Homo sapiens

0 known processes

TTK

TTK protein kinase

(Aliases: MPS1L1,FLJ38280,PYT,MPS1,CT96,ESK)

TTK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule cytoskeleton organizationGO:00002261760.863
Yeast
microtubule based processGO:00070172100.820
Yeast
sister chromatid segregationGO:0000819540.703
Yeast
nuclear divisionGO:00002801280.577
Yeast Zebrafish
organelle fissionGO:00482851490.566
Yeast Zebrafish
chromosome segregationGO:00070591140.533
Yeast Zebrafish
spindle assemblyGO:0051225290.532
Yeast
spindle assembly involved in mitosisGO:0090307120.511
mitotic sister chromatid segregationGO:0000070530.481
Yeast
regulation of microtubule based processGO:0032886740.478
Yeast
mitotic cell cycleGO:00002783260.471
Yeast Zebrafish
organelle assemblyGO:00709251760.469
Yeast
spindle organizationGO:0007051530.405
Yeast
cell divisionGO:00513011680.402
Yeast
attachment of spindle microtubules to kinetochoreGO:0008608170.371
Yeast
regulation of cell cycle processGO:00105642660.320
Yeast Zebrafish
maintenance of location in cellGO:0051651620.312
Yeast
regulation of spindle organizationGO:0090224100.310
maintenance of locationGO:00512351120.305
Yeast
regulation of cell cycleGO:00517263930.299
Yeast Zebrafish
stem cell divisionGO:001714520.294
centrosome organizationGO:0051297580.290
positive regulation of cell cycleGO:00457871400.204
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.204
Yeast
negative regulation of cellular component organizationGO:00511292350.196
Yeast
microtubule anchoringGO:0034453240.187
Yeast
mitotic spindle midzone assemblyGO:005125640.174
regulation of mitosisGO:0007088630.170
Yeast
mitotic nuclear divisionGO:00070671190.166
Yeast
organophosphate catabolic processGO:00464344300.159
microtubule organizing center organizationGO:0031023620.159
Yeast
regulation of mitotic spindle organizationGO:006023660.150
glycosyl compound catabolic processGO:19016584130.148
regulation of cytoskeleton organizationGO:00514931770.132
Yeast
ribonucleoside triphosphate catabolic processGO:00092033910.131
regulation of proteasomal protein catabolic processGO:0061136870.130
Yeast
maintenance of protein location in cellGO:0032507560.120
Yeast
mitotic cell cycle processGO:19030472860.117
Yeast Zebrafish
protein depolymerizationGO:0051261300.115
organelle localizationGO:0051640840.114
Yeast
positive regulation of cell cycle processGO:00900681060.111
ribonucleoside catabolic processGO:00424544060.111
cellular macromolecular complex assemblyGO:00346223240.110
meiosis iGO:000712740.106
regulation of chromosome segregationGO:0051983440.105
Yeast
oogenesisGO:004847720.104
mitotic spindle organizationGO:0007052270.103
microtubule based movementGO:0007018320.103
microtubule polymerization or depolymerizationGO:0031109370.100
nucleoside triphosphate metabolic processGO:00091414220.099
cytoskeleton dependent cytokinesisGO:0061640220.097
purine nucleoside catabolic processGO:00061523980.094
chromatin modificationGO:00165682980.091
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.088
Yeast
histone serine phosphorylationGO:003540440.087
protein processingGO:00164852260.086
Yeast
cellular protein complex assemblyGO:00436231880.082
spindle midzone assemblyGO:005125540.081
positive regulation of organelle organizationGO:00106381950.081
negative regulation of proteolysisGO:00458611320.079
Yeast
centrosome separationGO:005129930.077
blastocyst developmentGO:000182430.077
post embryonic developmentGO:000979120.077
meiotic chromosome segregationGO:004513240.074
Zebrafish
posttranscriptional regulation of gene expressionGO:00106082130.073
nervous system developmentGO:00073992930.071
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.070
Yeast
mitotic spindle elongationGO:000002240.068
spindle elongationGO:005123140.068
negative regulation of protein metabolic processGO:00512483910.068
Yeast
somatic stem cell divisionGO:004810310.068
regulation of cell divisionGO:00513021160.067
Yeast
mitotic centrosome separationGO:000710010.067
neurogenesisGO:00220081690.067
regulation of mitotic cell cycleGO:00073461890.066
Yeast Zebrafish
protein polymerizationGO:0051258710.066
proteasomal protein catabolic processGO:00104981760.066
Yeast
ribonucleotide catabolic processGO:00092614050.066
regulation of protein localizationGO:00328802960.065
Yeast
nucleoside phosphate catabolic processGO:19012924120.063
nucleoside triphosphate catabolic processGO:00091433940.062
ras protein signal transductionGO:0007265730.062
regulation of wnt signaling pathwayGO:00301111230.061
small gtpase mediated signal transductionGO:0007264780.061
single organism cellular localizationGO:19025803320.061
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.060
Yeast
nucleoside monophosphate catabolic processGO:00091251590.059
cellular macromolecule catabolic processGO:00442653800.058
Yeast
purine nucleoside triphosphate metabolic processGO:00091444120.058
neuroblast divisionGO:005505710.058
regulation of bindingGO:00510981110.058
protein autophosphorylationGO:00467771230.058
purine containing compound catabolic processGO:00725234110.057
negative regulation of apoptotic processGO:00430663160.056
regulation of mitotic sister chromatid separationGO:0010965270.056
Yeast
peptidyl serine phosphorylationGO:00181051010.055
purine ribonucleotide catabolic processGO:00091544040.055
establishment of organelle localizationGO:0051656590.053
Yeast
regulation of protein catabolic processGO:00421761550.052
Yeast
positive regulation of catabolic processGO:00098963100.052
proteolysis involved in cellular protein catabolic processGO:00516032440.051
Yeast
negative regulation of organelle organizationGO:00106391260.051
Yeast
regulation of transferase activityGO:00513383550.051
regulation of mitotic sister chromatid segregationGO:0033047270.051
Yeast
protein ubiquitinationGO:00165673140.050
metaphase anaphase transition of mitotic cell cycleGO:0007091210.049
Yeast
positive regulation of protein catabolic processGO:0045732750.048
protein catabolic processGO:00301633250.048
Yeast
cell fate determinationGO:000170930.048
regulation of mitotic metaphase anaphase transitionGO:0030071260.047
Yeast
neuroblast proliferationGO:000740540.047
canonical wnt signaling pathwayGO:00600701160.046
cellular amino acid metabolic processGO:00065201160.046
regulation of microtubule cytoskeleton organizationGO:0070507610.046
Yeast
positive regulation of protein phosphorylationGO:00019343130.045
maintenance of protein locationGO:0045185570.045
Yeast
wnt signaling pathwayGO:00160551560.043
cellular protein catabolic processGO:00442572610.043
Yeast
regulation of proteolysisGO:00301622930.043
Yeast
peptidyl serine modificationGO:00182091060.043
cytokinesisGO:0000910960.043
regenerationGO:003109940.042
Zebrafish
ribonucleoside monophosphate catabolic processGO:00091581580.042
regulation of sister chromatid segregationGO:0033045270.041
Yeast
chromatin organizationGO:00063253510.041
positive regulation of mitosisGO:0045840250.041
positive regulation of cellular component organizationGO:00511303760.040
negative regulation of protein processingGO:00109551420.040
Yeast
ribonucleoside triphosphate metabolic processGO:00091994120.040
regulation of nuclear divisionGO:0051783650.038
Yeast
centrosome cycleGO:0007098320.038
negative regulation of mitotic anaphase promoting complex activityGO:006056440.037
meiotic nuclear divisionGO:0007126100.037
Zebrafish
negative regulation of programmed cell deathGO:00430693210.037
microtubule cytoskeleton organization involved in mitosisGO:1902850150.037
Yeast
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.037
Yeast
positive regulation of phosphorylationGO:00423273940.036
cardiovascular system developmentGO:00723582620.035
regulation of cellular protein catabolic processGO:1903362960.035
Yeast
anatomical structure formation involved in morphogenesisGO:00486462840.035
regulation of cellular amine metabolic processGO:0033238110.035
protein maturationGO:00516042330.034
Yeast
negative regulation of cell cycleGO:00457861930.034
Yeast Zebrafish
purine nucleoside triphosphate catabolic processGO:00091463920.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
modification dependent protein catabolic processGO:00199412090.034
Yeast
mitotic cytokinesisGO:0000281190.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
modification dependent macromolecule catabolic processGO:00436322120.033
Yeast
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.033
protein localization to organelleGO:00333652800.033
mitotic sister chromatid separationGO:0051306180.033
Yeast
negative regulation of mitotic cell cycle phase transitionGO:1901991850.033
Yeast Zebrafish
microtubule polymerizationGO:0046785180.032
cell developmentGO:00484683280.032
cellular component morphogenesisGO:00329893140.032
embryo developmentGO:00097901230.032
Zebrafish
regulation of cell differentiationGO:00455953930.032
regulation of cellular amino acid metabolic processGO:000652160.032
purine ribonucleoside catabolic processGO:00461303980.032
negative regulation of cell divisionGO:0051782310.031
Yeast
response to abiotic stimulusGO:00096283360.031
negative regulation of cell deathGO:00605483450.031
nucleus localizationGO:005164710.031
negative regulation of cell cycle processGO:00109481210.031
Yeast Zebrafish
neuron differentiationGO:00301821380.030
cellular protein complex disassemblyGO:0043624360.030
dna repairGO:00062811980.030
regulation of cytoplasmic transportGO:19036491490.030
positive regulation of cytoskeleton organizationGO:0051495830.030
nucleoside monophosphate metabolic processGO:00091231910.030
positive regulation of apoptotic processGO:00430652460.029
asymmetric neuroblast divisionGO:005505910.029
purine ribonucleoside monophosphate catabolic processGO:00091691580.029
circulatory system developmentGO:00723592620.029
regulation of intracellular protein transportGO:00331571230.029
centrosome duplicationGO:0051298280.029
generation of neuronsGO:00486991520.028
regulation of cell developmentGO:00602841610.028
positive regulation of proteolysisGO:00458621420.027
covalent chromatin modificationGO:00165692540.027
regulation of nervous system developmentGO:0051960880.027
positive regulation of cellular catabolic processGO:00313312840.027
histone modificationGO:00165702510.026
regulation of meiosisGO:004002030.026
determination of adult lifespanGO:000834020.026
female gamete generationGO:000729220.026
cell morphogenesisGO:00009022960.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
negative regulation of protein ubiquitinationGO:0031397350.025
purine nucleoside monophosphate metabolic processGO:00091261860.025
regulation of kinase activityGO:00435493140.025
regulation of small gtpase mediated signal transductionGO:00510561560.024
sister chromatid biorientationGO:003113420.024
Yeast
multicellular organismal agingGO:001025930.024
cellular response to oxygen containing compoundGO:19017012760.024
cilium morphogenesisGO:0060271750.024
protein modification by small protein conjugationGO:00324463420.024
cellular response to dna damage stimulusGO:00069743790.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
regulation of protein processingGO:00706131500.023
Yeast
purine nucleoside monophosphate catabolic processGO:00091281580.023
negative regulation of protein modification processGO:00314002000.022
purine ribonucleoside metabolic processGO:00461284370.022
cellular ketone metabolic processGO:0042180800.022
regulation of protein modification by small protein conjugation or removalGO:19033201070.022
clearance of foreign intracellular dna by conversion of dna cytidine to uridineGO:004435610.022
positive regulation of chromosome organizationGO:2001252410.022
regulation of cellular ketone metabolic processGO:0010565500.022
positive regulation of nuclear divisionGO:0051785270.021
nucleoside catabolic processGO:00091644080.021
negative regulation of cell differentiationGO:00455961710.020
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.020
Yeast
positive regulation of programmed cell deathGO:00430682490.020
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143640.020
negative regulation of ubiquitin protein transferase activityGO:005144480.020
mitotic spindle checkpointGO:0071174180.020
Yeast
mitotic cell cycle phase transitionGO:00447721620.019
Yeast Zebrafish
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.019
positive regulation of mitotic sister chromatid separationGO:190197060.019
establishment of chromosome localizationGO:0051303200.019
Yeast
positive regulation of transportGO:00510503360.019
positive regulation of hydrolase activityGO:00513453310.019
atp metabolic processGO:00460341760.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
negative regulation of proteasomal protein catabolic processGO:1901799320.019
Yeast
spindle stabilizationGO:004314640.019
regulation of nucleocytoplasmic transportGO:0046822980.019
regulation of cell cycle phase transitionGO:19019871260.019
Yeast Zebrafish
photoreceptor cell differentiationGO:004653020.019
ribosome assemblyGO:004225590.018
forebrain developmentGO:0030900260.018
negative regulation of protein maturationGO:19033181420.018
Yeast
positive regulation of protein transportGO:00512221350.018
negative regulation of catalytic activityGO:00430863350.018
regulation of establishment of protein localizationGO:00702012420.018
positive regulation of gtp catabolic processGO:00331261660.018
protein complex disassemblyGO:0043241520.018
positive regulation of protein kinase activityGO:00458601900.018
regulation of chromosome organizationGO:00330441030.017
Yeast
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.017
Yeast
regulation of protein transportGO:00512232130.017
regulation of meiotic cell cycleGO:005144540.017
negative regulation of cellular protein metabolic processGO:00322693530.017
Yeast
spindle checkpointGO:0031577260.017
Yeast
head developmentGO:00603221080.017
positive regulation of cell developmentGO:0010720920.017
embryonic epithelial tube formationGO:000183840.017
mitotic metaphase plate congressionGO:0007080140.017
Yeast
regulation of protein stabilityGO:0031647870.017
regulation of intracellular transportGO:00323861950.017
protein targetingGO:00066051870.017
ubiquitin dependent protein catabolic processGO:00065112060.017
Yeast
protein dephosphorylationGO:0006470810.016
central nervous system developmentGO:00074171230.016
positive regulation of mitotic cell cycleGO:0045931600.016
macromolecular complex disassemblyGO:0032984600.016
purine nucleotide catabolic processGO:00061954050.016
regulation of response to dna damage stimulusGO:2001020940.016
cell projection organizationGO:00300302520.016
chordate embryonic developmentGO:0043009340.016
biological adhesionGO:00226103310.016
positive regulation of cell divisionGO:0051781590.016
regulation of dna bindingGO:0051101370.015
regulation of protein complex assemblyGO:00432541470.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
microtubule bundle formationGO:0001578150.015
brain developmentGO:0007420970.015
positive regulation of cell differentiationGO:00455972110.015
negative regulation of chromosome organizationGO:2001251480.015
Yeast
positive regulation of gtpase activityGO:00435471660.015
nucleotide catabolic processGO:00091664080.015
guanosine containing compound catabolic processGO:19010692390.015
brain morphogenesisGO:004885410.015
positive regulation of nucleotide metabolic processGO:00459812300.014
positive regulation of kinase activityGO:00336742040.014
kinetochore organizationGO:005138380.014
positive regulation of transferase activityGO:00513472270.014
meiotic cell cycle processGO:190304680.014
Zebrafish
intracellular protein transportGO:00068862700.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
double strand break repair via homologous recombinationGO:0000724500.014
positive regulation of cellular protein catabolic processGO:1903364370.014
establishment of spindle localizationGO:0051293120.014
regulation of double strand break repairGO:2000779220.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
cellular component disassemblyGO:0022411920.014
response to organic cyclic compoundGO:00140702040.014
protein oligomerizationGO:00512591730.014
regulation of dna metabolic processGO:00510521530.014
negative regulation of cellular protein catabolic processGO:1903363380.014
Yeast
regulation of cellular component biogenesisGO:00440872810.013
spindle assembly checkpointGO:0071173170.013
Yeast
response to oxidative stressGO:00069791210.013
cdc42 protein signal transductionGO:003248840.013
regulation of protein localization to nucleusGO:1900180850.013
primary neural tube formationGO:001402030.013
telencephalon developmentGO:0021537170.013
regulation of ras protein signal transductionGO:00465781550.013
regulation of cellular component movementGO:00512703340.013
cell cycle checkpointGO:00000751170.013
Yeast Zebrafish
growthGO:00400072020.013
Zebrafish
actin filament based processGO:00300292240.013
protein importGO:00170381300.013
oocyte maturationGO:000155610.013
cell part morphogenesisGO:00329901370.013
cellular amine metabolic processGO:0044106410.013
spermatid differentiationGO:004851540.013
regulation of protein ubiquitinationGO:0031396950.013
regulation of protein serine threonine kinase activityGO:00719001790.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
establishment of protein localization to organelleGO:00725941720.012
negative regulation of cytoskeleton organizationGO:0051494450.012
cellular response to endogenous stimulusGO:00714953360.012
positive regulation of cytoplasmic transportGO:1903651820.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
positive regulation of protein import into nucleusGO:0042307460.012
positive regulation of ras gtpase activityGO:00323201170.012
atp catabolic processGO:00062001570.012
regulation of nucleotide metabolic processGO:00061402690.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
regulation of protein targetingGO:1903533910.012
regulation of cell morphogenesisGO:00226041530.012
regulation of protein import into nucleusGO:0042306780.011
negative regulation of chromosome segregationGO:0051985180.011
Yeast
cell morphogenesis involved in differentiationGO:00009041440.011
endomembrane system organizationGO:00102561960.011
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of endopeptidase activityGO:00525481700.011
negative regulation of mitotic sister chromatid separationGO:2000816170.011
Yeast
regulation of neural precursor cell proliferationGO:200017740.011
reproductionGO:0000003630.011
Zebrafish
negative regulation of catabolic processGO:00098951040.011
Yeast
peptidyl lysine modificationGO:00182051440.011
cell adhesionGO:00071553250.011
cellular response to oxidative stressGO:0034599850.011
cell cycle phase transitionGO:00447701730.011
Yeast Zebrafish
vesicle transport along microtubuleGO:004749640.011
centromeric sister chromatid cohesionGO:007060130.011
negative regulation of mitotic cell cycleGO:00459301020.011
Yeast Zebrafish
positive regulation of purine nucleotide catabolic processGO:00331231850.011
regulation of neurogenesisGO:0050767820.011
apoptotic signaling pathwayGO:00971902680.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
regulation of protein maturationGO:19033171500.011
Yeast
regulation of cellular response to stressGO:00801352440.011
cell projection morphogenesisGO:00488581290.010
double strand break repairGO:00063021010.010
regulation of peptidase activityGO:00525471800.010
agingGO:0007568660.010
positive regulation of intracellular transportGO:00323881040.010
chromosome condensationGO:0030261150.010
nuclear importGO:00511701060.010
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.010
Yeast
guanosine containing compound metabolic processGO:19010682440.010
amine metabolic processGO:0009308440.010
cellular response to abiotic stimulusGO:00712141170.010

TTK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.031
physical disorderDOID:0080015410.027
congenital nervous system abnormalityDOID:2490210.027
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015