell activationGO:0050871170.023
response to temperature stimulusGO:0009266220.023
purine ribonucleoside monophosphate catabolic processGO:00091691580.023
organonitrogen compound biosynthetic processGO:19015662000.023
glycosyl compound catabolic processGO:19016584130.022
response to mechanical stimulusGO:0009612510.022
regulation of b cell proliferationGO:0030888180.022
tube morphogenesisGO:0035239950.022
small molecule biosynthetic processGO:00442831570.022
positive regulation of leukocyte activationGO:0002696800.022
positive regulation of type i interferon mediated signaling pathwayGO:006034040.022
negative regulation of programmed cell deathGO:00430693210.022
cell cell signalingGO:00072671550.022
ribonucleoside monophosphate catabolic processGO:00091581580.022
regulation of mitosisGO:0007088630.022
nucleoside phosphate catabolic processGO:19012924120.022
female gamete generationGO:000729220.022
organic anion transportGO:00157111030.021
defense response to virusGO:0051607710.021
positive regulation of protein homodimerization activityGO:009007350.021
leukocyte chemotaxisGO:0030595760.021
positive regulation of tumor necrosis factor productionGO:0032760210.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
vasculature developmentGO:00019441810.021
regulation of cellular component movementGO:00512703340.021
negative regulation of cell proliferationGO:00082852280.021
positive regulation of leukocyte migrationGO:0002687460.021
regulation of interleukin 10 productionGO:0032653160.021
positive regulation of intracellular transportGO:00323881040.021
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.020
interleukin 2 productionGO:0032623200.020

IRAK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease by infectious agentDOID:0050117340.217
parasitic infectious diseaseDOID:1398160.217
cancerDOID:1621670.198
disease of cellular proliferationDOID:145661740.198
organ system cancerDOID:00506861640.136
musculoskeletal system diseaseDOID:172230.091
disease of metabolismDOID:00146672950.038
inherited metabolic disorderDOID:6552420.038
immune system cancerDOID:0060083360.031
integumentary system diseaseDOID:16430.030
skin diseaseDOID:37330.030
central nervous system diseaseDOID:3311860.030
nervous system diseaseDOID:8634310.030
hematologic cancerDOID:2531360.028
neurodegenerative diseaseDOID:12891020.021