Homo sapiens

0 known processes

PDIA4

protein disulfide isomerase family A, member 4

(Aliases: ERP72,ERP70,ERp-72)

PDIA4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein foldingGO:0006457380.999
Yeast Rat
chaperone mediated protein foldingGO:0061077130.998
Rat
response to unfolded proteinGO:0006986240.961
Worm
response to topologically incorrect proteinGO:0035966290.629
Worm
endoplasmic reticulum unfolded protein responseGO:0030968160.621
Worm
cellular amino acid metabolic processGO:00065201160.597
cellular response to topologically incorrect proteinGO:0035967190.568
Worm
4 hydroxyproline metabolic processGO:001947150.513
negative regulation of sequestering of calcium ionGO:0051283410.428
regulation of behaviorGO:0050795820.371
response to endoplasmic reticulum stressGO:0034976490.367
Worm
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.344
oxidation reduction processGO:00551143960.340
Yeast
cellular modified amino acid metabolic processGO:0006575640.334
cellular response to unfolded proteinGO:0034620160.332
Worm
er nucleus signaling pathwayGO:0006984230.307
Worm
alpha amino acid metabolic processGO:1901605720.291
sequestering of metal ionGO:0051238240.280
protein hydroxylationGO:001812690.256
post embryonic developmentGO:000979120.234
positive regulation of cell motilityGO:20001471770.212
sleepGO:003043120.182
response to hypoxiaGO:0001666960.173
response to decreased oxygen levelsGO:0036293960.168
negative regulation of apoptotic processGO:00430663160.167
cardiovascular system developmentGO:00723582620.159
cellular amine metabolic processGO:0044106410.151
actin filament based processGO:00300292240.151
cell chemotaxisGO:00603261120.151
de novo protein foldingGO:000645820.150
regulation of sequestering of calcium ionGO:0051282410.144
posttranscriptional regulation of gene expressionGO:00106082130.142
response to oxygen containing compoundGO:19017003690.140
protein stabilizationGO:0050821640.140
positive regulation of cellular component organizationGO:00511303760.140
peptidyl tyrosine phosphorylationGO:00181081700.135
intrinsic apoptotic signaling pathwayGO:00971931270.131
startle responseGO:000196430.119
sequestering of calcium ionGO:0051208170.116
negative regulation of retinoic acid receptor signaling pathwayGO:004838740.114
response to abiotic stimulusGO:00096283360.110
protein glycosylationGO:0006486620.109
lipid localizationGO:00108761060.108
positive regulation of developmental growthGO:0048639160.106
Worm
regulation of protein stabilityGO:0031647870.104
cellular homeostasisGO:00197251960.102
divalent metal ion transportGO:00708381520.101
determination of adult lifespanGO:000834020.097
dephosphorylationGO:00163112090.095
positive regulation of chemotaxisGO:0050921570.093
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.093
response to oxygen levelsGO:00704821000.090
positive regulation of cell deathGO:00109422630.089
vesicle mediated transportGO:00161923710.089
system processGO:00030083490.088
actin cytoskeleton organizationGO:00300362070.087
glycoprotein biosynthetic processGO:0009101910.086
positive regulation of developmental processGO:00510943140.085
Worm
positive regulation of programmed cell deathGO:00430682490.084
regulation of cell motilityGO:20001452990.084
regulation of cellular amino acid metabolic processGO:000652160.080
cytokinesisGO:0000910960.080
regulation of apoptotic signaling pathwayGO:20012331750.079
apoptotic signaling pathwayGO:00971902680.077
regulation of chemotaxisGO:0050920740.075
positive regulation of cytosolic calcium ion concentrationGO:0007204820.074
calcium ion transportGO:00068161470.073
cellular response to transforming growth factor beta stimulusGO:0071560940.071
peptidyl proline modificationGO:0018208150.067
locomotory behaviorGO:000762610.067
positive regulation of dna metabolic processGO:0051054730.066
chaperone mediated protein folding requiring cofactorGO:005108510.066
regulation of proteolysisGO:00301622930.065
protein maturationGO:00516042330.062
cellular cation homeostasisGO:00300031630.061
regulation of growthGO:00400081650.060
Worm
positive regulation of phosphorylationGO:00423273940.059
cellular response to decreased oxygen levelsGO:0036294510.055
positive regulation of apoptotic processGO:00430652460.055
regulation of ion homeostasisGO:2000021730.054
positive regulation of blood pressureGO:004577730.054
cytoplasmic transportGO:00164823790.053
cellular response to external stimulusGO:00714961110.051
central nervous system developmentGO:00074171230.050
proteasomal protein catabolic processGO:00104981760.049
hindbrain developmentGO:003090230.049
cellular ketone metabolic processGO:0042180800.048
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.047
male genitalia developmentGO:003053910.047
regulation of wnt protein secretionGO:006135610.046
glycosylationGO:0070085710.045
nervous system developmentGO:00073992930.044
regulation of developmental growthGO:0048638300.043
Worm
brain morphogenesisGO:004885410.042
regulation of cellular amine metabolic processGO:0033238110.042
cytosolic calcium ion transportGO:0060401480.041
monocarboxylic acid metabolic processGO:00327871850.041
cellular response to hypoxiaGO:0071456510.040
ubiquitin dependent protein catabolic processGO:00065112060.040
regulation of response to external stimulusGO:00321012220.040
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.040
cellular response to oxygen levelsGO:0071453550.040
cellular response to organonitrogen compoundGO:00714171240.040
positive regulation of multicellular organism growthGO:004001860.039
Worm
positive regulation of cell proliferationGO:00082843010.039
regulation of locomotionGO:00400123290.039
single organism membrane organizationGO:00448022680.038
regulation of cell migrationGO:00303342890.038
cellular calcium ion homeostasisGO:00068741170.037
neurological system process involved in regulation of systemic arterial blood pressureGO:000197620.037
regulation of homeostatic processGO:00328441210.037
response to transforming growth factor betaGO:0071559940.037
protein n linked glycosylationGO:0006487230.036
maintenance of locationGO:00512351120.036
heart developmentGO:0007507950.036
peptidyl tyrosine modificationGO:00182121700.035
peptidyl proline hydroxylation to 4 hydroxy l prolineGO:001840140.035
regulation of meiotic cell cycleGO:005144540.034
regulation of protein secretionGO:0050708860.034
negative regulation of protein metabolic processGO:00512483910.034
regulation of cell adhesionGO:00301551660.033
cytosolic calcium ion homeostasisGO:0051480890.033
antigen processing and presentationGO:0019882330.033
negative regulation of cellular protein metabolic processGO:00322693530.033
regulation of multi organism processGO:00439001570.032
regulation of response to oxidative stressGO:1902882260.032
circulatory system developmentGO:00723592620.032
growthGO:00400072020.031
Worm
positive regulation of growthGO:0045927580.031
Worm
small molecule catabolic processGO:0044282920.031
regulation of i kappab kinase nf kappab signalingGO:00431221620.031
regulation of vesicle mediated transportGO:00606271300.030
cellular response to growth factor stimulusGO:00713631970.030
cellular response to lithium ionGO:007128520.029
cellular divalent inorganic cation homeostasisGO:00725031280.029
cellular response to endogenous stimulusGO:00714953360.029
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.029
negative regulation of homeostatic processGO:0032845590.029
regulation of cell cycleGO:00517263930.029
cell substrate junction assemblyGO:0007044350.029
proteolysis involved in cellular protein catabolic processGO:00516032440.028
er associated ubiquitin dependent protein catabolic processGO:0030433310.027
positive regulation of response to external stimulusGO:0032103880.027
cellular metal ion homeostasisGO:00068751460.027
intracellular steroid hormone receptor signaling pathwayGO:0030518610.027
positive regulation of transportGO:00510503360.026
neurological system processGO:00508771630.026
calcium ion transport into cytosolGO:0060402480.026
regulation of dna metabolic processGO:00510521530.026
negative regulation of programmed cell deathGO:00430693210.026
divalent inorganic cation transportGO:00725111580.026
de novo posttranslational protein foldingGO:005108420.026
release of sequestered calcium ion into cytosolGO:0051209410.026
positive regulation of systemic arterial blood pressureGO:000308420.025
developmental growthGO:0048589480.025
Worm
extracellular structure organizationGO:0043062410.025
ion homeostasisGO:00508012300.025
cellular ion homeostasisGO:00068731680.025
purine nucleoside catabolic processGO:00061523980.025
chemotaxisGO:00069351570.025
cellular protein catabolic processGO:00442572610.025
oocyte developmentGO:004859910.024
response to lithium ionGO:001022620.024
regulation of cell substrate adhesionGO:0010810680.024
dna replicationGO:00062601160.024
negative regulation of cell cycleGO:00457861930.024
regulation of dna replicationGO:0006275680.024
regulation of cellular component movementGO:00512703340.023
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.023
metencephalon developmentGO:002203720.023
regulation of cellular ketone metabolic processGO:0010565500.023
regulation of cell developmentGO:00602841610.023
cellular macromolecular complex assemblyGO:00346223240.023
cell agingGO:0007569520.023
metal ion homeostasisGO:00550651690.022
cardiac muscle tissue developmentGO:0048738390.022
cell morphogenesisGO:00009022960.022
regulation of leukocyte chemotaxisGO:0002688460.022
synaptic vesicle endocytosisGO:004848820.022
positive regulation of hydrolase activityGO:00513453310.022
dopaminergic neuron differentiationGO:007154210.022
protein catabolic processGO:00301633250.022
regulation of protein kinase activityGO:00458592890.021
calcium ion homeostasisGO:00550741220.021
regulation of oxidative stress induced cell deathGO:1903201240.021
muscle cell differentiationGO:0042692630.021
divalent inorganic cation homeostasisGO:00725071360.021
cell cycle arrestGO:0007050710.021
negative regulation of phosphate metabolic processGO:00459362670.021
head developmentGO:00603221080.021
cell junction assemblyGO:0034329670.020
reactive oxygen species metabolic processGO:0072593750.020
regulation of peptidase activityGO:00525471800.020
translationGO:00064121320.020
protein homooligomerizationGO:00512601000.020
protein ubiquitinationGO:00165673140.019
cellular response to dna damage stimulusGO:00069743790.019
oocyte differentiationGO:000999420.019
regulation of cell cycle processGO:00105642660.019
extrinsic apoptotic signaling pathwayGO:00971911190.019
vasoconstrictionGO:0042310110.019
reproductionGO:0000003630.019
Worm
response to fungusGO:000962040.019
negative regulation of catalytic activityGO:00430863350.019
post embryonic organ developmentGO:004856910.019
cellular response to oxidative stressGO:0034599850.019
monocyte activationGO:004211730.019
modification dependent macromolecule catabolic processGO:00436322120.019
positive regulation of dna replicationGO:0045740350.019
positive regulation of cell adhesionGO:0045785840.019
transforming growth factor beta receptor signaling pathwayGO:0007179760.019
peptidyl asparagine modificationGO:0018196110.019
regulation of anatomical structure morphogenesisGO:00226032860.019
circulatory system processGO:00030131130.018
response to oxidative stressGO:00069791210.018
glycoprotein metabolic processGO:00091001100.018
intracellular receptor signaling pathwayGO:00305221040.018
regulation of protein modification by small protein conjugation or removalGO:19033201070.018
regulation of cell differentiationGO:00455953930.018
regulation of protein localizationGO:00328802960.018
rna interferenceGO:001624640.018
regulation of mitotic cell cycleGO:00073461890.018
cellular component morphogenesisGO:00329893140.018
multicellular organismal agingGO:001025930.018
modification dependent protein catabolic processGO:00199412090.017
regulation of kinase activityGO:00435493140.017
regulation of meiosisGO:004002030.017
leukocyte chemotaxisGO:0030595760.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
regulation of bindingGO:00510981110.017
regulation of cysteine type endopeptidase activityGO:20001161270.017
response to nitrogen compoundGO:19016981840.017
positive regulation of cell migrationGO:00303351720.017
positive regulation of cellular amine metabolic processGO:003324070.017
cellular protein complex assemblyGO:00436231880.017
response to organic cyclic compoundGO:00140702040.017
response to growth factorGO:00708482050.017
carbohydrate metabolic processGO:00059752070.017
positive regulation of embryonic developmentGO:004001960.017
neuron differentiationGO:00301821380.017
regulation of cell morphogenesisGO:00226041530.017
behaviorGO:00076101120.016
single organism cellular localizationGO:19025803320.016
positive regulation of kinase activityGO:00336742040.016
regulation of endocytosisGO:0030100720.016
genitalia morphogenesisGO:003511210.016
response to testosteroneGO:003357410.016
ribonucleotide catabolic processGO:00092614050.016
negative regulation of translationGO:0017148370.016
multi organism reproductive processGO:0044703540.016
dendritic cell migrationGO:003633660.016
nucleocytoplasmic transportGO:00069131760.016
sensory perception of smellGO:000760820.016
regulation of translationGO:0006417890.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
cation transportGO:00068123310.015
regulation of cellular response to stressGO:00801352440.015
cellular response to hormone stimulusGO:00328701250.015
protein oligomerizationGO:00512591730.015
regulation of dephosphorylationGO:0035303960.015
positive regulation of intracellular transportGO:00323881040.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
single organism cell adhesionGO:00986021790.015
positive regulation of proteolysisGO:00458621420.015
reactive oxygen species biosynthetic processGO:190340940.015
protein modification by small protein conjugationGO:00324463420.015
response to organonitrogen compoundGO:00102431560.015
cell morphogenesis involved in differentiationGO:00009041440.015
regenerationGO:003109940.015
protein maturation by protein foldingGO:002241720.015
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.015
response to glucagonGO:003376210.014
regulation of cellular component biogenesisGO:00440872810.014
response to hormoneGO:00097251750.014
positive regulation of secretionGO:00510471160.014
generation of neuronsGO:00486991520.014
positive regulation of apoptotic signaling pathwayGO:2001235700.014
visual behaviorGO:000763220.014
negative regulation of cell differentiationGO:00455961710.014
extracellular matrix organizationGO:0030198410.014
membrane organizationGO:00610242920.014
response to steroid hormoneGO:0048545800.014
regulation of cell divisionGO:00513021160.014
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:1902175160.013
endomembrane system organizationGO:00102561960.013
endocytosisGO:00068971590.013
response to axon injuryGO:004867810.013
brain developmentGO:0007420970.013
positive regulation of protein kinase activityGO:00458601900.013
tissue homeostasisGO:0001894630.013
pattern specification processGO:0007389430.013
regulation of purine nucleotide catabolic processGO:00331212050.013
actin filament organizationGO:00070151280.013
negative regulation of growthGO:0045926970.013
bone developmentGO:0060348260.013
regulation of lymphocyte chemotaxisGO:1901623120.013
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.013
organ morphogenesisGO:00098871470.013
regulation of blood vessel sizeGO:0050880180.012
regulation of phosphatase activityGO:0010921810.012
cell adhesionGO:00071553250.012
mitotic cell cycle phase transitionGO:00447721620.012
regulation of protein catabolic processGO:00421761550.012
cellular response to toxic substanceGO:009723740.012
nucleotide catabolic processGO:00091664080.012
segmentationGO:003528240.012
cellular response to metal ionGO:0071248430.012
neutrophil migrationGO:1990266250.012
agingGO:0007568660.011
reactive nitrogen species metabolic processGO:200105730.011
maintenance of protein localization in organelleGO:0072595150.011
positive regulation of immune system processGO:00026842830.011
cerebral cortex radially oriented cell migrationGO:002179910.011
response to starvationGO:0042594590.011
signal releaseGO:0023061700.011
positive regulation of nucleotide catabolic processGO:00308131850.011
response to toxic substanceGO:0009636370.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.011
response to extracellular stimulusGO:0009991850.011
cellular response to oxygen containing compoundGO:19017012760.011
regulation of multicellular organism growthGO:004001480.011
Worm
cellular macromolecule catabolic processGO:00442653800.011
positive regulation of endocytosisGO:0045807420.011
mitochondrion organizationGO:00070051560.011
response to estradiolGO:0032355230.011
regulation of phagocytosisGO:0050764210.011
organophosphate ester transportGO:0015748320.010
multicellular organismal reproductive processGO:0048609400.010
regulation of purine nucleotide metabolic processGO:19005422640.010
peptide cross linkingGO:0018149120.010
response to inorganic substanceGO:00100351270.010
regulation of collagen catabolic processGO:001071030.010
negative regulation of catabolic processGO:00098951040.010

PDIA4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
osteogenesis imperfectaDOID:12347130.811
musculoskeletal system diseaseDOID:172230.811
connective tissue diseaseDOID:651090.811
bone development diseaseDOID:0080006550.811
bone diseaseDOID:0080001880.811
osteochondrodysplasiaDOID:2256350.811
disease of cellular proliferationDOID:145661740.050
organ system cancerDOID:00506861640.041
cancerDOID:1621670.041
disease of metabolismDOID:00146672950.027
inherited metabolic disorderDOID:6552420.027
nervous system diseaseDOID:8634310.025
neurodegenerative diseaseDOID:12891020.025
central nervous system diseaseDOID:3311860.025
disease of mental healthDOID:150700.017
bone marrow cancerDOID:4960100.016
immune system cancerDOID:0060083360.016
myelomaDOID:007000470.016
hematologic cancerDOID:2531360.016