Homo sapiens

201 known processes

ERCC2

excision repair cross-complementing rodent repair deficiency, complementation group 2

(Aliases: MGC126218,MGC102762,MGC126219,XPD,COFS2,EM9,TTD)

ERCC2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.130
glycosyl compound catabolic processGO:19016584130.120
purine nucleotide catabolic processGO:00061954050.117
nucleoside triphosphate metabolic processGO:00091414220.114
cellular amine metabolic processGO:0044106410.106
purine containing compound catabolic processGO:00725234110.101
purine nucleoside triphosphate catabolic processGO:00091463920.097
amine metabolic processGO:0009308440.096
regulation of cellular ketone metabolic processGO:0010565500.095
nucleoside phosphate catabolic processGO:19012924120.094
dna repairGO:00062811980.090
nucleotide excision repair dna incisionGO:003368370.088
purine nucleoside catabolic processGO:00061523980.086
nucleotide catabolic processGO:00091664080.081
regulation of cellular amino acid metabolic processGO:000652160.080
cellular response to dna damage stimulusGO:00069743790.079
purine ribonucleoside metabolic processGO:00461284370.078
purine nucleoside triphosphate metabolic processGO:00091444120.076
cellular ketone metabolic processGO:0042180800.073
regulation of cellular amine metabolic processGO:0033238110.072
ribonucleoside triphosphate catabolic processGO:00092033910.071
post embryonic developmentGO:000979120.070
purine ribonucleoside triphosphate metabolic processGO:00092054110.068
purine ribonucleoside catabolic processGO:00461303980.067
nucleoside triphosphate catabolic processGO:00091433940.066
ribonucleoside triphosphate metabolic processGO:00091994120.066
organophosphate catabolic processGO:00464344300.065
nucleotide excision repairGO:0006289310.064
purine ribonucleotide catabolic processGO:00091544040.063
nucleoside catabolic processGO:00091644080.062
purine ribonucleoside triphosphate catabolic processGO:00092073910.062
positive regulation of cellular amine metabolic processGO:003324070.061
ribonucleoside catabolic processGO:00424544060.060
regulation of transferase activityGO:00513383550.059
response to oxidative stressGO:00069791210.058
positive regulation of cellular amino acid metabolic processGO:004576430.054
purine ribonucleoside monophosphate metabolic processGO:00091671860.046
ribonucleotide catabolic processGO:00092614050.045
determination of adult lifespanGO:000834020.044
multicellular organismal agingGO:001025930.041
negative regulation of cellular protein metabolic processGO:00322693530.038
female gamete generationGO:000729220.037
purine nucleoside monophosphate catabolic processGO:00091281580.037
regulation of cell cycleGO:00517263930.037
ribonucleoside monophosphate catabolic processGO:00091581580.034
cellular macromolecule catabolic processGO:00442653800.034
cytoplasmic transportGO:00164823790.033
vesicle mediated transportGO:00161923710.033
negative regulation of protein metabolic processGO:00512483910.033
response to oxygen containing compoundGO:19017003690.033
negative regulation of catalytic activityGO:00430863350.032
carbohydrate metabolic processGO:00059752070.032
positive regulation of phosphorylationGO:00423273940.032
ras protein signal transductionGO:0007265730.031
positive regulation of protein phosphorylationGO:00019343130.031
atp catabolic processGO:00062001570.031
regulation of kinase activityGO:00435493140.031
protein modification by small protein conjugationGO:00324463420.030
ribonucleoside monophosphate metabolic processGO:00091611870.030
positive regulation of developmental processGO:00510943140.030
gtp metabolic processGO:00460392390.029
positive regulation of catabolic processGO:00098963100.029
atp metabolic processGO:00460341760.029
positive regulation of hydrolase activityGO:00513453310.028
guanosine containing compound metabolic processGO:19010682440.028
protein catabolic processGO:00301633250.028
apoptotic signaling pathwayGO:00971902680.027
nucleoside monophosphate catabolic processGO:00091251590.027
dna recombinationGO:0006310770.026
Yeast
regulation of nucleoside metabolic processGO:00091182090.026
regulation of protein kinase activityGO:00458592890.026
regulation of dna metabolic processGO:00510521530.026
Yeast
protein ubiquitinationGO:00165673140.026
oogenesisGO:004847720.025
regulation of purine nucleotide metabolic processGO:19005422640.025
purine nucleoside monophosphate metabolic processGO:00091261860.025
mapk cascadeGO:00001652880.025
response to radiationGO:00093141510.025
regulation of cellular response to stressGO:00801352440.025
histone modificationGO:00165702510.025
single organism carbohydrate metabolic processGO:00447231930.025
small gtpase mediated signal transductionGO:0007264780.024
regulation of mapk cascadeGO:00434082620.024
purine ribonucleoside monophosphate catabolic processGO:00091691580.024
positive regulation of cellular component organizationGO:00511303760.024
chromatin organizationGO:00063253510.024
locomotory behaviorGO:000762610.024
guanosine containing compound catabolic processGO:19010692390.024
cellular lipid metabolic processGO:00442553030.024
protein localization to organelleGO:00333652800.024
regulation of cell cycle processGO:00105642660.024
positive regulation of cellular catabolic processGO:00313312840.024
negative regulation of cellular component organizationGO:00511292350.023
system processGO:00030083490.023
regulation of mitotic cell cycleGO:00073461890.023
response to abiotic stimulusGO:00096283360.023
transmembrane transportGO:00550853990.023
regenerationGO:003109940.023
negative regulation of programmed cell deathGO:00430693210.023
posttranscriptional regulation of gene expressionGO:00106082130.023
regulation of cell growthGO:00015581350.023
negative regulation of apoptotic processGO:00430663160.022
covalent chromatin modificationGO:00165692540.022
gtp catabolic processGO:00061842370.022
regulation of wnt signaling pathwayGO:00301111230.022
negative regulation of phosphorus metabolic processGO:00105632670.022
nucleoside monophosphate metabolic processGO:00091231910.022
monocarboxylic acid metabolic processGO:00327871850.022
regulation of protein localizationGO:00328802960.022
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of organelle organizationGO:00106391260.021
negative regulation of cellular amine metabolic processGO:003323930.021
epithelium developmentGO:00604292270.021
segmentationGO:003528240.021
negative regulation of phosphate metabolic processGO:00459362670.021
chemical homeostasisGO:00488783060.021
actin filament based processGO:00300292240.021
cellular protein catabolic processGO:00442572610.021
peptidyl tyrosine phosphorylationGO:00181081700.021
positive regulation of transferase activityGO:00513472270.021
protein processingGO:00164852260.021
nitrogen compound transportGO:00717051910.021
lipid metabolic processGO:00066293810.021
regulation of secretion by cellGO:19035301770.021
regulation of proteolysisGO:00301622930.020
positive regulation of immune system processGO:00026842830.020
lipid biosynthetic processGO:00086101770.020
regulation of nucleotide metabolic processGO:00061402690.020
peptidyl tyrosine modificationGO:00182121700.020
cation transportGO:00068123310.020
immune responseGO:00069553070.020
meiotic chromosome segregationGO:004513240.020
regulation of secretionGO:00510461940.020
anatomical structure homeostasisGO:00602491000.019
protein maturationGO:00516042330.019
mitotic cell cycleGO:00002783260.019
regulation of cellular component biogenesisGO:00440872810.019
regulation of nucleotide catabolic processGO:00308112050.019
cell activationGO:00017752130.019
secretion by cellGO:00329402260.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
biological adhesionGO:00226103310.019
single organism cellular localizationGO:19025803320.019
regulation of locomotionGO:00400123290.019
negative regulation of phosphorylationGO:00423261740.019
positive regulation of nucleotide metabolic processGO:00459812300.019
positive regulation of transportGO:00510503360.019
negative regulation of protein modification processGO:00314002000.019
protein oligomerizationGO:00512591730.019
signal transduction by phosphorylationGO:00230142970.019
endocytosisGO:00068971590.018
intracellular protein transportGO:00068862700.018
cell projection organizationGO:00300302520.018
regulation of gtp catabolic processGO:00331241800.018
cellular component morphogenesisGO:00329893140.018
chromosome segregationGO:00070591140.018
regulation of purine nucleotide catabolic processGO:00331212050.018
dephosphorylationGO:00163112090.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
negative regulation of transportGO:00510511760.018
chromatin modificationGO:00165682980.018
positive regulation of cell deathGO:00109422630.018
negative regulation of cell deathGO:00605483450.018
defense responseGO:00069523150.018
limbic system developmentGO:002176130.018
cell cycle phase transitionGO:00447701730.017
innate immune responseGO:00450871780.017
neuromuscular junction developmentGO:000752830.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
organonitrogen compound biosynthetic processGO:19015662000.017
response to other organismGO:00517072610.017
endomembrane system organizationGO:00102561960.017
spermatid differentiationGO:004851540.017
cardiovascular system developmentGO:00723582620.017
positive regulation of programmed cell deathGO:00430682490.017
negative regulation of homeostatic processGO:0032845590.017
regulation of cell motilityGO:20001452990.017
regulation of immune responseGO:00507762010.016
cell morphogenesisGO:00009022960.016
endosomal transportGO:00161971290.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of homeostatic processGO:00328441210.016
mitotic cell cycle phase transitionGO:00447721620.016
rna processingGO:00063962550.016
nuclear transportGO:00511691790.016
cellular response to endogenous stimulusGO:00714953360.016
regulation of protein transportGO:00512232130.016
maintenance of locationGO:00512351120.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
positive regulation of apoptotic processGO:00430652460.016
positive regulation of nucleotide catabolic processGO:00308131850.016
positive regulation of cell differentiationGO:00455972110.016
membrane organizationGO:00610242920.015
regulation of anatomical structure morphogenesisGO:00226032860.015
response to decreased oxygen levelsGO:0036293960.015
cell growthGO:00160491600.015
microtubule based processGO:00070172100.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
nucleic acid phosphodiester bond hydrolysisGO:00903051020.015
microtubule cytoskeleton organizationGO:00002261760.015
cell divisionGO:00513011680.015
ion homeostasisGO:00508012300.015
regulation of cell differentiationGO:00455953930.015
regulation of establishment of protein localizationGO:00702012420.015
regulation of gtpase activityGO:00430871800.015
neurogenesisGO:00220081690.015
regulation of cellular component movementGO:00512703340.015
regulation of hormone levelsGO:00108171250.015
regulation of ras gtpase activityGO:00323181280.015
regulation of chromosome organizationGO:00330441030.015
cellular response to cytokine stimulusGO:00713451810.015
organic acid biosynthetic processGO:0016053970.015
proteasomal protein catabolic processGO:00104981760.015
nucleocytoplasmic transportGO:00069131760.014
modification dependent protein catabolic processGO:00199412090.014
regulation of protein serine threonine kinase activityGO:00719001790.014
response to oxygen levelsGO:00704821000.014
oocyte differentiationGO:000999420.014
protein modification by small protein removalGO:0070646920.014
protein localization to nucleusGO:00345041360.014
cell projection morphogenesisGO:00488581290.014
regulation of growthGO:00400081650.014
rho protein signal transductionGO:0007266260.014
nervous system developmentGO:00073992930.014
regulation of synaptic plasticityGO:004816730.014
protein targetingGO:00066051870.014
regulation of response to external stimulusGO:00321012220.014
carbohydrate derivative biosynthetic processGO:19011372070.014
mrna metabolic processGO:00160711750.014
single organism membrane organizationGO:00448022680.014
negative regulation of protein maturationGO:19033181420.014
cellular response to growth factor stimulusGO:00713631970.014
response to woundingGO:00096111680.014
oocyte developmentGO:004859910.014
regulation of intracellular transportGO:00323861950.014
negative regulation of cell cycleGO:00457861930.014
establishment of protein localization to organelleGO:00725941720.014
negative regulation of transferase activityGO:00513481240.014
cellular response to oxygen containing compoundGO:19017012760.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of cell migrationGO:00303342890.014
organelle fissionGO:00482851490.014
growthGO:00400072020.013
immune system developmentGO:00025201950.013
ion transmembrane transportGO:00342203380.013
positive regulation of gtp catabolic processGO:00331261660.013
response to cytokineGO:00340972320.013
regulation of protein catabolic processGO:00421761550.013
positive regulation of cellular component biogenesisGO:00440891580.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of peptidase activityGO:00525471800.013
response to uvGO:0009411730.013
response to lipidGO:00339932060.013
metal ion transportGO:00300012720.013
carboxylic acid biosynthetic processGO:0046394970.013
negative regulation of cell proliferationGO:00082852280.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
negative regulation of dna metabolic processGO:0051053570.013
ubiquitin dependent protein catabolic processGO:00065112060.013
response to biotic stimulusGO:00096072760.013
regulation of protein maturationGO:19033171500.013
negative regulation of proteolysisGO:00458611320.013
blastoderm segmentationGO:000735020.013
protein autophosphorylationGO:00467771230.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
spermatid developmentGO:000728640.013
negative regulation of protein processingGO:00109551420.013
cellular response to oxidative stressGO:0034599850.013
regulation of protein processingGO:00706131500.013
cell fate determinationGO:000170930.012
positive regulation of kinase activityGO:00336742040.012
cell part morphogenesisGO:00329901370.012
circulatory system developmentGO:00723592620.012
response to external biotic stimulusGO:00432072610.012
cell developmentGO:00484683280.012
negative regulation of growthGO:0045926970.012
response to axon injuryGO:004867810.012
regulation of apoptotic signaling pathwayGO:20012331750.012
regulation of cytoskeleton organizationGO:00514931770.012
embryo developmentGO:00097901230.012
small molecule biosynthetic processGO:00442831570.012
lens development in camera type eyeGO:000208820.012
positive regulation of immune responseGO:00507781590.012
positive regulation of organelle organizationGO:00106381950.012
cellular response to lipidGO:00713961270.012
protein deubiquitinationGO:0016579790.012
cellular homeostasisGO:00197251960.012
adult locomotory behaviorGO:000834410.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
negative regulation of developmental processGO:00510932470.012
modification dependent macromolecule catabolic processGO:00436322120.012
protein localization to membraneGO:00726571600.012
rna interferenceGO:001624640.012
anterior posterior axis specificationGO:000994820.012
cilium morphogenesisGO:0060271750.012
response to hypoxiaGO:0001666960.012
negative regulation of protein phosphorylationGO:00019331400.012
cell adhesionGO:00071553250.012
cellular chemical homeostasisGO:00550821800.012
regulation of cell morphogenesisGO:00226041530.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
positive regulation of mapk cascadeGO:00434101900.012
positive regulation of protein transportGO:00512221350.012
regulation of cytoplasmic transportGO:19036491490.012
hippocampus developmentGO:002176610.012
negative regulation of hydrolase activityGO:00513461820.012
glycoprotein biosynthetic processGO:0009101910.012
translationGO:00064121320.012
mitochondrion organizationGO:00070051560.012
regulation of cell cycle phase transitionGO:19019871260.012
negative regulation of multicellular organismal processGO:00512413170.012
phosphorylation of rna polymerase ii c terminal domainGO:007081630.012
Yeast
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
mitotic cell cycle processGO:19030472860.011
morphogenesis of embryonic epitheliumGO:001633140.011
oxidation reduction processGO:00551143960.011
positive regulation of gtpase activityGO:00435471660.011
secretionGO:00469032540.011
immune effector processGO:00022521590.011
double strand break repairGO:00063021010.011
single organism cell adhesionGO:00986021790.011
positive regulation of protein kinase activityGO:00458601900.011
rna splicingGO:00083801310.011
memoryGO:000761330.011
neuron differentiationGO:00301821380.011
leukocyte activationGO:00453211640.011
negative regulation of chromosome organizationGO:2001251480.011
negative regulation of protein kinase activityGO:0006469980.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
reactive oxygen species metabolic processGO:0072593750.011
developmental programmed cell deathGO:001062330.011
regulation of protein complex assemblyGO:00432541470.011
glycoprotein metabolic processGO:00091001100.011
cell morphogenesis involved in differentiationGO:00009041440.011
activation of immune responseGO:00022531140.011
interspecies interaction between organismsGO:00444191560.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
regulation of vesicle mediated transportGO:00606271300.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
neurological system processGO:00508771630.011
response to virusGO:00096151260.011
receptor mediated endocytosisGO:0006898840.011
regulation of defense responseGO:00313471540.011
response to growth factorGO:00708482050.011
negative regulation of kinase activityGO:00336731060.011
fatty acid metabolic processGO:00066311150.011
blastocyst formationGO:000182530.011
reproductive processGO:00224141060.011
regulation of ras protein signal transductionGO:00465781550.011
neural tube formationGO:000184130.011
compound eye developmentGO:004874910.011
peptidyl serine phosphorylationGO:00181051010.011
regulation of protein stabilityGO:0031647870.011
regulation of cytokine productionGO:00018172320.011
regulation of cell adhesionGO:00301551660.011
response to organic cyclic compoundGO:00140702040.011
cation homeostasisGO:00550801890.010
cellular protein complex assemblyGO:00436231880.010
regulation of cell developmentGO:00602841610.010
embryonic epithelial tube formationGO:000183840.010
sequestering of metal ionGO:0051238240.010
motor neuron axon guidanceGO:000804520.010
peptidyl serine modificationGO:00182091060.010
response to inorganic substanceGO:00100351270.010
epithelial cell differentiationGO:00308551410.010
epithelial cell proliferationGO:00506731280.010
cytokine productionGO:00018162470.010
positive regulation of cell proliferationGO:00082843010.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
generation of precursor metabolites and energyGO:0006091680.010
response to organonitrogen compoundGO:00102431560.010
cytokinesisGO:0000910960.010
actin cytoskeleton organizationGO:00300362070.010
protein secretionGO:0009306980.010
cytokine mediated signaling pathwayGO:00192211090.010
actin filament organizationGO:00070151280.010
response to hormoneGO:00097251750.010
regulation of ion transportGO:00432691890.010
hindbrain developmentGO:003090230.010
negative regulation of cell cycle processGO:00109481210.010
single organism reproductive processGO:0044702980.010
protein acylationGO:00435431380.010

ERCC2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.052
cancerDOID:1621670.050
organ system cancerDOID:00506861640.036
disease of metabolismDOID:00146672950.036
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.028
musculoskeletal system diseaseDOID:172230.028
central nervous system diseaseDOID:3311860.026
inherited metabolic disorderDOID:6552420.020
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.019
retinal diseaseDOID:56791180.019
connective tissue diseaseDOID:651090.017
immune system diseaseDOID:29141550.015
neurodegenerative diseaseDOID:12891020.015
brain diseaseDOID:936730.014
electroclinical syndromeDOID:0050701320.014
neonatal period electroclinical syndromeDOID:0050702190.014
epilepsy syndromeDOID:1826410.014
retinal degenerationDOID:8466890.013
bone diseaseDOID:0080001880.012
carbohydrate metabolic disorderDOID:2978550.012
muscular diseaseDOID:00800001140.010
muscle tissue diseaseDOID:661130.010
xeroderma pigmentosumDOID:005042780.004
photosensitive trichothiodystrophyDOID:296030.001