Homo sapiens

2 known processes

FH

fumarate hydratase

(Aliases: MCUL1,MCL,LRCC,HLRCC)

FH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.954
tricarboxylic acid cycleGO:000609940.706
post embryonic developmentGO:000979120.672
Worm
vesicle mediated transportGO:00161923710.529
Worm
determination of adult lifespanGO:000834020.490
dicarboxylic acid metabolic processGO:0043648290.474
multicellular organismal agingGO:001025930.445
coenzyme metabolic processGO:0006732650.331
positive regulation of peptidase activityGO:0010952880.319
cellular respirationGO:0045333210.264
cofactor metabolic processGO:0051186870.251
energy derivation by oxidation of organic compoundsGO:0015980430.228
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.224
citrate metabolic processGO:000610120.213
apoptotic mitochondrial changesGO:0008637570.204
positive regulation of cysteine type endopeptidase activityGO:2001056790.186
response to oxygen containing compoundGO:19017003690.176
protein maturationGO:00516042330.172
zymogen activationGO:0031638700.171
sulfur compound metabolic processGO:00067901010.169
regulation of peptidase activityGO:00525471800.164
protein processingGO:00164852260.161
carbohydrate derivative biosynthetic processGO:19011372070.160
nucleotide biosynthetic processGO:00091651090.158
monocarboxylic acid metabolic processGO:00327871850.152
nucleoside phosphate biosynthetic processGO:19012931090.152
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.151
positive regulation of apoptotic processGO:00430652460.141
regulation of endopeptidase activityGO:00525481700.141
cofactor biosynthetic processGO:0051188310.138
cellular amino acid metabolic processGO:00065201160.137
embryo developmentGO:00097901230.128
Worm
atp metabolic processGO:00460341760.125
generation of precursor metabolites and energyGO:0006091680.120
ribonucleoside monophosphate metabolic processGO:00091611870.114
ribonucleoside triphosphate metabolic processGO:00091994120.114
small molecule biosynthetic processGO:00442831570.108
cell cell signalingGO:00072671550.105
glycerol metabolic processGO:000607140.091
positive regulation of hydrolase activityGO:00513453310.084
cellular amino acid biosynthetic processGO:0008652300.081
positive regulation of programmed cell deathGO:00430682490.078
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.078
endocytosisGO:00068971590.076
Worm
glutamate biosynthetic processGO:000653730.076
positive regulation of proteolysisGO:00458621420.075
glutamate metabolic processGO:0006536100.075
lipid metabolic processGO:00066293810.072
regulation of proteolysisGO:00301622930.072
receptor mediated endocytosisGO:0006898840.070
Worm
sulfur compound biosynthetic processGO:0044272380.069
activation of cysteine type endopeptidase activityGO:0097202570.069
positive regulation of endopeptidase activityGO:0010950840.067
alpha amino acid biosynthetic processGO:1901607230.066
organonitrogen compound biosynthetic processGO:19015662000.063
purine ribonucleoside monophosphate metabolic processGO:00091671860.061
purine nucleoside monophosphate metabolic processGO:00091261860.059
defense responseGO:00069523150.056
purine nucleoside triphosphate metabolic processGO:00091444120.055
mitochondrial transportGO:0006839600.053
reproductionGO:0000003630.052
Worm
spermatid differentiationGO:004851540.051
transmembrane transportGO:00550853990.050
glutamine family amino acid metabolic processGO:0009064170.047
regulation of membrane potentialGO:0042391950.046
purine ribonucleoside triphosphate metabolic processGO:00092054110.045
regulation of cysteine type endopeptidase activityGO:20001161270.045
mitochondrion organizationGO:00070051560.045
nucleoside triphosphate metabolic processGO:00091414220.044
fatty acid metabolic processGO:00066311150.042
positive regulation of cell deathGO:00109422630.041
anion transportGO:00068201610.041
thioester metabolic processGO:0035383230.040
nadh dehydrogenase complex assemblyGO:0010257160.038
alpha amino acid metabolic processGO:1901605720.036
system processGO:00030083490.036
cellular ketone metabolic processGO:0042180800.035
aspartate family amino acid catabolic processGO:000906850.034
purine ribonucleoside monophosphate biosynthetic processGO:0009168160.034
innate immune responseGO:00450871780.034
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.034
small molecule catabolic processGO:0044282920.034
spermatid developmentGO:000728640.034
purine ribonucleoside metabolic processGO:00461284370.033
tricarboxylic acid metabolic processGO:007235040.032
mitochondrial membrane organizationGO:0007006400.032
agingGO:0007568660.029
central nervous system developmentGO:00074171230.028
alditol metabolic processGO:001940050.028
organic hydroxy compound metabolic processGO:19016151470.027
ribonucleotide biosynthetic processGO:0009260810.027
nervous system developmentGO:00073992930.026
protein acetylationGO:00064731160.026
secretion by cellGO:00329402260.026
nucleoside monophosphate metabolic processGO:00091231910.025
mitochondrial atp synthesis coupled electron transportGO:004277540.025
ribonucleotide catabolic processGO:00092614050.025
anatomical structure formation involved in morphogenesisGO:00486462840.024
cellular lipid metabolic processGO:00442553030.024
response to woundingGO:00096111680.024
rna interferenceGO:001624640.024
embryo development ending in birth or egg hatchingGO:0009792340.023
Worm
maintenance of locationGO:00512351120.022
adult locomotory behaviorGO:000834410.021
coenzyme biosynthetic processGO:0009108240.021
carbohydrate metabolic processGO:00059752070.021
cation transportGO:00068123310.020
organic acid biosynthetic processGO:0016053970.020
carboxylic acid catabolic processGO:0046395710.019
actin filament based processGO:00300292240.019
organic acid catabolic processGO:0016054710.019
dicarboxylic acid catabolic processGO:004364990.018
atp synthesis coupled electron transportGO:004277340.018
multicellular organismal response to stressGO:003355510.018
protein acylationGO:00435431380.018
ion transmembrane transportGO:00342203380.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
organophosphate biosynthetic processGO:00904071630.017
membrane organizationGO:00610242920.017
neuromuscular junction developmentGO:000752830.017
oogenesisGO:004847720.017
cellular macromolecular complex assemblyGO:00346223240.016
mitochondrial electron transport nadh to ubiquinoneGO:000612020.016
response to biotic stimulusGO:00096072760.016
single organism membrane organizationGO:00448022680.016
angiogenesisGO:00015251470.016
aerobic respirationGO:000906070.016
acyl coa biosynthetic processGO:007161660.015
muscle system processGO:0003012810.015
dna catabolic processGO:0006308490.015
lipid catabolic processGO:0016042840.015
pyruvate metabolic processGO:0006090260.015
chemical homeostasisGO:00488783060.015
negative regulation of transportGO:00510511760.015
growthGO:00400072020.015
posttranscriptional regulation of gene expressionGO:00106082130.015
locomotory behaviorGO:000762610.014
ion homeostasisGO:00508012300.014
response to hormoneGO:00097251750.014
brain developmentGO:0007420970.014
wound healingGO:00420601150.014
cell developmentGO:00484683280.014
reactive oxygen species metabolic processGO:0072593750.014
muscle structure developmentGO:0061061980.013
developmental process involved in reproductionGO:0003006660.013
regenerationGO:003109940.013
nucleoside biosynthetic processGO:0009163260.013
synaptic transmissionGO:0007268610.013
inorganic ion transmembrane transportGO:00986602310.013
protein localization to organelleGO:00333652800.013
acetyl coa biosynthetic process from pyruvateGO:000608640.013
immune responseGO:00069553070.013
purine ribonucleoside catabolic processGO:00461303980.013
cellular chemical homeostasisGO:00550821800.013
female gamete generationGO:000729220.012
regulation of apoptotic signaling pathwayGO:20012331750.012
internal protein amino acid acetylationGO:00064751010.012
purine ribonucleotide biosynthetic processGO:0009152790.012
nucleotide catabolic processGO:00091664080.012
acyl coa metabolic processGO:0006637230.012
nucleoside catabolic processGO:00091644080.012
negative regulation of intracellular signal transductionGO:19025321830.011
glycosyl compound biosynthetic processGO:1901659270.011
head developmentGO:00603221080.011
response to oxidative stressGO:00069791210.011
fear responseGO:004259600.011
organophosphate catabolic processGO:00464344300.011
cellular metal ion homeostasisGO:00068751460.011
behavioral defense responseGO:000220900.010
behavioral fear responseGO:000166200.010
nucleoside triphosphate catabolic processGO:00091433940.010
defense response to other organismGO:00985421290.010
response to drugGO:0042493810.010
positive regulation of cellular amino acid metabolic processGO:004576430.010

FH disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.867
inherited metabolic disorderDOID:6552420.867
amino acid metabolic disorderDOID:9252500.641
nervous system diseaseDOID:8634310.023
neuromuscular diseaseDOID:440380.023
neuropathyDOID:870520.023
immune system diseaseDOID:29141550.016
carbohydrate metabolic disorderDOID:2978550.016
organ system cancerDOID:00506861640.010
disease of cellular proliferationDOID:145661740.010
cancerDOID:1621670.010