Homo sapiens

135 known processes

PCSK9

proprotein convertase subtilisin/kexin type 9

(Aliases: PC9,FH3,HCHOLA3,NARC1,LDLCQ1,NARC-1)

PCSK9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glycerolipid catabolic processGO:0046503180.180
transmembrane transportGO:00550853990.160
lipid catabolic processGO:0016042840.145
amine metabolic processGO:0009308440.137
anion transportGO:00068201610.131
cellular amine metabolic processGO:0044106410.128
cellular lipid catabolic processGO:0044242650.120
regulation of cellular amine metabolic processGO:0033238110.117
organophosphate ester transportGO:0015748320.111
organic anion transportGO:00157111030.100
chemical homeostasisGO:00488783060.098
response to glucagonGO:003376210.096
cholesterol homeostasisGO:0042632280.085
post embryonic developmentGO:000979120.085
response to organic cyclic compoundGO:00140702040.083
regulation of plasma lipoprotein particle levelsGO:0097006320.082
organophosphate catabolic processGO:00464344300.080
intestinal cholesterol absorptionGO:003029940.078
small molecule catabolic processGO:0044282920.077
regulation of cellular ketone metabolic processGO:0010565500.075
organic hydroxy compound transportGO:0015850630.070
vesicle mediated transportGO:00161923710.069
plasma lipoprotein particle clearanceGO:0034381160.067
phospholipid catabolic processGO:0009395120.064
regulation of lipid catabolic processGO:0050994230.064
lipid transportGO:0006869900.063
cellular biogenic amine metabolic processGO:0006576340.063
lipid metabolic processGO:00066293810.062
cellular lipid metabolic processGO:00442553030.062
protein catabolic processGO:00301633250.060
response to oxygen containing compoundGO:19017003690.058
phospholipid transportGO:0015914230.057
regulation of cellular amino acid metabolic processGO:000652160.057
steroid metabolic processGO:0008202940.056
response to lipidGO:00339932060.054
regulation of triglyceride metabolic processGO:0090207110.052
system processGO:00030083490.051
cellular amino acid metabolic processGO:00065201160.049
sterol homeostasisGO:0055092280.047
triglyceride biosynthetic processGO:0019432100.045
organic hydroxy compound metabolic processGO:19016151470.044
digestionGO:0007586220.044
lipoprotein metabolic processGO:0042157420.043
response to nitrogen compoundGO:19016981840.040
intestinal absorptionGO:005089240.040
acylglycerol metabolic processGO:0006639270.039
multicellular organismal agingGO:001025930.039
acylglycerol biosynthetic processGO:0046463110.039
cation transportGO:00068123310.039
positive regulation of triglyceride biosynthetic processGO:001086740.038
cardiovascular system developmentGO:00723582620.038
neutral lipid metabolic processGO:0006638270.038
determination of adult lifespanGO:000834020.038
phospholipid metabolic processGO:0006644990.038
single organism cellular localizationGO:19025803320.037
phosphatidylcholine catabolic processGO:003463830.037
nervous system developmentGO:00073992930.036
defense responseGO:00069523150.036
regulation of cell differentiationGO:00455953930.036
hindbrain developmentGO:003090230.036
glycerophospholipid metabolic processGO:0006650840.036
regulation of homeostatic processGO:00328441210.035
cell morphogenesisGO:00009022960.035
positive regulation of phosphorylationGO:00423273940.035
lipid localizationGO:00108761060.035
glycerolipid biosynthetic processGO:0045017510.034
regulation of sequence specific dna binding transcription factor activityGO:00510902110.034
ion transmembrane transportGO:00342203380.034
ion homeostasisGO:00508012300.033
negative regulation of cellular protein metabolic processGO:00322693530.033
oogenesisGO:004847720.033
ras protein signal transductionGO:0007265730.033
regulation of cell cycleGO:00517263930.032
phosphatidylcholine metabolic processGO:0046470190.032
cholesterol transportGO:0030301390.032
lipid biosynthetic processGO:00086101770.032
cytokine productionGO:00018162470.032
positive regulation of hydrolase activityGO:00513453310.032
cellular component morphogenesisGO:00329893140.031
small gtpase mediated signal transductionGO:0007264780.031
female gamete generationGO:000729220.031
glycerophospholipid catabolic processGO:004647560.031
regulation of anatomical structure morphogenesisGO:00226032860.031
actin filament based processGO:00300292240.031
cation transmembrane transportGO:00986552380.031
digestive system processGO:0022600170.030
response to abiotic stimulusGO:00096283360.030
negative regulation of catalytic activityGO:00430863350.030
regulation of protein localizationGO:00328802960.030
response to organonitrogen compoundGO:00102431560.030
lipid homeostasisGO:0055088390.029
cellular macromolecule catabolic processGO:00442653800.029
cytoplasmic transportGO:00164823790.029
regulation of transferase activityGO:00513383550.029
segmentationGO:003528240.029
sterol transportGO:0015918390.029
response to hormoneGO:00097251750.029
response to estrogenGO:0043627470.029
regulation of kinase activityGO:00435493140.029
negative regulation of protein metabolic processGO:00512483910.029
regulation of purine nucleotide metabolic processGO:19005422640.028
response to hypoxiaGO:0001666960.028
cellular homeostasisGO:00197251960.028
signal transduction by phosphorylationGO:00230142970.028
purine ribonucleoside metabolic processGO:00461284370.028
glycerolipid metabolic processGO:00464861070.028
dephosphorylationGO:00163112090.028
negative regulation of cell proliferationGO:00082852280.027
neuron fate commitmentGO:004866320.027
nucleoside phosphate catabolic processGO:19012924120.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
regulation of cholesterol homeostasisGO:200018820.027
negative regulation of programmed cell deathGO:00430693210.027
positive regulation of catabolic processGO:00098963100.027
negative regulation of cell deathGO:00605483450.027
response to steroid hormoneGO:0048545800.027
regulation of establishment of protein localizationGO:00702012420.027
response to decreased oxygen levelsGO:0036293960.027
positive regulation of cellular component organizationGO:00511303760.027
cell projection organizationGO:00300302520.027
negative regulation of multicellular organismal processGO:00512413170.026
alcohol metabolic processGO:00060661140.026
negative regulation of cellular component organizationGO:00511292350.026
rho protein signal transductionGO:0007266260.026
low density lipoprotein particle clearanceGO:003438380.026
epithelium developmentGO:00604292270.026
cation homeostasisGO:00550801890.026
cellular response to dna damage stimulusGO:00069743790.026
organic hydroxy compound catabolic processGO:1901616220.026
regulation of nucleotide metabolic processGO:00061402690.026
ribonucleoside catabolic processGO:00424544060.026
inorganic cation transmembrane transportGO:00986621940.026
positive regulation of apoptotic processGO:00430652460.025
purine nucleotide catabolic processGO:00061954050.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
forebrain regionalizationGO:002187130.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
nucleoside triphosphate metabolic processGO:00091414220.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
inorganic ion transmembrane transportGO:00986602310.025
glycosyl compound catabolic processGO:19016584130.024
regulation of cell motilityGO:20001452990.024
regulation of response to external stimulusGO:00321012220.024
regulation of protein transportGO:00512232130.024
regulation of cellular component biogenesisGO:00440872810.024
circulatory system developmentGO:00723592620.024
regulation of cell migrationGO:00303342890.024
purine containing compound catabolic processGO:00725234110.024
positive regulation of nucleotide metabolic processGO:00459812300.024
regulation of cytokine productionGO:00018172320.024
mapk cascadeGO:00001652880.024
purine ribonucleoside catabolic processGO:00461303980.024
locomotory behaviorGO:000762610.023
ribonucleotide catabolic processGO:00092614050.023
regulation of lipid metabolic processGO:0019216960.023
purine nucleoside catabolic processGO:00061523980.023
positive regulation of cell proliferationGO:00082843010.023
mitotic cell cycleGO:00002783260.023
endomembrane system organizationGO:00102561960.023
cell fate determinationGO:000170930.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
regulation of locomotionGO:00400123290.023
blood vessel developmentGO:00015681720.022
positive regulation of triglyceride metabolic processGO:009020890.022
negative regulation of developmental processGO:00510932470.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
nitrogen compound transportGO:00717051910.022
copulationGO:000762010.022
protein processingGO:00164852260.022
nucleotide catabolic processGO:00091664080.022
immune responseGO:00069553070.022
adult locomotory behaviorGO:000834410.022
neuromuscular junction developmentGO:000752830.022
cellular response to cytokine stimulusGO:00713451810.022
peripheral nervous system developmentGO:000742220.022
anterior posterior axis specificationGO:000994820.022
regulation of secretionGO:00510461940.022
spinal cord developmentGO:002151040.022
inner ear morphogenesisGO:004247240.022
nucleoside triphosphate catabolic processGO:00091433940.021
response to cytokineGO:00340972320.021
morphogenesis of embryonic epitheliumGO:001633140.021
response to external biotic stimulusGO:00432072610.021
cellular response to nitrogen compoundGO:19016991440.021
carboxylic acid biosynthetic processGO:0046394970.021
innate immune responseGO:00450871780.021
positive regulation of cell deathGO:00109422630.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
negative regulation of cellular amine metabolic processGO:003323930.021
response to alcoholGO:0097305640.021
positive regulation of lipid biosynthetic processGO:0046889220.021
positive regulation of cellular amine metabolic processGO:003324070.021
positive regulation of lipid metabolic processGO:0045834500.021
positive regulation of cellular catabolic processGO:00313312840.021
metal ion homeostasisGO:00550651690.021
epidermis morphogenesisGO:004873030.021
secretion by cellGO:00329402260.021
regulation of protein kinase activityGO:00458592890.021
monocarboxylic acid metabolic processGO:00327871850.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
positive regulation of programmed cell deathGO:00430682490.021
cellular ketone metabolic processGO:0042180800.021
membrane organizationGO:00610242920.020
organophosphate biosynthetic processGO:00904071630.020
negative regulation of cell differentiationGO:00455961710.020
vasculature developmentGO:00019441810.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
neutral lipid biosynthetic processGO:0046460110.020
apoptotic signaling pathwayGO:00971902680.020
g protein coupled receptor signaling pathwayGO:00071862070.020
organ formationGO:004864530.020
positive regulation of transportGO:00510503360.020
regulation of immune responseGO:00507762010.020
cholesterol importGO:007050840.019
response to oxygen levelsGO:00704821000.019
forebrain generation of neuronsGO:002187230.019
positive regulation of immune system processGO:00026842830.019
secretionGO:00469032540.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
positive regulation of protein phosphorylationGO:00019343130.019
negative regulation of protein modification processGO:00314002000.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
nucleoside catabolic processGO:00091644080.019
cellular divalent inorganic cation homeostasisGO:00725031280.018
specification of organ identityGO:001009230.018
regulation of proteolysisGO:00301622930.018
cell developmentGO:00484683280.018
cellular response to growth factor stimulusGO:00713631970.018
memoryGO:000761330.018
response to other organismGO:00517072610.018
rhythmic behaviorGO:000762220.018
protein localization to membraneGO:00726571600.018
regenerationGO:003109940.018
response to biotic stimulusGO:00096072760.018
cellular ion homeostasisGO:00068731680.018
neurogenesisGO:00220081690.018
embryonic epithelial tube formationGO:000183840.017
ameboidal type cell migrationGO:00016671350.017
protein ubiquitinationGO:00165673140.017
mitotic cell cycle processGO:19030472860.017
epithelial cell differentiationGO:00308551410.017
regulation of cell cycle processGO:00105642660.017
tissue migrationGO:00901301190.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
response to peptide hormoneGO:0043434610.017
blastoderm segmentationGO:000735020.017
menstrual cycle phaseGO:002260120.017
photoreceptor cell differentiationGO:004653020.017
reactive oxygen species biosynthetic processGO:190340940.017
epithelial cell proliferationGO:00506731280.017
microtubule based processGO:00070172100.017
positive regulation of protein kinase activityGO:00458601900.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
immune system developmentGO:00025201950.017
posttranscriptional regulation of gene expressionGO:00106082130.017
regulation of protein secretionGO:0050708860.017
carbohydrate derivative transportGO:1901264200.017
monocarboxylic acid biosynthetic processGO:0072330670.017
extraocular skeletal muscle developmentGO:000207410.016
reactive oxygen species metabolic processGO:0072593750.016
negative regulation of cell cycleGO:00457861930.016
positive regulation of secretionGO:00510471160.016
spermatid differentiationGO:004851540.016
oxidation reduction processGO:00551143960.016
cellular response to organonitrogen compoundGO:00714171240.016
protein maturationGO:00516042330.016
cellular metal ion homeostasisGO:00068751460.016
single organism cell adhesionGO:00986021790.016
single organism membrane organizationGO:00448022680.016
protein modification by small protein conjugationGO:00324463420.016
establishment of protein localization to membraneGO:00901501210.016
cellular macromolecular complex assemblyGO:00346223240.016
negative regulation of phosphorus metabolic processGO:00105632670.016
negative regulation of phosphorylationGO:00423261740.016
endocytosisGO:00068971590.016
compound eye developmentGO:004874910.016
intracellular protein transportGO:00068862700.016
plasma membrane organizationGO:00070091150.016
cellular protein catabolic processGO:00442572610.016
biological adhesionGO:00226103310.016
regulation of triglyceride biosynthetic processGO:001086650.016
somitogenesisGO:000175620.016
metencephalon developmentGO:002203720.016
embryo developmentGO:00097901230.016
regulation of hormone levelsGO:00108171250.016
angiogenesisGO:00015251470.016
motor neuron axon guidanceGO:000804520.016
cholesterol metabolic processGO:0008203280.016
regulation of nucleoside metabolic processGO:00091182090.016
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
protein localization to organelleGO:00333652800.015
positive regulation of cellular component biogenesisGO:00440891580.015
atp metabolic processGO:00460341760.015
positive regulation of secretion by cellGO:19035321080.015
regulation of mitotic cell cycleGO:00073461890.015
metal ion transportGO:00300012720.015
immune effector processGO:00022521590.015
fatty acid metabolic processGO:00066311150.015
circadian behaviorGO:004851220.015
organic acid biosynthetic processGO:0016053970.015
calcium ion homeostasisGO:00550741220.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
positive regulation of cytokine productionGO:00018191670.015
syncytium formation by plasma membrane fusionGO:000076820.015
regulation of cytoskeleton organizationGO:00514931770.015
tissue regenerationGO:004224630.015
negative regulation of hydrolase activityGO:00513461820.015
cellular chemical homeostasisGO:00550821800.015
guanosine containing compound catabolic processGO:19010692390.015
regulation of protein serine threonine kinase activityGO:00719001790.015
cerebellum developmentGO:002154920.015
matingGO:000761810.015
response to fungusGO:000962040.015
guanosine containing compound metabolic processGO:19010682440.015
positive regulation of nucleotide catabolic processGO:00308131850.015
actin cytoskeleton organizationGO:00300362070.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
positive regulation of kinase activityGO:00336742040.014
regulation of growthGO:00400081650.014
sequestering of metal ionGO:0051238240.014
epithelial tube branching involved in lung morphogenesisGO:006044140.014
oocyte developmentGO:004859910.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
negative regulation of protein processingGO:00109551420.014
regulation of secretion by cellGO:19035301770.014
cellular response to oxygen containing compoundGO:19017012760.014
organonitrogen compound biosynthetic processGO:19015662000.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of defense responseGO:00313471540.014
monovalent inorganic cation transportGO:00156721280.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
nerve developmentGO:002167540.014
receptor mediated endocytosisGO:0006898840.014
regulation of cell adhesionGO:00301551660.014
head developmentGO:00603221080.014
nucleoside phosphate biosynthetic processGO:19012931090.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
limbic system developmentGO:002176130.014
sterol importGO:003537640.014
regulation of cell growthGO:00015581350.014
negative regulation of transportGO:00510511760.014
protein secretionGO:0009306980.014
spermatid developmentGO:000728640.014
purine ribonucleotide catabolic processGO:00091544040.014
cell morphogenesis involved in differentiationGO:00009041440.014
hair follicle morphogenesisGO:003106920.014
regulation of intracellular transportGO:00323861950.014
regulation of purine nucleotide catabolic processGO:00331212050.014
divalent inorganic cation homeostasisGO:00725071360.014
carbohydrate derivative biosynthetic processGO:19011372070.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
regulation of peptidase activityGO:00525471800.014
positive regulation of aldosterone biosynthetic processGO:003234920.014
interspecies interaction between organismsGO:00444191560.014
neuron differentiationGO:00301821380.013
negative regulation of transferase activityGO:00513481240.013
cell projection assemblyGO:00300311260.013
neuroblast proliferationGO:000740540.013
cellular protein complex assemblyGO:00436231880.013
modification dependent protein catabolic processGO:00199412090.013
modification dependent macromolecule catabolic processGO:00436322120.013
hemopoiesisGO:00300971800.013
positive regulation of mapk cascadeGO:00434101900.013
nucleoside monophosphate metabolic processGO:00091231910.013
forebrain neuron differentiationGO:002187930.013
oocyte differentiationGO:000999420.013
actin filament organizationGO:00070151280.013
regulation of multi organism processGO:00439001570.013
regulation of dephosphorylationGO:0035303960.013
regulation of endopeptidase activityGO:00525481700.013
ubiquitin dependent protein catabolic processGO:00065112060.013
carboxylic acid transportGO:0046942630.013
protein targetingGO:00066051870.013
organelle assemblyGO:00709251760.013
multi organism cellular processGO:00447641560.013
response to axon injuryGO:004867810.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of nucleotide catabolic processGO:00308112050.013
anion transmembrane transportGO:0098656760.013
tripartite regional subdivisionGO:000735120.013
peptidyl tyrosine modificationGO:00182121700.013
organic acid transportGO:0015849650.013
hemostasisGO:0007599760.013
neural tube formationGO:000184130.013
cell cell signalingGO:00072671550.013
cell part morphogenesisGO:00329901370.013
proteasomal protein catabolic processGO:00104981760.013
response to radiationGO:00093141510.013
behaviorGO:00076101120.013
positive regulation of proteolysisGO:00458621420.013
gtp metabolic processGO:00460392390.013
cell fate commitment involved in pattern specificationGO:006058110.013
mitochondrion organizationGO:00070051560.013
coagulationGO:0050817780.013
positive regulation of organelle organizationGO:00106381950.013
single organism carbohydrate metabolic processGO:00447231930.013
positive regulation of cellular component movementGO:00512721810.013
cell adhesionGO:00071553250.013
regulation of cellular component movementGO:00512703340.013
glycoprotein metabolic processGO:00091001100.013
cellular cation homeostasisGO:00300031630.013
embryonic camera type eye developmentGO:003107620.013
reactive nitrogen species metabolic processGO:200105730.013
regulation of wnt signaling pathwayGO:00301111230.013
cell differentiation in spinal cordGO:002151510.013
positive regulation of cell migrationGO:00303351720.013
single organism reproductive processGO:0044702980.012
ribose phosphate biosynthetic processGO:0046390820.012
negative regulation of apoptotic processGO:00430663160.012
response to woundingGO:00096111680.012
visual behaviorGO:000763220.012
anterior posterior axis specification embryoGO:000859520.012
protein homooligomerizationGO:00512601000.012
protein oligomerizationGO:00512591730.012
negative regulation of protein phosphorylationGO:00019331400.012
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.012
regulation of gtpase activityGO:00430871800.012
cell divisionGO:00513011680.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
vasodilationGO:004231140.012
sex determinationGO:000753030.012
positive regulation of nucleoside metabolic processGO:00459791860.012
receptor metabolic processGO:0043112810.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
positive regulation of transferase activityGO:00513472270.012
chromatin organizationGO:00063253510.012
gtp catabolic processGO:00061842370.012
embryonic forelimb morphogenesisGO:003511540.012
regulation of nucleotide biosynthetic processGO:0030808500.012
peptidyl tyrosine phosphorylationGO:00181081700.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
cranial nerve developmentGO:002154540.012
maintenance of locationGO:00512351120.012
regulation of apoptotic signaling pathwayGO:20012331750.012
ventral spinal cord developmentGO:002151710.012
pituitary gland developmentGO:002198320.012
cellular response to organic cyclic compoundGO:00714071270.012
sulfur compound metabolic processGO:00067901010.012
regulation of cyclic nucleotide metabolic processGO:0030799630.012
positive regulation of protein transportGO:00512221350.012
regulation of gtp catabolic processGO:00331241800.012
regulation of response to woundingGO:19030341010.012
regulation of actin filament based processGO:00329701410.012
morphogenesis of a polarized epitheliumGO:000173830.012
regulation of cellular response to stressGO:00801352440.012
cellular response to hormone stimulusGO:00328701250.012
neuron projection developmentGO:00311751060.012
response to peptideGO:1901652650.012
positive regulation of cell cycleGO:00457871400.012
purine ribonucleotide biosynthetic processGO:0009152790.012
pharynx developmentGO:006046510.011
regulation of actin cytoskeleton organizationGO:00329561160.011
response to virusGO:00096151260.011
regulation of ion transportGO:00432691890.011
purine nucleotide biosynthetic processGO:0006164840.011
regulation of mapk cascadeGO:00434082620.011
thymus developmentGO:004853830.011
forelimb morphogenesisGO:003513640.011
negative regulation of intracellular signal transductionGO:19025321830.011
regulation of neural precursor cell proliferationGO:200017740.011
tube closureGO:006060630.011
embryonic morphogenesisGO:0048598850.011
establishment of protein localization to organelleGO:00725941720.011
cellular response to lipidGO:00713961270.011
carbohydrate metabolic processGO:00059752070.011
associative learningGO:000830610.011
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.011
negative regulation of testosterone biosynthetic processGO:200022510.011
endosomal transportGO:00161971290.011
sterol metabolic processGO:0016125280.011
regulation of lipid biosynthetic processGO:0046890470.011
actin mediated cell contractionGO:0070252120.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
negative regulation of response to external stimulusGO:0032102830.011
non canonical wnt signaling pathway via mapk cascadeGO:003803040.011
wnt signaling pathway involved in wound healing spreading of epidermal cellsGO:003565910.011

PCSK9 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.295
inherited metabolic disorderDOID:6552420.251
sensory system diseaseDOID:00501552030.031
nervous system diseaseDOID:8634310.031
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.020
musculoskeletal system diseaseDOID:172230.020
central nervous system diseaseDOID:3311860.015
connective tissue diseaseDOID:651090.015
bone diseaseDOID:0080001880.015
immune system diseaseDOID:29141550.015
cancerDOID:1621670.014
disease of cellular proliferationDOID:145661740.014
retinal diseaseDOID:56791180.014
organ system cancerDOID:00506861640.012
neurodegenerative diseaseDOID:12891020.011