Homo sapiens

28 known processes

PSENEN

presenilin enhancer 2 homolog (C. elegans)

(Aliases: MSTP064,PEN-2,PEN2)

PSENEN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
notch receptor processingGO:000722020.224
Mouse
post embryonic developmentGO:000979120.139
protein maturationGO:00516042330.123
amine metabolic processGO:0009308440.117
membrane protein proteolysisGO:0033619380.117
amyloid precursor protein catabolic processGO:0042987120.093
cell activationGO:00017752130.080
leukocyte proliferationGO:0070661740.079
protein processingGO:00164852260.075
membrane lipid metabolic processGO:0006643530.059
lymphocyte proliferationGO:0046651700.057
determination of adult lifespanGO:000834020.054
lymphocyte activationGO:00466491330.053
positive regulation of immune system processGO:00026842830.053
cytoplasmic transportGO:00164823790.052
vacuole organizationGO:0007033440.050
cellular ketone metabolic processGO:0042180800.047
establishment of viral latencyGO:001904310.046
regulation of cellular amino acid metabolic processGO:000652160.045
cellular chemical homeostasisGO:00550821800.045
exocytosisGO:0006887710.044
protein localization to organelleGO:00333652800.042
secretionGO:00469032540.041
regulation of cellular amine metabolic processGO:0033238110.040
calcium ion transportGO:00068161470.040
chemical homeostasisGO:00488783060.039
multicellular organismal agingGO:001025930.039
peptide metabolic processGO:0006518510.037
purine ribonucleoside metabolic processGO:00461284370.037
positive regulation of transportGO:00510503360.036
cellular macromolecular complex assemblyGO:00346223240.036
neuromuscular junction developmentGO:000752830.033
negative regulation of cellular amine metabolic processGO:003323930.033
cellular amine metabolic processGO:0044106410.033
regulation of cellular ketone metabolic processGO:0010565500.032
negative regulation of catalytic activityGO:00430863350.031
positive regulation of hydrolase activityGO:00513453310.031
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
immune responseGO:00069553070.030
glycosylationGO:0070085710.030
establishment of protein localization to organelleGO:00725941720.030
secretion by cellGO:00329402260.030
protein glycosylationGO:0006486620.029
myeloid cell homeostasisGO:0002262340.029
macromolecule glycosylationGO:0043413630.029
negative regulation of programmed cell deathGO:00430693210.028
response to external biotic stimulusGO:00432072610.027
cellular cation homeostasisGO:00300031630.027
carbohydrate derivative biosynthetic processGO:19011372070.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
regulation of vesicle mediated transportGO:00606271300.027
cation transportGO:00068123310.027
amyloid precursor protein metabolic processGO:0042982170.027
membrane protein ectodomain proteolysisGO:0006509330.026
leukocyte activationGO:00453211640.026
vesicle organizationGO:0016050620.026
reactive oxygen species metabolic processGO:0072593750.026
small molecule biosynthetic processGO:00442831570.026
cellular response to dna damage stimulusGO:00069743790.026
positive regulation of cellular catabolic processGO:00313312840.026
ion homeostasisGO:00508012300.026
peripheral nervous system developmentGO:000742220.026
viral processGO:00160321460.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
oogenesisGO:004847720.025
defense responseGO:00069523150.025
female gamete generationGO:000729220.025
carbohydrate metabolic processGO:00059752070.025
divalent inorganic cation transportGO:00725111580.025
cellular amide metabolic processGO:0043603690.024
regulation of cellular component movementGO:00512703340.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
purine ribonucleoside catabolic processGO:00461303980.024
leukocyte chemotaxisGO:0030595760.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
ras protein signal transductionGO:0007265730.023
cellular amino acid metabolic processGO:00065201160.023
regulation of calcium ion transportGO:0051924790.023
cellular ion homeostasisGO:00068731680.023
symbiosis encompassing mutualism through parasitismGO:00444031560.023
regulation of protein localizationGO:00328802960.023
intracellular protein transportGO:00068862700.022
purine containing compound catabolic processGO:00725234110.022
negative regulation of cell deathGO:00605483450.022
response to inorganic substanceGO:00100351270.021
divalent metal ion transportGO:00708381520.021
positive regulation of secretionGO:00510471160.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
synaptic vesicle exocytosisGO:001607930.021
negative regulation of cellular component organizationGO:00511292350.021
cellular lipid metabolic processGO:00442553030.021
cellular response to oxygen containing compoundGO:19017012760.021
positive regulation of cellular amine metabolic processGO:003324070.021
nucleoside catabolic processGO:00091644080.021
negative regulation of apoptotic processGO:00430663160.021
purine nucleotide catabolic processGO:00061954050.021
oocyte differentiationGO:000999420.020
negative regulation of axonogenesisGO:005077140.020
cilium organizationGO:0044782680.020
regulation of intracellular transportGO:00323861950.020
organophosphate catabolic processGO:00464344300.020
maintenance of locationGO:00512351120.020
sphingolipid metabolic processGO:0006665380.019
regulation of cell growthGO:00015581350.019
interspecies interaction between organismsGO:00444191560.018
mapk cascadeGO:00001652880.018
ubiquitin dependent protein catabolic processGO:00065112060.018
compound eye developmentGO:004874910.018
motor neuron axon guidanceGO:000804520.018
posttranscriptional regulation of gene expressionGO:00106082130.018
regulation of kinase activityGO:00435493140.018
response to biotic stimulusGO:00096072760.018
vesicle mediated transportGO:00161923710.018
t cell proliferationGO:0042098450.018
cellular macromolecule catabolic processGO:00442653800.018
regulation of establishment of protein localizationGO:00702012420.018
negative regulation of cellular protein metabolic processGO:00322693530.018
carboxylic acid biosynthetic processGO:0046394970.018
endosomal transportGO:00161971290.018
negative regulation of phosphorus metabolic processGO:00105632670.018
protein targetingGO:00066051870.018
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.018
response to other organismGO:00517072610.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
segmentationGO:003528240.017
lipid metabolic processGO:00066293810.017
single organism membrane organizationGO:00448022680.017
regenerationGO:003109940.017
cellular protein catabolic processGO:00442572610.017
transmembrane transportGO:00550853990.017
cellular homeostasisGO:00197251960.017
glycoprotein biosynthetic processGO:0009101910.017
positive regulation of kinase activityGO:00336742040.016
positive regulation of immune responseGO:00507781590.016
fatty acid elongation polyunsaturated fatty acidGO:003462640.016
regulation of protein kinase activityGO:00458592890.016
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152220.016
cation homeostasisGO:00550801890.016
positive regulation of calcium ion transportGO:0051928510.016
purine nucleoside triphosphate metabolic processGO:00091444120.016
establishment or maintenance of apical basal cell polarityGO:003508820.016
regulation of cell migrationGO:00303342890.016
purine nucleoside catabolic processGO:00061523980.015
ribonucleoside catabolic processGO:00424544060.015
oocyte developmentGO:004859910.015
glycoprotein metabolic processGO:00091001100.015
endocytosisGO:00068971590.015
circulatory system developmentGO:00723592620.015
regulation of cytoplasmic transportGO:19036491490.015
regulation of synaptic plasticityGO:004816730.015
regulation of protein complex assemblyGO:00432541470.015
signal transduction by phosphorylationGO:00230142970.015
positive regulation of cellular component movementGO:00512721810.015
cell morphogenesisGO:00009022960.015
reactive nitrogen species metabolic processGO:200105730.015
regulation of cellular response to stressGO:00801352440.015
positive regulation of cellular component organizationGO:00511303760.015
locomotory behaviorGO:000762610.015
single organism carbohydrate metabolic processGO:00447231930.015
nucleoside triphosphate metabolic processGO:00091414220.015
nucleoside triphosphate catabolic processGO:00091433940.014
positive regulation of secretion by cellGO:19035321080.014
negative regulation of protein metabolic processGO:00512483910.014
positive regulation of locomotionGO:00400171860.014
regulation of cell cycleGO:00517263930.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
positive regulation of cellular component biogenesisGO:00440891580.014
oxidation reduction processGO:00551143960.014
dna repairGO:00062811980.014
cell part morphogenesisGO:00329901370.014
regulation of transferase activityGO:00513383550.014
regulation of cell motilityGO:20001452990.014
cell projection organizationGO:00300302520.014
regulation of cytoskeleton organizationGO:00514931770.014
nephric duct developmentGO:007217640.014
regulation of defense responseGO:00313471540.014
blastocyst developmentGO:000182430.014
cell growthGO:00160491600.013
growthGO:00400072020.013
sequestering of metal ionGO:0051238240.013
multi organism cellular processGO:00447641560.013
cell projection morphogenesisGO:00488581290.013
positive regulation of programmed cell deathGO:00430682490.013
fatty acid elongation monounsaturated fatty acidGO:003462530.013
lipid biosynthetic processGO:00086101770.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
cell projection assemblyGO:00300311260.013
negative regulation of phosphorylationGO:00423261740.013
nucleoside monophosphate metabolic processGO:00091231910.013
single organism membrane fusionGO:0044801370.013
regulation of endopeptidase activityGO:00525481700.013
nuclear transportGO:00511691790.013
innate immune responseGO:00450871780.013
nucleotide catabolic processGO:00091664080.013
atp metabolic processGO:00460341760.013
protein catabolic processGO:00301633250.013
hemopoiesisGO:00300971800.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
epithelial cell proliferationGO:00506731280.013
inorganic cation transmembrane transportGO:00986621940.013
memoryGO:000761330.013
positive regulation of apoptotic processGO:00430652460.013
positive regulation of protein kinase activityGO:00458601900.013
small gtpase mediated signal transductionGO:0007264780.013
glycosyl compound catabolic processGO:19016584130.013
negative regulation of phosphate metabolic processGO:00459362670.013
immune effector processGO:00022521590.012
positive regulation of organelle organizationGO:00106381950.012
response to oxygen containing compoundGO:19017003690.012
positive regulation of protein phosphorylationGO:00019343130.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
limbic system developmentGO:002176130.012
blood vessel developmentGO:00015681720.012
positive regulation of transferase activityGO:00513472270.012
metal ion homeostasisGO:00550651690.012
positive regulation of cell migrationGO:00303351720.012
organelle assemblyGO:00709251760.012
modification dependent protein catabolic processGO:00199412090.012
microtubule cytoskeleton organizationGO:00002261760.012
regulation of protein transportGO:00512232130.012
organic acid biosynthetic processGO:0016053970.012
negative regulation of cell cycleGO:00457861930.012
spermatid differentiationGO:004851540.012
embryonic epithelial tube formationGO:000183840.012
mitotic cell cycleGO:00002783260.012
central nervous system developmentGO:00074171230.012
regulation of growthGO:00400081650.012
positive regulation of behaviorGO:0048520600.012
regulation of multi organism processGO:00439001570.012
synaptic vesicle recyclingGO:003646530.012
regulation of mapk cascadeGO:00434082620.012
taxisGO:00423301570.011
cell adhesionGO:00071553250.011
leukocyte migrationGO:00509001070.011
positive regulation of ion transportGO:0043270870.011
receptor mediated endocytosisGO:0006898840.011
cellular metal ion homeostasisGO:00068751460.011
positive regulation of protein transportGO:00512221350.011
organelle fusionGO:0048284360.011
positive regulation of cell deathGO:00109422630.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
regulation of apoptotic signaling pathwayGO:20012331750.011
associative learningGO:000830610.011
regulation of intracellular protein transportGO:00331571230.011
cellular response to cytokine stimulusGO:00713451810.011
fatty acid biosynthetic processGO:0006633460.011
mitochondrion organizationGO:00070051560.011
cellular protein complex assemblyGO:00436231880.011
regulation of protein maturationGO:19033171500.011
positive regulation of catabolic processGO:00098963100.011
regulation of protein processingGO:00706131500.011
cation transmembrane transportGO:00986552380.011
cerebral cortex neuron differentiationGO:002189510.011
mammary gland morphogenesisGO:006044320.011
regulation of dna metabolic processGO:00510521530.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
negative regulation of hydrolase activityGO:00513461820.011
muscle cell cellular homeostasisGO:004671630.011
negative regulation of organelle organizationGO:00106391260.011
cilium assemblyGO:0042384630.011
purine ribonucleotide catabolic processGO:00091544040.011
proteasomal protein catabolic processGO:00104981760.011
regulation of purine nucleotide catabolic processGO:00331212050.011
central nervous system projection neuron axonogenesisGO:002195230.011
rna interferenceGO:001624640.011
negative regulation of ligand dependent nuclear receptor transcription coactivator activityGO:200032610.011
hindbrain developmentGO:003090230.011
chromatin organizationGO:00063253510.011
head developmentGO:00603221080.010
negative regulation of protein processingGO:00109551420.010
defense response to other organismGO:00985421290.010
ion transmembrane transportGO:00342203380.010
positive regulation of apoptotic signaling pathwayGO:2001235700.010
regulation of protein serine threonine kinase activityGO:00719001790.010
nervous system developmentGO:00073992930.010
cell developmentGO:00484683280.010
modification dependent macromolecule catabolic processGO:00436322120.010
nadph oxidationGO:007099530.010
regulation of ion transportGO:00432691890.010
negative regulation of nucleocytoplasmic transportGO:0046823370.010
regulation of cell divisionGO:00513021160.010
establishment of protein localization to membraneGO:00901501210.010
positive regulation of nucleotide catabolic processGO:00308131850.010
regulation of proteolysisGO:00301622930.010
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.010
adult locomotory behaviorGO:000834410.010
apoptotic signaling pathwayGO:00971902680.010
negative regulation of intracellular signal transductionGO:19025321830.010
dephosphorylationGO:00163112090.010
regulation of reactive oxygen species metabolic processGO:2000377410.010
very long chain fatty acid biosynthetic processGO:004276170.010
negative regulation of protein modification processGO:00314002000.010
central nervous system neuron axonogenesisGO:002195530.010

PSENEN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
integumentary system diseaseDOID:16430.111
cancerDOID:1621670.029
disease of cellular proliferationDOID:145661740.029
musculoskeletal system diseaseDOID:172230.025
muscular diseaseDOID:00800001140.025
muscle tissue diseaseDOID:661130.025
disease of mental healthDOID:150700.021
skin diseaseDOID:37330.017
nervous system diseaseDOID:8634310.012
central nervous system diseaseDOID:3311860.012
heart diseaseDOID:114680.011
cardiovascular system diseaseDOID:12871060.011
myopathyDOID:4231040.010
intrinsic cardiomyopathyDOID:0060036500.010
cardiomyopathyDOID:0050700500.010
dilated cardiomyopathyDOID:12930320.010
organ system cancerDOID:00506861640.010
sweat gland diseaseDOID:138330.001
hidradenitisDOID:228230.001
hidradenitis suppurativaDOID:228030.001