Homo sapiens

0 known processes

PRODH2

proline dehydrogenase (oxidase) 2

(Aliases: HSPOX1)

PRODH2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
alpha ketoglutarate transportGO:001574210.918
urate transportGO:001574730.873
quorum sensingGO:000937210.796
carnitine transmembrane transportGO:190260330.744
short chain fatty acid importGO:001591310.725
transmembrane transportGO:00550853990.697
interspecies quorum sensingGO:005209710.546
cation transmembrane transportGO:00986552380.535
cation transportGO:00068123310.513
positive regulation of intestinal epithelial structure maintenanceGO:006073110.495
sodium independent organic anion transportGO:004325220.495
nicotinate transportGO:200114210.469
renal tubular secretionGO:009725410.464
anion transportGO:00068201610.415
ion transmembrane transportGO:00342203380.373
cellular amino acid metabolic processGO:00065201160.372
cellular amine metabolic processGO:0044106410.362
cellular ketone metabolic processGO:0042180800.353
system processGO:00030083490.352
g protein coupled receptor signaling pathwayGO:00071862070.285
response to oxygen containing compoundGO:19017003690.274
chemical homeostasisGO:00488783060.273
homeostasis of number of cells in a free living populationGO:004887410.261
regulation of cellular amino acid metabolic processGO:000652160.246
metal ion transportGO:00300012720.239
regulation of cellular ketone metabolic processGO:0010565500.239
ion homeostasisGO:00508012300.233
response to organic cyclic compoundGO:00140702040.230
amine metabolic processGO:0009308440.222
positive regulation of transportGO:00510503360.215
micturitionGO:006007330.210
quorum sensing involved in interaction with hostGO:005210610.205
organic hydroxy compound transportGO:0015850630.194
positive regulation of cellular amino acid metabolic processGO:004576430.183
regulation of cellular amine metabolic processGO:0033238110.183
cellular ion homeostasisGO:00068731680.177
positive regulation of cellular amine metabolic processGO:003324070.173
lipid metabolic processGO:00066293810.169
positive regulation of digestive system processGO:006045620.168
regulation of locomotionGO:00400123290.162
cellular chemical homeostasisGO:00550821800.160
regulation of ion transportGO:00432691890.152
short chain fatty acid transportGO:001591210.141
regulation of hormone levelsGO:00108171250.141
organic anion transportGO:00157111030.139
positive regulation of phosphorylationGO:00423273940.134
secretionGO:00469032540.133
divalent inorganic cation homeostasisGO:00725071360.124
sodium dependent organic cation transportGO:007071510.123
carboxylic acid transportGO:0046942630.122
response to nitrogen compoundGO:19016981840.122
negative regulation of multicellular organismal processGO:00512413170.121
metal ion homeostasisGO:00550651690.118
cellular homeostasisGO:00197251960.116
regulation of system processGO:00440571010.114
nitrogen compound transportGO:00717051910.112
divalent inorganic cation transportGO:00725111580.112
response to organonitrogen compoundGO:00102431560.110
synaptic transmission involved in micturitionGO:006008420.108
positive regulation of protein phosphorylationGO:00019343130.108
cellular cation homeostasisGO:00300031630.107
cellular divalent inorganic cation homeostasisGO:00725031280.106
calcium ion homeostasisGO:00550741220.104
cellular lipid metabolic processGO:00442553030.101
response to abiotic stimulusGO:00096283360.099
cation homeostasisGO:00550801890.095
regulation of phospholipase c activating g protein coupled receptor signaling pathwayGO:190073610.094
organonitrogen compound biosynthetic processGO:19015662000.090
cellular response to endogenous stimulusGO:00714953360.089
negative regulation of acetylcholine gated cation channel activityGO:190304910.089
regulation of cell migrationGO:00303342890.087
cellular metal ion homeostasisGO:00068751460.087
urate metabolic processGO:0046415110.087
cytosolic calcium ion homeostasisGO:0051480890.084
regulation of cellular component movementGO:00512703340.083
regulation of secretionGO:00510461940.083
organic acid transportGO:0015849650.079
lipid biosynthetic processGO:00086101770.079
peptidyl tyrosine modificationGO:00182121700.079
positive regulation of developmental processGO:00510943140.078
glycine importGO:003623310.078
peptidyl tyrosine phosphorylationGO:00181081700.076
regulation of response to woundingGO:19030341010.076
memoryGO:000761330.075
response to inorganic substanceGO:00100351270.072
cell activationGO:00017752130.072
inorganic cation transmembrane transportGO:00986621940.071
cellular response to organic cyclic compoundGO:00714071270.071
regulation of ion transmembrane transportGO:00347651320.071
visual learningGO:000854210.069
cellular calcium ion homeostasisGO:00068741170.068
inorganic ion transmembrane transportGO:00986602310.066
regulation of acetylcholine gated cation channel activityGO:190304810.066
postsynaptic membrane organizationGO:000194120.064
hormone transportGO:0009914680.064
anion transmembrane transportGO:0098656760.063
regulation of response to external stimulusGO:00321012220.062
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.062
mapk cascadeGO:00001652880.062
regulation of transmembrane transportGO:00347621390.061
lipid transportGO:0006869900.060
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.060
positive regulation of cytosolic calcium ion concentrationGO:0007204820.060
negative regulation of catalytic activityGO:00430863350.060
positive regulation of fibrinolysisGO:005191940.059
response to woundingGO:00096111680.059
cytoplasmic transportGO:00164823790.058
interspecies interaction between organismsGO:00444191560.058
renal system processGO:0003014250.057
immune responseGO:00069553070.057
negative regulation of protein metabolic processGO:00512483910.057
protein maturationGO:00516042330.056
regulation of cell motilityGO:20001452990.056
regulation of body fluid levelsGO:0050878990.055
regulation of proteolysisGO:00301622930.055
cytokine productionGO:00018162470.054
defense responseGO:00069523150.054
negative regulation of cell deathGO:00605483450.054
regulation of transferase activityGO:00513383550.054
regulation of cell differentiationGO:00455953930.053
negative regulation of cellular protein metabolic processGO:00322693530.053
regulation of secretion by cellGO:19035301770.052
cyclic nucleotide metabolic processGO:0009187820.052
protein processingGO:00164852260.051
post embryonic developmentGO:000979120.050
carboxylic acid biosynthetic processGO:0046394970.049
blood circulationGO:00080151130.049
secretion by cellGO:00329402260.049
regulation of cytokine productionGO:00018172320.049
negative regulation of protein maturationGO:19033181420.048
alcohol metabolic processGO:00060661140.047
response to drugGO:0042493810.047
locomotory behaviorGO:000762610.046
positive regulation of immune system processGO:00026842830.046
nervous system developmentGO:00073992930.046
carbohydrate derivative biosynthetic processGO:19011372070.045
regulation of protein maturationGO:19033171500.045
response to metal ionGO:0010038840.045
nucleoside phosphate biosynthetic processGO:19012931090.045
negative regulation of apoptotic processGO:00430663160.045
organic hydroxy compound metabolic processGO:19016151470.044
signal transduction by phosphorylationGO:00230142970.044
enzyme linked receptor protein signaling pathwayGO:00071673030.044
positive regulation of cellular component organizationGO:00511303760.044
regulation of mapk cascadeGO:00434082620.043
cell cell signalingGO:00072671550.043
multicellular organismal agingGO:001025930.042
anatomical structure homeostasisGO:00602491000.042
regulation of endopeptidase activityGO:00525481700.041
cellular response to nitrogen compoundGO:19016991440.041
purine ribonucleoside metabolic processGO:00461284370.041
regenerationGO:003109940.040
growthGO:00400072020.040
small molecule biosynthetic processGO:00442831570.040
wound healingGO:00420601150.039
inflammatory responseGO:0006954790.039
behaviorGO:00076101120.039
negative regulation of hydrolase activityGO:00513461820.039
regulation of cellular component biogenesisGO:00440872810.039
vesicle mediated transportGO:00161923710.039
lipid localizationGO:00108761060.039
glycerolipid metabolic processGO:00464861070.039
membrane organizationGO:00610242920.038
cellular response to organonitrogen compoundGO:00714171240.038
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.038
activation of protein kinase activityGO:0032147900.038
regulation of transporter activityGO:0032409820.038
activation of mapk activity by adrenergic receptor signaling pathwayGO:007188330.037
steroid metabolic processGO:0008202940.037
positive regulation of ion transportGO:0043270870.037
negative regulation of response to external stimulusGO:0032102830.036
positive regulation of locomotionGO:00400171860.036
response to lipidGO:00339932060.036
regulation of protein processingGO:00706131500.036
synaptic transmission glycinergicGO:006001210.036
organic acid biosynthetic processGO:0016053970.036
divalent metal ion transportGO:00708381520.036
positive regulation of cell proliferationGO:00082843010.036
actin filament based processGO:00300292240.035
regulation of protein localizationGO:00328802960.035
reactive oxygen species metabolic processGO:0072593750.035
negative regulation of protein processingGO:00109551420.035
regulation of kinase activityGO:00435493140.035
negative regulation of programmed cell deathGO:00430693210.035
organophosphate biosynthetic processGO:00904071630.035
cellular response to abiotic stimulusGO:00712141170.035
associative learningGO:000830610.034
muscle contractionGO:0006936730.034
positive regulation of protein kinase activityGO:00458601900.034
negative regulation of transportGO:00510511760.034
regulation of protein serine threonine kinase activityGO:00719001790.034
regulation of membrane potentialGO:0042391950.034
visual behaviorGO:000763220.034
negative regulation of developmental processGO:00510932470.033
regulation of protein kinase activityGO:00458592890.033
negative regulation of cellular component organizationGO:00511292350.033
regulation of homeostatic processGO:00328441210.033
regulation of reactive oxygen species metabolic processGO:2000377410.033
negative regulation of phosphate metabolic processGO:00459362670.033
multi organism cellular processGO:00447641560.033
determination of adult lifespanGO:000834020.033
response to hormoneGO:00097251750.032
symbiosis encompassing mutualism through parasitismGO:00444031560.032
positive regulation of blood coagulationGO:0030194110.032
cardiovascular system developmentGO:00723582620.032
response to cytokineGO:00340972320.032
positive regulation of cell motilityGO:20001471770.032
single organism membrane organizationGO:00448022680.031
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.031
regulation of wound healingGO:0061041560.031
regulation of peptidase activityGO:00525471800.031
purine containing compound biosynthetic processGO:0072522880.031
regulation of reactive oxygen species biosynthetic processGO:190342630.031
protein oligomerizationGO:00512591730.031
response to radiationGO:00093141510.031
response to biotic stimulusGO:00096072760.031
purine ribonucleotide biosynthetic processGO:0009152790.031
single organism carbohydrate metabolic processGO:00447231930.031
cell projection organizationGO:00300302520.030
negative regulation of hemostasisGO:1900047220.030
amino acid transportGO:0006865280.030
ribonucleoside catabolic processGO:00424544060.030
chemotaxisGO:00069351570.030
regulation of peptidyl tyrosine phosphorylationGO:00507301080.030
circulatory system developmentGO:00723592620.030
purine containing compound catabolic processGO:00725234110.030
proline transportGO:001582440.029
positive regulation of secretionGO:00510471160.029
female gamete generationGO:000729220.029
reactive nitrogen species metabolic processGO:200105730.029
negative regulation of endopeptidase activityGO:0010951840.029
sodium ion transmembrane transportGO:0035725590.029
negative regulation of proteolysisGO:00458611320.029
sulfur compound metabolic processGO:00067901010.029
single organism cellular localizationGO:19025803320.029
positive regulation of map kinase activityGO:0043406800.028
nucleoside triphosphate metabolic processGO:00091414220.028
positive regulation of cytokine productionGO:00018191670.028
regulation of transmembrane transporter activityGO:0022898740.028
response to hypoxiaGO:0001666960.028
calcium ion transportGO:00068161470.028
apoptotic signaling pathwayGO:00971902680.028
organic acid catabolic processGO:0016054710.028
regulation of ion transmembrane transporter activityGO:0032412720.028
positive regulation of cellular component movementGO:00512721810.028
cellular response to oxygen containing compoundGO:19017012760.028
monocarboxylic acid metabolic processGO:00327871850.028
maintenance of locationGO:00512351120.027
cellular response to growth factor stimulusGO:00713631970.027
positive regulation of reactive oxygen species metabolic processGO:2000379240.027
oxidation reduction processGO:00551143960.027
regulation of coagulationGO:0050818440.027
response to decreased oxygen levelsGO:0036293960.027
reactive oxygen species biosynthetic processGO:190340940.027
regulation of metal ion transportGO:00109591200.027
cell developmentGO:00484683280.027
response to growth factorGO:00708482050.026
response to external biotic stimulusGO:00432072610.026
digestionGO:0007586220.026
positive regulation of programmed cell deathGO:00430682490.026
negative regulation of phosphorus metabolic processGO:00105632670.026
response to oxygen levelsGO:00704821000.026
positive regulation of nucleotide metabolic processGO:00459812300.026
cyclic purine nucleotide metabolic processGO:0052652600.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
multicellular organismal homeostasisGO:0048871670.026
regulation of purine nucleotide metabolic processGO:19005422640.025
limbic system developmentGO:002176130.025
alpha amino acid metabolic processGO:1901605720.025
response to nutrient levelsGO:0031667810.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
nucleotide catabolic processGO:00091664080.024
regulation of camp metabolic processGO:0030814520.024
positive regulation of transferase activityGO:00513472270.024
positive regulation of apoptotic processGO:00430652460.024
regulation of behaviorGO:0050795820.024
positive regulation of mapk cascadeGO:00434101900.024
kinin cascadeGO:000225410.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.024
response to transition metal nanoparticleGO:1990267290.024
cellular modified amino acid metabolic processGO:0006575640.024
nucleoside phosphate catabolic processGO:19012924120.024
taxisGO:00423301570.024
positive regulation of cell adhesionGO:0045785840.024
muscle system processGO:0003012810.024
purine nucleoside catabolic processGO:00061523980.023
central nervous system developmentGO:00074171230.023
activation of mapk activityGO:0000187450.023
response to extracellular stimulusGO:0009991850.023
hindbrain developmentGO:003090230.023
positive regulation of catabolic processGO:00098963100.023
negative regulation of wound healingGO:0061045250.023
response to other organismGO:00517072610.023
regulation of hormone secretionGO:0046883570.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
regulation of apoptotic signaling pathwayGO:20012331750.023
purine nucleotide catabolic processGO:00061954050.023
cellular response to cytokine stimulusGO:00713451810.023
positive regulation of hydrolase activityGO:00513453310.023
response to light stimulusGO:0009416870.023
positive regulation of hemostasisGO:1900048110.023
camp biosynthetic processGO:0006171470.023
positive regulation of cell deathGO:00109422630.023
protein catabolic processGO:00301633250.023
sleepGO:003043120.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
response to organophosphorusGO:0046683410.022
lipid catabolic processGO:0016042840.022
purine nucleotide biosynthetic processGO:0006164840.022
cell morphogenesisGO:00009022960.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
angiogenesisGO:00015251470.022
erk1 and erk2 cascadeGO:00703711040.022
somatostatin signaling pathwayGO:003817010.022
behavioral response to ethanolGO:004814920.022
amino acid betaine transportGO:001583840.022
ribonucleotide catabolic processGO:00092614050.022
cellular response to external stimulusGO:00714961110.022
blood vessel morphogenesisGO:00485141620.022
immune effector processGO:00022521590.022
glycine transportGO:001581630.022
regulation of blood coagulationGO:0030193420.022
glycoprotein metabolic processGO:00091001100.022
sensory perceptionGO:00076001030.021
regulation of establishment of protein localizationGO:00702012420.021
atp catabolic processGO:00062001570.021
regulation of branching involved in ureteric bud morphogenesisGO:009018930.021
small molecule catabolic processGO:0044282920.021
positive regulation of kinase activityGO:00336742040.021
neurological system processGO:00508771630.021
ribonucleotide biosynthetic processGO:0009260810.021
positive regulation of protein serine threonine kinase activityGO:00719021190.021
monocarboxylic acid biosynthetic processGO:0072330670.021
organophosphate catabolic processGO:00464344300.021
circulatory system processGO:00030131130.021
positive regulation of erk1 and erk2 cascadeGO:0070374750.021
peptide secretionGO:0002790510.021
morphogenesis of embryonic epitheliumGO:001633140.021
cyclic nucleotide biosynthetic processGO:0009190610.021
cellular response to hormone stimulusGO:00328701250.021
negative regulation of blood coagulationGO:0030195220.021
biological adhesionGO:00226103310.021
positive regulation of cell migrationGO:00303351720.021
regulation of dna metabolic processGO:00510521530.021
fatty acid metabolic processGO:00066311150.020
positive regulation of reactive oxygen species biosynthetic processGO:190342820.020
positive regulation of purine nucleotide metabolic processGO:19005442270.020
regulation of immune responseGO:00507762010.020
regulation of nucleotide biosynthetic processGO:0030808500.020
leukocyte migrationGO:00509001070.020
regulation of cell developmentGO:00602841610.020
response to disaccharideGO:003428510.020
carbohydrate metabolic processGO:00059752070.020
negative regulation of response to woundingGO:1903035470.020
negative regulation of locomotionGO:00400131180.020
regulation of anatomical structure morphogenesisGO:00226032860.020
regulation of cell activationGO:00508651250.020
tissue homeostasisGO:0001894630.019
dephosphorylationGO:00163112090.019
innate immune responseGO:00450871780.019
negative regulation of intracellular signal transductionGO:19025321830.019
nucleotide biosynthetic processGO:00091651090.019
regulation of cell cycleGO:00517263930.019
regulation of growthGO:00400081650.019
positive regulation of response to external stimulusGO:0032103880.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
regulation of nucleotide metabolic processGO:00061402690.019
regulation of defense responseGO:00313471540.019
sequestering of calcium ionGO:0051208170.019
glycerophospholipid metabolic processGO:0006650840.019
tissue regenerationGO:004224630.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
purine ribonucleoside catabolic processGO:00461303980.018
peptide transportGO:0015833740.018
regulation of synaptic plasticityGO:004816730.018
regulation of calcium ion transportGO:0051924790.018
phospholipid metabolic processGO:0006644990.018
sequestering of metal ionGO:0051238240.018
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200150.018
response to oxidative stressGO:00069791210.018
potassium ion transportGO:0006813620.018
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.018
ameboidal type cell migrationGO:00016671350.018
positive regulation of homeostatic processGO:0032846470.018
matingGO:000761810.018
response to salt stressGO:000965130.018
positive regulation of secretion by cellGO:19035321080.018
regulation of protein secretionGO:0050708860.018
positive regulation of calcium ion transportGO:0051928510.018
positive regulation of cellular catabolic processGO:00313312840.018
purine ribonucleotide catabolic processGO:00091544040.018
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189180.018
nucleoside monophosphate catabolic processGO:00091251590.018
positive regulation of camp biosynthetic processGO:0030819350.018
nucleoside catabolic processGO:00091644080.018
amide transportGO:0042886760.018
negative regulation of cytokine productionGO:0001818820.018
nucleoside triphosphate catabolic processGO:00091433940.018
negative regulation of cell proliferationGO:00082852280.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.018
negative regulation of cellular amine metabolic processGO:003323930.017
cell adhesionGO:00071553250.017
monovalent inorganic cation transportGO:00156721280.017
response to fungusGO:000962040.017
9 cis retinoic acid metabolic processGO:004290510.017
actin cytoskeleton organizationGO:00300362070.017
regulation of cell cycle processGO:00105642660.017
atp metabolic processGO:00460341760.017
leukocyte activationGO:00453211640.017
regulation of peptide secretionGO:0002791420.017
small gtpase mediated signal transductionGO:0007264780.017
adult locomotory behaviorGO:000834410.017
response to sucroseGO:000974410.017
protein secretionGO:0009306980.017
circadian behaviorGO:004851220.017
cell growthGO:00160491600.017
regulation of lipid metabolic processGO:0019216960.017
positive regulation of synaptic transmissionGO:005080640.016
positive regulation of plasminogen activationGO:001075630.016
intracellular protein transportGO:00068862700.016
carboxylic acid catabolic processGO:0046395710.016
glycosyl compound catabolic processGO:19016584130.016
astrocyte differentiationGO:004870840.016
regulation of vasculature developmentGO:1901342970.016
peripheral nervous system developmentGO:000742220.016
regulation of cyclic nucleotide biosynthetic processGO:0030802490.016
positive regulation of nucleotide biosynthetic processGO:0030810380.016
blood vessel developmentGO:00015681720.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
reproductive processGO:00224141060.016
cellular response to disaccharide stimulusGO:007132410.016
serotonin receptor signaling pathwayGO:0007210110.016
positive regulation of cell developmentGO:0010720920.016
inner ear morphogenesisGO:004247240.016
epithelial cell migrationGO:00106311190.016
regulation of epithelial cell migrationGO:0010632930.016
response to acid chemicalGO:0001101660.016
cellular component morphogenesisGO:00329893140.016
protein localization to organelleGO:00333652800.016
brain developmentGO:0007420970.016
regulation of cellular response to stressGO:00801352440.016
head developmentGO:00603221080.016
regulation of map kinase activityGO:00434051080.016
purine nucleoside monophosphate catabolic processGO:00091281580.016
response to axon injuryGO:004867810.016
defense response to fungusGO:005083240.016
blood coagulationGO:0007596760.016
calcium ion transmembrane transportGO:0070588760.015
protein homooligomerizationGO:00512601000.015
ribose phosphate biosynthetic processGO:0046390820.015
nucleoside monophosphate metabolic processGO:00091231910.015
negative regulation of peptidase activityGO:0010466910.015
defense response to other organismGO:00985421290.015
glial cell migrationGO:000834740.015
interaction with hostGO:0051701420.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
gas transportGO:001566930.015
positive regulation of cell differentiationGO:00455972110.015
mitochondrion organizationGO:00070051560.015
cell chemotaxisGO:00603261120.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
vasculature developmentGO:00019441810.015
protein targetingGO:00066051870.015
regulation of neuronal synaptic plasticityGO:004816810.015
multicellular organismal signalingGO:0035637340.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
serotonin uptakeGO:005161020.015
epithelial cell differentiationGO:00308551410.015
negative regulation of protein modification processGO:00314002000.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
response to purine containing compoundGO:0014074400.015
muscle cell cellular homeostasisGO:004671630.015
oogenesisGO:004847720.015

PRODH2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
renal tubular transport diseaseDOID:447110.648
kidney diseaseDOID:557360.648
urinary system diseaseDOID:18400.648
disease of metabolismDOID:00146672950.168
inherited metabolic disorderDOID:6552420.093
sensory system diseaseDOID:00501552030.038
nervous system diseaseDOID:8634310.038
immune system diseaseDOID:29141550.034
disease of cellular proliferationDOID:145661740.025
acquired metabolic diseaseDOID:0060158580.024
central nervous system diseaseDOID:3311860.023
eye and adnexa diseaseDOID:14921500.021
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
retinal diseaseDOID:56791180.020
eye diseaseDOID:56141490.020
night blindnessDOID:8499100.020
musculoskeletal system diseaseDOID:172230.018
hematopoietic system diseaseDOID:741000.017