Homo sapiens

88 known processes

CDK5RAP2

CDK5 regulatory subunit associated protein 2

(Aliases: Cep215,C48,MCPH3,DKFZp686B1070,DKFZp686D1070,KIAA1633)

CDK5RAP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule based processGO:00070172100.294
microtubule cytoskeleton organizationGO:00002261760.279
post embryonic developmentGO:000979120.209
cilium assemblyGO:0042384630.138
spindle assemblyGO:0051225290.104
neuromuscular junction developmentGO:000752830.102
intracellular protein transportGO:00068862700.099
organelle assemblyGO:00709251760.092
Mouse
associative learningGO:000830610.090
protein localization to organelleGO:00333652800.089
positive regulation of transportGO:00510503360.083
small gtpase mediated signal transductionGO:0007264780.081
cilium morphogenesisGO:0060271750.081
cilium organizationGO:0044782680.078
positive regulation of hydrolase activityGO:00513453310.078
positive regulation of catabolic processGO:00098963100.069
neurotransmitter secretionGO:000726940.064
single organism cellular localizationGO:19025803320.063
Mouse
mitotic cell cycleGO:00002783260.061
Mouse
regulation of neural precursor cell proliferationGO:200017740.060
rhythmic behaviorGO:000762220.055
regulation of cell cycleGO:00517263930.053
rna interferenceGO:001624640.052
cell part morphogenesisGO:00329901370.051
cellular component morphogenesisGO:00329893140.048
ras protein signal transductionGO:0007265730.047
regulation of proteolysisGO:00301622930.046
protein catabolic processGO:00301633250.045
memoryGO:000761330.045
positive regulation of cellular catabolic processGO:00313312840.044
circadian sleep wake cycle sleepGO:005080220.044
circadian sleep wake cycle processGO:002241020.043
positive regulation of protein transportGO:00512221350.043
cell morphogenesisGO:00009022960.043
locomotory behaviorGO:000762610.043
protein processingGO:00164852260.041
ribonucleoside catabolic processGO:00424544060.041
positive regulation of cellular amine metabolic processGO:003324070.040
regulation of cellular amine metabolic processGO:0033238110.040
metal ion transportGO:00300012720.040
lipid metabolic processGO:00066293810.040
nucleoside phosphate catabolic processGO:19012924120.040
cell projection organizationGO:00300302520.039
glycosyl compound catabolic processGO:19016584130.039
cell projection assemblyGO:00300311260.039
regulation of cell cycle processGO:00105642660.039
positive regulation of intracellular protein transportGO:0090316760.037
regulation of intracellular transportGO:00323861950.037
cellular protein catabolic processGO:00442572610.037
positive regulation of cellular amino acid metabolic processGO:004576430.036
purine nucleotide catabolic processGO:00061954050.036
regulation of cellular component biogenesisGO:00440872810.036
Mouse
chemical homeostasisGO:00488783060.035
regulation of protein localizationGO:00328802960.035
nuclear transportGO:00511691790.035
female gamete generationGO:000729220.035
protein maturationGO:00516042330.034
regulation of protein transportGO:00512232130.034
positive regulation of protein phosphorylationGO:00019343130.034
cellular amino acid metabolic processGO:00065201160.033
cellular macromolecule catabolic processGO:00442653800.033
spindle organizationGO:0007051530.033
vesicle mediated transportGO:00161923710.033
matingGO:000761810.033
proteasomal protein catabolic processGO:00104981760.033
purine nucleoside triphosphate catabolic processGO:00091463920.032
circadian sleep wake cycleGO:004274520.032
negative regulation of catalytic activityGO:00430863350.031
oogenesisGO:004847720.031
blastoderm segmentationGO:000735020.031
nucleoside triphosphate catabolic processGO:00091433940.031
spermatid differentiationGO:004851540.031
amine metabolic processGO:0009308440.030
oocyte differentiationGO:000999420.030
atp metabolic processGO:00460341760.030
circadian behaviorGO:004851220.030
regulation of protein bindingGO:0043393660.030
neurological system processGO:00508771630.030
meiotic chromosome segregationGO:004513240.030
ion homeostasisGO:00508012300.029
cellular component assembly involved in morphogenesisGO:0010927730.029
organophosphate catabolic processGO:00464344300.029
ribonucleotide catabolic processGO:00092614050.029
purine containing compound catabolic processGO:00725234110.029
cellular response to oxygen containing compoundGO:19017012760.029
positive regulation of peptidase activityGO:0010952880.028
nucleotide catabolic processGO:00091664080.028
protein ubiquitinationGO:00165673140.028
regulation of bindingGO:00510981110.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
anatomical structure formation involved in morphogenesisGO:00486462840.028
regulation of cysteine type endopeptidase activityGO:20001161270.028
cellular amine metabolic processGO:0044106410.027
positive regulation of apoptotic processGO:00430652460.027
cation transportGO:00068123310.027
regulation of endopeptidase activityGO:00525481700.027
proteolysis involved in cellular protein catabolic processGO:00516032440.027
cell projection morphogenesisGO:00488581290.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
protein modification by small protein removalGO:0070646920.026
purine ribonucleotide catabolic processGO:00091544040.026
negative regulation of cell cycleGO:00457861930.026
Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.026
negative regulation of phosphate metabolic processGO:00459362670.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
positive regulation of neural precursor cell proliferationGO:200017920.025
purine ribonucleoside metabolic processGO:00461284370.025
positive regulation of endopeptidase activityGO:0010950840.024
establishment of protein localization to organelleGO:00725941720.024
system processGO:00030083490.024
cellular ketone metabolic processGO:0042180800.024
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.024
cell adhesionGO:00071553250.024
negative regulation of cellular protein metabolic processGO:00322693530.024
epithelium developmentGO:00604292270.023
response to other organismGO:00517072610.023
cytoplasmic transportGO:00164823790.023
epithelial cell migrationGO:00106311190.023
cellular chemical homeostasisGO:00550821800.023
protein acylationGO:00435431380.023
positive regulation of proteolysisGO:00458621420.023
positive regulation of transferase activityGO:00513472270.023
positive regulation of phosphorylationGO:00423273940.023
ubiquitin dependent protein catabolic processGO:00065112060.023
single organism membrane organizationGO:00448022680.023
establishment or maintenance of cytoskeleton polarityGO:003095230.023
cellular macromolecular complex assemblyGO:00346223240.022
response to oxygen containing compoundGO:19017003690.022
regulation of nervous system developmentGO:0051960880.022
Mouse
purine nucleoside monophosphate catabolic processGO:00091281580.022
actin mediated cell contractionGO:0070252120.022
cell cycle phase transitionGO:00447701730.022
positive regulation of nucleocytoplasmic transportGO:0046824540.022
immune responseGO:00069553070.022
neuroblast proliferationGO:000740540.021
negative regulation of phosphorus metabolic processGO:00105632670.021
morphogenesis of embryonic epitheliumGO:001633140.021
nervous system developmentGO:00073992930.021
Mouse
positive regulation of cytoplasmic transportGO:1903651820.021
secretionGO:00469032540.021
negative regulation of protein metabolic processGO:00512483910.021
biological adhesionGO:00226103310.021
somitogenesisGO:000175620.021
symbiosis encompassing mutualism through parasitismGO:00444031560.021
neural tube formationGO:000184130.021
rho protein signal transductionGO:0007266260.020
chromatin modificationGO:00165682980.020
regulation of response to external stimulusGO:00321012220.020
epithelium migrationGO:00901321190.020
regulation of cytoplasmic transportGO:19036491490.020
negative regulation of multicellular organismal processGO:00512413170.020
Mouse
oocyte developmentGO:004859910.020
purine nucleoside catabolic processGO:00061523980.020
nucleoside catabolic processGO:00091644080.020
regulation of mitotic cell cycleGO:00073461890.020
protein modification by small protein conjugationGO:00324463420.020
ribonucleoside monophosphate catabolic processGO:00091581580.019
regulation of cellular amino acid metabolic processGO:000652160.019
negative regulation of developmental processGO:00510932470.019
Mouse
cellular response to external stimulusGO:00714961110.019
positive regulation of intracellular transportGO:00323881040.019
positive regulation of cell deathGO:00109422630.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.019
regulation of meiotic cell cycleGO:005144540.019
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.019
alcohol metabolic processGO:00060661140.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
positive regulation of cell proliferationGO:00082843010.019
positive regulation of cellular component organizationGO:00511303760.019
chromosome segregationGO:00070591140.019
embryonic epithelial tube formationGO:000183840.019
innate immune responseGO:00450871780.019
endothelial cell migrationGO:0043542860.019
protein targeting to nucleusGO:00447441040.018
defense responseGO:00069523150.018
hemopoiesisGO:00300971800.018
chromatin organizationGO:00063253510.018
regulation of cell motilityGO:20001452990.018
peptidyl lysine acetylationGO:00183941010.018
reactive oxygen species metabolic processGO:0072593750.018
positive regulation of cysteine type endopeptidase activityGO:2001056790.018
regulation of behaviorGO:0050795820.018
blastocyst developmentGO:000182430.018
regulation of purine nucleotide metabolic processGO:19005422640.018
cell divisionGO:00513011680.018
regulation of nucleotide catabolic processGO:00308112050.018
positive regulation of nucleotide metabolic processGO:00459812300.018
response to hormoneGO:00097251750.018
anterior posterior axis specificationGO:000994820.017
behaviorGO:00076101120.017
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.017
purine ribonucleoside catabolic processGO:00461303980.017
cation transmembrane transportGO:00986552380.017
regulation of purine nucleotide catabolic processGO:00331212050.017
blood vessel morphogenesisGO:00485141620.017
cell substrate adhesionGO:00315891320.017
zymogen activationGO:0031638700.017
response to abiotic stimulusGO:00096283360.017
chromatin assemblyGO:0031497610.017
nucleoside monophosphate metabolic processGO:00091231910.017
negative regulation of protein modification processGO:00314002000.017
dephosphorylationGO:00163112090.017
autophagyGO:0006914880.017
nucleoside monophosphate catabolic processGO:00091251590.017
engulfment of apoptotic cellGO:004365220.017
cellular response to hormone stimulusGO:00328701250.017
regulation of intracellular protein transportGO:00331571230.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
endosomal transportGO:00161971290.017
regulation of synaptic plasticityGO:004816730.017
regulation of nucleoside metabolic processGO:00091182090.017
regulation of cellular ketone metabolic processGO:0010565500.017
hindbrain developmentGO:003090230.016
activation of cysteine type endopeptidase activityGO:0097202570.016
nuclear divisionGO:00002801280.016
regulation of establishment of protein localizationGO:00702012420.016
response to organonitrogen compoundGO:00102431560.016
atp catabolic processGO:00062001570.016
positive regulation of programmed cell deathGO:00430682490.016
actin filament based movementGO:0030048170.016
head developmentGO:00603221080.016
Mouse
cellular homeostasisGO:00197251960.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
response to lipidGO:00339932060.016
cytokine productionGO:00018162470.016
cellular response to endogenous stimulusGO:00714953360.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
macromolecule methylationGO:0043414970.016
neural tube closureGO:000184330.016
regulation of multi organism processGO:00439001570.016
cellular lipid metabolic processGO:00442553030.016
regulation of peptidase activityGO:00525471800.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
transmembrane transportGO:00550853990.016
ossificationGO:00015031210.016
protein targetingGO:00066051870.016
regulation of locomotionGO:00400123290.016
adult locomotory behaviorGO:000834410.015
regulation of cytokine productionGO:00018172320.015
negative regulation of cell proliferationGO:00082852280.015
vasculature developmentGO:00019441810.015
oxidation reduction processGO:00551143960.015
regulation of nucleocytoplasmic transportGO:0046822980.015
somatic stem cell maintenanceGO:003501940.015
compound eye developmentGO:004874910.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
cellular response to nitrogen compoundGO:19016991440.015
endocytosisGO:00068971590.015
cardiovascular system developmentGO:00723582620.015
regulation of neuroblast proliferationGO:190269230.015
anterior posterior axis specification embryoGO:000859520.015
cellular metal ion homeostasisGO:00068751460.015
response to inorganic substanceGO:00100351270.015
regulation of cell migrationGO:00303342890.015
negative regulation of cellular component organizationGO:00511292350.015
Mouse
cardiac muscle cell contractionGO:008600340.014
tripartite regional subdivisionGO:000735120.014
determination of adult lifespanGO:000834020.014
spinal cord developmentGO:002151040.014
positive regulation of cell cycle processGO:00900681060.014
positive regulation of nucleoside metabolic processGO:00459791860.014
tissue migrationGO:00901301190.014
regulation of anatomical structure morphogenesisGO:00226032860.014
protein importGO:00170381300.014
motor neuron axon guidanceGO:000804520.014
regulation of nucleotide metabolic processGO:00061402690.014
endomembrane system organizationGO:00102561960.014
nucleocytoplasmic transportGO:00069131760.014
protein acetylationGO:00064731160.014
membrane organizationGO:00610242920.014
secretion by cellGO:00329402260.014
sensory perceptionGO:00076001030.014
positive regulation of cell cycleGO:00457871400.014
tube closureGO:006060630.014
neuron differentiationGO:00301821380.014
Mouse
negative regulation of cell migrationGO:00303361020.014
limbic system developmentGO:002176130.013
regulation of cellular response to stressGO:00801352440.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
single organism nuclear importGO:19025931040.013
regulation of system processGO:00440571010.013
negative regulation of hydrolase activityGO:00513461820.013
small molecule biosynthetic processGO:00442831570.013
response to extracellular stimulusGO:0009991850.013
sequestering of metal ionGO:0051238240.013
cellular response to growth factor stimulusGO:00713631970.013
modification dependent protein catabolic processGO:00199412090.013
pattern specification processGO:0007389430.013
monovalent inorganic cation transportGO:00156721280.013
regulation of cell differentiationGO:00455953930.013
Mouse
nucleoside triphosphate metabolic processGO:00091414220.013
regulation of protein catabolic processGO:00421761550.013
regulation of ras protein signal transductionGO:00465781550.013
cellular response to starvationGO:0009267580.013
regulation of circadian sleep wake cycleGO:004274920.013
glial cell migrationGO:000834740.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
dna packagingGO:0006323770.013
ameboidal type cell migrationGO:00016671350.013
sodium ion transportGO:0006814610.013
regulation of kinase activityGO:00435493140.013
response to bacteriumGO:00096171440.013
regulation of transferase activityGO:00513383550.013
sequestering of calcium ionGO:0051208170.013
i kappab kinase nf kappab signalingGO:00072491660.013
regulation of cellular protein catabolic processGO:1903362960.013
chemotaxisGO:00069351570.012
cellular cation homeostasisGO:00300031630.012
positive regulation of smoothened signaling pathwayGO:004588040.012
central nervous system developmentGO:00074171230.012
Mouse
posttranscriptional gene silencing by rnaGO:0035194250.012
gene silencingGO:0016458490.012
negative regulation of protein bindingGO:0032091350.012
segmentationGO:003528240.012
inorganic ion transmembrane transportGO:00986602310.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
multi organism cellular processGO:00447641560.012
metal ion homeostasisGO:00550651690.012
nuclear exportGO:0051168690.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
negative regulation of smoothened signaling pathwayGO:004587930.012
response to nitrogen compoundGO:19016981840.012
positive regulation of cellular component biogenesisGO:00440891580.012
negative regulation of bindingGO:0051100570.012
response to radiationGO:00093141510.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
tube developmentGO:00352951250.012
regulation of cytoskeleton organizationGO:00514931770.012
Mouse
response to external biotic stimulusGO:00432072610.012
protein localization to membraneGO:00726571600.012
lipid modificationGO:0030258840.012
regulation of protein kinase activityGO:00458592890.012
primary neural tube formationGO:001402030.012
interspecies interaction between organismsGO:00444191560.012
angiogenesisGO:00015251470.012
photoreceptor cell differentiationGO:004653020.012
cellular response to dna damage stimulusGO:00069743790.012
regulation of cellular component sizeGO:0032535820.012
regulation of epithelial cell migrationGO:0010632930.011
organelle fissionGO:00482851490.011
organic acid biosynthetic processGO:0016053970.011
carboxylic acid biosynthetic processGO:0046394970.011
rna splicingGO:00083801310.011
nuclear importGO:00511701060.011
calcium ion transportGO:00068161470.011
neuron developmentGO:00486661130.011
negative regulation of organelle organizationGO:00106391260.011
Mouse
organ formationGO:004864530.011
negative regulation of embryonic developmentGO:004599240.011
negative regulation of phosphorylationGO:00423261740.011
epithelial cell differentiationGO:00308551410.011
negative regulation of transferase activityGO:00513481240.011
peripheral nervous system developmentGO:000742220.011
negative regulation of protein phosphorylationGO:00019331400.011
oocyte maturationGO:000155610.011
regulation of protein maturationGO:19033171500.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of atp metabolic processGO:1903578290.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
inorganic cation transmembrane transportGO:00986621940.011
signal transduction by phosphorylationGO:00230142970.011
spermatid developmentGO:000728640.011
blood vessel developmentGO:00015681720.011
protein localization to nucleusGO:00345041360.011
mitochondrion organizationGO:00070051560.011
regulation of cell cycle phase transitionGO:19019871260.011
regulation of myeloid leukocyte mediated immunityGO:000288640.011
response to biotic stimulusGO:00096072760.011
cellular response to organonitrogen compoundGO:00714171240.011
brain developmentGO:0007420970.011
Mouse
cranial nerve developmentGO:002154540.011
cellular response to nutrient levelsGO:0031669690.011
cellular response to extracellular stimulusGO:0031668720.011
embryo developmentGO:00097901230.011
response to ionizing radiationGO:0010212650.011
positive regulation of ras gtpase activityGO:00323201170.011
regulation of ion transportGO:00432691890.011
cdc42 protein signal transductionGO:003248840.011
positive regulation of immune system processGO:00026842830.011
cellular calcium ion homeostasisGO:00068741170.011
response to epidermal growth factorGO:0070849140.011
ectodermal placode developmentGO:007169610.011
vacuole organizationGO:0007033440.011
viral life cycleGO:00190581320.011
viral processGO:00160321460.011
response to growth factorGO:00708482050.011
regulation of cell divisionGO:00513021160.011
mapk cascadeGO:00001652880.011
negative regulation of protein kinase activityGO:0006469980.011
cell fate determinationGO:000170930.011
microtubule based movementGO:0007018320.011
regulation of defense responseGO:00313471540.011
circulatory system developmentGO:00723592620.011
negative regulation of growthGO:0045926970.011
regulation of protein processingGO:00706131500.011
negative regulation of locomotionGO:00400131180.011
immune effector processGO:00022521590.010
regulation of mapk cascadeGO:00434082620.010
posttranscriptional regulation of gene expressionGO:00106082130.010
apoptotic signaling pathwayGO:00971902680.010
regulation of neuron differentiationGO:0045664700.010
Mouse
organic hydroxy compound metabolic processGO:19016151470.010
cation homeostasisGO:00550801890.010
peptidyl lysine modificationGO:00182051440.010
learningGO:0007612110.010
regulation of growthGO:00400081650.010
histone modificationGO:00165702510.010
posttranscriptional gene silencingGO:0016441250.010
hippocampus developmentGO:002176610.010
cellular response to peptideGO:1901653590.010
cyclic nucleotide metabolic processGO:0009187820.010
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.010
positive regulation of response to external stimulusGO:0032103880.010
growthGO:00400072020.010
regulation of atpase activityGO:0043462250.010
cell developmentGO:00484683280.010
Mouse
protein dephosphorylationGO:0006470810.010

CDK5RAP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.030
nervous system diseaseDOID:8634310.030
musculoskeletal system diseaseDOID:172230.022
joubert syndromeDOID:0050777180.021
heart diseaseDOID:114680.020
cardiovascular system diseaseDOID:12871060.020
muscle tissue diseaseDOID:661130.014
myopathyDOID:4231040.014
muscular diseaseDOID:00800001140.014
organ system cancerDOID:00506861640.014
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
neurodegenerative diseaseDOID:12891020.013
disease of metabolismDOID:00146672950.013
sensory system diseaseDOID:00501552030.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.011
neuropathyDOID:870520.011
connective tissue diseaseDOID:651090.011
inherited metabolic disorderDOID:6552420.010
bone diseaseDOID:0080001880.010
physical disorderDOID:0080015410.006
congenital nervous system abnormalityDOID:2490210.003
microcephalyDOID:1090760.001