Homo sapiens

137 known processes

INSIG1

insulin induced gene 1

(Aliases: CL6,CL-6,MGC1405)

INSIG1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
steroid metabolic processGO:0008202940.991
Mouse
lipid metabolic processGO:00066293810.980
Mouse
alcohol metabolic processGO:00060661140.953
Mouse
sterol metabolic processGO:0016125280.941
Mouse
lipid biosynthetic processGO:00086101770.909
Mouse
cholesterol metabolic processGO:0008203280.904
Mouse
sterol biosynthetic processGO:0016126100.885
Mouse
organic hydroxy compound metabolic processGO:19016151470.851
Mouse
response to phenylpropanoidGO:008018410.672
cellular lipid metabolic processGO:00442553030.642
Mouse
steroid biosynthetic processGO:0006694460.630
Mouse
small molecule biosynthetic processGO:00442831570.629
Mouse
positive regulation of cholesterol storageGO:001088640.594
organic hydroxy compound biosynthetic processGO:1901617710.504
Mouse
associative learningGO:000830610.402
organic hydroxy compound transportGO:0015850630.397
response to lipidGO:00339932060.393
monocarboxylic acid biosynthetic processGO:0072330670.393
Mouse
alcohol biosynthetic processGO:0046165520.368
Mouse
visual behaviorGO:000763220.314
negative regulation of map kinase activityGO:0043407270.308
acylglycerol metabolic processGO:0006639270.307
Mouse
response to abiotic stimulusGO:00096283360.276
cholesterol transportGO:0030301390.236
regulation of cholesterol homeostasisGO:200018820.228
cholesterol biosynthetic processGO:0006695100.228
Mouse
negative regulation of catalytic activityGO:00430863350.215
organophosphate biosynthetic processGO:00904071630.215
negative regulation of protein metabolic processGO:00512483910.199
terpenoid biosynthetic processGO:001611420.196
regulation of protein kinase activityGO:00458592890.182
vesicle mediated transportGO:00161923710.176
regulation of transferase activityGO:00513383550.166
cellular response to gonadotropin stimulusGO:007137140.157
post embryonic developmentGO:000979120.142
sterol transportGO:0015918390.135
determination of adult lifespanGO:000834020.128
response to light stimulusGO:0009416870.113
positive regulation of triglyceride biosynthetic processGO:001086740.106
growthGO:00400072020.104
regulation of protein serine threonine kinase activityGO:00719001790.103
negative regulation of growth of symbiont in hostGO:004413010.103
phosphatidylcholine catabolic processGO:003463830.099
growth of symbiont in hostGO:004411710.092
lipid localizationGO:00108761060.090
response to inorganic substanceGO:00100351270.086
positive regulation of lipid storageGO:0010884100.083
triglyceride metabolic processGO:0006641230.082
Mouse
terpenoid metabolic processGO:0006721270.080
chemical homeostasisGO:00488783060.080
multicellular organismal agingGO:001025930.078
maintenance of locationGO:00512351120.077
phospholipid metabolic processGO:0006644990.072
fatty acid elongation polyunsaturated fatty acidGO:003462640.069
response to nitrogen compoundGO:19016981840.067
neutral lipid metabolic processGO:0006638270.067
Mouse
head developmentGO:00603221080.067
amine metabolic processGO:0009308440.065
cholesterol homeostasisGO:0042632280.064
skin developmentGO:0043588760.062
negative regulation of cellular protein metabolic processGO:00322693530.052
regulation of kinase activityGO:00435493140.052
glycerolipid metabolic processGO:00464861070.051
Mouse
innate immune responseGO:00450871780.049
immune responseGO:00069553070.046
cellular alcohol metabolic processGO:004410770.046
defense responseGO:00069523150.044
cellular protein complex assemblyGO:00436231880.044
organophosphate catabolic processGO:00464344300.044
lipid storageGO:0019915280.042
response to hormoneGO:00097251750.042
response to radiationGO:00093141510.041
response to low density lipoprotein particleGO:005509840.041
glycerolipid biosynthetic processGO:0045017510.040
response to organonitrogen compoundGO:00102431560.038
cellular response to organic cyclic compoundGO:00714071270.038
negative regulation of kinase activityGO:00336731060.038
positive regulation of lipid biosynthetic processGO:0046889220.037
isoprenoid biosynthetic processGO:000829990.037
lipid transportGO:0006869900.037
regulation of cellular ketone metabolic processGO:0010565500.036
Mouse
sphingolipid metabolic processGO:0006665380.036
protein catabolic processGO:00301633250.036
regulation of cellular amino acid metabolic processGO:000652160.036
positive regulation of triglyceride metabolic processGO:009020890.035
response to drugGO:0042493810.034
immune system developmentGO:00025201950.034
phospholipid biosynthetic processGO:0008654440.034
negative regulation of phosphate metabolic processGO:00459362670.033
cellular macromolecule catabolic processGO:00442653800.033
cholesterol importGO:007050840.032
cellular amino acid metabolic processGO:00065201160.032
lipid catabolic processGO:0016042840.031
mapk cascadeGO:00001652880.031
response to oxygen levelsGO:00704821000.031
triglyceride biosynthetic processGO:0019432100.031
response to organic cyclic compoundGO:00140702040.030
response to lipoprotein particleGO:005509450.030
cellular lipid catabolic processGO:0044242650.030
cellular amine metabolic processGO:0044106410.030
mitotic cell cycle processGO:19030472860.029
protein oligomerizationGO:00512591730.029
regulation of cellular amine metabolic processGO:0033238110.029
phospholipid catabolic processGO:0009395120.029
isoprenoid metabolic processGO:0006720390.029
neutral lipid biosynthetic processGO:0046460110.028
regulation of lipid metabolic processGO:0019216960.028
Mouse
negative regulation of transferase activityGO:00513481240.028
response to oxygen containing compoundGO:19017003690.027
long chain fatty acid biosynthetic processGO:004275940.027
male sex differentiationGO:0046661250.027
negative regulation of protein processingGO:00109551420.027
cytoplasmic transportGO:00164823790.027
regulation of growthGO:00400081650.027
regulation of mapk cascadeGO:00434082620.027
small molecule catabolic processGO:0044282920.027
mitotic cell cycleGO:00002783260.026
embryo developmentGO:00097901230.026
Mouse
reproductive system developmentGO:0061458560.025
fatty acid metabolic processGO:00066311150.025
Mouse
cellular biogenic amine metabolic processGO:0006576340.024
positive regulation of catabolic processGO:00098963100.024
cellular alcohol biosynthetic processGO:004410870.024
anion transportGO:00068201610.024
signal transduction by phosphorylationGO:00230142970.023
endocytosisGO:00068971590.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
regulation of purine nucleotide metabolic processGO:19005422640.023
regulation of vesicle mediated transportGO:00606271300.023
negative regulation of transportGO:00510511760.023
cellular response to hormone stimulusGO:00328701250.023
neurotransmitter secretionGO:000726940.023
response to decreased oxygen levelsGO:0036293960.022
negative regulation of intracellular signal transductionGO:19025321830.022
negative regulation of protein serine threonine kinase activityGO:0071901570.022
regulation of protein localizationGO:00328802960.022
cytoskeleton dependent cytokinesisGO:0061640220.022
purine containing compound catabolic processGO:00725234110.022
regulation of lipid transport by regulation of transcription from rna polymerase ii promoterGO:007236740.022
regulation of purine nucleotide catabolic processGO:00331212050.022
system processGO:00030083490.022
response to alcoholGO:0097305640.022
nervous system developmentGO:00073992930.022
negative regulation of phosphorylationGO:00423261740.021
cellular response to lipidGO:00713961270.021
glycoprotein metabolic processGO:00091001100.021
regulation of homeostatic processGO:00328441210.021
lipoprotein metabolic processGO:0042157420.021
negative regulation of growth of symbiont involved in interaction with hostGO:004414620.021
regulation of nucleotide metabolic processGO:00061402690.020
negative regulation of protein phosphorylationGO:00019331400.020
neuromuscular junction developmentGO:000752830.020
negative regulation of protein modification processGO:00314002000.020
matingGO:000761810.020
negative regulation of cellular amine metabolic processGO:003323930.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
acylglycerol biosynthetic processGO:0046463110.019
negative regulation of cholesterol effluxGO:009037020.019
cholesterol effluxGO:0033344280.019
glycosyl compound catabolic processGO:19016584130.019
very long chain fatty acid biosynthetic processGO:004276170.019
cognitionGO:0050890430.019
dephosphorylationGO:00163112090.018
ras protein signal transductionGO:0007265730.018
membrane organizationGO:00610242920.018
response to nutrient levelsGO:0031667810.018
response to extracellular stimulusGO:0009991850.018
regulation of intracellular transportGO:00323861950.017
reproductive processGO:00224141060.017
ribonucleoside catabolic processGO:00424544060.017
reactive nitrogen species metabolic processGO:200105730.017
oogenesisGO:004847720.017
growth involved in symbiotic interactionGO:004411020.017
regulation of cell motilityGO:20001452990.017
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.017
regulation of cytoplasmic transportGO:19036491490.017
proteasomal protein catabolic processGO:00104981760.016
purine nucleotide catabolic processGO:00061954050.016
visual learningGO:000854210.016
response to external biotic stimulusGO:00432072610.016
glycoprotein transportGO:003443620.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
protein processingGO:00164852260.016
organic anion transportGO:00157111030.016
regulation of map kinase activityGO:00434051080.016
protein tetramerizationGO:0051262470.016
positive regulation of cell proliferationGO:00082843010.016
positive regulation of nucleotide metabolic processGO:00459812300.016
response to sterolGO:0036314140.016
ribonucleotide catabolic processGO:00092614050.016
actin filament based processGO:00300292240.016
rhythmic behaviorGO:000762220.015
myosin filament assemblyGO:003103420.015
regulation of establishment of protein localizationGO:00702012420.015
sex differentiationGO:0007548450.015
negative regulation of apoptotic processGO:00430663160.015
purine ribonucleoside metabolic processGO:00461284370.015
regulation of triglyceride metabolic processGO:0090207110.015
nucleocytoplasmic transportGO:00069131760.015
regulation of cell migrationGO:00303342890.015
regulation of protein maturationGO:19033171500.015
cellular protein catabolic processGO:00442572610.015
positive regulation of secretionGO:00510471160.015
cellular macromolecular complex assemblyGO:00346223240.015
alcohol catabolic processGO:0046164200.015
regulation of lipid transportGO:0032368440.015
protein targetingGO:00066051870.015
cardiovascular system developmentGO:00723582620.015
positive regulation of intracellular transportGO:00323881040.014
lipoprotein catabolic processGO:004215910.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
negative regulation of programmed cell deathGO:00430693210.014
response to steroid hormoneGO:0048545800.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
response to other organismGO:00517072610.014
apoptotic signaling pathwayGO:00971902680.014
negative regulation of protein kinase activityGO:0006469980.014
blastoderm segmentationGO:000735020.014
cellular response to nitrogen compoundGO:19016991440.014
hindbrain developmentGO:003090230.014
regulation of response to external stimulusGO:00321012220.014
ion homeostasisGO:00508012300.014
cellular response to endogenous stimulusGO:00714953360.014
regulation of proteolysisGO:00301622930.014
transmembrane transportGO:00550853990.014
positive regulation of golgi to plasma membrane protein transportGO:004299820.014
establishment of protein localization to organelleGO:00725941720.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
adult locomotory behaviorGO:000834410.014
anterior posterior axis specificationGO:000994820.014
single organism cellular localizationGO:19025803320.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
intracellular protein transportGO:00068862700.014
regulation of protein localization to plasma membraneGO:1903076400.014
nucleoside phosphate catabolic processGO:19012924120.013
nuclear transportGO:00511691790.013
positive regulation of developmental processGO:00510943140.013
cellular homeostasisGO:00197251960.013
nucleoside catabolic processGO:00091644080.013
regulation of cell cycleGO:00517263930.013
nerve developmentGO:002167540.013
receptor mediated endocytosisGO:0006898840.013
endomembrane system organizationGO:00102561960.013
poly n acetyllactosamine metabolic processGO:003030920.013
rho protein signal transductionGO:0007266260.013
cellular metal ion homeostasisGO:00068751460.013
central nervous system developmentGO:00074171230.013
positive regulation of nucleotide catabolic processGO:00308131850.013
carbohydrate metabolic processGO:00059752070.013
regulation of anatomical structure morphogenesisGO:00226032860.013
multicellular organismal response to stressGO:003355510.013
photoreceptor cell differentiationGO:004653020.013
regulation of immune responseGO:00507762010.013
positive regulation of programmed cell deathGO:00430682490.013
morphogenesis of embryonic epitheliumGO:001633140.013
cation transmembrane transportGO:00986552380.013
peripheral nervous system developmentGO:000742220.013
sensory perception of smellGO:000760820.013
establishment of tissue polarityGO:000716430.013
sequestering of calcium ionGO:0051208170.013
regulation of triglyceride biosynthetic processGO:001086650.013
purine nucleoside catabolic processGO:00061523980.013
cellular response to oxygen containing compoundGO:19017012760.012
ubiquitin dependent protein catabolic processGO:00065112060.012
fat cell differentiationGO:0045444320.012
Mouse
spermatid differentiationGO:004851540.012
glycosylationGO:0070085710.012
response to metal ionGO:0010038840.012
regulation of cell differentiationGO:00455953930.012
Mouse
protein homooligomerizationGO:00512601000.012
modification dependent protein catabolic processGO:00199412090.012
rab protein signal transductionGO:003248240.012
positive regulation of nucleoside metabolic processGO:00459791860.012
agingGO:0007568660.012
regulation of nucleoside metabolic processGO:00091182090.012
nuclear importGO:00511701060.012
modulation of growth of symbiont involved in interaction with hostGO:004414420.012
negative regulation of proteolysisGO:00458611320.012
nucleotide catabolic processGO:00091664080.012
ribonucleoside triphosphate catabolic processGO:00092033910.012
response to sucroseGO:000974410.012
oocyte developmentGO:004859910.012
response to fungusGO:000962040.012
phospholipid transportGO:0015914230.012
microtubule based processGO:00070172100.012
response to purine containing compoundGO:0014074400.012
negative regulation of multicellular organismal processGO:00512413170.012
negative regulation of endopeptidase activityGO:0010951840.012
cell morphogenesisGO:00009022960.012
motor neuron axon guidanceGO:000804520.012
reactive oxygen species metabolic processGO:0072593750.012
negative regulation of hydrolase activityGO:00513461820.012
response to nutrientGO:0007584200.012
regulation of cholesterol storageGO:001088580.012
intestinal cholesterol absorptionGO:003029940.012
positive regulation of cellular component organizationGO:00511303760.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
cellular response to organonitrogen compoundGO:00714171240.012
reactive oxygen species biosynthetic processGO:190340940.012
protein localization to plasma membraneGO:0072659930.012
regulation of defense responseGO:00313471540.012
behaviorGO:00076101120.011
spinal cord developmentGO:002151040.011
nucleoside triphosphate catabolic processGO:00091433940.011
cell developmentGO:00484683280.011
protein localization to organelleGO:00333652800.011
response to peptide hormoneGO:0043434610.011
sulfur compound biosynthetic processGO:0044272380.011
segmentationGO:003528240.011
regulation of synaptic plasticityGO:004816730.011
carboxylic acid biosynthetic processGO:0046394970.011
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of multi organism processGO:00439001570.011
regulation of growth of symbiont in hostGO:004412610.011
positive regulation of lipid metabolic processGO:0045834500.011
nucleoside triphosphate metabolic processGO:00091414220.011
regenerationGO:003109940.011
fatty acid elongation saturated fatty acidGO:001936750.011
metal ion transportGO:00300012720.011
regulation of cytokine productionGO:00018172320.011
regulation of cellular component biogenesisGO:00440872810.011
neurological system processGO:00508771630.011
morphogenesis of a polarized epitheliumGO:000173830.011
protein importGO:00170381300.011
inner ear morphogenesisGO:004247240.011
Mouse
striated muscle myosin thick filament assemblyGO:007168820.011
neuroblast proliferationGO:000740540.011
positive regulation of phosphorylationGO:00423273940.011
guanosine containing compound catabolic processGO:19010692390.011
regulation of protein transportGO:00512232130.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
cellular response to sterolGO:003631570.011
memoryGO:000761330.011
interspecies interaction between organismsGO:00444191560.011
single organism behaviorGO:0044708280.011
cell fate determinationGO:000170930.011
purine nucleoside triphosphate metabolic processGO:00091444120.011
negative regulation of catabolic processGO:00098951040.011
cellular response to cytokine stimulusGO:00713451810.011
spermatid developmentGO:000728640.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
sex determinationGO:000753030.011
purine ribonucleoside catabolic processGO:00461303980.011
peptide transportGO:0015833740.010
taxisGO:00423301570.010
atp metabolic processGO:00460341760.010
behavioral response to ethanolGO:004814920.010
cerebellum developmentGO:002154920.010
response to axon injuryGO:004867810.010
cation homeostasisGO:00550801890.010
forebrain generation of neuronsGO:002187230.010

INSIG1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
lipid metabolism disorderDOID:3146260.124
inherited metabolic disorderDOID:6552420.124
disease of metabolismDOID:00146672950.124
disease of cellular proliferationDOID:145661740.024
familial hyperlipidemiaDOID:116890.015
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.015
cancerDOID:1621670.015
retinal diseaseDOID:56791180.012
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
immune system diseaseDOID:29141550.012
myopathyDOID:4231040.010
muscular diseaseDOID:00800001140.010
muscle tissue diseaseDOID:661130.010
musculoskeletal system diseaseDOID:172230.010