Homo sapiens

63 known processes

NEFH

neurofilament, heavy polypeptide

(Aliases: NFH)

NEFH biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.093
amine metabolic processGO:0009308440.073
post embryonic developmentGO:000979120.072
regulation of cellular amino acid metabolic processGO:000652160.070
cellular amine metabolic processGO:0044106410.068
system processGO:00030083490.068
regulation of cellular amine metabolic processGO:0033238110.068
regulation of cellular ketone metabolic processGO:0010565500.065
cellular ketone metabolic processGO:0042180800.063
transmembrane transportGO:00550853990.059
locomotory behaviorGO:000762610.059
positive regulation of transportGO:00510503360.057
positive regulation of cellular amino acid metabolic processGO:004576430.052
nervous system developmentGO:00073992930.050
positive regulation of cellular amine metabolic processGO:003324070.050
ion transmembrane transportGO:00342203380.048
cation transportGO:00068123310.047
cation transmembrane transportGO:00986552380.045
lipid metabolic processGO:00066293810.044
cellular lipid metabolic processGO:00442553030.043
regulation of cellular component movementGO:00512703340.042
multicellular organismal agingGO:001025930.042
inorganic cation transmembrane transportGO:00986621940.042
secretionGO:00469032540.042
purine ribonucleoside metabolic processGO:00461284370.041
inorganic ion transmembrane transportGO:00986602310.041
determination of adult lifespanGO:000834020.040
ion homeostasisGO:00508012300.040
organophosphate catabolic processGO:00464344300.040
ribonucleoside triphosphate catabolic processGO:00092033910.040
positive regulation of phosphorylationGO:00423273940.039
ras protein signal transductionGO:0007265730.039
negative regulation of protein metabolic processGO:00512483910.038
regulation of secretionGO:00510461940.038
regulation of locomotionGO:00400123290.038
cell developmentGO:00484683280.038
chemical homeostasisGO:00488783060.038
nucleoside phosphate catabolic processGO:19012924120.038
purine containing compound catabolic processGO:00725234110.037
ribonucleoside catabolic processGO:00424544060.037
neuromuscular junction developmentGO:000752830.037
response to oxygen containing compoundGO:19017003690.037
positive regulation of cellular component organizationGO:00511303760.037
negative regulation of cellular protein metabolic processGO:00322693530.037
ribonucleoside triphosphate metabolic processGO:00091994120.036
negative regulation of catalytic activityGO:00430863350.036
regulation of transferase activityGO:00513383550.036
purine nucleoside catabolic processGO:00061523980.036
cytoplasmic transportGO:00164823790.036
purine ribonucleoside catabolic processGO:00461303980.035
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
nucleoside triphosphate metabolic processGO:00091414220.035
purine nucleoside triphosphate metabolic processGO:00091444120.035
neurotransmitter secretionGO:000726940.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.035
oogenesisGO:004847720.035
negative regulation of phosphate metabolic processGO:00459362670.035
purine ribonucleotide catabolic processGO:00091544040.035
hindbrain developmentGO:003090230.034
secretion by cellGO:00329402260.034
cell morphogenesisGO:00009022960.034
Mouse
cellular component morphogenesisGO:00329893140.034
Mouse
purine nucleotide catabolic processGO:00061954050.034
vesicle mediated transportGO:00161923710.034
ribonucleotide catabolic processGO:00092614050.034
small gtpase mediated signal transductionGO:0007264780.034
nucleoside catabolic processGO:00091644080.034
glycosyl compound catabolic processGO:19016584130.034
regulation of kinase activityGO:00435493140.034
negative regulation of multicellular organismal processGO:00512413170.033
negative regulation of phosphorus metabolic processGO:00105632670.033
nucleotide catabolic processGO:00091664080.033
regulation of secretion by cellGO:19035301770.033
positive regulation of hydrolase activityGO:00513453310.033
regulation of cell migrationGO:00303342890.033
female gamete generationGO:000729220.033
nucleoside triphosphate catabolic processGO:00091433940.032
single organism cellular localizationGO:19025803320.032
cardiac muscle cell contractionGO:008600340.032
positive regulation of synaptic transmissionGO:005080640.032
small molecule biosynthetic processGO:00442831570.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
actin filament based processGO:00300292240.032
neurological system processGO:00508771630.031
response to abiotic stimulusGO:00096283360.031
regulation of cell differentiationGO:00455953930.031
single organism membrane organizationGO:00448022680.031
regulation of protein kinase activityGO:00458592890.031
regulation of ion transportGO:00432691890.031
cellular response to endogenous stimulusGO:00714953360.031
adult locomotory behaviorGO:000834410.031
memoryGO:000761330.031
metal ion transportGO:00300012720.031
lipid biosynthetic processGO:00086101770.030
segmentationGO:003528240.030
positive regulation of catabolic processGO:00098963100.029
regulation of neurotransmitter secretionGO:004692830.029
regenerationGO:003109940.029
cellular response to oxygen containing compoundGO:19017012760.028
negative regulation of cellular component organizationGO:00511292350.028
immune responseGO:00069553070.028
rho protein signal transductionGO:0007266260.028
signal transduction by phosphorylationGO:00230142970.028
guanosine containing compound metabolic processGO:19010682440.028
regulation of cellular component biogenesisGO:00440872810.028
regulation of cell cycleGO:00517263930.028
regulation of cell motilityGO:20001452990.028
organonitrogen compound biosynthetic processGO:19015662000.028
positive regulation of protein phosphorylationGO:00019343130.027
membrane organizationGO:00610242920.027
spinal cord developmentGO:002151040.027
regulation of proteolysisGO:00301622930.027
protein localization to organelleGO:00333652800.027
regulation of synaptic plasticityGO:004816730.027
negative regulation of cell proliferationGO:00082852280.027
mitotic cell cycleGO:00002783260.026
cell projection organizationGO:00300302520.026
metal ion homeostasisGO:00550651690.026
monocarboxylic acid metabolic processGO:00327871850.026
cellular macromolecule catabolic processGO:00442653800.026
cation homeostasisGO:00550801890.026
generation of neuronsGO:00486991520.026
oxidation reduction processGO:00551143960.025
positive regulation of cellular catabolic processGO:00313312840.025
mapk cascadeGO:00001652880.025
negative regulation of cellular amine metabolic processGO:003323930.025
regulation of protein localizationGO:00328802960.025
biological adhesionGO:00226103310.025
neurogenesisGO:00220081690.025
carbohydrate derivative biosynthetic processGO:19011372070.025
cell adhesionGO:00071553250.025
positive regulation of cell deathGO:00109422630.025
morphogenesis of embryonic epitheliumGO:001633140.025
intracellular protein transportGO:00068862700.025
divalent inorganic cation homeostasisGO:00725071360.025
cellular homeostasisGO:00197251960.025
regulation of establishment of protein localizationGO:00702012420.025
regulation of nucleotide metabolic processGO:00061402690.024
negative regulation of cell deathGO:00605483450.024
g protein coupled receptor signaling pathwayGO:00071862070.024
positive regulation of programmed cell deathGO:00430682490.024
regulation of hormone levelsGO:00108171250.024
associative learningGO:000830610.024
positive regulation of transferase activityGO:00513472270.024
cell cell signalingGO:00072671550.024
metencephalon developmentGO:002203720.024
regulation of anatomical structure morphogenesisGO:00226032860.024
response to organic cyclic compoundGO:00140702040.024
regulation of response to external stimulusGO:00321012220.023
gtp metabolic processGO:00460392390.023
neuron differentiationGO:00301821380.023
regulation of protein transportGO:00512232130.023
cellular macromolecular complex assemblyGO:00346223240.023
protein catabolic processGO:00301633250.023
negative regulation of cellular amino acid metabolic processGO:004576320.023
apoptotic signaling pathwayGO:00971902680.023
negative regulation of programmed cell deathGO:00430693210.023
cardiovascular system developmentGO:00723582620.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
muscle contractionGO:0006936730.023
dephosphorylationGO:00163112090.023
regulation of mapk cascadeGO:00434082620.023
negative regulation of apoptotic processGO:00430663160.023
defense responseGO:00069523150.023
negative regulation of developmental processGO:00510932470.023
regulation of cell cycle processGO:00105642660.023
organic acid biosynthetic processGO:0016053970.022
guanosine containing compound catabolic processGO:19010692390.022
nitrogen compound transportGO:00717051910.022
carboxylic acid biosynthetic processGO:0046394970.022
protein maturationGO:00516042330.022
negative regulation of protein modification processGO:00314002000.022
regulation of intracellular transportGO:00323861950.022
regulation of purine nucleotide metabolic processGO:19005422640.022
carbohydrate metabolic processGO:00059752070.022
cytokine productionGO:00018162470.022
chromatin organizationGO:00063253510.022
response to nitrogen compoundGO:19016981840.021
cellular metal ion homeostasisGO:00068751460.021
cellular response to dna damage stimulusGO:00069743790.021
positive regulation of secretionGO:00510471160.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
regulation of vesicle mediated transportGO:00606271300.021
cellular ion homeostasisGO:00068731680.021
negative regulation of transportGO:00510511760.021
regulation of membrane potentialGO:0042391950.021
negative regulation of intracellular signal transductionGO:19025321830.021
cerebellum developmentGO:002154920.021
protein processingGO:00164852260.021
cellular chemical homeostasisGO:00550821800.021
cellular cation homeostasisGO:00300031630.021
positive regulation of apoptotic processGO:00430652460.021
matingGO:000761810.021
positive regulation of cell proliferationGO:00082843010.021
reactive nitrogen species metabolic processGO:200105730.021
reactive oxygen species biosynthetic processGO:190340940.020
positive regulation of protein kinase activityGO:00458601900.020
regulation of system processGO:00440571010.020
regulation of purine nucleotide catabolic processGO:00331212050.020
gtp catabolic processGO:00061842370.020
negative regulation of hydrolase activityGO:00513461820.020
monovalent inorganic cation transportGO:00156721280.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
response to lipidGO:00339932060.020
nerve developmentGO:002167540.020
negative regulation of phosphorylationGO:00423261740.020
single organism carbohydrate metabolic processGO:00447231930.020
growthGO:00400072020.020
regulation of nucleotide catabolic processGO:00308112050.020
regulation of transmembrane transportGO:00347621390.020
blastoderm segmentationGO:000735020.020
oocyte differentiationGO:000999420.020
actin filament based movementGO:0030048170.020
protein targetingGO:00066051870.020
positive regulation of organelle organizationGO:00106381950.020
anterior posterior axis specificationGO:000994820.020
mitotic cell cycle processGO:19030472860.020
positive regulation of mapk cascadeGO:00434101900.019
response to hormoneGO:00097251750.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
muscle system processGO:0003012810.019
regulation of nucleoside metabolic processGO:00091182090.019
organic hydroxy compound metabolic processGO:19016151470.019
regulation of protein serine threonine kinase activityGO:00719001790.019
reactive oxygen species metabolic processGO:0072593750.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
maintenance of locationGO:00512351120.019
organophosphate biosynthetic processGO:00904071630.019
anion transportGO:00068201610.019
calcium ion homeostasisGO:00550741220.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
protein oligomerizationGO:00512591730.019
regulation of cellular response to stressGO:00801352440.019
positive regulation of cell differentiationGO:00455972110.019
rhythmic behaviorGO:000762220.019
response to external biotic stimulusGO:00432072610.019
oocyte developmentGO:004859910.019
epithelium developmentGO:00604292270.019
organ formationGO:004864530.019
cellular divalent inorganic cation homeostasisGO:00725031280.019
regulation of reactive oxygen species biosynthetic processGO:190342630.019
regulation of metal ion transportGO:00109591200.019
microtubule based processGO:00070172100.019
positive regulation of developmental processGO:00510943140.019
embryonic epithelial tube formationGO:000183840.019
neuron projection developmentGO:00311751060.018
divalent inorganic cation transportGO:00725111580.018
spermatid differentiationGO:004851540.018
protein modification by small protein conjugationGO:00324463420.018
divalent metal ion transportGO:00708381520.018
positive regulation of nucleotide metabolic processGO:00459812300.018
cellular protein catabolic processGO:00442572610.018
endomembrane system organizationGO:00102561960.018
circulatory system developmentGO:00723592620.018
regulation of ion transmembrane transportGO:00347651320.018
behaviorGO:00076101120.018
chromatin modificationGO:00165682980.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
positive regulation of kinase activityGO:00336742040.018
inner ear morphogenesisGO:004247240.018
circadian behaviorGO:004851220.018
blood circulationGO:00080151130.018
regulation of cytoskeleton organizationGO:00514931770.018
cell fate determinationGO:000170930.018
positive regulation of ion transportGO:0043270870.018
negative regulation of protein phosphorylationGO:00019331400.018
compound eye developmentGO:004874910.018
response to cytokineGO:00340972320.018
positive regulation of immune system processGO:00026842830.018
histone modificationGO:00165702510.018
regulation of cell developmentGO:00602841610.018
establishment of protein localization to organelleGO:00725941720.018
positive regulation of cytokine productionGO:00018191670.018
regulation of cell morphogenesisGO:00226041530.017
peptidyl tyrosine modificationGO:00182121700.017
cellular response to organic cyclic compoundGO:00714071270.017
actin mediated cell contractionGO:0070252120.017
neuron developmentGO:00486661130.017
calcium ion transportGO:00068161470.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
innate immune responseGO:00450871780.017
cellular response to cytokine stimulusGO:00713451810.017
multicellular organismal response to stressGO:003355510.017
spermatid developmentGO:000728640.017
cell part morphogenesisGO:00329901370.017
Mouse
axon cargo transportGO:000808820.017
sensory perception of painGO:001923340.017
immune system developmentGO:00025201950.017
neuroblast proliferationGO:000740540.017
regulation of ras protein signal transductionGO:00465781550.017
positive regulation of nucleoside metabolic processGO:00459791860.017
positive regulation of nucleotide catabolic processGO:00308131850.017
motor neuron axon guidanceGO:000804520.017
posttranscriptional regulation of gene expressionGO:00106082130.017
regulation of peptidase activityGO:00525471800.017
cell divisionGO:00513011680.017
positive regulation of secretion by cellGO:19035321080.017
morphogenesis of a polarized epitheliumGO:000173830.017
striated muscle contractionGO:0006941520.017
cardiac muscle contractionGO:0060048340.017
sensory perceptionGO:00076001030.017
actin cytoskeleton organizationGO:00300362070.017
cell morphogenesis involved in differentiationGO:00009041440.017
Mouse
positive regulation of cellular component biogenesisGO:00440891580.017
regulation of endopeptidase activityGO:00525481700.017
anterior posterior axis specification embryoGO:000859520.017
negative regulation of cell differentiationGO:00455961710.016
regulation of neural precursor cell proliferationGO:200017740.016
protein localization to membraneGO:00726571600.016
peripheral nervous system developmentGO:000742220.016
Mouse
tripartite regional subdivisionGO:000735120.016
response to organonitrogen compoundGO:00102431560.016
covalent chromatin modificationGO:00165692540.016
calcium ion transmembrane transportGO:0070588760.016
regulation of cytokine productionGO:00018172320.016
central nervous system developmentGO:00074171230.016
Human
purine nucleoside monophosphate metabolic processGO:00091261860.016
forebrain regionalizationGO:002187130.016
regulation of gtp catabolic processGO:00331241800.016
forebrain generation of neuronsGO:002187230.016
glycoprotein metabolic processGO:00091001100.016
protein ubiquitinationGO:00165673140.016
regulation of gtpase activityGO:00430871800.016
photoreceptor cell differentiationGO:004653020.016
atp metabolic processGO:00460341760.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
cellular calcium ion homeostasisGO:00068741170.016
cellular protein complex assemblyGO:00436231880.016
cellular response to nitrogen compoundGO:19016991440.016
limbic system developmentGO:002176130.016
positive regulation of gtp catabolic processGO:00331261660.016
nucleocytoplasmic transportGO:00069131760.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
positive regulation of cellular component movementGO:00512721810.016
nucleoside monophosphate metabolic processGO:00091231910.016
regulation of apoptotic signaling pathwayGO:20012331750.016
cell growthGO:00160491600.016
regulation of homeostatic processGO:00328441210.016
negative regulation of cell cycleGO:00457861930.016
response to other organismGO:00517072610.016
response to axon injuryGO:004867810.016
sex determinationGO:000753030.015
regulation of transporter activityGO:0032409820.015
regulation of mitotic cell cycleGO:00073461890.015
single organism cell adhesionGO:00986021790.015
regulation of protein maturationGO:19033171500.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
fatty acid metabolic processGO:00066311150.015
response to biotic stimulusGO:00096072760.015
modification dependent macromolecule catabolic processGO:00436322120.015
positive regulation of cell motilityGO:20001471770.015
modification dependent protein catabolic processGO:00199412090.015
monocarboxylic acid biosynthetic processGO:0072330670.015
nucleoside phosphate biosynthetic processGO:19012931090.015
nuclear transportGO:00511691790.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
long term memoryGO:000761620.015
alcohol metabolic processGO:00060661140.015
tissue regenerationGO:004224630.015
positive regulation of gtpase activityGO:00435471660.015
glial cell migrationGO:000834740.015
ubiquitin dependent protein catabolic processGO:00065112060.015
sequestering of metal ionGO:0051238240.015
regulation of meiotic cell cycleGO:005144540.015
regulation of multi organism processGO:00439001570.015
vasculature developmentGO:00019441810.015
regulation of protein catabolic processGO:00421761550.015
head developmentGO:00603221080.015
Human
positive regulation of proteolysisGO:00458621420.015
somitogenesisGO:000175620.015
rna processingGO:00063962550.015
organelle assemblyGO:00709251760.014
stem cell divisionGO:001714520.014
sequestering of calcium ionGO:0051208170.014
organic anion transportGO:00157111030.014
cell cycle phase transitionGO:00447701730.014
specification of organ identityGO:001009230.014
neuron fate commitmentGO:004866320.014
regulation of neuronal synaptic plasticityGO:004816810.014
regulation of cytoplasmic transportGO:19036491490.014
syncytium formation by plasma membrane fusionGO:000076820.014
regulation of protein complex assemblyGO:00432541470.014
sodium ion transmembrane transportGO:0035725590.014
hemopoiesisGO:00300971800.014
endocytosisGO:00068971590.014
proteasomal protein catabolic processGO:00104981760.014
negative regulation of organelle organizationGO:00106391260.014
regulation of ion transmembrane transporter activityGO:0032412720.014
regulation of protein processingGO:00706131500.014
peptidyl tyrosine phosphorylationGO:00181081700.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
second messenger mediated signalingGO:0019932780.014
neurofilament cytoskeleton organizationGO:006005220.014
nucleoside monophosphate catabolic processGO:00091251590.014
response to fungusGO:000962040.014
cell activationGO:00017752130.014
regulation of immune responseGO:00507762010.014
negative regulation of protein processingGO:00109551420.014
regulation of growthGO:00400081650.014
thymus developmentGO:004853830.014
neural tube formationGO:000184130.014
somatic stem cell divisionGO:004810310.014
neural crest cell developmentGO:001403230.014
cytosolic calcium ion homeostasisGO:0051480890.014
protein autophosphorylationGO:00467771230.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
response to radiationGO:00093141510.014
ventral spinal cord developmentGO:002151710.014
negative regulation of synaptic transmissionGO:005080520.014
small molecule catabolic processGO:0044282920.014
circulatory system processGO:00030131130.014
microtubule cytoskeleton organizationGO:00002261760.014
Mouse
forelimb morphogenesisGO:003513640.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
brain developmentGO:0007420970.014
Human
mitochondrion organizationGO:00070051560.014
negative regulation of protein maturationGO:19033181420.014
synaptic vesicle endocytosisGO:004848820.014
cranial nerve developmentGO:002154540.014
cellular response to growth factor stimulusGO:00713631970.014
positive regulation of cell migrationGO:00303351720.014
cell type specific apoptotic processGO:00972851250.014
neuron projection regenerationGO:003110210.014
response to growth factorGO:00708482050.014
peptidyl serine modificationGO:00182091060.014
nucleotide biosynthetic processGO:00091651090.013
positive regulation of locomotionGO:00400171860.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
regulation of cell growthGO:00015581350.013
regulation of transmembrane transporter activityGO:0022898740.013
visual behaviorGO:000763220.013
lipid transportGO:0006869900.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
establishment of planar polarityGO:000173630.013
regulation of cell adhesionGO:00301551660.013
positive regulation of protein transportGO:00512221350.013
copulationGO:000762010.013
glycerolipid metabolic processGO:00464861070.013
wnt signaling pathwayGO:00160551560.013
negative regulation of transferase activityGO:00513481240.013
interspecies interaction between organismsGO:00444191560.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
response to inorganic substanceGO:00100351270.013
regulation of dna metabolic processGO:00510521530.013
behavioral response to ethanolGO:004814920.013
sleepGO:003043120.013
lung alveolus developmentGO:004828640.013
i kappab kinase nf kappab signalingGO:00072491660.013
regulation of protein secretionGO:0050708860.013
primary neural tube formationGO:001402030.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
response to woundingGO:00096111680.013
cell projection morphogenesisGO:00488581290.013
Mouse
regulation of actin filament based processGO:00329701410.013
purine nucleotide biosynthetic processGO:0006164840.013
positive regulation of ras gtpase activityGO:00323201170.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
negative regulation of proteolysisGO:00458611320.013
negative regulation of locomotionGO:00400131180.013
peptidyl serine phosphorylationGO:00181051010.013
salivary gland morphogenesisGO:000743540.013
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.013
synaptic vesicle recyclingGO:003646530.013
atp catabolic processGO:00062001570.013
positive regulation of cytosolic calcium ion concentrationGO:0007204820.013
rna interferenceGO:001624640.013
mitotic cell cycle phase transitionGO:00447721620.013
cell differentiation in spinal cordGO:002151510.013
ameboidal type cell migrationGO:00016671350.013
axon regenerationGO:003110310.013

NEFH disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.034
Human
nervous system diseaseDOID:8634310.034
Human
disease of metabolismDOID:00146672950.033
musculoskeletal system diseaseDOID:172230.029
Human
inherited metabolic disorderDOID:6552420.028
sensory system diseaseDOID:00501552030.026
disease of cellular proliferationDOID:145661740.022
connective tissue diseaseDOID:651090.020
cancerDOID:1621670.020
organ system cancerDOID:00506861640.019
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
neurodegenerative diseaseDOID:12891020.017
Human
bone diseaseDOID:0080001880.017
brain diseaseDOID:936730.016
Human
immune system diseaseDOID:29141550.015
myopathyDOID:4231040.013
Human
muscular diseaseDOID:00800001140.013
Human
muscle tissue diseaseDOID:661130.013
Human
cardiovascular system diseaseDOID:12871060.013
Human
retinal diseaseDOID:56791180.013
disease of mental healthDOID:150700.013