Homo sapiens

256 known processes

NLRP3

NLR family, pyrin domain containing 3

(Aliases: MWS,AGTAVPRL,CLR1.1,CIAS1,FCU,FCAS,C1orf7,AVP,NALP3,AII,AII/AVP,FLJ95925,PYPAF1)

NLRP3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytokine productionGO:00018162470.578
immune responseGO:00069553070.398
Human
regulation of secretion by cellGO:19035301770.390
regulation of cytokine productionGO:00018172320.380
defense responseGO:00069523150.379
positive regulation of cell proliferationGO:00082843010.379
positive regulation of immune system processGO:00026842830.367
Human
regulation of immune responseGO:00507762010.365
Human
regulation of protein secretionGO:0050708860.319
response to biotic stimulusGO:00096072760.314
cell activationGO:00017752130.308
Human
cellular response to molecule of bacterial originGO:0071219620.294
regulation of defense responseGO:00313471540.294
secretionGO:00469032540.281
response to other organismGO:00517072610.273
regulation of response to external stimulusGO:00321012220.271
innate immune responseGO:00450871780.270
Human
mononuclear cell proliferationGO:0032943710.259
vesicle mediated transportGO:00161923710.253
regulation of t cell activationGO:0050863770.250
cd8 positive alpha beta t cell activationGO:003603730.242
positive regulation of immune responseGO:00507781590.239
Human
regulation of leukocyte migrationGO:0002685630.235
positive regulation of phosphorylationGO:00423273940.228
Human
regulation of lymphocyte proliferationGO:0050670640.225
positive regulation of cytokine productionGO:00018191670.223
positive regulation of programmed cell deathGO:00430682490.220
regulation of secretionGO:00510461940.217
regulation of multi organism processGO:00439001570.217
regulation of cd8 positive alpha beta t cell activationGO:200118520.212
response to external biotic stimulusGO:00432072610.209
negative regulation of alpha beta t cell activationGO:004663630.209
negative regulation of cytokine productionGO:0001818820.203
g protein coupled receptor signaling pathwayGO:00071862070.202
regulation of cytokine secretionGO:0050707570.192
regulation of leukocyte activationGO:00026941150.185
Human
immune response regulating signaling pathwayGO:0002764970.185
Human
regulation of cell activationGO:00508651250.185
Human
cation transportGO:00068123310.182
immune effector processGO:00022521590.182
Human Mouse
positive regulation of leukocyte proliferationGO:0070665480.179
positive regulation of hydrolase activityGO:00513453310.176
small gtpase mediated signal transductionGO:0007264780.173
mapk cascadeGO:00001652880.172
Human
positive regulation of apoptotic processGO:00430652460.171
response to oxygen containing compoundGO:19017003690.170
response to lipidGO:00339932060.169
cellular response to oxygen containing compoundGO:19017012760.169
regulation of immune effector processGO:0002697910.168
regulation of interferon beta productionGO:0032648220.167
regulation of t cell proliferationGO:0042129420.167
protein secretionGO:0009306980.165
secretion by cellGO:00329402260.164
interleukin 12 secretionGO:007261010.164
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.163
Human
cell adhesionGO:00071553250.161
regulation of mononuclear cell proliferationGO:0032944650.161
regulation of locomotionGO:00400123290.159
cellular response to lipopolysaccharideGO:0071222570.159
positive regulation of erk1 and erk2 cascadeGO:0070374750.156
regulation of cellular amine metabolic processGO:0033238110.156
regulation of protein localizationGO:00328802960.154
biological adhesionGO:00226103310.152
leukocyte migrationGO:00509001070.151
regulation of innate immune responseGO:0045088970.149
Human
calcium ion transportGO:00068161470.145
t cell activationGO:0042110990.145
Human
leukocyte proliferationGO:0070661740.139
negative regulation of cell proliferationGO:00082852280.138
positive regulation of cell deathGO:00109422630.138
metal ion transportGO:00300012720.137
positive regulation of mononuclear cell proliferationGO:0032946470.137
defense response to other organismGO:00985421290.135
Human Mouse
regulation of protein transportGO:00512232130.134
positive regulation of protein phosphorylationGO:00019343130.133
regulation of ion transportGO:00432691890.133
lymphocyte proliferationGO:0046651700.133
negative regulation of cd8 positive alpha beta t cell activationGO:200118610.132
defense response to virusGO:0051607710.129
Human Mouse
cellular amino acid metabolic processGO:00065201160.129
regulation of establishment of protein localizationGO:00702012420.126
response to bacteriumGO:00096171440.125
lymphocyte activationGO:00466491330.123
Human
signal transduction by phosphorylationGO:00230142970.123
Human
regulation of mapk cascadeGO:00434082620.123
Human
regulation of leukocyte proliferationGO:0070663670.121
ras protein signal transductionGO:0007265730.121
positive regulation of t cell proliferationGO:0042102330.119
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:200118910.119
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.118
negative regulation of multicellular organismal processGO:00512413170.118
positive regulation of lymphocyte proliferationGO:0050671460.117
divalent metal ion transportGO:00708381520.115
negative regulation of protein metabolic processGO:00512483910.114
Human
positive regulation of lymphocyte activationGO:0051251730.113
Human
actin filament based processGO:00300292240.113
regulation of interleukin 10 secretionGO:200117940.110
cellular amine metabolic processGO:0044106410.108
positive regulation of cell activationGO:0050867810.105
Human
leukocyte activationGO:00453211640.104
Human
leukocyte activation involved in immune responseGO:0002366300.103
regulation of erk1 and erk2 cascadeGO:0070372990.102
single organism cell adhesionGO:00986021790.101
rho protein signal transductionGO:0007266260.100
regulation of cellular amino acid metabolic processGO:000652160.100
regulation of metal ion transportGO:00109591200.099
negative regulation of cell deathGO:00605483450.099
cellular response to biotic stimulusGO:0071216710.097
positive regulation of cell motilityGO:20001471770.096
metal ion homeostasisGO:00550651690.093
regulation of cell cycleGO:00517263930.092
positive regulation of transportGO:00510503360.091
negative regulation of cytokine production involved in immune responseGO:0002719130.091
regulation of cell migrationGO:00303342890.090
single organismal cell cell adhesionGO:00163371480.090
cytokine secretionGO:0050663640.089
cytokine mediated signaling pathwayGO:00192211090.089
Human
positive regulation of protein transportGO:00512221350.089
cellular cation homeostasisGO:00300031630.088
positive regulation of leukocyte activationGO:0002696800.088
Human
nitrogen compound transportGO:00717051910.087
regulation of protein kinase activityGO:00458592890.086
erk1 and erk2 cascadeGO:00703711040.086
positive regulation of t cell activationGO:0050870540.085
negative regulation of interferon beta productionGO:003268840.085
cellular ion homeostasisGO:00068731680.085
tumor necrosis factor superfamily cytokine productionGO:0071706450.085
Human
regulation of transferase activityGO:00513383550.085
Human
regulation of calcium ion transportGO:0051924790.083
interferon beta productionGO:0032608230.083
activation of immune responseGO:00022531140.082
Human
hemopoiesisGO:00300971800.082
regulation of cell motilityGO:20001452990.081
divalent inorganic cation transportGO:00725111580.080
cellular response to lipidGO:00713961270.079
positive regulation of locomotionGO:00400171860.079
response to virusGO:00096151260.079
Human Mouse
negative regulation of secretionGO:0051048580.079
purine ribonucleotide catabolic processGO:00091544040.079
immune response regulating cell surface receptor signaling pathwayGO:0002768510.078
positive regulation of cellular amino acid metabolic processGO:004576430.078
response to lipopolysaccharideGO:0032496700.078
taxisGO:00423301570.077
negative regulation of secretion by cellGO:1903531520.077
cation homeostasisGO:00550801890.077
regulation of vesicle mediated transportGO:00606271300.077
calcium ion homeostasisGO:00550741220.077
adaptive immune responseGO:0002250490.076
regulation of dendritic cell apoptotic processGO:200066840.075
amine metabolic processGO:0009308440.074
organophosphate catabolic processGO:00464344300.072
regulation of tumor necrosis factor productionGO:0032680430.070
Human
inflammatory responseGO:0006954790.069
cytokine production involved in immune responseGO:0002367270.069
Human
positive regulation of leukocyte migrationGO:0002687460.069
regulation of cellular ketone metabolic processGO:0010565500.069
regulation of gamma delta t cell activation involved in immune responseGO:200119110.069
lymphocyte mediated immunityGO:0002449480.067
negative regulation of dendritic cell apoptotic processGO:200066930.067
myeloid leukocyte migrationGO:0097529620.067
regulation of interferon gamma productionGO:0032649360.067
regulation of response to biotic stimulusGO:0002831550.066
cytoplasmic transportGO:00164823790.066
regulation of protein serine threonine kinase activityGO:00719001790.065
positive regulation of nucleotide metabolic processGO:00459812300.065
ribonucleoside triphosphate metabolic processGO:00091994120.065
positive regulation of cell differentiationGO:00455972110.065
negative regulation of interleukin 12 secretionGO:200118310.065
purine containing compound catabolic processGO:00725234110.065
purine ribonucleoside catabolic processGO:00461303980.065
regulation of lymphocyte activationGO:00512491030.064
Human
cellular ketone metabolic processGO:0042180800.064
fc receptor mediated inhibitory signaling pathwayGO:000277420.064
negative regulation of tumor necrosis factor biosynthetic processGO:004253630.064
regulation of cellular component movementGO:00512703340.063
chemical homeostasisGO:00488783060.063
positive regulation of cytosolic calcium ion concentrationGO:0007204820.063
cell activation involved in immune responseGO:0002263300.063
cellular chemical homeostasisGO:00550821800.063
negative regulation of apoptotic processGO:00430663160.062
ribonucleoside catabolic processGO:00424544060.061
regulation of i kappab kinase nf kappab signalingGO:00431221620.061
interferon gamma productionGO:0032609390.061
purine ribonucleoside metabolic processGO:00461284370.060
regulation of cell differentiationGO:00455953930.060
purine ribonucleoside triphosphate metabolic processGO:00092054110.060
ribonucleotide catabolic processGO:00092614050.059
complement receptor mediated signaling pathwayGO:000243030.059
serotonin transportGO:000683730.059
purine nucleoside triphosphate catabolic processGO:00091463920.059
extrinsic apoptotic signaling pathwayGO:00971911190.058
regulation of sequence specific dna binding transcription factor activityGO:00510902110.058
regulation of nucleoside metabolic processGO:00091182090.058
negative regulation of serotonin secretionGO:001406310.057
interleukin 8 productionGO:0032637510.057
Human
positive regulation of transferase activityGO:00513472270.057
positive regulation of cellular amine metabolic processGO:003324070.056
cell chemotaxisGO:00603261120.056
negative regulation of immune system processGO:00026831360.056
Human
second messenger mediated signalingGO:0019932780.056
immune system developmentGO:00025201950.056
positive regulation of innate immune responseGO:0045089790.055
Human
i kappab kinase nf kappab signalingGO:00072491660.055
positive regulation of response to external stimulusGO:0032103880.055
type i interferon productionGO:0032606270.054
positive regulation of cell migrationGO:00303351720.054
negative regulation of cellular protein metabolic processGO:00322693530.054
Human
myeloid cell differentiationGO:00300991170.054
endocytosisGO:00068971590.053
ribonucleoside triphosphate catabolic processGO:00092033910.053
regulation of leukocyte differentiationGO:1902105610.053
nucleoside catabolic processGO:00091644080.052
cytokine biosynthetic processGO:0042089370.052
Human
positive regulation of cellular component organizationGO:00511303760.052
negative regulation of ion transportGO:0043271390.052
positive regulation of kinase activityGO:00336742040.052
regulation of adaptive immune responseGO:0002819330.051
positive regulation of protein kinase activityGO:00458601900.051
regulation of small gtpase mediated signal transductionGO:00510561560.051
nucleotide catabolic processGO:00091664080.051
regulation of purine nucleotide metabolic processGO:19005422640.051
gtp catabolic processGO:00061842370.051
leukocyte mediated immunityGO:0002443590.050
hematopoietic or lymphoid organ developmentGO:00485341860.050
positive regulation of organelle organizationGO:00106381950.050
ion homeostasisGO:00508012300.050
cellular homeostasisGO:00197251960.050
regulation of nucleotide catabolic processGO:00308112050.049
positive regulation of cellular component movementGO:00512721810.049
regulation of chemotaxisGO:0050920740.048
positive regulation of secretion by cellGO:19035321080.048
negative regulation of programmed cell deathGO:00430693210.048
regulation of gtpase activityGO:00430871800.048
regulation of myeloid leukocyte differentiationGO:0002761390.048
response to cytokineGO:00340972320.048
Human
purine ribonucleoside triphosphate catabolic processGO:00092073910.047
regulation of type i interferon productionGO:0032479260.047
guanosine containing compound catabolic processGO:19010692390.047
enzyme linked receptor protein signaling pathwayGO:00071673030.046
positive regulation of mapk cascadeGO:00434101900.046
Human
positive regulation of developmental processGO:00510943140.046
activation of innate immune responseGO:0002218550.045
Human
positive regulation of catabolic processGO:00098963100.045
negative regulation of catalytic activityGO:00430863350.045
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.045
Human
regulation of ras protein signal transductionGO:00465781550.045
nucleoside triphosphate metabolic processGO:00091414220.045
post embryonic developmentGO:000979120.045
regulation of proteolysisGO:00301622930.044
serotonin secretionGO:000182010.044
glycosyl compound catabolic processGO:19016584130.044
dendritic cell differentiationGO:0097028130.044
regulation of behaviorGO:0050795820.044
response to abiotic stimulusGO:00096283360.044
nucleoside triphosphate catabolic processGO:00091433940.044
regulation of defense response to virus by hostGO:0050691220.044
purine nucleoside triphosphate metabolic processGO:00091444120.043
response to nitrogen compoundGO:19016981840.043
Human
negative regulation of leukocyte activationGO:0002695260.043
positive regulation of chemotaxisGO:0050921570.043
purine nucleoside catabolic processGO:00061523980.043
nervous system developmentGO:00073992930.042
negative regulation of immune responseGO:0050777400.042
Human
cell developmentGO:00484683280.042
regulation of nucleotide metabolic processGO:00061402690.042
negative regulation of cellular component organizationGO:00511292350.041
antigen processing and presentationGO:0019882330.041
immune response activating signal transductionGO:0002757900.041
Human
organic hydroxy compound transportGO:0015850630.041
system processGO:00030083490.041
Human
female gamete generationGO:000729220.040
dendritic cell apoptotic processGO:009704840.040
protein localization to organelleGO:00333652800.040
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.040
cellular protein complex assemblyGO:00436231880.040
Mouse
negative regulation of intracellular signal transductionGO:19025321830.040
regulation of kinase activityGO:00435493140.040
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.040
cell killingGO:0001906340.040
neurological system processGO:00508771630.040
cellular divalent inorganic cation homeostasisGO:00725031280.039
memoryGO:000761330.039
type i interferon secretionGO:007264110.039
t cell proliferationGO:0042098450.039
regulation of cytokine production involved in immune responseGO:0002718220.039
cytokine metabolic processGO:0042107380.039
Human
response to molecule of bacterial originGO:0002237820.039
apoptotic signaling pathwayGO:00971902680.038
regulation of osteoclast differentiationGO:0045670180.038
negative regulation of production of molecular mediator of immune responseGO:0002701130.038
regulation of gtp catabolic processGO:00331241800.038
regulation of regulatory t cell differentiationGO:004558940.038
chemotaxisGO:00069351570.038
positive regulation of leukocyte differentiationGO:1902107370.038
positive regulation of cytokine secretionGO:0050715420.038
interferon beta secretionGO:003554610.038
positive regulation of gtp catabolic processGO:00331261660.037
cytosolic calcium ion homeostasisGO:0051480890.037
response to woundingGO:00096111680.037
regulation of apoptotic signaling pathwayGO:20012331750.037
regulation of interleukin 8 productionGO:0032677490.037
Human
positive regulation of nf kappab transcription factor activityGO:0051092810.037
negative regulation of transportGO:00510511760.037
carbohydrate derivative biosynthetic processGO:19011372070.037
regulation of stress activated mapk cascadeGO:0032872840.037
Human
negative regulation of cell differentiationGO:00455961710.037
natural killer cell mediated immunityGO:0002228230.036
positive regulation of regulatory t cell differentiationGO:004559130.036
negative regulation of cell cycleGO:00457861930.036
negative regulation of interferon gamma biosynthetic processGO:004507710.036
innate immune response activating signal transductionGO:0002758480.036
Human
positive regulation of lymphocyte migrationGO:2000403160.036
positive regulation of cytolysisGO:004591930.036
divalent inorganic cation homeostasisGO:00725071360.035
positive regulation of t cell tolerance inductionGO:000266620.035
regulation of lymphocyte mediated immunityGO:0002706330.035
regulation of ras gtpase activityGO:00323181280.035
positive regulation of defense response to virus by hostGO:0002230140.035
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.035
guanosine containing compound metabolic processGO:19010682440.035
cellular response to organic cyclic compoundGO:00714071270.035
cellular metal ion homeostasisGO:00068751460.035
cellular response to endogenous stimulusGO:00714953360.035
Human
negative regulation of leukocyte mediated immunityGO:0002704140.034
leukocyte chemotaxisGO:0030595760.034
negative regulation of transferase activityGO:00513481240.034
cellular calcium ion homeostasisGO:00068741170.034
positive regulation of intracellular transportGO:00323881040.034
Human
positive regulation of cytoplasmic transportGO:1903651820.034
Human
regulation of chemokine productionGO:0032642310.034
regulation of actin filament based processGO:00329701410.033
reactive oxygen species biosynthetic processGO:190340940.033
negative regulation of phosphorus metabolic processGO:00105632670.033
Human
regulation of leukocyte mediated immunityGO:0002703380.033
regulation of cytokine biosynthetic processGO:0042035350.033
Human
positive regulation of defense responseGO:0031349870.033
Human
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.033
Human
positive regulation of immune effector processGO:0002699400.033
positive regulation of stress activated mapk cascadeGO:0032874600.033
Human
lipid metabolic processGO:00066293810.033
regulation of gamma delta t cell activationGO:004664310.033
detection of stimulusGO:0051606850.033
Human
regulation of peptidase activityGO:00525471800.033
actin cytoskeleton organizationGO:00300362070.033
gtp metabolic processGO:00460392390.033
regulation of cellular response to stressGO:00801352440.033
Human
regulation of intracellular transportGO:00323861950.033
regulation of cellular component biogenesisGO:00440872810.033
calcium mediated signalingGO:0019722440.033
regulation of inflammatory responseGO:0050727460.033
regulation of lymphocyte migrationGO:2000401220.032
regulation of defense response to virusGO:0050688330.032
nucleoside phosphate catabolic processGO:19012924120.032
regulation of cytoskeleton organizationGO:00514931770.032
negative regulation of immune effector processGO:0002698380.032
positive regulation of cellular catabolic processGO:00313312840.032
regulation of transforming growth factor beta secretionGO:200120110.032
transmembrane transportGO:00550853990.032
negative regulation of protein modification processGO:00314002000.032
Human
negative regulation of leukocyte differentiationGO:1902106240.032
cation transmembrane transportGO:00986552380.032
single organism cellular localizationGO:19025803320.032
negative regulation of phosphate metabolic processGO:00459362670.032
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.031
oogenesisGO:004847720.031
positive regulation of macrophage chemotaxisGO:001075930.031
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.031
positive regulation of jnk cascadeGO:0046330520.031
Human
maintenance of locationGO:00512351120.031
Human
positive regulation of ion transportGO:0043270870.031
response to growth factorGO:00708482050.031
cellular macromolecular complex assemblyGO:00346223240.031
Mouse
negative regulation of interleukin 10 productionGO:003269370.031
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cellGO:000229140.031
regulation of endocytosisGO:0030100720.030
regulation of cell adhesionGO:00301551660.030
regulation of camp metabolic processGO:0030814520.030
negative regulation of transforming growth factor beta secretionGO:200120210.030
defense response to bacteriumGO:0042742630.030
Human
intracellular protein transportGO:00068862700.030
positive regulation of secretionGO:00510471160.030
amide transportGO:0042886760.030
cellular lipid metabolic processGO:00442553030.029
positive regulation of acute inflammatory responseGO:000267520.029
regulation of interferon beta secretionGO:003554710.029
regulation of natural killer cell mediated cytotoxicityGO:0042269160.029
cellular response to cytokine stimulusGO:00713451810.029
Human
positive regulation of nucleotide catabolic processGO:00308131850.029
regulation of cell cycle processGO:00105642660.029
negative regulation of developmental processGO:00510932470.029
negative regulation of osteoclast developmentGO:200120510.029
regulation of cytoplasmic transportGO:19036491490.029
regulation of response to woundingGO:19030341010.029
neuromuscular junction developmentGO:000752830.029
negative regulation of dendritic cell differentiationGO:200119920.029
sensory perception of painGO:001923340.028
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.028
regulation of calcium ion transport into cytosolGO:0010522330.028
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.028
myeloid leukocyte differentiationGO:0002573600.028
tumor necrosis factor productionGO:0032640430.028
Human
positive regulation of proteolysisGO:00458621420.028
regulation of system processGO:00440571010.028
pattern recognition receptor signaling pathwayGO:0002221480.028
Human
ion transmembrane transportGO:00342203380.028
protein processingGO:00164852260.028
Mouse
transforming growth factor beta secretionGO:003804410.028
nucleocytoplasmic transportGO:00069131760.028
leukocyte mediated cytotoxicityGO:0001909270.028
regulation of cytokine mediated signaling pathwayGO:0001959410.028
Human
positive regulation of behaviorGO:0048520600.027
heterotypic cell cell adhesionGO:0034113280.027
leukocyte differentiationGO:0002521980.027
osteoclast developmentGO:003603520.027
positive regulation of cell adhesionGO:0045785840.027
cell morphogenesisGO:00009022960.027
regulation of purine nucleotide catabolic processGO:00331212050.027
regulation of osteoclast developmentGO:200120410.027
cellular response to growth factor stimulusGO:00713631970.027
actin filament organizationGO:00070151280.027
activation of protein kinase activityGO:0032147900.026
eosinophil activation involved in immune responseGO:000227820.026
reactive nitrogen species metabolic processGO:200105730.026
leukocyte apoptotic processGO:0071887310.026
regulation of actin filament polymerizationGO:0030833500.026
cellular response to dna damage stimulusGO:00069743790.026
protein catabolic processGO:00301633250.026
regulation of rho protein signal transductionGO:0035023790.025
determination of adult lifespanGO:000834020.025
jnk cascadeGO:0007254800.025
Human
granulocyte migrationGO:0097530400.025
regulation of reactive oxygen species metabolic processGO:2000377410.025
multicellular organismal agingGO:001025930.025
t cell tolerance inductionGO:000251740.025
interleukin 10 productionGO:0032613170.025
negative regulation of protein transportGO:0051224750.025
locomotory behaviorGO:000762610.025
regulation of map kinase activityGO:00434051080.025
interleukin 10 secretionGO:007260850.025
immune response activating cell surface receptor signaling pathwayGO:0002429450.025
peptidyl tyrosine phosphorylationGO:00181081700.025
gamma delta t cell activation involved in immune responseGO:000229010.025
chemokine productionGO:0032602320.025
regulation of peptidyl tyrosine phosphorylationGO:00507301080.025
peptide transportGO:0015833740.025
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.024
Mouse
regulation of cysteine type endopeptidase activityGO:20001161270.024
response to organonitrogen compoundGO:00102431560.024
Human
generation of neuronsGO:00486991520.024
cell projection organizationGO:00300302520.024
myeloid leukocyte activationGO:0002274340.024
organonitrogen compound biosynthetic processGO:19015662000.024
lymphocyte migrationGO:0072676280.024
regulation of cell killingGO:0031341220.024
negative regulation of calcium ion transportGO:0051926190.024
stress activated mapk cascadeGO:0051403930.024
Human
negative regulation of t cell mediated cytotoxicityGO:000191510.024
regulation of dendritic cell differentiationGO:200119830.024
dephosphorylationGO:00163112090.024
regulation of myeloid cell differentiationGO:0045637810.024
regulation of epithelial cell proliferationGO:00506781130.024
regulation of reactive oxygen species biosynthetic processGO:190342630.024
sequestering of metal ionGO:0051238240.023
sequestering of calcium ionGO:0051208170.023
response to hormoneGO:00097251750.023
behaviorGO:00076101120.023
neurogenesisGO:00220081690.023
reactive oxygen species metabolic processGO:0072593750.023
positive regulation of t cell migrationGO:2000406130.023
negative regulation of interleukin 10 secretionGO:200118010.023
positive regulation of cytoskeleton organizationGO:0051495830.023
regulation of homeostatic processGO:00328441210.023
positive regulation of apoptotic signaling pathwayGO:2001235700.023
negative regulation of kinase activityGO:00336731060.023
positive regulation of interferon gamma productionGO:0032729260.023
t cell mediated immunityGO:0002456250.023
intrinsic apoptotic signaling pathwayGO:00971931270.023
eosinophil degranulationGO:004330820.023
negative regulation of defense responseGO:0031348470.023
response to interleukin 1GO:0070555470.023
granulocyte chemotaxisGO:0071621370.023
positive regulation of gamma delta t cell activationGO:004664510.023
mitotic cell cycleGO:00002783260.023
lipopolysaccharide mediated signaling pathwayGO:0031663260.023
regulation of natural killer cell mediated immunityGO:0002715160.023
cellular response to nitrogen compoundGO:19016991440.023
Human
interleukin 12 productionGO:0032615150.023
regulation of cell developmentGO:00602841610.023
purine nucleotide catabolic processGO:00061954050.022
positive regulation of gtpase activityGO:00435471660.022
positive regulation of protein import into nucleusGO:0042307460.022
Human
regulation of interleukin 12 secretionGO:200118210.022
gamma delta t cell activationGO:004662930.022

NLRP3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.067
Human
disease of cellular proliferationDOID:145661740.067
Human
organ system cancerDOID:00506861640.041