Homo sapiens

203 known processes

ERCC6

excision repair cross-complementing rodent repair deficiency, complementation group 6

(Aliases: RAD26,ARMD5,COFS,CKN2,CSB,COFS1)

ERCC6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleotide excision repairGO:0006289310.968
transcription coupled nucleotide excision repairGO:000628380.957
dna repairGO:00062811980.942
cellular response to dna damage stimulusGO:00069743790.908
response to light stimulusGO:0009416870.616
cellular macromolecule catabolic processGO:00442653800.589
response to abiotic stimulusGO:00096283360.537
response to radiationGO:00093141510.519
positive regulation of response to dna damage stimulusGO:2001022430.447
protein autoubiquitinationGO:0051865370.438
regulation of dna repairGO:0006282470.430
modification dependent macromolecule catabolic processGO:00436322120.423
modification dependent protein catabolic processGO:00199412090.380
protein ubiquitinationGO:00165673140.376
protein polyubiquitinationGO:00002091100.349
proteolysis involved in cellular protein catabolic processGO:00516032440.320
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.319
cellular protein catabolic processGO:00442572610.279
ubiquitin dependent protein catabolic processGO:00065112060.275
protein modification by small protein conjugationGO:00324463420.266
positive regulation of dna metabolic processGO:0051054730.250
protein catabolic processGO:00301633250.233
response to ionizing radiationGO:0010212650.205
proteasomal protein catabolic processGO:00104981760.171
nucleic acid phosphodiester bond hydrolysisGO:00903051020.166
positive regulation of dna repairGO:0045739250.149
dna damage checkpointGO:0000077680.117
chromatin organizationGO:00063253510.104
cell cycle checkpointGO:00000751170.098
post embryonic developmentGO:000979120.093
rna processingGO:00063962550.091
response to oxidative stressGO:00069791210.084
regulation of cell cycleGO:00517263930.084
response to uvGO:0009411730.080
regulation of cellular response to stressGO:00801352440.078
regulation of cell cycle phase transitionGO:19019871260.074
regulation of response to dna damage stimulusGO:2001020940.072
cellular response to abiotic stimulusGO:00712141170.071
interspecies interaction between organismsGO:00444191560.070
vesicle mediated transportGO:00161923710.068
postreplication repairGO:0006301120.063
purine nucleotide catabolic processGO:00061954050.059
digestive system developmentGO:0055123750.057
steroid metabolic processGO:0008202940.057
purine nucleoside catabolic processGO:00061523980.056
regulation of proteolysisGO:00301622930.054
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.054
microtubule cytoskeleton organizationGO:00002261760.053
mitotic cell cycle phase transitionGO:00447721620.053
regulation of cellular ketone metabolic processGO:0010565500.053
chromatin assembly or disassemblyGO:0006333780.052
mitotic cell cycle checkpointGO:0007093680.051
cell cycle phase transitionGO:00447701730.050
regulation of mitotic cell cycleGO:00073461890.049
nucleoside triphosphate catabolic processGO:00091433940.046
nuclear transportGO:00511691790.046
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.045
cofactor metabolic processGO:0051186870.045
response to transforming growth factor betaGO:0071559940.044
mitotic cell cycleGO:00002783260.044
negative regulation of cell cycleGO:00457861930.044
viral processGO:00160321460.044
intracellular protein transportGO:00068862700.043
regulation of cell cycle processGO:00105642660.043
defense responseGO:00069523150.042
nucleoside catabolic processGO:00091644080.042
cellular ketone metabolic processGO:0042180800.042
mitotic cell cycle processGO:19030472860.042
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.042
amine metabolic processGO:0009308440.042
regulation of mitotic cell cycle phase transitionGO:19019901180.041
cellular response to endogenous stimulusGO:00714953360.041
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.041
regulation of proteasomal protein catabolic processGO:0061136870.040
negative regulation of mitotic cell cycle phase transitionGO:1901991850.040
determination of adult lifespanGO:000834020.039
macromolecule methylationGO:0043414970.039
cellular response to uvGO:0034644320.039
negative regulation of cellular component organizationGO:00511292350.037
cellular component disassemblyGO:0022411920.037
purine ribonucleotide catabolic processGO:00091544040.037
dna integrity checkpointGO:0031570710.036
covalent chromatin modificationGO:00165692540.035
cellular response to radiationGO:0071478650.035
cellular response to growth factor stimulusGO:00713631970.035
regulation of protein catabolic processGO:00421761550.034
protein alkylationGO:0008213740.034
histone modificationGO:00165702510.033
mrna processingGO:00063971330.033
enzyme linked receptor protein signaling pathwayGO:00071673030.033
multicellular organismal agingGO:001025930.033
symbiosis encompassing mutualism through parasitismGO:00444031560.033
dna catabolic processGO:0006308490.033
small molecule biosynthetic processGO:00442831570.033
nucleoside triphosphate metabolic processGO:00091414220.033
cellular amino acid metabolic processGO:00065201160.032
regulation of intracellular transportGO:00323861950.032
response to external biotic stimulusGO:00432072610.032
protein k48 linked ubiquitinationGO:0070936380.032
response to drugGO:0042493810.031
g2 dna damage checkpointGO:0031572260.031
regulation of multi organism processGO:00439001570.030
nucleotide catabolic processGO:00091664080.030
purine ribonucleoside monophosphate catabolic processGO:00091691580.029
methylationGO:00322591060.029
negative regulation of apoptotic processGO:00430663160.029
ribonucleoside monophosphate metabolic processGO:00091611870.029
isoprenoid metabolic processGO:0006720390.028
lipid metabolic processGO:00066293810.028
cellular amine metabolic processGO:0044106410.028
positive regulation of catabolic processGO:00098963100.028
negative regulation of programmed cell deathGO:00430693210.028
carboxylic acid biosynthetic processGO:0046394970.028
positive regulation of proteolysisGO:00458621420.028
negative regulation of cell cycle phase transitionGO:1901988890.027
fatty acid metabolic processGO:00066311150.027
transforming growth factor beta receptor signaling pathwayGO:0007179760.027
regulation of defense responseGO:00313471540.027
endocytosisGO:00068971590.026
regulation of protein localizationGO:00328802960.026
nitrogen compound transportGO:00717051910.026
digestive tract developmentGO:0048565750.026
organic acid biosynthetic processGO:0016053970.026
lipid biosynthetic processGO:00086101770.026
purine nucleoside triphosphate catabolic processGO:00091463920.025
transmembrane transportGO:00550853990.025
viral life cycleGO:00190581320.025
regulation of cytoplasmic transportGO:19036491490.025
cytoplasmic transportGO:00164823790.025
dna recombinationGO:0006310770.024
generation of neuronsGO:00486991520.024
regulation of nucleocytoplasmic transportGO:0046822980.024
steroid biosynthetic processGO:0006694460.024
positive regulation of transportGO:00510503360.024
coenzyme metabolic processGO:0006732650.024
atp catabolic processGO:00062001570.024
microtubule based processGO:00070172100.024
mitotic nuclear divisionGO:00070671190.023
cellular response to light stimulusGO:0071482340.023
single organism cellular localizationGO:19025803320.023
mitotic dna damage checkpointGO:0044773280.023
positive regulation of cytoplasmic transportGO:1903651820.023
chromatin modificationGO:00165682980.022
dna catabolic process endonucleolyticGO:0000737370.022
cell divisionGO:00513011680.022
immune responseGO:00069553070.022
locomotory behaviorGO:000762610.022
innate immune responseGO:00450871780.022
nucleobase containing compound transportGO:0015931510.022
response to other organismGO:00517072610.022
dephosphorylationGO:00163112090.022
regulation of cellular amine metabolic processGO:0033238110.022
negative regulation of protein metabolic processGO:00512483910.022
response to biotic stimulusGO:00096072760.022
negative regulation of cell cycle processGO:00109481210.021
regulation of cell growthGO:00015581350.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
cellular macromolecular complex assemblyGO:00346223240.021
positive regulation of cellular catabolic processGO:00313312840.021
multi organism cellular processGO:00447641560.021
regulation of cytoskeleton organizationGO:00514931770.021
chemical homeostasisGO:00488783060.021
cation transmembrane transportGO:00986552380.021
cellular potassium ion transportGO:0071804600.021
regulation of meiotic cell cycleGO:005144540.021
maintenance of locationGO:00512351120.021
protein k29 linked ubiquitinationGO:003551940.020
regulation of protein transportGO:00512232130.020
ras protein signal transductionGO:0007265730.020
double strand break repairGO:00063021010.020
negative regulation of alpha beta t cell activationGO:004663630.020
carbohydrate derivative biosynthetic processGO:19011372070.020
regulation of cellular response to growth factor stimulusGO:0090287760.020
purine ribonucleoside catabolic processGO:00461303980.020
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.019
regulation of response to external stimulusGO:00321012220.019
atp metabolic processGO:00460341760.019
segmentationGO:003528240.019
neuromuscular junction developmentGO:000752830.019
regulation of cellular protein catabolic processGO:1903362960.019
regulation of dna metabolic processGO:00510521530.019
negative regulation of catalytic activityGO:00430863350.019
negative regulation of cell deathGO:00605483450.019
regulation of phosphatidylinositol 3 kinase signalingGO:0014066350.019
negative regulation of cellular protein metabolic processGO:00322693530.019
nervous system developmentGO:00073992930.019
ncrna processingGO:0034470830.019
regulation of establishment of protein localizationGO:00702012420.019
purine ribonucleoside metabolic processGO:00461284370.019
negative regulation of developmental processGO:00510932470.018
nucleocytoplasmic transportGO:00069131760.018
ribonucleoside catabolic processGO:00424544060.018
negative regulation of defense responseGO:0031348470.018
phosphatidylinositol mediated signalingGO:0048015550.018
sodium ion transmembrane transportGO:0035725590.018
response to growth factorGO:00708482050.018
cell projection organizationGO:00300302520.018
negative regulation of response to external stimulusGO:0032102830.018
protein targetingGO:00066051870.018
cellular lipid metabolic processGO:00442553030.018
chromosome segregationGO:00070591140.018
regulation of protein kinase activityGO:00458592890.018
positive regulation of programmed cell deathGO:00430682490.018
neuron projection developmentGO:00311751060.017
positive regulation of cellular component organizationGO:00511303760.017
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.017
negative regulation of mitotic cell cycleGO:00459301020.017
receptor mediated endocytosisGO:0006898840.017
metal ion transportGO:00300012720.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
potassium ion transmembrane transportGO:0071805600.017
regulation of cofactor metabolic processGO:005119330.017
cellular response to transforming growth factor beta stimulusGO:0071560940.017
spermatid differentiationGO:004851540.017
spindle organizationGO:0007051530.017
ribonucleoprotein complex biogenesisGO:00226131160.016
response to inorganic substanceGO:00100351270.016
negative regulation of multi organism processGO:0043901920.016
organic hydroxy compound biosynthetic processGO:1901617710.016
regulation of secretionGO:00510461940.016
cell fate determinationGO:000170930.016
inositol lipid mediated signalingGO:0048017550.016
nuclear divisionGO:00002801280.016
positive regulation of mapk cascadeGO:00434101900.016
ribonucleotide catabolic processGO:00092614050.016
mapk cascadeGO:00001652880.016
ion homeostasisGO:00508012300.016
defense response to other organismGO:00985421290.016
apoptotic signaling pathwayGO:00971902680.015
monocarboxylic acid biosynthetic processGO:0072330670.015
response to virusGO:00096151260.015
regulation of actin filament based processGO:00329701410.015
embryonic morphogenesisGO:0048598850.015
monovalent inorganic cation transportGO:00156721280.015
digestive tract morphogenesisGO:0048546560.015
receptor internalizationGO:0031623430.015
ion transmembrane transportGO:00342203380.015
regulation of transmembrane transportGO:00347621390.015
oogenesisGO:004847720.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
regulation of actin cytoskeleton organizationGO:00329561160.015
tube developmentGO:00352951250.015
establishment of protein localization to organelleGO:00725941720.015
negative regulation of organelle organizationGO:00106391260.015
organophosphate catabolic processGO:00464344300.015
epidermis developmentGO:0008544590.015
negative regulation of phosphorylationGO:00423261740.015
regulation of kinase activityGO:00435493140.015
inorganic ion transmembrane transportGO:00986602310.014
purine nucleoside triphosphate metabolic processGO:00091444120.014
coenzyme biosynthetic processGO:0009108240.014
hindbrain developmentGO:003090230.014
regulation of transmembrane transporter activityGO:0022898740.014
immune effector processGO:00022521590.014
regulation of mapk cascadeGO:00434082620.014
regulation of vesicle mediated transportGO:00606271300.014
secretion by cellGO:00329402260.014
protein localization to organelleGO:00333652800.014
positive regulation of intracellular transportGO:00323881040.014
negative regulation of immune system processGO:00026831360.014
myeloid cell differentiationGO:00300991170.014
positive regulation of immune responseGO:00507781590.014
cell growthGO:00160491600.014
cofactor biosynthetic processGO:0051188310.014
regulation of lipid metabolic processGO:0019216960.014
organelle fissionGO:00482851490.014
regulation of transporter activityGO:0032409820.014
dna conformation changeGO:00711031130.014
mitotic dna integrity checkpointGO:0044774300.014
regulation of cell differentiationGO:00455953930.014
regulation of viral processGO:00507921030.013
negative regulation of cell proliferationGO:00082852280.013
organic hydroxy compound metabolic processGO:19016151470.013
female gamete generationGO:000729220.013
regulation of transferase activityGO:00513383550.013
immune system developmentGO:00025201950.013
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.013
potassium ion transportGO:0006813620.013
positive regulation of organelle organizationGO:00106381950.013
peptidyl tyrosine phosphorylationGO:00181081700.013
small gtpase mediated signal transductionGO:0007264780.013
negative regulation of transportGO:00510511760.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of cellular component movementGO:00512703340.013
monocarboxylic acid metabolic processGO:00327871850.013
regulation of ketone biosynthetic processGO:001056670.013
interaction with hostGO:0051701420.013
protein maturationGO:00516042330.013
glycoprotein metabolic processGO:00091001100.013
oxidoreduction coenzyme metabolic processGO:0006733190.013
negative regulation of multicellular organismal processGO:00512413170.013
signal transduction by phosphorylationGO:00230142970.013
secretionGO:00469032540.013
protein processingGO:00164852260.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.013
positive regulation of hydrolase activityGO:00513453310.013
regulation of cellular component biogenesisGO:00440872810.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
rna export from nucleusGO:0006405330.013
alcohol biosynthetic processGO:0046165520.012
purine ribonucleoside triphosphate metabolic processGO:00092054110.012
positive regulation of cell deathGO:00109422630.012
inorganic cation transmembrane transportGO:00986621940.012
rna localizationGO:0006403410.012
regulation of protein localization to cell surfaceGO:2000008150.012
receptor metabolic processGO:0043112810.012
cation transportGO:00068123310.012
guanosine containing compound metabolic processGO:19010682440.012
positive regulation of nucleocytoplasmic transportGO:0046824540.012
negative regulation of protein transportGO:0051224750.012
peptidyl tyrosine modificationGO:00182121700.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.012
cell developmentGO:00484683280.012
positive regulation of proteasomal protein catabolic processGO:1901800350.012
regulation of ion transportGO:00432691890.012
regulation of cellular amino acid metabolic processGO:000652160.012
cell morphogenesisGO:00009022960.012
positive regulation of protein catabolic processGO:0045732750.012
negative regulation of cellular amine metabolic processGO:003323930.012
negative regulation of sodium ion transportGO:001076630.012
ubiquitin dependent smad protein catabolic processGO:003057940.012
negative regulation of sodium ion transmembrane transportGO:190230620.012
lipid localizationGO:00108761060.012
response to cytokineGO:00340972320.012
ribonucleoside triphosphate metabolic processGO:00091994120.012
tube morphogenesisGO:0035239950.012
cellular protein complex assemblyGO:00436231880.012
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.011
regulation of immune responseGO:00507762010.011
intracellular steroid hormone receptor signaling pathwayGO:0030518610.011
organonitrogen compound biosynthetic processGO:19015662000.011
ribosomal subunit export from nucleusGO:000005440.011
regulation of synaptic plasticityGO:004816730.011
negative regulation of cell differentiationGO:00455961710.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
cellular response to oxidative stressGO:0034599850.011
regenerationGO:003109940.011
intracellular receptor signaling pathwayGO:00305221040.011
negative regulation of phosphorus metabolic processGO:00105632670.011
double strand break repair via homologous recombinationGO:0000724500.011
regulation of homeostatic processGO:00328441210.011
nuclear exportGO:0051168690.011
response to metal ionGO:0010038840.011
late endosome to vacuole transportGO:004532420.011
regulation of protein maturationGO:19033171500.011
negative regulation of protein modification processGO:00314002000.011
fatty acid biosynthetic processGO:0006633460.011
cellular component morphogenesisGO:00329893140.011
meiotic chromosome segregationGO:004513240.011
negative regulation of immune effector processGO:0002698380.011
regulation of membrane potentialGO:0042391950.011
regulation of endocytosisGO:0030100720.011
negative regulation of transferase activityGO:00513481240.011
sodium ion transportGO:0006814610.011
endosome transport via multivesicular body sorting pathwayGO:003250930.011
cellular response to cytokine stimulusGO:00713451810.011
regulation of chromosome organizationGO:00330441030.011
positive regulation of immune system processGO:00026842830.011
negative regulation of myeloid cell differentiationGO:0045638420.011
regulation of lipid biosynthetic processGO:0046890470.011
positive regulation of nucleotide metabolic processGO:00459812300.011
phosphatidylinositol 3 kinase signalingGO:0014065480.011
viral genome replicationGO:0019079500.010
alcohol metabolic processGO:00060661140.010
positive regulation of kinase activityGO:00336742040.010
anatomical structure formation involved in morphogenesisGO:00486462840.010
mrna export from nucleusGO:0006406290.010
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068280.010
regulation of growthGO:00400081650.010
ncrna metabolic processGO:00346601080.010
response to organic cyclic compoundGO:00140702040.010
positive regulation of multi organism processGO:0043902560.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
neuron developmentGO:00486661130.010
lymphocyte activationGO:00466491330.010
photoreceptor cell differentiationGO:004653020.010
ribonucleoprotein complex export from nucleusGO:007142640.010
regulation of anatomical structure sizeGO:00900661010.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:0043162100.010
regulation of mrna export from nucleusGO:001079330.010
nucleosome organizationGO:0034728660.010
epithelium developmentGO:00604292270.010
nucleoside phosphate catabolic processGO:19012924120.010
negative regulation of protein processingGO:00109551420.010
dolichol biosynthetic processGO:001940810.010
adult locomotory behaviorGO:000834410.010

ERCC6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
xeroderma pigmentosumDOID:005042780.027
nervous system diseaseDOID:8634310.026
central nervous system diseaseDOID:3311860.026
sensory system diseaseDOID:00501552030.025
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
retinal diseaseDOID:56791180.017
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
neurodegenerative diseaseDOID:12891020.017
disease of metabolismDOID:00146672950.012
organ system cancerDOID:00506861640.011
retinal degenerationDOID:8466890.005
macular degenerationDOID:4448200.001
respiratory system cancerDOID:0050615160.001
lung cancerDOID:1324160.001
degeneration of macula and posterior poleDOID:2007170.001
age related macular degenerationDOID:10871170.001