Homo sapiens

88 known processes

ERCC8

excision repair cross-complementing rodent repair deficiency, complementation group 8

(Aliases: CSA,CKN1)

ERCC8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide excision repairGO:0006289310.862
ribonucleoside monophosphate catabolic processGO:00091581580.861
purine nucleoside monophosphate catabolic processGO:00091281580.860
cellular response to dna damage stimulusGO:00069743790.817
dna repairGO:00062811980.626
purine ribonucleoside monophosphate metabolic processGO:00091671860.571
ribonucleoside triphosphate metabolic processGO:00091994120.547
ribonucleoside triphosphate catabolic processGO:00092033910.543
purine nucleotide catabolic processGO:00061954050.530
purine ribonucleotide catabolic processGO:00091544040.501
purine nucleoside triphosphate catabolic processGO:00091463920.500
nucleoside catabolic processGO:00091644080.496
purine ribonucleoside triphosphate metabolic processGO:00092054110.484
purine ribonucleoside monophosphate catabolic processGO:00091691580.458
ribonucleoside monophosphate metabolic processGO:00091611870.449
purine ribonucleoside catabolic processGO:00461303980.446
nucleotide catabolic processGO:00091664080.446
ribonucleotide catabolic processGO:00092614050.426
atp catabolic processGO:00062001570.411
purine ribonucleoside triphosphate catabolic processGO:00092073910.409
nucleoside monophosphate catabolic processGO:00091251590.407
nucleoside triphosphate catabolic processGO:00091433940.399
organophosphate catabolic processGO:00464344300.392
positive regulation of cellular amine metabolic processGO:003324070.382
purine nucleoside monophosphate metabolic processGO:00091261860.381
atp metabolic processGO:00460341760.356
cellular amino acid metabolic processGO:00065201160.343
regulation of cellular amino acid metabolic processGO:000652160.335
purine nucleoside triphosphate metabolic processGO:00091444120.321
purine containing compound catabolic processGO:00725234110.306
regulation of cellular amine metabolic processGO:0033238110.302
nucleoside triphosphate metabolic processGO:00091414220.300
nucleoside monophosphate metabolic processGO:00091231910.298
nucleoside phosphate catabolic processGO:19012924120.295
ribonucleoside catabolic processGO:00424544060.272
positive regulation of cellular amino acid metabolic processGO:004576430.234
cellular amine metabolic processGO:0044106410.233
purine ribonucleoside metabolic processGO:00461284370.220
cellular ketone metabolic processGO:0042180800.219
purine nucleoside catabolic processGO:00061523980.218
glycosyl compound catabolic processGO:19016584130.175
positive regulation of protein phosphorylationGO:00019343130.164
amine metabolic processGO:0009308440.162
positive regulation of phosphorylationGO:00423273940.156
regulation of cellular ketone metabolic processGO:0010565500.146
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744180.092
positive regulation of transferase activityGO:00513472270.089
g protein coupled receptor signaling pathwayGO:00071862070.088
regulation of protein kinase activityGO:00458592890.088
positive regulation of kinase activityGO:00336742040.088
regulation of transferase activityGO:00513383550.074
regulation of peptidyl tyrosine phosphorylationGO:00507301080.069
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.069
post embryonic developmentGO:000979120.062
negative regulation of cell cycle processGO:00109481210.060
nucleic acid phosphodiester bond hydrolysisGO:00903051020.059
regulation of cell cycleGO:00517263930.058
positive regulation of protein kinase activityGO:00458601900.055
response to abiotic stimulusGO:00096283360.049
transcription coupled nucleotide excision repairGO:000628380.049
regulation of mitotic cell cycle phase transitionGO:19019901180.046
peptidyl tyrosine phosphorylationGO:00181081700.045
base excision repairGO:0006284210.039
vesicle mediated transportGO:00161923710.038
negative regulation of cell cycleGO:00457861930.038
receptor internalizationGO:0031623430.038
regulation of cell cycle processGO:00105642660.038
nervous system developmentGO:00073992930.034
determination of adult lifespanGO:000834020.034
proteolysis involved in cellular protein catabolic processGO:00516032440.034
mitotic cell cycle phase transitionGO:00447721620.033
peptidyl tyrosine modificationGO:00182121700.033
multicellular organismal agingGO:001025930.032
positive regulation of dna templated transcription elongationGO:0032786180.032
regulation of proteolysisGO:00301622930.032
cell cycle checkpointGO:00000751170.029
cellular macromolecule catabolic processGO:00442653800.029
positive regulation of protein tyrosine kinase activityGO:0061098240.029
mitotic cell cycleGO:00002783260.028
signal transduction by phosphorylationGO:00230142970.026
negative regulation of protein metabolic processGO:00512483910.025
female gamete generationGO:000729220.025
response to light stimulusGO:0009416870.025
dna integrity checkpointGO:0031570710.024
response to radiationGO:00093141510.024
double strand break repairGO:00063021010.024
positive regulation of hydrolase activityGO:00513453310.023
negative regulation of cell cycle phase transitionGO:1901988890.023
dephosphorylationGO:00163112090.022
regulation of mitotic cell cycleGO:00073461890.022
g protein coupled receptor internalizationGO:000203160.022
positive regulation of cell cycle processGO:00900681060.022
negative regulation of catalytic activityGO:00430863350.022
cell projection organizationGO:00300302520.021
adaptation of signaling pathwayGO:002305870.021
dna damage checkpointGO:0000077680.020
regulation of protein catabolic processGO:00421761550.020
posttranscriptional regulation of gene expressionGO:00106082130.020
negative regulation of cell proliferationGO:00082852280.020
regulation of meiotic cell cycleGO:005144540.019
negative regulation of cellular protein metabolic processGO:00322693530.019
ncrna metabolic processGO:00346601080.019
negative regulation of apoptotic processGO:00430663160.019
gtp metabolic processGO:00460392390.019
translationGO:00064121320.019
protein catabolic processGO:00301633250.019
receptor metabolic processGO:0043112810.019
response to uvGO:0009411730.018
lipid metabolic processGO:00066293810.018
rna processingGO:00063962550.018
organelle assemblyGO:00709251760.018
regulation of protein localizationGO:00328802960.018
microtubule based processGO:00070172100.018
cellular lipid metabolic processGO:00442553030.018
chromatin organizationGO:00063253510.018
cell morphogenesisGO:00009022960.017
single organism carbohydrate metabolic processGO:00447231930.017
apoptotic signaling pathwayGO:00971902680.017
microtubule cytoskeleton organizationGO:00002261760.017
regulation of protein serine threonine kinase activityGO:00719001790.017
negative regulation of protein maturationGO:19033181420.017
segmentationGO:003528240.016
regulation of protein tyrosine kinase activityGO:0061097360.016
mitotic cell cycle processGO:19030472860.016
regulation of protein transportGO:00512232130.016
response to oxidative stressGO:00069791210.016
adult locomotory behaviorGO:000834410.016
system processGO:00030083490.016
cellular macromolecular complex assemblyGO:00346223240.016
cell projection assemblyGO:00300311260.016
nuclear divisionGO:00002801280.016
protein maturationGO:00516042330.016
negative regulation of programmed cell deathGO:00430693210.016
chromosome segregationGO:00070591140.016
innate immune responseGO:00450871780.016
positive regulation of immune system processGO:00026842830.016
protein modification by small protein removalGO:0070646920.015
cell cycle phase transitionGO:00447701730.015
regulation of establishment of protein localizationGO:00702012420.015
cellular protein catabolic processGO:00442572610.015
methylationGO:00322591060.015
regulation of translationGO:0006417890.015
regulation of cell cycle phase transitionGO:19019871260.015
positive regulation of cellular component organizationGO:00511303760.015
cellular chemical homeostasisGO:00550821800.015
carbohydrate metabolic processGO:00059752070.015
positive regulation of transportGO:00510503360.015
negative regulation of intracellular signal transductionGO:19025321830.015
protein processingGO:00164852260.014
regulation of cellular response to stressGO:00801352440.014
locomotory behaviorGO:000762610.014
negative regulation of phosphorus metabolic processGO:00105632670.014
positive regulation of cell proliferationGO:00082843010.014
protein localization to organelleGO:00333652800.014
cell projection morphogenesisGO:00488581290.014
regulation of membrane potentialGO:0042391950.014
cation transmembrane transportGO:00986552380.014
cell divisionGO:00513011680.014
hindbrain developmentGO:003090230.014
histone modificationGO:00165702510.014
regulation of dna metabolic processGO:00510521530.014
regulation of protein maturationGO:19033171500.014
regulation of protein processingGO:00706131500.014
cellular response to abiotic stimulusGO:00712141170.013
regulation of mapk cascadeGO:00434082620.013
peripheral nervous system developmentGO:000742220.013
guanosine containing compound metabolic processGO:19010682440.013
ribonucleoprotein complex subunit organizationGO:0071826810.013
regulation of cytokine productionGO:00018172320.013
positive regulation of cell deathGO:00109422630.013
oogenesisGO:004847720.013
negative regulation of mitotic cell cycleGO:00459301020.013
negative regulation of protein modification processGO:00314002000.013
positive regulation of cell cycleGO:00457871400.013
ubiquitin dependent protein catabolic processGO:00065112060.013
defense responseGO:00069523150.013
cellular component morphogenesisGO:00329893140.013
mitotic nuclear divisionGO:00070671190.013
secretion by cellGO:00329402260.013
nerve developmentGO:002167540.013
metal ion homeostasisGO:00550651690.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
ncrna processingGO:0034470830.012
negative regulation of protein processingGO:00109551420.012
regulation of intracellular protein transportGO:00331571230.012
negative regulation of phosphorylationGO:00423261740.012
cell part morphogenesisGO:00329901370.012
positive regulation of cytokine productionGO:00018191670.012
anterior posterior axis specificationGO:000994820.012
negative regulation of phosphate metabolic processGO:00459362670.012
dna templated transcription elongationGO:0006354250.012
protein modification by small protein conjugationGO:00324463420.012
negative regulation of proteolysisGO:00458611320.012
single organism cellular localizationGO:19025803320.012
regenerationGO:003109940.012
regulation of dna templated transcription elongationGO:0032784230.012
trna metabolic processGO:0006399350.011
regulation of protein secretionGO:0050708860.011
regulation of kinase activityGO:00435493140.011
cellular carbohydrate metabolic processGO:0044262840.011
reproductive processGO:00224141060.011
neuromuscular junction developmentGO:000752830.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
cytokine productionGO:00018162470.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
covalent chromatin modificationGO:00165692540.011
response to woundingGO:00096111680.011
cellular homeostasisGO:00197251960.011
memoryGO:000761330.011
cellular cation homeostasisGO:00300031630.011
anatomical structure homeostasisGO:00602491000.011
mapk cascadeGO:00001652880.011
response to external biotic stimulusGO:00432072610.011
response to other organismGO:00517072610.011
dna replicationGO:00062601160.011
immune responseGO:00069553070.011
cranial nerve developmentGO:002154540.011
regulation of apoptotic signaling pathwayGO:20012331750.011
positive regulation of immune responseGO:00507781590.011
transmembrane transportGO:00550853990.011
trna processingGO:0008033230.011
ion homeostasisGO:00508012300.011
tissue regenerationGO:004224630.010
cellular response to uvGO:0034644320.010
positive regulation of protein serine threonine kinase activityGO:00719021190.010
negative regulation of cellular amine metabolic processGO:003323930.010
regulation of growthGO:00400081650.010
neurological system processGO:00508771630.010
neuron differentiationGO:00301821380.010
g2 dna damage checkpointGO:0031572260.010
cellular metal ion homeostasisGO:00068751460.010
negative regulation of cell deathGO:00605483450.010
positive regulation of organelle organizationGO:00106381950.010
inorganic ion transmembrane transportGO:00986602310.010

ERCC8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:56141490.528
eye and adnexa diseaseDOID:14921500.528
nervous system diseaseDOID:8634310.528
sensory system diseaseDOID:00501552030.528
retinal diseaseDOID:56791180.475
retinal degenerationDOID:8466890.475
macular degenerationDOID:4448200.125
disease of cellular proliferationDOID:145661740.122
organ system cancerDOID:00506861640.122
cancerDOID:1621670.122
age related macular degenerationDOID:10871170.106
degeneration of macula and posterior poleDOID:2007170.106
immune system diseaseDOID:29141550.019
disease of metabolismDOID:00146672950.017
respiratory system cancerDOID:0050615160.015
inherited metabolic disorderDOID:6552420.014
musculoskeletal system diseaseDOID:172230.010