Homo sapiens

33 known processes

KPNB1

karyopherin (importin) beta 1

(Aliases: IPOB,MGC2155,MGC2156,Impnb,NTF97,IMB1,MGC2157,IPO1)

KPNB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nls bearing protein import into nucleusGO:000660721.000
Fly
protein targeting to nucleusGO:00447441040.998
cytoplasmic transportGO:00164823790.998
single organism cellular localizationGO:19025803320.997
nucleocytoplasmic transportGO:00069131760.997
nucleus organizationGO:0006997280.996
Yeast
intracellular protein transportGO:00068862700.996
protein localization to nucleusGO:00345041360.992
nuclear transportGO:00511691790.990
protein import into nucleusGO:00066061040.989
rna transportGO:0050658390.987
establishment of protein localization to organelleGO:00725941720.984
protein targetingGO:00066051870.981
protein importGO:00170381300.981
positive regulation of nucleocytoplasmic transportGO:0046824540.979
Fly
single organism nuclear importGO:19025931040.975
nuclear importGO:00511701060.975
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.947
protein localization to organelleGO:00333652800.943
positive regulation of protein transportGO:00512221350.926
Fly
establishment of rna localizationGO:0051236390.919
regulation of protein localizationGO:00328802960.904
Fly
positive regulation of intracellular protein transportGO:0090316760.882
Fly
nuclear pore organizationGO:0006999100.881
Yeast
nuclear exportGO:0051168690.878
regulation of nucleocytoplasmic transportGO:0046822980.878
Fly
smad protein import into nucleusGO:0007184130.876
enzyme linked receptor protein signaling pathwayGO:00071673030.857
positive regulation of cytoplasmic transportGO:1903651820.848
Fly
regulation of cytoplasmic transportGO:19036491490.826
Fly
positive regulation of protein import into nucleusGO:0042307460.792
Fly
establishment of ribosome localizationGO:003375340.779
rna localizationGO:0006403410.764
regulation of protein transportGO:00512232130.754
Fly
regulation of protein import into nucleusGO:0042306780.753
Fly
mitotic cell cycleGO:00002783260.742
Worm Fly
nucleic acid transportGO:0050657390.733
regulation of intracellular protein transportGO:00331571230.729
Fly
nucleobase containing compound transportGO:0015931510.680
positive regulation of intracellular transportGO:00323881040.649
Fly
nuclear pore complex assemblyGO:005129270.619
Yeast
rna export from nucleusGO:0006405330.561
positive regulation of nfat protein import into nucleusGO:005153330.558
Fly
ribosomal protein import into nucleusGO:000661020.543
post embryonic developmentGO:000979120.541
regulation of intracellular transportGO:00323861950.513
Fly
cellular macromolecular complex assemblyGO:00346223240.510
Yeast Fly
regulation of establishment of protein localizationGO:00702012420.493
Fly
positive regulation of transportGO:00510503360.483
Fly
regulation of mitotic cell cycleGO:00073461890.479
ribonucleoprotein complex export from nucleusGO:007142640.464
female gamete generationGO:000729220.459
Fly
regulation of protein localization to nucleusGO:1900180850.445
Fly
regulation of protein targetingGO:1903533910.437
Fly
mitotic cell cycle processGO:19030472860.423
Worm Fly
chromatin modificationGO:00165682980.416
cellular response to growth factor stimulusGO:00713631970.403
posttranscriptional regulation of gene expressionGO:00106082130.344
protein export from nucleusGO:0006611290.341
meiosis iGO:000712740.298
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.290
positive regulation of cellular component organizationGO:00511303760.284
neurogenesisGO:00220081690.268
regulation of chromosome segregationGO:0051983440.264
oogenesisGO:004847720.249
Fly
signal transduction by phosphorylationGO:00230142970.223
regulation of peptidase activityGO:00525471800.217
mapk cascadeGO:00001652880.213
sister chromatid segregationGO:0000819540.211
regulation of cell cycleGO:00517263930.211
ribonucleoprotein complex subunit organizationGO:0071826810.211
response to growth factorGO:00708482050.207
organelle fissionGO:00482851490.188
Fly
secretionGO:00469032540.187
nitrogen compound transportGO:00717051910.180
negative regulation of programmed cell deathGO:00430693210.180
ribosomal large subunit export from nucleusGO:000005530.178
centrosome organizationGO:0051297580.176
modification dependent protein catabolic processGO:00199412090.172
ribonucleoprotein complex localizationGO:007116640.172
cellular response to endogenous stimulusGO:00714953360.169
cellular response to cytokine stimulusGO:00713451810.169
microtubule cytoskeleton organizationGO:00002261760.159
Worm
ribosome localizationGO:003375040.152
positive regulation of transcription factor import into nucleusGO:0042993250.145
Fly
transcription factor import into nucleusGO:0042991400.145
Fly
regulation of nucleoside metabolic processGO:00091182090.145
Yeast
nervous system developmentGO:00073992930.141
modification dependent macromolecule catabolic processGO:00436322120.140
rna interferenceGO:001624640.138
cell divisionGO:00513011680.135
chromatin organizationGO:00063253510.133
single organism reproductive processGO:0044702980.127
Fly
regulation of gene expression epigeneticGO:0040029730.125
positive regulation of protein localization to nucleusGO:1900182480.118
Fly
small gtpase mediated signal transductionGO:0007264780.115
multicellular organismal agingGO:001025930.113
negative regulation of cell deathGO:00605483450.111
embryo developmentGO:00097901230.110
Worm
ribosomal subunit export from nucleusGO:000005440.107
nucleosome assemblyGO:0006334500.106
mitotic nuclear divisionGO:00070671190.104
Fly
posttranscriptional gene silencingGO:0016441250.104
taxisGO:00423301570.102
establishment of organelle localizationGO:0051656590.099
reproductive structure developmentGO:0048608550.096
vesicle mediated transportGO:00161923710.095
ras protein signal transductionGO:0007265730.095
regulation of small gtpase mediated signal transductionGO:00510561560.093
Yeast
dna conformation changeGO:00711031130.089
mrna transportGO:0051028300.089
peptidyl serine phosphorylationGO:00181051010.089
purine nucleoside triphosphate metabolic processGO:00091444120.087
chromatin remodelingGO:0006338550.084
regulation of response to external stimulusGO:00321012220.082
embryonic morphogenesisGO:0048598850.080
embryo development ending in birth or egg hatchingGO:0009792340.077
Worm
reproductive system developmentGO:0061458560.072
regulation of nucleotide catabolic processGO:00308112050.072
Yeast
gene silencing by rnaGO:0031047260.071
negative regulation of transportGO:00510511760.070
gtp catabolic processGO:00061842370.068
pore complex assemblyGO:004693190.067
Yeast
response to abiotic stimulusGO:00096283360.067
chromatin assembly or disassemblyGO:0006333780.065
nucleotide catabolic processGO:00091664080.065
regulation of cell divisionGO:00513021160.062
posttranscriptional gene silencing by rnaGO:0035194250.062
mitotic spindle organizationGO:0007052270.061
Worm
rna processingGO:00063962550.060
negative regulation of apoptotic processGO:00430663160.060
positive regulation of gtp catabolic processGO:00331261660.060
Yeast
nucleosome organizationGO:0034728660.059
mrna export from nucleusGO:0006406290.059
defense responseGO:00069523150.058
spindle organizationGO:0007051530.058
Worm
endocytosisGO:00068971590.058
positive regulation of catabolic processGO:00098963100.057
Yeast
regenerationGO:003109940.056
regulation of mitosisGO:0007088630.056
determination of adult lifespanGO:000834020.056
regulation of transferase activityGO:00513383550.055
ribonucleoprotein complex biogenesisGO:00226131160.055
phagocytosisGO:0006909420.054
oocyte developmentGO:004859910.054
spermatid differentiationGO:004851540.054
positive regulation of nucleotide metabolic processGO:00459812300.054
Yeast
protein catabolic processGO:00301633250.053
cellular amine metabolic processGO:0044106410.053
Yeast
purine ribonucleoside catabolic processGO:00461303980.052
regulation of nucleotide metabolic processGO:00061402690.051
Yeast
cell cycle phase transitionGO:00447701730.051
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.048
organic hydroxy compound metabolic processGO:19016151470.048
Yeast
multicellular organismal reproductive processGO:0048609400.048
Fly
regulation of sister chromatid segregationGO:0033045270.047
nuclear divisionGO:00002801280.047
Fly
regulation of locomotionGO:00400123290.046
regulation of ras protein signal transductionGO:00465781550.046
Yeast
negative regulation of cytoplasmic transportGO:1903650460.046
positive regulation of hydrolase activityGO:00513453310.045
Yeast
negative regulation of growthGO:0045926970.044
muscle structure developmentGO:0061061980.044
macromolecule methylationGO:0043414970.041
ribonucleoside triphosphate catabolic processGO:00092033910.041
positive regulation of cellular catabolic processGO:00313312840.041
Yeast
centrosome cycleGO:0007098320.040
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.040
covalent chromatin modificationGO:00165692540.039
sensory organ developmentGO:0007423520.039
response to external biotic stimulusGO:00432072610.039
negative regulation of cell cycleGO:00457861930.039
chromatin assemblyGO:0031497610.039
segmentationGO:003528240.038
gtp metabolic processGO:00460392390.038
ribonucleoprotein complex assemblyGO:0022618780.038
regulation of purine nucleotide catabolic processGO:00331212050.038
Yeast
cell junction assemblyGO:0034329670.037
reproductive processGO:00224141060.037
Fly
negative regulation of developmental processGO:00510932470.037
anterior posterior axis specification embryoGO:000859520.036
regulation of endopeptidase activityGO:00525481700.036
oocyte differentiationGO:000999420.036
gene silencingGO:0016458490.036
reproductionGO:0000003630.036
Worm Fly
mrna metabolic processGO:00160711750.035
regulation of cellular amino acid metabolic processGO:000652160.035
locomotory behaviorGO:000762610.034
response to oxidative stressGO:00069791210.034
organelle assemblyGO:00709251760.034
cellular response to oxygen containing compoundGO:19017012760.033
embryonic epithelial tube formationGO:000183840.032
cation transportGO:00068123310.032
establishment or maintenance of cytoskeleton polarityGO:003095230.032
response to oxygen containing compoundGO:19017003690.032
amine metabolic processGO:0009308440.032
Yeast
positive regulation of proteolysisGO:00458621420.031
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.031
response to transforming growth factor betaGO:0071559940.031
regulation of cell cycle phase transitionGO:19019871260.030
muscle organ developmentGO:0007517560.030
regulation of dna metabolic processGO:00510521530.030
positive regulation of nucleotide catabolic processGO:00308131850.029
Yeast
regulation of cellular response to growth factor stimulusGO:0090287760.029
negative regulation of protein metabolic processGO:00512483910.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
negative regulation of cellular protein metabolic processGO:00322693530.028
cell type specific apoptotic processGO:00972851250.028
organelle localizationGO:0051640840.027
protein polyubiquitinationGO:00002091100.027
blastoderm segmentationGO:000735020.025
positive regulation of gtpase activityGO:00435471660.025
Yeast
microtubule based processGO:00070172100.025
Worm
tripartite regional subdivisionGO:000735120.025
regulation of cellular ketone metabolic processGO:0010565500.025
cellular amino acid metabolic processGO:00065201160.025
spermatid developmentGO:000728640.025
neural tube formationGO:000184130.025
positive regulation of apoptotic processGO:00430652460.025
histone methylationGO:0016571600.025
negative regulation of catabolic processGO:00098951040.025
negative regulation of nucleocytoplasmic transportGO:0046823370.025
response to uvGO:0009411730.024
regulation of protein catabolic processGO:00421761550.024
rna 3 end processingGO:0031123350.024
positive regulation of cell divisionGO:0051781590.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
Fly
cell cell signalingGO:00072671550.023
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.023
chordate embryonic developmentGO:0043009340.023
chemotaxisGO:00069351570.022
cell morphogenesis involved in differentiationGO:00009041440.022
response to oxygen levelsGO:00704821000.022
nucleoside triphosphate catabolic processGO:00091433940.022
nucleoside phosphate catabolic processGO:19012924120.022
glycosyl compound catabolic processGO:19016584130.022
immune effector processGO:00022521590.022
positive regulation of cell cycleGO:00457871400.021
intrinsic apoptotic signaling pathwayGO:00971931270.021
regulation of membrane potentialGO:0042391950.021
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.021
nucleoside triphosphate metabolic processGO:00091414220.021
protein methylationGO:0006479740.021
vasculature developmentGO:00019441810.020
regulation of protein stabilityGO:0031647870.020
maturation of 5 8s rrnaGO:000046080.020
microtubule organizing center organizationGO:0031023620.020
cellular response to decreased oxygen levelsGO:0036294510.020
tube developmentGO:00352951250.019
endomembrane system organizationGO:00102561960.019
regulation of chromosome organizationGO:00330441030.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
negative regulation of cell cycle processGO:00109481210.019
positive regulation of mitotic cell cycleGO:0045931600.019
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.019
ubiquitin dependent protein catabolic processGO:00065112060.019
protein foldingGO:0006457380.019
anterior posterior axis specificationGO:000994820.019
regulation of bindingGO:00510981110.019
centrosome duplicationGO:0051298280.018
nfat protein import into nucleusGO:005153150.018
Fly
neuron projection morphogenesisGO:0048812500.018
regulation of cell cycle processGO:00105642660.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
negative regulation of cellular component organizationGO:00511292350.018
developmental growthGO:0048589480.018
developmental process involved in reproductionGO:0003006660.018
Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.018
Yeast
cellular response to oxidative stressGO:0034599850.018
regulation of cellular amine metabolic processGO:0033238110.018
response to lipidGO:00339932060.018
positive regulation of bindingGO:0051099450.017
blastocyst developmentGO:000182430.017
positive regulation of nucleoside metabolic processGO:00459791860.017
Yeast
cell morphogenesis involved in neuron differentiationGO:0048667440.017
protein autophosphorylationGO:00467771230.017
angiogenesisGO:00015251470.017
neuromuscular junction developmentGO:000752830.017
regulation of kinase activityGO:00435493140.017
morphogenesis of embryonic epitheliumGO:001633140.017
regulation of cellular response to stressGO:00801352440.017
regulation of system processGO:00440571010.017
ribonucleotide catabolic processGO:00092614050.017
positive regulation of cell cycle processGO:00900681060.017
cellular protein catabolic processGO:00442572610.017
regulation of proteasomal protein catabolic processGO:0061136870.017
negative regulation of neuron deathGO:1901215320.017
response to nitrogen compoundGO:19016981840.017
purine ribonucleoside metabolic processGO:00461284370.017
cellular protein complex assemblyGO:00436231880.016
Yeast Fly
response to cytokineGO:00340972320.016
nucleoside catabolic processGO:00091644080.016
lipid biosynthetic processGO:00086101770.016
Yeast
histone exchangeGO:004348630.016
ribonucleoside catabolic processGO:00424544060.016
peptidyl serine modificationGO:00182091060.016
positive regulation of ras gtpase activityGO:00323201170.016
Yeast
protein acetylationGO:00064731160.016
tube morphogenesisGO:0035239950.016
neuron differentiationGO:00301821380.016
cell fate determinationGO:000170930.016
cell fate commitmentGO:0045165270.015
response to hypoxiaGO:0001666960.015
cellular ketone metabolic processGO:0042180800.015
multicellular organism reproductionGO:0032504420.015
Fly
positive regulation of endopeptidase activityGO:0010950840.015
positive regulation of cellular component biogenesisGO:00440891580.015
methylationGO:00322591060.015
eye developmentGO:0001654420.015
cellular response to organonitrogen compoundGO:00714171240.015
regulation of oocyte developmentGO:006028110.015
cell developmentGO:00484683280.015
Fly
positive regulation of cellular amine metabolic processGO:003324070.015
protein dna complex subunit organizationGO:0071824800.014
photoreceptor cell differentiationGO:004653020.014
adult locomotory behaviorGO:000834410.014
cell projection morphogenesisGO:00488581290.014
cellular macromolecule catabolic processGO:00442653800.014
regulation of gtp catabolic processGO:00331241800.013
Yeast
negative regulation of protein modification processGO:00314002000.013
negative regulation of phosphorylationGO:00423261740.013
ncrna metabolic processGO:00346601080.013
purine ribonucleotide catabolic processGO:00091544040.013
negative regulation of phosphate metabolic processGO:00459362670.013
muscle cell differentiationGO:0042692630.013
central nervous system developmentGO:00074171230.013
rna splicingGO:00083801310.013
regulation of body fluid levelsGO:0050878990.013
actin filament based processGO:00300292240.013
Fly
compound eye developmentGO:004874910.013
mrna processingGO:00063971330.012
microtubule polymerization or depolymerizationGO:0031109370.012
generation of neuronsGO:00486991520.012
striated muscle cell differentiationGO:0051146430.012
regulation of mapk cascadeGO:00434082620.012
spindle assembly involved in mitosisGO:0090307120.012
cellular response to dna damage stimulusGO:00069743790.012
negative regulation of proteasomal protein catabolic processGO:1901799320.012
positive regulation of developmental processGO:00510943140.012
regulation of protein kinase activityGO:00458592890.012
regulation of cell differentiationGO:00455953930.012
regulation of proteolysisGO:00301622930.012
single organismal cell cell adhesionGO:00163371480.012
ribosome biogenesisGO:0042254480.011
negative regulation of catalytic activityGO:00430863350.011
regulation of nuclear divisionGO:0051783650.011
regulation of gtpase activityGO:00430871800.011
Yeast
innate immune responseGO:00450871780.011
cation transmembrane transportGO:00986552380.011
regulation of mrna metabolic processGO:1903311530.011
negative regulation of transferase activityGO:00513481240.011
regulation of developmental growthGO:0048638300.011
regulation of chromatin organizationGO:1902275560.011
positive regulation of mrna metabolic processGO:1903313190.011
negative regulation of cell differentiationGO:00455961710.011
atp dependent chromatin remodelingGO:0043044250.011
protein stabilizationGO:0050821640.011
purine containing compound catabolic processGO:00725234110.011
regulation of cellular protein catabolic processGO:1903362960.011
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.011
regulation of cellular component movementGO:00512703340.011
cell projection organizationGO:00300302520.011
regulation of purine nucleotide metabolic processGO:19005422640.011
Yeast
protein maturationGO:00516042330.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.010
neuroblast proliferationGO:000740540.010
guanosine containing compound metabolic processGO:19010682440.010
regulation of mitotic metaphase anaphase transitionGO:0030071260.010
multi organism reproductive processGO:0044703540.010
Fly
response to lipopolysaccharideGO:0032496700.010
positive regulation of organelle organizationGO:00106381950.010
protein localization to cell surfaceGO:0034394280.010
lymphocyte activationGO:00466491330.010
rna splicing via transesterification reactionsGO:0000375900.010

KPNB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.012
organ system cancerDOID:00506861640.012
cancerDOID:1621670.012
central nervous system diseaseDOID:3311860.012
nervous system diseaseDOID:8634310.012