Homo sapiens

0 known processes

IRX3

iroquois homeobox 3

(Aliases: FLJ99187,IRX-1,IRXB1)

IRX3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.083
cellular amine metabolic processGO:0044106410.082
cellular ketone metabolic processGO:0042180800.082
post embryonic developmentGO:000979120.080
Worm
regulation of cellular amine metabolic processGO:0033238110.077
amine metabolic processGO:0009308440.074
regulation of cellular ketone metabolic processGO:0010565500.068
regulation of cellular amino acid metabolic processGO:000652160.060
positive regulation of cellular amino acid metabolic processGO:004576430.058
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.057
positive regulation of cellular amine metabolic processGO:003324070.054
cell developmentGO:00484683280.046
Mouse
segmentationGO:003528240.046
Mouse
system processGO:00030083490.045
regulation of cell differentiationGO:00455953930.045
Mouse
negative regulation of cell deathGO:00605483450.045
peripheral nervous system developmentGO:000742220.044
lipid metabolic processGO:00066293810.044
negative regulation of multicellular organismal processGO:00512413170.043
Mouse
response to oxygen containing compoundGO:19017003690.043
regulation of cellular component movementGO:00512703340.042
multicellular organismal agingGO:001025930.042
anatomical structure formation involved in morphogenesisGO:00486462840.042
Mouse
cellular component morphogenesisGO:00329893140.042
nervous system developmentGO:00073992930.042
Mouse
determination of adult lifespanGO:000834020.041
regulation of cell motilityGO:20001452990.040
morphogenesis of embryonic epitheliumGO:001633140.040
Mouse
negative regulation of apoptotic processGO:00430663160.039
hindbrain developmentGO:003090230.039
organ morphogenesisGO:00098871470.039
Human Mouse
negative regulation of developmental processGO:00510932470.039
Mouse
cell morphogenesisGO:00009022960.038
negative regulation of cell proliferationGO:00082852280.038
female gamete generationGO:000729220.038
cardiovascular system developmentGO:00723582620.038
regulation of cell cycleGO:00517263930.038
cell adhesionGO:00071553250.037
negative regulation of protein metabolic processGO:00512483910.037
positive regulation of developmental processGO:00510943140.037
Mouse
response to abiotic stimulusGO:00096283360.037
inner ear morphogenesisGO:004247240.037
positive regulation of hydrolase activityGO:00513453310.037
locomotory behaviorGO:000762610.036
negative regulation of cellular protein metabolic processGO:00322693530.036
positive regulation of programmed cell deathGO:00430682490.036
positive regulation of cell deathGO:00109422630.035
chemical homeostasisGO:00488783060.035
positive regulation of cellular component organizationGO:00511303760.035
cellular response to endogenous stimulusGO:00714953360.035
regulation of locomotionGO:00400123290.035
oogenesisGO:004847720.035
embryonic epithelial tube formationGO:000183840.035
Mouse
positive regulation of phosphorylationGO:00423273940.034
negative regulation of programmed cell deathGO:00430693210.034
secretionGO:00469032540.034
immune responseGO:00069553070.034
positive regulation of cell proliferationGO:00082843010.034
circulatory system developmentGO:00723592620.034
ras protein signal transductionGO:0007265730.032
cell fate determinationGO:000170930.032
neuron fate commitmentGO:004866320.032
positive regulation of apoptotic processGO:00430652460.032
mitotic cell cycleGO:00002783260.032
regulation of cell migrationGO:00303342890.032
cation transportGO:00068123310.032
enzyme linked receptor protein signaling pathwayGO:00071673030.032
regulation of proteolysisGO:00301622930.032
regulation of anatomical structure morphogenesisGO:00226032860.031
epithelium developmentGO:00604292270.031
Mouse
positive regulation of cell differentiationGO:00455972110.031
Mouse
biological adhesionGO:00226103310.031
blastoderm segmentationGO:000735020.031
transmembrane transportGO:00550853990.031
negative regulation of catalytic activityGO:00430863350.030
tissue morphogenesisGO:0048729960.030
Mouse
positive regulation of transportGO:00510503360.030
embryonic morphogenesisGO:0048598850.030
Human Zebrafish Mouse
purine containing compound catabolic processGO:00725234110.030
cytoplasmic transportGO:00164823790.030
cell projection organizationGO:00300302520.030
negative regulation of phosphorus metabolic processGO:00105632670.029
nucleoside triphosphate metabolic processGO:00091414220.029
cellular macromolecule catabolic processGO:00442653800.029
cellular lipid metabolic processGO:00442553030.029
actin filament based processGO:00300292240.029
nerve developmentGO:002167540.029
negative regulation of phosphate metabolic processGO:00459362670.029
defense responseGO:00069523150.029
cellular response to oxygen containing compoundGO:19017012760.028
vesicle mediated transportGO:00161923710.028
small gtpase mediated signal transductionGO:0007264780.028
response to lipidGO:00339932060.028
positive regulation of protein phosphorylationGO:00019343130.028
regenerationGO:003109940.028
regulation of protein localizationGO:00328802960.027
mapk cascadeGO:00001652880.027
organ formationGO:004864530.027
single organism cellular localizationGO:19025803320.027
cellular response to dna damage stimulusGO:00069743790.027
skeletal system developmentGO:0001501790.027
Human
glycosyl compound catabolic processGO:19016584130.027
purine ribonucleoside metabolic processGO:00461284370.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
protein catabolic processGO:00301633250.026
organophosphate catabolic processGO:00464344300.026
ribonucleoside catabolic processGO:00424544060.026
specification of organ identityGO:001009230.026
purine nucleoside catabolic processGO:00061523980.026
positive regulation of catabolic processGO:00098963100.026
regulation of kinase activityGO:00435493140.026
nucleoside triphosphate catabolic processGO:00091433940.026
neural crest cell developmentGO:001403230.026
embryonic forelimb morphogenesisGO:003511540.026
signal transduction by phosphorylationGO:00230142970.026
response to other organismGO:00517072610.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
purine ribonucleotide catabolic processGO:00091544040.026
neuromuscular junction developmentGO:000752830.025
regulation of transferase activityGO:00513383550.025
nucleoside catabolic processGO:00091644080.025
protein maturationGO:00516042330.025
ribonucleotide catabolic processGO:00092614050.025
nitrogen compound transportGO:00717051910.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
forelimb morphogenesisGO:003513640.025
secretion by cellGO:00329402260.025
regulation of protein kinase activityGO:00458592890.025
ribonucleoside triphosphate metabolic processGO:00091994120.025
purine ribonucleoside catabolic processGO:00461303980.025
purine nucleotide catabolic processGO:00061954050.025
negative regulation of cellular component organizationGO:00511292350.025
organonitrogen compound biosynthetic processGO:19015662000.025
oxidation reduction processGO:00551143960.024
regulation of secretionGO:00510461940.024
generation of neuronsGO:00486991520.024
Mouse
nucleoside phosphate catabolic processGO:19012924120.024
protein localization to organelleGO:00333652800.024
regulation of establishment of protein localizationGO:00702012420.024
photoreceptor cell differentiationGO:004653020.024
somatic stem cell maintenanceGO:003501940.024
anterior posterior axis specificationGO:000994820.024
ion homeostasisGO:00508012300.024
blood vessel developmentGO:00015681720.024
rho protein signal transductionGO:0007266260.023
regulation of nucleotide metabolic processGO:00061402690.023
growthGO:00400072020.023
regulation of cell developmentGO:00602841610.023
Mouse
regulation of response to external stimulusGO:00321012220.023
carbohydrate derivative biosynthetic processGO:19011372070.023
monocarboxylic acid metabolic processGO:00327871850.023
carbohydrate metabolic processGO:00059752070.023
positive regulation of immune system processGO:00026842830.023
purine nucleoside triphosphate catabolic processGO:00091463920.023
negative regulation of protein modification processGO:00314002000.023
regulation of endopeptidase activityGO:00525481700.023
negative regulation of cell cycleGO:00457861930.023
regulation of purine nucleotide metabolic processGO:19005422640.023
negative regulation of transportGO:00510511760.023
regulation of protein transportGO:00512232130.023
nucleotide catabolic processGO:00091664080.023
response to biotic stimulusGO:00096072760.022
positive regulation of cellular catabolic processGO:00313312840.022
single organism membrane organizationGO:00448022680.022
forebrain generation of neuronsGO:002187230.022
epithelial cell differentiationGO:00308551410.022
apoptotic signaling pathwayGO:00971902680.022
mitotic cell cycle processGO:19030472860.022
protein processingGO:00164852260.022
chemotaxisGO:00069351570.022
response to external biotic stimulusGO:00432072610.022
regulation of cell cycle processGO:00105642660.022
regulation of cellular response to stressGO:00801352440.022
dephosphorylationGO:00163112090.022
single organism carbohydrate metabolic processGO:00447231930.022
regulation of mapk cascadeGO:00434082620.022
cell morphogenesis involved in differentiationGO:00009041440.022
intracellular protein transportGO:00068862700.022
cation transmembrane transportGO:00986552380.022
regulation of cellular component biogenesisGO:00440872810.022
neural tube formationGO:000184130.022
ion transmembrane transportGO:00342203380.022
regulation of peptidase activityGO:00525471800.021
wnt signaling pathwayGO:00160551560.021
membrane organizationGO:00610242920.021
thymus developmentGO:004853830.021
cranial nerve developmentGO:002154540.021
regulation of cytokine productionGO:00018172320.021
negative regulation of cell differentiationGO:00455961710.021
Mouse
cellular protein catabolic processGO:00442572610.021
vasculature developmentGO:00019441810.021
protein modification by small protein conjugationGO:00324463420.021
cytokine productionGO:00018162470.021
memoryGO:000761330.021
neuroblast proliferationGO:000740540.021
regulation of mitotic cell cycleGO:00073461890.021
cellular macromolecular complex assemblyGO:00346223240.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
regulation of hormone levelsGO:00108171250.021
chromatin organizationGO:00063253510.021
metal ion transportGO:00300012720.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
sex determinationGO:000753030.021
negative regulation of cellular amine metabolic processGO:003323930.020
protein ubiquitinationGO:00165673140.020
response to woundingGO:00096111680.020
positive regulation of nucleotide metabolic processGO:00459812300.020
primary neural tube formationGO:001402030.020
neuron differentiationGO:00301821380.020
Mouse
negative regulation of cellular amino acid metabolic processGO:004576320.020
anterior posterior axis specification embryoGO:000859520.020
hematopoietic or lymphoid organ developmentGO:00485341860.020
cellular response to growth factor stimulusGO:00713631970.020
lipid biosynthetic processGO:00086101770.020
regulation of secretion by cellGO:19035301770.020
regulation of intracellular transportGO:00323861950.019
forebrain regionalizationGO:002187130.019
immune system developmentGO:00025201950.019
embryo developmentGO:00097901230.019
Human Zebrafish Mouse Worm
taxisGO:00423301570.019
cellular homeostasisGO:00197251960.019
positive regulation of transferase activityGO:00513472270.019
spermatid differentiationGO:004851540.019
maintenance of locationGO:00512351120.019
adult locomotory behaviorGO:000834410.019
innate immune responseGO:00450871780.019
negative regulation of intracellular signal transductionGO:19025321830.019
response to cytokineGO:00340972320.019
oocyte developmentGO:004859910.019
guanosine containing compound metabolic processGO:19010682440.019
head developmentGO:00603221080.019
pituitary gland developmentGO:002198320.019
cation homeostasisGO:00550801890.018
neurological system processGO:00508771630.018
tube closureGO:006060630.018
neurogenesisGO:00220081690.018
Mouse
rhythmic behaviorGO:000762220.018
tripartite regional subdivisionGO:000735120.018
motor neuron axon guidanceGO:000804520.018
organophosphate biosynthetic processGO:00904071630.018
regulation of growthGO:00400081650.018
negative regulation of hydrolase activityGO:00513461820.018
hemopoiesisGO:00300971800.018
cardiac muscle cell contractionGO:008600340.018
small molecule biosynthetic processGO:00442831570.018
gtp metabolic processGO:00460392390.018
metencephalon developmentGO:002203720.018
positive regulation of organelle organizationGO:00106381950.018
epithelial cell proliferationGO:00506731280.018
reactive oxygen species biosynthetic processGO:190340940.018
posttranscriptional regulation of gene expressionGO:00106082130.018
brain developmentGO:0007420970.018
reactive oxygen species metabolic processGO:0072593750.018
compound eye developmentGO:004874910.018
blood circulationGO:00080151130.018
positive regulation of mapk cascadeGO:00434101900.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
chromatin modificationGO:00165682980.018
response to organic cyclic compoundGO:00140702040.017
cellular response to cytokine stimulusGO:00713451810.017
positive regulation of synaptic transmissionGO:005080640.017
central nervous system developmentGO:00074171230.017
guanosine containing compound catabolic processGO:19010692390.017
oocyte differentiationGO:000999420.017
response to nitrogen compoundGO:19016981840.017
anion transportGO:00068201610.017
regulation of wnt signaling pathwayGO:00301111230.017
neurotransmitter secretionGO:000726940.017
positive regulation of proteolysisGO:00458621420.017
regulation of neural precursor cell proliferationGO:200017740.017
salivary gland morphogenesisGO:000743540.017
embryonic camera type eye developmentGO:003107620.017
limbic system developmentGO:002176130.017
negative regulation of phosphorylationGO:00423261740.017
negative regulation of cell migrationGO:00303361020.017
ossificationGO:00015031210.017
circadian behaviorGO:004851220.017
positive regulation of locomotionGO:00400171860.017
response to hormoneGO:00097251750.017
cell cell signalingGO:00072671550.017
Worm
spermatid developmentGO:000728640.017
positive regulation of cell motilityGO:20001471770.017
blood vessel morphogenesisGO:00485141620.017
actin cytoskeleton organizationGO:00300362070.017
inorganic ion transmembrane transportGO:00986602310.017
endomembrane system organizationGO:00102561960.017
cell activationGO:00017752130.017
histone modificationGO:00165702510.017
response to growth factorGO:00708482050.017
cell projection morphogenesisGO:00488581290.017
regulation of protein catabolic processGO:00421761550.017
regulation of protein maturationGO:19033171500.016
spinal cord developmentGO:002151040.016
morphogenesis of a polarized epitheliumGO:000173830.016
cell part morphogenesisGO:00329901370.016
positive regulation of kinase activityGO:00336742040.016
neural tube closureGO:000184330.016
angiogenesisGO:00015251470.016
regulation of synaptic plasticityGO:004816730.016
microtubule based processGO:00070172100.016
somitogenesisGO:000175620.016
canonical wnt signaling pathwayGO:00600701160.016
developmental programmed cell deathGO:001062330.016
neuron developmentGO:00486661130.016
reproductive processGO:00224141060.016
Human
endodermal cell fate commitmentGO:000171140.016
positive regulation of protein kinase activityGO:00458601900.016
nuclear transportGO:00511691790.016
positive regulation of cytokine productionGO:00018191670.016
regulation of nucleoside metabolic processGO:00091182090.016
actin mediated cell contractionGO:0070252120.016
positive regulation of cell cycleGO:00457871400.016
cell differentiation in spinal cordGO:002151510.016
gtp catabolic processGO:00061842370.016
cellular cation homeostasisGO:00300031630.016
positive regulation of nucleoside metabolic processGO:00459791860.016
covalent chromatin modificationGO:00165692540.016
positive regulation of cellular component movementGO:00512721810.016
cell divisionGO:00513011680.016
regulation of protein processingGO:00706131500.016
regulation of ion transportGO:00432691890.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
cell growthGO:00160491600.016
positive regulation of cell migrationGO:00303351720.016
response to organonitrogen compoundGO:00102431560.016
protein oligomerizationGO:00512591730.016
nucleocytoplasmic transportGO:00069131760.016
reactive nitrogen species metabolic processGO:200105730.016
regulation of cytoplasmic transportGO:19036491490.016
protein targetingGO:00066051870.016
circulatory system processGO:00030131130.016
regulation of immune responseGO:00507762010.016
regulation of apoptotic signaling pathwayGO:20012331750.015
cell cycle phase transitionGO:00447701730.015
regulation of cell adhesionGO:00301551660.015
regulation of purine nucleotide catabolic processGO:00331212050.015
positive regulation of secretion by cellGO:19035321080.015
epithelial tube branching involved in lung morphogenesisGO:006044140.015
metal ion homeostasisGO:00550651690.015
cell substrate adhesionGO:00315891320.015
positive regulation of protein transportGO:00512221350.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
tissue regenerationGO:004224630.015
regulation of nucleotide catabolic processGO:00308112050.015
cerebellum developmentGO:002154920.015
endodermal cell fate specificationGO:000171440.015
proteasomal protein catabolic processGO:00104981760.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
organic hydroxy compound metabolic processGO:19016151470.015
tube morphogenesisGO:0035239950.015
Zebrafish Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.015
negative regulation of immune system processGO:00026831360.015
positive regulation of cell developmentGO:0010720920.015
Mouse
mitotic cell cycle phase transitionGO:00447721620.015
fatty acid metabolic processGO:00066311150.015
inorganic cation transmembrane transportGO:00986621940.015
cardiac cell fate determinationGO:006091330.015
epithelium migrationGO:00901321190.015
matingGO:000761810.015
peptidyl tyrosine phosphorylationGO:00181081700.015
single organism cell adhesionGO:00986021790.015
divalent inorganic cation homeostasisGO:00725071360.015
regulation of male gonad developmentGO:200001840.015
negative regulation of protein maturationGO:19033181420.015
cellular response to lipidGO:00713961270.015
cellular metal ion homeostasisGO:00068751460.015
epithelial cell migrationGO:00106311190.014
regulation of ras protein signal transductionGO:00465781550.014
cellular chemical homeostasisGO:00550821800.014
response to fungusGO:000962040.014
actin filament based movementGO:0030048170.014
stem cell divisionGO:001714520.014
organic anion transportGO:00157111030.014
syncytium formation by plasma membrane fusionGO:000076820.014
divalent metal ion transportGO:00708381520.014
negative regulation of protein phosphorylationGO:00019331400.014
regulation of gtpase activityGO:00430871800.014
response to axon injuryGO:004867810.014
negative regulation of locomotionGO:00400131180.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
heart formationGO:006091420.014
single organism reproductive processGO:0044702980.014
Human
regulation of cytoskeleton organizationGO:00514931770.014
embryonic viscerocranium morphogenesisGO:004870310.014
negative regulation of protein processingGO:00109551420.014
protein localization to membraneGO:00726571600.014
positive regulation of nucleotide catabolic processGO:00308131850.014
sequestering of metal ionGO:0051238240.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
regulation of intracellular protein transportGO:00331571230.014
epidermis morphogenesisGO:004873030.014
regulation of dna metabolic processGO:00510521530.014
negative regulation of cell motilityGO:20001461040.014
modification dependent protein catabolic processGO:00199412090.014
heart developmentGO:0007507950.014
cellular ion homeostasisGO:00068731680.014
associative learningGO:000830610.014
positive regulation of gtp catabolic processGO:00331261660.014
modification dependent macromolecule catabolic processGO:00436322120.014
organelle assemblyGO:00709251760.014
ameboidal type cell migrationGO:00016671350.014
ubiquitin dependent protein catabolic processGO:00065112060.014
g protein coupled receptor signaling pathwayGO:00071862070.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of multi organism processGO:00439001570.014
regulation of gtp catabolic processGO:00331241800.014
positive regulation of gtpase activityGO:00435471660.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
visual behaviorGO:000763220.014
cellular response to nitrogen compoundGO:19016991440.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of body fluid levelsGO:0050878990.014
cell type specific apoptotic processGO:00972851250.014
glycoprotein metabolic processGO:00091001100.013
carboxylic acid biosynthetic processGO:0046394970.013
negative regulation of growthGO:0045926970.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
regulation of cell morphogenesisGO:00226041530.013
establishment of protein localization to organelleGO:00725941720.013
regulation of protein complex assemblyGO:00432541470.013
dna repairGO:00062811980.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
positive regulation of secretionGO:00510471160.013
cellular protein complex assemblyGO:00436231880.013
male genitalia developmentGO:003053910.013
regulation of homeostatic processGO:00328441210.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
forebrain neuron differentiationGO:002187930.013
divalent inorganic cation transportGO:00725111580.013
sequestering of calcium ionGO:0051208170.013
response to inorganic substanceGO:00100351270.013
nucleoside phosphate biosynthetic processGO:19012931090.013
regulation of cell growthGO:00015581350.013
regulation of epithelial cell proliferationGO:00506781130.013
regulation of system processGO:00440571010.013
regulation of cardiac muscle tissue growthGO:005502140.013
lung alveolus developmentGO:004828640.013
sensory perception of painGO:001923340.013
nucleotide biosynthetic processGO:00091651090.013
peptidyl tyrosine modificationGO:00182121700.013
myoblast fusionGO:000752010.013
negative regulation of gliogenesisGO:001401430.013
hindlimb morphogenesisGO:003513720.013
glial cell migrationGO:000834740.013
regulation of stem cell differentiationGO:2000736560.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
tube developmentGO:00352951250.013
Zebrafish Mouse
response to radiationGO:00093141510.013
negative regulation of cellular component movementGO:00512711060.013
regulation of protein serine threonine kinase activityGO:00719001790.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
embryonic organ developmentGO:0048568360.013
Human
tissue migrationGO:00901301190.013
rna processingGO:00063962550.013
axis elongationGO:000340140.013
microtubule cytoskeleton organizationGO:00002261760.013
wound healingGO:00420601150.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
negative regulation of proteolysisGO:00458611320.013
organic acid biosynthetic processGO:0016053970.013
peptidyl lysine modificationGO:00182051440.013
regulation of epithelial cell migrationGO:0010632930.013
regulation of vesicle mediated transportGO:00606271300.013
positive regulation of neural precursor cell proliferationGO:200017920.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
cell projection assemblyGO:00300311260.013
mitochondrion organizationGO:00070051560.013
protein acylationGO:00435431380.013
regulation of meiotic cell cycleGO:005144540.013
blastocyst developmentGO:000182430.012
nucleoside monophosphate metabolic processGO:00091231910.012
cellular response to organic cyclic compoundGO:00714071270.012
establishment or maintenance of bipolar cell polarityGO:006124520.012

IRX3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.039
disease of metabolismDOID:00146672950.026
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
connective tissue diseaseDOID:651090.022
bone diseaseDOID:0080001880.022
inherited metabolic disorderDOID:6552420.021
disease of cellular proliferationDOID:145661740.020
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
central nervous system diseaseDOID:3311860.019
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
immune system diseaseDOID:29141550.015
retinal diseaseDOID:56791180.014
muscular diseaseDOID:00800001140.013
muscle tissue diseaseDOID:661130.013
cardiovascular system diseaseDOID:12871060.013
bone development diseaseDOID:0080006550.013