Homo sapiens

149 known processes

PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

(Aliases: FLJ46150,DKFZp686C01112,TIGM1,FCYT,ARPKD)

PKHD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.068
cellular amino acid metabolic processGO:00065201160.065
cellular amine metabolic processGO:0044106410.052
regulation of cellular amino acid metabolic processGO:000652160.050
regulation of cellular amine metabolic processGO:0033238110.045
transmembrane transportGO:00550853990.044
regulation of cellular ketone metabolic processGO:0010565500.044
amine metabolic processGO:0009308440.039
cellular ketone metabolic processGO:0042180800.037
multicellular organismal agingGO:001025930.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
positive regulation of cellular amine metabolic processGO:003324070.037
determination of adult lifespanGO:000834020.036
negative regulation of protein metabolic processGO:00512483910.034
sensory perception of smellGO:000760820.034
response to oxygen containing compoundGO:19017003690.032
chemical homeostasisGO:00488783060.032
system processGO:00030083490.031
regulation of proteolysisGO:00301622930.030
anion transportGO:00068201610.030
memoryGO:000761330.030
cellular homeostasisGO:00197251960.030
negative regulation of catalytic activityGO:00430863350.029
negative regulation of cellular protein metabolic processGO:00322693530.029
female gamete generationGO:000729220.029
nitrogen compound transportGO:00717051910.028
regenerationGO:003109940.028
response to abiotic stimulusGO:00096283360.026
oogenesisGO:004847720.026
ion transmembrane transportGO:00342203380.025
biological adhesionGO:00226103310.023
protein processingGO:00164852260.023
cellular response to endogenous stimulusGO:00714953360.023
negative regulation of hydrolase activityGO:00513461820.022
protein maturationGO:00516042330.022
positive regulation of phosphorylationGO:00423273940.022
lipid metabolic processGO:00066293810.022
sensory perceptionGO:00076001030.022
dephosphorylationGO:00163112090.021
defense responseGO:00069523150.021
protein catabolic processGO:00301633250.021
single organism cellular localizationGO:19025803320.021
regulation of endopeptidase activityGO:00525481700.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
neurological system processGO:00508771630.020
immune responseGO:00069553070.020
locomotory behaviorGO:000762610.020
cation transmembrane transportGO:00986552380.020
inorganic ion transmembrane transportGO:00986602310.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
segmentationGO:003528240.020
regulation of cellular response to stressGO:00801352440.020
negative regulation of phosphate metabolic processGO:00459362670.020
ras protein signal transductionGO:0007265730.020
alpha ketoglutarate transportGO:001574210.020
purine ribonucleoside metabolic processGO:00461284370.020
regulation of hormone levelsGO:00108171250.019
organonitrogen compound biosynthetic processGO:19015662000.019
regulation of protein processingGO:00706131500.019
maintenance of locationGO:00512351120.019
single organism carbohydrate metabolic processGO:00447231930.019
negative regulation of phosphorus metabolic processGO:00105632670.019
neuromuscular junction developmentGO:000752830.019
regulation of peptidase activityGO:00525471800.019
carbohydrate derivative biosynthetic processGO:19011372070.019
inorganic cation transmembrane transportGO:00986621940.019
nucleoside triphosphate metabolic processGO:00091414220.019
small molecule biosynthetic processGO:00442831570.019
protein localization to organelleGO:00333652800.019
carbohydrate metabolic processGO:00059752070.019
purine containing compound catabolic processGO:00725234110.018
actin filament based processGO:00300292240.018
small gtpase mediated signal transductionGO:0007264780.018
cellular macromolecule catabolic processGO:00442653800.018
organic anion transportGO:00157111030.018
purine nucleoside triphosphate metabolic processGO:00091444120.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
positive regulation of cellular component organizationGO:00511303760.018
organic acid biosynthetic processGO:0016053970.018
regulation of protein maturationGO:19033171500.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
cellular protein catabolic processGO:00442572610.018
morphogenesis of embryonic epitheliumGO:001633140.018
quorum sensingGO:000937210.018
negative regulation of cellular amine metabolic processGO:003323930.018
positive regulation of catabolic processGO:00098963100.018
spermatid differentiationGO:004851540.018
organophosphate catabolic processGO:00464344300.018
cell adhesionGO:00071553250.018
membrane organizationGO:00610242920.017
secretionGO:00469032540.017
negative regulation of cellular component organizationGO:00511292350.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
regulation of cell cycle processGO:00105642660.017
negative regulation of protein processingGO:00109551420.017
vesicle mediated transportGO:00161923710.017
regulation of reactive oxygen species metabolic processGO:2000377410.017
carboxylic acid biosynthetic processGO:0046394970.017
response to fungusGO:000962040.017
regulation of cell cycleGO:00517263930.017
anatomical structure homeostasisGO:00602491000.017
cellular response to dna damage stimulusGO:00069743790.017
nucleoside triphosphate catabolic processGO:00091433940.017
ion homeostasisGO:00508012300.017
cellular lipid metabolic processGO:00442553030.017
regulation of response to external stimulusGO:00321012220.017
positive regulation of hydrolase activityGO:00513453310.017
cytoplasmic transportGO:00164823790.017
intracellular protein transportGO:00068862700.016
purine nucleotide catabolic processGO:00061954050.016
mitotic cell cycleGO:00002783260.016
positive regulation of protein phosphorylationGO:00019343130.016
negative regulation of apoptotic processGO:00430663160.016
signal transduction by phosphorylationGO:00230142970.016
apoptotic signaling pathwayGO:00971902680.016
regulation of transferase activityGO:00513383550.016
urate transportGO:001574730.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of protein transportGO:00512232130.016
oocyte differentiationGO:000999420.016
positive regulation of transportGO:00510503360.016
positive regulation of cellular catabolic processGO:00313312840.016
circadian behaviorGO:004851220.016
monocarboxylic acid metabolic processGO:00327871850.016
glycosyl compound catabolic processGO:19016584130.016
reactive oxygen species biosynthetic processGO:190340940.016
single organism membrane organizationGO:00448022680.015
regulation of immune responseGO:00507762010.015
negative regulation of protein maturationGO:19033181420.015
nucleotide catabolic processGO:00091664080.015
regulation of kinase activityGO:00435493140.015
photoreceptor cell differentiationGO:004653020.015
oocyte developmentGO:004859910.015
carboxylic acid catabolic processGO:0046395710.015
regulation of cellular component biogenesisGO:00440872810.015
negative regulation of transportGO:00510511760.015
regulation of ion transportGO:00432691890.015
tissue regenerationGO:004224630.015
regulation of establishment of protein localizationGO:00702012420.015
rhythmic behaviorGO:000762220.015
cardiac muscle cell contractionGO:008600340.015
purine ribonucleoside catabolic processGO:00461303980.015
ribonucleoside catabolic processGO:00424544060.015
response to external biotic stimulusGO:00432072610.015
metal ion transportGO:00300012720.015
innate immune responseGO:00450871780.015
regulation of cell differentiationGO:00455953930.015
cellular response to oxygen containing compoundGO:19017012760.015
protein targetingGO:00066051870.015
regulation of protein kinase activityGO:00458592890.015
organic hydroxy compound metabolic processGO:19016151470.015
spermatid developmentGO:000728640.015
regulation of protein localizationGO:00328802960.015
cellular chemical homeostasisGO:00550821800.015
reactive oxygen species metabolic processGO:0072593750.015
cell morphogenesisGO:00009022960.014
wnt signaling pathwayGO:00160551560.014
cation transportGO:00068123310.014
ribonucleotide catabolic processGO:00092614050.014
growthGO:00400072020.014
cellular response to hydroxyisoflavoneGO:007141310.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
negative regulation of multicellular organismal processGO:00512413170.014
protein modification by small protein conjugationGO:00324463420.014
embryonic epithelial tube formationGO:000183840.014
negative regulation of protein modification processGO:00314002000.014
negative regulation of intracellular signal transductionGO:19025321830.014
detection of chemical stimulus involved in sensory perceptionGO:0050907330.014
anterior posterior axis specificationGO:000994820.014
response to hormoneGO:00097251750.014
associative learningGO:000830610.014
purine ribonucleotide catabolic processGO:00091544040.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
cellular macromolecular complex assemblyGO:00346223240.014
cell fate determinationGO:000170930.014
reactive nitrogen species metabolic processGO:200105730.014
lipid biosynthetic processGO:00086101770.014
small molecule catabolic processGO:0044282920.014
rho protein signal transductionGO:0007266260.014
nervous system developmentGO:00073992930.014
blastoderm segmentationGO:000735020.014
mitotic cell cycle processGO:19030472860.014
purine nucleoside catabolic processGO:00061523980.014
nucleoside phosphate catabolic processGO:19012924120.014
regulation of cellular component movementGO:00512703340.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
cell projection organizationGO:00300302520.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of nucleotide metabolic processGO:00061402690.014
detection of chemical stimulus involved in sensory perception of smellGO:005091120.013
response to organic cyclic compoundGO:00140702040.013
atp metabolic processGO:00460341760.013
response to other organismGO:00517072610.013
inner ear morphogenesisGO:004247240.013
interspecies interaction between organismsGO:00444191560.013
regulation of anatomical structure morphogenesisGO:00226032860.013
cellular ion homeostasisGO:00068731680.013
negative regulation of cell proliferationGO:00082852280.013
secretion by cellGO:00329402260.013
response to biotic stimulusGO:00096072760.013
hindbrain developmentGO:003090230.013
negative regulation of proteolysisGO:00458611320.013
positive regulation of cell deathGO:00109422630.013
detection of stimulusGO:0051606850.013
posttranscriptional regulation of gene expressionGO:00106082130.013
glycoprotein metabolic processGO:00091001100.013
organic acid catabolic processGO:0016054710.013
regulation of intracellular transportGO:00323861950.013
cation homeostasisGO:00550801890.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of wnt signaling pathwayGO:00301111230.013
limbic system developmentGO:002176130.013
negative regulation of phosphorylationGO:00423261740.013
cell growthGO:00160491600.013
regulation of purine nucleotide metabolic processGO:19005422640.013
tripartite regional subdivisionGO:000735120.013
positive regulation of immune system processGO:00026842830.013
sodium dependent organic cation transportGO:007071510.013
nucleocytoplasmic transportGO:00069131760.013
rna processingGO:00063962550.013
regulation of protein catabolic processGO:00421761550.012
adult locomotory behaviorGO:000834410.012
positive regulation of nucleotide metabolic processGO:00459812300.012
primary neural tube formationGO:001402030.012
tube closureGO:006060630.012
nuclear transportGO:00511691790.012
proteasomal protein catabolic processGO:00104981760.012
actin mediated cell contractionGO:0070252120.012
anterior posterior axis specification embryoGO:000859520.012
regulation of secretionGO:00510461940.012
defense response to fungusGO:005083240.012
multi organism cellular processGO:00447641560.012
modification dependent macromolecule catabolic processGO:00436322120.012
compound eye developmentGO:004874910.012
nucleoside catabolic processGO:00091644080.012
neural tube formationGO:000184130.012
negative regulation of cell deathGO:00605483450.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
cell divisionGO:00513011680.012
actin filament based movementGO:0030048170.012
positive regulation of apoptotic processGO:00430652460.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
negative regulation of peptidase activityGO:0010466910.012
negative regulation of endopeptidase activityGO:0010951840.012
protein ubiquitinationGO:00165673140.012
response to lipidGO:00339932060.012
sleepGO:003043120.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
regulation of secretion by cellGO:19035301770.012
coenzyme metabolic processGO:0006732650.012
regulation of meiotic cell cycleGO:005144540.012
microtubule based processGO:00070172100.012
cellular response to growth factor stimulusGO:00713631970.012
regulation of locomotionGO:00400123290.012
activation of immune responseGO:00022531140.012
sodium independent organic anion transportGO:004325220.012
hormone transportGO:0009914680.012
alpha amino acid metabolic processGO:1901605720.012
cellular response to abiotic stimulusGO:00712141170.012
cellular protein complex assemblyGO:00436231880.012
positive regulation of cellular component biogenesisGO:00440891580.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
regulation of cytokine productionGO:00018172320.011
cell cycle phase transitionGO:00447701730.011
circulatory system developmentGO:00723592620.011
response to inorganic substanceGO:00100351270.011
establishment of protein localization to organelleGO:00725941720.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
metal ion homeostasisGO:00550651690.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
positive regulation of secretionGO:00510471160.011
regulation of apoptotic signaling pathwayGO:20012331750.011
regulation of growthGO:00400081650.011
monovalent inorganic cation transportGO:00156721280.011
modification dependent protein catabolic processGO:00199412090.011
response to growth factorGO:00708482050.011
canonical wnt signaling pathwayGO:00600701160.011
chromatin modificationGO:00165682980.011
organophosphate biosynthetic processGO:00904071630.011
anion transmembrane transportGO:0098656760.011
positive regulation of proteolysisGO:00458621420.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
positive regulation of programmed cell deathGO:00430682490.011
carboxylic acid transportGO:0046942630.011
regulation of cytoskeleton organizationGO:00514931770.011
cellular response to hormone stimulusGO:00328701250.011
cell projection assemblyGO:00300311260.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
mitochondrion organizationGO:00070051560.011
regulation of cytoplasmic transportGO:19036491490.011
regulation of dephosphorylationGO:0035303960.011
meiosis iGO:000712740.011
detection of chemical stimulusGO:0009593550.011
quorum sensing involved in interaction with hostGO:005210610.011
ubiquitin dependent protein catabolic processGO:00065112060.011
purine containing compound biosynthetic processGO:0072522880.011
protein localization to nucleusGO:00345041360.011
regulation of defense responseGO:00313471540.011
melanin metabolic processGO:000658210.011
cellular response to lipidGO:00713961270.011
monocarboxylic acid biosynthetic processGO:0072330670.011
nucleoside monophosphate catabolic processGO:00091251590.011
meiotic chromosome segregationGO:004513240.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
epithelial cell proliferationGO:00506731280.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
syncytium formation by plasma membrane fusionGO:000076820.011
protein autophosphorylationGO:00467771230.011
somitogenesisGO:000175620.011
negative regulation of transferase activityGO:00513481240.011
negative regulation of protein phosphorylationGO:00019331400.011
regulation of actin filament based processGO:00329701410.011
actin cytoskeleton organizationGO:00300362070.011
negative regulation of developmental processGO:00510932470.011
chromatin organizationGO:00063253510.011
negative regulation of cell cycleGO:00457861930.011
epithelium developmentGO:00604292270.011
positive regulation of transferase activityGO:00513472270.011
positive regulation of cell migrationGO:00303351720.010
response to radiationGO:00093141510.010
oxidation reduction processGO:00551143960.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
regulation of body fluid levelsGO:0050878990.010
regulation of intracellular protein transportGO:00331571230.010
blastocyst developmentGO:000182430.010
cell cell signalingGO:00072671550.010
response to oxidative stressGO:00069791210.010
mapk cascadeGO:00001652880.010
positive regulation of immune responseGO:00507781590.010
lipid transportGO:0006869900.010
regulation of cell migrationGO:00303342890.010
regulation of homeostatic processGO:00328441210.010
cellular lipid catabolic processGO:0044242650.010
response to drugGO:0042493810.010
regulation of cell motilityGO:20001452990.010
regulation of mapk cascadeGO:00434082620.010
organ formationGO:004864530.010
regulation of branching involved in ureteric bud morphogenesisGO:009018930.010
cellular component morphogenesisGO:00329893140.010
positive regulation of kinase activityGO:00336742040.010
long term memoryGO:000761620.010
positive regulation of locomotionGO:00400171860.010
response to woundingGO:00096111680.010
metencephalon developmentGO:002203720.010

PKHD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.045
inherited metabolic disorderDOID:6552420.037
sensory system diseaseDOID:00501552030.032
nervous system diseaseDOID:8634310.032
eye and adnexa diseaseDOID:14921500.024
eye diseaseDOID:56141490.024
retinal diseaseDOID:56791180.017
retinal degenerationDOID:8466890.016
central nervous system diseaseDOID:3311860.015
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
immune system diseaseDOID:29141550.012
musculoskeletal system diseaseDOID:172230.012
amino acid metabolic disorderDOID:9252500.011
urinary system diseaseDOID:18400.010
hematopoietic system diseaseDOID:741000.010
polycystic kidney diseaseDOID:89830.000