| endomembrane system organization | GO:0010256 | 196 | 0.528 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.357 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.228 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.223 | Yeast Fly |
| golgi organization | GO:0007030 | 38 | 0.195 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.192 | |
| post embryonic development | GO:0009791 | 2 | 0.174 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.174 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.174 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.167 | |
| er to golgi vesicle mediated transport | GO:0006888 | 19 | 0.156 | Yeast Fly |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.150 | |
| establishment of protein localization to membrane | GO:0090150 | 121 | 0.148 | |
| secretion by cell | GO:0032940 | 226 | 0.145 | Fly |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.122 | |
| intracellular protein transport | GO:0006886 | 270 | 0.119 | Fly |
| gtp catabolic process | GO:0006184 | 237 | 0.113 | |
| oocyte differentiation | GO:0009994 | 2 | 0.109 | |
| guanosine containing compound metabolic process | GO:1901068 | 244 | 0.108 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.105 | |
| protein glycosylation | GO:0006486 | 62 | 0.103 | |
| golgi vesicle budding | GO:0048194 | 4 | 0.099 | |
| membrane organization | GO:0061024 | 292 | 0.097 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.096 | |
| maintenance of location | GO:0051235 | 112 | 0.093 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.092 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.090 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.088 | |
| plasma membrane organization | GO:0007009 | 115 | 0.086 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.084 | |
| growth | GO:0040007 | 202 | 0.083 | |
| single organism membrane organization | GO:0044802 | 268 | 0.081 | |
| protein localization to plasma membrane | GO:0072659 | 93 | 0.079 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.079 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.078 | |
| protein targeting to membrane | GO:0006612 | 42 | 0.070 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.067 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.066 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.065 | |
| secretion | GO:0046903 | 254 | 0.065 | Fly |
| nervous system development | GO:0007399 | 293 | 0.063 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.061 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.061 | |
| endoplasmic reticulum organization | GO:0007029 | 20 | 0.060 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.060 | |
| exocytosis | GO:0006887 | 71 | 0.059 | |
| glycosylation | GO:0070085 | 71 | 0.059 | |
| protein n linked glycosylation | GO:0006487 | 23 | 0.054 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.053 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.051 | |
| locomotory behavior | GO:0007626 | 1 | 0.050 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.048 | |
| macromolecule glycosylation | GO:0043413 | 63 | 0.047 | |
| lipid localization | GO:0010876 | 106 | 0.047 | |
| protein o linked glycosylation via serine | GO:0018242 | 3 | 0.047 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.046 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.046 | |
| segmentation | GO:0035282 | 4 | 0.046 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.045 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.045 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.044 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.043 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.043 | |
| primary neural tube formation | GO:0014020 | 3 | 0.042 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.042 | |
| embryo development | GO:0009790 | 123 | 0.041 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.041 | |
| hindbrain development | GO:0030902 | 3 | 0.040 | |
| protein targeting | GO:0006605 | 187 | 0.040 | |
| gtp metabolic process | GO:0046039 | 239 | 0.040 | |
| single organism cellular localization | GO:1902580 | 332 | 0.039 | |
| circulatory system development | GO:0072359 | 262 | 0.038 | |
| oogenesis | GO:0048477 | 2 | 0.037 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.036 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.033 | |
| establishment of protein localization to plasma membrane | GO:0090002 | 68 | 0.033 | |
| endocytosis | GO:0006897 | 159 | 0.031 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.031 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.030 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.030 | |
| cytokinesis | GO:0000910 | 96 | 0.029 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.028 | |
| cellular amide metabolic process | GO:0043603 | 69 | 0.028 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.028 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.027 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.027 | Fly |
| somitogenesis | GO:0001756 | 2 | 0.027 | |
| metencephalon development | GO:0022037 | 2 | 0.026 | |
| oocyte development | GO:0048599 | 1 | 0.026 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.026 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.025 | |
| chaperone mediated protein folding | GO:0061077 | 13 | 0.025 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.025 | Fly |
| maintenance of protein location | GO:0045185 | 57 | 0.025 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.024 | |
| neural tube formation | GO:0001841 | 3 | 0.024 | |
| negative regulation of nucleotide metabolic process | GO:0045980 | 29 | 0.024 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.023 | |
| cell division | GO:0051301 | 168 | 0.023 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.023 | |
| reproductive process | GO:0022414 | 106 | 0.023 | Fly |
| positive regulation of blood pressure | GO:0045777 | 3 | 0.022 | |
| single organism membrane budding | GO:1902591 | 10 | 0.022 | |
| female gamete generation | GO:0007292 | 2 | 0.022 | |
| protein localization to endoplasmic reticulum | GO:0070972 | 19 | 0.021 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.021 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.021 | |
| establishment of organelle localization | GO:0051656 | 59 | 0.021 | |
| toxin transport | GO:1901998 | 4 | 0.021 | |
| protein localization to membrane | GO:0072657 | 160 | 0.020 | |
| postsynaptic membrane organization | GO:0001941 | 2 | 0.020 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.020 | |
| cell development | GO:0048468 | 328 | 0.020 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.019 | |
| regulation of vesicle mediated transport | GO:0060627 | 130 | 0.019 | |
| negative regulation of purine nucleotide metabolic process | GO:1900543 | 28 | 0.019 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.018 | |
| multicellular organismal reproductive process | GO:0048609 | 40 | 0.018 | Fly |
| reproduction | GO:0000003 | 63 | 0.018 | Fly |
| protein localization to organelle | GO:0033365 | 280 | 0.018 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.017 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 21 | 0.017 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.017 | |
| cell morphogenesis | GO:0000902 | 296 | 0.017 | |
| vesicle targeting to from or within golgi | GO:0048199 | 6 | 0.017 | |
| negative regulation of gtpase activity | GO:0034260 | 11 | 0.017 | |
| vesicle organization | GO:0016050 | 62 | 0.017 | |
| regulation of cell division | GO:0051302 | 116 | 0.017 | |
| protein catabolic process | GO:0030163 | 325 | 0.017 | |
| embryonic placenta development | GO:0001892 | 1 | 0.017 | |
| single organism reproductive process | GO:0044702 | 98 | 0.017 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.017 | |
| system process | GO:0003008 | 349 | 0.016 | |
| actin filament based process | GO:0030029 | 224 | 0.016 | |
| brain development | GO:0007420 | 97 | 0.016 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.016 | |
| behavior | GO:0007610 | 112 | 0.016 | Fly |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.016 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.016 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.016 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.016 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.015 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.015 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.015 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.015 | |
| amino sugar catabolic process | GO:0046348 | 3 | 0.015 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.015 | |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.014 | |
| nucleocytoplasmic transport | GO:0006913 | 176 | 0.014 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.014 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.014 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.014 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.014 | |
| regeneration | GO:0031099 | 4 | 0.014 | |
| protein stabilization | GO:0050821 | 64 | 0.014 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.014 | |
| alpha amino acid metabolic process | GO:1901605 | 72 | 0.014 | |
| adult locomotory behavior | GO:0008344 | 1 | 0.014 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.014 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.014 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.014 | |
| regulation of growth | GO:0040008 | 165 | 0.014 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.014 | |
| regulation of wnt protein secretion | GO:0061356 | 1 | 0.014 | Fly |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.013 | |
| generation of neurons | GO:0048699 | 152 | 0.013 | |
| epidermis morphogenesis | GO:0048730 | 3 | 0.013 | |
| membrane budding | GO:0006900 | 28 | 0.013 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.013 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.013 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 0.013 | |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.013 | |
| response to inorganic substance | GO:0010035 | 127 | 0.013 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 4 | 0.013 | |
| pancreatic juice secretion | GO:0030157 | 4 | 0.013 | |
| positive regulation of protein catabolic process | GO:0045732 | 75 | 0.013 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.013 | |
| protein folding | GO:0006457 | 38 | 0.013 | |
| response to cytokine | GO:0034097 | 232 | 0.013 | |
| t cell activation | GO:0042110 | 99 | 0.013 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.013 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.013 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.013 | |
| regulation of protein stability | GO:0031647 | 87 | 0.013 | |
| negative regulation of nucleoside metabolic process | GO:0045978 | 18 | 0.012 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.012 | |
| reactive nitrogen species metabolic process | GO:2001057 | 3 | 0.012 | |
| cell projection organization | GO:0030030 | 252 | 0.012 | |
| tube closure | GO:0060606 | 3 | 0.012 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 31 | 0.012 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.012 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 37 | 0.012 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.012 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.012 | |
| neural tube closure | GO:0001843 | 3 | 0.012 | |
| neurogenesis | GO:0022008 | 169 | 0.012 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.012 | |
| regulation of locomotion | GO:0040012 | 329 | 0.012 | |
| copii vesicle coating | GO:0048208 | 2 | 0.012 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.012 | |
| protein targeting to plasma membrane | GO:0072661 | 13 | 0.012 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.012 | |
| negative regulation of response to external stimulus | GO:0032102 | 83 | 0.011 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.011 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.011 | |
| neuron development | GO:0048666 | 113 | 0.011 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.011 | |
| regulation of protein localization | GO:0032880 | 296 | 0.011 | Fly |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.011 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.011 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.011 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.011 | |
| regulation of cell adhesion | GO:0030155 | 166 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.011 | |
| regulation of protein secretion | GO:0050708 | 86 | 0.011 | Fly |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 181 | 0.011 | |
| regulation of meiotic cell cycle | GO:0051445 | 4 | 0.011 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.011 | |
| chloride transport | GO:0006821 | 41 | 0.011 | |
| small molecule biosynthetic process | GO:0044283 | 157 | 0.011 | |
| lipid storage | GO:0019915 | 28 | 0.011 | |
| regulation of mitotic cell cycle | GO:0007346 | 189 | 0.011 | |
| response to unfolded protein | GO:0006986 | 24 | 0.011 | |
| neuron differentiation | GO:0030182 | 138 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.010 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.010 | |
| regulation of protein localization to nucleus | GO:1900180 | 85 | 0.010 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.010 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.010 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.010 | |
| organelle localization | GO:0051640 | 84 | 0.010 | |
| regulation of cell development | GO:0060284 | 161 | 0.010 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.010 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.010 | |
| rna interference | GO:0016246 | 4 | 0.010 | |