Homo sapiens

51 known processes

PFKL

phosphofructokinase, liver

(Aliases: FLJ30173,FLJ40909,DKFZp686L2097,DKFZp686G1648,PFK-B)

PFKL biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate metabolic processGO:00059752070.829
monocarboxylic acid metabolic processGO:00327871850.539
lipid biosynthetic processGO:00086101770.387
single organism carbohydrate metabolic processGO:00447231930.294
generation of precursor metabolites and energyGO:0006091680.279
cellular homeostasisGO:00197251960.246
single organism carbohydrate catabolic processGO:0044724330.237
carbohydrate catabolic processGO:0016052360.161
peptidyl tyrosine phosphorylationGO:00181081700.139
lipid metabolic processGO:00066293810.129
regulation of cell cycleGO:00517263930.123
positive regulation of cellular amino acid metabolic processGO:004576430.112
response to abiotic stimulusGO:00096283360.108
muscle cell cellular homeostasisGO:004671630.102
microtubule based processGO:00070172100.098
cellular lipid metabolic processGO:00442553030.097
positive regulation of cellular amine metabolic processGO:003324070.093
mitotic cell cycleGO:00002783260.092
positive regulation of cellular component organizationGO:00511303760.091
determination of adult lifespanGO:000834020.087
signal transduction by phosphorylationGO:00230142970.079
negative regulation of cellular protein metabolic processGO:00322693530.075
regulation of map kinase activityGO:00434051080.072
canonical wnt signaling pathwayGO:00600701160.071
regulation of cell cycle processGO:00105642660.070
mitotic cell cycle phase transitionGO:00447721620.064
cellular carbohydrate metabolic processGO:0044262840.063
regulation of cytokine productionGO:00018172320.061
cellular response to dna damage stimulusGO:00069743790.061
organic acid biosynthetic processGO:0016053970.060
positive regulation of protein phosphorylationGO:00019343130.060
cytokine productionGO:00018162470.059
peptidyl tyrosine modificationGO:00182121700.059
cell cycle phase transitionGO:00447701730.059
mitotic cell cycle processGO:19030472860.058
regulation of mitotic cell cycleGO:00073461890.057
peptidyl serine phosphorylationGO:00181051010.056
negative regulation of protein metabolic processGO:00512483910.055
cellular response to external stimulusGO:00714961110.054
regulation of cytoskeleton organizationGO:00514931770.054
actin cytoskeleton organizationGO:00300362070.053
cellular ketone metabolic processGO:0042180800.051
cellular protein complex assemblyGO:00436231880.051
positive regulation of developmental processGO:00510943140.048
glycerolipid biosynthetic processGO:0045017510.048
organonitrogen compound biosynthetic processGO:19015662000.047
cellular macromolecular complex assemblyGO:00346223240.045
purine ribonucleoside monophosphate metabolic processGO:00091671860.045
ribonucleoside monophosphate metabolic processGO:00091611870.044
positive regulation of mapk cascadeGO:00434101900.044
regulation of protein serine threonine kinase activityGO:00719001790.044
regulation of mapk cascadeGO:00434082620.041
positive regulation of apoptotic processGO:00430652460.041
cellular amine metabolic processGO:0044106410.040
organophosphate biosynthetic processGO:00904071630.039
organelle fissionGO:00482851490.039
glycerolipid metabolic processGO:00464861070.038
regulation of kinase activityGO:00435493140.038
amine metabolic processGO:0009308440.038
regulation of transferase activityGO:00513383550.037
neuron differentiationGO:00301821380.036
negative regulation of catalytic activityGO:00430863350.036
muscle contractionGO:0006936730.035
regulation of cellular amine metabolic processGO:0033238110.035
heart developmentGO:0007507950.035
intrinsic apoptotic signaling pathwayGO:00971931270.035
embryo developmentGO:00097901230.034
cellular response to cytokine stimulusGO:00713451810.034
chemical homeostasisGO:00488783060.033
dna integrity checkpointGO:0031570710.032
actin filament organizationGO:00070151280.031
response to cytokineGO:00340972320.030
neurogenesisGO:00220081690.029
epithelium developmentGO:00604292270.029
cellular amino acid metabolic processGO:00065201160.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.027
generation of neuronsGO:00486991520.027
regulation of cellular ketone metabolic processGO:0010565500.027
multicellular organismal agingGO:001025930.027
cardiovascular system developmentGO:00723582620.027
regulation of nervous system developmentGO:0051960880.027
response to oxidative stressGO:00069791210.027
carbohydrate derivative biosynthetic processGO:19011372070.026
positive regulation of cell proliferationGO:00082843010.026
purine nucleoside monophosphate catabolic processGO:00091281580.026
oxidation reduction processGO:00551143960.025
regulation of cellular amino acid metabolic processGO:000652160.025
regulation of cellular response to stressGO:00801352440.025
organic hydroxy compound metabolic processGO:19016151470.025
monosaccharide metabolic processGO:0005996740.024
post embryonic developmentGO:000979120.024
modification dependent protein catabolic processGO:00199412090.024
negative regulation of developmental processGO:00510932470.024
regulation of proteolysisGO:00301622930.024
cellular response to abiotic stimulusGO:00712141170.024
cofactor metabolic processGO:0051186870.023
neuroblast proliferationGO:000740540.023
positive regulation of cytokine productionGO:00018191670.023
response to decreased oxygen levelsGO:0036293960.023
epidermis developmentGO:0008544590.022
regulation of establishment of protein localizationGO:00702012420.022
response to external biotic stimulusGO:00432072610.022
response to mechanical stimulusGO:0009612510.022
vesicle mediated transportGO:00161923710.021
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.021
mapk cascadeGO:00001652880.021
system processGO:00030083490.021
positive regulation of erk1 and erk2 cascadeGO:0070374750.021
glycolytic processGO:0006096170.021
negative regulation of mitotic cell cycleGO:00459301020.020
negative regulation of protein modification processGO:00314002000.020
skin developmentGO:0043588760.020
regulation of peptidyl tyrosine phosphorylationGO:00507301080.020
apoptotic signaling pathwayGO:00971902680.020
negative regulation of protein phosphorylationGO:00019331400.020
activation of protein kinase activityGO:0032147900.020
cell projection organizationGO:00300302520.020
posttranscriptional regulation of gene expressionGO:00106082130.020
actin filament based processGO:00300292240.020
female gamete generationGO:000729220.019
cell morphogenesisGO:00009022960.019
nervous system developmentGO:00073992930.019
pyruvate metabolic processGO:0006090260.019
negative regulation of phosphorylationGO:00423261740.019
regulation of cellular component biogenesisGO:00440872810.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
regulation of protein kinase activityGO:00458592890.019
fatty acid derivative biosynthetic processGO:1901570180.018
single organism cellular localizationGO:19025803320.018
protein homooligomerizationGO:00512601000.018
taxisGO:00423301570.018
positive regulation of cellular component biogenesisGO:00440891580.018
regulation of cell differentiationGO:00455953930.018
negative regulation of cell deathGO:00605483450.018
circulatory system developmentGO:00723592620.018
positive regulation of phosphorylationGO:00423273940.018
somatic muscle developmentGO:000752510.018
phosphatidic acid biosynthetic processGO:000665440.018
polysaccharide biosynthetic processGO:0000271270.017
glycerophospholipid metabolic processGO:0006650840.017
attachment of gpi anchor to proteinGO:001625510.017
negative regulation of phosphorus metabolic processGO:00105632670.017
regulation of canonical wnt signaling pathwayGO:0060828880.017
positive regulation of transferase activityGO:00513472270.017
carboxylic acid biosynthetic processGO:0046394970.017
negative regulation of intracellular signal transductionGO:19025321830.017
secretion by cellGO:00329402260.017
Mouse
nucleotide catabolic processGO:00091664080.017
hexose metabolic processGO:0019318550.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of cell morphogenesisGO:00226041530.016
response to hypoxiaGO:0001666960.016
mitotic nuclear divisionGO:00070671190.016
cellular component morphogenesisGO:00329893140.016
mitochondrion organizationGO:00070051560.016
cellular protein catabolic processGO:00442572610.016
cell activationGO:00017752130.015
ribonucleotide catabolic processGO:00092614050.015
carboxylic acid catabolic processGO:0046395710.015
neurological system processGO:00508771630.015
positive regulation of protein kinase activityGO:00458601900.015
somitogenesisGO:000175620.015
fatty acid metabolic processGO:00066311150.015
nucleoside monophosphate catabolic processGO:00091251590.015
organelle assemblyGO:00709251760.015
carboxylic acid transportGO:0046942630.015
cellular macromolecule catabolic processGO:00442653800.015
immune responseGO:00069553070.015
nuclear divisionGO:00002801280.014
regulation of cellular component movementGO:00512703340.014
peptidyl serine modificationGO:00182091060.014
regulation of wnt signaling pathwayGO:00301111230.014
behavioral response to ethanolGO:004814920.014
regulation of bindingGO:00510981110.014
biological adhesionGO:00226103310.014
negative regulation of cellular component organizationGO:00511292350.014
glycogen metabolic processGO:0005977220.014
response to oxygen containing compoundGO:19017003690.014
response to other organismGO:00517072610.014
response to mercury ionGO:004668940.014
organic hydroxy compound transportGO:0015850630.014
neuron projection developmentGO:00311751060.014
purine ribonucleotide catabolic processGO:00091544040.014
glycerophospholipid biosynthetic processGO:0046474400.014
chemotaxisGO:00069351570.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
microtubule cytoskeleton organizationGO:00002261760.013
regulation of body fluid levelsGO:0050878990.013
hormone transportGO:0009914680.013
Mouse
positive regulation of map kinase activityGO:0043406800.013
response to molecule of bacterial originGO:0002237820.013
regulation of response to external stimulusGO:00321012220.013
response to inorganic substanceGO:00100351270.013
carbohydrate phosphorylationGO:0046835170.013
positive regulation of cell deathGO:00109422630.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
regulation of hormone levelsGO:00108171250.013
Mouse
positive regulation of cell differentiationGO:00455972110.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of ion transmembrane transportGO:00347651320.013
purine ribonucleoside triphosphate metabolic processGO:00092054110.013
reproductive processGO:00224141060.012
ribonucleoside catabolic processGO:00424544060.012
small molecule biosynthetic processGO:00442831570.012
neuron developmentGO:00486661130.012
positive regulation of transportGO:00510503360.012
alcohol metabolic processGO:00060661140.012
regulation of locomotionGO:00400123290.012
negative regulation of apoptotic processGO:00430663160.012
regenerationGO:003109940.012
nucleoside monophosphate metabolic processGO:00091231910.012
negative regulation of canonical wnt signaling pathwayGO:0090090550.012
regulation of protein transportGO:00512232130.012
cell adhesionGO:00071553250.012
cellular chemical homeostasisGO:00550821800.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
negative regulation of programmed cell deathGO:00430693210.012
regulation of neural precursor cell proliferationGO:200017740.012
dephosphorylationGO:00163112090.012
regulation of cell cycle phase transitionGO:19019871260.012
oxidoreduction coenzyme metabolic processGO:0006733190.011
positive regulation of neuron differentiationGO:0045666400.011
intracellular protein transportGO:00068862700.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
negative regulation of protein maturationGO:19033181420.011
atp metabolic processGO:00460341760.011
wound healingGO:00420601150.011
negative regulation of transferase activityGO:00513481240.011
mitochondrial transportGO:0006839600.011
muscle system processGO:0003012810.011
protein modification by small protein conjugationGO:00324463420.011
ubiquitin dependent protein catabolic processGO:00065112060.011
growthGO:00400072020.011
glycoprotein biosynthetic processGO:0009101910.011
protein glycosylationGO:0006486620.011
protein processingGO:00164852260.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
defense responseGO:00069523150.011
positive regulation of immune system processGO:00026842830.011
response to growth factorGO:00708482050.011
protein autophosphorylationGO:00467771230.011
regulation of protein maturationGO:19033171500.011
protein oligomerizationGO:00512591730.011
cell divisionGO:00513011680.011
regulation of anatomical structure sizeGO:00900661010.011
regulation of mitosisGO:0007088630.011
positive regulation of kinase activityGO:00336742040.011
behaviorGO:00076101120.011
guanosine containing compound catabolic processGO:19010692390.010
immune response regulating signaling pathwayGO:0002764970.010
carbohydrate biosynthetic processGO:0016051420.010
ribonucleotide biosynthetic processGO:0009260810.010
regulation of protein complex assemblyGO:00432541470.010
regulation of erk1 and erk2 cascadeGO:0070372990.010
oogenesisGO:004847720.010
response to biotic stimulusGO:00096072760.010
polysaccharide metabolic processGO:0005976330.010
purine nucleotide catabolic processGO:00061954050.010
phospholipid biosynthetic processGO:0008654440.010
aminoglycan metabolic processGO:0006022390.010
regulation of cell shapeGO:0008360480.010
steroid biosynthetic processGO:0006694460.010
protein targetingGO:00066051870.010

PFKL disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.064
carbohydrate metabolic disorderDOID:2978550.064
disease of metabolismDOID:00146672950.064
glycogen storage diseaseDOID:2747100.060
glycogen metabolism disorderDOID:0050728100.060
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
musculoskeletal system diseaseDOID:172230.016
neonatal period electroclinical syndromeDOID:0050702190.014
electroclinical syndromeDOID:0050701320.014
epilepsy syndromeDOID:1826410.014
brain diseaseDOID:936730.014
immune system diseaseDOID:29141550.013