Homo sapiens

0 known processes

PLEKHG4B

pleckstrin homology domain containing, family G (with RhoGef domain) member 4B

(Aliases: FLJ43173,KIAA1909)

PLEKHG4B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.065
cellular amino acid metabolic processGO:00065201160.059
regulation of cellular amino acid metabolic processGO:000652160.057
amine metabolic processGO:0009308440.056
positive regulation of cellular amino acid metabolic processGO:004576430.055
cellular amine metabolic processGO:0044106410.055
regulation of cellular amine metabolic processGO:0033238110.053
regulation of cellular ketone metabolic processGO:0010565500.050
positive regulation of cellular amine metabolic processGO:003324070.040
regulation of cell differentiationGO:00455953930.039
multicellular organismal agingGO:001025930.039
cellular ketone metabolic processGO:0042180800.038
ras protein signal transductionGO:0007265730.037
small gtpase mediated signal transductionGO:0007264780.036
segmentationGO:003528240.036
determination of adult lifespanGO:000834020.034
actin filament based processGO:00300292240.034
cell developmentGO:00484683280.033
locomotory behaviorGO:000762610.033
positive regulation of phosphorylationGO:00423273940.032
morphogenesis of embryonic epitheliumGO:001633140.031
cell morphogenesisGO:00009022960.030
female gamete generationGO:000729220.030
enzyme linked receptor protein signaling pathwayGO:00071673030.030
positive regulation of cellular component organizationGO:00511303760.029
purine containing compound catabolic processGO:00725234110.029
regulation of anatomical structure morphogenesisGO:00226032860.029
positive regulation of hydrolase activityGO:00513453310.029
positive regulation of cell proliferationGO:00082843010.029
transmembrane transportGO:00550853990.028
positive regulation of transportGO:00510503360.028
cellular response to endogenous stimulusGO:00714953360.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
nervous system developmentGO:00073992930.028
cytoplasmic transportGO:00164823790.028
cellular component morphogenesisGO:00329893140.028
hindbrain developmentGO:003090230.028
regulation of cellular component movementGO:00512703340.027
organophosphate catabolic processGO:00464344300.027
purine ribonucleoside metabolic processGO:00461284370.027
glycosyl compound catabolic processGO:19016584130.027
ion transmembrane transportGO:00342203380.027
negative regulation of cellular protein metabolic processGO:00322693530.027
cation transportGO:00068123310.027
peripheral nervous system developmentGO:000742220.027
regulation of transferase activityGO:00513383550.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
ribonucleoside catabolic processGO:00424544060.027
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.027
purine ribonucleoside catabolic processGO:00461303980.026
negative regulation of protein metabolic processGO:00512483910.026
nucleoside phosphate catabolic processGO:19012924120.026
system processGO:00030083490.026
lipid metabolic processGO:00066293810.026
ribonucleotide catabolic processGO:00092614050.026
regulation of protein localizationGO:00328802960.026
oogenesisGO:004847720.026
immune responseGO:00069553070.026
purine nucleoside catabolic processGO:00061523980.026
inner ear morphogenesisGO:004247240.025
cellular macromolecular complex assemblyGO:00346223240.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
defense responseGO:00069523150.025
membrane organizationGO:00610242920.025
embryonic epithelial tube formationGO:000183840.025
nucleoside catabolic processGO:00091644080.025
organ formationGO:004864530.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
cellular macromolecule catabolic processGO:00442653800.025
negative regulation of catalytic activityGO:00430863350.025
purine nucleotide catabolic processGO:00061954050.025
response to abiotic stimulusGO:00096283360.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
nucleoside triphosphate catabolic processGO:00091433940.024
single organism cellular localizationGO:19025803320.024
nucleoside triphosphate metabolic processGO:00091414220.024
regulation of kinase activityGO:00435493140.024
wnt signaling pathwayGO:00160551560.024
cation transmembrane transportGO:00986552380.024
regulation of locomotionGO:00400123290.024
negative regulation of multicellular organismal processGO:00512413170.024
regulation of cell motilityGO:20001452990.024
protein maturationGO:00516042330.024
memoryGO:000761330.023
positive regulation of protein phosphorylationGO:00019343130.023
cell projection organizationGO:00300302520.023
negative regulation of cell deathGO:00605483450.023
negative regulation of phosphate metabolic processGO:00459362670.023
anatomical structure formation involved in morphogenesisGO:00486462840.023
positive regulation of catabolic processGO:00098963100.023
regulation of proteolysisGO:00301622930.023
cellular lipid metabolic processGO:00442553030.023
negative regulation of phosphorus metabolic processGO:00105632670.023
negative regulation of programmed cell deathGO:00430693210.023
regulation of establishment of protein localizationGO:00702012420.023
mitotic cell cycleGO:00002783260.023
rho protein signal transductionGO:0007266260.022
nucleotide catabolic processGO:00091664080.022
regulation of cell cycleGO:00517263930.022
forebrain generation of neuronsGO:002187230.022
single organism membrane organizationGO:00448022680.022
negative regulation of apoptotic processGO:00430663160.022
signal transduction by phosphorylationGO:00230142970.022
blastoderm segmentationGO:000735020.022
neuromuscular junction developmentGO:000752830.022
cellular response to dna damage stimulusGO:00069743790.022
positive regulation of cellular catabolic processGO:00313312840.022
response to oxygen containing compoundGO:19017003690.022
purine nucleoside triphosphate catabolic processGO:00091463920.021
apoptotic signaling pathwayGO:00971902680.021
biological adhesionGO:00226103310.021
organonitrogen compound biosynthetic processGO:19015662000.021
protein catabolic processGO:00301633250.021
regulation of cell migrationGO:00303342890.021
intracellular protein transportGO:00068862700.021
regulation of nucleotide metabolic processGO:00061402690.021
mitotic cell cycle processGO:19030472860.021
regulation of response to external stimulusGO:00321012220.020
mapk cascadeGO:00001652880.020
negative regulation of cellular amine metabolic processGO:003323930.020
chemical homeostasisGO:00488783060.020
anion transportGO:00068201610.020
regulation of protein kinase activityGO:00458592890.020
maintenance of locationGO:00512351120.020
response to cytokineGO:00340972320.020
regulation of cell developmentGO:00602841610.020
circulatory system developmentGO:00723592620.020
cytokine productionGO:00018162470.020
positive regulation of developmental processGO:00510943140.020
regulation of intracellular transportGO:00323861950.020
protein processingGO:00164852260.020
nitrogen compound transportGO:00717051910.019
cellular response to oxygen containing compoundGO:19017012760.019
cellular protein catabolic processGO:00442572610.019
vesicle mediated transportGO:00161923710.019
epithelium developmentGO:00604292270.019
metal ion transportGO:00300012720.019
organ morphogenesisGO:00098871470.019
anterior posterior axis specificationGO:000994820.019
protein localization to organelleGO:00333652800.019
cellular protein complex assemblyGO:00436231880.019
specification of organ identityGO:001009230.019
anterior posterior axis specification embryoGO:000859520.018
negative regulation of developmental processGO:00510932470.018
photoreceptor cell differentiationGO:004653020.018
spermatid differentiationGO:004851540.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
inorganic ion transmembrane transportGO:00986602310.018
regenerationGO:003109940.018
regulation of cellular component biogenesisGO:00440872810.018
tissue morphogenesisGO:0048729960.018
cation homeostasisGO:00550801890.018
regulation of cellular response to stressGO:00801352440.018
response to external biotic stimulusGO:00432072610.018
secretionGO:00469032540.018
microtubule based processGO:00070172100.018
lipid biosynthetic processGO:00086101770.018
secretion by cellGO:00329402260.018
metencephalon developmentGO:002203720.018
carbohydrate derivative biosynthetic processGO:19011372070.018
gtp metabolic processGO:00460392390.018
guanosine containing compound metabolic processGO:19010682440.017
cell cell signalingGO:00072671550.017
guanosine containing compound catabolic processGO:19010692390.017
regulation of neural precursor cell proliferationGO:200017740.017
oocyte differentiationGO:000999420.017
positive regulation of transferase activityGO:00513472270.017
regulation of wnt signaling pathwayGO:00301111230.017
adult locomotory behaviorGO:000834410.017
negative regulation of cellular component organizationGO:00511292350.017
chromatin organizationGO:00063253510.017
cardiac muscle cell contractionGO:008600340.017
response to biotic stimulusGO:00096072760.017
nerve developmentGO:002167540.017
positive regulation of cell differentiationGO:00455972110.017
positive regulation of protein kinase activityGO:00458601900.017
regulation of mapk cascadeGO:00434082620.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
matingGO:000761810.017
cardiovascular system developmentGO:00723582620.017
protein targetingGO:00066051870.017
regulation of cytokine productionGO:00018172320.017
purine ribonucleotide catabolic processGO:00091544040.017
dephosphorylationGO:00163112090.017
cell adhesionGO:00071553250.017
cell activationGO:00017752130.017
positive regulation of kinase activityGO:00336742040.017
regulation of secretion by cellGO:19035301770.017
endomembrane system organizationGO:00102561960.017
neurogenesisGO:00220081690.017
cell fate determinationGO:000170930.017
regulation of cell cycle processGO:00105642660.017
compound eye developmentGO:004874910.016
forebrain neuron differentiationGO:002187930.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
positive regulation of cell migrationGO:00303351720.016
neural tube formationGO:000184130.016
regulation of protein transportGO:00512232130.016
innate immune responseGO:00450871780.016
oocyte developmentGO:004859910.016
negative regulation of hydrolase activityGO:00513461820.016
regulation of purine nucleotide catabolic processGO:00331212050.016
cellular response to cytokine stimulusGO:00713451810.016
spermatid developmentGO:000728640.016
positive regulation of nucleotide metabolic processGO:00459812300.016
copulationGO:000762010.016
regulation of nucleotide catabolic processGO:00308112050.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of endopeptidase activityGO:00525481700.016
negative regulation of protein modification processGO:00314002000.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of programmed cell deathGO:00430682490.016
ubiquitin dependent protein catabolic processGO:00065112060.016
associative learningGO:000830610.016
regulation of secretionGO:00510461940.016
divalent inorganic cation homeostasisGO:00725071360.016
regulation of cell morphogenesisGO:00226041530.016
inorganic cation transmembrane transportGO:00986621940.016
neuron differentiationGO:00301821380.016
central nervous system developmentGO:00074171230.016
regulation of cytoskeleton organizationGO:00514931770.015
cellular homeostasisGO:00197251960.015
gtp catabolic processGO:00061842370.015
positive regulation of nucleoside metabolic processGO:00459791860.015
chromatin modificationGO:00165682980.015
epidermis morphogenesisGO:004873030.015
reactive oxygen species biosynthetic processGO:190340940.015
ion homeostasisGO:00508012300.015
organic anion transportGO:00157111030.015
positive regulation of immune system processGO:00026842830.015
cell part morphogenesisGO:00329901370.015
generation of neuronsGO:00486991520.015
organophosphate biosynthetic processGO:00904071630.015
divalent inorganic cation transportGO:00725111580.015
tripartite regional subdivisionGO:000735120.015
response to other organismGO:00517072610.015
divalent metal ion transportGO:00708381520.015
cellular metal ion homeostasisGO:00068751460.015
protein modification by small protein conjugationGO:00324463420.015
neurological system processGO:00508771630.015
single organism cell adhesionGO:00986021790.015
reactive oxygen species metabolic processGO:0072593750.015
negative regulation of cell differentiationGO:00455961710.015
canonical wnt signaling pathwayGO:00600701160.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
cell projection morphogenesisGO:00488581290.015
cerebellum developmentGO:002154920.015
carbohydrate metabolic processGO:00059752070.015
regulation of apoptotic signaling pathwayGO:20012331750.015
proteasomal protein catabolic processGO:00104981760.015
cellular cation homeostasisGO:00300031630.015
modification dependent macromolecule catabolic processGO:00436322120.015
metal ion homeostasisGO:00550651690.015
response to woundingGO:00096111680.015
cell growthGO:00160491600.015
rhythmic behaviorGO:000762220.015
positive regulation of cell motilityGO:20001471770.015
serotonin transportGO:000683730.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
modification dependent protein catabolic processGO:00199412090.015
actin cytoskeleton organizationGO:00300362070.015
glycerolipid metabolic processGO:00464861070.015
organelle assemblyGO:00709251760.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
regulation of protein serine threonine kinase activityGO:00719001790.014
response to organic cyclic compoundGO:00140702040.014
regulation of peptidase activityGO:00525471800.014
positive regulation of cellular component movementGO:00512721810.014
regulation of immune responseGO:00507762010.014
posttranscriptional regulation of gene expressionGO:00106082130.014
cellular ion homeostasisGO:00068731680.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
cellular chemical homeostasisGO:00550821800.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of cell adhesionGO:00301551660.014
chemotaxisGO:00069351570.014
positive regulation of nucleotide catabolic processGO:00308131850.014
positive regulation of secretion by cellGO:19035321080.014
protein localization to membraneGO:00726571600.014
positive regulation of cell deathGO:00109422630.014
peptidyl tyrosine phosphorylationGO:00181081700.014
neuroblast proliferationGO:000740540.014
regulation of protein maturationGO:19033171500.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
protein ubiquitinationGO:00165673140.014
cellular response to organonitrogen compoundGO:00714171240.014
regulation of cytoplasmic transportGO:19036491490.014
cell morphogenesis involved in differentiationGO:00009041440.014
response to growth factorGO:00708482050.014
negative regulation of cell proliferationGO:00082852280.014
microtubule cytoskeleton organizationGO:00002261760.014
response to nitrogen compoundGO:19016981840.014
motor neuron axon guidanceGO:000804520.014
head developmentGO:00603221080.014
regulation of growthGO:00400081650.014
sequestering of metal ionGO:0051238240.013
i kappab kinase nf kappab signalingGO:00072491660.013
limbic system developmentGO:002176130.013
positive regulation of organelle organizationGO:00106381950.013
regulation of protein processingGO:00706131500.013
regulation of nucleoside metabolic processGO:00091182090.013
neurotransmitter secretionGO:000726940.013
positive regulation of secretionGO:00510471160.013
establishment of protein localization to organelleGO:00725941720.013
positive regulation of cellular component biogenesisGO:00440891580.013
cell projection assemblyGO:00300311260.013
positive regulation of locomotionGO:00400171860.013
cell cycle phase transitionGO:00447701730.013
reactive nitrogen species metabolic processGO:200105730.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
morphogenesis of a polarized epitheliumGO:000173830.013
positive regulation of mapk cascadeGO:00434101900.013
protein oligomerizationGO:00512591730.013
glycine importGO:003623310.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of protein catabolic processGO:00421761550.013
cellular response to nitrogen compoundGO:19016991440.013
negative regulation of cell cycleGO:00457861930.013
regulation of multi organism processGO:00439001570.013
response to fungusGO:000962040.013
negative regulation of transportGO:00510511760.013
small molecule biosynthetic processGO:00442831570.013
single organism carbohydrate metabolic processGO:00447231930.013
endocytosisGO:00068971590.013
muscle contractionGO:0006936730.013
tube closureGO:006060630.013
regulation of actin filament based processGO:00329701410.013
actin filament based movementGO:0030048170.013
positive regulation of proteolysisGO:00458621420.013
taxisGO:00423301570.013
g protein coupled receptor signaling pathwayGO:00071862070.013
interspecies interaction between organismsGO:00444191560.013
rna processingGO:00063962550.013
somitogenesisGO:000175620.013
primary neural tube formationGO:001402030.013
peptidyl tyrosine modificationGO:00182121700.013
actin mediated cell contractionGO:0070252120.013
covalent chromatin modificationGO:00165692540.013
negative regulation of phosphorylationGO:00423261740.013
sulfur compound metabolic processGO:00067901010.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
regulation of gtpase activityGO:00430871800.013
histone modificationGO:00165702510.013
protein autophosphorylationGO:00467771230.013
tissue migrationGO:00901301190.013
epithelial cell differentiationGO:00308551410.012
immune effector processGO:00022521590.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
negative regulation of protein phosphorylationGO:00019331400.012
calcium ion homeostasisGO:00550741220.012
regulation of dna metabolic processGO:00510521530.012
nuclear transportGO:00511691790.012
response to lipidGO:00339932060.012
regulation of ion transportGO:00432691890.012
negative regulation of protein maturationGO:19033181420.012
tissue regenerationGO:004224630.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
dna repairGO:00062811980.012
growthGO:00400072020.012
mitotic cell cycle phase transitionGO:00447721620.012
anatomical structure homeostasisGO:00602491000.012
response to radiationGO:00093141510.012
syncytium formation by plasma membrane fusionGO:000076820.012
neuron developmentGO:00486661130.012
organic hydroxy compound transportGO:0015850630.012
positive regulation of intracellular transportGO:00323881040.012
regulation of mitotic cell cycleGO:00073461890.012
glycoprotein metabolic processGO:00091001100.012
leukocyte activationGO:00453211640.012
response to axon injuryGO:004867810.012
negative regulation of synaptic transmissionGO:005080520.012
cell divisionGO:00513011680.012
positive regulation of wnt signaling pathwayGO:0030177540.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
positive regulation of cell developmentGO:0010720920.012
nucleocytoplasmic transportGO:00069131760.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
sequestering of calcium ionGO:0051208170.012
positive regulation of gtpase activityGO:00435471660.012
thymus developmentGO:004853830.012
regulation of ras gtpase activityGO:00323181280.012
regulation of defense responseGO:00313471540.012
phospholipid metabolic processGO:0006644990.012
sex determinationGO:000753030.011
brain developmentGO:0007420970.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
positive regulation of gtp catabolic processGO:00331261660.011
positive regulation of protein transportGO:00512221350.011
regulation of gtp catabolic processGO:00331241800.011
striated muscle contractionGO:0006941520.011
mitochondrion organizationGO:00070051560.011
muscle system processGO:0003012810.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
spinal cord developmentGO:002151040.011
cell substrate adhesionGO:00315891320.011
neural tube closureGO:000184330.011
lung alveolus developmentGO:004828640.011
visual behaviorGO:000763220.011
ameboidal type cell migrationGO:00016671350.011
establishment of protein localization to membraneGO:00901501210.011
positive regulation of cell cycleGO:00457871400.011
regulation of vesicle mediated transportGO:00606271300.011
cellular response to lipidGO:00713961270.011
regulation of anatomical structure sizeGO:00900661010.011
endosomal transportGO:00161971290.011
regulation of protein complex assemblyGO:00432541470.011
regulation of cell projection organizationGO:00313441070.011
regulation of meiotic cell cycleGO:005144540.011
male genitalia developmentGO:003053910.011
nucleoside monophosphate metabolic processGO:00091231910.011
neuron projection developmentGO:00311751060.011
dna replicationGO:00062601160.011
epithelium migrationGO:00901321190.011
monovalent inorganic cation transportGO:00156721280.011
negative regulation of organelle organizationGO:00106391260.011
embryo developmentGO:00097901230.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
regulation of membrane potentialGO:0042391950.011
pituitary gland developmentGO:002198320.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
establishment of planar polarityGO:000173630.011
plasma membrane organizationGO:00070091150.011
circadian behaviorGO:004851220.011
reproductive processGO:00224141060.011
behaviorGO:00076101120.011
negative regulation of catabolic processGO:00098951040.011
epithelial cell proliferationGO:00506731280.011
atp metabolic processGO:00460341760.011
oxidation reduction processGO:00551143960.011
single organismal cell cell adhesionGO:00163371480.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
positive regulation of map kinase activityGO:0043406800.011
defense response to other organismGO:00985421290.011
protein acylationGO:00435431380.011
endodermal cell fate commitmentGO:000171140.011
protein localization to nucleusGO:00345041360.011
negative regulation of transferase activityGO:00513481240.011
regulation of nervous system developmentGO:0051960880.011
immune system developmentGO:00025201950.010
calcium ion transportGO:00068161470.010
viral processGO:00160321460.010
positive regulation of immune responseGO:00507781590.010
monocarboxylic acid metabolic processGO:00327871850.010
meiosis iGO:000712740.010
regulation of dephosphorylationGO:0035303960.010
salivary gland morphogenesisGO:000743540.010
circulatory system processGO:00030131130.010
embryonic camera type eye developmentGO:003107620.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
epithelial cell migrationGO:00106311190.010
regulation of metal ion transportGO:00109591200.010
organic hydroxy compound metabolic processGO:19016151470.010
tube morphogenesisGO:0035239950.010
forelimb morphogenesisGO:003513640.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
jnk cascadeGO:0007254800.010
nucleoside monophosphate catabolic processGO:00091251590.010
nucleotide biosynthetic processGO:00091651090.010
positive regulation of cytokine productionGO:00018191670.010
rna splicingGO:00083801310.010
regulation of protein secretionGO:0050708860.010
endodermal cell fate specificationGO:000171440.010
regulation of neurogenesisGO:0050767820.010
peptidyl lysine modificationGO:00182051440.010
positive regulation of ras gtpase activityGO:00323201170.010
positive regulation of synaptic transmissionGO:005080640.010
establishment or maintenance of apical basal cell polarityGO:003508820.010
regulation of cell activationGO:00508651250.010
negative regulation of protein processingGO:00109551420.010
synaptic transmission glycinergicGO:006001210.010

PLEKHG4B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.031
nervous system diseaseDOID:8634310.031
eye diseaseDOID:56141490.025
eye and adnexa diseaseDOID:14921500.025
musculoskeletal system diseaseDOID:172230.023
disease of metabolismDOID:00146672950.023
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
inherited metabolic disorderDOID:6552420.019
organ system cancerDOID:00506861640.019
retinal diseaseDOID:56791180.015
central nervous system diseaseDOID:3311860.015
connective tissue diseaseDOID:651090.014
retinal degenerationDOID:8466890.013
immune system diseaseDOID:29141550.012
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.011
bone diseaseDOID:0080001880.011
neurodegenerative diseaseDOID:12891020.010