Homo sapiens

110 known processes

PSEN1

presenilin 1

(Aliases: PS-1,PS1,S182,AD3,FAD)

PSEN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cardiac muscle cell cardiac muscle cell adhesionGO:008604211.000
cardiac muscle cell action potential involved in contractionGO:0086002210.999
desmosome assemblyGO:000215940.998
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.996
Mouse
negative regulation of catagenGO:005179610.993
cardiac muscle cell action potentialGO:0086001230.989
thymus developmentGO:004853830.988
Mouse
associative learningGO:000830610.986
catagenGO:004263730.985
single organismal cell cell adhesionGO:00163371480.983
cell adhesionGO:00071553250.981
system processGO:00030083490.981
Mouse
muscle contractionGO:0006936730.980
action potentialGO:0001508340.975
negative regulation of canonical wnt signaling pathwayGO:0090090550.973
low density lipoprotein particle mediated signalingGO:005509610.971
cardiac muscle cell contractionGO:008600340.971
positive regulation of keratinocyte proliferationGO:001083840.971
regulation of membrane potentialGO:0042391950.970
Mouse
regulation of canonical wnt signaling pathwayGO:0060828880.953
cell activationGO:00017752130.953
Mouse
neurological system processGO:00508771630.952
Mouse
cell cell signalingGO:00072671550.948
Mouse Fly
somitogenesisGO:000175620.942
Mouse
membrane protein proteolysisGO:0033619380.939
biological adhesionGO:00226103310.937
regulation of apoptotic signaling pathwayGO:20012331750.935
Mouse
cell migration involved in gastrulationGO:004207410.935
motor neuron axon guidanceGO:000804520.933
multicellular organismal signalingGO:0035637340.932
blood circulationGO:00080151130.932
canonical wnt signaling pathwayGO:00600701160.931
Zebrafish
embryonic morphogenesisGO:0048598850.930
Mouse
t cell activationGO:0042110990.928
Mouse
neural tube developmentGO:002191590.925
Mouse
skin developmentGO:0043588760.923
Mouse
endomembrane system organizationGO:00102561960.915
regulation of protein bindingGO:0043393660.911
Mouse
positive regulation of transportGO:00510503360.906
negative regulation of apoptotic signaling pathwayGO:2001234970.904
Mouse
negative regulation of protein processingGO:00109551420.901
Mouse
regulation of peptidase activityGO:00525471800.900
regulation of cardiac muscle cell contractionGO:0086004230.900
regulation of cell differentiationGO:00455953930.897
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.895
cellular chemical homeostasisGO:00550821800.891
memoryGO:000761330.886
Mouse
protein maturationGO:00516042330.886
positive regulation of intracellular protein transportGO:0090316760.881
regulation of protein localizationGO:00328802960.881
beta amyloid metabolic processGO:0050435120.880
Zebrafish Mouse
protein localization to membraneGO:00726571600.872
positive regulation of apoptotic signaling pathwayGO:2001235700.871
ubiquitin dependent protein catabolic processGO:00065112060.869
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.859
Mouse
ventricular cardiac muscle cell action potentialGO:0086005150.856
g protein coupled receptor signaling pathwayGO:00071862070.852
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.849
hematopoietic or lymphoid organ developmentGO:00485341860.844
Mouse
intermediate filament based processGO:0045103170.844
single organism cell adhesionGO:00986021790.842
negative regulation of developmental processGO:00510932470.840
Mouse
negative regulation of wnt signaling pathwayGO:0030178690.839
regulation of melanosome transportGO:190290810.836
wnt signaling pathwayGO:00160551560.834
Zebrafish
canonical wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transitionGO:004433420.834
hair cycleGO:0042633280.823
Mouse
protein processingGO:00164852260.814
response to oxygen containing compoundGO:19017003690.813
cellular divalent inorganic cation homeostasisGO:00725031280.809
regulation of protein maturationGO:19033171500.806
Mouse
regulation of proteolysisGO:00301622930.805
Mouse
keratinocyte differentiationGO:0030216360.804
cardiac muscle contractionGO:0060048340.798
positive regulation of catabolic processGO:00098963100.797
Mouse
visual learningGO:000854210.791
negative regulation of proteolysisGO:00458611320.790
Mouse
regulation of synaptic plasticityGO:004816730.786
Mouse
regulation of cardiac muscle contractionGO:0055117330.785
plasma membrane organizationGO:00070091150.784
epithelium developmentGO:00604292270.768
Zebrafish Mouse
single organism cellular localizationGO:19025803320.766
cell communication involved in cardiac conductionGO:0086065180.762
heart contractionGO:0060047620.760
negative regulation of protein maturationGO:19033181420.759
Mouse
regulation of melanin biosynthetic processGO:004802110.756
regulation of cell cycleGO:00517263930.752
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.751
regulation of wnt signaling pathwayGO:00301111230.747
positive regulation of protein import into nucleusGO:0042307460.747
cellular homeostasisGO:00197251960.746
behaviorGO:00076101120.744
Zebrafish Mouse
branching involved in salivary gland morphogenesisGO:006044510.743
regulation of endopeptidase activityGO:00525481700.740
brain morphogenesisGO:004885410.739
Mouse
actin mediated cell contractionGO:0070252120.739
lymphocyte activationGO:00466491330.739
Mouse
positive regulation of hydrolase activityGO:00513453310.736
negative regulation of ubiquitin protein transferase activityGO:005144480.735
Mouse
actin filament based movementGO:0030048170.719
rho protein signal transductionGO:0007266260.715
heart processGO:0003015620.715
positive regulation of programmed cell deathGO:00430682490.714
Mouse
protein localization to adherens junctionGO:007189620.713
positive regulation of nucleotide metabolic processGO:00459812300.713
receptor metabolic processGO:0043112810.713
Mouse
cardiovascular system developmentGO:00723582620.712
Zebrafish Mouse
regulation of heart rateGO:0002027380.708
salivary gland morphogenesisGO:000743540.703
regulation of protein ubiquitinationGO:0031396950.693
Mouse
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.686
protein localization to plasma membraneGO:0072659930.685
membrane protein ectodomain proteolysisGO:0006509330.675
positive regulation of cell deathGO:00109422630.672
Mouse
embryonic appendage morphogenesisGO:003511390.667
Mouse
embryo developmentGO:00097901230.665
Zebrafish Mouse
positive regulation of secretion by cellGO:19035321080.664
striated muscle contractionGO:0006941520.661
cardiac muscle tissue developmentGO:0048738390.661
positive regulation of secretionGO:00510471160.660
notch receptor processingGO:000722020.656
Mouse Fly
cellular amide metabolic processGO:0043603690.656
Zebrafish Mouse
leukocyte differentiationGO:0002521980.655
Mouse
regulation of protein catabolic processGO:00421761550.654
Mouse
epithelial cell proliferationGO:00506731280.647
Mouse
smooth muscle cell proliferationGO:0048659280.645
regulation of protein transportGO:00512232130.643
cytokine productionGO:00018162470.642
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.641
cell cell adhesion involved in gastrulationGO:007058660.640
regulation of cellular amino acid metabolic processGO:000652160.638
cellular ion homeostasisGO:00068731680.633
metal ion homeostasisGO:00550651690.625
cellular cation homeostasisGO:00300031630.623
modification dependent protein catabolic processGO:00199412090.622
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.621
regulation of body fluid levelsGO:0050878990.611
regulation of immune responseGO:00507762010.605
Mouse
epidermis developmentGO:0008544590.587
Mouse
hair cycle processGO:0022405120.585
Mouse
positive regulation of proteolysisGO:00458621420.576
Mouse
protein catabolic processGO:00301633250.574
Mouse
negative regulation of interleukin 4 productionGO:003271330.567
vasculature developmentGO:00019441810.566
Zebrafish Mouse
regulation of establishment of protein localizationGO:00702012420.565
negative regulation of protein metabolic processGO:00512483910.561
Mouse
i kappab kinase nf kappab signalingGO:00072491660.559
regulation of protein modification by small protein conjugation or removalGO:19033201070.557
Mouse
intermediate filament cytoskeleton organizationGO:0045104170.556
positive regulation of cell cycleGO:00457871400.555
small gtpase mediated signal transductionGO:0007264780.551
negative regulation of apoptotic processGO:00430663160.547
cell cell junction organizationGO:0045216690.545
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.541
Mouse
positive regulation of cellular catabolic processGO:00313312840.539
Mouse
endocrine system developmentGO:0035270260.538
nucleoside triphosphate catabolic processGO:00091433940.536
cilium organizationGO:0044782680.535
positive regulation of protein transportGO:00512221350.533
regulation of purine nucleotide catabolic processGO:00331212050.528
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.526
lymphocyte proliferationGO:0046651700.524
ion homeostasisGO:00508012300.523
pituitary gland developmentGO:002198320.523
positive regulation of intracellular transportGO:00323881040.521
inorganic cation transmembrane transportGO:00986621940.520
antigen receptor mediated signaling pathwayGO:0050851380.520
Mouse
cellular calcium ion homeostasisGO:00068741170.515
establishment or maintenance of bipolar cell polarityGO:006124520.513
immune system developmentGO:00025201950.513
Mouse
intermediate filament organizationGO:0045109100.510
gland developmentGO:0048732480.505
Mouse
cell developmentGO:00484683280.502
Mouse Fly
modification dependent macromolecule catabolic processGO:00436322120.502
Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.495
leukocyte proliferationGO:0070661740.494
segmentationGO:003528240.489
Mouse
regulation of heart rate by cardiac conductionGO:0086091190.488
molting cycle processGO:0022404120.488
Mouse
protein ubiquitinationGO:00165673140.482
Mouse
negative regulation of cell fate specificationGO:000999630.481
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.481
protein localization to organelleGO:00333652800.476
negative regulation of protein modification processGO:00314002000.476
Mouse
purine nucleoside triphosphate catabolic processGO:00091463920.469
coagulationGO:0050817780.468
Mouse
circulatory system processGO:00030131130.467
regulation of cell cycle processGO:00105642660.465
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.463
Mouse
cation homeostasisGO:00550801890.462
protein importGO:00170381300.462
positive regulation of nucleoside metabolic processGO:00459791860.461
regulation of monophenol monooxygenase activityGO:003277110.459
keratinizationGO:003142420.459
positive regulation of epithelial cell proliferationGO:0050679650.457
regulation of heart contractionGO:0008016500.455
regulation of erbb signaling pathwayGO:1901184270.452
Mouse
neural tube formationGO:000184130.450
nucleoside catabolic processGO:00091644080.448
purine ribonucleotide catabolic processGO:00091544040.444
uterus morphogenesisGO:006103820.432
regulation of proteasomal protein catabolic processGO:0061136870.431
Mouse
negative regulation of interleukin 5 productionGO:003271430.430
protein stabilizationGO:0050821640.430
membrane organizationGO:00610242920.428
purine containing compound catabolic processGO:00725234110.426
cytoplasmic transportGO:00164823790.420
single organism membrane organizationGO:00448022680.419
positive regulation of immune system processGO:00026842830.418
Mouse
positive regulation of transcription factor import into nucleusGO:0042993250.418
protein homooligomerizationGO:00512601000.416
positive regulation of cellular component organizationGO:00511303760.416
apoptotic signaling pathwayGO:00971902680.414
Mouse
forebrain developmentGO:0030900260.413
Mouse
regulation of ligase activityGO:0051340290.413
Mouse
neuronal action potentialGO:001922890.411
hair follicle maturationGO:004882030.410
Mouse
appendage morphogenesisGO:0035107160.408
Mouse
protein import into nucleusGO:00066061040.403
actin filament based processGO:00300292240.400
collateral sproutingGO:004866820.400
positive regulation of proteoglycan biosynthetic processGO:190273030.398
t cell proliferationGO:0042098450.396
regulation of carbohydrate metabolic processGO:0006109540.395
hair cycle phaseGO:004485130.392
Mouse
extrinsic apoptotic signaling pathwayGO:00971911190.391
positive regulation of cytoplasmic transportGO:1903651820.389
brain developmentGO:0007420970.388
Zebrafish Mouse
anion transportGO:00068201610.384
Mouse
glycoprotein biosynthetic processGO:0009101910.383
Mouse
intracellular protein transportGO:00068862700.383
negative regulation of type b pancreatic cell apoptotic processGO:200067530.382
negative regulation of peptidase activityGO:0010466910.382
positive regulation of immune responseGO:00507781590.381
Mouse
cellular glucan metabolic processGO:0006073220.379
glycosyl compound catabolic processGO:19016584130.377
regulation of rho protein signal transductionGO:0035023790.377
regulation of cellular component biogenesisGO:00440872810.376
cell cycle arrestGO:0007050710.376
pharynx developmentGO:006046510.376
odontogenesisGO:0042476250.373
protein modification by small protein conjugationGO:00324463420.369
Mouse
purine nucleoside triphosphate metabolic processGO:00091444120.369
single organism nuclear importGO:19025931040.368
dorsal ventral pattern formationGO:0009953150.367
Mouse Fly
regulation of cytokine productionGO:00018172320.362
neuron differentiationGO:00301821380.362
Mouse Fly
actin crosslink formationGO:005176410.361
positive regulation of cell proliferation in bone marrowGO:007186410.359
proteasomal protein catabolic processGO:00104981760.358
Mouse
secondary metabolite biosynthetic processGO:004455020.357
positive regulation of nucleocytoplasmic transportGO:0046824540.350
positive regulation of protein catabolic processGO:0045732750.348
Mouse
chordate embryonic developmentGO:0043009340.348
Mouse
columnar cuboidal epithelial cell differentiationGO:0002065140.342
Zebrafish
positive regulation of organelle organizationGO:00106381950.341
positive regulation of proteasomal protein catabolic processGO:1901800350.338
Mouse
negative regulation of multicellular organismal processGO:00512413170.335
Mouse
secretionGO:00469032540.334
Mouse
developmental maturationGO:0021700280.332
Mouse
positive regulation of apoptotic processGO:00430652460.331
Mouse
sensory perceptionGO:00076001030.328
nervous system developmentGO:00073992930.323
Zebrafish Mouse Fly
ectoderm developmentGO:000739830.320
regulation of muscle system processGO:0090257530.320
regulation of neurogenesisGO:0050767820.320
Mouse
dopamine receptor signaling pathwayGO:0007212100.319
organ morphogenesisGO:00098871470.316
Mouse
cellular ketone metabolic processGO:0042180800.313
cell junction assemblyGO:0034329670.312
gtp catabolic processGO:00061842370.311
immune response activating signal transductionGO:0002757900.311
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.311
negative regulation of catalytic activityGO:00430863350.309
Mouse
regulation of purine nucleotide metabolic processGO:19005422640.309
immune response regulating signaling pathwayGO:0002764970.308
Mouse
establishment of protein localization to membraneGO:00901501210.308
maintenance of location in cellGO:0051651620.304
behavioral response to ethanolGO:004814920.301
cation transportGO:00068123310.300
neuroblast proliferationGO:000740540.298
positive regulation of purine nucleotide catabolic processGO:00331231850.298
muscle system processGO:0003012810.298
female gamete generationGO:000729220.296
regulation of cytoskeleton organizationGO:00514931770.296
regulation of receptor recyclingGO:0001919100.295
Mouse
cerebral cortex cell migrationGO:002179530.294
Mouse
organophosphate catabolic processGO:00464344300.292
gastrulationGO:0007369510.292
amyloid precursor protein metabolic processGO:0042982170.288
Zebrafish Mouse
negative regulation of cellular protein metabolic processGO:00322693530.287
Mouse
regulation of blood circulationGO:1903522590.286
regulation of protein import into nucleusGO:0042306780.286
regulation of interleukin 5 productionGO:003267460.283
receptor recyclingGO:0001881150.282
Mouse
protein oligomerizationGO:00512591730.279
negative regulation of hair follicle developmentGO:005179910.278
regulation of intracellular transportGO:00323861950.277
negative regulation of hair follicle maturationGO:004881710.275
regulation of cysteine type endopeptidase activityGO:20001161270.275
peptide metabolic processGO:0006518510.271
Zebrafish Mouse
regulation of i kappab kinase nf kappab signalingGO:00431221620.270
protein targeting to nucleusGO:00447441040.270
bundle of his cell to purkinje myocyte communicationGO:008606980.267
response to cytokineGO:00340972320.266
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.265
positive regulation of mesenchymal cell proliferationGO:000205320.264
adult locomotory behaviorGO:000834410.264
regulation of protein processingGO:00706131500.263
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.259
Mouse
posttranscriptional regulation of gene expressionGO:00106082130.258
negative regulation of endopeptidase activityGO:0010951840.257
protein localization to cell surfaceGO:0034394280.247
muscle tissue developmentGO:0060537620.246
post embryonic organ developmentGO:004856910.245
regulation of nucleocytoplasmic transportGO:0046822980.244
purine ribonucleoside triphosphate metabolic processGO:00092054110.243
cellular metal ion homeostasisGO:00068751460.242
embryo development ending in birth or egg hatchingGO:0009792340.242
Mouse
ribonucleotide catabolic processGO:00092614050.241
negative regulation of epidermal growth factor activated receptor activityGO:000717560.238
Mouse
regulation of cell motilityGO:20001452990.237
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.237
positive regulation of developmental processGO:00510943140.237
cilium assemblyGO:0042384630.237
amyloid precursor protein catabolic processGO:0042987120.236
Zebrafish Mouse
biological phaseGO:004484850.236
Mouse
myeloid leukocyte differentiationGO:0002573600.236
Mouse
symbiosis encompassing mutualism through parasitismGO:00444031560.236
regulation of cytoplasmic transportGO:19036491490.235
multicellular organismal agingGO:001025930.235
positive regulation of secondary metabolite biosynthetic processGO:190037810.234
leukocyte activationGO:00453211640.234
Mouse
regulation of nucleoside metabolic processGO:00091182090.234
tube developmentGO:00352951250.233
Mouse
regulation of cellular protein catabolic processGO:1903362960.233
Mouse
nucleoside triphosphate metabolic processGO:00091414220.233
pigmentationGO:0043473220.232
Zebrafish
specification of organ identityGO:001009230.232
ribonucleoside catabolic processGO:00424544060.231
regulation of actin filament based movementGO:1903115240.229
lung alveolus developmentGO:004828640.228
muscle tissue morphogenesisGO:0060415190.224
regulation of system processGO:00440571010.222
purine nucleoside catabolic processGO:00061523980.221
circulatory system developmentGO:00723592620.221
Zebrafish Mouse
muscle cell proliferationGO:0033002350.218
regulation of rho gtpase activityGO:0032319660.215
embryonic epithelial tube formationGO:000183840.210
positive regulation of cell cycle processGO:00900681060.208
cell substrate adhesionGO:00315891320.206
cardiac conductionGO:0061337230.206
canonical wnt signaling pathway involved in heart developmentGO:006131630.205
gastrulation with mouth forming secondGO:000170210.204
negative regulation of peptidyl tyrosine phosphorylationGO:0050732200.202
Mouse
negative regulation of catabolic processGO:00098951040.202
Mouse
sulfur compound metabolic processGO:00067901010.200
purine ribonucleoside catabolic processGO:00461303980.198
transmembrane transportGO:00550853990.198
activation of immune responseGO:00022531140.196
Mouse
positive regulation of cell divisionGO:0051781590.195
regulation of growthGO:00400081650.195
regulation of neuron migrationGO:200122230.193
somite developmentGO:006105370.192
Zebrafish Mouse
cellular amine metabolic processGO:0044106410.192
ion transmembrane transportGO:00342203380.192
embryonic forelimb morphogenesisGO:003511540.191
striated muscle tissue developmentGO:0014706590.190
blood coagulationGO:0007596760.190
cell fate specificationGO:000170880.189
Mouse
digestive tract developmentGO:0048565750.189
purine ribonucleoside metabolic processGO:00461284370.188
epithelial cell differentiationGO:00308551410.187
Zebrafish
regulation of intracellular protein transportGO:00331571230.187
positive regulation of cell motilityGO:20001471770.187
anatomical structure formation involved in morphogenesisGO:00486462840.186
Mouse
adenylate cyclase inhibiting dopamine receptor signaling pathwayGO:000719540.186
nucleoside monophosphate metabolic processGO:00091231910.185
visual behaviorGO:000763220.185
embryonic limb morphogenesisGO:003032690.185
Mouse
negative regulation of protein transportGO:0051224750.184
regulation of protein complex assemblyGO:00432541470.183
cell morphogenesisGO:00009022960.181
Mouse Fly
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103030.181
response to radiationGO:00093141510.180
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.176
Mouse
muscle structure developmentGO:0061061980.175
cellular macromolecule catabolic processGO:00442653800.175
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.175
lipoprotein particle mediated signalingGO:005509510.174
anatomical structure maturationGO:007169590.174
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.174
Mouse
mesenchyme developmentGO:0060485590.174
cognitionGO:0050890430.173
Mouse
negative regulation of hydrolase activityGO:00513461820.173
hemopoiesisGO:00300971800.172
Mouse
nuclear transportGO:00511691790.172
covalent chromatin modificationGO:00165692540.171
oogenesisGO:004847720.171
epidermal cell differentiationGO:0009913450.169
cardiac cell fate specificationGO:006091210.169
regulation of transcription factor import into nucleusGO:0042990390.166
negative regulation of protein bindingGO:0032091350.166
protein targetingGO:00066051870.166
establishment of protein localization to plasma membraneGO:0090002680.164
immune responseGO:00069553070.164
Mouse
positive regulation of melanosome transportGO:190291010.162
mitotic cell cycle processGO:19030472860.161
cellular amino acid metabolic processGO:00065201160.160
regulation of epidermal growth factor activated receptor activityGO:0007176140.159
Mouse
developmental pigmentationGO:0048066120.159
Zebrafish
ventricular cardiac muscle tissue morphogenesisGO:0055010140.159
positive regulation of protein localization to nucleusGO:1900182480.158
peptidyl tyrosine phosphorylationGO:00181081700.158
Mouse
regulation of nucleotide metabolic processGO:00061402690.158
regulation of sulfur metabolic processGO:004276250.157
nucleoside phosphate catabolic processGO:19012924120.155
nucleocytoplasmic transportGO:00069131760.155
regulation of vesicle mediated transportGO:00606271300.155
lung associated mesenchyme developmentGO:006048410.154
regulation of determination of dorsal identityGO:200001520.154
heparan sulfate proteoglycan metabolic processGO:0030201120.154
regulation of glial cell differentiationGO:004568530.154
response to abiotic stimulusGO:00096283360.154
regulation of nucleotide catabolic processGO:00308112050.154
regulation of catagenGO:005179430.153
synaptic vesicle endocytosisGO:004848820.152
epithelial cell morphogenesisGO:000338280.150
regulation of epithelial cell differentiation involved in kidney developmentGO:200069640.149
proteolysis involved in cellular protein catabolic processGO:00516032440.149
Mouse
response to lithium ionGO:001022620.148
negative regulation of gliogenesisGO:001401430.148
regulation of protein targetingGO:1903533910.148
ventricular cardiac muscle tissue developmentGO:0003229140.147
nuclear importGO:00511701060.146
neuron projection developmentGO:00311751060.145
Mouse Fly
limb morphogenesisGO:0035108160.145
Mouse
nephron tubule epithelial cell differentiationGO:007216030.144
negative regulation of neurogenesisGO:0050768260.144
Mouse
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.143
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204330.143
microtubule cytoskeleton organizationGO:00002261760.140
ras protein signal transductionGO:0007265730.139
regulation of muscle contractionGO:0006937450.138
chromatin modificationGO:00165682980.138
mitotic cell cycleGO:00002783260.136
positive regulation of nucleotide catabolic processGO:00308131850.136
purine nucleotide catabolic processGO:00061954050.135
positive regulation of cellular component movementGO:00512721810.134
cellular response to nutrient levelsGO:0031669690.134
Mouse
tube morphogenesisGO:0035239950.134
Mouse
positive regulation of peptidase activityGO:0010952880.134
positive regulation of rho gtpase activityGO:0032321560.133
hair follicle morphogenesisGO:003106920.133
regulation of neuroblast proliferationGO:190269230.132
secretion by cellGO:00329402260.132
Mouse
cilium morphogenesisGO:0060271750.132
regulation of epithelial cell proliferationGO:00506781130.132
negative regulation of transforming growth factor beta2 productionGO:003291220.132
actin cytoskeleton organizationGO:00300362070.132
regulation of multi organism processGO:00439001570.131
regulation of protein stabilityGO:0031647870.131
cytokinesisGO:0000910960.131
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.130
Mouse
cerebral cortex radial glia guided migrationGO:002180110.130
morphogenesis of embryonic epitheliumGO:001633140.130
growthGO:00400072020.130
locomotory behaviorGO:000762610.130
Zebrafish

PSEN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
dementiaDOID:1307191.000
alzheimer s diseaseDOID:10652161.000
central nervous system diseaseDOID:3311861.000
disease of mental healthDOID:150701.000
tauopathyDOID:680161.000
neurodegenerative diseaseDOID:12891021.000
nervous system diseaseDOID:8634311.000
cognitive disorderDOID:1561291.000
heart diseaseDOID:114680.988
cardiovascular system diseaseDOID:12871060.988
musculoskeletal system diseaseDOID:172230.951
muscular diseaseDOID:00800001140.766
bone development diseaseDOID:0080006550.688
bone diseaseDOID:0080001880.688
connective tissue diseaseDOID:651090.688
disease of metabolismDOID:00146672950.648
myopathyDOID:4231040.636
cardiomyopathyDOID:0050700500.636
muscle tissue diseaseDOID:661130.636
dilated cardiomyopathyDOID:12930320.548
intrinsic cardiomyopathyDOID:0060036500.548
acquired metabolic diseaseDOID:0060158580.504
skin diseaseDOID:37330.308
integumentary system diseaseDOID:16430.308
diabetes mellitusDOID:9351310.251
carbohydrate metabolism diseaseDOID:0050013320.251
glucose metabolism diseaseDOID:4194320.251