Homo sapiens

139 known processes

FXN

frataxin

(Aliases: MGC57199,FRDA,CyaY,FA,FARR,X25)

FXN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.201
cellular amino acid metabolic processGO:00065201160.122
cellular ketone metabolic processGO:0042180800.080
ribonucleoside monophosphate metabolic processGO:00091611870.074
Mouse
ion transmembrane transportGO:00342203380.070
purine ribonucleoside metabolic processGO:00461284370.068
Mouse
organonitrogen compound biosynthetic processGO:19015662000.065
purine ribonucleoside monophosphate metabolic processGO:00091671860.064
Mouse
transmembrane transportGO:00550853990.062
locomotory behaviorGO:000762610.058
Mouse
nucleoside phosphate biosynthetic processGO:19012931090.052
single organism membrane organizationGO:00448022680.048
amine metabolic processGO:0009308440.047
determination of adult lifespanGO:000834020.046
nucleoside triphosphate metabolic processGO:00091414220.046
Mouse
cellular amine metabolic processGO:0044106410.045
purine nucleoside monophosphate metabolic processGO:00091261860.039
Mouse
vesicle mediated transportGO:00161923710.039
nucleotide biosynthetic processGO:00091651090.038
atp metabolic processGO:00460341760.038
Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.037
Mouse
female gamete generationGO:000729220.037
lipid metabolic processGO:00066293810.037
multicellular organismal agingGO:001025930.036
regulation of cellular ketone metabolic processGO:0010565500.036
cellular component morphogenesisGO:00329893140.036
cation transmembrane transportGO:00986552380.036
mitochondrion organizationGO:00070051560.034
purine nucleoside triphosphate metabolic processGO:00091444120.033
Mouse
response to oxygen containing compoundGO:19017003690.032
membrane organizationGO:00610242920.032
nucleoside monophosphate metabolic processGO:00091231910.032
Mouse
protein maturationGO:00516042330.031
regulation of cellular amino acid metabolic processGO:000652160.029
cellular macromolecule catabolic processGO:00442653800.029
regulation of nucleotide metabolic processGO:00061402690.028
response to abiotic stimulusGO:00096283360.028
regulation of cellular amine metabolic processGO:0033238110.027
positive regulation of cellular component organizationGO:00511303760.027
protein localization to organelleGO:00333652800.026
alpha amino acid metabolic processGO:1901605720.026
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.026
nucleoside triphosphate catabolic processGO:00091433940.026
positive regulation of hydrolase activityGO:00513453310.026
generation of precursor metabolites and energyGO:0006091680.026
Mouse
glutamine family amino acid metabolic processGO:0009064170.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
positive regulation of transportGO:00510503360.026
intracellular protein transportGO:00068862700.025
secretion by cellGO:00329402260.025
anterior posterior axis specificationGO:000994820.024
negative regulation of cell proliferationGO:00082852280.024
carbohydrate metabolic processGO:00059752070.024
negative regulation of multicellular organismal processGO:00512413170.024
Mouse
nucleoside phosphate catabolic processGO:19012924120.024
response to oxygen levelsGO:00704821000.023
regulation of kinase activityGO:00435493140.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
Mouse
regenerationGO:003109940.023
inorganic cation transmembrane transportGO:00986621940.023
negative regulation of cellular protein metabolic processGO:00322693530.023
cofactor metabolic processGO:0051186870.023
response to decreased oxygen levelsGO:0036293960.023
regulation of cell growthGO:00015581350.022
positive regulation of cell proliferationGO:00082843010.022
nitrogen compound transportGO:00717051910.022
negative regulation of protein metabolic processGO:00512483910.022
single organism cellular localizationGO:19025803320.022
regulation of nucleoside metabolic processGO:00091182090.022
small molecule biosynthetic processGO:00442831570.022
regulation of proteolysisGO:00301622930.022
negative regulation of programmed cell deathGO:00430693210.022
actin filament based processGO:00300292240.022
small molecule catabolic processGO:0044282920.022
covalent chromatin modificationGO:00165692540.022
organophosphate biosynthetic processGO:00904071630.022
cellular macromolecular complex assemblyGO:00346223240.021
single organism carbohydrate metabolic processGO:00447231930.021
protein catabolic processGO:00301633250.021
positive regulation of developmental processGO:00510943140.021
cytoplasmic transportGO:00164823790.021
negative regulation of cell deathGO:00605483450.021
purine containing compound biosynthetic processGO:0072522880.021
purine containing compound catabolic processGO:00725234110.021
nucleotide catabolic processGO:00091664080.021
organophosphate catabolic processGO:00464344300.020
immune responseGO:00069553070.020
cellular lipid metabolic processGO:00442553030.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
negative regulation of catalytic activityGO:00430863350.020
positive regulation of cell deathGO:00109422630.020
oxidation reduction processGO:00551143960.020
positive regulation of organelle organizationGO:00106381950.020
positive regulation of programmed cell deathGO:00430682490.020
regulation of growthGO:00400081650.019
cellular response to dna damage stimulusGO:00069743790.019
oogenesisGO:004847720.019
carbohydrate derivative biosynthetic processGO:19011372070.019
biological adhesionGO:00226103310.019
posttranscriptional regulation of gene expressionGO:00106082130.019
mitotic cell cycle processGO:19030472860.019
purine nucleotide biosynthetic processGO:0006164840.019
inorganic ion transmembrane transportGO:00986602310.019
growthGO:00400072020.018
histone modificationGO:00165702510.018
embryo developmentGO:00097901230.018
Mouse
adult locomotory behaviorGO:000834410.018
Mouse
negative regulation of protein modification processGO:00314002000.018
apoptotic signaling pathwayGO:00971902680.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
nervous system developmentGO:00073992930.018
negative regulation of phosphorus metabolic processGO:00105632670.018
establishment of protein localization to organelleGO:00725941720.018
anion transmembrane transportGO:0098656760.018
segmentationGO:003528240.018
protein homooligomerizationGO:00512601000.018
ribonucleotide catabolic processGO:00092614050.018
protein localization to membraneGO:00726571600.018
regulation of peptidase activityGO:00525471800.018
protein processingGO:00164852260.017
cell growthGO:00160491600.017
actin cytoskeleton organizationGO:00300362070.017
cation transportGO:00068123310.017
monovalent inorganic cation transportGO:00156721280.017
ribose phosphate biosynthetic processGO:0046390820.017
positive regulation of cellular amine metabolic processGO:003324070.017
coenzyme metabolic processGO:0006732650.017
cytokine productionGO:00018162470.017
cell projection organizationGO:00300302520.017
negative regulation of hydrolase activityGO:00513461820.017
response to cytokineGO:00340972320.017
protein ubiquitinationGO:00165673140.017
nucleocytoplasmic transportGO:00069131760.017
organic acid transportGO:0015849650.017
purine ribonucleoside catabolic processGO:00461303980.017
intracellular receptor signaling pathwayGO:00305221040.016
ribonucleoside catabolic processGO:00424544060.016
regulation of cell differentiationGO:00455953930.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of phosphate metabolic processGO:00459362670.016
negative regulation of organelle organizationGO:00106391260.016
defense responseGO:00069523150.016
mitochondrial membrane organizationGO:0007006400.016
mitotic cell cycleGO:00002783260.016
lipid biosynthetic processGO:00086101770.016
negative regulation of intracellular signal transductionGO:19025321830.016
nuclear transportGO:00511691790.016
regulation of cellular response to stressGO:00801352440.016
metal ion transportGO:00300012720.016
protein targetingGO:00066051870.016
neuromuscular junction developmentGO:000752830.016
regulation of transmembrane transportGO:00347621390.016
regulation of anatomical structure morphogenesisGO:00226032860.016
negative regulation of cellular component organizationGO:00511292350.016
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of cellular component movementGO:00512703340.015
regulation of immune responseGO:00507762010.015
regulation of feeding behaviorGO:006025930.015
myosin filament assemblyGO:003103420.015
protein oligomerizationGO:00512591730.015
response to external biotic stimulusGO:00432072610.015
regulation of ion transportGO:00432691890.015
cell adhesionGO:00071553250.015
regulation of membrane potentialGO:0042391950.015
secretionGO:00469032540.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
carboxylic acid biosynthetic processGO:0046394970.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
regulation of cytokine productionGO:00018172320.015
cellular response to oxygen levelsGO:0071453550.015
cellular metal ion homeostasisGO:00068751460.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of locomotionGO:00400171860.015
endocytosisGO:00068971590.014
cell morphogenesisGO:00009022960.014
response to other organismGO:00517072610.014
cellular response to oxygen containing compoundGO:19017012760.014
organic acid biosynthetic processGO:0016053970.014
nucleoside catabolic processGO:00091644080.014
cellular response to decreased oxygen levelsGO:0036294510.014
maintenance of locationGO:00512351120.014
response to oxidative stressGO:00069791210.014
organic anion transportGO:00157111030.014
divalent metal ion transportGO:00708381520.014
negative regulation of cell cycleGO:00457861930.014
cellular response to cytokine stimulusGO:00713451810.014
translationGO:00064121320.014
small gtpase mediated signal transductionGO:0007264780.014
purine nucleoside catabolic processGO:00061523980.014
blastoderm segmentationGO:000735020.014
organic acid catabolic processGO:0016054710.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
response to organic cyclic compoundGO:00140702040.013
regulation of protein localizationGO:00328802960.013
hindbrain developmentGO:003090230.013
positive regulation of cellular catabolic processGO:00313312840.013
hemopoiesisGO:00300971800.013
dna conformation changeGO:00711031130.013
regulation of apoptotic signaling pathwayGO:20012331750.013
cell developmentGO:00484683280.013
response to biotic stimulusGO:00096072760.013
developmental programmed cell deathGO:001062330.013
cell cell signalingGO:00072671550.013
positive regulation of cell migrationGO:00303351720.013
glycosyl compound catabolic processGO:19016584130.012
protein tetramerizationGO:0051262470.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
pharynx developmentGO:006046510.012
ion homeostasisGO:00508012300.012
regulation of oxidative phosphorylationGO:000208230.012
cellular amino acid biosynthetic processGO:0008652300.012
positive regulation of immune responseGO:00507781590.012
cellular protein complex assemblyGO:00436231880.012
cell substrate adhesionGO:00315891320.012
negative regulation of phosphorylationGO:00423261740.012
ras protein signal transductionGO:0007265730.012
cellular homeostasisGO:00197251960.012
positive regulation of immune system processGO:00026842830.012
regulation of defense responseGO:00313471540.012
tripartite regional subdivisionGO:000735120.012
regulation of protein kinase activityGO:00458592890.012
regulation of dna metabolic processGO:00510521530.012
cell activationGO:00017752130.012
oocyte differentiationGO:000999420.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of behaviorGO:0050795820.012
positive regulation of catabolic processGO:00098963100.012
regulation of generation of precursor metabolites and energyGO:0043467270.012
positive regulation of cell differentiationGO:00455972110.012
carboxylic acid catabolic processGO:0046395710.012
central nervous system developmentGO:00074171230.012
protein autophosphorylationGO:00467771230.012
regulation of response to external stimulusGO:00321012220.012
innate immune responseGO:00450871780.012
purine ribonucleotide catabolic processGO:00091544040.012
phospholipid metabolic processGO:0006644990.012
regulation of protein stabilityGO:0031647870.012
ribonucleotide biosynthetic processGO:0009260810.012
anterior posterior axis specification embryoGO:000859520.011
regulation of protein catabolic processGO:00421761550.011
cofactor biosynthetic processGO:0051188310.011
receptor metabolic processGO:0043112810.011
modification dependent macromolecule catabolic processGO:00436322120.011
monocarboxylic acid metabolic processGO:00327871850.011
oocyte developmentGO:004859910.011
immune system developmentGO:00025201950.011
chemical homeostasisGO:00488783060.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
lymphocyte activationGO:00466491330.011
regulation of intracellular transportGO:00323861950.011
response to nitrogen compoundGO:19016981840.011
zymogen activationGO:0031638700.011
negative regulation of growthGO:0045926970.011
Mouse
cellular cation homeostasisGO:00300031630.011
regulation of protein processingGO:00706131500.011
protein modification by small protein conjugationGO:00324463420.011
mitochondrial transportGO:0006839600.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
spermatid differentiationGO:004851540.011
regulation of transferase activityGO:00513383550.011
activation of immune responseGO:00022531140.011
cell type specific apoptotic processGO:00972851250.011
regulation of establishment of protein localizationGO:00702012420.011
regulation of ion transmembrane transportGO:00347651320.011
ossificationGO:00015031210.011
positive regulation of peptidase activityGO:0010952880.011
protein secretionGO:0009306980.011
organelle assemblyGO:00709251760.011
negative regulation of immune system processGO:00026831360.011
negative regulation of cell growthGO:0030308830.011
negative regulation of cellular amine metabolic processGO:003323930.010
regulation of protein maturationGO:19033171500.010
cellular amino acid catabolic processGO:0009063310.010
negative regulation of transportGO:00510511760.010
positive regulation of cytokine productionGO:00018191670.010
endomembrane system organizationGO:00102561960.010
cellular protein catabolic processGO:00442572610.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
regulation of response to woundingGO:19030341010.010
cell part morphogenesisGO:00329901370.010
dephosphorylationGO:00163112090.010
i kappab kinase nf kappab signalingGO:00072491660.010
cellular component disassemblyGO:0022411920.010
response to hypoxiaGO:0001666960.010
protein homotetramerizationGO:0051289280.010
positive regulation of cysteine type endopeptidase activityGO:2001056790.010
reactive oxygen species metabolic processGO:0072593750.010
compound eye developmentGO:004874910.010
positive regulation of endopeptidase activityGO:0010950840.010
response to organonitrogen compoundGO:00102431560.010
immune response regulating signaling pathwayGO:0002764970.010

FXN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.383
disease of metabolismDOID:00146672950.383
disease of cellular proliferationDOID:145661740.043
cancerDOID:1621670.043
central nervous system diseaseDOID:3311860.041
nervous system diseaseDOID:8634310.041
organ system cancerDOID:00506861640.040
amino acid metabolic disorderDOID:9252500.037
sensory system diseaseDOID:00501552030.010
neurodegenerative diseaseDOID:12891020.010
spinocerebellar degenerationDOID:2478270.003
spinocerebellar ataxiaDOID:1441260.003