Homo sapiens

29 known processes

DFNB31

deafness, autosomal recessive 31

(Aliases: USH2D,CIP98,DKFZp434N014,WI,KIAA1526,WHRN)

DFNB31 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.067
cellular ketone metabolic processGO:0042180800.067
regulation of cellular amino acid metabolic processGO:000652160.062
amine metabolic processGO:0009308440.061
positive regulation of cellular amino acid metabolic processGO:004576430.059
regulation of cellular amine metabolic processGO:0033238110.059
cellular amino acid metabolic processGO:00065201160.059
positive regulation of cellular amine metabolic processGO:003324070.054
cellular amine metabolic processGO:0044106410.053
regulation of cellular ketone metabolic processGO:0010565500.053
neuromuscular junction developmentGO:000752830.050
positive regulation of cellular component organizationGO:00511303760.046
postsynaptic membrane organizationGO:000194120.042
multicellular organismal agingGO:001025930.040
cellular component morphogenesisGO:00329893140.039
cation transportGO:00068123310.039
metal ion transportGO:00300012720.037
determination of adult lifespanGO:000834020.037
positive regulation of phosphorylationGO:00423273940.036
system processGO:00030083490.035
locomotory behaviorGO:000762610.034
regulation of cell cycleGO:00517263930.034
negative regulation of protein metabolic processGO:00512483910.033
secretionGO:00469032540.033
transmembrane transportGO:00550853990.033
negative regulation of catalytic activityGO:00430863350.032
single organism cellular localizationGO:19025803320.032
cell projection organizationGO:00300302520.032
Mouse
single organism membrane organizationGO:00448022680.032
cell morphogenesisGO:00009022960.031
regulation of cell differentiationGO:00455953930.031
ras protein signal transductionGO:0007265730.031
regulation of transferase activityGO:00513383550.031
negative regulation of phosphate metabolic processGO:00459362670.030
negative regulation of cellular protein metabolic processGO:00322693530.030
oogenesisGO:004847720.030
cell developmentGO:00484683280.030
Mouse
membrane organizationGO:00610242920.030
negative regulation of axonogenesisGO:005077140.030
ribonucleoside catabolic processGO:00424544060.029
nucleotide catabolic processGO:00091664080.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
nucleoside triphosphate metabolic processGO:00091414220.029
small gtpase mediated signal transductionGO:0007264780.029
positive regulation of protein phosphorylationGO:00019343130.029
female gamete generationGO:000729220.028
purine nucleotide catabolic processGO:00061954050.028
biological adhesionGO:00226103310.028
organonitrogen compound biosynthetic processGO:19015662000.028
purine containing compound catabolic processGO:00725234110.028
carbohydrate derivative biosynthetic processGO:19011372070.027
regulation of kinase activityGO:00435493140.027
purine ribonucleoside catabolic processGO:00461303980.027
cytoplasmic transportGO:00164823790.027
regulation of protein localizationGO:00328802960.027
negative regulation of phosphorus metabolic processGO:00105632670.027
organophosphate catabolic processGO:00464344300.027
mitotic cell cycle processGO:19030472860.027
Human
chemical homeostasisGO:00488783060.027
ribonucleoside triphosphate catabolic processGO:00092033910.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
cell adhesionGO:00071553250.026
cellular macromolecule catabolic processGO:00442653800.026
negative regulation of programmed cell deathGO:00430693210.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
nucleoside phosphate catabolic processGO:19012924120.026
signal transduction by phosphorylationGO:00230142970.026
protein localization to organelleGO:00333652800.026
regulation of anatomical structure morphogenesisGO:00226032860.026
ribonucleotide catabolic processGO:00092614050.025
negative regulation of cellular component organizationGO:00511292350.025
wnt signaling pathwayGO:00160551560.025
negative regulation of multicellular organismal processGO:00512413170.025
purine ribonucleoside metabolic processGO:00461284370.025
nervous system developmentGO:00073992930.025
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
memoryGO:000761330.024
purine nucleoside catabolic processGO:00061523980.024
negative regulation of apoptotic processGO:00430663160.024
intracellular protein transportGO:00068862700.024
negative regulation of cell deathGO:00605483450.024
vesicle mediated transportGO:00161923710.024
peripheral nervous system developmentGO:000742220.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
negative regulation of protein modification processGO:00314002000.023
regulation of nucleotide metabolic processGO:00061402690.023
segmentationGO:003528240.023
glycosyl compound catabolic processGO:19016584130.023
regulation of cell morphogenesisGO:00226041530.023
positive regulation of catabolic processGO:00098963100.023
nucleoside triphosphate catabolic processGO:00091433940.023
retina vasculature morphogenesis in camera type eyeGO:006129930.023
immune responseGO:00069553070.023
regulation of proteolysisGO:00301622930.023
carbohydrate metabolic processGO:00059752070.023
nucleoside catabolic processGO:00091644080.023
protein catabolic processGO:00301633250.022
anion transportGO:00068201610.022
positive regulation of transportGO:00510503360.022
positive regulation of hydrolase activityGO:00513453310.022
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
regulation of protein kinase activityGO:00458592890.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
cellular response to oxygen containing compoundGO:19017012760.022
mitotic cell cycleGO:00002783260.022
Human
protein localization to membraneGO:00726571600.022
regulation of sequence specific dna binding transcription factor activityGO:00510902110.022
regulation of secretionGO:00510461940.022
morphogenesis of embryonic epitheliumGO:001633140.022
regulation of establishment of protein localizationGO:00702012420.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
negative regulation of developmental processGO:00510932470.021
ion transmembrane transportGO:00342203380.021
cellular macromolecular complex assemblyGO:00346223240.021
regulation of purine nucleotide metabolic processGO:19005422640.021
adult locomotory behaviorGO:000834410.021
purine ribonucleotide catabolic processGO:00091544040.021
positive regulation of cell proliferationGO:00082843010.021
mapk cascadeGO:00001652880.021
guanosine containing compound catabolic processGO:19010692390.020
positive regulation of organelle organizationGO:00106381950.020
calcium ion transportGO:00068161470.020
protein modification by small protein conjugationGO:00324463420.020
positive regulation of kinase activityGO:00336742040.020
gtp catabolic processGO:00061842370.020
growthGO:00400072020.020
gtp metabolic processGO:00460392390.019
regenerationGO:003109940.019
epithelium developmentGO:00604292270.019
response to oxygen containing compoundGO:19017003690.019
microtubule based processGO:00070172100.019
protein maturationGO:00516042330.019
positive regulation of transferase activityGO:00513472270.019
positive regulation of cellular catabolic processGO:00313312840.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
single organism carbohydrate metabolic processGO:00447231930.019
divalent metal ion transportGO:00708381520.019
neurogenesisGO:00220081690.019
Mouse
regulation of cell adhesionGO:00301551660.019
regulation of protein transportGO:00512232130.019
apoptotic signaling pathwayGO:00971902680.019
positive regulation of developmental processGO:00510943140.019
regulation of intracellular transportGO:00323861950.019
regulation of mapk cascadeGO:00434082620.019
positive regulation of protein kinase activityGO:00458601900.019
regulation of nucleotide catabolic processGO:00308112050.019
protein ubiquitinationGO:00165673140.019
establishment of protein localization to organelleGO:00725941720.018
cellular response to dna damage stimulusGO:00069743790.018
regulation of locomotionGO:00400123290.018
neuroblast proliferationGO:000740540.018
blastoderm segmentationGO:000735020.018
protein targetingGO:00066051870.018
regulation of transmembrane transportGO:00347621390.018
regulation of mitotic cell cycleGO:00073461890.018
negative regulation of cell proliferationGO:00082852280.018
maintenance of locationGO:00512351120.018
peptidyl tyrosine phosphorylationGO:00181081700.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
mitotic nuclear divisionGO:00070671190.018
positive regulation of nucleotide metabolic processGO:00459812300.018
guanosine containing compound metabolic processGO:19010682440.018
cell fate determinationGO:000170930.017
response to abiotic stimulusGO:00096283360.017
protein processingGO:00164852260.017
negative regulation of cellular amine metabolic processGO:003323930.017
organelle assemblyGO:00709251760.017
forebrain generation of neuronsGO:002187230.017
dephosphorylationGO:00163112090.017
positive regulation of cell differentiationGO:00455972110.017
divalent inorganic cation transportGO:00725111580.017
regulation of cell cycle processGO:00105642660.017
secretion by cellGO:00329402260.017
generation of neuronsGO:00486991520.017
Mouse
limbic system developmentGO:002176130.017
oocyte developmentGO:004859910.017
cell morphogenesis involved in differentiationGO:00009041440.017
cellular protein catabolic processGO:00442572610.017
negative regulation of hydrolase activityGO:00513461820.017
neurological system processGO:00508771630.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
chromatin organizationGO:00063253510.017
cell divisionGO:00513011680.017
regulation of cellular component biogenesisGO:00440872810.017
regulation of cell growthGO:00015581350.017
cellular lipid metabolic processGO:00442553030.017
cardiovascular system developmentGO:00723582620.017
regulation of cell developmentGO:00602841610.017
spermatid differentiationGO:004851540.017
hindbrain developmentGO:003090230.017
rho protein signal transductionGO:0007266260.017
cell type specific apoptotic processGO:00972851250.016
regulation of nucleoside metabolic processGO:00091182090.016
oocyte differentiationGO:000999420.016
chromatin modificationGO:00165682980.016
cell part morphogenesisGO:00329901370.016
circulatory system developmentGO:00723592620.016
cell growthGO:00160491600.016
negative regulation of phosphorylationGO:00423261740.016
regulation of cellular response to stressGO:00801352440.016
regulation of gtp catabolic processGO:00331241800.016
endomembrane system organizationGO:00102561960.016
cell projection morphogenesisGO:00488581290.016
lipid metabolic processGO:00066293810.016
negative regulation of cell cycleGO:00457861930.016
neurotransmitter secretionGO:000726940.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
positive regulation of cell deathGO:00109422630.016
embryonic epithelial tube formationGO:000183840.016
defense responseGO:00069523150.016
positive regulation of mesenchymal cell proliferationGO:000205320.016
regulation of synaptic plasticityGO:004816730.016
proteasomal protein catabolic processGO:00104981760.016
osteoblast differentiationGO:0001649920.016
negative regulation of transportGO:00510511760.016
protein localization to nucleusGO:00345041360.016
regulation of cell migrationGO:00303342890.016
response to lipidGO:00339932060.016
organic anion transportGO:00157111030.016
histone modificationGO:00165702510.016
positive regulation of nucleoside metabolic processGO:00459791860.016
modification dependent macromolecule catabolic processGO:00436322120.015
regulation of growthGO:00400081650.015
positive regulation of cell cycleGO:00457871400.015
ossificationGO:00015031210.015
regulation of response to external stimulusGO:00321012220.015
nucleocytoplasmic transportGO:00069131760.015
positive regulation of mapk cascadeGO:00434101900.015
regulation of wnt signaling pathwayGO:00301111230.015
nitrogen compound transportGO:00717051910.015
cellular protein complex assemblyGO:00436231880.015
tissue morphogenesisGO:0048729960.015
spermatid developmentGO:000728640.015
positive regulation of synaptic transmissionGO:005080640.015
regulation of protein serine threonine kinase activityGO:00719001790.015
positive regulation of nucleotide catabolic processGO:00308131850.015
negative regulation of cell differentiationGO:00455961710.015
organophosphate biosynthetic processGO:00904071630.015
positive regulation of apoptotic processGO:00430652460.015
regulation of neural precursor cell proliferationGO:200017740.015
organ morphogenesisGO:00098871470.015
regulation of cell morphogenesis involved in differentiationGO:0010769830.015
microtubule cytoskeleton organizationGO:00002261760.015
negative regulation of transferase activityGO:00513481240.015
cell substrate adhesionGO:00315891320.015
cell projection assemblyGO:00300311260.015
motor neuron axon guidanceGO:000804520.015
nuclear transportGO:00511691790.015
regulation of neurotransmitter secretionGO:004692830.015
actin filament based processGO:00300292240.015
neuron developmentGO:00486661130.014
Mouse
matingGO:000761810.014
ubiquitin dependent protein catabolic processGO:00065112060.014
anterior posterior axis specificationGO:000994820.014
regulation of gtpase activityGO:00430871800.014
response to external biotic stimulusGO:00432072610.014
modification dependent protein catabolic processGO:00199412090.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
protein oligomerizationGO:00512591730.014
salivary gland morphogenesisGO:000743540.014
embryonic morphogenesisGO:0048598850.014
positive regulation of gtp catabolic processGO:00331261660.014
regulation of cytoplasmic transportGO:19036491490.014
retina vasculature development in camera type eyeGO:006129830.014
positive regulation of programmed cell deathGO:00430682490.014
morphogenesis of a polarized epitheliumGO:000173830.014
compound eye developmentGO:004874910.014
taxisGO:00423301570.014
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.014
covalent chromatin modificationGO:00165692540.014
atp metabolic processGO:00460341760.014
actin cytoskeleton organizationGO:00300362070.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
response to biotic stimulusGO:00096072760.014
inner ear morphogenesisGO:004247240.014
regulation of neuron differentiationGO:0045664700.014
regulation of cytoskeleton organizationGO:00514931770.014
negative regulation of intracellular signal transductionGO:19025321830.014
cell cycle phase transitionGO:00447701730.013
Human
response to organic cyclic compoundGO:00140702040.013
cellular response to endogenous stimulusGO:00714953360.013
small molecule biosynthetic processGO:00442831570.013
canonical wnt signaling pathwayGO:00600701160.013
mitochondrion organizationGO:00070051560.013
regulation of intracellular protein transportGO:00331571230.013
tripartite regional subdivisionGO:000735120.013
regulation of cell projection organizationGO:00313441070.013
mitotic cell cycle phase transitionGO:00447721620.013
Human
regulation of nervous system developmentGO:0051960880.013
anterior posterior axis specification embryoGO:000859520.013
cilium morphogenesisGO:0060271750.013
endosomal transportGO:00161971290.013
presynaptic membrane assemblyGO:009710510.013
innate immune responseGO:00450871780.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
negative regulation of canonical wnt signaling pathwayGO:0090090550.013
regulation of peptidase activityGO:00525471800.013
posttranscriptional regulation of gene expressionGO:00106082130.013
positive regulation of cellular component movementGO:00512721810.013
regulation of hormone levelsGO:00108171250.013
regulation of neurogenesisGO:0050767820.013
circulatory system processGO:00030131130.013
regulation of cell motilityGO:20001452990.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
positive regulation of gtpase activityGO:00435471660.013
negative regulation of wnt signaling pathwayGO:0030178690.013
neural tube formationGO:000184130.013
nerve developmentGO:002167540.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
presynaptic membrane organizationGO:009709030.013
immune system developmentGO:00025201950.013
regulation of protein maturationGO:19033171500.013
cation homeostasisGO:00550801890.013
regulation of cellular component movementGO:00512703340.013
neuron projection developmentGO:00311751060.013
regulation of apoptotic signaling pathwayGO:20012331750.013
response to fungusGO:000962040.013
monosaccharide metabolic processGO:0005996740.013
cellular homeostasisGO:00197251960.012
negative regulation of protein phosphorylationGO:00019331400.012
cellular response to lipidGO:00713961270.012
blood vessel developmentGO:00015681720.012
organ formationGO:004864530.012
chemotaxisGO:00069351570.012
regulation of ras gtpase activityGO:00323181280.012
reactive oxygen species biosynthetic processGO:190340940.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
rhythmic behaviorGO:000762220.012
regulation of synaptic vesicle transportGO:190280330.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
protein importGO:00170381300.012
regulation of protein processingGO:00706131500.012
regulation of ras protein signal transductionGO:00465781550.012
meiotic chromosome segregationGO:004513240.012
regulation of purine nucleotide catabolic processGO:00331212050.012
nuclear importGO:00511701060.012
organelle fissionGO:00482851490.012
nucleoside monophosphate metabolic processGO:00091231910.012
long term memoryGO:000761620.012
response to growth factorGO:00708482050.012
blood vessel morphogenesisGO:00485141620.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
associative learningGO:000830610.012
positive regulation of cellular component biogenesisGO:00440891580.012
primary neural tube formationGO:001402030.012
negative regulation of kinase activityGO:00336731060.012
sex determinationGO:000753030.012
forebrain neuron differentiationGO:002187930.012
blood circulationGO:00080151130.012
regulation of protein targetingGO:1903533910.012
urogenital system developmentGO:0001655650.012
nuclear divisionGO:00002801280.012
cation transmembrane transportGO:00986552380.012
regulation of immune responseGO:00507762010.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
regulation of endopeptidase activityGO:00525481700.012
single organism cell adhesionGO:00986021790.012
neural crest cell developmentGO:001403230.012
regulation of protein catabolic processGO:00421761550.012
cilium organizationGO:0044782680.012
protein acylationGO:00435431380.012
regulation of cytokine productionGO:00018172320.012
ion homeostasisGO:00508012300.012
regulation of protein complex assemblyGO:00432541470.012
hematopoietic or lymphoid organ developmentGO:00485341860.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
regulation of cell divisionGO:00513021160.011
negative regulation of protein kinase activityGO:0006469980.011
positive regulation of immune system processGO:00026842830.011
negative regulation of organelle organizationGO:00106391260.011
cytokine productionGO:00018162470.011
syncytium formation by plasma membrane fusionGO:000076820.011
response to cytokineGO:00340972320.011
multi organism cellular processGO:00447641560.011
reactive oxygen species metabolic processGO:0072593750.011
regulation of vesicle mediated transportGO:00606271300.011
regulation of ion transportGO:00432691890.011
regulation of secretion by cellGO:19035301770.011
rna processingGO:00063962550.011
cellular response to organic cyclic compoundGO:00714071270.011
metencephalon developmentGO:002203720.011
protein heterotetramerizationGO:005129030.011
plasma membrane organizationGO:00070091150.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
dna repairGO:00062811980.011
cellular response to growth factor stimulusGO:00713631970.011
oxidation reduction processGO:00551143960.011
positive regulation of secretion by cellGO:19035321080.011
angiogenesisGO:00015251470.011
inorganic ion transmembrane transportGO:00986602310.011
response to axon injuryGO:004867810.011
protein targeting to nucleusGO:00447441040.011
regulation of meiotic cell cycleGO:005144540.011
regulation of multi organism processGO:00439001570.011
glycoprotein metabolic processGO:00091001100.011
rna interferenceGO:001624640.011
tissue regenerationGO:004224630.011
regulation of axon extension involved in axon guidanceGO:004884120.011
cardiac muscle cell contractionGO:008600340.011
positive regulation of cell cycle processGO:00900681060.011
embryonic placenta developmentGO:000189210.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
reactive nitrogen species metabolic processGO:200105730.011
positive regulation of intracellular transportGO:00323881040.011
protein import into nucleusGO:00066061040.011
cellular response to cytokine stimulusGO:00713451810.011
positive regulation of cell migrationGO:00303351720.011
regulation of neuron projection developmentGO:0010975570.011
glycerolipid metabolic processGO:00464861070.011
circadian behaviorGO:004851220.010
tube closureGO:006060630.010
endocytosisGO:00068971590.010
vasculature developmentGO:00019441810.010
spinal cord developmentGO:002151040.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010
stem cell differentiationGO:0048863930.010
visual behaviorGO:000763220.010
response to woundingGO:00096111680.010
cilium assemblyGO:0042384630.010
neuron differentiationGO:00301821380.010
Mouse
photoreceptor cell differentiationGO:004653020.010
peptidyl tyrosine modificationGO:00182121700.010
negative regulation of growthGO:0045926970.010
lipid biosynthetic processGO:00086101770.010
peptidyl lysine modificationGO:00182051440.010
engulfment of apoptotic cellGO:004365220.010
neural tube closureGO:000184330.010
regulation of nucleocytoplasmic transportGO:0046822980.010
cellular chemical homeostasisGO:00550821800.010
negative regulation of cell growthGO:0030308830.010
negative regulation of protein maturationGO:19033181420.010
interspecies interaction between organismsGO:00444191560.010
establishment of protein localization to membraneGO:00901501210.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
negative regulation of protein processingGO:00109551420.010
establishment of tissue polarityGO:000716430.010

DFNB31 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.028
musculoskeletal system diseaseDOID:172230.027
sensory system diseaseDOID:00501552030.024
nervous system diseaseDOID:8634310.024
inherited metabolic disorderDOID:6552420.024
central nervous system diseaseDOID:3311860.021
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
neurodegenerative diseaseDOID:12891020.014
retinal diseaseDOID:56791180.014
primary ciliary dyskinesiaDOID:9562270.013
connective tissue diseaseDOID:651090.013
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
myopathyDOID:4231040.011
brain diseaseDOID:936730.011
retinal degenerationDOID:8466890.010
immune system diseaseDOID:29141550.010
auditory system diseaseDOID:2742530.008
nonsyndromic deafnessDOID:0050563500.008
autosomal recessive nonsyndromic deafnessDOID:0050565330.005
usher syndromeDOID:0050439120.002