Homo sapiens

90 known processes

POLQ

polymerase (DNA directed), theta

(Aliases: DKFZp781A0112,PRO0327,POLH)

POLQ biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ribonucleoside catabolic processGO:00424544060.323
ribonucleoside triphosphate catabolic processGO:00092033910.318
ribonucleoside monophosphate metabolic processGO:00091611870.221
cellular response to dna damage stimulusGO:00069743790.206
Human Mouse Fly
chromosome segregationGO:00070591140.206
nucleotide catabolic processGO:00091664080.181
post embryonic developmentGO:000979120.173
nucleoside triphosphate metabolic processGO:00091414220.170
purine ribonucleoside metabolic processGO:00461284370.166
nucleoside monophosphate metabolic processGO:00091231910.166
nucleoside phosphate catabolic processGO:19012924120.155
mitotic cell cycleGO:00002783260.148
nucleoside triphosphate catabolic processGO:00091433940.140
purine nucleoside monophosphate catabolic processGO:00091281580.139
regulation of cell cycleGO:00517263930.139
purine ribonucleotide catabolic processGO:00091544040.138
purine nucleoside catabolic processGO:00061523980.137
purine ribonucleoside catabolic processGO:00461303980.132
dna dependent dna replicationGO:0006261440.130
purine ribonucleoside monophosphate catabolic processGO:00091691580.127
chromatin modificationGO:00165682980.126
organophosphate catabolic processGO:00464344300.124
nuclear divisionGO:00002801280.119
cell divisionGO:00513011680.118
purine nucleoside monophosphate metabolic processGO:00091261860.118
dna replicationGO:00062601160.116
atp catabolic processGO:00062001570.112
purine nucleoside triphosphate metabolic processGO:00091444120.110
purine ribonucleoside triphosphate metabolic processGO:00092054110.103
meiotic chromosome segregationGO:004513240.090
nucleoside catabolic processGO:00091644080.089
purine nucleotide catabolic processGO:00061954050.088
purine containing compound catabolic processGO:00725234110.087
atp metabolic processGO:00460341760.085
mitotic nuclear divisionGO:00070671190.080
regulation of mitotic cell cycleGO:00073461890.076
nucleoside monophosphate catabolic processGO:00091251590.075
ribonucleoside monophosphate catabolic processGO:00091581580.075
ribonucleoside triphosphate metabolic processGO:00091994120.075
ribonucleotide catabolic processGO:00092614050.074
purine ribonucleoside triphosphate catabolic processGO:00092073910.074
dna recombinationGO:0006310770.068
Human
cellular ketone metabolic processGO:0042180800.067
regulation of kinase activityGO:00435493140.063
organelle fissionGO:00482851490.062
regulation of cell cycle processGO:00105642660.062
cellular macromolecule catabolic processGO:00442653800.060
anatomical structure homeostasisGO:00602491000.060
mitotic cell cycle processGO:19030472860.059
positive regulation of protein kinase activityGO:00458601900.056
purine ribonucleoside monophosphate metabolic processGO:00091671860.055
regulation of cell divisionGO:00513021160.052
positive regulation of cell proliferationGO:00082843010.051
double strand break repairGO:00063021010.049
Human Fly
dna repairGO:00062811980.049
Human Mouse Fly
positive regulation of catabolic processGO:00098963100.047
regulation of cellular ketone metabolic processGO:0010565500.046
mitotic cell cycle phase transitionGO:00447721620.046
positive regulation of kinase activityGO:00336742040.046
dna catabolic processGO:0006308490.045
female gamete generationGO:000729220.044
cell cycle phase transitionGO:00447701730.042
microtubule based processGO:00070172100.042
cellular amine metabolic processGO:0044106410.042
glycosyl compound catabolic processGO:19016584130.042
negative regulation of cell cycleGO:00457861930.041
positive regulation of phosphorylationGO:00423273940.040
male meiosisGO:000714010.039
immune responseGO:00069553070.038
regulation of protein kinase activityGO:00458592890.038
positive regulation of organelle organizationGO:00106381950.038
cell cycle checkpointGO:00000751170.038
regulation of cell cycle phase transitionGO:19019871260.037
meiotic nuclear divisionGO:0007126100.036
purine nucleoside triphosphate catabolic processGO:00091463920.035
negative regulation of programmed cell deathGO:00430693210.035
meiosis iGO:000712740.035
positive regulation of mitotic cell cycleGO:0045931600.034
organelle assemblyGO:00709251760.034
sister chromatid segregationGO:0000819540.034
regulation of cellular component biogenesisGO:00440872810.033
cellular component morphogenesisGO:00329893140.033
regulation of transferase activityGO:00513383550.032
cell developmentGO:00484683280.032
ubiquitin dependent protein catabolic processGO:00065112060.032
regulation of dna replicationGO:0006275680.031
neuroblast divisionGO:005505710.031
protein catabolic processGO:00301633250.030
primary neural tube formationGO:001402030.030
positive regulation of protein phosphorylationGO:00019343130.030
cerebral cortex cell migrationGO:002179530.028
cellular amino acid metabolic processGO:00065201160.028
regulation of purine nucleotide metabolic processGO:19005422640.028
telomere maintenanceGO:0000723320.028
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.028
regulation of cellular amine metabolic processGO:0033238110.027
morphogenesis of embryonic epitheliumGO:001633140.027
positive regulation of cellular catabolic processGO:00313312840.027
recombinational repairGO:0000725500.027
Human
negative regulation of cell cycle phase transitionGO:1901988890.026
chromatin organizationGO:00063253510.026
negative regulation of developmental processGO:00510932470.026
tube closureGO:006060630.026
positive regulation of cellular amine metabolic processGO:003324070.026
dna geometric changeGO:0032392320.025
positive regulation of cellular amino acid metabolic processGO:004576430.024
maintenance of locationGO:00512351120.024
regulation of protein serine threonine kinase activityGO:00719001790.024
cellular macromolecular complex assemblyGO:00346223240.024
regulation of proteolysisGO:00301622930.023
positive regulation of nucleoside metabolic processGO:00459791860.023
determination of adult lifespanGO:000834020.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
positive regulation of hydrolase activityGO:00513453310.023
chromatin assembly or disassemblyGO:0006333780.022
positive regulation of nucleotide metabolic processGO:00459812300.022
positive regulation of cell cycleGO:00457871400.022
regulation of chromosome segregationGO:0051983440.022
regulation of mitotic sister chromatid segregationGO:0033047270.022
positive regulation of dna metabolic processGO:0051054730.022
cell activationGO:00017752130.022
protein localization to organelleGO:00333652800.022
cell cycle g2 m phase transitionGO:0044839430.021
regulation of cellular amino acid metabolic processGO:000652160.021
negative regulation of cellular protein metabolic processGO:00322693530.021
amine metabolic processGO:0009308440.021
neural tube closureGO:000184330.021
negative regulation of cell cycle processGO:00109481210.021
vesicle mediated transportGO:00161923710.020
cell morphogenesisGO:00009022960.020
meiotic cell cycleGO:0051321130.020
regenerationGO:003109940.020
negative regulation of cellular component organizationGO:00511292350.020
leukocyte activationGO:00453211640.019
negative regulation of phosphate metabolic processGO:00459362670.019
regulation of nucleoside metabolic processGO:00091182090.019
negative regulation of mitotic cell cycleGO:00459301020.019
cellular protein catabolic processGO:00442572610.019
positive regulation of nucleotide catabolic processGO:00308131850.019
apoptotic signaling pathwayGO:00971902680.019
dephosphorylationGO:00163112090.019
negative regulation of cell sizeGO:004579230.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
lymphocyte activationGO:00466491330.018
sister chromatid biorientationGO:003113420.018
actin filament based processGO:00300292240.018
spermatid developmentGO:000728640.018
mitotic sister chromatid segregationGO:0000070530.018
negative regulation of catalytic activityGO:00430863350.018
regulation of cell morphogenesisGO:00226041530.018
g2 m transition of mitotic cell cycleGO:0000086410.017
mitotic cell cycle checkpointGO:0007093680.017
response to abiotic stimulusGO:00096283360.017
embryonic epithelial tube formationGO:000183840.017
regulation of anatomical structure morphogenesisGO:00226032860.017
regulation of dna metabolic processGO:00510521530.017
chemical homeostasisGO:00488783060.017
regulation of protein catabolic processGO:00421761550.017
cellular homeostasisGO:00197251960.016
maintenance of location in cellGO:0051651620.016
mitotic sister chromatid separationGO:0051306180.016
regulation of protein complex assemblyGO:00432541470.016
regulation of protein processingGO:00706131500.015
biological adhesionGO:00226103310.015
regulation of protein maturationGO:19033171500.015
regulation of nucleotide metabolic processGO:00061402690.015
positive regulation of programmed cell deathGO:00430682490.015
neural tube formationGO:000184130.015
regulation of proteasomal protein catabolic processGO:0061136870.015
reproductionGO:0000003630.015
negative regulation of apoptotic processGO:00430663160.015
regulation of purine nucleotide catabolic processGO:00331212050.015
double strand break repair via homologous recombinationGO:0000724500.015
Human
cell fate determinationGO:000170930.014
dna conformation changeGO:00711031130.014
negative regulation of protein maturationGO:19033181420.014
regulation of nucleotide catabolic processGO:00308112050.014
protein maturationGO:00516042330.014
negative regulation of phosphorus metabolic processGO:00105632670.014
regulation of bindingGO:00510981110.014
positive regulation of cell cycle processGO:00900681060.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
intracellular protein transportGO:00068862700.014
positive regulation of meiotic cell cycleGO:005144620.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
negative regulation of cell deathGO:00605483450.014
spermatid differentiationGO:004851540.014
dna duplex unwindingGO:0032508300.014
reproductive processGO:00224141060.014
forebrain generation of neuronsGO:002187230.013
protein dna complex subunit organizationGO:0071824800.013
blastocyst developmentGO:000182430.013
protein ubiquitinationGO:00165673140.013
cellular chemical homeostasisGO:00550821800.013
cytoplasmic transportGO:00164823790.013
oocyte developmentGO:004859910.013
regulation of establishment of protein localizationGO:00702012420.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
protein modification by small protein conjugationGO:00324463420.012
positive regulation of developmental processGO:00510943140.012
head developmentGO:00603221080.012
positive regulation of apoptotic processGO:00430652460.012
regulation of cytoskeleton organizationGO:00514931770.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
immune effector processGO:00022521590.012
cell projection organizationGO:00300302520.012
cellular protein complex assemblyGO:00436231880.012
protein targetingGO:00066051870.012
establishment of nucleus localizationGO:004002310.012
peptidyl lysine modificationGO:00182051440.012
negative regulation of hydrolase activityGO:00513461820.012
negative regulation of protein metabolic processGO:00512483910.012
oocyte differentiationGO:000999420.012
peripheral nervous system developmentGO:000742220.012
positive regulation of cellular component organizationGO:00511303760.012
regulation of cell differentiationGO:00455953930.012
cell activation involved in immune responseGO:0002263300.011
actin filament based movementGO:0030048170.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of chromosome organizationGO:00330441030.011
neuronal stem cell divisionGO:003644510.011
centrosome organizationGO:0051297580.011
modification dependent protein catabolic processGO:00199412090.011
negative regulation of multicellular organismal processGO:00512413170.011
cellular lipid metabolic processGO:00442553030.011
negative regulation of cellular protein catabolic processGO:1903363380.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
negative regulation of mitotic cell cycle phase transitionGO:1901991850.011
cell adhesionGO:00071553250.011
proteasomal protein catabolic processGO:00104981760.011
negative regulation of intracellular signal transductionGO:19025321830.011
single organism cellular localizationGO:19025803320.011
regulation of anatomical structure sizeGO:00900661010.011
negative regulation of methylation dependent chromatin silencingGO:009031020.011
actin cytoskeleton organizationGO:00300362070.011
guanosine containing compound catabolic processGO:19010692390.011
negative regulation of catabolic processGO:00098951040.011
single organism reproductive processGO:0044702980.010
oogenesisGO:004847720.010
cell part morphogenesisGO:00329901370.010
centrosome cycleGO:0007098320.010
rna splicingGO:00083801310.010
embryo developmentGO:00097901230.010
telomere organizationGO:0032200330.010
nervous system developmentGO:00073992930.010
positive regulation of proteolysisGO:00458621420.010
dna catabolic process exonucleolyticGO:0000738170.010
peptidyl tyrosine modificationGO:00182121700.010
gtp catabolic processGO:00061842370.010
regulation of dephosphorylationGO:0035303960.010
growthGO:00400072020.010

POLQ disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.059
cancerDOID:1621670.059
immune system diseaseDOID:29141550.031
hematopoietic system diseaseDOID:741000.031
organ system cancerDOID:00506861640.029
thoracic cancerDOID:5093210.025
breast cancerDOID:1612210.025
physical disorderDOID:0080015410.021
congenital nervous system abnormalityDOID:2490210.021