Homo sapiens

0 known processes

PCSK4

proprotein convertase subtilisin/kexin type 4

(Aliases: SPC5,MGC34749,PC4,DKFZp434B217)

PCSK4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.076
regulation of cellular amine metabolic processGO:0033238110.073
cellular amino acid metabolic processGO:00065201160.065
positive regulation of catabolic processGO:00098963100.060
cellular ketone metabolic processGO:0042180800.060
regulation of cellular ketone metabolic processGO:0010565500.059
positive regulation of cellular amine metabolic processGO:003324070.058
transmembrane transportGO:00550853990.057
cellular amine metabolic processGO:0044106410.054
regulation of cellular amino acid metabolic processGO:000652160.054
ribonucleoside catabolic processGO:00424544060.051
positive regulation of phosphorylationGO:00423273940.050
amine metabolic processGO:0009308440.049
positive regulation of cellular amino acid metabolic processGO:004576430.046
organophosphate catabolic processGO:00464344300.045
system processGO:00030083490.045
Human
nucleotide catabolic processGO:00091664080.044
nucleoside triphosphate metabolic processGO:00091414220.044
determination of adult lifespanGO:000834020.043
positive regulation of protein phosphorylationGO:00019343130.042
purine ribonucleoside triphosphate metabolic processGO:00092054110.042
ion transmembrane transportGO:00342203380.041
purine ribonucleoside triphosphate catabolic processGO:00092073910.041
purine ribonucleoside metabolic processGO:00461284370.041
multicellular organismal agingGO:001025930.039
nucleoside phosphate catabolic processGO:19012924120.039
purine nucleoside triphosphate metabolic processGO:00091444120.039
female gamete generationGO:000729220.038
regulation of purine nucleotide metabolic processGO:19005422640.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
memoryGO:000761330.037
purine containing compound catabolic processGO:00725234110.037
ribonucleoside triphosphate metabolic processGO:00091994120.037
ras protein signal transductionGO:0007265730.036
glycosyl compound catabolic processGO:19016584130.036
single organism carbohydrate metabolic processGO:00447231930.036
nucleoside triphosphate catabolic processGO:00091433940.036
locomotory behaviorGO:000762610.036
purine ribonucleotide catabolic processGO:00091544040.035
regulation of nucleotide metabolic processGO:00061402690.035
oogenesisGO:004847720.034
positive regulation of transportGO:00510503360.034
ribonucleotide catabolic processGO:00092614050.034
purine nucleoside catabolic processGO:00061523980.034
cellular response to endogenous stimulusGO:00714953360.033
purine nucleotide catabolic processGO:00061954050.033
negative regulation of catalytic activityGO:00430863350.032
Human
ribonucleoside triphosphate catabolic processGO:00092033910.032
nervous system developmentGO:00073992930.032
Fly
positive regulation of cellular catabolic processGO:00313312840.031
purine ribonucleoside catabolic processGO:00461303980.031
cation transportGO:00068123310.031
membrane organizationGO:00610242920.031
regulation of nucleotide catabolic processGO:00308112050.031
carbohydrate metabolic processGO:00059752070.029
regulation of nucleoside metabolic processGO:00091182090.029
regulation of purine nucleotide catabolic processGO:00331212050.029
secretionGO:00469032540.028
Human
cellular lipid metabolic processGO:00442553030.028
small gtpase mediated signal transductionGO:0007264780.028
single organism membrane organizationGO:00448022680.027
single organism cellular localizationGO:19025803320.027
response to oxygen containing compoundGO:19017003690.027
lipid metabolic processGO:00066293810.027
ion homeostasisGO:00508012300.027
positive regulation of transferase activityGO:00513472270.026
mapk cascadeGO:00001652880.026
cation homeostasisGO:00550801890.025
cell developmentGO:00484683280.025
Fly
cytoplasmic transportGO:00164823790.025
cellular response to oxygen containing compoundGO:19017012760.025
positive regulation of nucleotide metabolic processGO:00459812300.024
protein maturationGO:00516042330.024
Human
monocarboxylic acid metabolic processGO:00327871850.024
cellular macromolecule catabolic processGO:00442653800.024
Human
negative regulation of phosphorus metabolic processGO:00105632670.024
regulation of protein kinase activityGO:00458592890.024
cell adhesionGO:00071553250.024
regulation of kinase activityGO:00435493140.024
response to hormoneGO:00097251750.023
nucleoside catabolic processGO:00091644080.023
positive regulation of cellular component organizationGO:00511303760.023
neurological system processGO:00508771630.023
vesicle mediated transportGO:00161923710.023
regulation of cellular component biogenesisGO:00440872810.022
neuromuscular junction developmentGO:000752830.022
negative regulation of protein metabolic processGO:00512483910.022
Human
positive regulation of nucleotide catabolic processGO:00308131850.022
regulation of transferase activityGO:00513383550.022
positive regulation of hydrolase activityGO:00513453310.021
negative regulation of transportGO:00510511760.021
positive regulation of purine nucleotide catabolic processGO:00331231850.021
negative regulation of phosphate metabolic processGO:00459362670.021
matingGO:000761810.021
protein processingGO:00164852260.021
Human
inorganic ion transmembrane transportGO:00986602310.021
oocyte differentiationGO:000999420.021
regulation of cellular response to stressGO:00801352440.020
positive regulation of kinase activityGO:00336742040.020
signal transduction by phosphorylationGO:00230142970.020
metal ion transportGO:00300012720.020
positive regulation of protein kinase activityGO:00458601900.020
anion transportGO:00068201610.020
negative regulation of cellular protein metabolic processGO:00322693530.020
Human
negative regulation of cellular component organizationGO:00511292350.020
epithelium developmentGO:00604292270.020
regulation of gtpase activityGO:00430871800.020
protein localization to organelleGO:00333652800.020
regenerationGO:003109940.019
positive regulation of nucleoside metabolic processGO:00459791860.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
lipid biosynthetic processGO:00086101770.019
regulation of protein serine threonine kinase activityGO:00719001790.019
defense responseGO:00069523150.019
cellular response to dna damage stimulusGO:00069743790.019
regulation of cell cycleGO:00517263930.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
guanosine containing compound metabolic processGO:19010682440.019
gtp catabolic processGO:00061842370.019
mitotic cell cycleGO:00002783260.019
positive regulation of cell motilityGO:20001471770.019
cell morphogenesisGO:00009022960.019
spermatid differentiationGO:004851540.019
endomembrane system organizationGO:00102561960.019
organic acid biosynthetic processGO:0016053970.018
regulation of cellular component movementGO:00512703340.018
dephosphorylationGO:00163112090.018
segmentationGO:003528240.018
immune responseGO:00069553070.018
negative regulation of programmed cell deathGO:00430693210.018
negative regulation of hydrolase activityGO:00513461820.018
Human
regulation of gtp catabolic processGO:00331241800.018
associative learningGO:000830610.018
protein localization to membraneGO:00726571600.018
monovalent inorganic cation transportGO:00156721280.018
regulation of cell migrationGO:00303342890.018
gtp metabolic processGO:00460392390.018
nucleoside monophosphate metabolic processGO:00091231910.018
negative regulation of cellular amine metabolic processGO:003323930.018
cellular homeostasisGO:00197251960.018
oocyte developmentGO:004859910.018
apoptotic signaling pathwayGO:00971902680.018
guanosine containing compound catabolic processGO:19010692390.018
regulation of cell motilityGO:20001452990.017
atp metabolic processGO:00460341760.017
negative regulation of multicellular organismal processGO:00512413170.017
Human
protein catabolic processGO:00301633250.017
Human
photoreceptor cell differentiationGO:004653020.017
regulation of transmembrane transporter activityGO:0022898740.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
response to organic cyclic compoundGO:00140702040.017
organ morphogenesisGO:00098871470.017
maintenance of locationGO:00512351120.017
neuron differentiationGO:00301821380.017
Fly
biological adhesionGO:00226103310.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of immune system processGO:00026842830.017
regulation of cell cycle processGO:00105642660.017
response to lipidGO:00339932060.017
morphogenesis of embryonic epitheliumGO:001633140.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
cellular ion homeostasisGO:00068731680.017
mitotic cell cycle processGO:19030472860.017
regulation of dna metabolic processGO:00510521530.017
response to abiotic stimulusGO:00096283360.017
cation transmembrane transportGO:00986552380.016
oxidation reduction processGO:00551143960.016
positive regulation of cell differentiationGO:00455972110.016
peptidyl tyrosine modificationGO:00182121700.016
small molecule biosynthetic processGO:00442831570.016
protein oligomerizationGO:00512591730.016
cellular component morphogenesisGO:00329893140.016
adult locomotory behaviorGO:000834410.016
cell projection organizationGO:00300302520.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
regulation of protein localizationGO:00328802960.016
regulation of proteolysisGO:00301622930.016
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of transmembrane transportGO:00347621390.016
chemical homeostasisGO:00488783060.016
glycoprotein metabolic processGO:00091001100.016
Human
regulation of ion transportGO:00432691890.016
regulation of transporter activityGO:0032409820.016
cellular protein catabolic processGO:00442572610.016
Human
positive regulation of cellular component movementGO:00512721810.016
positive regulation of gtpase activityGO:00435471660.015
metal ion homeostasisGO:00550651690.015
response to external biotic stimulusGO:00432072610.015
positive regulation of cell proliferationGO:00082843010.015
regulation of mapk cascadeGO:00434082620.015
sleepGO:003043120.015
anterior posterior axis specificationGO:000994820.015
regulation of cell differentiationGO:00455953930.015
cellular metal ion homeostasisGO:00068751460.015
positive regulation of protein serine threonine kinase activityGO:00719021190.015
response to growth factorGO:00708482050.015
intracellular protein transportGO:00068862700.015
reactive oxygen species metabolic processGO:0072593750.015
cellular chemical homeostasisGO:00550821800.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
carboxylic acid biosynthetic processGO:0046394970.015
circulatory system processGO:00030131130.015
Human
peptidyl tyrosine phosphorylationGO:00181081700.015
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.015
innate immune responseGO:00450871780.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of anatomical structure morphogenesisGO:00226032860.014
spermatid developmentGO:000728640.014
carbohydrate derivative biosynthetic processGO:19011372070.014
positive regulation of developmental processGO:00510943140.014
sequestering of metal ionGO:0051238240.014
peripheral nervous system developmentGO:000742220.014
organonitrogen compound biosynthetic processGO:19015662000.014
Human
regulation of synaptic plasticityGO:004816730.014
blastoderm segmentationGO:000735020.014
divalent inorganic cation transportGO:00725111580.014
organophosphate biosynthetic processGO:00904071630.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
phospholipid metabolic processGO:0006644990.014
activation of protein kinase activityGO:0032147900.014
microtubule based processGO:00070172100.014
behaviorGO:00076101120.014
negative regulation of cell deathGO:00605483450.014
cellular response to growth factor stimulusGO:00713631970.014
circulatory system developmentGO:00723592620.014
inorganic cation transmembrane transportGO:00986621940.014
mitochondrion organizationGO:00070051560.014
dna repairGO:00062811980.014
regulation of establishment of protein localizationGO:00702012420.014
regulation of ras protein signal transductionGO:00465781550.014
visual behaviorGO:000763220.014
circadian behaviorGO:004851220.014
regulation of intracellular transportGO:00323861950.014
protein autophosphorylationGO:00467771230.013
regulation of body fluid levelsGO:0050878990.013
neurogenesisGO:00220081690.013
Fly
reactive nitrogen species metabolic processGO:200105730.013
rna processingGO:00063962550.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
positive regulation of gtp catabolic processGO:00331261660.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
protein modification by small protein conjugationGO:00324463420.013
rhythmic behaviorGO:000762220.013
cell substrate adhesionGO:00315891320.013
negative regulation of intracellular signal transductionGO:19025321830.013
glycoprotein biosynthetic processGO:0009101910.013
rho protein signal transductionGO:0007266260.013
glycerolipid metabolic processGO:00464861070.013
positive regulation of ion transportGO:0043270870.013
response to nitrogen compoundGO:19016981840.013
atp catabolic processGO:00062001570.013
regulation of peptidyl tyrosine phosphorylationGO:00507301080.013
actin filament based processGO:00300292240.013
regulation of locomotionGO:00400123290.013
response to other organismGO:00517072610.013
cellular calcium ion homeostasisGO:00068741170.013
regulation of multi organism processGO:00439001570.013
central nervous system developmentGO:00074171230.012
regulation of homeostatic processGO:00328441210.012
hindbrain developmentGO:003090230.012
striated muscle contractionGO:0006941520.012
modification dependent macromolecule catabolic processGO:00436322120.012
growthGO:00400072020.012
carboxylic acid transportGO:0046942630.012
regulation of protein processingGO:00706131500.012
Human
negative regulation of protein processingGO:00109551420.012
Human
response to organonitrogen compoundGO:00102431560.012
regulation of peptidase activityGO:00525471800.012
Human
cell cycle phase transitionGO:00447701730.012
regulation of ion transmembrane transporter activityGO:0032412720.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
protein targetingGO:00066051870.012
positive regulation of programmed cell deathGO:00430682490.012
cell projection assemblyGO:00300311260.012
behavioral response to ethanolGO:004814920.012
anion transmembrane transportGO:0098656760.012
regulation of apoptotic signaling pathwayGO:20012331750.012
positive regulation of cell migrationGO:00303351720.012
positive regulation of apoptotic processGO:00430652460.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
sequestering of calcium ionGO:0051208170.012
tripartite regional subdivisionGO:000735120.012
chromatin organizationGO:00063253510.012
hemopoiesisGO:00300971800.012
neuroblast proliferationGO:000740540.012
cellular response to nitrogen compoundGO:19016991440.012
cellular carbohydrate metabolic processGO:0044262840.012
ubiquitin dependent protein catabolic processGO:00065112060.012
protein ubiquitinationGO:00165673140.012
cellular response to organonitrogen compoundGO:00714171240.012
chemotaxisGO:00069351570.012
positive regulation of cell deathGO:00109422630.012
establishment of protein localization to membraneGO:00901501210.012
immune system developmentGO:00025201950.012
cell projection morphogenesisGO:00488581290.012
compound eye developmentGO:004874910.012
tissue regenerationGO:004224630.012
visual learningGO:000854210.012
cell divisionGO:00513011680.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
negative regulation of proteolysisGO:00458611320.012
Human
regulation of secretionGO:00510461940.012
negative regulation of apoptotic processGO:00430663160.012
tissue morphogenesisGO:0048729960.012
symbiosis encompassing mutualism through parasitismGO:00444031560.011
Human
g protein coupled receptor signaling pathwayGO:00071862070.011
negative regulation of phosphorylationGO:00423261740.011
regulation of cytokine productionGO:00018172320.011
Human
cellular cation homeostasisGO:00300031630.011
regulation of protein maturationGO:19033171500.011
Human
anterior posterior axis specification embryoGO:000859520.011
cell cell signalingGO:00072671550.011
cellular macromolecular complex assemblyGO:00346223240.011
proteasomal protein catabolic processGO:00104981760.011
positive regulation of secretionGO:00510471160.011
regulation of meiotic cell cycleGO:005144540.011
neuron projection developmentGO:00311751060.011
cell growthGO:00160491600.011
generation of neuronsGO:00486991520.011
Fly
modification dependent protein catabolic processGO:00199412090.011
endocytosisGO:00068971590.011
negative regulation of protein modification processGO:00314002000.011
lipid localizationGO:00108761060.011
regulation of response to external stimulusGO:00321012220.011
establishment of protein localization to organelleGO:00725941720.011
cellular response to hormone stimulusGO:00328701250.011
cytosolic calcium ion homeostasisGO:0051480890.011
regulation of ras gtpase activityGO:00323181280.011
response to fungusGO:000962040.011
fatty acid metabolic processGO:00066311150.011
sensory perceptionGO:00076001030.011
regulation of ion transmembrane transportGO:00347651320.011
embryonic epithelial tube formationGO:000183840.011
negative regulation of protein maturationGO:19033181420.011
Human
positive regulation of protein transportGO:00512221350.011
regulation of protein complex assemblyGO:00432541470.011
positive regulation of locomotionGO:00400171860.011
secretion by cellGO:00329402260.011
Human
intrinsic apoptotic signaling pathwayGO:00971931270.011
organelle assemblyGO:00709251760.011
positive regulation of ras gtpase activityGO:00323201170.011
cell part morphogenesisGO:00329901370.011
syncytium formation by plasma membrane fusionGO:000076820.011
plasma membrane organizationGO:00070091150.011
regulation of neural precursor cell proliferationGO:200017740.011
endosomal transportGO:00161971290.011
microtubule cytoskeleton organizationGO:00002261760.011
regulation of immune responseGO:00507762010.011
small molecule catabolic processGO:0044282920.010
lung alveolus developmentGO:004828640.010
regulation of bindingGO:00510981110.010
organic hydroxy compound metabolic processGO:19016151470.010
response to biotic stimulusGO:00096072760.010
organic anion transportGO:00157111030.010
response to drugGO:0042493810.010
positive regulation of steroid hormone biosynthetic processGO:009003120.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
histone modificationGO:00165702510.010
wound healingGO:00420601150.010
regulation of vesicle mediated transportGO:00606271300.010
negative regulation of cell cycleGO:00457861930.010
defense response to fungusGO:005083240.010
regulation of protein catabolic processGO:00421761550.010
Human
regulation of vasculature developmentGO:1901342970.010
posttranscriptional regulation of gene expressionGO:00106082130.010
autophagyGO:0006914880.010
cellular response to cytokine stimulusGO:00713451810.010
negative regulation of blood pressureGO:004577630.010
neurotransmitter secretionGO:000726940.010
positive regulation of map kinase activityGO:0043406800.010
reproductive processGO:00224141060.010
organelle fissionGO:00482851490.010
regulation of dephosphorylationGO:0035303960.010
developmental programmed cell deathGO:001062330.010

PCSK4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.039
cardiovascular system diseaseDOID:12871060.018
central nervous system diseaseDOID:3311860.017
nervous system diseaseDOID:8634310.017
musculoskeletal system diseaseDOID:172230.016
immune system diseaseDOID:29141550.015
inherited metabolic disorderDOID:6552420.014
sensory system diseaseDOID:00501552030.014
disease of cellular proliferationDOID:145661740.012
cancerDOID:1621670.012
organ system cancerDOID:00506861640.012
muscular diseaseDOID:00800001140.012
hematopoietic system diseaseDOID:741000.011
neurodegenerative diseaseDOID:12891020.010