Homo sapiens

42 known processes

HDAC8

histone deacetylase 8

(Aliases: HDACL1,RPD3,HD8)

HDAC8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
female gamete generationGO:000729220.112
post embryonic developmentGO:000979120.102
segmentationGO:003528240.097
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.082
blastoderm segmentationGO:000735020.080
oogenesisGO:004847720.077
regulation of cellular component biogenesisGO:00440872810.075
cardiac muscle contractionGO:0060048340.061
oocyte differentiationGO:000999420.059
cellular ketone metabolic processGO:0042180800.058
multicellular organismal agingGO:001025930.057
determination of adult lifespanGO:000834020.051
cellular amino acid metabolic processGO:00065201160.049
locomotory behaviorGO:000762610.047
oocyte developmentGO:004859910.047
anterior posterior axis specification embryoGO:000859520.046
regulation of cellular ketone metabolic processGO:0010565500.045
tripartite regional subdivisionGO:000735120.045
regulation of cellular amine metabolic processGO:0033238110.045
membrane organizationGO:00610242920.043
cellular amine metabolic processGO:0044106410.043
single organism cellular localizationGO:19025803320.042
amine metabolic processGO:0009308440.042
system processGO:00030083490.041
regulation of cellular amino acid metabolic processGO:000652160.041
regulation of cell differentiationGO:00455953930.039
purine ribonucleoside metabolic processGO:00461284370.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
mitochondrion organizationGO:00070051560.037
cell developmentGO:00484683280.037
single organism membrane organizationGO:00448022680.037
nucleoside triphosphate metabolic processGO:00091414220.036
cell morphogenesisGO:00009022960.035
organophosphate catabolic processGO:00464344300.035
nucleotide catabolic processGO:00091664080.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
purine ribonucleotide catabolic processGO:00091544040.034
organelle assemblyGO:00709251760.033
cellular component morphogenesisGO:00329893140.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
ribonucleoside triphosphate catabolic processGO:00092033910.032
cell projection organizationGO:00300302520.032
protein localization to organelleGO:00333652800.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
response to oxidative stressGO:00069791210.031
actin cytoskeleton organizationGO:00300362070.031
nervous system developmentGO:00073992930.031
purine nucleoside catabolic processGO:00061523980.031
cell projection assemblyGO:00300311260.031
ribonucleotide catabolic processGO:00092614050.030
cellular response to dna damage stimulusGO:00069743790.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
cellular response to oxidative stressGO:0034599850.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
muscle system processGO:0003012810.029
striated muscle contractionGO:0006941520.029
muscle contractionGO:0006936730.029
ribonucleoside catabolic processGO:00424544060.028
neuromuscular junction developmentGO:000752830.028
circulatory system developmentGO:00723592620.028
histone modificationGO:00165702510.028
neuron differentiationGO:00301821380.028
purine ribonucleoside catabolic processGO:00461303980.028
regulation of cell cycleGO:00517263930.028
purine containing compound catabolic processGO:00725234110.028
actin filament based processGO:00300292240.027
vesicle mediated transportGO:00161923710.027
nucleoside triphosphate catabolic processGO:00091433940.026
anatomical structure formation involved in morphogenesisGO:00486462840.026
negative regulation of protein metabolic processGO:00512483910.026
cardiovascular system developmentGO:00723582620.026
lipid biosynthetic processGO:00086101770.026
cellular component assembly involved in morphogenesisGO:0010927730.025
cellular macromolecular complex assemblyGO:00346223240.025
single organism reproductive processGO:0044702980.025
cellular lipid metabolic processGO:00442553030.025
positive regulation of catabolic processGO:00098963100.025
cellular protein catabolic processGO:00442572610.025
blood circulationGO:00080151130.024
cell part morphogenesisGO:00329901370.024
brain developmentGO:0007420970.024
regulation of protein localizationGO:00328802960.024
positive regulation of cellular amine metabolic processGO:003324070.024
cytoplasmic transportGO:00164823790.024
neuron projection developmentGO:00311751060.023
response to oxygen containing compoundGO:19017003690.023
ossificationGO:00015031210.023
response to abiotic stimulusGO:00096283360.023
cellular response to oxygen containing compoundGO:19017012760.023
lipid metabolic processGO:00066293810.022
cellular macromolecule catabolic processGO:00442653800.022
positive regulation of cellular component organizationGO:00511303760.022
nucleoside phosphate catabolic processGO:19012924120.022
covalent chromatin modificationGO:00165692540.022
intracellular mrna localizationGO:000829810.022
protein catabolic processGO:00301633250.022
regulation of proteolysisGO:00301622930.022
nucleoside catabolic processGO:00091644080.021
purine nucleotide catabolic processGO:00061954050.021
cellular homeostasisGO:00197251960.021
matingGO:000761810.021
meiosis iGO:000712740.021
negative regulation of developmental processGO:00510932470.021
protein processingGO:00164852260.021
reproductive processGO:00224141060.020
positive regulation of apoptotic processGO:00430652460.020
organophosphate biosynthetic processGO:00904071630.020
regulation of protein catabolic processGO:00421761550.020
negative regulation of cellular protein metabolic processGO:00322693530.020
osteoblast differentiationGO:0001649920.020
ubiquitin dependent protein catabolic processGO:00065112060.020
adult locomotory behaviorGO:000834410.020
cellular component disassemblyGO:0022411920.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of hydrolase activityGO:00513453310.019
generation of neuronsGO:00486991520.019
protein maturationGO:00516042330.019
regulation of cell cycle processGO:00105642660.019
positive regulation of cellular catabolic processGO:00313312840.019
modification dependent protein catabolic processGO:00199412090.019
central nervous system developmentGO:00074171230.019
transmembrane transportGO:00550853990.019
signal transduction by phosphorylationGO:00230142970.019
atp metabolic processGO:00460341760.018
positive regulation of transportGO:00510503360.018
protein targetingGO:00066051870.018
cell projection morphogenesisGO:00488581290.018
peripheral nervous system developmentGO:000742220.018
apoptotic signaling pathwayGO:00971902680.018
negative regulation of catalytic activityGO:00430863350.018
chromatin organizationGO:00063253510.018
positive regulation of phosphorylationGO:00423273940.018
cell morphogenesis involved in differentiationGO:00009041440.018
carbohydrate metabolic processGO:00059752070.018
microtubule based processGO:00070172100.017
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.017
negative regulation of organelle organizationGO:00106391260.017
single organism membrane fusionGO:0044801370.017
circulatory system processGO:00030131130.017
dna repairGO:00062811980.017
glycosyl compound catabolic processGO:19016584130.017
ras protein signal transductionGO:0007265730.017
small gtpase mediated signal transductionGO:0007264780.017
microtubule cytoskeleton organizationGO:00002261760.017
dephosphorylationGO:00163112090.017
cellular response to reactive oxygen speciesGO:0034614500.017
regulation of nucleotide metabolic processGO:00061402690.017
regulation of purine nucleotide metabolic processGO:19005422640.017
negative regulation of cellular component organizationGO:00511292350.017
anterior posterior axis specificationGO:000994820.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
neuron developmentGO:00486661130.016
chromosome segregationGO:00070591140.016
negative regulation of cell cycleGO:00457861930.016
regulation of protein transportGO:00512232130.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
dna replicationGO:00062601160.016
regulation of bindingGO:00510981110.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
rho protein signal transductionGO:0007266260.016
regulation of transferase activityGO:00513383550.016
memoryGO:000761330.016
cation homeostasisGO:00550801890.016
protein acylationGO:00435431380.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
heart morphogenesisGO:0003007480.016
meiotic chromosome segregationGO:004513240.016
posttranscriptional regulation of gene expressionGO:00106082130.016
regulation of cytoskeleton organizationGO:00514931770.015
mapk cascadeGO:00001652880.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
regulation of anatomical structure morphogenesisGO:00226032860.015
nucleoside monophosphate metabolic processGO:00091231910.015
negative regulation of apoptotic processGO:00430663160.015
regulation of establishment of protein localizationGO:00702012420.015
endosomal transportGO:00161971290.015
developmental process involved in reproductionGO:0003006660.015
single organism carbohydrate metabolic processGO:00447231930.015
regulation of nucleoside metabolic processGO:00091182090.015
small molecule biosynthetic processGO:00442831570.015
regulation of chromosome organizationGO:00330441030.015
positive regulation of transferase activityGO:00513472270.015
guanosine containing compound catabolic processGO:19010692390.015
regulation of intracellular transportGO:00323861950.015
mitochondrial membrane organizationGO:0007006400.015
negative regulation of phosphorus metabolic processGO:00105632670.015
monocarboxylic acid metabolic processGO:00327871850.015
intracellular protein transportGO:00068862700.015
negative regulation of cellular amine metabolic processGO:003323930.015
regulation of protein kinase activityGO:00458592890.015
positive regulation of cellular component biogenesisGO:00440891580.014
organelle fusionGO:0048284360.014
proteasomal protein catabolic processGO:00104981760.014
protein modification by small protein conjugationGO:00324463420.014
regulation of protein maturationGO:19033171500.014
hindbrain developmentGO:003090230.014
spermatid developmentGO:000728640.014
regulation of cellular component movementGO:00512703340.014
regulation of purine nucleotide catabolic processGO:00331212050.014
regulation of mapk cascadeGO:00434082620.014
endomembrane system organizationGO:00102561960.014
cellular protein complex assemblyGO:00436231880.014
response to radiationGO:00093141510.014
negative regulation of cell differentiationGO:00455961710.014
glial cell migrationGO:000834740.014
endocytosisGO:00068971590.014
mitotic cell cycleGO:00002783260.014
spermatid differentiationGO:004851540.014
regulation of nucleotide catabolic processGO:00308112050.014
secretion by cellGO:00329402260.014
compound eye developmentGO:004874910.014
negative regulation of cell deathGO:00605483450.014
defense responseGO:00069523150.014
metal ion transportGO:00300012720.014
innate immune responseGO:00450871780.014
cellular cation homeostasisGO:00300031630.014
secretionGO:00469032540.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
negative regulation of protein modification processGO:00314002000.014
response to other organismGO:00517072610.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
reactive nitrogen species metabolic processGO:200105730.013
sensory perception of painGO:001923340.013
reactive oxygen species metabolic processGO:0072593750.013
reproductionGO:0000003630.013
protein localization to membraneGO:00726571600.013
organ morphogenesisGO:00098871470.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of cytokine productionGO:00018172320.013
chemical homeostasisGO:00488783060.013
ion homeostasisGO:00508012300.013
organonitrogen compound biosynthetic processGO:19015662000.013
organic acid biosynthetic processGO:0016053970.013
negative regulation of protein processingGO:00109551420.013
negative regulation of transportGO:00510511760.013
associative learningGO:000830610.013
protein oligomerizationGO:00512591730.013
heart contractionGO:0060047620.013
response to cytokineGO:00340972320.013
maintenance of locationGO:00512351120.013
positive regulation of protein transportGO:00512221350.013
protein acetylationGO:00064731160.013
protein ubiquitinationGO:00165673140.013
chromatin modificationGO:00165682980.013
somatic muscle developmentGO:000752510.013
macromolecular complex disassemblyGO:0032984600.013
positive regulation of proteolysisGO:00458621420.013
reciprocal meiotic recombinationGO:000713140.013
regulation of protein processingGO:00706131500.013
positive regulation of purine nucleotide catabolic processGO:00331231850.012
negative regulation of intracellular signal transductionGO:19025321830.012
cellular metal ion homeostasisGO:00068751460.012
regulation of secretionGO:00510461940.012
carboxylic acid biosynthetic processGO:0046394970.012
peptidyl lysine modificationGO:00182051440.012
pattern specification processGO:0007389430.012
regenerationGO:003109940.012
regulation of kinase activityGO:00435493140.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of cell migrationGO:00303342890.012
positive regulation of protein catabolic processGO:0045732750.012
heart processGO:0003015620.012
reactive oxygen species biosynthetic processGO:190340940.012
regulation of membrane potentialGO:0042391950.012
response to reactive oxygen speciesGO:0000302610.012
anatomical structure homeostasisGO:00602491000.012
cell divisionGO:00513011680.012
negative regulation of cell proliferationGO:00082852280.012
nucleoside monophosphate catabolic processGO:00091251590.012
positive regulation of nucleoside metabolic processGO:00459791860.012
muscle tissue developmentGO:0060537620.012
protein autophosphorylationGO:00467771230.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
regulation of multi organism processGO:00439001570.012
macromolecule methylationGO:0043414970.012
cellular ion homeostasisGO:00068731680.012
regulation of secretion by cellGO:19035301770.012
organelle localizationGO:0051640840.012
protein methylationGO:0006479740.012
regulation of locomotionGO:00400123290.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
positive regulation of immune system processGO:00026842830.012
photoreceptor cell differentiationGO:004653020.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
regulation of cytoplasmic transportGO:19036491490.012
positive regulation of synaptic transmissionGO:005080640.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
positive regulation of organelle organizationGO:00106381950.012
double strand break repairGO:00063021010.012
negative regulation of cytoskeleton organizationGO:0051494450.011
gtp metabolic processGO:00460392390.011
cell cycle phase transitionGO:00447701730.011
guanosine containing compound metabolic processGO:19010682440.011
regulation of intracellular protein transportGO:00331571230.011
positive regulation of nucleotide metabolic processGO:00459812300.011
regulation of cellular protein catabolic processGO:1903362960.011
embryo developmentGO:00097901230.011
negative regulation of cell cycle processGO:00109481210.011
regulation of cell motilityGO:20001452990.011
regulation of protein complex assemblyGO:00432541470.011
nitrogen compound transportGO:00717051910.011
neurogenesisGO:00220081690.011
immune responseGO:00069553070.011
autophagyGO:0006914880.011
motor neuron axon guidanceGO:000804520.011
methylationGO:00322591060.011
morphogenesis of embryonic epitheliumGO:001633140.011
positive regulation of protein kinase activityGO:00458601900.011
cellular response to cytokine stimulusGO:00713451810.011
positive regulation of kinase activityGO:00336742040.011
nucleocytoplasmic transportGO:00069131760.011
nerve developmentGO:002167540.011
regulation of immune responseGO:00507762010.011
phospholipid metabolic processGO:0006644990.011
negative regulation of hydrolase activityGO:00513461820.011
regulation of protein stabilityGO:0031647870.011
long term memoryGO:000761620.011
cell growthGO:00160491600.011
nuclear transportGO:00511691790.011
negative regulation of programmed cell deathGO:00430693210.011
cellular chemical homeostasisGO:00550821800.011
biological adhesionGO:00226103310.011
regulation of protein serine threonine kinase activityGO:00719001790.011
response to uvGO:0009411730.011
rna interferenceGO:001624640.011
cytokine productionGO:00018162470.011
negative regulation of phosphorylationGO:00423261740.011
positive regulation of protein phosphorylationGO:00019343130.011
positive regulation of nucleotide catabolic processGO:00308131850.011
regulation of cell projection organizationGO:00313441070.011
cardiac muscle cell contractionGO:008600340.011
heart developmentGO:0007507950.011
regulation of protein bindingGO:0043393660.011
positive regulation of gtp catabolic processGO:00331261660.011
head developmentGO:00603221080.010
response to fungusGO:000962040.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
regulation of cell morphogenesisGO:00226041530.010
reproductive system developmentGO:0061458560.010
oxidation reduction processGO:00551143960.010
pharynx developmentGO:006046510.010
negative regulation of protein maturationGO:19033181420.010
cellular response to endogenous stimulusGO:00714953360.010
regulation of synaptic plasticityGO:004816730.010
inorganic ion transmembrane transportGO:00986602310.010
regulation of dna metabolic processGO:00510521530.010
atp catabolic processGO:00062001570.010
cellular amide metabolic processGO:0043603690.010
response to axon injuryGO:004867810.010
regulation of hormone levelsGO:00108171250.010
protein modification by small protein removalGO:0070646920.010
establishment of protein localization to organelleGO:00725941720.010
neuron remodelingGO:001632220.010
dna dependent dna replicationGO:0006261440.010
hemopoiesisGO:00300971800.010
negative regulation of kinase activityGO:00336731060.010
peptidyl lysine acetylationGO:00183941010.010
stress activated mapk cascadeGO:0051403930.010
regulation of defense responseGO:00313471540.010
positive regulation of cell cycleGO:00457871400.010
negative regulation of multicellular organismal processGO:00512413170.010
internal protein amino acid acetylationGO:00064751010.010
response to woundingGO:00096111680.010
mrna metabolic processGO:00160711750.010
establishment of protein localization to membraneGO:00901501210.010
gtp catabolic processGO:00061842370.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.010
positive regulation of cell cycle processGO:00900681060.010
melanin metabolic processGO:000658210.010

HDAC8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.032
nervous system diseaseDOID:8634310.029
sensory system diseaseDOID:00501552030.029
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.026
organ system cancerDOID:00506861640.026
central nervous system diseaseDOID:3311860.025
eye and adnexa diseaseDOID:14921500.020
musculoskeletal system diseaseDOID:172230.019
inherited metabolic disorderDOID:6552420.017
eye diseaseDOID:56141490.016
retinal diseaseDOID:56791180.015
neurodegenerative diseaseDOID:12891020.014
retinal degenerationDOID:8466890.013
immune system diseaseDOID:29141550.013
connective tissue diseaseDOID:651090.012
brain diseaseDOID:936730.011
bone diseaseDOID:0080001880.011
disease of mental healthDOID:150700.011
muscle tissue diseaseDOID:661130.011
muscular diseaseDOID:00800001140.011
cornelia de lange syndromeDOID:1172550.001