| protein folding | GO:0006457 | 38 | 0.985 | |
| response to unfolded protein | GO:0006986 | 24 | 0.957 | Worm |
| post embryonic development | GO:0009791 | 2 | 0.853 | Worm |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 16 | 0.745 | Worm |
| protein n linked glycosylation via asparagine | GO:0018279 | 10 | 0.697 | |
| protein n linked glycosylation | GO:0006487 | 23 | 0.635 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.433 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.421 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 31 | 0.398 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.376 | |
| cellular response to unfolded protein | GO:0034620 | 16 | 0.347 | Worm |
| protein glycosylation | GO:0006486 | 62 | 0.346 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.290 | Worm |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.243 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.242 | |
| chaperone mediated protein folding | GO:0061077 | 13 | 0.240 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.235 | |
| protein oxidation | GO:0018158 | 5 | 0.221 | |
| oxidation reduction process | GO:0055114 | 396 | 0.201 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.190 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.185 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.183 | |
| system process | GO:0003008 | 349 | 0.182 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.166 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.163 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.160 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.159 | Worm |
| protein catabolic process | GO:0030163 | 325 | 0.158 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.153 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.153 | |
| cellular response to oxidative stress | GO:0034599 | 85 | 0.150 | |
| response to decreased oxygen levels | GO:0036293 | 96 | 0.148 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.147 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.144 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.142 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.136 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.136 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.135 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.133 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 116 | 0.128 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.127 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.113 | |
| embryo development | GO:0009790 | 123 | 0.112 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.110 | |
| glycosylation | GO:0070085 | 71 | 0.110 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.106 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.101 | |
| cellular response to superoxide | GO:0071451 | 6 | 0.098 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.097 | |
| tissue homeostasis | GO:0001894 | 63 | 0.092 | |
| endoplasmic reticulum organization | GO:0007029 | 20 | 0.091 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.091 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.090 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.089 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.086 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.086 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.085 | |
| protein maturation | GO:0051604 | 233 | 0.085 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.085 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.084 | |
| heat acclimation | GO:0010286 | 3 | 0.084 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.083 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.082 | |
| cellular modified amino acid metabolic process | GO:0006575 | 64 | 0.078 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.077 | |
| endocytosis | GO:0006897 | 159 | 0.077 | |
| cellular response to organonitrogen compound | GO:0071417 | 124 | 0.075 | |
| hindbrain development | GO:0030902 | 3 | 0.074 | |
| protein processing | GO:0016485 | 226 | 0.074 | |
| response to organonitrogen compound | GO:0010243 | 156 | 0.073 | |
| maintenance of location | GO:0051235 | 112 | 0.069 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.068 | |
| cell division | GO:0051301 | 168 | 0.063 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.062 | |
| regulation of growth | GO:0040008 | 165 | 0.062 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.061 | |
| response to temperature stimulus | GO:0009266 | 22 | 0.060 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 264 | 0.058 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.058 | |
| retina homeostasis | GO:0001895 | 42 | 0.058 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.057 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.057 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.057 | |
| response to organophosphorus | GO:0046683 | 41 | 0.056 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.056 | |
| bone development | GO:0060348 | 26 | 0.055 | |
| oogenesis | GO:0048477 | 2 | 0.055 | |
| hydrogen peroxide metabolic process | GO:0042743 | 20 | 0.054 | |
| response to bacterium | GO:0009617 | 144 | 0.053 | |
| regulation of cell motility | GO:2000145 | 299 | 0.052 | |
| cellular response to hydrogen peroxide | GO:0070301 | 37 | 0.051 | |
| intracellular protein transport | GO:0006886 | 270 | 0.051 | |
| regulation of locomotion | GO:0040012 | 329 | 0.051 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.050 | |
| regulation of nucleoside metabolic process | GO:0009118 | 209 | 0.049 | |
| cation transport | GO:0006812 | 331 | 0.049 | |
| response to inorganic substance | GO:0010035 | 127 | 0.049 | |
| oocyte differentiation | GO:0009994 | 2 | 0.049 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.048 | |
| lipid localization | GO:0010876 | 106 | 0.048 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.048 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.046 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.046 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.046 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.045 | |
| regulation of atp metabolic process | GO:1903578 | 29 | 0.043 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.043 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.043 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.042 | |
| regulation of cell migration | GO:0030334 | 289 | 0.042 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.042 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.039 | |
| protein transmembrane transport | GO:0071806 | 25 | 0.039 | |
| skeletal system development | GO:0001501 | 79 | 0.038 | |
| circulatory system process | GO:0003013 | 113 | 0.038 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.038 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.038 | |
| positive regulation of protein kinase activity | GO:0045860 | 190 | 0.038 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.037 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.037 | |
| cellular homeostasis | GO:0019725 | 196 | 0.037 | |
| peptidyl asparagine modification | GO:0018196 | 11 | 0.037 | |
| response to nitrogen compound | GO:1901698 | 184 | 0.037 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.036 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.036 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.036 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.035 | |
| multicellular organismal homeostasis | GO:0048871 | 67 | 0.034 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.034 | |
| growth | GO:0040007 | 202 | 0.033 | |
| response to other organism | GO:0051707 | 261 | 0.033 | |
| transforming growth factor beta receptor signaling pathway | GO:0007179 | 76 | 0.033 | |
| positive regulation of growth | GO:0045927 | 58 | 0.032 | |
| regulation of protein processing | GO:0070613 | 150 | 0.032 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.032 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.032 | |
| sensory organ development | GO:0007423 | 52 | 0.031 | |
| regulation of behavior | GO:0050795 | 82 | 0.031 | |
| response to wounding | GO:0009611 | 168 | 0.031 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.030 | |
| response to topologically incorrect protein | GO:0035966 | 29 | 0.030 | Worm |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.030 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.030 | |
| anterior posterior axis specification | GO:0009948 | 2 | 0.030 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.030 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.030 | |
| response to oxidative stress | GO:0006979 | 121 | 0.029 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.029 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.029 | |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 81 | 0.029 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.028 | |
| regulation of atpase activity | GO:0043462 | 25 | 0.028 | |
| regulation of membrane potential | GO:0042391 | 95 | 0.028 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 185 | 0.027 | |
| cytokinesis | GO:0000910 | 96 | 0.027 | |
| developmental growth | GO:0048589 | 48 | 0.027 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.026 | |
| actin filament organization | GO:0007015 | 128 | 0.026 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.025 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.025 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 49 | 0.025 | |
| locomotory behavior | GO:0007626 | 1 | 0.025 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.024 | |
| response to transforming growth factor beta | GO:0071559 | 94 | 0.024 | |
| reproduction | GO:0000003 | 63 | 0.024 | |
| actin cytoskeleton organization | GO:0030036 | 207 | 0.024 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.024 | |
| regulation of phosphoprotein phosphatase activity | GO:0043666 | 23 | 0.024 | |
| response to hypoxia | GO:0001666 | 96 | 0.024 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.024 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.023 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.023 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.023 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.023 | |
| lymphocyte activation | GO:0046649 | 133 | 0.023 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.022 | |
| regulation of response to wounding | GO:1903034 | 101 | 0.022 | |
| metencephalon development | GO:0022037 | 2 | 0.022 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.022 | |
| nervous system development | GO:0007399 | 293 | 0.022 | |
| single organism cellular localization | GO:1902580 | 332 | 0.022 | |
| immune effector process | GO:0002252 | 159 | 0.022 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.022 | |
| peptidyl cysteine modification | GO:0018198 | 9 | 0.022 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 34 | 0.022 | |
| somitogenesis | GO:0001756 | 2 | 0.022 | |
| inflammatory response | GO:0006954 | 79 | 0.022 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 94 | 0.022 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.022 | |
| neural tube formation | GO:0001841 | 3 | 0.022 | |
| dephosphorylation | GO:0016311 | 209 | 0.021 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.021 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.021 | |
| response to lipid | GO:0033993 | 206 | 0.021 | |
| membrane organization | GO:0061024 | 292 | 0.021 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.021 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.021 | |
| alpha amino acid metabolic process | GO:1901605 | 72 | 0.020 | |
| skin development | GO:0043588 | 76 | 0.020 | |
| peptidyl cysteine oxidation | GO:0018171 | 1 | 0.020 | |
| negative regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043154 | 46 | 0.020 | |
| response to toxic substance | GO:0009636 | 37 | 0.020 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.019 | |
| positive regulation of blood pressure | GO:0045777 | 3 | 0.019 | |
| reproductive system development | GO:0061458 | 56 | 0.019 | |
| cerebellar cortex development | GO:0021695 | 1 | 0.019 | |
| pigment biosynthetic process | GO:0046148 | 10 | 0.019 | |
| positive regulation of developmental growth | GO:0048639 | 16 | 0.019 | |
| maintenance of protein location | GO:0045185 | 57 | 0.019 | |
| regulation of binding | GO:0051098 | 111 | 0.019 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.019 | |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.018 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.018 | |
| cyclic nucleotide biosynthetic process | GO:0009190 | 61 | 0.018 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.018 | |
| cell development | GO:0048468 | 328 | 0.018 | |
| sex differentiation | GO:0007548 | 45 | 0.018 | |
| cellular response to toxic substance | GO:0097237 | 4 | 0.017 | |
| peptide cross linking | GO:0018149 | 12 | 0.017 | |
| actin filament based process | GO:0030029 | 224 | 0.017 | |
| single organism membrane organization | GO:0044802 | 268 | 0.017 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.017 | |
| t cell activation | GO:0042110 | 99 | 0.017 | |
| leukocyte activation | GO:0045321 | 164 | 0.017 | |
| segmentation | GO:0035282 | 4 | 0.017 | |
| eye pigmentation | GO:0048069 | 1 | 0.016 | |
| regulation of cytokine production | GO:0001817 | 232 | 0.016 | |
| regulation of purine nucleotide biosynthetic process | GO:1900371 | 50 | 0.016 | |
| developmental process involved in reproduction | GO:0003006 | 66 | 0.016 | |
| reproductive process | GO:0022414 | 106 | 0.016 | |
| protein localization to organelle | GO:0033365 | 280 | 0.016 | |
| cellular response to organic cyclic compound | GO:0071407 | 127 | 0.016 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.015 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.015 | |
| protein stabilization | GO:0050821 | 64 | 0.015 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.015 | |
| regulation of nucleotide catabolic process | GO:0030811 | 205 | 0.015 | |
| regulation of defense response | GO:0031347 | 154 | 0.015 | |
| regulation of gtp catabolic process | GO:0033124 | 180 | 0.015 | |
| cellular response to reactive oxygen species | GO:0034614 | 50 | 0.015 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.015 | |
| cellular response to lipid | GO:0071396 | 127 | 0.015 | |
| male genitalia development | GO:0030539 | 1 | 0.015 | |
| transmembrane transport | GO:0055085 | 399 | 0.015 | |
| camp biosynthetic process | GO:0006171 | 47 | 0.015 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.015 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.014 | |
| cell activation | GO:0001775 | 213 | 0.014 | |
| pyrimidine nucleotide biosynthetic process | GO:0006221 | 2 | 0.014 | |
| response to purine containing compound | GO:0014074 | 40 | 0.014 | |
| regulation of cell morphogenesis | GO:0022604 | 153 | 0.014 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 158 | 0.014 | |
| male sex differentiation | GO:0046661 | 25 | 0.014 | |
| regulation of protein stability | GO:0031647 | 87 | 0.014 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 85 | 0.014 | |
| negative regulation of cysteine type endopeptidase activity | GO:2000117 | 48 | 0.014 | |
| endomembrane system organization | GO:0010256 | 196 | 0.014 | |
| mitochondrion organization | GO:0007005 | 156 | 0.013 | |
| hydrogen peroxide catabolic process | GO:0042744 | 13 | 0.013 | |
| response to hormone | GO:0009725 | 175 | 0.013 | |
| negative regulation of transferase activity | GO:0051348 | 124 | 0.013 | |
| multicellular organismal reproductive process | GO:0048609 | 40 | 0.013 | |
| macromolecule glycosylation | GO:0043413 | 63 | 0.013 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.013 | |
| cell chemotaxis | GO:0060326 | 112 | 0.013 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.013 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.013 | |
| calcium mediated signaling | GO:0019722 | 44 | 0.013 | |
| immune response | GO:0006955 | 307 | 0.013 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.012 | |
| synaptic vesicle endocytosis | GO:0048488 | 2 | 0.012 | |
| regulation of mitochondrial membrane potential | GO:0051881 | 23 | 0.012 | |
| regulation of developmental growth | GO:0048638 | 30 | 0.012 | |
| generation of neurons | GO:0048699 | 152 | 0.012 | |
| oocyte development | GO:0048599 | 1 | 0.012 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.012 | |
| multi organism reproductive process | GO:0044703 | 54 | 0.012 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.012 | |
| lipid storage | GO:0019915 | 28 | 0.012 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.012 | |
| regulation of blood vessel size | GO:0050880 | 18 | 0.011 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.011 | |
| positive regulation of cellular component organization | GO:0051130 | 376 | 0.011 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 26 | 0.011 | |
| blood circulation | GO:0008015 | 113 | 0.011 | |
| head development | GO:0060322 | 108 | 0.011 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.011 | |
| regeneration | GO:0031099 | 4 | 0.011 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 131 | 0.011 | |
| maintenance of location in cell | GO:0051651 | 62 | 0.011 | |
| maintenance of protein localization in organelle | GO:0072595 | 15 | 0.011 | |
| maintenance of protein location in cell | GO:0032507 | 56 | 0.011 | |
| superoxide metabolic process | GO:0006801 | 20 | 0.011 | |
| positive regulation of systemic arterial blood pressure | GO:0003084 | 2 | 0.011 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.011 | |
| multicellular organism reproduction | GO:0032504 | 42 | 0.011 | |
| regulation of intracellular transport | GO:0032386 | 195 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 85 | 0.011 | |
| response to hydrogen peroxide | GO:0042542 | 40 | 0.010 | |
| negative regulation of cellular response to growth factor stimulus | GO:0090288 | 41 | 0.010 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.010 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.010 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 41 | 0.010 | |
| glycogen metabolic process | GO:0005977 | 22 | 0.010 | |
| neural nucleus development | GO:0048857 | 47 | 0.010 | |
| aging | GO:0007568 | 66 | 0.010 | |
| positive regulation of multicellular organism growth | GO:0040018 | 6 | 0.010 | |
| purine containing compound biosynthetic process | GO:0072522 | 88 | 0.010 | |
| reproductive structure development | GO:0048608 | 55 | 0.010 | |
