Homo sapiens

0 known processes

IRX4

iroquois homeobox 4

(Aliases: MGC131996,IRXA3)

IRX4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organ morphogenesisGO:00098871470.628
Human Rat
anatomical structure formation involved in morphogenesisGO:00486462840.614
circulatory system developmentGO:00723592620.458
Mouse
renal system pattern specificationGO:007204810.414
positive regulation of cell proliferationGO:00082843010.403
regulation of locomotionGO:00400123290.400
cardiovascular system developmentGO:00723582620.353
Mouse
cell developmentGO:00484683280.282
Zebrafish
organ formationGO:004864530.273
regulation of cell differentiationGO:00455953930.268
tube developmentGO:00352951250.248
regulation of cell motilityGO:20001452990.241
epithelium developmentGO:00604292270.232
Zebrafish
regulation of cellular component movementGO:00512703340.229
cellular amine metabolic processGO:0044106410.228
negative regulation of multicellular organismal processGO:00512413170.225
regulation of cellular ketone metabolic processGO:0010565500.215
regulation of cellular amino acid metabolic processGO:000652160.215
system processGO:00030083490.214
cellular amino acid metabolic processGO:00065201160.209
neuron fate commitmentGO:004866320.192
skeletal system developmentGO:0001501790.185
Human
negative regulation of developmental processGO:00510932470.181
regulation of cellular amine metabolic processGO:0033238110.180
nervous system developmentGO:00073992930.180
Zebrafish
cell cell signalingGO:00072671550.174
amine metabolic processGO:0009308440.171
cellular ketone metabolic processGO:0042180800.167
embryonic morphogenesisGO:0048598850.162
Human
tissue morphogenesisGO:0048729960.156
positive regulation of cellular amine metabolic processGO:003324070.154
tube morphogenesisGO:0035239950.151
regulation of cell migrationGO:00303342890.150
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.150
transmembrane transportGO:00550853990.149
small gtpase mediated signal transductionGO:0007264780.148
post embryonic developmentGO:000979120.148
morphogenesis of embryonic epitheliumGO:001633140.141
morphogenesis of an epitheliumGO:0002009600.133
segmentationGO:003528240.131
epidermis morphogenesisGO:004873030.126
epithelial cell differentiationGO:00308551410.125
Zebrafish
cellular response to endogenous stimulusGO:00714953360.125
ion transmembrane transportGO:00342203380.119
forebrain regionalizationGO:002187130.119
regulation of anatomical structure morphogenesisGO:00226032860.115
hindbrain developmentGO:003090230.114
specification of organ identityGO:001009230.112
positive regulation of tooth mineralizationGO:007017220.112
digestive tract developmentGO:0048565750.110
ion homeostasisGO:00508012300.109
ras protein signal transductionGO:0007265730.108
hair follicle morphogenesisGO:003106920.107
extraocular skeletal muscle developmentGO:000207410.106
cardiac cell fate determinationGO:006091330.104
positive regulation of cellular amino acid metabolic processGO:004576430.101
vasculature developmentGO:00019441810.097
cellular component morphogenesisGO:00329893140.094
negative regulation of locomotionGO:00400131180.093
blood vessel developmentGO:00015681720.093
head developmentGO:00603221080.090
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.089
negative regulation of cell deathGO:00605483450.084
response to oxygen containing compoundGO:19017003690.084
forelimb morphogenesisGO:003513640.083
negative regulation of cell differentiationGO:00455961710.081
negative regulation of programmed cell deathGO:00430693210.081
embryonic forelimb morphogenesisGO:003511540.081
spinal cord developmentGO:002151040.079
ribonucleoside triphosphate catabolic processGO:00092033910.078
negative regulation of cellular component movementGO:00512711060.078
epidermis developmentGO:0008544590.076
Zebrafish
epithelial cell migrationGO:00106311190.076
enzyme linked receptor protein signaling pathwayGO:00071673030.075
regulation of cell cycleGO:00517263930.075
positive regulation of developmental processGO:00510943140.075
embryonic epithelial tube formationGO:000183840.074
actin filament based processGO:00300292240.073
cell morphogenesisGO:00009022960.073
central nervous system developmentGO:00074171230.073
cell projection organizationGO:00300302520.073
negative regulation of apoptotic processGO:00430663160.072
purine containing compound catabolic processGO:00725234110.071
cellular response to oxygen containing compoundGO:19017012760.070
purine nucleoside catabolic processGO:00061523980.070
cell morphogenesis involved in differentiationGO:00009041440.070
positive regulation of phosphorylationGO:00423273940.069
nucleoside triphosphate metabolic processGO:00091414220.069
brain developmentGO:0007420970.069
purine nucleotide catabolic processGO:00061954050.068
cell fate determinationGO:000170930.068
chemotaxisGO:00069351570.068
nucleoside phosphate catabolic processGO:19012924120.068
secretionGO:00469032540.068
cardiac muscle cell contractionGO:008600340.068
organic hydroxy compound metabolic processGO:19016151470.067
positive regulation of transportGO:00510503360.067
negative regulation of protein metabolic processGO:00512483910.067
negative regulation of cell migrationGO:00303361020.066
regulation of cell developmentGO:00602841610.066
organophosphate catabolic processGO:00464344300.066
nucleoside catabolic processGO:00091644080.065
positive regulation of programmed cell deathGO:00430682490.065
inner ear morphogenesisGO:004247240.065
heart developmentGO:0007507950.064
Mouse
urogenital system developmentGO:0001655650.064
skin developmentGO:0043588760.064
Zebrafish
neurogenesisGO:00220081690.063
Zebrafish
ribonucleotide catabolic processGO:00092614050.063
cytoplasmic transportGO:00164823790.063
inorganic ion transmembrane transportGO:00986602310.063
rho protein signal transductionGO:0007266260.062
positive regulation of protein phosphorylationGO:00019343130.062
chemical homeostasisGO:00488783060.061
positive regulation of hydrolase activityGO:00513453310.061
single organism cellular localizationGO:19025803320.061
nucleoside triphosphate catabolic processGO:00091433940.060
immune system developmentGO:00025201950.060
cell adhesionGO:00071553250.060
response to lipidGO:00339932060.058
lipid metabolic processGO:00066293810.058
signal transduction by phosphorylationGO:00230142970.057
nerve developmentGO:002167540.057
heart morphogenesisGO:0003007480.057
negative regulation of cellular protein metabolic processGO:00322693530.057
positive regulation of apoptotic processGO:00430652460.056
ribonucleoside triphosphate metabolic processGO:00091994120.056
positive regulation of cell differentiationGO:00455972110.056
forebrain generation of neuronsGO:002187230.056
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.055
negative regulation of cell motilityGO:20001461040.055
purine nucleoside triphosphate catabolic processGO:00091463920.055
muscle structure developmentGO:0061061980.055
purine nucleoside triphosphate metabolic processGO:00091444120.055
glycosyl compound catabolic processGO:19016584130.055
cellular response to cytokine stimulusGO:00713451810.055
positive regulation of cellular component organizationGO:00511303760.055
tissue migrationGO:00901301190.054
cellular response to growth factor stimulusGO:00713631970.054
ameboidal type cell migrationGO:00016671350.054
g protein coupled receptor signaling pathwayGO:00071862070.054
biological adhesionGO:00226103310.053
mapk cascadeGO:00001652880.053
cation transmembrane transportGO:00986552380.053
response to hormoneGO:00097251750.053
response to cytokineGO:00340972320.053
purine ribonucleoside triphosphate metabolic processGO:00092054110.052
hematopoietic or lymphoid organ developmentGO:00485341860.052
taxisGO:00423301570.052
blood vessel morphogenesisGO:00485141620.052
small molecule biosynthetic processGO:00442831570.052
ribonucleoside catabolic processGO:00424544060.051
digestive system developmentGO:0055123750.051
positive regulation of cellular component movementGO:00512721810.051
positive regulation of cell deathGO:00109422630.051
heart formationGO:006091420.051
forebrain developmentGO:0030900260.050
immune responseGO:00069553070.049
membrane organizationGO:00610242920.049
purine ribonucleoside catabolic processGO:00461303980.049
positive regulation of odontogenesisGO:004248230.049
peptidyl tyrosine modificationGO:00182121700.049
negative regulation of cellular component organizationGO:00511292350.049
negative regulation of cell proliferationGO:00082852280.049
hair cycleGO:0042633280.049
positive regulation of epithelial cell proliferationGO:0050679650.048
positive regulation of catabolic processGO:00098963100.048
regulation of system processGO:00440571010.048
cell activationGO:00017752130.048
regulation of mapk cascadeGO:00434082620.047
response to organic cyclic compoundGO:00140702040.047
generation of neuronsGO:00486991520.047
Zebrafish
regenerationGO:003109940.046
cranial nerve developmentGO:002154540.046
somatic stem cell maintenanceGO:003501940.046
purine ribonucleoside metabolic processGO:00461284370.046
positive regulation of cell motilityGO:20001471770.046
regulation of protein localizationGO:00328802960.046
oxidative stress induced premature senescenceGO:009040330.045
response to growth factorGO:00708482050.045
cation transportGO:00068123310.045
positive regulation of cell migrationGO:00303351720.045
regulation of hormone levelsGO:00108171250.045
secretion by cellGO:00329402260.045
purine ribonucleotide catabolic processGO:00091544040.045
positive regulation of nucleotide metabolic processGO:00459812300.045
protein localization to membraneGO:00726571600.044
multicellular organismal agingGO:001025930.044
cardiac muscle contractionGO:0060048340.044
regulation of cellular component biogenesisGO:00440872810.043
actin mediated cell contractionGO:0070252120.043
nucleotide catabolic processGO:00091664080.043
blood circulationGO:00080151130.043
positive regulation of locomotionGO:00400171860.043
response to biotic stimulusGO:00096072760.043
regulation of protein transportGO:00512232130.042
purine ribonucleoside triphosphate catabolic processGO:00092073910.042
regulation of transferase activityGO:00513383550.042
keratinizationGO:003142420.042
epidermal cell differentiationGO:0009913450.042
Zebrafish
positive regulation of cellular catabolic processGO:00313312840.042
single organism cell adhesionGO:00986021790.042
regulation of actin filament based processGO:00329701410.042
regulation of purine nucleotide catabolic processGO:00331212050.041
vesicle mediated transportGO:00161923710.041
response to nitrogen compoundGO:19016981840.041
regulation of secretion by cellGO:19035301770.041
muscle tissue developmentGO:0060537620.041
cellular lipid metabolic processGO:00442553030.040
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.040
inorganic cation transmembrane transportGO:00986621940.040
neuron differentiationGO:00301821380.040
Zebrafish
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.040
circulatory system processGO:00030131130.039
regulation of establishment of protein localizationGO:00702012420.039
copulationGO:000762010.039
limbic system developmentGO:002176130.039
muscle system processGO:0003012810.039
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.039
regulation of nucleotide metabolic processGO:00061402690.039
cytokine productionGO:00018162470.039
response to abiotic stimulusGO:00096283360.038
positive regulation of mapk cascadeGO:00434101900.038
renal system developmentGO:0072001630.038
kidney developmentGO:0001822530.038
embryo developmentGO:00097901230.038
Human
stem cell differentiationGO:0048863930.038
endomembrane system organizationGO:00102561960.038
female gamete generationGO:000729220.038
regulation of small gtpase mediated signal transductionGO:00510561560.038
regulation of ras protein signal transductionGO:00465781550.038
embryonic camera type eye developmentGO:003107620.038
outflow tract septum morphogenesisGO:000314840.038
gtp metabolic processGO:00460392390.037
anion transportGO:00068201610.037
cellular response to dna damage stimulusGO:00069743790.037
response to woundingGO:00096111680.037
wnt signaling pathwayGO:00160551560.037
organonitrogen compound biosynthetic processGO:19015662000.037
actin filament based movementGO:0030048170.037
regulation of cellular response to stressGO:00801352440.037
defense responseGO:00069523150.037
angiogenesisGO:00015251470.037
negative regulation of catalytic activityGO:00430863350.037
protein maturationGO:00516042330.036
wound healingGO:00420601150.036
plasma membrane organizationGO:00070091150.036
positive regulation of nucleotide catabolic processGO:00308131850.036
regulation of protein kinase activityGO:00458592890.036
apoptotic signaling pathwayGO:00971902680.035
intracellular protein transportGO:00068862700.035
regulation of gtpase activityGO:00430871800.035
epithelial cell proliferationGO:00506731280.035
cell differentiation in spinal cordGO:002151510.035
glycine importGO:003623310.035
monocarboxylic acid metabolic processGO:00327871850.035
mitotic cell cycleGO:00002783260.035
regulation of muscle system processGO:0090257530.035
guanosine containing compound catabolic processGO:19010692390.035
reproductive processGO:00224141060.035
Human
positive regulation of cell cycleGO:00457871400.035
cell proliferation in forebrainGO:002184610.034
lipid biosynthetic processGO:00086101770.034
striated muscle tissue developmentGO:0014706590.034
regulation of epithelial cell proliferationGO:00506781130.034
actin cytoskeleton organizationGO:00300362070.034
cd8 positive alpha beta t cell differentiation involved in immune responseGO:000230210.034
androgen biosynthetic processGO:000670230.034
hemopoiesisGO:00300971800.033
regulation of kinase activityGO:00435493140.033
sensory organ morphogenesisGO:0090596210.033
regulation of proteolysisGO:00301622930.033
response to external biotic stimulusGO:00432072610.033
single organism membrane organizationGO:00448022680.033
oogenesisGO:004847720.033
canonical wnt signaling pathwayGO:00600701160.033
kidney epithelium developmentGO:0072073250.033
nephron epithelium developmentGO:0072009230.033
regulation of secretionGO:00510461940.033
regulation of response to external stimulusGO:00321012220.033
cardiac muscle tissue developmentGO:0048738390.033
regulation of nucleoside metabolic processGO:00091182090.032
positive regulation of nucleoside metabolic processGO:00459791860.032
behaviorGO:00076101120.032
chordate embryonic developmentGO:0043009340.032
Human
positive regulation of purine nucleotide metabolic processGO:19005442270.032
guanosine containing compound metabolic processGO:19010682440.032
regulation of cell cycle processGO:00105642660.032
determination of adult lifespanGO:000834020.032
nitrogen compound transportGO:00717051910.032
regulation of purine nucleotide metabolic processGO:19005422640.032
endothelial cell migrationGO:0043542860.032
metencephalon developmentGO:002203720.032
regulation of neurogenesisGO:0050767820.031
muscle contractionGO:0006936730.031
embryonic organ developmentGO:0048568360.031
Human
negative regulation of phosphate metabolic processGO:00459362670.031
anterior posterior axis specificationGO:000994820.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.031
protein processingGO:00164852260.031
neuron projection developmentGO:00311751060.031
regulation of cytokine productionGO:00018172320.031
sensory organ developmentGO:0007423520.030
Zebrafish
gtp catabolic processGO:00061842370.030
pattern specification processGO:0007389430.030
Rat
prostate gland developmentGO:003085030.030
serotonin uptakeGO:005161020.030
neural tube formationGO:000184130.030
cellular macromolecular complex assemblyGO:00346223240.030
matingGO:000761810.030
positive regulation of gtpase activityGO:00435471660.030
reactive oxygen species metabolic processGO:0072593750.030
regulation of cell adhesionGO:00301551660.030
positive regulation of purine nucleotide catabolic processGO:00331231850.030
epithelial tube morphogenesisGO:0060562380.030
hormone secretionGO:0046879650.030
positive regulation of cell developmentGO:0010720920.030
carbohydrate derivative biosynthetic processGO:19011372070.029
cell fate commitmentGO:0045165270.029
peripheral nervous system developmentGO:000742220.029
Zebrafish
cellular response to organonitrogen compoundGO:00714171240.029
negative regulation of phosphorus metabolic processGO:00105632670.029
regulation of peptidase activityGO:00525471800.029
regulation of endopeptidase activityGO:00525481700.029
mesonephric duct developmentGO:007217730.029
epithelium migrationGO:00901321190.029
peptidyl tyrosine phosphorylationGO:00181081700.029
regulation of male gonad developmentGO:200001840.029
regulation of nervous system developmentGO:0051960880.029
regulation of nucleotide catabolic processGO:00308112050.029
blastoderm segmentationGO:000735020.029
striated muscle contractionGO:0006941520.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.028
positive regulation of aldosterone metabolic processGO:003234620.028
negative regulation of cell cycleGO:00457861930.028
regionalizationGO:0003002290.028
lymphocyte activationGO:00466491330.028
growthGO:00400072020.028
single organism reproductive processGO:0044702980.028
Human
catagenGO:004263730.028
cell substrate adhesionGO:00315891320.028
response to inorganic substanceGO:00100351270.028
chromatin organizationGO:00063253510.028
protein localization to plasma membraneGO:0072659930.028
establishment of protein localization to membraneGO:00901501210.028
metal ion transportGO:00300012720.028
thymus developmentGO:004853830.027
single organismal cell cell adhesionGO:00163371480.027
endocrine system developmentGO:0035270260.027
regulation of body fluid levelsGO:0050878990.027
oxidation reduction processGO:00551143960.027
intracellular receptor signaling pathwayGO:00305221040.027
memoryGO:000761330.027
positive regulation of dermatome developmentGO:006118430.027
posttranscriptional regulation of gene expressionGO:00106082130.027
compound eye developmentGO:004874910.027
response to other organismGO:00517072610.027
regulation of growthGO:00400081650.027
regulation of mitotic cell cycleGO:00073461890.027
regulation of gtp catabolic processGO:00331241800.027
positive regulation of protein kinase activityGO:00458601900.026
sex determinationGO:000753030.026
regulation of peptidyl tyrosine phosphorylationGO:00507301080.026
kidney morphogenesisGO:0060993190.026
chromatin modificationGO:00165682980.026
regulation of stem cell differentiationGO:2000736560.026
motor neuron axon guidanceGO:000804520.026
regulation of ion homeostasisGO:2000021730.026
leukocyte activationGO:00453211640.026
cerebellum developmentGO:002154920.026
positive regulation of secretionGO:00510471160.026
cartilage condensationGO:000150210.026
regulation of apoptotic signaling pathwayGO:20012331750.026
positive regulation of cortisol biosynthetic processGO:200006610.026
forebrain neuron differentiationGO:002187930.026
glial cell migrationGO:000834740.026
cellular chemical homeostasisGO:00550821800.026
regulation of ras gtpase activityGO:00323181280.025
forebrain dorsal ventral pattern formationGO:002179810.025
protein localization to organelleGO:00333652800.025
cell junction organizationGO:0034330790.025
paramesonephric duct developmentGO:006120520.025
dermatome developmentGO:006105430.025
positive regulation of cytokine productionGO:00018191670.025
cell type specific apoptotic processGO:00972851250.025
positive regulation of kinase activityGO:00336742040.025
hindlimb morphogenesisGO:003513720.025
locomotory behaviorGO:000762610.025
tissue regenerationGO:004224630.024
establishment of protein localization to plasma membraneGO:0090002680.024
positive regulation of immune system processGO:00026842830.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
positive regulation of secretion by cellGO:19035321080.024
ossificationGO:00015031210.024
cation homeostasisGO:00550801890.024
cell growthGO:00160491600.024
negative regulation of cellular amine metabolic processGO:003323930.024
erk1 and erk2 cascadeGO:00703711040.024
embryonic camera type eye formationGO:006090020.024
cellular response to nitrogen compoundGO:19016991440.024
positive regulation of cell adhesionGO:0045785840.024
regulation of response to woundingGO:19030341010.024
immune effector processGO:00022521590.024
cardiac right ventricle morphogenesisGO:000321530.024
cell part morphogenesisGO:00329901370.024
cellular macromolecule catabolic processGO:00442653800.024
cell divisionGO:00513011680.023
aortic valve developmentGO:000317630.023
serotonin transportGO:000683730.023
soft palate developmentGO:006002330.023
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.023
skeletal system morphogenesisGO:0048705240.023
Human
regulation of lipid metabolic processGO:0019216960.023
protein catabolic processGO:00301633250.023
metal ion homeostasisGO:00550651690.023
alcohol metabolic processGO:00060661140.023
negative regulation of transportGO:00510511760.023
testosterone biosynthetic processGO:006137020.023
mesenchyme developmentGO:0060485590.023
regulation of cytoskeleton organizationGO:00514931770.023
organic anion transportGO:00157111030.023
positive regulation of glucocorticoid biosynthetic processGO:003194810.023
positive regulation of ras gtpase activityGO:00323201170.023
synaptic transmission glycinergicGO:006001210.023
regulation of cell divisionGO:00513021160.023
muscle organ developmentGO:0007517560.023
jnk cascadeGO:0007254800.023
primary neural tube formationGO:001402030.023
keratinocyte differentiationGO:0030216360.023
neuroendocrine cell differentiationGO:006110120.022
regulation of ion transportGO:00432691890.022
neuron developmentGO:00486661130.022
Zebrafish
regulation of cell morphogenesisGO:00226041530.022
negative regulation of protein phosphorylationGO:00019331400.022
nephron tubule formationGO:007207910.022
cloacal septationGO:006019710.022
negative regulation of phosphorylationGO:00423261740.022
positive regulation of neural precursor cell proliferationGO:200017920.022
negative regulation of protein modification processGO:00314002000.022
regulation of axon guidanceGO:190266730.022
response to organonitrogen compoundGO:00102431560.022
somitogenesisGO:000175620.022
cellular response to lipidGO:00713961270.022
reactive oxygen species biosynthetic processGO:190340940.022
positive regulation of transferase activityGO:00513472270.022
action potentialGO:0001508340.022
cell projection morphogenesisGO:00488581290.022
muscle cell differentiationGO:0042692630.021
cellular response to hormone stimulusGO:00328701250.021
regulation of cell growthGO:00015581350.021
pituitary gland developmentGO:002198320.021
organic hydroxy compound biosynthetic processGO:1901617710.021
positive regulation of organelle organizationGO:00106381950.021
cellular response to organic cyclic compoundGO:00714071270.021
organophosphate biosynthetic processGO:00904071630.021
regulation of neural precursor cell proliferationGO:200017740.021
pattern specification involved in kidney developmentGO:006100410.021
mesodermal cell fate specificationGO:000750120.021
regulation of muscle contractionGO:0006937450.021
protein oligomerizationGO:00512591730.021
neural tube patterningGO:002153220.021
response to metal ionGO:0010038840.021
innate immune responseGO:00450871780.021
regulation of intracellular transportGO:00323861950.020
regulation of reactive oxygen species metabolic processGO:2000377410.020
histone modificationGO:00165702510.020
regulation of dermatome developmentGO:006118330.020
anion transmembrane transportGO:0098656760.020
regulation of striated muscle contractionGO:0006942370.020
positive regulation of proteolysisGO:00458621420.020
mesodermal cell fate commitmentGO:000171020.020
mitotic cell cycle processGO:19030472860.020
amide transportGO:0042886760.020
regulation of transporter activityGO:0032409820.020
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.020
neuroblast proliferationGO:000740540.020
neuromuscular junction developmentGO:000752830.020
neurological system processGO:00508771630.020
negative regulation of cell developmentGO:0010721480.020
cell aggregationGO:009874310.020
stress activated mapk cascadeGO:0051403930.020
positive regulation of gtp catabolic processGO:00331261660.020
rostrocaudal neural tube patterningGO:002190310.019
reactive nitrogen species metabolic processGO:200105730.019
covalent chromatin modificationGO:00165692540.019
fatty acid metabolic processGO:00066311150.019
heart field specificationGO:000312820.019

IRX4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.055
connective tissue diseaseDOID:651090.027
bone diseaseDOID:0080001880.027
disease of metabolismDOID:00146672950.026
central nervous system diseaseDOID:3311860.022
nervous system diseaseDOID:8634310.022
disease of cellular proliferationDOID:145661740.020