Homo sapiens

38 known processes

XPO1

exportin 1 (CRM1 homolog, yeast)

(Aliases: DKFZp686B1823,CRM1,emb)

XPO1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule cytoskeleton organizationGO:00002261760.869
Mouse Fly
post embryonic developmentGO:000979120.770
Worm
nucleocytoplasmic transportGO:00069131760.540
embryo developmentGO:00097901230.516
Worm
response to oxygen containing compoundGO:19017003690.506
mitotic cell cycleGO:00002783260.495
nuclear exportGO:0051168690.478
female gamete generationGO:000729220.475
microtubule based processGO:00070172100.462
Mouse Fly
regulation of cell cycleGO:00517263930.457
Mouse
chromatin modificationGO:00165682980.413
cytoplasmic transportGO:00164823790.402
cellular response to oxygen containing compoundGO:19017012760.376
response to nitrogen compoundGO:19016981840.376
single organism cellular localizationGO:19025803320.336
positive regulation of cellular component organizationGO:00511303760.319
cellular response to nitrogen compoundGO:19016991440.313
establishment of protein localization to organelleGO:00725941720.304
regulation of microtubule cytoskeleton organizationGO:0070507610.293
Mouse
protein import into nucleusGO:00066061040.285
nuclear transportGO:00511691790.280
mitotic spindle organizationGO:0007052270.279
protein targeting to nucleusGO:00447441040.266
rna transportGO:0050658390.264
Yeast
regulation of cytoskeleton organizationGO:00514931770.261
Mouse
response to hormoneGO:00097251750.247
posttranscriptional regulation of gene expressionGO:00106082130.242
regulation of mitotic cell cycleGO:00073461890.236
protein localization to organelleGO:00333652800.229
Yeast Mouse
regulation of microtubule polymerization or depolymerizationGO:0031110270.218
cellular macromolecular complex assemblyGO:00346223240.214
protein export from nucleusGO:0006611290.213
centrosome organizationGO:0051297580.209
Mouse Fly
cellular response to dna damage stimulusGO:00069743790.206
regulation of microtubule based processGO:0032886740.197
Mouse
single organism nuclear importGO:19025931040.192
ribonucleoside monophosphate metabolic processGO:00091611870.189
mitotic nuclear divisionGO:00070671190.189
cellular response to endogenous stimulusGO:00714953360.182
protein targetingGO:00066051870.181
organelle fissionGO:00482851490.180
nuclear importGO:00511701060.179
protein complex disassemblyGO:0043241520.179
positive regulation of cellular amine metabolic processGO:003324070.177
response to biotic stimulusGO:00096072760.174
intracellular protein transportGO:00068862700.168
protein localization to nucleusGO:00345041360.166
Mouse
rna processingGO:00063962550.166
amine metabolic processGO:0009308440.164
mitotic cell cycle processGO:19030472860.163
nuclear divisionGO:00002801280.163
vesicle mediated transportGO:00161923710.161
positive regulation of organelle organizationGO:00106381950.157
negative regulation of cellular protein metabolic processGO:00322693530.150
positive regulation of transportGO:00510503360.148
response to abiotic stimulusGO:00096283360.147
Fly
oogenesisGO:004847720.139
negative regulation of cellular component organizationGO:00511292350.139
regulation of cell cycle processGO:00105642660.138
Mouse
spindle organizationGO:0007051530.138
nervous system developmentGO:00073992930.136
negative regulation of cell deathGO:00605483450.134
mitotic dna replication checkpointGO:003331420.132
rna interferenceGO:001624640.130
cellular component morphogenesisGO:00329893140.126
response to organic cyclic compoundGO:00140702040.126
regulation of cellular amine metabolic processGO:0033238110.125
regulation of peptidase activityGO:00525471800.124
nls bearing protein import into nucleusGO:000660720.124
determination of adult lifespanGO:000834020.120
protein importGO:00170381300.118
negative regulation of organelle organizationGO:00106391260.115
establishment of rna localizationGO:0051236390.114
Yeast
negative regulation of protein metabolic processGO:00512483910.114
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.113
negative regulation of phosphate metabolic processGO:00459362670.112
nucleobase containing compound transportGO:0015931510.112
Yeast
response to other organismGO:00517072610.112
negative regulation of apoptotic processGO:00430663160.110
atp catabolic processGO:00062001570.110
cellular amine metabolic processGO:0044106410.108
positive regulation of nucleocytoplasmic transportGO:0046824540.107
spermatid developmentGO:000728640.105
cellular protein complex assemblyGO:00436231880.105
purine nucleoside monophosphate catabolic processGO:00091281580.104
cellular amino acid metabolic processGO:00065201160.103
regulation of proteolysisGO:00301622930.100
cell cycle checkpointGO:00000751170.100
rna splicing via transesterification reactionsGO:0000375900.098
negative regulation of phosphorus metabolic processGO:00105632670.096
nitrogen compound transportGO:00717051910.096
Yeast
regulation of nuclear divisionGO:0051783650.095
mrna splicing via spliceosomeGO:0000398890.094
covalent chromatin modificationGO:00165692540.094
chromatin organizationGO:00063253510.093
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.091
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.091
posttranscriptional gene silencingGO:0016441250.086
regulation of cytoplasmic transportGO:19036491490.084
Mouse
microtubule polymerization or depolymerizationGO:0031109370.083
nucleus organizationGO:0006997280.082
regulation of protein targetingGO:1903533910.082
negative regulation of kinase activityGO:00336731060.082
macromolecule methylationGO:0043414970.080
gene silencingGO:0016458490.080
regulation of mitosisGO:0007088630.079
macromolecular complex disassemblyGO:0032984600.078
negative regulation of cell cycle phase transitionGO:1901988890.077
negative regulation of cell differentiationGO:00455961710.077
regulation of endopeptidase activityGO:00525481700.075
regulation of gene expression epigeneticGO:0040029730.073
negative regulation of catalytic activityGO:00430863350.072
regulation of cell differentiationGO:00455953930.072
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.071
Rat
spermatid differentiationGO:004851540.071
regulation of protein localization to nucleusGO:1900180850.071
regulation of cellular amino acid metabolic processGO:000652160.069
cell morphogenesisGO:00009022960.069
chemotaxisGO:00069351570.067
protein depolymerizationGO:0051261300.066
regulation of cell divisionGO:00513021160.064
dna repairGO:00062811980.063
receptor mediated endocytosisGO:0006898840.063
cellular component disassemblyGO:0022411920.063
regulation of viral genome replicationGO:0045069480.062
cellular ketone metabolic processGO:0042180800.062
negative regulation of programmed cell deathGO:00430693210.061
negative regulation of transportGO:00510511760.059
regulation of protein import into nucleusGO:0042306780.059
positive regulation of hydrolase activityGO:00513453310.059
regulation of protein localizationGO:00328802960.059
Mouse
neurogenesisGO:00220081690.059
activation of cysteine type endopeptidase activityGO:0097202570.058
cellular response to hormone stimulusGO:00328701250.058
protein maturationGO:00516042330.058
negative regulation of mitotic cell cycle phase transitionGO:1901991850.058
positive regulation of protein transportGO:00512221350.057
chromatin remodelingGO:0006338550.056
response to lipidGO:00339932060.055
response to organonitrogen compoundGO:00102431560.055
negative regulation of phosphorylationGO:00423261740.055
cell cycle phase transitionGO:00447701730.054
dna recombinationGO:0006310770.054
centrosome duplicationGO:0051298280.054
Mouse Fly
negative regulation of cell cycleGO:00457861930.053
rna splicingGO:00083801310.051
regulation of protein kinase activityGO:00458592890.050
negative regulation of developmental processGO:00510932470.050
regulation of protein complex assemblyGO:00432541470.050
cell type specific apoptotic processGO:00972851250.049
dna conformation changeGO:00711031130.049
cellular response to organic cyclic compoundGO:00714071270.049
cellular carbohydrate metabolic processGO:0044262840.048
centrosome cycleGO:0007098320.048
Mouse Fly
ossificationGO:00015031210.047
spindle elongationGO:005123140.047
oocyte differentiationGO:000999420.046
positive regulation of cellular amino acid metabolic processGO:004576430.045
negative regulation of cell cycle processGO:00109481210.045
peptidyl serine phosphorylationGO:00181051010.044
response to cytokineGO:00340972320.044
oocyte developmentGO:004859910.044
negative regulation of protein complex disassemblyGO:0043242200.044
mitotic spindle elongationGO:000002240.043
response to radiationGO:00093141510.043
regulation of translationGO:0006417890.043
nucleic acid transportGO:0050657390.043
Yeast
mrna metabolic processGO:00160711750.042
cellular response to cytokine stimulusGO:00713451810.042
regulation of dna metabolic processGO:00510521530.042
purine ribonucleoside monophosphate metabolic processGO:00091671860.042
organelle assemblyGO:00709251760.042
Fly
negative regulation of cytoskeleton organizationGO:0051494450.041
positive regulation of protein complex assemblyGO:0031334860.041
histone modificationGO:00165702510.041
enzyme linked receptor protein signaling pathwayGO:00071673030.041
multicellular organismal agingGO:001025930.041
regulation of mitotic cell cycle phase transitionGO:19019901180.041
regulation of cellular component biogenesisGO:00440872810.040
regulation of growthGO:00400081650.040
meiosis iGO:000712740.040
peptidyl serine modificationGO:00182091060.039
mitotic cell cycle checkpointGO:0007093680.039
regulation of establishment of protein localizationGO:00702012420.039
Mouse
gene silencing by rnaGO:0031047260.039
positive regulation of intracellular transportGO:00323881040.039
posttranscriptional gene silencing by rnaGO:0035194250.039
regulation of response to dna damage stimulusGO:2001020940.039
microtubule depolymerizationGO:0007019180.038
intracellular receptor signaling pathwayGO:00305221040.038
regulation of cell growthGO:00015581350.037
response to lipopolysaccharideGO:0032496700.036
positive regulation of phosphorylationGO:00423273940.036
negative regulation of protein phosphorylationGO:00019331400.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
response to external biotic stimulusGO:00432072610.036
maintenance of locationGO:00512351120.035
regulation of intracellular protein transportGO:00331571230.035
Mouse
rna localizationGO:0006403410.035
Yeast
embryo development ending in birth or egg hatchingGO:0009792340.035
Worm
cellular lipid metabolic processGO:00442553030.034
microtubule organizing center organizationGO:0031023620.034
Mouse Fly
protein methylationGO:0006479740.034
immune responseGO:00069553070.033
cell divisionGO:00513011680.033
Worm
regulation of cellular ketone metabolic processGO:0010565500.033
positive regulation of cellular component biogenesisGO:00440891580.033
positive regulation of intracellular protein transportGO:0090316760.033
defense responseGO:00069523150.032
regulation of viral processGO:00507921030.032
symbiosis encompassing mutualism through parasitismGO:00444031560.032
positive regulation of immune system processGO:00026842830.032
metaphase plate congressionGO:0051310180.032
cellular protein complex disassemblyGO:0043624360.032
multicellular organismal reproductive processGO:0048609400.031
regulation of multi organism processGO:00439001570.031
regulation of intracellular transportGO:00323861950.031
Mouse
cell activationGO:00017752130.031
regulation of centrosome cycleGO:0046605150.030
Mouse
cell part morphogenesisGO:00329901370.030
regulation of meiosisGO:004002030.030
secretionGO:00469032540.030
cell projection organizationGO:00300302520.029
nucleoside phosphate catabolic processGO:19012924120.029
lipid metabolic processGO:00066293810.029
regulation of cell cycle phase transitionGO:19019871260.029
histone phosphorylationGO:0016572160.029
actin filament based processGO:00300292240.029
regulation of cysteine type endopeptidase activityGO:20001161270.029
negative regulation of transferase activityGO:00513481240.029
regulation of cytokine productionGO:00018172320.029
purine ribonucleoside metabolic processGO:00461284370.029
negative regulation of protein modification processGO:00314002000.028
reproductive structure developmentGO:0048608550.028
organelle localizationGO:0051640840.028
cell cycle g2 m phase transitionGO:0044839430.028
regulation of rna splicingGO:0043484620.028
positive regulation of cell developmentGO:0010720920.028
sex differentiationGO:0007548450.027
reproductionGO:0000003630.027
Worm
regulation of kinase activityGO:00435493140.027
response to steroid hormoneGO:0048545800.027
interspecies interaction between organismsGO:00444191560.027
nucleoside monophosphate metabolic processGO:00091231910.027
lymphocyte activationGO:00466491330.027
positive regulation of protein import into nucleusGO:0042307460.026
g2 m transition of mitotic cell cycleGO:0000086410.026
regulation of histone h3 k27 methylationGO:006108540.026
spindle assemblyGO:0051225290.026
nucleotide catabolic processGO:00091664080.026
chemical homeostasisGO:00488783060.026
regulation of protein depolymerizationGO:1901879220.026
growthGO:00400072020.026
atp metabolic processGO:00460341760.026
negative regulation of chromosome organizationGO:2001251480.025
regulation of mrna processingGO:0050684480.025
system processGO:00030083490.025
regenerationGO:003109940.025
protein dna complex assemblyGO:0065004640.025
mrna processingGO:00063971330.025
response to alcoholGO:0097305640.025
protein processingGO:00164852260.025
nucleoside triphosphate catabolic processGO:00091433940.025
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.024
cell developmentGO:00484683280.024
taxisGO:00423301570.024
cellular response to peptideGO:1901653590.024
neuron differentiationGO:00301821380.024
regulation of meiotic cell cycleGO:005144540.024
regulation of mrna splicing via spliceosomeGO:0048024320.024
regulation of nucleocytoplasmic transportGO:0046822980.023
Mouse
neuron projection developmentGO:00311751060.023
reproductive system developmentGO:0061458560.023
mononuclear cell proliferationGO:0032943710.023
ribonucleoside catabolic processGO:00424544060.023
response to growth factorGO:00708482050.023
signal transduction by phosphorylationGO:00230142970.022
response to inorganic substanceGO:00100351270.022
development of primary sexual characteristicsGO:0045137350.022
single organism reproductive processGO:0044702980.022
developmental process involved in reproductionGO:0003006660.022
positive regulation of proteolysisGO:00458621420.022
cellular response to peptide hormone stimulusGO:0071375560.022
reproductive processGO:00224141060.022
negative regulation of protein depolymerizationGO:1901880170.022
positive regulation of cellular catabolic processGO:00313312840.022
cell morphogenesis involved in differentiationGO:00009041440.022
regulation of locomotionGO:00400123290.022
ameboidal type cell migrationGO:00016671350.022
negative regulation of cytoplasmic transportGO:1903650460.022
positive regulation of cysteine type endopeptidase activityGO:2001056790.022
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.022
regulation of neuron deathGO:1901214560.021
regulation of protein catabolic processGO:00421761550.021
Mouse
neurological system processGO:00508771630.020
methylationGO:00322591060.020
establishment or maintenance of cytoskeleton polarityGO:003095230.020
neuron apoptotic processGO:0051402390.020
neuron developmentGO:00486661130.020
dsrna fragmentationGO:0031050130.020
cellular response to insulin stimulusGO:0032869410.020
gonad developmentGO:0008406340.020
purine nucleoside triphosphate metabolic processGO:00091444120.019
generation of neuronsGO:00486991520.019
positive regulation of cytoplasmic transportGO:1903651820.019
response to alkaloidGO:0043279200.019
negative regulation of neuron deathGO:1901215320.019
cell projection morphogenesisGO:00488581290.019
cellular response to abiotic stimulusGO:00712141170.018
establishment or maintenance of cell polarityGO:0007163310.018
mitotic cell cycle phase transitionGO:00447721620.018
ribonucleoside monophosphate catabolic processGO:00091581580.018
peptidyl threonine modificationGO:0018210450.018
dna packagingGO:0006323770.018
response to insulinGO:0032868450.018
negative regulation of neuron apoptotic processGO:0043524230.018
mitotic centrosome separationGO:000710010.017
nucleoside monophosphate catabolic processGO:00091251590.017
generation of precursor metabolites and energyGO:0006091680.017
regulation of cellular response to stressGO:00801352440.017
Fly
regulation of protein processingGO:00706131500.017
small gtpase mediated signal transductionGO:0007264780.016
negative regulation of mitotic cell cycleGO:00459301020.016
positive regulation of cell cycle processGO:00900681060.016
male gamete generationGO:0048232220.016
agingGO:0007568660.016
endocytosisGO:00068971590.016
stem cell differentiationGO:0048863930.015
dna integrity checkpointGO:0031570710.015
microtubule polymerizationGO:0046785180.015
central nervous system developmentGO:00074171230.015
zymogen activationGO:0031638700.015
immune effector processGO:00022521590.015
regulation of cell shapeGO:0008360480.015
organophosphate catabolic processGO:00464344300.015
cellular homeostasisGO:00197251960.015
neuron deathGO:0070997650.015
cell adhesionGO:00071553250.015
rna catabolic processGO:0006401710.015
positive regulation of cell cycleGO:00457871400.015
muscle cell differentiationGO:0042692630.015
protein polymerizationGO:0051258710.015
leukocyte proliferationGO:0070661740.015
regulation of cell developmentGO:00602841610.015
neuron projection morphogenesisGO:0048812500.015
response to bacteriumGO:00096171440.014
actin cytoskeleton organizationGO:00300362070.014
negative regulation of microtubule depolymerizationGO:0007026120.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
cellular response to lipidGO:00713961270.014
mapk cascadeGO:00001652880.014
sensory perceptionGO:00076001030.014
meiotic nuclear divisionGO:0007126100.014
regulation of cell migrationGO:00303342890.014
neuroblast proliferationGO:000740540.014
behaviorGO:00076101120.014
cell junction organizationGO:0034330790.014
multi organism reproductive processGO:0044703540.014
multicellular organism reproductionGO:0032504420.014
regulation of protein transportGO:00512232130.013
Mouse
spindle assembly involved in mitosisGO:0090307120.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
response to molecule of bacterial originGO:0002237820.013
regulation of mrna metabolic processGO:1903311530.013
mitotic dna integrity checkpointGO:0044774300.013
regulation of body fluid levelsGO:0050878990.013
regulation of anatomical structure morphogenesisGO:00226032860.013
ribonucleoprotein complex biogenesisGO:00226131160.013
mitotic dna damage checkpointGO:0044773280.013
negative regulation of dna metabolic processGO:0051053570.012
regulation of neuron apoptotic processGO:0043523350.012
cell morphogenesis involved in neuron differentiationGO:0048667440.012
regulation of homeostatic processGO:00328441210.012
alternative mrna splicing via spliceosomeGO:0000380270.012
sexual reproductionGO:0019953370.012
brain developmentGO:0007420970.012
stem cell developmentGO:0048864690.012
i kappab kinase nf kappab signalingGO:00072491660.012
maintenance of protein location in cellGO:0032507560.012
positive regulation of cell differentiationGO:00455972110.012
ribosome assemblyGO:004225590.012
negative regulation of protein kinase activityGO:0006469980.012
cognitionGO:0050890430.012
ribonucleoprotein complex subunit organizationGO:0071826810.012
viral life cycleGO:00190581320.012
leukocyte activationGO:00453211640.012
response to peptide hormoneGO:0043434610.012
regulation of protein bindingGO:0043393660.012
positive regulation of protein phosphorylationGO:00019343130.012
positive regulation of mitotic cell cycleGO:0045931600.011
segmentationGO:003528240.011
cellular response to oxidative stressGO:0034599850.011
response to virusGO:00096151260.011
negative regulation of growthGO:0045926970.011
developmental growth involved in morphogenesisGO:0060560230.011
associative learningGO:000830610.011
negative regulation of protein serine threonine kinase activityGO:0071901570.011
ribonucleotide catabolic processGO:00092614050.011
positive regulation of kinase activityGO:00336742040.011
positive regulation of cell proliferationGO:00082843010.011
cellular macromolecule catabolic processGO:00442653800.011
ribosomal small subunit export from nucleusGO:000005630.011
apoptotic signaling pathwayGO:00971902680.011
response to temperature stimulusGO:0009266220.011
carbohydrate metabolic processGO:00059752070.011
lipid localizationGO:00108761060.011
positive regulation of transferase activityGO:00513472270.011
membrane organizationGO:00610242920.011
negative regulation of intracellular transportGO:0032387600.011
dna replicationGO:00062601160.011
protein alkylationGO:0008213740.011
single organism carbohydrate metabolic processGO:00447231930.011
myeloid cell differentiationGO:00300991170.010
axon developmentGO:0061564340.010
skin developmentGO:0043588760.010
establishment of cell polarityGO:0030010220.010
regulation of response to cytokine stimulusGO:0060759460.010
actin filament based movementGO:0030048170.010
cell growthGO:00160491600.010
peptidyl tyrosine phosphorylationGO:00181081700.010
positive regulation of catabolic processGO:00098963100.010

XPO1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.025
nervous system diseaseDOID:8634310.025