Homo sapiens

47 known processes

WDR5

WD repeat domain 5

(Aliases: SWD3,BIG-3)

WDR5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin modificationGO:00165682981.000
chromatin organizationGO:00063253511.000
histone modificationGO:00165702511.000
protein alkylationGO:0008213741.000
covalent chromatin modificationGO:00165692541.000
histone methylationGO:0016571601.000
protein acetylationGO:00064731161.000
histone h3 k4 methylationGO:0051568271.000
histone h4 k8 acetylationGO:0043982151.000
histone lysine methylationGO:0034968501.000
protein methylationGO:0006479741.000
internal peptidyl lysine acetylationGO:0018393971.000
internal protein amino acid acetylationGO:00064751011.000
peptidyl lysine methylationGO:0018022371.000
peptidyl lysine acetylationGO:00183941011.000
protein acylationGO:00435431381.000
histone acetylationGO:0016573931.000
peptidyl lysine modificationGO:00182051441.000
histone h3 acetylationGO:0043966451.000
methylationGO:00322591061.000
macromolecule methylationGO:0043414970.999
cellular ketone metabolic processGO:0042180800.997
Mouse
cellular amino acid metabolic processGO:00065201160.995
peptidyl lysine dimethylationGO:001802730.992
histone h3 k4 trimethylationGO:008018270.991
histone h4 k5 acetylationGO:0043981150.986
histone h4 k16 acetylationGO:0043984140.983
amine metabolic processGO:0009308440.963
intracellular estrogen receptor signaling pathwayGO:0030520230.960
regulation of histone acetylationGO:0035065190.941
multicellular organismal agingGO:001025930.931
Worm
histone h4 acetylationGO:0043967470.923
regulation of histone modificationGO:0031056470.909
regulation of gene expression epigeneticGO:0040029730.881
response to estrogenGO:0043627470.858
positive regulation of cellular amino acid metabolic processGO:004576430.856
cell developmentGO:00484683280.843
Rat
regulation of cellular amino acid metabolic processGO:000652160.838
cell cycle checkpointGO:00000751170.817
Fly
regulation of chromatin organizationGO:1902275560.790
regulation of intracellular estrogen receptor signaling pathwayGO:0033146130.772
negative regulation of catalytic activityGO:00430863350.749
transdifferentiationGO:006029020.741
Worm
protein processingGO:00164852260.726
regulation of chromosome organizationGO:00330441030.707
regulation of chromatin modificationGO:1903308510.705
determination of adult lifespanGO:000834020.690
Worm
immune system developmentGO:00025201950.685
response to radiationGO:00093141510.681
regulation of peptidyl lysine acetylationGO:2000756220.675
chordate embryonic developmentGO:0043009340.670
regulation of cellular ketone metabolic processGO:0010565500.667
Mouse
cellular amine metabolic processGO:0044106410.663
hematopoietic or lymphoid organ developmentGO:00485341860.660
regulation of cellular amine metabolic processGO:0033238110.643
peptidyl lysine trimethylationGO:0018023100.629
chromatin silencingGO:0006342120.619
positive regulation of histone modificationGO:0031058290.614
dna repairGO:00062811980.596
positive regulation of cellular component organizationGO:00511303760.573
positive regulation of growthGO:0045927580.539
positive regulation of chromosome organizationGO:2001252410.539
response to organic cyclic compoundGO:00140702040.537
growthGO:00400072020.527
response to hormoneGO:00097251750.514
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.495
heart morphogenesisGO:0003007480.451
response to lipidGO:00339932060.444
dna conformation changeGO:00711031130.440
taxisGO:00423301570.434
single organism reproductive processGO:0044702980.426
Worm
nervous system developmentGO:00073992930.422
Rat Fly
protein stabilizationGO:0050821640.421
negative regulation of cell cycleGO:00457861930.417
Fly
female gamete generationGO:000729220.411
response to steroid hormoneGO:0048545800.410
compound eye developmentGO:004874910.400
positive regulation of chromatin modificationGO:1903310300.398
cellular component morphogenesisGO:00329893140.367
telomere organizationGO:0032200330.357
embryo developmentGO:00097901230.346
dna modificationGO:0006304270.332
erythrocyte developmentGO:004882130.327
regulation of cell cycleGO:00517263930.319
Fly
negative regulation of mitotic cell cycle phase transitionGO:1901991850.308
Fly
dna damage checkpointGO:0000077680.302
Fly
reproductive processGO:00224141060.296
Worm
gene silencingGO:0016458490.295
cell fate commitmentGO:0045165270.293
blastoderm segmentationGO:000735020.288
oogenesisGO:004847720.286
positive regulation of organelle organizationGO:00106381950.286
protein ubiquitinationGO:00165673140.282
gonad developmentGO:0008406340.267
Worm
hemopoiesisGO:00300971800.257
chromatin remodelingGO:0006338550.256
Fly
positive regulation of cell proliferationGO:00082843010.245
regulation of cell differentiationGO:00455953930.238
cardiovascular system developmentGO:00723582620.238
agingGO:0007568660.231
Worm
negative regulation of interleukin 2 productionGO:003270370.230
regulation of response to dna damage stimulusGO:2001020940.222
neuron projection developmentGO:00311751060.222
Rat
negative regulation of cellular protein metabolic processGO:00322693530.212
oocyte differentiationGO:000999420.212
regulation of protein acetylationGO:1901983250.202
negative regulation of proteolysisGO:00458611320.190
regulation of sequence specific dna binding transcription factor activityGO:00510902110.177
mitotic nuclear divisionGO:00070671190.173
regulation of histone h3 k4 methylationGO:0051569100.161
cellular response to abiotic stimulusGO:00712141170.158
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.158
protein modification by small protein conjugationGO:00324463420.155
segmentationGO:003528240.155
regulation of protein processingGO:00706131500.150
embryonic organ developmentGO:0048568360.138
chromatin mediated maintenance of transcriptionGO:004809620.137
cell morphogenesis involved in differentiationGO:00009041440.135
developmental growthGO:0048589480.132
development of primary sexual characteristicsGO:0045137350.129
Worm
cell projection morphogenesisGO:00488581290.128
oocyte developmentGO:004859910.127
positive regulation of endopeptidase activityGO:0010950840.126
chromatin assembly or disassemblyGO:0006333780.125
regulation of cell growthGO:00015581350.125
post embryonic developmentGO:000979120.125
Worm
cell part morphogenesisGO:00329901370.125
positive regulation of peptidase activityGO:0010952880.122
telomere maintenanceGO:0000723320.114
cellular response to dna damage stimulusGO:00069743790.113
Fly
regulation of cell divisionGO:00513021160.113
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.105
regulation of histone methylationGO:0031060160.102
blood vessel developmentGO:00015681720.102
mitotic cell cycle processGO:19030472860.102
Fly
cell projection organizationGO:00300302520.101
Rat
generation of neuronsGO:00486991520.101
Rat
cell morphogenesis involved in neuron differentiationGO:0048667440.100
negative regulation of cell cycle processGO:00109481210.100
Fly
negative regulation of gene expression epigeneticGO:0045814190.100
cellular protein catabolic processGO:00442572610.100
regulation of endopeptidase activityGO:00525481700.099
cell growthGO:00160491600.098
posttranscriptional regulation of gene expressionGO:00106082130.093
dna methylation or demethylationGO:0044728190.093
embryonic pattern specificationGO:000988050.088
positive regulation of gene expression epigeneticGO:004581570.087
negative regulation of apoptotic processGO:00430663160.085
central nervous system developmentGO:00074171230.085
neuron projection morphogenesisGO:0048812500.085
positive regulation of cell growthGO:0030307480.083
somatic stem cell maintenanceGO:003501940.083
regulation of wnt signaling pathwayGO:00301111230.080
reproductionGO:0000003630.079
Worm
regulation of peptidase activityGO:00525471800.079
negative regulation of protein metabolic processGO:00512483910.078
reproductive system developmentGO:0061458560.078
Worm
regulation of cysteine type endopeptidase activityGO:20001161270.076
positive regulation of cellular amine metabolic processGO:003324070.075
ribonucleoside monophosphate metabolic processGO:00091611870.074
anatomical structure homeostasisGO:00602491000.072
chemotaxisGO:00069351570.071
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.071
purine ribonucleoside triphosphate metabolic processGO:00092054110.069
regulation of cell cycle processGO:00105642660.069
Fly
regulation of osteoblast differentiationGO:0045667380.069
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.066
positive regulation of catabolic processGO:00098963100.063
positive regulation of programmed cell deathGO:00430682490.063
cell cycle phase transitionGO:00447701730.061
Fly
cell cell signalingGO:00072671550.061
regulation of growthGO:00400081650.060
regulation of protein ubiquitinationGO:0031396950.060
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.060
multi organism reproductive processGO:0044703540.059
neuron differentiationGO:00301821380.058
Rat
sex differentiationGO:0007548450.058
Worm
response to abiotic stimulusGO:00096283360.056
axon developmentGO:0061564340.056
response to ionizing radiationGO:0010212650.055
regulation of transcription from rna polymerase ii promoter in response to stressGO:0043618170.055
cellular response to radiationGO:0071478650.054
dna integrity checkpointGO:0031570710.052
Fly
negative regulation of transferase activityGO:00513481240.051
negative regulation of protein processingGO:00109551420.051
ncrna processingGO:0034470830.051
in utero embryonic developmentGO:000170180.051
positive regulation of proteolysisGO:00458621420.050
regulation of protein catabolic processGO:00421761550.050
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.049
chromosome segregationGO:00070591140.049
locomotory behaviorGO:000762610.048
multicellular organismal reproductive processGO:0048609400.048
regulation of cellular protein catabolic processGO:1903362960.047
neuron developmentGO:00486661130.047
Rat
axonogenesisGO:0007409310.044
protein maturationGO:00516042330.044
regulation of transporter activityGO:0032409820.043
positive regulation of dna templated transcription elongationGO:0032786180.042
regulation of proteolysisGO:00301622930.042
proteolysis involved in cellular protein catabolic processGO:00516032440.042
negative regulation of cellular component organizationGO:00511292350.041
multicellular organism reproductionGO:0032504420.041
dna packagingGO:0006323770.040
positive regulation of developmental processGO:00510943140.040
regulation of cellular response to stressGO:00801352440.039
regionalizationGO:0003002290.039
negative regulation of phosphorus metabolic processGO:00105632670.039
negative regulation of protein maturationGO:19033181420.039
regulation of dna metabolic processGO:00510521530.039
blastocyst developmentGO:000182430.037
response to other organismGO:00517072610.037
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.037
ribosome biogenesisGO:0042254480.036
regulation of protein stabilityGO:0031647870.036
modification dependent protein catabolic processGO:00199412090.035
protein catabolic processGO:00301633250.035
regulation of dna repairGO:0006282470.035
sister chromatid segregationGO:0000819540.035
double strand break repairGO:00063021010.034
organ growthGO:0035265120.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
developmental process involved in reproductionGO:0003006660.032
Worm
proteasomal protein catabolic processGO:00104981760.032
axon guidanceGO:0007411120.031
vasculature developmentGO:00019441810.031
palate developmentGO:0060021130.031
nucleotide catabolic processGO:00091664080.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
negative regulation of multicellular organismal processGO:00512413170.030
Worm
mitotic dna damage checkpointGO:0044773280.030
Fly
purine nucleoside monophosphate metabolic processGO:00091261860.030
ribosomal large subunit biogenesisGO:0042273100.030
negative regulation of stem cell differentiationGO:2000737220.029
inner ear morphogenesisGO:004247240.029
protein modification by small protein removalGO:0070646920.028
negative regulation of cell deathGO:00605483450.028
regulation of protein localizationGO:00328802960.028
positive regulation of protein catabolic processGO:0045732750.028
sensory organ developmentGO:0007423520.028
regulation of cellular component biogenesisGO:00440872810.027
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.027
dna replicationGO:00062601160.026
regulation of cell cycle phase transitionGO:19019871260.026
Fly
regulation of protein complex assemblyGO:00432541470.026
embryo development ending in birth or egg hatchingGO:0009792340.026
regulation of mitotic cell cycleGO:00073461890.026
Fly
reproductive structure developmentGO:0048608550.026
Worm
regulation of mitotic cell cycle phase transitionGO:19019901180.026
Fly
dna alkylationGO:000630570.026
regulation of transcription from rna polymerase i promoterGO:0006356100.026
nucleoside triphosphate metabolic processGO:00091414220.024
regulation of hormone levelsGO:00108171250.024
mitotic cell cycleGO:00002783260.024
Fly
protein monoubiquitinationGO:0006513390.024
regulation of organ growthGO:004662070.024
response to light stimulusGO:0009416870.024
positive regulation of histone h3 k9 methylationGO:005157430.024
cell divisionGO:00513011680.023
negative regulation of developmental processGO:00510932470.023
Worm
gamete generationGO:0007276250.023
ubiquitin dependent protein catabolic processGO:00065112060.023
wnt signaling pathwayGO:00160551560.022
cell morphogenesisGO:00009022960.022
ribonucleoside catabolic processGO:00424544060.022
positive regulation of hydrolase activityGO:00513453310.022
purine ribonucleoside monophosphate metabolic processGO:00091671860.022
protein localization to organelleGO:00333652800.021
interleukin 2 productionGO:0032623200.021
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.021
memoryGO:000761330.021
negative regulation of protein kinase activityGO:0006469980.020
regulation of cytoskeleton organizationGO:00514931770.019
regulation of protein bindingGO:0043393660.019
negative regulation of wnt signaling pathwayGO:0030178690.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
regulation of dna templated transcription in response to stressGO:0043620180.018
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314850.018
stress activated protein kinase signaling cascadeGO:0031098940.017
behaviorGO:00076101120.017
blood vessel morphogenesisGO:00485141620.017
head developmentGO:00603221080.017
single organism membrane organizationGO:00448022680.017
cellular response to organic cyclic compoundGO:00714071270.016
genitalia developmentGO:0048806100.016
regulation of dna biosynthetic processGO:2000278180.016
negative regulation of cellular protein catabolic processGO:1903363380.016
regulation of cytoplasmic transportGO:19036491490.016
histone arginine methylationGO:003496960.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
regulation of protein modification by small protein conjugation or removalGO:19033201070.016
immune responseGO:00069553070.016
regulation of protein maturationGO:19033171500.015
regulation of proteasomal protein catabolic processGO:0061136870.015
brain developmentGO:0007420970.015
cellular response to uvGO:0034644320.015
embryonic organ morphogenesisGO:0048562240.015
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.014
negative regulation of protein modification processGO:00314002000.014
regulation of growth hormone secretionGO:006012330.014
cellular process involved in reproduction in multicellular organismGO:0022412150.014
negative regulation of phosphorylationGO:00423261740.014
mrna metabolic processGO:00160711750.014
dendrite developmentGO:0016358240.014
skeletal system developmentGO:0001501790.014
Mouse
sexual reproductionGO:0019953370.014
neuron projection guidanceGO:0097485120.013
nucleoside triphosphate catabolic processGO:00091433940.013
negative regulation of programmed cell deathGO:00430693210.013
atp metabolic processGO:00460341760.013
nucleoside phosphate catabolic processGO:19012924120.013
regulation of dna replicationGO:0006275680.013
central nervous system neuron axonogenesisGO:002195530.012
negative regulation of hydrolase activityGO:00513461820.012
positive regulation of intracellular steroid hormone receptor signaling pathwayGO:003314570.012
signal releaseGO:0023061700.012
embryonic skeletal system morphogenesisGO:004870490.012
purine nucleoside catabolic processGO:00061523980.012
positive regulation of cell cycle processGO:00900681060.012
myeloid cell differentiationGO:00300991170.012
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:003609130.012
viral processGO:00160321460.011
negative regulation of cell differentiationGO:00455961710.011
positive regulation of cell deathGO:00109422630.011
artery morphogenesisGO:004884470.011
cellular response to transforming growth factor beta stimulusGO:0071560940.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
cytokine productionGO:00018162470.011
response to growth factorGO:00708482050.011
regulation of developmental growthGO:0048638300.010
ncrna metabolic processGO:00346601080.010
regulation of mitosisGO:0007088630.010

WDR5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cognitive disorderDOID:1561290.023
disease of mental healthDOID:150700.023
nervous system diseaseDOID:8634310.011
sensory system diseaseDOID:00501552030.011