Homo sapiens

93 known processes

CDK12

cyclin-dependent kinase 12

(Aliases: CRKR,CRKRS,hCDK12,CRK7,KIAA0904)

CDK12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
determination of adult lifespanGO:000834020.118
vesicle mediated transportGO:00161923710.115
Worm Fly
rna processingGO:00063962550.101
Rat
regulation of anatomical structure morphogenesisGO:00226032860.096
organic hydroxy compound metabolic processGO:19016151470.088
post embryonic developmentGO:000979120.085
Worm
positive regulation of mapk cascadeGO:00434101900.082
Fly
androgen biosynthetic processGO:000670230.080
immune system developmentGO:00025201950.074
Human
erk1 and erk2 cascadeGO:00703711040.073
Fly
activation of store operated calcium channel activityGO:003223740.067
actin filament based processGO:00300292240.062
positive regulation of cellular component organizationGO:00511303760.060
ion transmembrane transportGO:00342203380.059
cellular divalent inorganic cation homeostasisGO:00725031280.056
regulation of transferase activityGO:00513383550.056
organophosphate catabolic processGO:00464344300.054
multicellular organismal agingGO:001025930.053
regulation of ras protein signal transductionGO:00465781550.052
Fly
protein modification by small protein conjugationGO:00324463420.052
histone modificationGO:00165702510.051
signal transduction by phosphorylationGO:00230142970.051
regulation of cell cycleGO:00517263930.051
cellular amino acid metabolic processGO:00065201160.051
metal ion transportGO:00300012720.050
cell morphogenesisGO:00009022960.049
small gtpase mediated signal transductionGO:0007264780.049
Fly
protein ubiquitinationGO:00165673140.048
lens development in camera type eyeGO:000208820.048
purine nucleoside triphosphate metabolic processGO:00091444120.048
cellular component morphogenesisGO:00329893140.048
cellular response to histamineGO:007142030.047
cellular macromolecule catabolic processGO:00442653800.046
cellular amine metabolic processGO:0044106410.046
chromatin modificationGO:00165682980.045
regulation of cellular amine metabolic processGO:0033238110.045
positive regulation of developmental processGO:00510943140.044
positive regulation of immune system processGO:00026842830.044
negative regulation of hydrolase activityGO:00513461820.044
ras protein signal transductionGO:0007265730.044
Fly
negative regulation of programmed cell deathGO:00430693210.042
system processGO:00030083490.042
calcium ion homeostasisGO:00550741220.041
compound eye developmentGO:004874910.040
metal ion homeostasisGO:00550651690.040
phosphorylation of rna polymerase ii c terminal domainGO:007081630.039
mitotic cell cycleGO:00002783260.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
positive regulation of transportGO:00510503360.038
regulation of protein localizationGO:00328802960.037
nervous system developmentGO:00073992930.037
Fly
regulation of cellular amino acid metabolic processGO:000652160.037
actin cytoskeleton organizationGO:00300362070.036
immune responseGO:00069553070.036
regulation of proteolysisGO:00301622930.036
cardiovascular system developmentGO:00723582620.036
regulation of purine nucleotide metabolic processGO:19005422640.036
cytoplasmic transportGO:00164823790.036
secretionGO:00469032540.035
positive regulation of cellular catabolic processGO:00313312840.035
regulation of mapk cascadeGO:00434082620.035
reproductive processGO:00224141060.035
Worm
cellular cation homeostasisGO:00300031630.034
embryo developmentGO:00097901230.033
Worm
blood vessel developmentGO:00015681720.033
mitotic cell cycle phase transitionGO:00447721620.032
protein autophosphorylationGO:00467771230.032
locomotory behaviorGO:000762610.032
regulation of map kinase activityGO:00434051080.032
response to organic cyclic compoundGO:00140702040.032
ion homeostasisGO:00508012300.031
membrane organizationGO:00610242920.031
cellular response to growth factor stimulusGO:00713631970.031
cation transportGO:00068123310.030
innate immune responseGO:00450871780.030
intracellular protein transportGO:00068862700.030
amine metabolic processGO:0009308440.030
regulation of cell morphogenesisGO:00226041530.030
regulation of kinase activityGO:00435493140.030
regulation of protein kinase activityGO:00458592890.029
negative regulation of apoptotic processGO:00430663160.029
purine ribonucleoside catabolic processGO:00461303980.029
cellular response to dna damage stimulusGO:00069743790.029
hemopoiesisGO:00300971800.028
Human
growthGO:00400072020.027
ncrna metabolic processGO:00346601080.027
regulation of cell cycle processGO:00105642660.027
cellular protein catabolic processGO:00442572610.027
regulation of cellular protein catabolic processGO:1903362960.026
cellular macromolecular complex assemblyGO:00346223240.026
cation homeostasisGO:00550801890.026
glycosyl compound catabolic processGO:19016584130.026
regulation of actin filament lengthGO:0030832560.026
guanosine containing compound metabolic processGO:19010682440.026
cytokinesisGO:0000910960.025
protein acylationGO:00435431380.025
segmentationGO:003528240.025
methylationGO:00322591060.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
chromatin organizationGO:00063253510.025
regulation of response to external stimulusGO:00321012220.025
negative regulation of cell deathGO:00605483450.025
actin mediated cell contractionGO:0070252120.025
positive regulation of phosphorylationGO:00423273940.025
Fly
regulation of nucleotide metabolic processGO:00061402690.025
regulation of histone modificationGO:0031056470.025
purine ribonucleotide catabolic processGO:00091544040.024
positive regulation of cell differentiationGO:00455972110.024
nucleoside phosphate catabolic processGO:19012924120.024
neurogenesisGO:00220081690.024
Fly
lipid biosynthetic processGO:00086101770.024
positive regulation of cell cycle processGO:00900681060.024
nucleotide catabolic processGO:00091664080.024
cation transmembrane transportGO:00986552380.024
chemical homeostasisGO:00488783060.024
protein targetingGO:00066051870.023
regulation of ion transportGO:00432691890.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
cellular response to organic cyclic compoundGO:00714071270.023
calcium ion transportGO:00068161470.023
hematopoietic or lymphoid organ developmentGO:00485341860.023
Human
regulation of intracellular transportGO:00323861950.023
cellular ketone metabolic processGO:0042180800.023
negative regulation of protein metabolic processGO:00512483910.023
mapk cascadeGO:00001652880.023
response to growth factorGO:00708482050.023
positive regulation of cellular amino acid metabolic processGO:004576430.022
purine ribonucleoside metabolic processGO:00461284370.022
inorganic ion transmembrane transportGO:00986602310.022
neurological system processGO:00508771630.022
ubiquitin dependent protein catabolic processGO:00065112060.022
positive regulation of protein import into nucleusGO:0042307460.022
sequestering of metal ionGO:0051238240.022
tripartite regional subdivisionGO:000735120.022
regulation of protein serine threonine kinase activityGO:00719001790.022
positive regulation of organelle organizationGO:00106381950.022
positive regulation of store operated calcium channel activityGO:190134140.022
positive regulation of peroxisome proliferator activated receptor signaling pathwayGO:003536040.022
spermatid differentiationGO:004851540.022
defense responseGO:00069523150.021
maturation of ssu rrnaGO:003049030.021
transmembrane transportGO:00550853990.021
divalent inorganic cation homeostasisGO:00725071360.021
negative regulation of protein modification processGO:00314002000.021
regulation of cytoplasmic transportGO:19036491490.021
regulation of apoptotic signaling pathwayGO:20012331750.021
actin filament based movementGO:0030048170.021
protein localization to organelleGO:00333652800.021
internal protein amino acid acetylationGO:00064751010.021
cellular homeostasisGO:00197251960.021
negative regulation of catalytic activityGO:00430863350.021
g2 m transition of mitotic cell cycleGO:0000086410.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
blood vessel morphogenesisGO:00485141620.020
purine nucleoside catabolic processGO:00061523980.020
anterior posterior axis specificationGO:000994820.020
mitotic cell cycle processGO:19030472860.020
organelle fissionGO:00482851490.020
divalent inorganic cation transportGO:00725111580.020
cell growthGO:00160491600.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
inorganic cation transmembrane transportGO:00986621940.020
regulation of protein modification by small protein conjugation or removalGO:19033201070.020
regulation of proteasomal protein catabolic processGO:0061136870.020
protein catabolic processGO:00301633250.020
neuromuscular junction developmentGO:000752830.020
ribonucleoside catabolic processGO:00424544060.020
regulation of cellular component biogenesisGO:00440872810.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
angiogenesisGO:00015251470.019
peptidyl lysine acetylationGO:00183941010.019
regulation of hormone levelsGO:00108171250.019
purine nucleotide catabolic processGO:00061954050.019
ncrna processingGO:0034470830.019
regulation of metal ion transportGO:00109591200.019
female gamete generationGO:000729220.019
purine containing compound catabolic processGO:00725234110.019
regulation of protein transportGO:00512232130.019
divalent metal ion transportGO:00708381520.019
lung alveolus developmentGO:004828640.019
regulation of cellular ketone metabolic processGO:0010565500.018
nucleoside triphosphate catabolic processGO:00091433940.018
positive regulation of intracellular protein transportGO:0090316760.018
negative regulation of cellular protein metabolic processGO:00322693530.018
regulation of nucleoside metabolic processGO:00091182090.018
lipid metabolic processGO:00066293810.018
positive regulation of cellular amine metabolic processGO:003324070.018
cellular calcium ion homeostasisGO:00068741170.018
organonitrogen compound biosynthetic processGO:19015662000.018
meiosis iGO:000712740.018
regulation of calcium ion transportGO:0051924790.018
regulation of cell projection organizationGO:00313441070.018
negative regulation of cellular amine metabolic processGO:003323930.018
single organism membrane organizationGO:00448022680.018
regulation of cell differentiationGO:00455953930.018
cell cycle phase transitionGO:00447701730.018
rho protein signal transductionGO:0007266260.018
rna catabolic processGO:0006401710.017
organophosphate biosynthetic processGO:00904071630.017
single organism cellular localizationGO:19025803320.017
cellular ion homeostasisGO:00068731680.017
vasculature developmentGO:00019441810.017
positive regulation of nucleotide metabolic processGO:00459812300.017
histone acetylationGO:0016573930.017
regulation of multi organism processGO:00439001570.017
positive regulation of protein transportGO:00512221350.017
negative regulation of phosphorus metabolic processGO:00105632670.017
spermatid developmentGO:000728640.017
response to woundingGO:00096111680.017
negative regulation of phosphate metabolic processGO:00459362670.017
mrna metabolic processGO:00160711750.017
blastoderm segmentationGO:000735020.017
rna interferenceGO:001624640.017
apoptotic signaling pathwayGO:00971902680.017
embryonic eye morphogenesisGO:004804820.017
nucleocytoplasmic transportGO:00069131760.017
axon cargo transportGO:000808820.017
regulation of protein targetingGO:1903533910.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
Fly
internal peptidyl lysine acetylationGO:0018393970.017
maintenance of locationGO:00512351120.017
gtp metabolic processGO:00460392390.017
regulation of cell shapeGO:0008360480.016
positive regulation of chromosome organizationGO:2001252410.016
guanosine containing compound catabolic processGO:19010692390.016
positive regulation of cell cycleGO:00457871400.016
positive regulation of erk1 and erk2 cascadeGO:0070374750.016
Fly
organelle assemblyGO:00709251760.016
regulation of response to woundingGO:19030341010.016
negative regulation of cellular component organizationGO:00511292350.016
cell divisionGO:00513011680.016
regulation of chromosome organizationGO:00330441030.016
cellular lipid metabolic processGO:00442553030.016
positive regulation of mitotic cell cycleGO:0045931600.016
neuron differentiationGO:00301821380.016
sequestering of calcium ionGO:0051208170.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
protein importGO:00170381300.015
ribonucleotide catabolic processGO:00092614050.015
anterior posterior axis specification embryoGO:000859520.015
cell projection assemblyGO:00300311260.015
gtp catabolic processGO:00061842370.015
carbohydrate metabolic processGO:00059752070.015
myeloid cell differentiationGO:00300991170.015
cellular response to cytokine stimulusGO:00713451810.015
positive regulation of gtp catabolic processGO:00331261660.015
proteasomal protein catabolic processGO:00104981760.015
phospholipid metabolic processGO:0006644990.015
regulation of protein ubiquitinationGO:0031396950.015
positive regulation of catabolic processGO:00098963100.015
nuclear transportGO:00511691790.015
covalent chromatin modificationGO:00165692540.015
regenerationGO:003109940.015
rna splicingGO:00083801310.015
Rat
chromosome segregationGO:00070591140.015
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.015
regulation of defense responseGO:00313471540.014
calcium ion transmembrane transportGO:0070588760.014
regulation of nucleotide catabolic processGO:00308112050.014
regulation of axon guidanceGO:190266730.014
embryonic camera type eye developmentGO:003107620.014
rrna metabolic processGO:0016072400.014
photoreceptor cell differentiationGO:004653020.014
epithelium developmentGO:00604292270.014
cytokine mediated signaling pathwayGO:00192211090.014
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.014
cell projection organizationGO:00300302520.014
cytokine productionGO:00018162470.014
pharynx developmentGO:006046510.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
regulation of protein import into nucleusGO:0042306780.014
regulation of biomineral tissue developmentGO:0070167310.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of protein localization to nucleusGO:1900180850.014
regulation of chromatin organizationGO:1902275560.014
melanin metabolic processGO:000658210.014
regulation of immune responseGO:00507762010.014
carbohydrate derivative biosynthetic processGO:19011372070.014
leukocyte differentiationGO:0002521980.014
regulation of homeostatic processGO:00328441210.013
cellular hormone metabolic processGO:0034754410.013
cellular metal ion homeostasisGO:00068751460.013
actin filament organizationGO:00070151280.013
regulation of cellular component sizeGO:0032535820.013
hindlimb morphogenesisGO:003513720.013
oogenesisGO:004847720.013
reproductionGO:0000003630.013
Worm
regulation of meiotic cell cycleGO:005144540.013
regulation of protein complex assemblyGO:00432541470.013
cellular response to endogenous stimulusGO:00714953360.013
positive regulation of apoptotic processGO:00430652460.013
positive regulation of cell proliferationGO:00082843010.013
regulation of protein maturationGO:19033171500.013
regulation of vasculature developmentGO:1901342970.013
embryonic morphogenesisGO:0048598850.013
positive regulation of protein complex assemblyGO:0031334860.013
regulation of bindingGO:00510981110.013
response to cytokineGO:00340972320.013
immune effector processGO:00022521590.013
regulation of anatomical structure sizeGO:00900661010.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
regulation of dna metabolic processGO:00510521530.013
cardiac muscle cell contractionGO:008600340.013
generation of neuronsGO:00486991520.013
nuclear importGO:00511701060.013
intracellular receptor signaling pathwayGO:00305221040.013
regulation of purine nucleotide catabolic processGO:00331212050.013
positive regulation of intracellular transportGO:00323881040.013
hormone metabolic processGO:0042445610.013
regulation of establishment of protein localizationGO:00702012420.013
single organism nuclear importGO:19025931040.012
memoryGO:000761330.012
regulation of cellular response to stressGO:00801352440.012
embryonic camera type eye morphogenesisGO:004859620.012
negative regulation of protein processingGO:00109551420.012
modification dependent protein catabolic processGO:00199412090.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
protein oligomerizationGO:00512591730.012
nucleoside catabolic processGO:00091644080.012
negative regulation of protein maturationGO:19033181420.012
response to abiotic stimulusGO:00096283360.012
regulation of nucleocytoplasmic transportGO:0046822980.012
protein targeting to nucleusGO:00447441040.012
posttranscriptional regulation of gene expressionGO:00106082130.012
oocyte developmentGO:004859910.012
regulation of response to oxidative stressGO:1902882260.012
cellular response to ammonium ionGO:007124240.012
response to nitrogen compoundGO:19016981840.012
regulation of cellular component movementGO:00512703340.012
positive regulation of cytokine productionGO:00018191670.012
branch elongation of an epitheliumGO:006060230.012
regulation of mitotic cell cycleGO:00073461890.012
protein dna complex subunit organizationGO:0071824800.012
head developmentGO:00603221080.012
single organism reproductive processGO:0044702980.012
Worm
macromolecule methylationGO:0043414970.012
nerve developmentGO:002167540.012
regulation of protein catabolic processGO:00421761550.012
regulation of leukocyte differentiationGO:1902105610.012
myeloid leukocyte differentiationGO:0002573600.012
response to histamineGO:003477660.012
protein glycosylationGO:0006486620.012
positive regulation of nucleotide catabolic processGO:00308131850.011
positive regulation of defense responseGO:0031349870.011
negative regulation of cell proliferationGO:00082852280.011
developmental growthGO:0048589480.011
central nervous system developmentGO:00074171230.011
visual behaviorGO:000763220.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
cellular protein complex assemblyGO:00436231880.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
somitogenesisGO:000175620.011
sensory perception of mechanical stimulusGO:0050954370.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of dephosphorylationGO:0035303960.011
dephosphorylationGO:00163112090.011
regulation of cytoskeleton organizationGO:00514931770.011
blastocyst developmentGO:000182430.011
vitamin d receptor signaling pathwayGO:007056140.011
regulation of ion transmembrane transporter activityGO:0032412720.011
regulation of actin filament based processGO:00329701410.011
protein processingGO:00164852260.011
negative regulation of phosphatase activityGO:0010923610.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
regulation of transporter activityGO:0032409820.011
regulation of actin cytoskeleton organizationGO:00329561160.011
detection of chemical stimulusGO:0009593550.011
intracellular steroid hormone receptor signaling pathwayGO:0030518610.011
regulation of ion transmembrane transportGO:00347651320.011
protein import into nucleusGO:00066061040.011
actin polymerization or depolymerizationGO:0008154560.011
glycerolipid metabolic processGO:00464861070.011
regulation of intracellular protein transportGO:00331571230.011
phagocytosisGO:0006909420.011
Fly
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
positive regulation of nucleocytoplasmic transportGO:0046824540.010
adult locomotory behaviorGO:000834410.010
cellular modified amino acid metabolic processGO:0006575640.010
regulation of meiosisGO:004002030.010
endomembrane system organizationGO:00102561960.010
sensory perceptionGO:00076001030.010
tissue morphogenesisGO:0048729960.010
single organism carbohydrate metabolic processGO:00447231930.010
histone h3 acetylationGO:0043966450.010
positive regulation of immune responseGO:00507781590.010
nuclear divisionGO:00002801280.010
regulation of protein polymerizationGO:0032271630.010
negative regulation of intracellular signal transductionGO:19025321830.010

CDK12 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.054
cancerDOID:1621670.041
organ system cancerDOID:00506861640.037
central nervous system diseaseDOID:3311860.033
nervous system diseaseDOID:8634310.033
sensory system diseaseDOID:00501552030.025
auditory system diseaseDOID:2742530.025
neurodegenerative diseaseDOID:12891020.024
endocrine gland cancerDOID:170260.021
nonsyndromic deafnessDOID:0050563500.020
musculoskeletal system diseaseDOID:172230.020
connective tissue diseaseDOID:651090.014
cardiovascular system diseaseDOID:12871060.014
bone diseaseDOID:0080001880.013
physical disorderDOID:0080015410.012
congenital nervous system abnormalityDOID:2490210.012
eye diseaseDOID:56141490.011
eye and adnexa diseaseDOID:14921500.011
immune system diseaseDOID:29141550.011
hematopoietic system diseaseDOID:741000.011
muscle tissue diseaseDOID:661130.010
muscular diseaseDOID:00800001140.010
myopathyDOID:4231040.010