Homo sapiens

0 known processes

NGEF

neuronal guanine nucleotide exchange factor

(Aliases: EPHEXIN,ARHGEF27)

NGEF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organophosphate catabolic processGO:00464344300.116
Human Mouse Rat
ribonucleoside triphosphate metabolic processGO:00091994120.108
Human Mouse Rat
regulation of gtpase activityGO:00430871800.104
Human Mouse Rat
purine ribonucleoside triphosphate metabolic processGO:00092054110.101
Human Mouse Rat
purine nucleoside triphosphate catabolic processGO:00091463920.092
Human Mouse Rat
regulation of nucleotide metabolic processGO:00061402690.091
Human Mouse Rat
glycosyl compound catabolic processGO:19016584130.089
Human Mouse Rat
gtp catabolic processGO:00061842370.086
Human Mouse Rat
purine ribonucleotide catabolic processGO:00091544040.079
Human Mouse Rat
gtp metabolic processGO:00460392390.077
Human Mouse Rat
purine ribonucleoside metabolic processGO:00461284370.076
Human Mouse Rat
regulation of purine nucleotide metabolic processGO:19005422640.069
Human Mouse Rat
ribonucleotide catabolic processGO:00092614050.060
Human Mouse Rat
post embryonic developmentGO:000979120.057
nucleotide catabolic processGO:00091664080.055
Human Mouse Rat
positive regulation of nucleotide catabolic processGO:00308131850.054
Human
purine nucleoside catabolic processGO:00061523980.053
Human Mouse Rat
rho protein signal transductionGO:0007266260.051
guanosine containing compound catabolic processGO:19010692390.051
Human Mouse Rat
regulation of nucleotide catabolic processGO:00308112050.049
Human Mouse Rat
cellular amino acid metabolic processGO:00065201160.047
nucleoside triphosphate catabolic processGO:00091433940.047
Human Mouse Rat
regulation of cellular ketone metabolic processGO:0010565500.046
ribonucleoside catabolic processGO:00424544060.045
Human Mouse Rat
positive regulation of hydrolase activityGO:00513453310.043
Human
positive regulation of catabolic processGO:00098963100.042
Human
nucleoside catabolic processGO:00091644080.042
Human Mouse Rat
purine ribonucleoside triphosphate catabolic processGO:00092073910.042
Human Mouse Rat
positive regulation of protein phosphorylationGO:00019343130.041
nucleoside phosphate catabolic processGO:19012924120.039
Human Mouse Rat
nucleoside triphosphate metabolic processGO:00091414220.039
Human Mouse Rat
positive regulation of ras gtpase activityGO:00323201170.038
Human
neuromuscular junction developmentGO:000752830.038
regulation of nucleoside metabolic processGO:00091182090.037
Human Mouse Rat
response to increased oxygen levelsGO:003629640.037
regulation of cell cycleGO:00517263930.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
Human Mouse Rat
small gtpase mediated signal transductionGO:0007264780.037
purine nucleoside triphosphate metabolic processGO:00091444120.035
Human Mouse Rat
regulation of ras gtpase activityGO:00323181280.035
Human
negative regulation of catalytic activityGO:00430863350.034
regenerationGO:003109940.033
positive regulation of nucleoside metabolic processGO:00459791860.033
Human
immune responseGO:00069553070.032
establishment or maintenance of cytoskeleton polarityGO:003095230.032
positive regulation of gtp catabolic processGO:00331261660.032
Human
transmembrane transportGO:00550853990.032
regulation of cellular amine metabolic processGO:0033238110.032
positive regulation of gtpase activityGO:00435471660.032
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.031
Human
regulation of cytoskeleton organizationGO:00514931770.031
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.030
Human
anterior posterior axis specification embryoGO:000859520.030
lipid metabolic processGO:00066293810.030
inner ear morphogenesisGO:004247240.029
amine metabolic processGO:0009308440.029
cellular ketone metabolic processGO:0042180800.029
purine containing compound catabolic processGO:00725234110.029
Human Mouse Rat
regulation of actin filament based processGO:00329701410.029
Human
cell adhesionGO:00071553250.028
regulation of small gtpase mediated signal transductionGO:00510561560.027
Human
positive regulation of cellular amino acid metabolic processGO:004576430.027
purine nucleotide catabolic processGO:00061954050.026
Human Mouse Rat
anterior posterior axis specificationGO:000994820.026
cellular amine metabolic processGO:0044106410.026
regulation of protein localizationGO:00328802960.026
Human
regulation of actin cytoskeleton organizationGO:00329561160.026
Human
biological adhesionGO:00226103310.025
regulation of ras protein signal transductionGO:00465781550.024
Human
protein maturationGO:00516042330.024
spermatid differentiationGO:004851540.024
regulation of actin filament polymerizationGO:0030833500.024
regulation of purine nucleotide catabolic processGO:00331212050.024
Human Mouse Rat
regulation of cellular amino acid metabolic processGO:000652160.023
positive regulation of kinase activityGO:00336742040.023
epithelium developmentGO:00604292270.023
positive regulation of cellular catabolic processGO:00313312840.023
Human
ras protein signal transductionGO:0007265730.023
positive regulation of developmental processGO:00510943140.023
cytoplasmic transportGO:00164823790.023
system processGO:00030083490.023
purine ribonucleoside catabolic processGO:00461303980.023
Human Mouse Rat
microtubule cytoskeleton organizationGO:00002261760.023
positive regulation of cellular component organizationGO:00511303760.023
Human
positive regulation of protein kinase activityGO:00458601900.022
response to oxygen containing compoundGO:19017003690.022
mitotic cell cycleGO:00002783260.022
protein localization to organelleGO:00333652800.022
regulation of establishment of protein localizationGO:00702012420.022
Human
positive regulation of nucleotide metabolic processGO:00459812300.022
Human
actin filament based processGO:00300292240.022
Human
regulation of transferase activityGO:00513383550.022
microtubule based processGO:00070172100.021
regulation of rho gtpase activityGO:0032319660.021
Human
protein processingGO:00164852260.021
single organism cellular localizationGO:19025803320.021
Human
cellular macromolecule catabolic processGO:00442653800.021
actin filament organizationGO:00070151280.020
cdc42 protein signal transductionGO:003248840.020
cellular lipid metabolic processGO:00442553030.020
defense responseGO:00069523150.020
small molecule biosynthetic processGO:00442831570.020
mitochondrion organizationGO:00070051560.020
single organism carbohydrate metabolic processGO:00447231930.020
tripartite regional subdivisionGO:000735120.020
morphogenesis of embryonic epitheliumGO:001633140.020
negative regulation of hydrolase activityGO:00513461820.020
cerebral cortex cell migrationGO:002179530.020
actin cytoskeleton organizationGO:00300362070.019
Human
regulation of cellular component biogenesisGO:00440872810.019
innate immune responseGO:00450871780.019
cellular protein catabolic processGO:00442572610.019
organonitrogen compound biosynthetic processGO:19015662000.019
locomotory behaviorGO:000762610.019
oogenesisGO:004847720.019
regulation of apoptotic signaling pathwayGO:20012331750.019
dna repairGO:00062811980.019
cellular response to growth factor stimulusGO:00713631970.018
positive regulation of cellular amine metabolic processGO:003324070.018
regulation of cell adhesionGO:00301551660.018
regulation of growthGO:00400081650.018
blastocyst developmentGO:000182430.018
compound eye developmentGO:004874910.018
apoptotic signaling pathwayGO:00971902680.018
positive regulation of phosphorylationGO:00423273940.018
regulation of protein transportGO:00512232130.018
regulation of kinase activityGO:00435493140.018
protein ubiquitinationGO:00165673140.018
establishment of tissue polarityGO:000716430.018
positive regulation of organelle organizationGO:00106381950.018
embryonic epithelial tube formationGO:000183840.018
regulation of protein complex assemblyGO:00432541470.018
regulation of protein processingGO:00706131500.018
forebrain generation of neuronsGO:002187230.018
inorganic cation transmembrane transportGO:00986621940.018
nucleocytoplasmic transportGO:00069131760.017
regulation of protein kinase activityGO:00458592890.017
negative regulation of cell proliferationGO:00082852280.017
matingGO:000761810.017
regulation of protein serine threonine kinase activityGO:00719001790.017
regulation of intracellular transportGO:00323861950.017
dephosphorylationGO:00163112090.017
regulation of protein polymerizationGO:0032271630.017
cellular response to endogenous stimulusGO:00714953360.017
central nervous system developmentGO:00074171230.017
regulation of actin polymerization or depolymerizationGO:0008064560.017
stem cell divisionGO:001714520.017
regulation of cell cycle processGO:00105642660.016
vesicle mediated transportGO:00161923710.016
negative regulation of phosphorus metabolic processGO:00105632670.016
establishment of planar polarityGO:000173630.016
negative regulation of cellular protein metabolic processGO:00322693530.016
regulation of protein maturationGO:19033171500.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
segmentationGO:003528240.016
positive regulation of transferase activityGO:00513472270.016
positive regulation of protein serine threonine kinase activityGO:00719021190.016
nuclear transportGO:00511691790.016
rhythmic behaviorGO:000762220.016
positive regulation of protein complex assemblyGO:0031334860.016
positive regulation of cellular component biogenesisGO:00440891580.016
negative regulation of protein processingGO:00109551420.016
hindbrain developmentGO:003090230.015
regulation of multi organism processGO:00439001570.015
memoryGO:000761330.015
response to growth factorGO:00708482050.015
inorganic ion transmembrane transportGO:00986602310.015
mitotic cell cycle processGO:19030472860.015
dna replicationGO:00062601160.015
actin mediated cell contractionGO:0070252120.015
atp metabolic processGO:00460341760.015
regulation of endopeptidase activityGO:00525481700.015
blastoderm segmentationGO:000735020.015
negative regulation of proteolysisGO:00458611320.015
negative regulation of phosphate metabolic processGO:00459362670.014
viral processGO:00160321460.014
anion transportGO:00068201610.014
regulation of proteolysisGO:00301622930.014
tissue regenerationGO:004224630.014
ion homeostasisGO:00508012300.014
viral life cycleGO:00190581320.014
mitotic spindle elongationGO:000002240.014
guanosine containing compound metabolic processGO:19010682440.014
Human Mouse Rat
intracellular mrna localizationGO:000829810.014
semaphorin plexin signaling pathwayGO:007152640.014
multi organism cellular processGO:00447641560.014
cation transportGO:00068123310.014
female gamete generationGO:000729220.014
nervous system developmentGO:00073992930.014
Mouse Rat
extrinsic apoptotic signaling pathwayGO:00971911190.014
regulation of cellular response to stressGO:00801352440.014
monocarboxylic acid metabolic processGO:00327871850.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
protein catabolic processGO:00301633250.014
post embryonic organ developmentGO:004856910.013
regulation of gtp catabolic processGO:00331241800.013
Human Mouse Rat
organ formationGO:004864530.013
response to abiotic stimulusGO:00096283360.013
establishment of protein localization to membraneGO:00901501210.013
Human
single organism cell adhesionGO:00986021790.013
regulation of response to external stimulusGO:00321012220.013
salivary gland morphogenesisGO:000743540.013
regulation of cell cell adhesionGO:0022407570.013
neurological system processGO:00508771630.013
ribonucleoprotein complex assemblyGO:0022618780.013
syncytium formation by plasma membrane fusionGO:000076820.013
divalent metal ion transportGO:00708381520.013
spermatid developmentGO:000728640.013
negative regulation of programmed cell deathGO:00430693210.013
negative regulation of cellular amine metabolic processGO:003323930.013
spindle elongationGO:005123140.013
interspecies interaction between organismsGO:00444191560.013
cellular response to dna damage stimulusGO:00069743790.013
cell projection organizationGO:00300302520.013
Mouse Rat
positive regulation of apoptotic signaling pathwayGO:2001235700.013
single organismal cell cell adhesionGO:00163371480.013
regulation of intracellular protein transportGO:00331571230.013
nitrogen compound transportGO:00717051910.013
metencephalon developmentGO:002203720.013
negative regulation of protein maturationGO:19033181420.013
positive regulation of synaptic transmissionGO:005080640.013
determination of adult lifespanGO:000834020.013
positive regulation of programmed cell deathGO:00430682490.013
positive regulation of protein transportGO:00512221350.013
forebrain neuron developmentGO:002188420.013
regulation of actin filament lengthGO:0030832560.013
protein localization to nucleusGO:00345041360.013
protein targetingGO:00066051870.013
signal transduction by phosphorylationGO:00230142970.012
myoblast fusionGO:000752010.012
protein modification by small protein conjugationGO:00324463420.012
actin polymerization or depolymerizationGO:0008154560.012
taxisGO:00423301570.012
Human
single organism reproductive processGO:0044702980.012
cell divisionGO:00513011680.012
growthGO:00400072020.012
intracellular protein transportGO:00068862700.012
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.012
positive regulation of transportGO:00510503360.012
cardiac muscle cell contractionGO:008600340.012
cell morphogenesisGO:00009022960.012
Mouse Rat
regulation of mapk cascadeGO:00434082620.012
positive regulation of mapk cascadeGO:00434101900.012
actin filament polymerizationGO:0030041450.012
reactive oxygen species metabolic processGO:0072593750.012
response to axon injuryGO:004867810.012
regulation of anatomical structure sizeGO:00900661010.012
negative regulation of protein metabolic processGO:00512483910.012
oocyte developmentGO:004859910.012
regulation of peptidase activityGO:00525471800.012
rna interferenceGO:001624640.012
negative regulation of cell deathGO:00605483450.012
negative regulation of apoptotic processGO:00430663160.012
regulation of synaptic plasticityGO:004816730.012
circadian behaviorGO:004851220.012
protein polymerizationGO:0051258710.012
reactive oxygen species biosynthetic processGO:190340940.012
negative regulation of multicellular organismal processGO:00512413170.012
Mouse Rat
negative regulation of endopeptidase activityGO:0010951840.012
organic acid biosynthetic processGO:0016053970.011
cation transmembrane transportGO:00986552380.011
response to nitrogen compoundGO:19016981840.011
peripheral nervous system developmentGO:000742220.011
regulation of anatomical structure morphogenesisGO:00226032860.011
Mouse Rat
rab protein signal transductionGO:003248240.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
lipid biosynthetic processGO:00086101770.011
nuclear importGO:00511701060.011
cell projection assemblyGO:00300311260.011
neural tube formationGO:000184130.011
g protein coupled receptor signaling pathwayGO:00071862070.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
cellular response to oxygen containing compoundGO:19017012760.011
negative regulation of phosphatase activityGO:0010923610.011
carbohydrate derivative biosynthetic processGO:19011372070.011
regulation of mitotic cell cycleGO:00073461890.011
protein oligomerizationGO:00512591730.011
maintenance of locationGO:00512351120.011
oocyte differentiationGO:000999420.011
cochlea developmentGO:009010210.011
mapk cascadeGO:00001652880.011
modification dependent protein catabolic processGO:00199412090.011
organelle fissionGO:00482851490.011
metal ion transportGO:00300012720.011
neural crest cell developmentGO:001403230.011
cuticle developmentGO:004233510.011
cellular response to abiotic stimulusGO:00712141170.011
regulation of rho protein signal transductionGO:0035023790.011
Human
endocytosisGO:00068971590.011
nerve developmentGO:002167540.011
negative regulation of cell cycleGO:00457861930.011
ion transmembrane transportGO:00342203380.011
motor neuron axon guidanceGO:000804520.011
adult locomotory behaviorGO:000834410.011
skin developmentGO:0043588760.011
endomembrane system organizationGO:00102561960.011
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.011
single organism membrane organizationGO:00448022680.010
Human
epidermis morphogenesisGO:004873030.010
actin filament based movementGO:0030048170.010
regulation of cellular component sizeGO:0032535820.010
positive regulation of immune system processGO:00026842830.010
carboxylic acid biosynthetic processGO:0046394970.010
negative regulation of peptidase activityGO:0010466910.010
negative regulation of growthGO:0045926970.010
cerebellum developmentGO:002154920.010
positive regulation of map kinase activityGO:0043406800.010
negative regulation of epidermal cell differentiationGO:004560540.010
regulation of protein targetingGO:1903533910.010
rna localizationGO:0006403410.010
regulation of cell differentiationGO:00455953930.010
Mouse Rat
mitotic nuclear divisionGO:00070671190.010
positive regulation of rho gtpase activityGO:0032321560.010
Human
regulation of phosphatase activityGO:0010921810.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
protein targeting to nucleusGO:00447441040.010
specification of organ identityGO:001009230.010
primary neural tube formationGO:001402030.010
sensory perception of painGO:001923340.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
regulation of cell divisionGO:00513021160.010
regulation of viral processGO:00507921030.010
response to fungusGO:000962040.010
non canonical wnt signaling pathway via mapk cascadeGO:003803040.010

NGEF disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.023
nervous system diseaseDOID:8634310.022
central nervous system diseaseDOID:3311860.022
musculoskeletal system diseaseDOID:172230.017
urinary system diseaseDOID:18400.016
connective tissue diseaseDOID:651090.015
sensory system diseaseDOID:00501552030.015
organ system cancerDOID:00506861640.014
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
inherited metabolic disorderDOID:6552420.013
kidney diseaseDOID:557360.011
bone diseaseDOID:0080001880.011
eye and adnexa diseaseDOID:14921500.011
retinal degenerationDOID:8466890.011
eye diseaseDOID:56141490.011
retinal diseaseDOID:56791180.011
brain diseaseDOID:936730.010