Homo sapiens

34 known processes

KDM2B

lysine (K)-specific demethylase 2B

(Aliases: JHDM1B,CXXC2,Fbl10,PCCX2,FBXL10)

KDM2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of odontogenesisGO:004248140.802
regulation of tooth mineralizationGO:007017030.545
protein alkylationGO:0008213740.544
histone h2a ubiquitinationGO:0033522170.310
regulation of ossificationGO:0030278580.300
protein modification by small protein conjugationGO:00324463420.288
protein methylationGO:0006479740.277
regulation of bone mineralizationGO:0030500290.267
protein ubiquitinationGO:00165673140.255
histone ubiquitinationGO:0016574310.230
chromatin organizationGO:00063253510.226
covalent chromatin modificationGO:00165692540.221
histone h3 k4 methylationGO:0051568270.218
negative regulation of protein metabolic processGO:00512483910.209
bone mineralizationGO:0030282340.201
macromolecule methylationGO:0043414970.197
negative regulation of cellular component organizationGO:00511292350.196
chromatin modificationGO:00165682980.184
protein monoubiquitinationGO:0006513390.182
ossificationGO:00015031210.177
histone modificationGO:00165702510.176
biomineral tissue developmentGO:0031214390.173
negative regulation of chromosome organizationGO:2001251480.171
negative regulation of organelle organizationGO:00106391260.165
regulation of biomineral tissue developmentGO:0070167310.163
negative regulation of bone mineralizationGO:003050270.154
negative regulation of chromatin modificationGO:1903309210.147
methylationGO:00322591060.145
circulatory system developmentGO:00723592620.143
specification of axis polarityGO:006500110.136
negative regulation of developmental processGO:00510932470.134
negative regulation of biomineral tissue developmentGO:007016880.116
negative regulation of cellular protein metabolic processGO:00322693530.100
cardiovascular system developmentGO:00723582620.097
negative regulation of protein modification processGO:00314002000.096
regulation of chromatin modificationGO:1903308510.088
regulation of chromatin organizationGO:1902275560.078
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.077
Mouse
regulation of anatomical structure morphogenesisGO:00226032860.077
regulation of organ morphogenesisGO:2000027240.072
regulation of chromosome organizationGO:00330441030.071
organ morphogenesisGO:00098871470.070
Mouse
negative regulation of histone modificationGO:0031057190.067
cellular macromolecule catabolic processGO:00442653800.066
cellular protein catabolic processGO:00442572610.063
protein catabolic processGO:00301633250.059
regulation of histone modificationGO:0031056470.058
mitotic cell cycleGO:00002783260.057
Human
cellular amine metabolic processGO:0044106410.056
modification dependent protein catabolic processGO:00199412090.056
multicellular organismal agingGO:001025930.055
Worm
cellular amino acid metabolic processGO:00065201160.055
regulation of cellular amine metabolic processGO:0033238110.055
amine metabolic processGO:0009308440.054
proteasomal protein catabolic processGO:00104981760.053
negative regulation of ossificationGO:0030279210.051
regulation of cellular amino acid metabolic processGO:000652160.050
palate developmentGO:0060021130.049
modification dependent macromolecule catabolic processGO:00436322120.048
proteolysis involved in cellular protein catabolic processGO:00516032440.047
ubiquitin dependent protein catabolic processGO:00065112060.047
regulation of nucleotide metabolic processGO:00061402690.046
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.044
female gamete generationGO:000729220.044
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:0031146150.043
regulation of histone methylationGO:0031060160.041
purine nucleoside triphosphate metabolic processGO:00091444120.041
odontogenesisGO:0042476250.040
locomotory behaviorGO:000762610.040
regulation of transferase activityGO:00513383550.039
mitotic cell cycle processGO:19030472860.039
Human
cellular ketone metabolic processGO:0042180800.039
guanosine containing compound metabolic processGO:19010682440.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
positive regulation of cellular amine metabolic processGO:003324070.038
purine containing compound catabolic processGO:00725234110.037
regulation of cellular ketone metabolic processGO:0010565500.036
glycosyl compound catabolic processGO:19016584130.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
post embryonic developmentGO:000979120.035
positive regulation of transferase activityGO:00513472270.034
mitotic cell cycle phase transitionGO:00447721620.034
Human
small gtpase mediated signal transductionGO:0007264780.034
purine ribonucleoside metabolic processGO:00461284370.034
anterior posterior axis specificationGO:000994820.034
regulation of purine nucleotide metabolic processGO:19005422640.033
heart developmentGO:0007507950.033
purine ribonucleotide catabolic processGO:00091544040.033
determination of adult lifespanGO:000834020.032
Worm
purine nucleotide catabolic processGO:00061954050.032
cellular response to dna damage stimulusGO:00069743790.031
ras protein signal transductionGO:0007265730.031
positive regulation of nucleotide metabolic processGO:00459812300.031
negative regulation of multicellular organismal processGO:00512413170.031
nucleoside triphosphate catabolic processGO:00091433940.030
regulation of cell cycleGO:00517263930.030
neuromuscular junction developmentGO:000752830.030
cytoplasmic transportGO:00164823790.030
hemopoiesisGO:00300971800.030
organophosphate catabolic processGO:00464344300.029
nucleoside triphosphate metabolic processGO:00091414220.029
regulation of nucleotide catabolic processGO:00308112050.029
nucleoside catabolic processGO:00091644080.029
immune responseGO:00069553070.029
nucleotide catabolic processGO:00091664080.029
ribonucleotide catabolic processGO:00092614050.029
oocyte differentiationGO:000999420.029
purine nucleoside catabolic processGO:00061523980.028
cation transportGO:00068123310.028
positive regulation of cellular catabolic processGO:00313312840.028
negative regulation of cell deathGO:00605483450.027
Mouse
negative regulation of cell cycle processGO:00109481210.027
protein localization to organelleGO:00333652800.027
metal ion transportGO:00300012720.027
oogenesisGO:004847720.027
regulation of cytoskeleton organizationGO:00514931770.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
positive regulation of phosphorylationGO:00423273940.027
cell morphogenesisGO:00009022960.027
chemical homeostasisGO:00488783060.027
hematopoietic or lymphoid organ developmentGO:00485341860.027
microtubule cytoskeleton organizationGO:00002261760.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
negative regulation of catalytic activityGO:00430863350.026
regulation of nucleoside metabolic processGO:00091182090.026
positive regulation of cellular component organizationGO:00511303760.026
regulation of histone h3 k4 methylationGO:0051569100.025
regulation of cell cycle processGO:00105642660.025
positive regulation of catabolic processGO:00098963100.025
blastoderm segmentationGO:000735020.025
cellular macromolecular complex assemblyGO:00346223240.025
regulation of mitotic cell cycle phase transitionGO:19019901180.025
nervous system developmentGO:00073992930.025
Mouse
regulation of purine nucleotide catabolic processGO:00331212050.024
cellular component morphogenesisGO:00329893140.024
gtp catabolic processGO:00061842370.024
positive regulation of hydrolase activityGO:00513453310.023
gtp metabolic processGO:00460392390.023
nucleoside phosphate catabolic processGO:19012924120.023
ion transmembrane transportGO:00342203380.023
positive regulation of cell deathGO:00109422630.023
positive regulation of immune system processGO:00026842830.023
negative regulation of phosphate metabolic processGO:00459362670.023
purine ribonucleoside catabolic processGO:00461303980.023
negative regulation of programmed cell deathGO:00430693210.023
Mouse
regulation of protein catabolic processGO:00421761550.023
cell adhesionGO:00071553250.023
morphogenesis of embryonic epitheliumGO:001633140.022
Mouse
actin filament based processGO:00300292240.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
histone h3 k36 methylationGO:001045250.022
transmembrane transportGO:00550853990.022
response to oxygen containing compoundGO:19017003690.022
regulation of proteolysisGO:00301622930.021
regulation of mapk cascadeGO:00434082620.021
system processGO:00030083490.021
defense responseGO:00069523150.021
oocyte developmentGO:004859910.021
positive regulation of transportGO:00510503360.021
signal transduction by phosphorylationGO:00230142970.021
ribonucleoside catabolic processGO:00424544060.021
regulation of cell differentiationGO:00455953930.021
regulation of gtpase activityGO:00430871800.020
regulation of kinase activityGO:00435493140.020
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.020
nitrogen compound transportGO:00717051910.020
circadian behaviorGO:004851220.020
lipid metabolic processGO:00066293810.020
regulation of mitotic cell cycleGO:00073461890.020
cardiac muscle cell contractionGO:008600340.020
apoptotic signaling pathwayGO:00971902680.019
regulation of protein kinase activityGO:00458592890.019
ion homeostasisGO:00508012300.019
maintenance of locationGO:00512351120.019
negative regulation of phosphorus metabolic processGO:00105632670.019
biological adhesionGO:00226103310.019
cellular protein complex assemblyGO:00436231880.019
vesicle mediated transportGO:00161923710.019
Worm
regulation of protein localizationGO:00328802960.019
cation homeostasisGO:00550801890.018
adult locomotory behaviorGO:000834410.018
tooth mineralizationGO:003450560.018
endomembrane system organizationGO:00102561960.018
rho protein signal transductionGO:0007266260.018
regulation of microtubule based processGO:0032886740.018
single organism membrane organizationGO:00448022680.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
cell cycle phase transitionGO:00447701730.018
Human
inorganic ion transmembrane transportGO:00986602310.018
regulation of microtubule cytoskeleton organizationGO:0070507610.018
intracellular protein transportGO:00068862700.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
response to abiotic stimulusGO:00096283360.018
regulation of cellular component movementGO:00512703340.018
regulation of cellular response to stressGO:00801352440.017
negative regulation of mitotic cell cycleGO:00459301020.017
response to inorganic substanceGO:00100351270.017
inorganic cation transmembrane transportGO:00986621940.017
regulation of cellular component biogenesisGO:00440872810.017
cation transmembrane transportGO:00986552380.017
positive regulation of nucleotide catabolic processGO:00308131850.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
positive regulation of kinase activityGO:00336742040.017
compound eye developmentGO:004874910.017
innate immune responseGO:00450871780.017
regulation of gtp catabolic processGO:00331241800.017
regulation of cell cycle phase transitionGO:19019871260.016
regulation of immune responseGO:00507762010.016
negative regulation of cell cycle phase transitionGO:1901988890.016
cellular homeostasisGO:00197251960.016
regenerationGO:003109940.016
organonitrogen compound biosynthetic processGO:19015662000.016
response to external biotic stimulusGO:00432072610.016
single organism carbohydrate metabolic processGO:00447231930.016
rna interferenceGO:001624640.016
response to biotic stimulusGO:00096072760.016
negative regulation of cell cycleGO:00457861930.016
histone acetylationGO:0016573930.016
anion transportGO:00068201610.016
single organism cellular localizationGO:19025803320.016
cellular chemical homeostasisGO:00550821800.016
regulation of cell developmentGO:00602841610.016
associative learningGO:000830610.016
guanosine containing compound catabolic processGO:19010692390.016
hindbrain developmentGO:003090230.016
Mouse
neurogenesisGO:00220081690.016
internal protein amino acid acetylationGO:00064751010.015
mitotic nuclear divisionGO:00070671190.015
growthGO:00400072020.015
mapk cascadeGO:00001652880.015
microtubule based processGO:00070172100.015
protein maturationGO:00516042330.015
memoryGO:000761330.015
regulation of secretionGO:00510461940.015
cell projection organizationGO:00300302520.015
blood vessel morphogenesisGO:00485141620.015
dna packagingGO:0006323770.015
cellular response to oxygen containing compoundGO:19017012760.015
negative regulation of protein maturationGO:19033181420.015
organelle assemblyGO:00709251760.015
carbohydrate metabolic processGO:00059752070.015
positive regulation of protein phosphorylationGO:00019343130.015
spermatid differentiationGO:004851540.015
response to fungusGO:000962040.015
protein processingGO:00164852260.015
dephosphorylationGO:00163112090.015
protein acylationGO:00435431380.014
spermatid developmentGO:000728640.014
regulation of cell motilityGO:20001452990.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
regulation of response to external stimulusGO:00321012220.014
organelle fissionGO:00482851490.014
cell divisionGO:00513011680.014
positive regulation of cell proliferationGO:00082843010.014
positive regulation of immune responseGO:00507781590.014
regulation of protein processingGO:00706131500.014
regulation of secretion by cellGO:19035301770.014
secretionGO:00469032540.014
positive regulation of nucleoside metabolic processGO:00459791860.014
cellular response to endogenous stimulusGO:00714953360.014
posttranscriptional regulation of gene expressionGO:00106082130.014
primary neural tube formationGO:001402030.014
Mouse
secretion by cellGO:00329402260.014
histone lysine methylationGO:0034968500.014
striated muscle contractionGO:0006941520.014
carbohydrate derivative biosynthetic processGO:19011372070.014
membrane organizationGO:00610242920.014
Worm
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
wnt signaling pathwayGO:00160551560.014
segmentationGO:003528240.014
Fly
negative regulation of cellular amino acid metabolic processGO:004576320.014
histone methylationGO:0016571600.014
cellular cation homeostasisGO:00300031630.014
central nervous system developmentGO:00074171230.014
Mouse
regulation of locomotionGO:00400123290.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
blood vessel developmentGO:00015681720.014
actin cytoskeleton organizationGO:00300362070.013
negative regulation of protein processingGO:00109551420.013
nuclear divisionGO:00002801280.013
divalent metal ion transportGO:00708381520.013
response to nitrogen compoundGO:19016981840.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.013
positive regulation of programmed cell deathGO:00430682490.013
regulation of cell morphogenesisGO:00226041530.013
positive regulation of apoptotic processGO:00430652460.013
regulation of multi organism processGO:00439001570.013
regulation of cytokine productionGO:00018172320.013
cell activationGO:00017752130.013
neuron developmentGO:00486661130.013
peptidyl lysine acetylationGO:00183941010.013
negative regulation of hydrolase activityGO:00513461820.013
cell part morphogenesisGO:00329901370.013
defense response to fungusGO:005083240.013
protein targetingGO:00066051870.013
positive regulation of gtp catabolic processGO:00331261660.013
tripartite regional subdivisionGO:000735120.013
anterior posterior axis specification embryoGO:000859520.013
peptidyl lysine modificationGO:00182051440.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.013
regulation of neural precursor cell proliferationGO:200017740.013
Mouse
neural tube formationGO:000184130.013
Mouse
positive regulation of mapk cascadeGO:00434101900.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of cell migrationGO:00303342890.013
negative regulation of cellular amine metabolic processGO:003323930.013
cytokine productionGO:00018162470.013
cellular ion homeostasisGO:00068731680.013
anatomical structure formation involved in morphogenesisGO:00486462840.012
Mouse
negative regulation of proteolysisGO:00458611320.012
vasculature developmentGO:00019441810.012
regulation of growthGO:00400081650.012
response to radiationGO:00093141510.012
nucleocytoplasmic transportGO:00069131760.012
positive regulation of synaptic transmissionGO:005080640.012
stem cell divisionGO:001714520.012
thymus developmentGO:004853830.012
regulation of protein serine threonine kinase activityGO:00719001790.012
divalent inorganic cation transportGO:00725111580.012
sulfur compound metabolic processGO:00067901010.012
positive regulation of protein kinase activityGO:00458601900.012
cerebral cortex radially oriented cell migrationGO:002179910.012
positive regulation of organelle organizationGO:00106381950.012
lens development in camera type eyeGO:000208820.012
cellular lipid metabolic processGO:00442553030.012
lipid transportGO:0006869900.012
negative regulation of transportGO:00510511760.012
protein localization to nucleusGO:00345041360.012
lipid localizationGO:00108761060.012
rhythmic behaviorGO:000762220.012
positive regulation of protein ubiquitinationGO:0031398530.012
oxidation reduction processGO:00551143960.012
Human
dna conformation changeGO:00711031130.012
regulation of cell activationGO:00508651250.012
actin mediated cell contractionGO:0070252120.012
epithelium developmentGO:00604292270.012
Mouse
response to other organismGO:00517072610.012
peptidyl tyrosine phosphorylationGO:00181081700.012
regulation of dna metabolic processGO:00510521530.012
peptidyl tyrosine modificationGO:00182121700.012
developmental programmed cell deathGO:001062330.012
positive regulation of cellular component biogenesisGO:00440891580.012
dna repairGO:00062811980.012
i kappab kinase nf kappab signalingGO:00072491660.012
regulation of ras gtpase activityGO:00323181280.012
negative regulation of cell proliferationGO:00082852280.012
Mouse
response to hormoneGO:00097251750.012
protein oligomerizationGO:00512591730.012
regulation of protein maturationGO:19033171500.012
metal ion homeostasisGO:00550651690.012
blastocyst developmentGO:000182430.012
organic anion transportGO:00157111030.012
microtubule organizing center organizationGO:0031023620.012
establishment of nucleus localizationGO:004002310.012
matingGO:000761810.012
regulation of leukocyte activationGO:00026941150.012
response to axon injuryGO:004867810.012
regulation of cell adhesionGO:00301551660.012
cardiac muscle contractionGO:0060048340.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
chemotaxisGO:00069351570.011
reproductive processGO:00224141060.011
Mouse
cerebellum developmentGO:002154920.011
negative regulation of phosphorylationGO:00423261740.011
atp metabolic processGO:00460341760.011
angiogenesisGO:00015251470.011
pharynx developmentGO:006046510.011
regulation of establishment of protein localizationGO:00702012420.011
establishment of protein localization to organelleGO:00725941720.011
amide transportGO:0042886760.011
regulation of meiotic cell cycleGO:005144540.011
cerebral cortex cell migrationGO:002179530.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
photoreceptor cell differentiationGO:004653020.011
nucleus localizationGO:005164710.011
nerve developmentGO:002167540.011
regulation of cytoplasmic transportGO:19036491490.011
response to activityGO:001482300.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
organophosphate biosynthetic processGO:00904071630.011
regulation of cell projection organizationGO:00313441070.011
cellular response to oxidative stressGO:0034599850.011
positive regulation of gtpase activityGO:00435471660.011
embryonic epithelial tube formationGO:000183840.011
Mouse
limbic system developmentGO:002176130.011
regulation of cell divisionGO:00513021160.011
nucleoside monophosphate metabolic processGO:00091231910.011
leukocyte activationGO:00453211640.011
sequestering of metal ionGO:0051238240.011
mrna metabolic processGO:00160711750.011
negative regulation of cellular catabolic processGO:0031330830.011
divalent inorganic cation homeostasisGO:00725071360.011
regulation of cellular protein catabolic processGO:1903362960.011
regulation of cell growthGO:00015581350.011
defense response to other organismGO:00985421290.011
inner ear morphogenesisGO:004247240.011
cell cycle checkpointGO:00000751170.011
peripheral nervous system developmentGO:000742220.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of actin filament based processGO:00329701410.011
negative regulation of intracellular signal transductionGO:19025321830.011
negative regulation of immune system processGO:00026831360.011
calcium ion transportGO:00068161470.011
motor neuron axon guidanceGO:000804520.011
neurotransmitter secretionGO:000726940.010
activation of immune responseGO:00022531140.010
monovalent inorganic cation transportGO:00156721280.010
regulation of protein transportGO:00512232130.010
negative regulation of cell differentiationGO:00455961710.010
regulation of lymphocyte activationGO:00512491030.010
regulation of gene expression epigeneticGO:0040029730.010
Human
regulation of vesicle mediated transportGO:00606271300.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of intracellular transportGO:00323861950.010
cell projection morphogenesisGO:00488581290.010
regulation of ion transportGO:00432691890.010
actin filament based movementGO:0030048170.010
male genitalia developmentGO:003053910.010
negative regulation of catabolic processGO:00098951040.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
response to organic cyclic compoundGO:00140702040.010
cellular response to abiotic stimulusGO:00712141170.010
regulation of glial cell proliferationGO:006025140.010
neurological system processGO:00508771630.010
meiotic chromosome segregationGO:004513240.010
morphogenesis of a polarized epitheliumGO:000173830.010
muscle contractionGO:0006936730.010
negative regulation of gliogenesisGO:001401430.010
positive regulation of cell cycle processGO:00900681060.010
negative regulation of transferase activityGO:00513481240.010

KDM2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.847
nervous system diseaseDOID:8634310.847
eye and adnexa diseaseDOID:14921500.847
eye diseaseDOID:56141490.824
microphthalmiaDOID:10629110.211
central nervous system diseaseDOID:3311860.026
musculoskeletal system diseaseDOID:172230.021
neurodegenerative diseaseDOID:12891020.019
disease of metabolismDOID:00146672950.013
disease of mental healthDOID:150700.012
connective tissue diseaseDOID:651090.012
disease of cellular proliferationDOID:145661740.012
organ system cancerDOID:00506861640.012
cancerDOID:1621670.012
immune system diseaseDOID:29141550.011
bone diseaseDOID:0080001880.011