Homo sapiens

67 known processes

CBX8

chromobox homolog 8

(Aliases: PC3,RC1)

CBX8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h2a monoubiquitinationGO:0035518110.999
histone h2a ubiquitinationGO:0033522170.999
histone monoubiquitinationGO:0010390200.999
protein modification by small protein conjugationGO:00324463420.992
Mouse
histone ubiquitinationGO:0016574310.987
Mouse
regulation of axon guidanceGO:190266730.981
regulation of axon extension involved in axon guidanceGO:004884120.935
chromatin organizationGO:00063253510.921
Mouse
protein monoubiquitinationGO:0006513390.910
chromatin modificationGO:00165682980.907
Mouse
positive regulation of ligase activityGO:0051351190.875
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.838
positive regulation of transferase activityGO:00513472270.802
positive regulation of ubiquitin protein transferase activityGO:0051443180.763
covalent chromatin modificationGO:00165692540.746
Mouse
protein ubiquitinationGO:00165673140.741
Mouse
histone modificationGO:00165702510.741
Mouse
fibroblast proliferationGO:0048144330.703
blastoderm segmentationGO:000735020.689
Fly
spinal cord developmentGO:002151040.662
regulation of protein ubiquitinationGO:0031396950.611
response to radiationGO:00093141510.583
Fly
gene silencingGO:0016458490.567
Fly
anterior posterior axis specificationGO:000994820.559
positive regulation of fibroblast proliferationGO:0048146210.554
regulation of ubiquitin protein transferase activityGO:0051438280.458
generation of neuronsGO:00486991520.448
Fly
regulation of ligase activityGO:0051340290.425
nervous system developmentGO:00073992930.395
Fly
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.361
hemopoiesisGO:00300971800.360
embryo developmentGO:00097901230.317
Fly
response to abiotic stimulusGO:00096283360.316
Fly
regulation of transferase activityGO:00513383550.311
regulation of nervous system developmentGO:0051960880.306
positive regulation of cell proliferationGO:00082843010.291
immune system developmentGO:00025201950.286
cell developmentGO:00484683280.286
Fly
skeletal system developmentGO:0001501790.283
neurogenesisGO:00220081690.279
Fly
response to oxygen containing compoundGO:19017003690.264
organ morphogenesisGO:00098871470.244
response to woundingGO:00096111680.230
Fly
cellular component morphogenesisGO:00329893140.224
hematopoietic or lymphoid organ developmentGO:00485341860.224
regulation of fibroblast proliferationGO:0048145320.223
regulation of neuron differentiationGO:0045664700.214
mitotic cell cycleGO:00002783260.213
Fly
post embryonic developmentGO:000979120.210
response to ionizing radiationGO:0010212650.208
Fly
regulation of cell differentiationGO:00455953930.206
cellular macromolecule catabolic processGO:00442653800.201
histone acetylationGO:0016573930.195
response to lipidGO:00339932060.192
neuron differentiationGO:00301821380.186
Fly
neuron projection developmentGO:00311751060.182
embryonic morphogenesisGO:0048598850.166
negative regulation of apoptotic signaling pathwayGO:2001234970.160
cell morphogenesisGO:00009022960.157
axon extension involved in axon guidanceGO:004884650.153
neuron developmentGO:00486661130.141
Fly
cell projection organizationGO:00300302520.137
negative regulation of cell deathGO:00605483450.136
regulation of extent of cell growthGO:006138790.135
cellular response to growth factor stimulusGO:00713631970.135
regulation of cell projection organizationGO:00313441070.134
regulation of protein modification by small protein conjugation or removalGO:19033201070.134
regulation of neurogenesisGO:0050767820.129
cellular response to oxidative stressGO:0034599850.127
regionalizationGO:0003002290.115
Fly
chemotaxisGO:00069351570.111
axon developmentGO:0061564340.111
regulation of apoptotic signaling pathwayGO:20012331750.109
regulation of locomotionGO:00400123290.107
rostrocaudal neural tube patterningGO:002190310.106
regulation of gene expression epigeneticGO:0040029730.098
digestive tract developmentGO:0048565750.093
regulation of cell developmentGO:00602841610.092
cell projection morphogenesisGO:00488581290.090
hindbrain developmentGO:003090230.087
regulation of chemotaxisGO:0050920740.086
negative regulation of gene expression epigeneticGO:0045814190.086
central nervous system neuron developmentGO:002195470.085
peptidyl lysine modificationGO:00182051440.080
positive regulation of cellular catabolic processGO:00313312840.076
response to organic cyclic compoundGO:00140702040.075
tube morphogenesisGO:0035239950.075
cellular amino acid metabolic processGO:00065201160.075
tube developmentGO:00352951250.072
axon extensionGO:0048675130.071
embryonic skeletal system developmentGO:0048706130.070
anatomical structure formation involved in morphogenesisGO:00486462840.067
neuron projection morphogenesisGO:0048812500.064
embryonic organ morphogenesisGO:0048562240.062
metencephalon developmentGO:002203720.061
neuron fate commitmentGO:004866320.061
regulation of cell motilityGO:20001452990.060
axon regenerationGO:003110310.060
skeletal system morphogenesisGO:0048705240.059
negative regulation of programmed cell deathGO:00430693210.057
regulation of growthGO:00400081650.057
enzyme linked receptor protein signaling pathwayGO:00071673030.057
axonogenesisGO:0007409310.056
protein deubiquitinationGO:0016579790.055
stem cell developmentGO:0048864690.053
reproductive processGO:00224141060.052
Human
chromosome segregationGO:00070591140.051
gastrulation with mouth forming secondGO:000170210.051
purine nucleotide catabolic processGO:00061954050.050
response to retinoic acidGO:0032526330.050
specification of organ identityGO:001009230.050
embryonic cranial skeleton morphogenesisGO:004870160.050
positive regulation of cellular amino acid metabolic processGO:004576430.050
proteolysis involved in cellular protein catabolic processGO:00516032440.049
positive regulation of protein ubiquitinationGO:0031398530.048
bmp signaling pathwayGO:0030509490.048
internal peptidyl lysine acetylationGO:0018393970.048
regulation of response to external stimulusGO:00321012220.048
neuromuscular junction developmentGO:000752830.047
cellular response to oxygen containing compoundGO:19017012760.047
apoptotic signaling pathwayGO:00971902680.046
negative regulation of cellular protein metabolic processGO:00322693530.045
embryonic organ developmentGO:0048568360.045
cellular response to decreased oxygen levelsGO:0036294510.045
regulation of tooth mineralizationGO:007017030.043
ubiquitin dependent protein catabolic processGO:00065112060.043
modification dependent protein catabolic processGO:00199412090.043
neuron projection regenerationGO:003110210.042
negative regulation of apoptotic processGO:00430663160.042
negative regulation of intracellular signal transductionGO:19025321830.042
taxisGO:00423301570.041
regulation of neuron projection developmentGO:0010975570.041
cellular response to hydrogen peroxideGO:0070301370.040
chromatin silencingGO:0006342120.040
cell divisionGO:00513011680.040
digestive system developmentGO:0055123750.040
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.039
camera type eye developmentGO:0043010250.039
response to acid chemicalGO:0001101660.039
cellular protein catabolic processGO:00442572610.039
embryonic skeletal system morphogenesisGO:004870490.038
negative regulation of developmental processGO:00510932470.038
regulation of chondrocyte differentiationGO:003233090.038
response to alcoholGO:0097305640.038
positive regulation of cellular amine metabolic processGO:003324070.037
negative regulation of protein metabolic processGO:00512483910.037
protein catabolic processGO:00301633250.037
rna processingGO:00063962550.036
nucleotide catabolic processGO:00091664080.036
t cell differentiation in thymusGO:003307740.036
response to inorganic substanceGO:00100351270.036
organ formationGO:004864530.035
mrna metabolic processGO:00160711750.035
developmental cell growthGO:0048588180.035
cardiovascular system developmentGO:00723582620.035
immature t cell proliferation in thymusGO:003308010.035
peptidyl lysine acetylationGO:00183941010.034
cell junction organizationGO:0034330790.034
central nervous system developmentGO:00074171230.034
nucleoside triphosphate catabolic processGO:00091433940.034
cellular response to endogenous stimulusGO:00714953360.034
regulation of nucleotide catabolic processGO:00308112050.034
regulation of neuron projection regenerationGO:007057010.033
regulation of cell migrationGO:00303342890.033
cellular macromolecular complex assemblyGO:00346223240.033
multicellular organismal agingGO:001025930.033
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.032
wound healingGO:00420601150.031
Fly
neuron projection guidanceGO:0097485120.031
negative regulation of chromosome organizationGO:2001251480.031
amine metabolic processGO:0009308440.030
regulation of cellular amino acid metabolic processGO:000652160.030
cell fate determinationGO:000170930.030
positive regulation of cell differentiationGO:00455972110.030
regulation of multi organism processGO:00439001570.029
growthGO:00400072020.029
intrinsic apoptotic signaling pathwayGO:00971931270.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
small gtpase mediated signal transductionGO:0007264780.029
mitotic cell cycle checkpointGO:0007093680.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
chordate embryonic developmentGO:0043009340.029
response to endoplasmic reticulum stressGO:0034976490.029
positive regulation of catabolic processGO:00098963100.029
cartilage developmentGO:0051216310.029
cellular response to acid chemicalGO:0071229440.029
axon guidanceGO:0007411120.029
protein acylationGO:00435431380.028
lipid metabolic processGO:00066293810.028
response to axon injuryGO:004867810.028
regenerationGO:003109940.027
regulation of cellular ketone metabolic processGO:0010565500.026
cell growthGO:00160491600.026
limbic system developmentGO:002176130.026
regulation of cellular amine metabolic processGO:0033238110.026
regulation of axonogenesisGO:0050770160.026
regulation of cellular response to stressGO:00801352440.025
regulation of cellular component movementGO:00512703340.025
posttranscriptional regulation of gene expressionGO:00106082130.025
pathway restricted smad protein phosphorylationGO:0060389380.025
neuron projection extensionGO:1990138140.025
positive regulation of response to external stimulusGO:0032103880.025
negative regulation of phosphate metabolic processGO:00459362670.024
cell morphogenesis involved in neuron differentiationGO:0048667440.024
negative regulation of cell differentiationGO:00455961710.024
cellular response to hypoxiaGO:0071456510.024
purine ribonucleoside catabolic processGO:00461303980.024
rna splicing via transesterification reactionsGO:0000375900.024
positive regulation of hormone biosynthetic processGO:004688640.024
motor neuron axon guidanceGO:000804520.024
cell proliferation in forebrainGO:002184610.024
peripheral nervous system developmentGO:000742220.023
cell substrate adhesionGO:00315891320.023
cellular response to transforming growth factor beta stimulusGO:0071560940.023
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.023
negative regulation of catalytic activityGO:00430863350.023
humoral immune responseGO:0006959490.023
appendage developmentGO:0048736230.023
negative regulation of phosphorus metabolic processGO:00105632670.023
neuron projection extension involved in neuron projection guidanceGO:190228450.023
epithelial cell proliferationGO:00506731280.023
epithelium developmentGO:00604292270.023
regulation of anatomical structure sizeGO:00900661010.023
pituitary gland developmentGO:002198320.022
photoreceptor cell differentiationGO:004653020.022
locomotory behaviorGO:000762610.022
cell differentiation in spinal cordGO:002151510.022
rna splicingGO:00083801310.022
positive regulation of nucleoside metabolic processGO:00459791860.022
cellular ketone metabolic processGO:0042180800.021
cellular amine metabolic processGO:0044106410.021
vesicle mediated transportGO:00161923710.021
negative regulation of multicellular organismal processGO:00512413170.021
response to oxidative stressGO:00069791210.021
single organism membrane organizationGO:00448022680.021
negative regulation of cellular component organizationGO:00511292350.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
response to growth factorGO:00708482050.021
negative regulation of organelle organizationGO:00106391260.020
morphogenesis of a polarized epitheliumGO:000173830.020
regulation of cell cycle processGO:00105642660.020
neuron remodelingGO:001632220.020
Fly
regulation of cell morphogenesisGO:00226041530.020
determination of adult lifespanGO:000834020.020
matingGO:000761810.020
cellular lipid metabolic processGO:00442553030.020
mrna processingGO:00063971330.020
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.020
regulation of protein stabilityGO:0031647870.020
transforming growth factor beta receptor signaling pathwayGO:0007179760.020
negative regulation of catabolic processGO:00098951040.020
positive regulation of apoptotic processGO:00430652460.020
positive regulation of proteolysisGO:00458621420.020
prostate gland developmentGO:003085030.019
dna repairGO:00062811980.019
sex differentiationGO:0007548450.019
Human
actin mediated cell contractionGO:0070252120.019
regulation of kinase activityGO:00435493140.019
female gamete generationGO:000729220.019
dephosphorylationGO:00163112090.019
development of primary sexual characteristicsGO:0045137350.019
Human
regulation of wnt signaling pathwayGO:00301111230.019
oogenesisGO:004847720.019
single organism cellular localizationGO:19025803320.019
tissue morphogenesisGO:0048729960.019
forebrain developmentGO:0030900260.019
regulation of proteolysisGO:00301622930.019
regulation of dna metabolic processGO:00510521530.019
response to decreased oxygen levelsGO:0036293960.019
rho protein signal transductionGO:0007266260.019
purine ribonucleoside metabolic processGO:00461284370.019
cerebellum developmentGO:002154920.018
positive regulation of programmed cell deathGO:00430682490.018
regulation of cell growthGO:00015581350.018
cell cycle checkpointGO:00000751170.018
organ inductionGO:000175940.018
regulation of cytokine productionGO:00018172320.018
positive regulation of developmental processGO:00510943140.018
regulation of anatomical structure morphogenesisGO:00226032860.018
nerve developmentGO:002167540.018
regulation of cellular component sizeGO:0032535820.018
negative regulation of cell adhesionGO:0007162640.018
nucleoside phosphate catabolic processGO:19012924120.018
digestive tract morphogenesisGO:0048546560.018
sister chromatid cohesionGO:0007062240.018
inner ear morphogenesisGO:004247240.018
myoblast fusionGO:000752010.018
reproductionGO:0000003630.017
small molecule biosynthetic processGO:00442831570.017
anterior posterior pattern specificationGO:000995290.017
forebrain regionalizationGO:002187130.017
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.017
pattern specification processGO:0007389430.017
Fly
nucleotide excision repairGO:0006289310.017
bone mineralizationGO:0030282340.017
positive regulation of mitotic cell cycleGO:0045931600.017
actin filament based processGO:00300292240.017
somatic stem cell maintenanceGO:003501940.017
positive regulation of immune system processGO:00026842830.017
mitochondrion organizationGO:00070051560.017
organelle fissionGO:00482851490.017
actin cytoskeleton organizationGO:00300362070.017
heart developmentGO:0007507950.017
guanosine containing compound catabolic processGO:19010692390.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
negative regulation of hydrolase activityGO:00513461820.016
regulation of nucleoside metabolic processGO:00091182090.016
mitotic cell cycle processGO:19030472860.016
cell morphogenesis involved in differentiationGO:00009041440.016
adult locomotory behaviorGO:000834410.016
stem cell differentiationGO:0048863930.016
regulation of axon regenerationGO:004867910.016
regulation of protein kinase activityGO:00458592890.016
head developmentGO:00603221080.016
signal transduction by p53 class mediatorGO:0072331720.016
positive regulation of nucleotide metabolic processGO:00459812300.016
stem cell divisionGO:001714520.016
cell junction assemblyGO:0034329670.016
positive regulation of cell deathGO:00109422630.016
regulation of meiotic cell cycleGO:005144540.016
regulation of behaviorGO:0050795820.015
response to ketoneGO:1901654190.015
primary neural tube formationGO:001402030.015
regulation of epithelial cell proliferationGO:00506781130.015
embryonic forelimb morphogenesisGO:003511540.015
regulation of odontogenesisGO:004248140.015
regulation of protein bindingGO:0043393660.015
negative regulation of translationGO:0017148370.015
immune responseGO:00069553070.015
positive regulation of hydrolase activityGO:00513453310.015
chondrocyte differentiationGO:0002062170.015
internal protein amino acid acetylationGO:00064751010.015
nucleoside catabolic processGO:00091644080.015
negative regulation of protein modification processGO:00314002000.015
retinal ganglion cell axon guidanceGO:003129020.015
regulation of synaptic plasticityGO:004816730.015
behaviorGO:00076101120.015
regulation of establishment of protein localizationGO:00702012420.014
regulation of cartilage developmentGO:0061035120.014
embryonic hemopoiesisGO:003516240.014
ribonucleoside triphosphate metabolic processGO:00091994120.014
protein methylationGO:0006479740.014
syncytium formation by plasma membrane fusionGO:000076820.014
positive regulation of cellular component organizationGO:00511303760.014
protein acetylationGO:00064731160.014
positive regulation of protein transportGO:00512221350.014
negative regulation of cell cycleGO:00457861930.014
regulation of heart induction by regulation of canonical wnt signaling pathwayGO:009008110.014
cellular response to reactive oxygen speciesGO:0034614500.014
cardiac right ventricle morphogenesisGO:000321530.014
regulation of bindingGO:00510981110.014
nuclear divisionGO:00002801280.014
cranial nerve developmentGO:002154540.013
nuclear transportGO:00511691790.013
organic acid biosynthetic processGO:0016053970.013
circulatory system developmentGO:00723592620.013
negative regulation of cell proliferationGO:00082852280.013
regulation of signal transduction by p53 class mediatorGO:1901796260.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
positive regulation of cysteine type endopeptidase activityGO:2001056790.013
response to gamma radiationGO:0010332140.013
Fly
positive regulation of protein phosphorylationGO:00019343130.013
ventral spinal cord developmentGO:002151710.013
purine nucleoside catabolic processGO:00061523980.013
protein localization to organelleGO:00333652800.013
establishment of tissue polarityGO:000716430.013
cell cell junction organizationGO:0045216690.013
eye morphogenesisGO:0048592160.013
leukocyte differentiationGO:0002521980.013
response to hormoneGO:00097251750.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.013
regulation of t cell activationGO:0050863770.013
regulation of protein catabolic processGO:00421761550.013
response to transforming growth factor betaGO:0071559940.013
morphogenesis of embryonic epitheliumGO:001633140.013
purine nucleoside triphosphate metabolic processGO:00091444120.013
cell adhesionGO:00071553250.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
positive regulation of protein complex assemblyGO:0031334860.013
glycosyl compound catabolic processGO:19016584130.013
translationGO:00064121320.013
regulation of gtpase activityGO:00430871800.013
blastocyst formationGO:000182530.013
protein processingGO:00164852260.013
protein localization to cell surfaceGO:0034394280.012
negative regulation of mitotic cell cycleGO:00459301020.012
positive regulation of phosphorylationGO:00423273940.012
cellular response to organonitrogen compoundGO:00714171240.012
negative regulation of cell motilityGO:20001461040.012
neurotransmitter secretionGO:000726940.012
monoubiquitinated protein deubiquitinationGO:003552060.012
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.012
regulation of t cell differentiation in thymusGO:003308120.012
negative regulation of cellular catabolic processGO:0031330830.012
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.012
hippocampus developmentGO:002176610.012
single organism reproductive processGO:0044702980.012
negative regulation of muscle contractionGO:004593230.012
regulation of endopeptidase activityGO:00525481700.012
autophagyGO:0006914880.012
purine ribonucleotide catabolic processGO:00091544040.012
embryonic camera type eye morphogenesisGO:004859620.012
cellular response to hormone stimulusGO:00328701250.012
neuroblast proliferationGO:000740540.012
cellular response to abiotic stimulusGO:00712141170.012
regulation of protein transportGO:00512232130.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
double strand break repairGO:00063021010.012
regulation of protein localizationGO:00328802960.012
mrna splicing via spliceosomeGO:0000398890.012
regulation of response to woundingGO:19030341010.012
proteasomal protein catabolic processGO:00104981760.012
negative regulation of gliogenesisGO:001401430.012
regulation of organ formationGO:000315640.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
neuroendocrine cell differentiationGO:006110120.012
developmental maturationGO:0021700280.012
Fly
positive regulation of protein kinase activityGO:00458601900.011
single organism cell adhesionGO:00986021790.011
regulation of cell adhesionGO:00301551660.011
establishment of nucleus localizationGO:004002310.011
vasculature developmentGO:00019441810.011
somatic muscle developmentGO:000752510.011
protein sumoylationGO:0016925250.011
cellular response to peptide hormone stimulusGO:0071375560.011
sex determinationGO:000753030.011
establishment of protein localization to membraneGO:00901501210.011
cellular response to oxygen levelsGO:0071453550.011
myosin filament assemblyGO:003103420.011
membrane organizationGO:00610242920.011
positive regulation of cell cycleGO:00457871400.011
maintenance of locationGO:00512351120.011
cardiac cell fate determinationGO:006091330.011
regulation of male gonad developmentGO:200001840.011
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.011
cell substrate junction assemblyGO:0007044350.011
negative regulation of cellular amine metabolic processGO:003323930.011
soft palate developmentGO:006002330.011
gastrulationGO:0007369510.011
heart formationGO:006091420.011
regulation of atp catabolic processGO:1903289250.011
mesenchymal cell developmentGO:0014031500.011
oocyte differentiationGO:000999420.011
negative regulation of locomotionGO:00400131180.011
regulation of protein complex assemblyGO:00432541470.011
non canonical wnt signaling pathway via mapk cascadeGO:003803040.011
ribonucleotide catabolic processGO:00092614050.010
lipid biosynthetic processGO:00086101770.010
regulation of organ morphogenesisGO:2000027240.010
neuronal action potentialGO:001922890.010
wnt signaling pathwayGO:00160551560.010
ion homeostasisGO:00508012300.010
endothelial cell migrationGO:0043542860.010
endomembrane system organizationGO:00102561960.010
outflow tract septum morphogenesisGO:000314840.010
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.010
signal transduction in response to dna damageGO:0042770570.010
embryo development ending in birth or egg hatchingGO:0009792340.010
camera type eye morphogenesisGO:0048593120.010
regulation of mapk cascadeGO:00434082620.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
cellular response to peptideGO:1901653590.010
blastocyst developmentGO:000182430.010
cation transmembrane transportGO:00986552380.010
striated muscle myosin thick filament assemblyGO:007168820.010

CBX8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.032
eye diseaseDOID:56141490.032
sensory system diseaseDOID:00501552030.032
eye and adnexa diseaseDOID:14921500.032
disease of metabolismDOID:00146672950.021
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
organ system cancerDOID:00506861640.018
musculoskeletal system diseaseDOID:172230.017
connective tissue diseaseDOID:651090.016
bone diseaseDOID:0080001880.014
neurodegenerative diseaseDOID:12891020.012
central nervous system diseaseDOID:3311860.012
neuropathyDOID:870520.012
heart diseaseDOID:114680.011
cardiovascular system diseaseDOID:12871060.011
bone development diseaseDOID:0080006550.011
osteochondrodysplasiaDOID:2256350.010