Homo sapiens

45 known processes

NEFL

neurofilament, light polypeptide

(Aliases: CMT1F,NF68,NFL,FLJ53642,CMT2E,NF-L)

NEFL biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neurofilament cytoskeleton organizationGO:006005220.797
neurofilament bundle assemblyGO:003369320.289
cell developmentGO:00484683280.197
regulation of cellular ketone metabolic processGO:0010565500.175
small gtpase mediated signal transductionGO:0007264780.156
ras protein signal transductionGO:0007265730.148
cellular amino acid metabolic processGO:00065201160.127
regulation of cellular amine metabolic processGO:0033238110.124
system processGO:00030083490.122
secretionGO:00469032540.115
regulation of cellular component movementGO:00512703340.115
regulation of cell developmentGO:00602841610.114
regulation of secretion by cellGO:19035301770.109
nucleoside triphosphate catabolic processGO:00091433940.108
positive regulation of cellular component organizationGO:00511303760.108
response to oxygen containing compoundGO:19017003690.107
secretion by cellGO:00329402260.106
neuron differentiationGO:00301821380.100
amine metabolic processGO:0009308440.099
cellular component morphogenesisGO:00329893140.099
lipid metabolic processGO:00066293810.093
cell projection organizationGO:00300302520.091
ion transmembrane transportGO:00342203380.091
cell cell signalingGO:00072671550.087
positive regulation of cellular amine metabolic processGO:003324070.086
cell morphogenesisGO:00009022960.082
generation of neuronsGO:00486991520.081
neuron projection developmentGO:00311751060.080
negative regulation of multicellular organismal processGO:00512413170.080
negative regulation of developmental processGO:00510932470.079
nervous system developmentGO:00073992930.078
negative regulation of protein metabolic processGO:00512483910.075
positive regulation of developmental processGO:00510943140.075
cellular ketone metabolic processGO:0042180800.074
cellular amine metabolic processGO:0044106410.072
ribonucleotide catabolic processGO:00092614050.071
regulation of secretionGO:00510461940.071
regulation of purine nucleotide metabolic processGO:19005422640.070
regulation of cell morphogenesis involved in differentiationGO:0010769830.070
positive regulation of catabolic processGO:00098963100.067
cell projection morphogenesisGO:00488581290.066
regulation of cell differentiationGO:00455953930.066
regulation of cellular component biogenesisGO:00440872810.065
response to organic cyclic compoundGO:00140702040.065
enzyme linked receptor protein signaling pathwayGO:00071673030.064
gtp metabolic processGO:00460392390.064
glycosyl compound catabolic processGO:19016584130.063
regulation of ras protein signal transductionGO:00465781550.063
purine ribonucleoside triphosphate metabolic processGO:00092054110.063
purine containing compound catabolic processGO:00725234110.062
regulation of cell morphogenesisGO:00226041530.062
cellular response to endogenous stimulusGO:00714953360.062
ribonucleoside triphosphate catabolic processGO:00092033910.061
regulation of locomotionGO:00400123290.061
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.060
nucleotide catabolic processGO:00091664080.058
regulation of nucleotide metabolic processGO:00061402690.057
positive regulation of cellular amino acid metabolic processGO:004576430.057
positive regulation of nucleotide metabolic processGO:00459812300.055
purine ribonucleoside triphosphate catabolic processGO:00092073910.055
negative regulation of cellular component organizationGO:00511292350.054
regulation of cellular amino acid metabolic processGO:000652160.053
regulation of cell motilityGO:20001452990.053
regulation of hormone levelsGO:00108171250.052
regulation of response to dna damage stimulusGO:2001020940.052
cell adhesionGO:00071553250.052
positive regulation of purine nucleotide metabolic processGO:19005442270.052
positive regulation of cellular catabolic processGO:00313312840.052
locomotory behaviorGO:000762610.052
regulation of anatomical structure morphogenesisGO:00226032860.052
nucleoside catabolic processGO:00091644080.051
regulation of microtubule based processGO:0032886740.051
negative regulation of cellular protein metabolic processGO:00322693530.051
gtp catabolic processGO:00061842370.051
inorganic cation transmembrane transportGO:00986621940.051
guanosine containing compound metabolic processGO:19010682440.051
memoryGO:000761330.051
regulation of neuron differentiationGO:0045664700.050
neuron developmentGO:00486661130.050
cellular macromolecule catabolic processGO:00442653800.050
response to lipidGO:00339932060.050
limbic system developmentGO:002176130.050
negative regulation of cell developmentGO:0010721480.050
protein modification by small protein conjugationGO:00324463420.050
head developmentGO:00603221080.049
regulation of synaptic plasticityGO:004816730.049
regulation of nervous system developmentGO:0051960880.049
positive regulation of cell differentiationGO:00455972110.049
single organism cellular localizationGO:19025803320.049
nucleoside triphosphate metabolic processGO:00091414220.049
regulation of intracellular transportGO:00323861950.049
neurogenesisGO:00220081690.048
regulation of purine nucleotide catabolic processGO:00331212050.048
response to abiotic stimulusGO:00096283360.048
positive regulation of transportGO:00510503360.047
purine nucleotide catabolic processGO:00061954050.046
microtubule based processGO:00070172100.046
positive regulation of cell developmentGO:0010720920.046
cytoplasmic transportGO:00164823790.045
purine ribonucleoside catabolic processGO:00461303980.045
positive regulation of cell proliferationGO:00082843010.045
ribonucleoside catabolic processGO:00424544060.045
transmembrane transportGO:00550853990.045
organophosphate catabolic processGO:00464344300.045
brain developmentGO:0007420970.045
purine ribonucleotide catabolic processGO:00091544040.045
guanosine containing compound catabolic processGO:19010692390.045
cell morphogenesis involved in differentiationGO:00009041440.044
purine nucleoside catabolic processGO:00061523980.044
positive regulation of apoptotic processGO:00430652460.044
purine nucleoside triphosphate catabolic processGO:00091463920.044
regulation of neuron projection developmentGO:0010975570.043
single organism membrane organizationGO:00448022680.043
purine nucleoside triphosphate metabolic processGO:00091444120.043
regulation of small gtpase mediated signal transductionGO:00510561560.043
central nervous system developmentGO:00074171230.043
neurological system processGO:00508771630.042
regulation of sequence specific dna binding transcription factor activityGO:00510902110.042
microtubule based movementGO:0007018320.042
purine ribonucleoside metabolic processGO:00461284370.042
regulation of neurotransmitter secretionGO:004692830.041
regulation of nucleotide catabolic processGO:00308112050.041
cellular response to dna damage stimulusGO:00069743790.040
neuromuscular junction developmentGO:000752830.040
chemical homeostasisGO:00488783060.040
positive regulation of phosphorylationGO:00423273940.039
cellular lipid metabolic processGO:00442553030.039
regulation of neurogenesisGO:0050767820.039
regulation of cell migrationGO:00303342890.039
growthGO:00400072020.038
cellular response to oxygen containing compoundGO:19017012760.038
nucleoside phosphate catabolic processGO:19012924120.038
cation transportGO:00068123310.038
regulation of gtp catabolic processGO:00331241800.037
ribonucleoside triphosphate metabolic processGO:00091994120.037
regulation of nucleoside metabolic processGO:00091182090.037
response to organonitrogen compoundGO:00102431560.037
membrane organizationGO:00610242920.036
protein catabolic processGO:00301633250.036
response to biotic stimulusGO:00096072760.036
microtubule cytoskeleton organizationGO:00002261760.036
positive regulation of immune system processGO:00026842830.036
epithelial cell differentiationGO:00308551410.036
regulation of ion transportGO:00432691890.036
associative learningGO:000830610.036
vesicle mediated transportGO:00161923710.035
cell fate determinationGO:000170930.035
protein processingGO:00164852260.035
axon cargo transportGO:000808820.035
positive regulation of cell deathGO:00109422630.035
neurotransmitter secretionGO:000726940.035
positive regulation of hydrolase activityGO:00513453310.035
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.034
negative regulation of synaptic transmissionGO:005080520.034
organophosphate biosynthetic processGO:00904071630.034
response to external biotic stimulusGO:00432072610.033
regulation of membrane potentialGO:0042391950.033
protein localization to organelleGO:00333652800.033
positive regulation of protein transportGO:00512221350.032
regulation of mapk cascadeGO:00434082620.032
organonitrogen compound biosynthetic processGO:19015662000.032
regulation of cellular response to stressGO:00801352440.032
negative regulation of cell cycleGO:00457861930.032
regulation of cell cycle processGO:00105642660.032
cell part morphogenesisGO:00329901370.032
regulation of cell cycleGO:00517263930.032
g protein coupled receptor signaling pathwayGO:00071862070.032
regenerationGO:003109940.032
positive regulation of nucleoside metabolic processGO:00459791860.031
regulation of cell growthGO:00015581350.031
circulatory system developmentGO:00723592620.031
cellular protein catabolic processGO:00442572610.031
regulation of protein localizationGO:00328802960.031
cellular response to growth factor stimulusGO:00713631970.031
actin filament based processGO:00300292240.031
astrocyte differentiationGO:004870840.030
regulation of protein kinase activityGO:00458592890.030
cellular macromolecular complex assemblyGO:00346223240.030
muscle contractionGO:0006936730.030
regulation of growthGO:00400081650.030
regulation of kinase activityGO:00435493140.030
regulation of transferase activityGO:00513383550.030
lipid biosynthetic processGO:00086101770.030
positive regulation of ras gtpase activityGO:00323201170.030
cardiac muscle cell contractionGO:008600340.030
regulation of cell projection organizationGO:00313441070.029
determination of adult lifespanGO:000834020.029
transmission of nerve impulseGO:0019226110.029
post embryonic developmentGO:000979120.029
positive regulation of gtp catabolic processGO:00331261660.029
covalent chromatin modificationGO:00165692540.029
negative regulation of protein modification processGO:00314002000.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
response to nitrogen compoundGO:19016981840.029
biological adhesionGO:00226103310.029
positive regulation of programmed cell deathGO:00430682490.029
nerve developmentGO:002167540.029
behaviorGO:00076101120.029
protein maturationGO:00516042330.028
second messenger mediated signalingGO:0019932780.028
cation transmembrane transportGO:00986552380.028
carbohydrate derivative biosynthetic processGO:19011372070.028
inorganic ion transmembrane transportGO:00986602310.028
negative regulation of cell differentiationGO:00455961710.028
positive regulation of protein kinase activityGO:00458601900.028
rho protein signal transductionGO:0007266260.028
nucleotide biosynthetic processGO:00091651090.027
hindbrain developmentGO:003090230.027
monovalent inorganic cation transportGO:00156721280.027
apoptotic signaling pathwayGO:00971902680.027
negative regulation of cell proliferationGO:00082852280.026
negative regulation of cell deathGO:00605483450.026
regulation of protein transportGO:00512232130.026
metal ion transportGO:00300012720.026
peripheral nervous system developmentGO:000742220.026
regulation of protein catabolic processGO:00421761550.026
negative regulation of organelle organizationGO:00106391260.026
multicellular organismal agingGO:001025930.025
ameboidal type cell migrationGO:00016671350.025
negative regulation of catalytic activityGO:00430863350.025
cellular homeostasisGO:00197251960.025
positive regulation of synaptic transmissionGO:005080640.025
positive regulation of protein phosphorylationGO:00019343130.025
taxisGO:00423301570.025
regulation of cell adhesionGO:00301551660.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
regulation of gtpase activityGO:00430871800.025
organ formationGO:004864530.025
neural crest cell developmentGO:001403230.025
cytokine productionGO:00018162470.024
regulation of establishment of protein localizationGO:00702012420.024
cellular protein complex assemblyGO:00436231880.024
immune responseGO:00069553070.024
sodium ion transmembrane transportGO:0035725590.024
regulation of proteolysisGO:00301622930.024
metencephalon developmentGO:002203720.024
regulation of apoptotic signaling pathwayGO:20012331750.023
vasculature developmentGO:00019441810.023
tissue regenerationGO:004224630.023
nitrogen compound transportGO:00717051910.023
glial cell migrationGO:000834740.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
regulation of ras gtpase activityGO:00323181280.023
regulation of cytokine productionGO:00018172320.023
protein ubiquitinationGO:00165673140.023
signal transduction by phosphorylationGO:00230142970.023
cell growthGO:00160491600.022
mapk cascadeGO:00001652880.022
exocytosisGO:0006887710.022
signal releaseGO:0023061700.022
positive regulation of organelle organizationGO:00106381950.022
action potentialGO:0001508340.022
regulation of protein modification by small protein conjugation or removalGO:19033201070.022
small molecule biosynthetic processGO:00442831570.022
negative regulation of catabolic processGO:00098951040.022
hormone secretionGO:0046879650.022
single organism cell adhesionGO:00986021790.022
hormone transportGO:0009914680.022
regulation of neuronal synaptic plasticityGO:004816810.022
nucleoside phosphate biosynthetic processGO:19012931090.022
cardiovascular system developmentGO:00723582620.022
posttranscriptional regulation of gene expressionGO:00106082130.022
neuron projection morphogenesisGO:0048812500.022
positive regulation of gtpase activityGO:00435471660.022
visual behaviorGO:000763220.022
oxidation reduction processGO:00551143960.022
mitotic cell cycleGO:00002783260.021
positive regulation of cell motilityGO:20001471770.021
negative regulation of cellular amine metabolic processGO:003323930.021
positive regulation of transferase activityGO:00513472270.021
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.021
negative regulation of intracellular signal transductionGO:19025321830.021
cranial nerve developmentGO:002154540.021
modification dependent macromolecule catabolic processGO:00436322120.021
endosomal transportGO:00161971290.021
somatic muscle developmentGO:000752510.020
axonogenesisGO:0007409310.020
chromatin modificationGO:00165682980.020
blood vessel morphogenesisGO:00485141620.020
segmentationGO:003528240.020
rhythmic behaviorGO:000762220.020
negative regulation of phosphorus metabolic processGO:00105632670.020
negative regulation of transportGO:00510511760.020
monocarboxylic acid metabolic processGO:00327871850.020
negative regulation of hydrolase activityGO:00513461820.020
activation of protein kinase activityGO:0032147900.020
actin filament based movementGO:0030048170.020
leukocyte activationGO:00453211640.020
regulation of cell divisionGO:00513021160.019
negative regulation of cell cycle processGO:00109481210.019
negative regulation of phosphorylationGO:00423261740.019
negative regulation of proteolysisGO:00458611320.019
muscle system processGO:0003012810.019
proteasomal protein catabolic processGO:00104981760.019
histone modificationGO:00165702510.019
negative regulation of apoptotic processGO:00430663160.019
spinal cord developmentGO:002151040.019
response to metal ionGO:0010038840.019
modification dependent protein catabolic processGO:00199412090.019
neuroblast proliferationGO:000740540.019
regulation of organelle transport along microtubuleGO:190251320.019
positive regulation of proteolysisGO:00458621420.019
motor neuron axon guidanceGO:000804520.018
cellular ion homeostasisGO:00068731680.018
regulation of muscle contractionGO:0006937450.018
negative regulation of programmed cell deathGO:00430693210.018
amide transportGO:0042886760.018
positive regulation of nucleotide catabolic processGO:00308131850.018
positive regulation of axon extensionGO:004577340.018
response to other organismGO:00517072610.018
negative regulation of protein processingGO:00109551420.018
negative regulation of phosphate metabolic processGO:00459362670.018
response to radiationGO:00093141510.018
response to growth factorGO:00708482050.018
synaptic transmissionGO:0007268610.018
cellular response to nitrogen compoundGO:19016991440.018
fatty acid metabolic processGO:00066311150.018
response to hormoneGO:00097251750.018
regulation of i kappab kinase nf kappab signalingGO:00431221620.018
cellular response to cytokine stimulusGO:00713451810.018
striated muscle contractionGO:0006941520.018
circadian behaviorGO:004851220.018
response to woundingGO:00096111680.018
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.018
defense responseGO:00069523150.018
intermediate filament cytoskeleton organizationGO:0045104170.018
blood vessel developmentGO:00015681720.018
response to cytokineGO:00340972320.018
regulation of cellular protein catabolic processGO:1903362960.017
cyclic nucleotide metabolic processGO:0009187820.017
anion transportGO:00068201610.017
cellular chemical homeostasisGO:00550821800.017
cellular response to organic cyclic compoundGO:00714071270.017
chemotaxisGO:00069351570.017
regulation of protein maturationGO:19033171500.017
cation homeostasisGO:00550801890.017
chromatin organizationGO:00063253510.017
epithelium migrationGO:00901321190.017
hippocampus developmentGO:002176610.017
protein homooligomerizationGO:00512601000.017
intracellular protein transportGO:00068862700.017
cellular metal ion homeostasisGO:00068751460.017
positive regulation of cytokine productionGO:00018191670.017
metal ion homeostasisGO:00550651690.017
divalent inorganic cation homeostasisGO:00725071360.017
actin mediated cell contractionGO:0070252120.017
reactive oxygen species biosynthetic processGO:190340940.017
inner ear morphogenesisGO:004247240.017
mesenchymal cell developmentGO:0014031500.017
positive regulation of secretionGO:00510471160.017
regulation of protein serine threonine kinase activityGO:00719001790.017
positive regulation of neurogenesisGO:0050769490.017
ion homeostasisGO:00508012300.017
syncytium formation by plasma membrane fusionGO:000076820.016
regulation of system processGO:00440571010.016
female gamete generationGO:000729220.016
reactive oxygen species metabolic processGO:0072593750.016
angiogenesisGO:00015251470.016
cell divisionGO:00513011680.016
blood circulationGO:00080151130.016
matingGO:000761810.016
cellular cation homeostasisGO:00300031630.016
specification of organ identityGO:001009230.016
regulation of protein processingGO:00706131500.016
positive regulation of nervous system developmentGO:0051962540.016
cell cycle checkpointGO:00000751170.016
cellular response to lipidGO:00713961270.016
sodium ion transportGO:0006814610.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
establishment of protein localization to organelleGO:00725941720.016
nucleocytoplasmic transportGO:00069131760.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
negative regulation of cell migrationGO:00303361020.016
innate immune responseGO:00450871780.016
regulation of cytoplasmic transportGO:19036491490.016
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.016
cerebellum developmentGO:002154920.016
regulation of transmembrane transportGO:00347621390.016
reactive nitrogen species metabolic processGO:200105730.016
purine nucleotide biosynthetic processGO:0006164840.016
maintenance of locationGO:00512351120.016
neural nucleus developmentGO:0048857470.016
positive regulation of cellular component biogenesisGO:00440891580.016
ubiquitin dependent protein catabolic processGO:00065112060.016
adult locomotory behaviorGO:000834410.015
peptide secretionGO:0002790510.015
regulation of proteasomal protein catabolic processGO:0061136870.015
cellular response to organonitrogen compoundGO:00714171240.015
regulation of cytoskeleton organizationGO:00514931770.015
nucleoside monophosphate metabolic processGO:00091231910.015
canonical wnt signaling pathwayGO:00600701160.015
positive regulation of secretion by cellGO:19035321080.015
positive regulation of gliogenesisGO:001401540.015
midbrain developmentGO:0030901450.015
protein localization to nucleusGO:00345041360.015
anterior posterior axis specificationGO:000994820.015
cardiac muscle contractionGO:0060048340.015
positive regulation of immune responseGO:00507781590.015
ossificationGO:00015031210.015
anterior posterior axis specification embryoGO:000859520.015
cell substrate adhesionGO:00315891320.015
startle responseGO:000196430.015
negative regulation of protein maturationGO:19033181420.015
microtubule based transportGO:0010970210.015
purine containing compound biosynthetic processGO:0072522880.015
rna processingGO:00063962550.015
regulation of protein complex assemblyGO:00432541470.015
mitotic cell cycle phase transitionGO:00447721620.015
dna repairGO:00062811980.015
i kappab kinase nf kappab signalingGO:00072491660.015
positive regulation of kinase activityGO:00336742040.015
regulation of defense responseGO:00313471540.015
positive regulation of locomotionGO:00400171860.015
heart processGO:0003015620.015
protein targetingGO:00066051870.015
axon developmentGO:0061564340.015
skeletal system developmentGO:0001501790.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
nuclear transportGO:00511691790.015
negative regulation of cellular catabolic processGO:0031330830.015
rna splicingGO:00083801310.015
substantia nigra developmentGO:0021762450.015
peptidyl tyrosine phosphorylationGO:00181081700.014
response to bacteriumGO:00096171440.014
wnt signaling pathwayGO:00160551560.014
negative regulation of growthGO:0045926970.014
negative regulation of secretion by cellGO:1903531520.014
regulation of dna metabolic processGO:00510521530.014
lymphocyte activationGO:00466491330.014
regulation of response to external stimulusGO:00321012220.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.014
response to nutrient levelsGO:0031667810.014
synaptic vesicle exocytosisGO:001607930.014
regulation of immune responseGO:00507762010.014
peptide hormone secretionGO:0030072500.014
tissue migrationGO:00901301190.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
response to axon injuryGO:004867810.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
regulation of vesicle mediated transportGO:00606271300.014
regulation of lipid metabolic processGO:0019216960.014
regulation of neural precursor cell proliferationGO:200017740.014
positive regulation of intracellular transportGO:00323881040.014
blastoderm segmentationGO:000735020.014
negative regulation of cellular component movementGO:00512711060.014
epithelium developmentGO:00604292270.014
oogenesisGO:004847720.014
visual learningGO:000854210.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
retrograde transport endosome to golgiGO:0042147450.014
positive regulation of cell adhesionGO:0045785840.014
multi organism cellular processGO:00447641560.014
long term memoryGO:000761620.014
positive regulation of camp metabolic processGO:0030816410.014
central nervous system neuron axonogenesisGO:002195530.014
compound eye developmentGO:004874910.014
regulation of protein ubiquitinationGO:0031396950.014
regulation of camp metabolic processGO:0030814520.014
long term synaptic potentiationGO:006029110.014
oocyte differentiationGO:000999420.014
endomembrane system organizationGO:00102561960.013
protein acylationGO:00435431380.013
alcohol metabolic processGO:00060661140.013
positive regulation of mapk cascadeGO:00434101900.013
regulation of actin filament based processGO:00329701410.013
response to inorganic substanceGO:00100351270.013
receptor metabolic processGO:0043112810.013
mitotic cell cycle processGO:19030472860.013
peptide transportGO:0015833740.013
regulation of ion transmembrane transportGO:00347651320.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.013
response to drugGO:0042493810.013
oocyte developmentGO:004859910.013
carbohydrate metabolic processGO:00059752070.013
negative regulation of neurogenesisGO:0050768260.013
regulation of jnk cascadeGO:0046328730.013
positive regulation of apoptotic signaling pathwayGO:2001235700.013
intermediate filament based processGO:0045103170.013
potassium ion transportGO:0006813620.013
circulatory system processGO:00030131130.013
establishment of protein localization to membraneGO:00901501210.013
negative regulation of secretionGO:0051048580.013
cellular response to abiotic stimulusGO:00712141170.013
regulation of synaptic vesicle transportGO:190280330.013
cell cycle phase transitionGO:00447701730.013
organ morphogenesisGO:00098871470.013

NEFL disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.031
nervous system diseaseDOID:8634310.030
sensory system diseaseDOID:00501552030.030
organ system cancerDOID:00506861640.029
disease of cellular proliferationDOID:145661740.029
cancerDOID:1621670.029
central nervous system diseaseDOID:3311860.027
inherited metabolic disorderDOID:6552420.013