Homo sapiens

64 known processes

ISG20

interferon stimulated exonuclease gene 20kDa

(Aliases: HEM45,CD25)

ISG20 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523150.404
detection of chemical stimulus involved in sensory perceptionGO:0050907330.379
response to other organismGO:00517072610.293
response to external biotic stimulusGO:00432072610.203
interleukin 4 biosynthetic processGO:004209720.142
response to biotic stimulusGO:00096072760.132
positive regulation of interleukin 13 productionGO:003273640.128
positive regulation of developmental processGO:00510943140.107
positive regulation of defense responseGO:0031349870.101
response to abiotic stimulusGO:00096283360.091
response to virusGO:00096151260.090
positive regulation of interferon beta productionGO:0032728170.085
cytoplasmic transportGO:00164823790.084
defense response to other organismGO:00985421290.083
immune response activating signal transductionGO:0002757900.081
chemical homeostasisGO:00488783060.078
positive regulation of immune system processGO:00026842830.078
regulation of immune responseGO:00507762010.075
positive regulation of interleukin 4 biosynthetic processGO:004540410.075
hematopoietic or lymphoid organ developmentGO:00485341860.073
regulation of cytokine productionGO:00018172320.070
viral life cycleGO:00190581320.067
negative regulation of hydrolase activityGO:00513461820.065
purine nucleoside triphosphate catabolic processGO:00091463920.065
positive regulation of cell deathGO:00109422630.062
hemopoiesisGO:00300971800.061
immune responseGO:00069553070.061
biological adhesionGO:00226103310.059
defense response to virusGO:0051607710.057
negative regulation of apoptotic processGO:00430663160.056
carbohydrate metabolic processGO:00059752070.055
negative regulation of catalytic activityGO:00430863350.055
nucleoside phosphate biosynthetic processGO:19012931090.053
interleukin 13 productionGO:003261670.053
negative regulation of cell deathGO:00605483450.052
cellular macromolecule catabolic processGO:00442653800.051
glycosyl compound catabolic processGO:19016584130.050
regulation of apoptotic signaling pathwayGO:20012331750.049
post embryonic developmentGO:000979120.048
cellular protein catabolic processGO:00442572610.048
determination of adult lifespanGO:000834020.048
purine containing compound catabolic processGO:00725234110.047
regulation of cell cycleGO:00517263930.046
protein oligomerizationGO:00512591730.046
sensory perception of bitter tasteGO:0050913280.044
negative regulation of apoptotic signaling pathwayGO:2001234970.044
system processGO:00030083490.043
activation of immune responseGO:00022531140.042
purine nucleoside triphosphate metabolic processGO:00091444120.041
ribonucleoside triphosphate catabolic processGO:00092033910.041
protein maturationGO:00516042330.040
sensory perceptionGO:00076001030.039
ribonucleoside triphosphate metabolic processGO:00091994120.039
positive regulation of interleukin 4 productionGO:003275330.039
ion homeostasisGO:00508012300.039
positive regulation of apoptotic processGO:00430652460.039
regulation of cell differentiationGO:00455953930.038
nucleoside phosphate catabolic processGO:19012924120.037
regulation of cell migrationGO:00303342890.036
immune system developmentGO:00025201950.036
regulation of regulatory t cell differentiationGO:004558940.036
glucose metabolic processGO:0006006450.036
response to cytokineGO:00340972320.035
immune response regulating signaling pathwayGO:0002764970.035
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.035
negative regulation of programmed cell deathGO:00430693210.034
carbohydrate derivative biosynthetic processGO:19011372070.034
cation transportGO:00068123310.033
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.033
mitochondrion organizationGO:00070051560.033
cellular response to cytokine stimulusGO:00713451810.032
extrinsic apoptotic signaling pathwayGO:00971911190.032
positive regulation of interferon alpha productionGO:0032727110.031
purine nucleotide biosynthetic processGO:0006164840.031
amine metabolic processGO:0009308440.030
cell adhesionGO:00071553250.029
positive regulation of cell differentiationGO:00455972110.029
cellular response to abiotic stimulusGO:00712141170.029
regulation of immune effector processGO:0002697910.029
cellular response to external stimulusGO:00714961110.028
antigen processing and presentation via mhc class ibGO:000247530.028
negative regulation of protein metabolic processGO:00512483910.028
purine nucleoside catabolic processGO:00061523980.028
purine nucleoside monophosphate catabolic processGO:00091281580.028
nucleoside triphosphate catabolic processGO:00091433940.028
interferon alpha productionGO:0032607110.027
nucleotide catabolic processGO:00091664080.027
purine ribonucleotide catabolic processGO:00091544040.027
single organism carbohydrate metabolic processGO:00447231930.027
symbiosis encompassing mutualism through parasitismGO:00444031560.027
response to peptidoglycanGO:003249430.027
organonitrogen compound biosynthetic processGO:19015662000.027
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.027
ribonucleotide catabolic processGO:00092614050.026
purine nucleotide catabolic processGO:00061954050.026
cellular amine metabolic processGO:0044106410.026
negative regulation of cell cycleGO:00457861930.026
response to bacteriumGO:00096171440.026
interspecies interaction between organismsGO:00444191560.025
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.025
nucleoside catabolic processGO:00091644080.024
ribonucleoside catabolic processGO:00424544060.024
regulation of adaptive immune responseGO:0002819330.024
regulation of cellular component movementGO:00512703340.024
proteolysis involved in cellular protein catabolic processGO:00516032440.023
positive regulation of interleukin 2 productionGO:0032743110.023
regulation of cysteine type endopeptidase activityGO:20001161270.023
leukocyte differentiationGO:0002521980.023
regulation of defense responseGO:00313471540.023
negative regulation of cysteine type endopeptidase activityGO:2000117480.023
activation of innate immune responseGO:0002218550.022
regulation of cellular amino acid metabolic processGO:000652160.022
nucleoside triphosphate metabolic processGO:00091414220.022
single organism cellular localizationGO:19025803320.022
multicellular organismal agingGO:001025930.022
apoptotic signaling pathwayGO:00971902680.022
positive regulation of immune responseGO:00507781590.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
pattern recognition receptor signaling pathwayGO:0002221480.021
glycoprotein biosynthetic processGO:0009101910.021
positive regulation of natural killer cell mediated immunityGO:0002717120.021
purine ribonucleoside metabolic processGO:00461284370.021
anatomical structure homeostasisGO:00602491000.021
regulation of cellular ketone metabolic processGO:0010565500.021
regulation of interleukin 4 biosynthetic processGO:004540220.021
viral processGO:00160321460.021
positive regulation of programmed cell deathGO:00430682490.021
cd8 positive alpha beta t cell proliferationGO:003574010.021
detection of stimulus involved in sensory perceptionGO:0050906430.021
oogenesisGO:004847720.021
leukocyte activationGO:00453211640.021
cellular response to mechanical stimulusGO:0071260390.020
purine ribonucleoside catabolic processGO:00461303980.020
single organism membrane organizationGO:00448022680.020
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
regulation of multi organism processGO:00439001570.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
metal ion transportGO:00300012720.020
protein processingGO:00164852260.020
regulation of cell motilityGO:20001452990.020
regulation of interferon beta productionGO:0032648220.020
glycosylationGO:0070085710.019
positive regulation of cytokine productionGO:00018191670.019
interleukin 10 biosynthetic processGO:004209120.019
glycoprotein metabolic processGO:00091001100.019
proteasomal protein catabolic processGO:00104981760.019
organophosphate catabolic processGO:00464344300.019
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.019
cellular response to dna damage stimulusGO:00069743790.019
protein catabolic processGO:00301633250.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
cell cycle arrestGO:0007050710.018
membrane organizationGO:00610242920.018
modification dependent protein catabolic processGO:00199412090.018
protein acylationGO:00435431380.018
innate immune responseGO:00450871780.018
negative regulation of immune system processGO:00026831360.018
monosaccharide metabolic processGO:0005996740.018
neurological system processGO:00508771630.017
rna catabolic processGO:0006401710.017
multi organism cellular processGO:00447641560.017
atp metabolic processGO:00460341760.017
leukocyte mediated immunityGO:0002443590.017
regulation of protein maturationGO:19033171500.017
protein localization to organelleGO:00333652800.017
antigen processing and presentationGO:0019882330.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.017
negative regulation of developmental processGO:00510932470.017
regulation of interferon alpha productionGO:0032647110.017
negative regulation of multicellular organismal processGO:00512413170.017
sensory perception of tasteGO:0050909360.017
lymphocyte mediated immunityGO:0002449480.017
modification dependent macromolecule catabolic processGO:00436322120.017
nucleoside monophosphate metabolic processGO:00091231910.016
regulation of viral genome replicationGO:0045069480.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
lipoprotein biosynthetic processGO:0042158330.016
protein localization to membraneGO:00726571600.016
organophosphate biosynthetic processGO:00904071630.016
regulation of protein processingGO:00706131500.016
purine containing compound biosynthetic processGO:0072522880.016
regulation of membrane potentialGO:0042391950.016
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.016
mitotic cell cycleGO:00002783260.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
immune response regulating cell surface receptor signaling pathwayGO:0002768510.015
detection of stimulusGO:0051606850.015
negative regulation of cell differentiationGO:00455961710.015
regulation of anatomical structure morphogenesisGO:00226032860.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.015
negative regulation of protein maturationGO:19033181420.015
sensory perception of chemical stimulusGO:0007606380.015
type i interferon biosynthetic processGO:004535140.015
regulation of proteolysisGO:00301622930.015
cellular ketone metabolic processGO:0042180800.014
negative regulation of phosphorus metabolic processGO:00105632670.014
positive regulation of type i interferon productionGO:0032481200.014
positive regulation of regulatory t cell differentiationGO:004559130.014
regenerationGO:003109940.014
negative regulation of multi organism processGO:0043901920.014
negative regulation of cellular protein metabolic processGO:00322693530.014
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.014
regulation of intracellular transportGO:00323861950.014
response to interferon gammaGO:0034341390.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
regulation of innate immune responseGO:0045088970.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
negative regulation of intracellular signal transductionGO:19025321830.013
positive regulation of innate immune responseGO:0045089790.013
intracellular protein transportGO:00068862700.013
cd4 positive alpha beta t cell differentiationGO:004336740.013
negative regulation of endopeptidase activityGO:0010951840.013
negative regulation of protein modification processGO:00314002000.013
regulation of gtp catabolic processGO:00331241800.013
tissue migrationGO:00901301190.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
growthGO:00400072020.013
detection of chemical stimulusGO:0009593550.013
macromolecule glycosylationGO:0043413630.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
negative regulation of peptidase activityGO:0010466910.013
negative regulation of phosphate metabolic processGO:00459362670.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
response to mechanical stimulusGO:0009612510.012
regulation of cell growthGO:00015581350.012
negative regulation of cell motilityGO:20001461040.012
taxisGO:00423301570.012
regulation of endopeptidase activityGO:00525481700.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of peptidase activityGO:00525471800.012
cell projection organizationGO:00300302520.012
plasma membrane organizationGO:00070091150.012
anion transportGO:00068201610.012
interferon beta productionGO:0032608230.012
t cell differentiation in thymusGO:003307740.012
actin filament based processGO:00300292240.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
negative regulation of proteolysisGO:00458611320.012
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.012
cytokine metabolic processGO:0042107380.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
positive regulation of transportGO:00510503360.011
regulation of leukocyte activationGO:00026941150.011
defense response to fungusGO:005083240.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
cell growthGO:00160491600.011
protein lipidationGO:0006497330.011
mitotic cell cycle processGO:19030472860.011
lymphocyte differentiationGO:0030098350.011
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.011
regulation of nuclease activityGO:0032069110.011
response to organonitrogen compoundGO:00102431560.011
negative regulation of cell proliferationGO:00082852280.011
secretionGO:00469032540.011
positive regulation of cellular component organizationGO:00511303760.011
regulation of homeostatic processGO:00328441210.011
interleukin 13 biosynthetic processGO:004223110.011
positive regulation of lymphocyte differentiationGO:0045621130.011
cytokine mediated signaling pathwayGO:00192211090.011
regulation of cell adhesionGO:00301551660.011
positive regulation of locomotionGO:00400171860.011
regulation of bindingGO:00510981110.011
retina homeostasisGO:0001895420.011
negative regulation of phosphorylationGO:00423261740.011
posttranscriptional regulation of gene expressionGO:00106082130.011
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.011
positive regulation of interleukin 13 biosynthetic processGO:004536810.011
response to oxygen containing compoundGO:19017003690.011
cell activationGO:00017752130.011
lipoprotein metabolic processGO:0042157420.011
regulation of viral processGO:00507921030.010
cation homeostasisGO:00550801890.010
ras protein signal transductionGO:0007265730.010
vesicle mediated transportGO:00161923710.010
protein modification by small protein conjugationGO:00324463420.010
endomembrane system organizationGO:00102561960.010
response to nitrogen compoundGO:19016981840.010
establishment of protein localization to membraneGO:00901501210.010
nitrogen compound transportGO:00717051910.010
syncytium formation by plasma membrane fusionGO:000076820.010
epithelial cell migrationGO:00106311190.010
cytokine productionGO:00018162470.010
cellular homeostasisGO:00197251960.010
leukocyte proliferationGO:0070661740.010
immune response inhibiting signal transductionGO:000276540.010

ISG20 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.031
disease of cellular proliferationDOID:145661740.025
cancerDOID:1621670.025
organ system cancerDOID:00506861640.023
immune system diseaseDOID:29141550.013
gastrointestinal system cancerDOID:3119520.011