Homo sapiens

162 known processes

ATRX

alpha thalassemia/mental retardation syndrome X-linked

(Aliases: XNP,SHS,MRXHF1,SFM1,ZNF-HX,RAD54L,JMS,XH2,ATR2,RAD54,MGC2094)

ATRX biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna conformation changeGO:00711031130.982
cellular response to dna damage stimulusGO:00069743790.907
Mouse
chromosome segregationGO:00070591140.882
organelle fissionGO:00482851490.878
chromatin modificationGO:00165682980.836
dna geometric changeGO:0032392320.812
mitotic cell cycleGO:00002783260.806
covalent chromatin modificationGO:00165692540.781
negative regulation of cell cycleGO:00457861930.760
negative regulation of mitotic cell cycleGO:00459301020.750
nucleosome assemblyGO:0006334500.727
chromatin organizationGO:00063253510.718
multicellular organismal agingGO:001025930.613
cell projection organizationGO:00300302520.612
Fly
chromatin assembly or disassemblyGO:0006333780.578
mitotic cell cycle processGO:19030472860.550
chordate embryonic developmentGO:0043009340.539
system processGO:00030083490.522
nuclear divisionGO:00002801280.514
dna replicationGO:00062601160.512
Mouse
post embryonic developmentGO:000979120.475
Worm
methylationGO:00322591060.458
anatomical structure formation involved in morphogenesisGO:00486462840.444
chromatin assemblyGO:0031497610.422
determination of adult lifespanGO:000834020.417
response to radiationGO:00093141510.404
cell projection morphogenesisGO:00488581290.401
Fly
cilium organizationGO:0044782680.397
regulation of cell cycleGO:00517263930.394
Mouse
response to abiotic stimulusGO:00096283360.369
sister chromatid cohesionGO:0007062240.368
regulation of action potentialGO:009890020.361
meiotic chromosome segregationGO:004513240.359
cilium assemblyGO:0042384630.319
cilium morphogenesisGO:0060271750.318
mitochondrion organizationGO:00070051560.284
single organism cellular localizationGO:19025803320.284
growthGO:00400072020.284
nucleosome organizationGO:0034728660.283
nuclear exportGO:0051168690.275
negative regulation of cell cycle phase transitionGO:1901988890.268
positive regulation of cellular component organizationGO:00511303760.266
Mouse
cell morphogenesisGO:00009022960.263
Fly
negative regulation of proteolysisGO:00458611320.247
mitotic nuclear divisionGO:00070671190.242
segmentationGO:003528240.239
sister chromatid segregationGO:0000819540.236
embryo developmentGO:00097901230.231
Worm
nucleoside triphosphate metabolic processGO:00091414220.224
g2 dna damage checkpointGO:0031572260.221
negative regulation of protein processingGO:00109551420.221
single organism reproductive processGO:0044702980.217
Mouse Worm
regulation of proteolysisGO:00301622930.217
histone methylationGO:0016571600.213
regulation of protein processingGO:00706131500.212
mitotic dna damage checkpointGO:0044773280.210
regulation of establishment of protein localizationGO:00702012420.205
double strand break repairGO:00063021010.203
cellular component morphogenesisGO:00329893140.197
Fly
neurological system processGO:00508771630.197
regulation of cell differentiationGO:00455953930.195
chemotaxisGO:00069351570.193
Fly
neuron differentiationGO:00301821380.192
Fly
generation of neuronsGO:00486991520.180
Fly
negative regulation of protein metabolic processGO:00512483910.179
cell part morphogenesisGO:00329901370.170
Fly
negative regulation of catabolic processGO:00098951040.168
mitotic sister chromatid segregationGO:0000070530.166
negative regulation of cellular protein metabolic processGO:00322693530.165
purine nucleoside catabolic processGO:00061523980.164
cellular response to endogenous stimulusGO:00714953360.162
dna duplex unwindingGO:0032508300.158
ribonucleoside catabolic processGO:00424544060.157
regulation of growthGO:00400081650.152
regulation of mitotic cell cycleGO:00073461890.151
regionalizationGO:0003002290.150
negative regulation of cell cycle processGO:00109481210.149
protein dna complex subunit organizationGO:0071824800.148
regulation of cell cycle phase transitionGO:19019871260.145
locomotory behaviorGO:000762610.144
memoryGO:000761330.141
agingGO:0007568660.134
regulation of protein maturationGO:19033171500.134
meiosis iGO:000712740.133
oogenesisGO:004847720.129
vesicle mediated transportGO:00161923710.125
cellular component assembly involved in morphogenesisGO:0010927730.125
sodium ion transportGO:0006814610.123
organelle assemblyGO:00709251760.119
dna packagingGO:0006323770.118
macromolecule methylationGO:0043414970.115
pattern specification processGO:0007389430.115
dna recombinationGO:0006310770.115
protein maturationGO:00516042330.111
regulation of protein catabolic processGO:00421761550.110
protein processingGO:00164852260.110
organelle localizationGO:0051640840.109
anatomical structure homeostasisGO:00602491000.107
Mouse
cardiovascular system developmentGO:00723582620.107
mitotic sister chromatid separationGO:0051306180.106
positive regulation of meiotic cell cycleGO:005144620.105
protein autophosphorylationGO:00467771230.103
positive regulation of protein phosphorylationGO:00019343130.101
neurogenesisGO:00220081690.101
Fly
regulation of chromosome segregationGO:0051983440.101
negative regulation of membrane protein ectodomain proteolysisGO:005104540.097
associative learningGO:000830610.097
cellular macromolecule catabolic processGO:00442653800.096
regulation of ion transmembrane transporter activityGO:0032412720.094
protein catabolic processGO:00301633250.094
histone modificationGO:00165702510.093
developmental process involved in reproductionGO:0003006660.093
Mouse Worm
cell developmentGO:00484683280.092
Mouse Fly
positive regulation of growthGO:0045927580.091
circulatory system developmentGO:00723592620.091
purine ribonucleoside monophosphate catabolic processGO:00091691580.090
regulation of cell morphogenesisGO:00226041530.086
atp metabolic processGO:00460341760.083
lipid localizationGO:00108761060.080
dna replication independent nucleosome organizationGO:0034724270.080
wnt signaling pathwayGO:00160551560.079
negative regulation of cellular catabolic processGO:0031330830.078
female gamete generationGO:000729220.078
sodium ion transmembrane transportGO:0035725590.077
telomere cappingGO:001623350.076
purine nucleotide catabolic processGO:00061954050.076
nucleoside triphosphate catabolic processGO:00091433940.075
regulation of mitotic metaphase anaphase transitionGO:0030071260.075
telomere organizationGO:0032200330.074
Mouse
positive regulation of transferase activityGO:00513472270.073
cell adhesionGO:00071553250.072
membrane protein proteolysisGO:0033619380.072
purine nucleoside monophosphate metabolic processGO:00091261860.072
enzyme linked receptor protein signaling pathwayGO:00071673030.072
nucleic acid phosphodiester bond hydrolysisGO:00903051020.071
positive regulation of cellular component biogenesisGO:00440891580.070
central nervous system developmentGO:00074171230.069
Mouse
nervous system developmentGO:00073992930.069
Mouse Fly
metal ion transportGO:00300012720.067
meiotic nuclear divisionGO:0007126100.067
protein alkylationGO:0008213740.065
biological adhesionGO:00226103310.065
protein dephosphorylationGO:0006470810.065
negative regulation of mitotic cell cycle phase transitionGO:1901991850.064
meiotic cell cycleGO:0051321130.063
reproductive processGO:00224141060.063
Mouse Worm
cell projection assemblyGO:00300311260.060
positive regulation of wnt signaling pathwayGO:0030177540.059
ion homeostasisGO:00508012300.059
maintenance of locationGO:00512351120.059
histone lysine methylationGO:0034968500.057
mitotic cell cycle phase transitionGO:00447721620.056
histone h3 k4 methylationGO:0051568270.056
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.056
regulation of cell developmentGO:00602841610.056
positive regulation of phosphorylationGO:00423273940.056
regulation of cellular component biogenesisGO:00440872810.055
cellular response to nitrogen compoundGO:19016991440.054
Mouse
regulation of nervous system developmentGO:0051960880.054
peptidyl serine phosphorylationGO:00181051010.054
protein methylationGO:0006479740.054
head developmentGO:00603221080.054
Mouse
positive regulation of kinase activityGO:00336742040.054
embryo development ending in birth or egg hatchingGO:0009792340.053
Worm
response to nitrogen compoundGO:19016981840.052
Mouse
rna splicingGO:00083801310.051
cell divisionGO:00513011680.051
dna repairGO:00062811980.051
regulation of chromosome organizationGO:00330441030.051
Mouse
regulation of protein transportGO:00512232130.049
protein localization to organelleGO:00333652800.049
regulation of transmembrane transporter activityGO:0022898740.049
cation transportGO:00068123310.048
cell cell signalingGO:00072671550.048
positive regulation of chromosome organizationGO:2001252410.048
Mouse
cell cycle checkpointGO:00000751170.048
signal transduction by phosphorylationGO:00230142970.047
Fly
regulation of mitotic cell cycle phase transitionGO:19019901180.047
cellular response to organonitrogen compoundGO:00714171240.046
taxisGO:00423301570.046
Fly
negative regulation of cell proliferationGO:00082852280.046
metaphase anaphase transition of cell cycleGO:0044784210.046
regulation of protein localizationGO:00328802960.046
dna integrity checkpointGO:0031570710.046
short term memoryGO:000761410.045
regulation of transporter activityGO:0032409820.045
response to biotic stimulusGO:00096072760.045
somitogenesisGO:000175620.045
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.044
reproductive structure developmentGO:0048608550.044
Mouse Worm
vasculature developmentGO:00019441810.044
cell growthGO:00160491600.044
purine ribonucleoside monophosphate metabolic processGO:00091671860.044
cognitionGO:0050890430.044
regulation of ion transmembrane transportGO:00347651320.043
transmembrane transportGO:00550853990.043
cellular response to abiotic stimulusGO:00712141170.043
protein dna complex assemblyGO:0065004640.042
neuron projection morphogenesisGO:0048812500.042
Fly
regulation of cellular protein catabolic processGO:1903362960.042
cation transmembrane transportGO:00986552380.041
sensory perceptionGO:00076001030.041
response to oxygen containing compoundGO:19017003690.041
regulation of developmental growthGO:0048638300.041
organophosphate catabolic processGO:00464344300.040
negative regulation of cellular component organizationGO:00511292350.040
regulation of chromatin modificationGO:1903308510.039
cellular response to oxygen containing compoundGO:19017012760.039
microtubule based processGO:00070172100.039
cellular homeostasisGO:00197251960.038
spermatid differentiationGO:004851540.038
regulation of kinase activityGO:00435493140.038
nucleocytoplasmic transportGO:00069131760.038
regulation of meiotic cell cycleGO:005144540.038
dephosphorylationGO:00163112090.038
positive regulation of protein complex assemblyGO:0031334860.037
negative regulation of organelle organizationGO:00106391260.037
chemical homeostasisGO:00488783060.036
forelimb morphogenesisGO:003513640.036
dna damage checkpointGO:0000077680.036
regulation of intracellular protein transportGO:00331571230.036
long term memoryGO:000761620.036
reproductive system developmentGO:0061458560.036
Mouse Worm
regulation of metaphase anaphase transition of cell cycleGO:1902099260.035
purine ribonucleoside catabolic processGO:00461303980.035
response to insulinGO:0032868450.035
regulation of ion homeostasisGO:2000021730.034
cell morphogenesis involved in differentiationGO:00009041440.034
Fly
regulation of transferase activityGO:00513383550.034
regulation of anatomical structure morphogenesisGO:00226032860.034
canonical wnt signaling pathwayGO:00600701160.034
regulation of protein autophosphorylationGO:0031952150.034
protein acetylationGO:00064731160.033
positive regulation of developmental processGO:00510943140.033
negative regulation of protein maturationGO:19033181420.033
membrane depolarization during action potentialGO:0086010100.033
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.032
neuron developmentGO:00486661130.032
Fly
rhythmic behaviorGO:000762220.031
mitotic spindle elongationGO:000002240.031
microtubule cytoskeleton organizationGO:00002261760.031
response to ionizing radiationGO:0010212650.031
positive regulation of protein autophosphorylationGO:003195490.031
negative regulation of dna replicationGO:0008156290.030
double strand break repair via homologous recombinationGO:0000724500.030
regulation of dna metabolic processGO:00510521530.030
Mouse
ribonucleoprotein complex assemblyGO:0022618780.030
reproductionGO:0000003630.029
Mouse Worm
reciprocal meiotic recombinationGO:000713140.029
signal transduction in response to dna damageGO:0042770570.029
Mouse
brain developmentGO:0007420970.028
Mouse
ribonucleoside monophosphate metabolic processGO:00091611870.028
monovalent inorganic cation transportGO:00156721280.028
cell cycle phase transitionGO:00447701730.028
humoral immune responseGO:0006959490.028
centrosome organizationGO:0051297580.028
regulation of cell growthGO:00015581350.027
blastoderm segmentationGO:000735020.027
nucleoside monophosphate catabolic processGO:00091251590.027
negative regulation of developmental processGO:00510932470.027
cell morphogenesis involved in neuron differentiationGO:0048667440.027
Fly
leukocyte differentiationGO:0002521980.027
neuromuscular junction developmentGO:000752830.027
mitotic sister chromatid cohesionGO:0007064120.027
metaphase anaphase transition of mitotic cell cycleGO:0007091210.027
regulation of cell adhesionGO:00301551660.026
skeletal system developmentGO:0001501790.026
mitotic g2 m transition checkpointGO:004481890.026
regulation of nucleocytoplasmic transportGO:0046822980.026
posttranscriptional regulation of gene expressionGO:00106082130.026
dna catabolic processGO:0006308490.026
cellular protein catabolic processGO:00442572610.026
inorganic ion transmembrane transportGO:00986602310.026
establishment of organelle localizationGO:0051656590.026
matingGO:000761810.026
establishment of protein localization to membraneGO:00901501210.025
cell activationGO:00017752130.025
atp catabolic processGO:00062001570.025
lymphocyte activationGO:00466491330.025
regulation of cellular response to stressGO:00801352440.025
Fly
neuron projection developmentGO:00311751060.025
Fly
inorganic cation transmembrane transportGO:00986621940.025
positive regulation of transportGO:00510503360.025
behaviorGO:00076101120.025
circadian sleep wake cycleGO:004274520.025
regulation of mitotic sister chromatid separationGO:0010965270.025
spindle assembly checkpointGO:0071173170.025
lipid storageGO:0019915280.025
regulation of ion transportGO:00432691890.024
cellular macromolecular complex assemblyGO:00346223240.024
negative regulation of cellular protein catabolic processGO:1903363380.024
regulation of dna replicationGO:0006275680.024
Mouse
cellular response to peptideGO:1901653590.024
cellular amine metabolic processGO:0044106410.024
spindle elongationGO:005123140.024
peptidyl serine modificationGO:00182091060.024
membrane organizationGO:00610242920.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
heart developmentGO:0007507950.023
immune effector processGO:00022521590.023
positive regulation of developmental growthGO:0048639160.023
circadian sleep wake cycle processGO:002241020.023
mitotic g2 dna damage checkpointGO:000709570.022
membrane protein ectodomain proteolysisGO:0006509330.022
meiotic cell cycle processGO:190304680.022
development of primary sexual characteristicsGO:0045137350.022
Mouse Worm
mrna splicing via spliceosomeGO:0000398890.022
regulation of chromatin organizationGO:1902275560.022
proteasomal protein catabolic processGO:00104981760.022
negative regulation of proteasomal protein catabolic processGO:1901799320.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
modification dependent macromolecule catabolic processGO:00436322120.021
multicellular organismal reproductive processGO:0048609400.021
Mouse
cell type specific apoptotic processGO:00972851250.021
peptidyl lysine methylationGO:0018022370.021
protein polyubiquitinationGO:00002091100.021
cellular response to oxidative stressGO:0034599850.021
positive regulation of protein localization to nucleusGO:1900182480.021
positive regulation of organelle organizationGO:00106381950.020
Mouse
response to alcoholGO:0097305640.020
negative regulation of apoptotic processGO:00430663160.020
jak stat cascadeGO:0007259460.020
cell fate determinationGO:000170930.020
regulation of transmembrane transportGO:00347621390.020
regulation of mitosisGO:0007088630.020
telomere maintenance via telomeraseGO:000700480.019
inner ear morphogenesisGO:004247240.019
positive regulation of chromatin modificationGO:1903310300.019
regulation of cellular amine metabolic processGO:0033238110.019
somatic recombination of immunoglobulin gene segmentsGO:001644740.019
regulation of intracellular transportGO:00323861950.019
reciprocal dna recombinationGO:003582540.019
negative regulation of phosphorylationGO:00423261740.019
organ morphogenesisGO:00098871470.019
reactive oxygen species biosynthetic processGO:190340940.019
leukocyte activationGO:00453211640.019
dna double strand break processingGO:0000729100.019
protein localization to membraneGO:00726571600.019
negative regulation of cell differentiationGO:00455961710.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
nuclear transportGO:00511691790.018
apoptotic signaling pathwayGO:00971902680.018
Fly
regulation of mrna metabolic processGO:1903311530.018
response to organonitrogen compoundGO:00102431560.018
ubiquitin dependent protein catabolic processGO:00065112060.018
mitotic dna integrity checkpointGO:0044774300.018
establishment of protein localization to organelleGO:00725941720.018
ribonucleotide catabolic processGO:00092614050.018
regulation of sodium ion transportGO:0002028240.018
chromatin remodelingGO:0006338550.018
positive regulation of cell growthGO:0030307480.018
cellular response to insulin stimulusGO:0032869410.017
negative regulation of cell morphogenesis involved in differentiationGO:0010771240.017
negative regulation of multicellular organismal processGO:00512413170.017
oocyte differentiationGO:000999420.017
circadian behaviorGO:004851220.017
purine ribonucleoside metabolic processGO:00461284370.017
negative regulation of translationGO:0017148370.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
Mouse
positive regulation of reactive oxygen species biosynthetic processGO:190342820.017
regulation of sodium ion transmembrane transporter activityGO:2000649170.017
action potentialGO:0001508340.017
regulation of cell cycle processGO:00105642660.017
Mouse
telomere maintenance via recombinationGO:000072240.017
peptidyl lysine modificationGO:00182051440.016
regulation of gene expression epigeneticGO:0040029730.016
Fly
regulation of sister chromatid segregationGO:0033045270.016
sensory perception of mechanical stimulusGO:0050954370.016
sensory organ developmentGO:0007423520.016
sensory perception of soundGO:0007605370.016
positive regulation of cell cycleGO:00457871400.016
Mouse
purine containing compound catabolic processGO:00725234110.016
peptidyl tyrosine dephosphorylationGO:0035335360.016
response to hormoneGO:00097251750.016
reactive oxygen species metabolic processGO:0072593750.016
translationGO:00064121320.015
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.015
neuron deathGO:0070997650.015
ossificationGO:00015031210.015
in utero embryonic developmentGO:000170180.015
intracellular protein transportGO:00068862700.015
response to decreased oxygen levelsGO:0036293960.014
negative regulation of chromosome organizationGO:2001251480.014
negative regulation of dna metabolic processGO:0051053570.014
cellular ketone metabolic processGO:0042180800.014
regulation of hormone levelsGO:00108171250.014
regulation of histone modificationGO:0031056470.014
male meiosisGO:000714010.014
nitrogen compound transportGO:00717051910.014
regulation of metal ion transportGO:00109591200.014
regulation of cellular ketone metabolic processGO:0010565500.014
regulation of cytoplasmic transportGO:19036491490.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
ion transmembrane transportGO:00342203380.014
interspecies interaction between organismsGO:00444191560.014
gonad developmentGO:0008406340.014
Mouse Worm
regulation of neuron apoptotic processGO:0043523350.014
purine nucleoside monophosphate catabolic processGO:00091281580.013
purine nucleoside triphosphate metabolic processGO:00091444120.013
protein homooligomerizationGO:00512601000.013
mrna processingGO:00063971330.013
positive regulation of histone modificationGO:0031058290.013
kidney developmentGO:0001822530.013
leukocyte mediated immunityGO:0002443590.013
gene silencingGO:0016458490.013
Fly
mitochondrial transportGO:0006839600.013
axonogenesisGO:0007409310.013
Fly
negative regulation of cellular amino acid metabolic processGO:004576320.013
regulation of rna splicingGO:0043484620.013
regulation of mrna processingGO:0050684480.013
regulation of cellular amino acid metabolic processGO:000652160.013
response to peptide hormoneGO:0043434610.012
protein export from nucleusGO:0006611290.012
blastocyst developmentGO:000182430.012
histone deacetylationGO:0016575320.012
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.012
eye developmentGO:0001654420.012
regulation of peptide secretionGO:0002791420.012
epithelial cell migrationGO:00106311190.012
anterior posterior pattern specificationGO:000995290.012
mitotic spindle assembly checkpointGO:0007094140.012
spermatid developmentGO:000728640.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
embryonic organ developmentGO:0048568360.012
multicellular organism reproductionGO:0032504420.012
Mouse
membrane depolarizationGO:0051899260.012
cytoplasmic transportGO:00164823790.012
response to bacteriumGO:00096171440.011
small gtpase mediated signal transductionGO:0007264780.011
rna dependent dna replicationGO:0006278160.011
negative regulation of immune system processGO:00026831360.011
negative regulation of chromosome segregationGO:0051985180.011
response to oxidative stressGO:00069791210.011
amine metabolic processGO:0009308440.011
oxidation reduction processGO:00551143960.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
negative regulation of protein catabolic processGO:0042177590.011
sexual reproductionGO:0019953370.011
Mouse
developmental growthGO:0048589480.011
motor neuron axon guidanceGO:000804520.011
t cell activationGO:0042110990.011
cellular response to decreased oxygen levelsGO:0036294510.011
isotype switchingGO:004519030.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
secretionGO:00469032540.011
regulation of cell motilityGO:20001452990.011
regulation of neuron differentiationGO:0045664700.011
response to external biotic stimulusGO:00432072610.011
negative regulation of neurogenesisGO:0050768260.011
viral life cycleGO:00190581320.011
negative regulation of mitotic sister chromatid segregationGO:0033048170.011
recombinational repairGO:0000725500.010
ribonucleoprotein complex subunit organizationGO:0071826810.010
response to nutrient levelsGO:0031667810.010
oocyte developmentGO:004859910.010
protein deacylationGO:0035601390.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
intracellular steroid hormone receptor signaling pathwayGO:0030518610.010
negative regulation of phosphorus metabolic processGO:00105632670.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
mitotic cell cycle checkpointGO:0007093680.010

ATRX disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.049
cancerDOID:1621670.049
immune system diseaseDOID:29141550.014
thalassemiaDOID:1024140.000
alpha thalassemiaDOID:109930.000