Homo sapiens

103 known processes

ERCC4

excision repair cross-complementing rodent repair deficiency, complementation group 4

(Aliases: ERCC11,XPF,RAD1)

ERCC4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via single strand annealingGO:004500240.603
nucleotide excision repairGO:0006289310.479
nucleotide excision repair dna incisionGO:003368370.191
cellular response to dna damage stimulusGO:00069743790.186
cellular macromolecule catabolic processGO:00442653800.157
regulation of telomere maintenanceGO:0032204130.140
response to cell cycle checkpoint signalingGO:007239640.133
post embryonic developmentGO:000979120.130
dna catabolic process endonucleolyticGO:0000737370.112
dna recombinationGO:0006310770.111
regulation of mitotic cell cycleGO:00073461890.102
dna repairGO:00062811980.096
cellular amino acid metabolic processGO:00065201160.089
negative regulation of cell cycle phase transitionGO:1901988890.080
dna catabolic processGO:0006308490.077
negative regulation of mitotic cell cycleGO:00459301020.073
regulation of cellular amine metabolic processGO:0033238110.072
regulation of cell cycleGO:00517263930.070
negative regulation of organelle organizationGO:00106391260.070
nucleic acid phosphodiester bond hydrolysisGO:00903051020.068
nucleoside triphosphate metabolic processGO:00091414220.066
regulation of dna metabolic processGO:00510521530.063
regulation of cellular ketone metabolic processGO:0010565500.063
response to biotic stimulusGO:00096072760.061
amine metabolic processGO:0009308440.061
positive regulation of cellular amino acid metabolic processGO:004576430.060
mitotic cell cycleGO:00002783260.058
regulation of cellular amino acid metabolic processGO:000652160.058
positive regulation of cellular amine metabolic processGO:003324070.052
negative regulation of cell cycle processGO:00109481210.052
cellular amine metabolic processGO:0044106410.052
negative regulation of cell cycleGO:00457861930.051
nucleotide catabolic processGO:00091664080.047
negative regulation of dna metabolic processGO:0051053570.047
cellular ketone metabolic processGO:0042180800.047
nucleoside triphosphate catabolic processGO:00091433940.045
dna integrity checkpointGO:0031570710.044
recombinational repairGO:0000725500.043
response to dna integrity checkpoint signalingGO:007240240.043
positive regulation of catabolic processGO:00098963100.042
oogenesisGO:004847720.041
protein catabolic processGO:00301633250.040
multicellular organismal agingGO:001025930.039
female gamete generationGO:000729220.039
negative regulation of protein metabolic processGO:00512483910.038
morphogenesis of embryonic epitheliumGO:001633140.038
positive regulation of hydrolase activityGO:00513453310.037
mitotic cell cycle checkpointGO:0007093680.035
negative regulation of homeostatic processGO:0032845590.035
positive regulation of cell deathGO:00109422630.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
double strand break repair via homologous recombinationGO:0000724500.034
purine ribonucleotide catabolic processGO:00091544040.034
purine nucleotide catabolic processGO:00061954050.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
purine nucleoside triphosphate metabolic processGO:00091444120.033
epithelium developmentGO:00604292270.033
negative regulation of chromosome organizationGO:2001251480.032
nucleoside phosphate catabolic processGO:19012924120.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
negative regulation of catalytic activityGO:00430863350.031
organophosphate catabolic processGO:00464344300.031
actomyosin contractile ring organizationGO:004483710.031
negative regulation of programmed cell deathGO:00430693210.031
regulation of cell cycle processGO:00105642660.031
purine ribonucleoside metabolic processGO:00461284370.030
regulation of cellular component biogenesisGO:00440872810.029
cellular protein complex assemblyGO:00436231880.029
ribonucleoside catabolic processGO:00424544060.029
transmembrane transportGO:00550853990.029
proteolysis involved in cellular protein catabolic processGO:00516032440.029
purine ribonucleoside catabolic processGO:00461303980.029
cell cycle phase transitionGO:00447701730.028
determination of adult lifespanGO:000834020.028
anatomical structure homeostasisGO:00602491000.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
response to radiationGO:00093141510.027
protein localization to organelleGO:00333652800.027
negative regulation of cell deathGO:00605483450.027
negative regulation of phosphorus metabolic processGO:00105632670.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
actin filament based processGO:00300292240.026
negative regulation of cellular protein metabolic processGO:00322693530.026
purine containing compound catabolic processGO:00725234110.026
gtp metabolic processGO:00460392390.026
oocyte differentiationGO:000999420.026
mitotic cell cycle processGO:19030472860.026
protein maturationGO:00516042330.026
intracellular protein transportGO:00068862700.026
ubiquitin dependent protein catabolic processGO:00065112060.026
negative regulation of catabolic processGO:00098951040.026
glycosyl compound catabolic processGO:19016584130.025
negative regulation of phosphate metabolic processGO:00459362670.025
negative regulation of apoptotic processGO:00430663160.025
ribonucleotide catabolic processGO:00092614050.025
positive regulation of transportGO:00510503360.025
response to oxygen containing compoundGO:19017003690.024
response to abiotic stimulusGO:00096283360.024
regulation of proteolysisGO:00301622930.024
cellular response to endogenous stimulusGO:00714953360.024
i kappab kinase nf kappab signalingGO:00072491660.024
regulation of protein kinase activityGO:00458592890.024
positive regulation of cellular component organizationGO:00511303760.024
regulation of mitotic cell cycle phase transitionGO:19019901180.023
response to dna damage checkpoint signalingGO:007242340.023
cytoplasmic transportGO:00164823790.023
regulation of cell differentiationGO:00455953930.023
regulation of purine nucleotide catabolic processGO:00331212050.023
regulation of kinase activityGO:00435493140.023
dna catabolic process exonucleolyticGO:0000738170.023
spermatid differentiationGO:004851540.023
positive regulation of protein phosphorylationGO:00019343130.023
positive regulation of phosphorylationGO:00423273940.023
dephosphorylationGO:00163112090.022
dna double strand break processingGO:0000729100.022
regulation of meiotic cell cycleGO:005144540.022
microtubule based processGO:00070172100.022
regulation of nucleotide metabolic processGO:00061402690.022
dna damage checkpointGO:0000077680.022
regulation of protein catabolic processGO:00421761550.022
nucleoside catabolic processGO:00091644080.022
guanosine containing compound metabolic processGO:19010682440.022
regulation of transferase activityGO:00513383550.022
positive regulation of apoptotic processGO:00430652460.021
negative regulation of cellular catabolic processGO:0031330830.021
embryonic epithelial tube formationGO:000183840.021
protein modification by small protein conjugationGO:00324463420.021
positive regulation of cell cycle processGO:00900681060.021
modification dependent macromolecule catabolic processGO:00436322120.021
regulation of nucleotide catabolic processGO:00308112050.021
biological adhesionGO:00226103310.021
positive regulation of cellular catabolic processGO:00313312840.021
negative regulation of telomere maintenanceGO:003220590.021
cellular response to biotic stimulusGO:0071216710.021
negative regulation of proteolysisGO:00458611320.021
protein ubiquitinationGO:00165673140.021
gtp catabolic processGO:00061842370.021
regulation of protein processingGO:00706131500.021
positive regulation of protein transportGO:00512221350.020
rho protein signal transductionGO:0007266260.020
guanosine containing compound catabolic processGO:19010692390.020
neuroblast proliferationGO:000740540.020
vesicle mediated transportGO:00161923710.020
immune responseGO:00069553070.020
mitotic cell cycle phase transitionGO:00447721620.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of nucleoside metabolic processGO:00459791860.020
defense responseGO:00069523150.020
locomotory behaviorGO:000762610.020
regulation of purine nucleotide metabolic processGO:19005422640.020
signal transduction by phosphorylationGO:00230142970.020
cell morphogenesisGO:00009022960.020
ras protein signal transductionGO:0007265730.020
proteasomal protein catabolic processGO:00104981760.020
regulation of establishment of protein localizationGO:00702012420.020
single organism membrane organizationGO:00448022680.020
regulation of intracellular transportGO:00323861950.020
regulation of cell cycle phase transitionGO:19019871260.020
nitrogen compound transportGO:00717051910.019
anterior posterior axis specificationGO:000994820.019
positive regulation of organelle organizationGO:00106381950.019
protein processingGO:00164852260.019
segmentationGO:003528240.019
spermatid developmentGO:000728640.019
positive regulation of nucleotide metabolic processGO:00459812300.019
purine nucleoside catabolic processGO:00061523980.019
cellular component morphogenesisGO:00329893140.019
mitotic dna damage checkpointGO:0044773280.019
regulation of protein transportGO:00512232130.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
release of cytoplasmic sequestered nf kappabGO:000858840.018
small gtpase mediated signal transductionGO:0007264780.018
cell divisionGO:00513011680.018
regulation of neural precursor cell proliferationGO:200017740.018
cellular protein catabolic processGO:00442572610.018
ion transmembrane transportGO:00342203380.018
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.018
meiosis iGO:000712740.018
regulation of meiosisGO:004002030.018
negative regulation of protein phosphorylationGO:00019331400.018
negative regulation of protein modification processGO:00314002000.018
g2 m transition of mitotic cell cycleGO:0000086410.017
response to oxidative stressGO:00069791210.017
negative regulation of mitotic cell cycle phase transitionGO:1901991850.017
negative regulation of intracellular signal transductionGO:19025321830.017
cellular lipid metabolic processGO:00442553030.017
metal ion transportGO:00300012720.017
memoryGO:000761330.017
regulation of nucleoside metabolic processGO:00091182090.017
regulation of homeostatic processGO:00328441210.017
mapk cascadeGO:00001652880.017
positive regulation of gtpase activityGO:00435471660.017
regulation of cellular protein catabolic processGO:1903362960.017
neuromuscular junction developmentGO:000752830.017
oocyte developmentGO:004859910.017
regulation of cytoskeleton organizationGO:00514931770.017
hindbrain developmentGO:003090230.017
response to woundingGO:00096111680.017
cell cycle checkpointGO:00000751170.017
positive regulation of purine nucleotide metabolic processGO:19005442270.016
microtubule cytoskeleton organizationGO:00002261760.016
sex determinationGO:000753030.016
negative regulation of phosphorylationGO:00423261740.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
intra s dna damage checkpointGO:003157340.016
regulation of gtp catabolic processGO:00331241800.016
positive regulation of nucleotide catabolic processGO:00308131850.016
cell adhesionGO:00071553250.016
membrane organizationGO:00610242920.016
negative regulation of developmental processGO:00510932470.016
cell type specific apoptotic processGO:00972851250.015
peripheral nervous system developmentGO:000742220.015
negative regulation of protein processingGO:00109551420.015
positive regulation of transferase activityGO:00513472270.015
actin cytoskeleton organizationGO:00300362070.015
lipid metabolic processGO:00066293810.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
cation transportGO:00068123310.015
protein targetingGO:00066051870.015
regulation of protein complex assemblyGO:00432541470.015
negative regulation of cellular amine metabolic processGO:003323930.015
salivary gland morphogenesisGO:000743540.015
posttranscriptional regulation of gene expressionGO:00106082130.015
cell developmentGO:00484683280.015
maintenance of locationGO:00512351120.015
negative regulation of cell proliferationGO:00082852280.015
nervous system developmentGO:00073992930.015
regulation of gtpase activityGO:00430871800.015
positive regulation of cell proliferationGO:00082843010.015
system processGO:00030083490.015
organelle fissionGO:00482851490.015
positive regulation of intracellular transportGO:00323881040.015
negative regulation of multicellular organismal processGO:00512413170.014
positive regulation of programmed cell deathGO:00430682490.014
non recombinational repairGO:0000726140.014
positive regulation of cell cycleGO:00457871400.014
regulation of locomotionGO:00400123290.014
regulation of response to external stimulusGO:00321012220.014
single organism cellular localizationGO:19025803320.014
cell part morphogenesisGO:00329901370.014
regulation of intracellular protein transportGO:00331571230.014
negative regulation of protein maturationGO:19033181420.014
positive regulation of gtp catabolic processGO:00331261660.014
protein oligomerizationGO:00512591730.014
regulation of protein maturationGO:19033171500.014
regulation of neuroblast proliferationGO:190269230.014
organelle assemblyGO:00709251760.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
regulation of anatomical structure morphogenesisGO:00226032860.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
regulation of protein localizationGO:00328802960.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
establishment of nucleus localizationGO:004002310.014
regulation of cell migrationGO:00303342890.014
innate immune responseGO:00450871780.014
protein localization to nucleusGO:00345041360.014
nucleoside monophosphate metabolic processGO:00091231910.014
cell projection organizationGO:00300302520.014
regulation of cell motilityGO:20001452990.014
reciprocal dna recombinationGO:003582540.014
regulation of mapk cascadeGO:00434082620.013
establishment of protein localization to organelleGO:00725941720.013
negative regulation of transferase activityGO:00513481240.013
epithelial cell differentiationGO:00308551410.013
blastoderm segmentationGO:000735020.013
response to uvGO:0009411730.013
primary neural tube formationGO:001402030.013
cellular macromolecular complex assemblyGO:00346223240.013
compound eye developmentGO:004874910.013
tripartite regional subdivisionGO:000735120.013
positive regulation of cellular component biogenesisGO:00440891580.013
negative regulation of stem cell proliferationGO:200064730.013
regulation of proteasomal protein catabolic processGO:0061136870.013
metencephalon developmentGO:002203720.013
nucleus localizationGO:005164710.013
reciprocal meiotic recombinationGO:000713140.013
response to ionizing radiationGO:0010212650.013
double strand break repairGO:00063021010.013
photoreceptor cell differentiationGO:004653020.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
modification dependent protein catabolic processGO:00199412090.013
response to lipidGO:00339932060.013
regulation of cell developmentGO:00602841610.013
inorganic ion transmembrane transportGO:00986602310.013
regulation of protein stabilityGO:0031647870.013
inner ear morphogenesisGO:004247240.013
neural tube closureGO:000184330.013
immune effector processGO:00022521590.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
morphogenesis of a polarized epitheliumGO:000173830.012
positive regulation of kinase activityGO:00336742040.012
oxidation reduction processGO:00551143960.012
regulation of ras gtpase activityGO:00323181280.012
neurotransmitter secretionGO:000726940.012
endosomal transportGO:00161971290.012
protein autophosphorylationGO:00467771230.012
cell projection assemblyGO:00300311260.012
negative regulation of kinase activityGO:00336731060.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
organophosphate biosynthetic processGO:00904071630.012
negative regulation of hydrolase activityGO:00513461820.012
negative regulation of cellular component organizationGO:00511292350.012
nucleocytoplasmic transportGO:00069131760.012
peptidyl tyrosine modificationGO:00182121700.012
chemical homeostasisGO:00488783060.012
peptidyl tyrosine phosphorylationGO:00181081700.012
embryo developmentGO:00097901230.012
taxisGO:00423301570.012
male meiosisGO:000714010.012
regulation of synaptic plasticityGO:004816730.012
cytokinesisGO:0000910960.012
regulation of cellular component movementGO:00512703340.012
regulation of bindingGO:00510981110.012
reactive oxygen species metabolic processGO:0072593750.012
negative regulation of transportGO:00510511760.012
anterior posterior axis specification embryoGO:000859520.012
motor neuron axon guidanceGO:000804520.012
anion transportGO:00068201610.012
interspecies interaction between organismsGO:00444191560.012
cellular homeostasisGO:00197251960.012
cellular response to oxygen containing compoundGO:19017012760.011
peptidyl lysine modificationGO:00182051440.011
positive regulation of protein kinase activityGO:00458601900.011
single organismal cell cell adhesionGO:00163371480.011
response to cytokineGO:00340972320.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
negative regulation of neural precursor cell proliferationGO:200017810.011
wnt signaling pathwayGO:00160551560.011
cilium morphogenesisGO:0060271750.011
apoptotic signaling pathwayGO:00971902680.011
anion transmembrane transportGO:0098656760.011
nuclear transportGO:00511691790.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
regulation of immune responseGO:00507762010.011
generation of neuronsGO:00486991520.011
reactive oxygen species biosynthetic processGO:190340940.011
myosin filament assemblyGO:003103420.011
response to axon injuryGO:004867810.011
leukocyte activationGO:00453211640.011
sequestering of metal ionGO:0051238240.011
reproductive processGO:00224141060.011
autophagyGO:0006914880.011
negative regulation of protein kinase activityGO:0006469980.011
sensory perception of painGO:001923340.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
syncytium formation by plasma membrane fusionGO:000076820.011
telomere maintenanceGO:0000723320.011
response to external biotic stimulusGO:00432072610.011
positive regulation of ras gtpase activityGO:00323201170.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
single organism cell adhesionGO:00986021790.011
sequestering of calcium ionGO:0051208170.011
protein homooligomerizationGO:00512601000.011
visual behaviorGO:000763220.011
cell activationGO:00017752130.011
organ formationGO:004864530.011
regulation of protein bindingGO:0043393660.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
receptor metabolic processGO:0043112810.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
positive regulation of immune system processGO:00026842830.011
single organism nuclear importGO:19025931040.011
organonitrogen compound biosynthetic processGO:19015662000.011
neural tube formationGO:000184130.011
rna processingGO:00063962550.011
rhythmic behaviorGO:000762220.011
chromatin organizationGO:00063253510.011
long term memoryGO:000761620.011
lung alveolus developmentGO:004828640.011
cerebellum developmentGO:002154920.010
lipid biosynthetic processGO:00086101770.010
regulation of cell morphogenesisGO:00226041530.010
protein localization to membraneGO:00726571600.010
negative regulation of gliogenesisGO:001401430.010
cation homeostasisGO:00550801890.010
hemopoiesisGO:00300971800.010
negative regulation of jun kinase activityGO:004350840.010
adult locomotory behaviorGO:000834410.010
positive regulation of intracellular protein transportGO:0090316760.010
regulation of cytoplasmic transportGO:19036491490.010
protein acylationGO:00435431380.010
regulation of secretionGO:00510461940.010
reactive nitrogen species metabolic processGO:200105730.010
inorganic cation transmembrane transportGO:00986621940.010
endocytosisGO:00068971590.010
regulation of response to woundingGO:19030341010.010
response to light stimulusGO:0009416870.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
positive regulation of cellular component movementGO:00512721810.010
actin filament based movementGO:0030048170.010
sensory perceptionGO:00076001030.010
regulation of microtubule based processGO:0032886740.010

ERCC4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
anemiaDOID:2355550.333
hematopoietic system diseaseDOID:741000.333
aplastic anemiaDOID:12449300.333
bone marrow diseaseDOID:4961310.333
immune system diseaseDOID:29141550.333
disease of metabolismDOID:00146672950.032
cancerDOID:1621670.031
disease of cellular proliferationDOID:145661740.031
organ system cancerDOID:00506861640.026
nervous system diseaseDOID:8634310.025
sensory system diseaseDOID:00501552030.025
connective tissue diseaseDOID:651090.022
musculoskeletal system diseaseDOID:172230.022
inherited metabolic disorderDOID:6552420.021
eye diseaseDOID:56141490.020
eye and adnexa diseaseDOID:14921500.020
central nervous system diseaseDOID:3311860.018
retinal diseaseDOID:56791180.017
retinal degenerationDOID:8466890.014
bone diseaseDOID:0080001880.012
brain diseaseDOID:936730.010
muscular diseaseDOID:00800001140.010
cardiovascular system diseaseDOID:12871060.010
congenital hypoplastic anemiaDOID:1342260.010
fanconi s anemiaDOID:13636160.010
xeroderma pigmentosumDOID:005042780.005