Homo sapiens

118 known processes

CASP8AP2

caspase 8 associated protein 2

(Aliases: KIAA1315,FLASH,FLJ11208,CED-4,RIP25)

CASP8AP2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743790.892
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.638
post embryonic developmentGO:000979120.609
regulation of cellular amine metabolic processGO:0033238110.468
positive regulation of cellular amine metabolic processGO:003324070.403
mitotic cell cycle processGO:19030472860.384
positive regulation of proteolysisGO:00458621420.373
regulation of cellular amino acid metabolic processGO:000652160.373
cellular amino acid metabolic processGO:00065201160.340
hemopoiesisGO:00300971800.335
regulation of proteolysisGO:00301622930.289
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.289
negative regulation of apoptotic processGO:00430663160.267
amine metabolic processGO:0009308440.254
hematopoietic or lymphoid organ developmentGO:00485341860.247
regulation of cellular ketone metabolic processGO:0010565500.235
negative regulation of cell cycle phase transitionGO:1901988890.222
negative regulation of cell deathGO:00605483450.218
anatomical structure formation involved in morphogenesisGO:00486462840.216
cellular ketone metabolic processGO:0042180800.205
positive regulation of hydrolase activityGO:00513453310.194
regulation of apoptotic signaling pathwayGO:20012331750.194
cellular macromolecule catabolic processGO:00442653800.178
cellular amine metabolic processGO:0044106410.163
response to abiotic stimulusGO:00096283360.152
apoptotic signaling pathwayGO:00971902680.147
response to oxygen containing compoundGO:19017003690.145
maintenance of locationGO:00512351120.136
mitotic cell cycleGO:00002783260.135
positive regulation of cellular amino acid metabolic processGO:004576430.133
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.133
mitotic dna integrity checkpointGO:0044774300.132
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.132
ameboidal type cell migrationGO:00016671350.129
regulation of endopeptidase activityGO:00525481700.129
negative regulation of mitotic cell cycleGO:00459301020.121
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.119
regulation of cellular response to stressGO:00801352440.118
regulation of intracellular transportGO:00323861950.108
microtubule based processGO:00070172100.107
negative regulation of protein metabolic processGO:00512483910.105
nuclear divisionGO:00002801280.104
proteolysis involved in cellular protein catabolic processGO:00516032440.103
regulation of protein processingGO:00706131500.100
cellular response to abiotic stimulusGO:00712141170.096
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.095
pharynx developmentGO:006046510.093
trail activated apoptotic signaling pathwayGO:003646240.092
negative regulation of proteolysisGO:00458611320.091
embryo developmentGO:00097901230.090
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.090
blastocyst developmentGO:000182430.090
negative regulation of cell cycleGO:00457861930.089
regulation of proteasomal protein catabolic processGO:0061136870.089
positive regulation of cell deathGO:00109422630.085
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.085
mitotic dna damage checkpointGO:0044773280.084
vasculature developmentGO:00019441810.084
regulation of cell motilityGO:20001452990.084
negative regulation of catalytic activityGO:00430863350.081
cellular protein catabolic processGO:00442572610.079
protein modification by small protein conjugationGO:00324463420.074
embryonic epithelial tube formationGO:000183840.073
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.072
modification dependent protein catabolic processGO:00199412090.072
positive regulation of cellular component organizationGO:00511303760.071
protein catabolic processGO:00301633250.070
regulation of cell cycle processGO:00105642660.069
cell cycle phase transitionGO:00447701730.068
double strand break repairGO:00063021010.068
endothelial cell migrationGO:0043542860.068
regulation of angiogenesisGO:0045765920.068
blood vessel developmentGO:00015681720.067
regulation of cell cycleGO:00517263930.067
regulation of leukocyte differentiationGO:1902105610.066
regulation of cellular protein catabolic processGO:1903362960.064
regulation of anatomical structure morphogenesisGO:00226032860.063
sex differentiationGO:0007548450.062
proteasomal protein catabolic processGO:00104981760.061
epithelial cell migrationGO:00106311190.061
regulation of intracellular protein transportGO:00331571230.058
chromosome segregationGO:00070591140.057
response to cytokineGO:00340972320.056
negative regulation of cellular protein metabolic processGO:00322693530.055
response to organic cyclic compoundGO:00140702040.055
positive regulation of phosphorylationGO:00423273940.055
regulation of mitotic cell cycle phase transitionGO:19019901180.055
regulation of protein modification by small protein conjugation or removalGO:19033201070.054
response to organonitrogen compoundGO:00102431560.054
leukocyte differentiationGO:0002521980.053
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.052
positive regulation of apoptotic signaling pathwayGO:2001235700.051
mitotic sister chromatid segregationGO:0000070530.051
ribonucleotide catabolic processGO:00092614050.051
cell fate determinationGO:000170930.051
extrinsic apoptotic signaling pathwayGO:00971911190.050
mitotic nuclear divisionGO:00070671190.050
i kappab kinase nf kappab signalingGO:00072491660.049
regulation of sequence specific dna binding transcription factor activityGO:00510902110.048
microtubule cytoskeleton organizationGO:00002261760.048
negative regulation of mitotic cell cycle phase transitionGO:1901991850.048
response to other organismGO:00517072610.048
protein maturationGO:00516042330.048
dna damage checkpointGO:0000077680.047
regulation of protein localizationGO:00328802960.047
negative regulation of transferase activityGO:00513481240.047
positive regulation of protein sumoylationGO:003323570.047
positive regulation of protein phosphorylationGO:00019343130.046
regulation of myeloid cell differentiationGO:0045637810.046
positive regulation of cellular protein catabolic processGO:1903364370.046
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.046
response to biotic stimulusGO:00096072760.045
organelle assemblyGO:00709251760.045
enzyme linked receptor protein signaling pathwayGO:00071673030.044
cellular response to radiationGO:0071478650.044
positive regulation of cysteine type endopeptidase activityGO:2001056790.044
signal transduction by p53 class mediatorGO:0072331720.043
nuclear exportGO:0051168690.043
cell type specific apoptotic processGO:00972851250.043
positive regulation of transportGO:00510503360.043
response to radiationGO:00093141510.042
positive regulation of cell proliferationGO:00082843010.042
nucleoside monophosphate metabolic processGO:00091231910.042
regulation of nucleocytoplasmic transportGO:0046822980.042
regulation of cysteine type endopeptidase activityGO:20001161270.041
cell divisionGO:00513011680.040
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.040
nucleoside phosphate catabolic processGO:19012924120.040
response to mechanical stimulusGO:0009612510.039
ribonucleoside triphosphate catabolic processGO:00092033910.039
tube developmentGO:00352951250.039
blood vessel morphogenesisGO:00485141620.038
signal transduction in response to dna damageGO:0042770570.038
histone modificationGO:00165702510.038
negative regulation of protein modification processGO:00314002000.038
protein export from nucleusGO:0006611290.038
morphogenesis of embryonic epitheliumGO:001633140.038
negative regulation of cytoplasmic transportGO:1903650460.038
tissue migrationGO:00901301190.037
cellular response to oxygen containing compoundGO:19017012760.037
positive regulation of immune system processGO:00026842830.037
female gamete generationGO:000729220.037
response to hormoneGO:00097251750.037
cellular protein complex assemblyGO:00436231880.037
purine ribonucleoside metabolic processGO:00461284370.037
response to tumor necrosis factorGO:0034612760.036
protein homooligomerizationGO:00512601000.036
regulation of establishment of protein localizationGO:00702012420.036
embryo development ending in birth or egg hatchingGO:0009792340.035
nervous system developmentGO:00073992930.035
microtubule organizing center organizationGO:0031023620.035
meiosis iGO:000712740.035
purine nucleoside monophosphate catabolic processGO:00091281580.034
regulation of protein transportGO:00512232130.033
ubiquitin dependent protein catabolic processGO:00065112060.033
protein localization to organelleGO:00333652800.033
positive regulation of developmental processGO:00510943140.033
positive regulation of cell differentiationGO:00455972110.033
regulation of cell cycle phase transitionGO:19019871260.032
cell cycle checkpointGO:00000751170.032
regulation of peptidase activityGO:00525471800.032
determination of adult lifespanGO:000834020.032
regulation of dna metabolic processGO:00510521530.032
regulation of locomotionGO:00400123290.032
positive regulation of organelle organizationGO:00106381950.031
negative regulation of cell cycle processGO:00109481210.031
negative regulation of programmed cell deathGO:00430693210.031
organelle fissionGO:00482851490.031
maintenance of protein location in cellGO:0032507560.031
protein oligomerizationGO:00512591730.031
dna conformation changeGO:00711031130.031
regulation of cytoplasmic transportGO:19036491490.031
regulation of i kappab kinase nf kappab signalingGO:00431221620.031
cytoplasmic transportGO:00164823790.031
protein ubiquitinationGO:00165673140.031
regulation of cell migrationGO:00303342890.030
response to nitrogen compoundGO:19016981840.030
dna repairGO:00062811980.030
cellular response to organonitrogen compoundGO:00714171240.029
regulation of transferase activityGO:00513383550.029
regulation of lymphocyte activationGO:00512491030.029
regulation of vasculature developmentGO:1901342970.029
dna damage response signal transduction by p53 class mediatorGO:0030330440.029
negative regulation of protein maturationGO:19033181420.028
regulation of cell differentiationGO:00455953930.028
positive regulation of cell cycle processGO:00900681060.027
centrosome organizationGO:0051297580.027
lymphocyte activationGO:00466491330.027
purine nucleoside monophosphate metabolic processGO:00091261860.027
digestive tract developmentGO:0048565750.026
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.026
mitotic cell cycle checkpointGO:0007093680.026
negative regulation of intracellular signal transductionGO:19025321830.026
regulation of response to external stimulusGO:00321012220.026
negative regulation of transportGO:00510511760.026
positive regulation of apoptotic processGO:00430652460.026
nucleocytoplasmic transportGO:00069131760.025
angiogenesisGO:00015251470.025
circulatory system developmentGO:00723592620.025
organophosphate catabolic processGO:00464344300.025
intracellular protein transportGO:00068862700.025
defense response to other organismGO:00985421290.025
response to external biotic stimulusGO:00432072610.024
intrinsic apoptotic signaling pathwayGO:00971931270.024
epithelium migrationGO:00901321190.024
purine containing compound catabolic processGO:00725234110.024
response to acid chemicalGO:0001101660.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
cardiovascular system developmentGO:00723582620.023
chromatin modificationGO:00165682980.023
protein import into nucleusGO:00066061040.023
head developmentGO:00603221080.022
regulation of cell divisionGO:00513021160.022
immune system developmentGO:00025201950.022
ribonucleoside catabolic processGO:00424544060.022
cell cycle g1 s phase transitionGO:0044843800.022
signal transduction by phosphorylationGO:00230142970.022
developmental process involved in reproductionGO:0003006660.022
positive regulation of catabolic processGO:00098963100.022
reproductive processGO:00224141060.021
fas signaling pathwayGO:003633730.021
protein targetingGO:00066051870.021
regulation of response to dna damage stimulusGO:2001020940.021
embryonic camera type eye morphogenesisGO:004859620.021
protein processingGO:00164852260.021
negative regulation of intracellular transportGO:0032387600.021
regulation of protein export from nucleusGO:0046825150.021
modification dependent macromolecule catabolic processGO:00436322120.020
nuclear transportGO:00511691790.020
regulation of cellular component biogenesisGO:00440872810.020
execution phase of apoptosisGO:0097194320.020
regulation of chromatin modificationGO:1903308510.020
cellular response to tumor necrosis factorGO:0071356630.020
negative regulation of multicellular organismal processGO:00512413170.020
oogenesisGO:004847720.020
purine ribonucleoside monophosphate catabolic processGO:00091691580.020
regulation of protein catabolic processGO:00421761550.020
innate immune responseGO:00450871780.020
response to interferon gammaGO:0034341390.020
protein sumoylationGO:0016925250.020
anatomical structure homeostasisGO:00602491000.020
nucleoside triphosphate catabolic processGO:00091433940.019
dna replicationGO:00062601160.019
cellular response to hormone stimulusGO:00328701250.019
telomere maintenanceGO:0000723320.019
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.019
negative regulation of phosphate metabolic processGO:00459362670.019
regulation of chromosome organizationGO:00330441030.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
positive regulation of nucleotide catabolic processGO:00308131850.018
positive regulation of cellular component movementGO:00512721810.018
centrosome cycleGO:0007098320.018
homeostasis of number of cellsGO:0048872400.018
mrna splicing via spliceosomeGO:0000398890.018
sister chromatid segregationGO:0000819540.018
positive regulation of chromatin modificationGO:1903310300.018
t cell differentiation in thymusGO:003307740.018
protein polymerizationGO:0051258710.018
single organism reproductive processGO:0044702980.017
positive regulation of chromosome organizationGO:2001252410.017
regulation of protein targetingGO:1903533910.017
spindle organizationGO:0007051530.017
reproductive system developmentGO:0061458560.017
regulation of mitotic cell cycleGO:00073461890.017
response to oxygen levelsGO:00704821000.017
cellular response to peptideGO:1901653590.017
positive regulation of intracellular protein transportGO:0090316760.017
chromatin organizationGO:00063253510.017
neural tube formationGO:000184130.017
spermatid developmentGO:000728640.017
leukocyte activationGO:00453211640.017
dna integrity checkpointGO:0031570710.017
positive regulation of cellular catabolic processGO:00313312840.017
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.017
cell activationGO:00017752130.016
regulation of epithelial cell migrationGO:0010632930.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
atp metabolic processGO:00460341760.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
nucleoside monophosphate catabolic processGO:00091251590.015
negative regulation of apoptotic signaling pathwayGO:2001234970.015
regulation of microtubule cytoskeleton organizationGO:0070507610.015
regulation of nervous system developmentGO:0051960880.015
response to cobalt ionGO:003202510.015
response to virusGO:00096151260.015
negative regulation of intracellular protein transportGO:0090317420.015
brain developmentGO:0007420970.015
negative regulation of nucleocytoplasmic transportGO:0046823370.015
cellular macromolecular complex assemblyGO:00346223240.015
cellular response to oxidative stressGO:0034599850.015
leukocyte apoptotic processGO:0071887310.015
response to lipidGO:00339932060.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
positive regulation of myeloid leukocyte differentiationGO:0002763240.015
muscle organ developmentGO:0007517560.014
response to light stimulusGO:0009416870.014
epithelium developmentGO:00604292270.014
protein targeting to nucleusGO:00447441040.014
myeloid leukocyte differentiationGO:0002573600.014
regulation of chromatin organizationGO:1902275560.014
regulation of fas signaling pathwayGO:190204420.014
dna packagingGO:0006323770.014
cell projection morphogenesisGO:00488581290.014
regulation of cytokine productionGO:00018172320.014
neural nucleus developmentGO:0048857470.014
cellular response to endogenous stimulusGO:00714953360.014
central nervous system developmentGO:00074171230.013
regulation of nucleotide metabolic processGO:00061402690.013
negative regulation of protein processingGO:00109551420.013
regulation of endothelial cell migrationGO:0010594670.013
neuron apoptotic processGO:0051402390.013
reproductionGO:0000003630.013
regulation of cell cycle arrestGO:0071156360.013
meiotic chromosome segregationGO:004513240.013
nitrogen compound transportGO:00717051910.013
purine nucleotide catabolic processGO:00061954050.013
cell developmentGO:00484683280.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.013
g1 dna damage checkpointGO:0044783180.013
positive regulation of nervous system developmentGO:0051962540.013
regulation of cellular component movementGO:00512703340.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.013
regulation of neural precursor cell proliferationGO:200017740.013
response to ionizing radiationGO:0010212650.013
purine nucleoside catabolic processGO:00061523980.012
oocyte differentiationGO:000999420.012
t cell activationGO:0042110990.012
negative regulation of dna replicationGO:0008156290.012
negative regulation of cell differentiationGO:00455961710.012
actomyosin structure organizationGO:0031032590.012
positive regulation of cell cycle arrestGO:0071158230.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
nuclear importGO:00511701060.012
positive regulation of programmed cell deathGO:00430682490.012
response to hypoxiaGO:0001666960.012
compound eye developmentGO:004874910.012
cell adhesionGO:00071553250.012
gonad developmentGO:0008406340.012
multicellular organismal agingGO:001025930.012
single organism nuclear importGO:19025931040.012
stem cell differentiationGO:0048863930.012
negative regulation of cell migrationGO:00303361020.012
positive regulation of cell migrationGO:00303351720.012
chromosome separationGO:0051304230.012
negative regulation of t cell apoptotic processGO:007023340.012
nucleoside triphosphate metabolic processGO:00091414220.011
g1 s transition of mitotic cell cycleGO:0000082780.011
nucleotide catabolic processGO:00091664080.011
response to nutrient levelsGO:0031667810.011
spindle elongationGO:005123140.011
immune responseGO:00069553070.011
glycosyl compound catabolic processGO:19016584130.011
neurogenesisGO:00220081690.011
oocyte developmentGO:004859910.011
generation of precursor metabolites and energyGO:0006091680.011
nucleoside catabolic processGO:00091644080.011
regulation of cell cycle g1 s phase transitionGO:1902806420.011
multi organism metabolic processGO:0044033410.011
positive regulation of jak stat cascadeGO:0046427350.011
vesicle mediated transportGO:00161923710.011
response to drugGO:0042493810.011
cell projection organizationGO:00300302520.011
regulation of cell developmentGO:00602841610.011
response to extracellular stimulusGO:0009991850.011
positive regulation of histone modificationGO:0031058290.011
generation of neuronsGO:00486991520.011
engulfment of apoptotic cellGO:004365220.011
purine ribonucleotide catabolic processGO:00091544040.011
locomotory behaviorGO:000762610.011
response to endoplasmic reticulum stressGO:0034976490.011
embryonic morphogenesisGO:0048598850.011
positive regulation of protein transportGO:00512221350.011
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.011
organ morphogenesisGO:00098871470.011
response to inorganic substanceGO:00100351270.010
response to metal ionGO:0010038840.010
negative regulation of response to external stimulusGO:0032102830.010
cell cycle arrestGO:0007050710.010
regulation of dna repairGO:0006282470.010
regulation of protein kinase activityGO:00458592890.010
negative regulation of protein serine threonine kinase activityGO:0071901570.010
negative regulation of cellular amino acid metabolic processGO:004576320.010
apoptotic mitochondrial changesGO:0008637570.010
purine ribonucleoside triphosphate metabolic processGO:00092054110.010
cilium morphogenesisGO:0060271750.010
positive regulation of proteasomal protein catabolic processGO:1901800350.010
regulation of microtubule based processGO:0032886740.010
gland developmentGO:0048732480.010
mitotic spindle organizationGO:0007052270.010
positive regulation of neural precursor cell proliferationGO:200017920.010

CASP8AP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.140
disease of cellular proliferationDOID:145661740.140
immune system diseaseDOID:29141550.082
disease of metabolismDOID:00146672950.030
nervous system diseaseDOID:8634310.012
neurodegenerative diseaseDOID:12891020.012
central nervous system diseaseDOID:3311860.012
hematopoietic system diseaseDOID:741000.010