Homo sapiens

54 known processes

KLHL25

kelch-like 25 (Drosophila)

(Aliases: ENC-2,FLJ12587,FLJ45015,ENC2)

KLHL25 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.060
rho protein signal transductionGO:0007266260.058
cellular amino acid metabolic processGO:00065201160.041
regulation of cellular amine metabolic processGO:0033238110.041
cellular ketone metabolic processGO:0042180800.040
actin filament based processGO:00300292240.039
glycosyl compound catabolic processGO:19016584130.039
regulation of cellular amino acid metabolic processGO:000652160.039
small gtpase mediated signal transductionGO:0007264780.038
oogenesisGO:004847720.038
multicellular organismal agingGO:001025930.037
amine metabolic processGO:0009308440.036
ribonucleoside catabolic processGO:00424544060.036
female gamete generationGO:000729220.035
ras protein signal transductionGO:0007265730.034
nucleoside triphosphate metabolic processGO:00091414220.034
cation transportGO:00068123310.034
Human
cellular amine metabolic processGO:0044106410.034
positive regulation of cellular amino acid metabolic processGO:004576430.033
membrane organizationGO:00610242920.032
Human
regulation of cell cycleGO:00517263930.032
Human
single organism membrane organizationGO:00448022680.031
Human
purine ribonucleoside metabolic processGO:00461284370.031
segmentationGO:003528240.031
determination of adult lifespanGO:000834020.031
nucleoside catabolic processGO:00091644080.031
purine ribonucleoside catabolic processGO:00461303980.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
positive regulation of phosphorylationGO:00423273940.030
regulation of cellular ketone metabolic processGO:0010565500.030
purine containing compound catabolic processGO:00725234110.029
nucleoside phosphate catabolic processGO:19012924120.029
organophosphate catabolic processGO:00464344300.029
ribonucleoside triphosphate catabolic processGO:00092033910.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
purine nucleoside triphosphate metabolic processGO:00091444120.028
purine ribonucleotide catabolic processGO:00091544040.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
positive regulation of cellular amine metabolic processGO:003324070.028
nucleotide catabolic processGO:00091664080.028
purine nucleotide catabolic processGO:00061954050.027
nucleoside triphosphate catabolic processGO:00091433940.027
cardiac muscle cell contractionGO:008600340.027
endomembrane system organizationGO:00102561960.027
cellular macromolecule catabolic processGO:00442653800.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
positive regulation of cellular component organizationGO:00511303760.026
gtp metabolic processGO:00460392390.026
purine nucleoside catabolic processGO:00061523980.026
single organism cellular localizationGO:19025803320.026
Human
cell adhesionGO:00071553250.026
regulation of cellular component biogenesisGO:00440872810.026
nerve developmentGO:002167540.025
regulation of cell differentiationGO:00455953930.025
cellular response to dna damage stimulusGO:00069743790.025
guanosine containing compound catabolic processGO:19010692390.025
neuromuscular junction developmentGO:000752830.025
negative regulation of protein metabolic processGO:00512483910.025
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.024
mitotic cell cycleGO:00002783260.024
regulation of protein transportGO:00512232130.024
regulation of cell cycle processGO:00105642660.024
Human
transmembrane transportGO:00550853990.024
negative regulation of cellular protein metabolic processGO:00322693530.024
Human
protein maturationGO:00516042330.023
ribonucleotide catabolic processGO:00092614050.023
cell morphogenesisGO:00009022960.023
cellular component morphogenesisGO:00329893140.023
biological adhesionGO:00226103310.023
regulation of protein localizationGO:00328802960.023
regulation of anatomical structure morphogenesisGO:00226032860.022
regulation of nucleoside metabolic processGO:00091182090.022
negative regulation of phosphorus metabolic processGO:00105632670.022
positive regulation of hydrolase activityGO:00513453310.022
response to abiotic stimulusGO:00096283360.022
regulation of kinase activityGO:00435493140.022
negative regulation of catalytic activityGO:00430863350.022
negative regulation of developmental processGO:00510932470.022
gtp catabolic processGO:00061842370.022
regulation of cellular response to stressGO:00801352440.022
protein processingGO:00164852260.022
cell projection organizationGO:00300302520.021
regenerationGO:003109940.021
mitotic cell cycle processGO:19030472860.021
positive regulation of catabolic processGO:00098963100.021
guanosine containing compound metabolic processGO:19010682440.021
immune responseGO:00069553070.021
positive regulation of protein phosphorylationGO:00019343130.021
blastoderm segmentationGO:000735020.021
locomotory behaviorGO:000762610.021
regulation of transferase activityGO:00513383550.021
cation transmembrane transportGO:00986552380.021
cellular protein catabolic processGO:00442572610.021
positive regulation of cellular catabolic processGO:00313312840.021
protein modification by small protein conjugationGO:00324463420.021
actin cytoskeleton organizationGO:00300362070.021
inorganic ion transmembrane transportGO:00986602310.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
apoptotic signaling pathwayGO:00971902680.020
cytoplasmic transportGO:00164823790.020
Human
negative regulation of phosphate metabolic processGO:00459362670.020
positive regulation of nucleotide metabolic processGO:00459812300.020
cell developmentGO:00484683280.020
carbohydrate derivative biosynthetic processGO:19011372070.020
regulation of nucleotide metabolic processGO:00061402690.020
positive regulation of developmental processGO:00510943140.020
positive regulation of gtpase activityGO:00435471660.020
protein localization to organelleGO:00333652800.020
Human
system processGO:00030083490.019
Human
protein catabolic processGO:00301633250.019
morphogenesis of embryonic epitheliumGO:001633140.019
anterior posterior axis specificationGO:000994820.019
cell divisionGO:00513011680.019
Human
oocyte developmentGO:004859910.019
rhythmic behaviorGO:000762220.019
protein ubiquitinationGO:00165673140.019
cellular macromolecular complex assemblyGO:00346223240.019
establishment of protein localization to membraneGO:00901501210.019
cell growthGO:00160491600.018
intracellular protein transportGO:00068862700.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
regulation of cytoskeleton organizationGO:00514931770.018
plasma membrane organizationGO:00070091150.018
signal transduction by phosphorylationGO:00230142970.018
regulation of gtpase activityGO:00430871800.018
regulation of establishment of protein localizationGO:00702012420.018
motor neuron axon guidanceGO:000804520.018
oocyte differentiationGO:000999420.018
cellular response to endogenous stimulusGO:00714953360.018
nervous system developmentGO:00073992930.018
regulation of nucleotide catabolic processGO:00308112050.018
striated muscle contractionGO:0006941520.018
positive regulation of nucleoside metabolic processGO:00459791860.018
epithelium developmentGO:00604292270.018
Human
protein localization to membraneGO:00726571600.018
peripheral nervous system developmentGO:000742220.018
somatic stem cell maintenanceGO:003501940.018
dephosphorylationGO:00163112090.017
circadian behaviorGO:004851220.017
visual behaviorGO:000763220.017
cranial nerve developmentGO:002154540.017
opioid receptor signaling pathwayGO:003800340.017
negative regulation of programmed cell deathGO:00430693210.017
Human
positive regulation of cell deathGO:00109422630.017
vesicle mediated transportGO:00161923710.017
Human
regulation of actin filament based processGO:00329701410.017
microtubule based processGO:00070172100.017
memoryGO:000761330.017
histone modificationGO:00165702510.017
spermatid differentiationGO:004851540.017
regulation of proteolysisGO:00301622930.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
wnt signaling pathwayGO:00160551560.017
Human
regulation of cell growthGO:00015581350.017
cardiovascular system developmentGO:00723582620.017
inner ear morphogenesisGO:004247240.017
blood vessel developmentGO:00015681720.017
modification dependent protein catabolic processGO:00199412090.017
regulation of response to external stimulusGO:00321012220.017
regulation of protein kinase activityGO:00458592890.017
carbohydrate metabolic processGO:00059752070.016
cellular protein complex assemblyGO:00436231880.016
blood vessel morphogenesisGO:00485141620.016
negative regulation of multicellular organismal processGO:00512413170.016
positive regulation of gtp catabolic processGO:00331261660.016
positive regulation of nucleotide catabolic processGO:00308131850.016
actin filament based movementGO:0030048170.016
response to oxygen containing compoundGO:19017003690.016
regulation of purine nucleotide catabolic processGO:00331212050.016
modification dependent macromolecule catabolic processGO:00436322120.016
cell cycle phase transitionGO:00447701730.016
negative regulation of cellular amine metabolic processGO:003323930.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of cellular component movementGO:00512703340.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
retinal ganglion cell axon guidanceGO:003129020.016
regulation of locomotionGO:00400123290.016
adult locomotory behaviorGO:000834410.016
negative regulation of apoptotic processGO:00430663160.016
Human
tripartite regional subdivisionGO:000735120.016
negative regulation of protein modification processGO:00314002000.016
ubiquitin dependent protein catabolic processGO:00065112060.016
salivary gland morphogenesisGO:000743540.016
cellular lipid metabolic processGO:00442553030.016
reactive oxygen species biosynthetic processGO:190340940.016
lipid metabolic processGO:00066293810.016
epithelial cell differentiationGO:00308551410.016
ion transmembrane transportGO:00342203380.016
posttranscriptional regulation of gene expressionGO:00106082130.016
protein targetingGO:00066051870.016
positive regulation of immune system processGO:00026842830.015
single organism carbohydrate metabolic processGO:00447231930.015
positive regulation of transportGO:00510503360.015
regulation of ras gtpase activityGO:00323181280.015
anterior posterior axis specification embryoGO:000859520.015
regulation of cytokine productionGO:00018172320.015
regulation of purine nucleotide metabolic processGO:19005422640.015
positive regulation of cellular component biogenesisGO:00440891580.015
sulfur compound metabolic processGO:00067901010.015
defense responseGO:00069523150.015
mitochondrion organizationGO:00070051560.015
associative learningGO:000830610.015
photoreceptor cell differentiationGO:004653020.015
compound eye developmentGO:004874910.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
covalent chromatin modificationGO:00165692540.015
epidermis morphogenesisGO:004873030.015
negative regulation of cell deathGO:00605483450.015
Human
actin mediated cell contractionGO:0070252120.015
neurogenesisGO:00220081690.015
cdc42 protein signal transductionGO:003248840.014
dna repairGO:00062811980.014
establishment of protein localization to organelleGO:00725941720.014
mitotic cell cycle phase transitionGO:00447721620.014
monovalent inorganic cation transportGO:00156721280.014
Human
regulation of cell motilityGO:20001452990.014
mapk cascadeGO:00001652880.014
rna processingGO:00063962550.014
spermatid developmentGO:000728640.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of cell migrationGO:00303342890.014
protein localization to plasma membraneGO:0072659930.014
reactive nitrogen species metabolic processGO:200105730.014
negative regulation of phosphorylationGO:00423261740.014
hindbrain developmentGO:003090230.014
response to external biotic stimulusGO:00432072610.014
negative regulation of cell proliferationGO:00082852280.014
oxidation reduction processGO:00551143960.014
regulation of apoptotic signaling pathwayGO:20012331750.014
neuroblast proliferationGO:000740540.014
regulation of mapk cascadeGO:00434082620.014
cytokine productionGO:00018162470.014
establishment or maintenance of bipolar cell polarityGO:006124520.014
nitrogen compound transportGO:00717051910.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
positive regulation of organelle organizationGO:00106381950.014
chromatin organizationGO:00063253510.014
negative regulation of intracellular signal transductionGO:19025321830.014
positive regulation of transferase activityGO:00513472270.014
regulation of mitotic cell cycleGO:00073461890.014
negative regulation of cellular component organizationGO:00511292350.014
anion transportGO:00068201610.014
tissue morphogenesisGO:0048729960.014
Human
vasculature developmentGO:00019441810.014
organelle assemblyGO:00709251760.014
regulation of cell morphogenesisGO:00226041530.014
regulation of cell adhesionGO:00301551660.014
regulation of protein complex assemblyGO:00432541470.014
proteasomal protein catabolic processGO:00104981760.014
Human
microtubule cytoskeleton organizationGO:00002261760.014
regulation of gtp catabolic processGO:00331241800.014
embryonic epithelial tube formationGO:000183840.014
innate immune responseGO:00450871780.014
cellular response to cytokine stimulusGO:00713451810.014
regulation of meiotic cell cycleGO:005144540.014
chromatin modificationGO:00165682980.014
negative regulation of smoothened signaling pathwayGO:004587930.014
spinal cord developmentGO:002151040.014
circulatory system developmentGO:00723592620.013
regulation of ras protein signal transductionGO:00465781550.013
negative regulation of cell cycleGO:00457861930.013
multi organism cellular processGO:00447641560.013
cellular homeostasisGO:00197251960.013
cell substrate adhesionGO:00315891320.013
cell fate determinationGO:000170930.013
glycoprotein metabolic processGO:00091001100.013
sex determinationGO:000753030.013
cell matrix adhesionGO:0007160850.013
regulation of immune responseGO:00507762010.013
positive regulation of programmed cell deathGO:00430682490.013
endosomal transportGO:00161971290.013
Human
response to axon injuryGO:004867810.013
negative regulation of transferase activityGO:00513481240.013
positive regulation of apoptotic processGO:00430652460.013
positive regulation of cell proliferationGO:00082843010.013
regulation of protein processingGO:00706131500.013
taxisGO:00423301570.013
cell projection morphogenesisGO:00488581290.013
regulation of multi organism processGO:00439001570.013
response to cytokineGO:00340972320.013
melanin metabolic processGO:000658210.013
stem cell divisionGO:001714520.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
maintenance of locationGO:00512351120.013
cell morphogenesis involved in differentiationGO:00009041440.013
positive regulation of ras gtpase activityGO:00323201170.013
growthGO:00400072020.013
regulation of protein maturationGO:19033171500.012
regulation of neural precursor cell proliferationGO:200017740.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
engulfment of apoptotic cellGO:004365220.012
nucleocytoplasmic transportGO:00069131760.012
sleepGO:003043120.012
positive regulation of cell cycleGO:00457871400.012
cell part morphogenesisGO:00329901370.012
metencephalon developmentGO:002203720.012
regulation of rho protein signal transductionGO:0035023790.012
positive regulation of kinase activityGO:00336742040.012
response to fungusGO:000962040.012
pituitary gland developmentGO:002198320.012
cellular response to oxygen containing compoundGO:19017012760.012
neuron differentiationGO:00301821380.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
embryonic forelimb morphogenesisGO:003511540.012
response to growth factorGO:00708482050.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of intracellular transportGO:00323861950.012
reactive oxygen species metabolic processGO:0072593750.012
response to radiationGO:00093141510.012
muscle cell fate commitmentGO:004269340.012
regulation of ion transmembrane transportGO:00347651320.012
mrna metabolic processGO:00160711750.012
generation of neuronsGO:00486991520.012
regulation of rho gtpase activityGO:0032319660.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
Human
asymmetric stem cell divisionGO:009872210.012
protein oligomerizationGO:00512591730.012
positive regulation of cell cycle processGO:00900681060.012
cell projection assemblyGO:00300311260.012
regulation of axon guidanceGO:190266730.012
somatic stem cell divisionGO:004810310.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
nuclear transportGO:00511691790.012
small molecule biosynthetic processGO:00442831570.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
somitogenesisGO:000175620.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
angiogenesisGO:00015251470.012
meiotic chromosome segregationGO:004513240.011
regulation of large conductance calcium activated potassium channel activityGO:190260620.011
actin filament organizationGO:00070151280.011
i kappab kinase nf kappab signalingGO:00072491660.011
embryonic camera type eye developmentGO:003107620.011
protein modification by small protein removalGO:0070646920.011
keratinizationGO:003142420.011
regulation of growthGO:00400081650.011
tissue regenerationGO:004224630.011
regulation of transmembrane transportGO:00347621390.011
limbic system developmentGO:002176130.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
regulation of actin cytoskeleton organizationGO:00329561160.011
regulation of cell cycle phase transitionGO:19019871260.011
peptidyl serine phosphorylationGO:00181051010.011
negative regulation of cell growthGO:0030308830.011
matingGO:000761810.011
metal ion transportGO:00300012720.011
Human
positive regulation of cell differentiationGO:00455972110.011
regulation of protein catabolic processGO:00421761550.011
negative regulation of axonogenesisGO:005077140.011
secretion by cellGO:00329402260.011
meiosis iGO:000712740.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
neural tube formationGO:000184130.011
thymus developmentGO:004853830.011
cytokinesisGO:0000910960.011
Human
neuron fate commitmentGO:004866320.011
positive regulation of cell motilityGO:20001471770.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
response to biotic stimulusGO:00096072760.011
neuron projection regenerationGO:003110210.011
interspecies interaction between organismsGO:00444191560.011
myosin filament assemblyGO:003103420.011
rna splicingGO:00083801310.011
organ morphogenesisGO:00098871470.011
Human
neuron developmentGO:00486661130.011
regulation of protein stabilityGO:0031647870.011
negative regulation of organelle organizationGO:00106391260.011
peptidyl serine modificationGO:00182091060.011
organ formationGO:004864530.011
myoblast fusionGO:000752010.011
cell junction organizationGO:0034330790.011
negative regulation of growthGO:0045926970.011
positive regulation of aldosterone biosynthetic processGO:003234920.011
cell fate commitment involved in pattern specificationGO:006058110.011
neuron projection developmentGO:00311751060.011
single organism cell adhesionGO:00986021790.010
regulation of synaptic plasticityGO:004816730.010
establishment of protein localization to plasma membraneGO:0090002680.010
negative regulation of protein processingGO:00109551420.010
cannabinoid signaling pathwayGO:003817120.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
regulation of membrane potentialGO:0042391950.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
regulation of glial cell differentiationGO:004568530.010
negative regulation of male gonad developmentGO:200001910.010
regulation of endopeptidase activityGO:00525481700.010
stress activated mapk cascadeGO:0051403930.010
glial cell migrationGO:000834740.010
methylationGO:00322591060.010
regulation of wnt signaling pathwayGO:00301111230.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
viral processGO:00160321460.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
establishment of tissue polarityGO:000716430.010
midgut developmentGO:000749410.010
positive regulation of cellular component movementGO:00512721810.010
protein autophosphorylationGO:00467771230.010
tube closureGO:006060630.010
immune system developmentGO:00025201950.010
nucleoside monophosphate metabolic processGO:00091231910.010
negative regulation of proteolysisGO:00458611320.010
negative regulation of transportGO:00510511760.010
positive regulation of protein transportGO:00512221350.010
cell cell junction organizationGO:0045216690.010
negative regulation of protein maturationGO:19033181420.010
negative regulation of protein phosphorylationGO:00019331400.010
positive regulation of mapk cascadeGO:00434101900.010
regulation of meiosisGO:004002030.010
stress activated protein kinase signaling cascadeGO:0031098940.010
peptidyl tyrosine modificationGO:00182121700.010
intracellular mrna localizationGO:000829810.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of dephosphorylationGO:0035303960.010
defense response to fungusGO:005083240.010
small molecule catabolic processGO:0044282920.010
positive regulation of vascular endothelial growth factor signaling pathwayGO:190074830.010

KLHL25 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.031
sensory system diseaseDOID:00501552030.031
eye and adnexa diseaseDOID:14921500.026
eye diseaseDOID:56141490.026
musculoskeletal system diseaseDOID:172230.021
disease of metabolismDOID:00146672950.019
inherited metabolic disorderDOID:6552420.018
central nervous system diseaseDOID:3311860.017
retinal diseaseDOID:56791180.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
connective tissue diseaseDOID:651090.012
neurodegenerative diseaseDOID:12891020.012
retinal degenerationDOID:8466890.012
bone diseaseDOID:0080001880.012
muscular diseaseDOID:00800001140.010