Homo sapiens

0 known processes

PKDREJ

polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)

PKDREJ biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amino acid metabolic processGO:000652160.157
cellular ketone metabolic processGO:0042180800.150
cellular amine metabolic processGO:0044106410.138
transmembrane transportGO:00550853990.128
regulation of cellular amine metabolic processGO:0033238110.127
system processGO:00030083490.123
cellular amino acid metabolic processGO:00065201160.122
cation transportGO:00068123310.120
regulation of cellular ketone metabolic processGO:0010565500.120
chemical homeostasisGO:00488783060.112
amine metabolic processGO:0009308440.111
ion homeostasisGO:00508012300.088
cation transmembrane transportGO:00986552380.086
inorganic ion transmembrane transportGO:00986602310.085
cellular response to endogenous stimulusGO:00714953360.084
positive regulation of cellular amino acid metabolic processGO:004576430.082
negative regulation of multicellular organismal processGO:00512413170.082
ion transmembrane transportGO:00342203380.082
positive regulation of developmental processGO:00510943140.079
metal ion homeostasisGO:00550651690.079
negative regulation of transportGO:00510511760.072
regulation of transferase activityGO:00513383550.068
metal ion transportGO:00300012720.068
post embryonic developmentGO:000979120.067
cellular chemical homeostasisGO:00550821800.067
positive regulation of cellular amine metabolic processGO:003324070.065
regulation of locomotionGO:00400123290.064
cellular homeostasisGO:00197251960.061
cellular ion homeostasisGO:00068731680.058
negative regulation of developmental processGO:00510932470.057
regulation of cell differentiationGO:00455953930.055
organ morphogenesisGO:00098871470.055
cation homeostasisGO:00550801890.054
anion transportGO:00068201610.054
response to organic cyclic compoundGO:00140702040.051
nervous system developmentGO:00073992930.051
positive regulation of cell proliferationGO:00082843010.051
positive regulation of transportGO:00510503360.051
cytoplasmic transportGO:00164823790.050
locomotory behaviorGO:000762610.050
lipid metabolic processGO:00066293810.050
cellular divalent inorganic cation homeostasisGO:00725031280.050
defense responseGO:00069523150.049
regulation of cellular component movementGO:00512703340.049
negative regulation of cellular protein metabolic processGO:00322693530.048
single organism cellular localizationGO:19025803320.048
negative regulation of protein metabolic processGO:00512483910.048
response to cytokineGO:00340972320.046
immune responseGO:00069553070.045
cellular response to oxygen containing compoundGO:19017012760.045
neurological system processGO:00508771630.045
cellular response to cytokine stimulusGO:00713451810.045
g protein coupled receptor signaling pathwayGO:00071862070.045
positive regulation of phosphorylationGO:00423273940.044
response to oxygen containing compoundGO:19017003690.044
enzyme linked receptor protein signaling pathwayGO:00071673030.043
single organism membrane organizationGO:00448022680.043
cell developmentGO:00484683280.043
secretionGO:00469032540.042
purine ribonucleoside metabolic processGO:00461284370.042
divalent inorganic cation homeostasisGO:00725071360.042
signal transduction by phosphorylationGO:00230142970.042
membrane organizationGO:00610242920.041
response to hormoneGO:00097251750.041
response to abiotic stimulusGO:00096283360.041
segmentationGO:003528240.041
response to biotic stimulusGO:00096072760.040
cellular cation homeostasisGO:00300031630.040
organophosphate catabolic processGO:00464344300.040
cytokine productionGO:00018162470.040
regulation of mapk cascadeGO:00434082620.040
inorganic cation transmembrane transportGO:00986621940.040
calcium ion homeostasisGO:00550741220.039
cellular macromolecule catabolic processGO:00442653800.039
positive regulation of transferase activityGO:00513472270.039
cellular metal ion homeostasisGO:00068751460.038
regulation of ion transportGO:00432691890.038
cellular calcium ion homeostasisGO:00068741170.037
response to lipidGO:00339932060.037
oxidation reduction processGO:00551143960.037
negative regulation of phosphate metabolic processGO:00459362670.036
positive regulation of hydrolase activityGO:00513453310.036
regulation of transmembrane transportGO:00347621390.036
regulation of ion transmembrane transportGO:00347651320.036
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.035
intracellular protein transportGO:00068862700.035
cellular component morphogenesisGO:00329893140.035
positive regulation of protein phosphorylationGO:00019343130.035
ribonucleoside catabolic processGO:00424544060.035
mapk cascadeGO:00001652880.035
positive regulation of immune system processGO:00026842830.035
regulation of cell cycle processGO:00105642660.035
negative regulation of cell deathGO:00605483450.035
negative regulation of cell proliferationGO:00082852280.034
negative regulation of cellular component organizationGO:00511292350.034
negative regulation of catalytic activityGO:00430863350.034
regulation of cell motilityGO:20001452990.033
protein maturationGO:00516042330.033
actin filament based processGO:00300292240.033
regulation of cell migrationGO:00303342890.033
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.033
positive regulation of cellular component organizationGO:00511303760.033
adult locomotory behaviorGO:000834410.032
regulation of response to external stimulusGO:00321012220.032
epithelium developmentGO:00604292270.031
regulation of anatomical structure morphogenesisGO:00226032860.031
memoryGO:000761330.031
monovalent inorganic cation transportGO:00156721280.031
positive regulation of cell deathGO:00109422630.031
negative regulation of cell differentiationGO:00455961710.031
protein modification by small protein conjugationGO:00324463420.031
positive regulation of cell differentiationGO:00455972110.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
regulation of large conductance calcium activated potassium channel activityGO:190260620.031
anatomical structure formation involved in morphogenesisGO:00486462840.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
multicellular organismal agingGO:001025930.031
negative regulation of phosphorus metabolic processGO:00105632670.031
cell morphogenesisGO:00009022960.030
nucleoside catabolic processGO:00091644080.030
cardiac muscle cell contractionGO:008600340.030
blood circulationGO:00080151130.030
epidermis morphogenesisGO:004873030.030
circulatory system developmentGO:00723592620.030
protein localization to organelleGO:00333652800.030
ribonucleotide catabolic processGO:00092614050.030
purine ribonucleotide catabolic processGO:00091544040.030
nucleoside phosphate catabolic processGO:19012924120.030
protein catabolic processGO:00301633250.030
associative learningGO:000830610.030
negative regulation of protein modification processGO:00314002000.030
determination of adult lifespanGO:000834020.029
negative regulation of programmed cell deathGO:00430693210.029
oogenesisGO:004847720.029
positive regulation of apoptotic processGO:00430652460.029
cell cell signalingGO:00072671550.029
positive regulation of programmed cell deathGO:00430682490.029
response to external biotic stimulusGO:00432072610.029
regulation of kinase activityGO:00435493140.029
regulation of protein kinase activityGO:00458592890.029
organonitrogen compound biosynthetic processGO:19015662000.029
purine ribonucleoside catabolic processGO:00461303980.029
regulation of cell cycleGO:00517263930.028
small gtpase mediated signal transductionGO:0007264780.028
female gamete generationGO:000729220.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
purine nucleotide catabolic processGO:00061954050.028
negative regulation of cellular amine metabolic processGO:003323930.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
chromatin organizationGO:00063253510.028
purine containing compound catabolic processGO:00725234110.028
immune system developmentGO:00025201950.027
reactive oxygen species metabolic processGO:0072593750.027
glycosyl compound catabolic processGO:19016584130.027
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.027
regulation of purine nucleotide metabolic processGO:19005422640.027
protein processingGO:00164852260.027
regulation of secretionGO:00510461940.027
endomembrane system organizationGO:00102561960.027
regulation of establishment of protein localizationGO:00702012420.027
cellular lipid metabolic processGO:00442553030.027
regulation of protein localizationGO:00328802960.027
cellular response to hormone stimulusGO:00328701250.027
positive regulation of cell cycleGO:00457871400.026
epithelial cell differentiationGO:00308551410.026
positive regulation of locomotionGO:00400171860.026
nucleoside triphosphate metabolic processGO:00091414220.026
ras protein signal transductionGO:0007265730.026
regulation of cellular component biogenesisGO:00440872810.026
cellular protein catabolic processGO:00442572610.026
carbohydrate metabolic processGO:00059752070.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
purine nucleoside catabolic processGO:00061523980.025
regulation of protein transportGO:00512232130.025
positive regulation of mapk cascadeGO:00434101900.025
regulation of proteolysisGO:00301622930.025
regulation of membrane potentialGO:0042391950.025
regulation of cytokine productionGO:00018172320.025
epithelial cell proliferationGO:00506731280.025
regulation of body fluid levelsGO:0050878990.025
cytosolic calcium ion homeostasisGO:0051480890.024
protein ubiquitinationGO:00165673140.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
vesicle mediated transportGO:00161923710.024
regulation of ion transmembrane transporter activityGO:0032412720.024
cellular response to dna damage stimulusGO:00069743790.024
chromatin modificationGO:00165682980.024
hindbrain developmentGO:003090230.024
regulation of transporter activityGO:0032409820.024
cellular response to growth factor stimulusGO:00713631970.024
response to nitrogen compoundGO:19016981840.024
hemopoiesisGO:00300971800.024
secretion by cellGO:00329402260.024
reactive oxygen species biosynthetic processGO:190340940.024
cellular response to organonitrogen compoundGO:00714171240.024
positive regulation of cytosolic calcium ion concentrationGO:0007204820.024
innate immune responseGO:00450871780.023
muscle contractionGO:0006936730.023
nucleotide catabolic processGO:00091664080.023
regulation of secretion by cellGO:19035301770.023
biological adhesionGO:00226103310.023
nitrogen compound transportGO:00717051910.023
growthGO:00400072020.023
matingGO:000761810.023
regulation of sequence specific dna binding transcription factor activityGO:00510902110.023
regulation of nucleotide metabolic processGO:00061402690.023
organ formationGO:004864530.023
tube developmentGO:00352951250.023
epithelial cell migrationGO:00106311190.023
regulation of nucleoside metabolic processGO:00091182090.023
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
cell projection organizationGO:00300302520.023
cell activationGO:00017752130.023
positive regulation of cellular catabolic processGO:00313312840.023
cardiovascular system developmentGO:00723582620.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
protein targetingGO:00066051870.022
response to other organismGO:00517072610.022
hematopoietic or lymphoid organ developmentGO:00485341860.022
carbohydrate derivative biosynthetic processGO:19011372070.022
maintenance of locationGO:00512351120.022
regulation of cellular response to stressGO:00801352440.022
actin cytoskeleton organizationGO:00300362070.022
positive regulation of catabolic processGO:00098963100.022
regulation of response to woundingGO:19030341010.022
neuromuscular junction developmentGO:000752830.022
nucleoside triphosphate catabolic processGO:00091433940.021
taxisGO:00423301570.021
peptidyl tyrosine modificationGO:00182121700.021
neuron fate commitmentGO:004866320.021
regenerationGO:003109940.021
divalent inorganic cation transportGO:00725111580.021
blood vessel developmentGO:00015681720.021
negative regulation of apoptotic processGO:00430663160.021
glycine importGO:003623310.021
regulation of leukocyte activationGO:00026941150.021
protein acylationGO:00435431380.021
protein oligomerizationGO:00512591730.021
leukocyte activationGO:00453211640.021
posttranscriptional regulation of gene expressionGO:00106082130.020
wnt signaling pathwayGO:00160551560.020
organic hydroxy compound metabolic processGO:19016151470.020
calcium ion transportGO:00068161470.020
positive regulation of nucleotide metabolic processGO:00459812300.020
organophosphate biosynthetic processGO:00904071630.020
regulation of reactive oxygen species metabolic processGO:2000377410.020
reactive nitrogen species metabolic processGO:200105730.020
establishment of protein localization to membraneGO:00901501210.020
regulation of cell activationGO:00508651250.020
regulation of cell developmentGO:00602841610.020
covalent chromatin modificationGO:00165692540.020
mitotic cell cycleGO:00002783260.020
cellular macromolecular complex assemblyGO:00346223240.020
regulation of protein complex assemblyGO:00432541470.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of cell migrationGO:00303351720.020
organic anion transportGO:00157111030.019
protein localization to membraneGO:00726571600.019
regulation of intracellular transportGO:00323861950.019
regulation of cytoskeleton organizationGO:00514931770.019
epithelium migrationGO:00901321190.019
vasculature developmentGO:00019441810.019
muscle system processGO:0003012810.019
negative regulation of locomotionGO:00400131180.019
central nervous system developmentGO:00074171230.019
carboxylic acid transportGO:0046942630.019
protein acetylationGO:00064731160.019
divalent metal ion transportGO:00708381520.019
brain developmentGO:0007420970.019
regulation of reactive oxygen species biosynthetic processGO:190342630.019
positive regulation of cell cycle processGO:00900681060.019
positive regulation of kinase activityGO:00336742040.019
circulatory system processGO:00030131130.019
regulation of metal ion transportGO:00109591200.019
positive regulation of ion transportGO:0043270870.019
histone modificationGO:00165702510.018
regulation of cell divisionGO:00513021160.018
striated muscle contractionGO:0006941520.018
sensory perceptionGO:00076001030.018
rhythmic behaviorGO:000762220.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
second messenger mediated signalingGO:0019932780.018
sodium ion transmembrane transportGO:0035725590.018
regulation of transmembrane transporter activityGO:0022898740.018
negative regulation of protein phosphorylationGO:00019331400.018
viral processGO:00160321460.018
cellular response to nitrogen compoundGO:19016991440.018
cell adhesionGO:00071553250.018
anion transmembrane transportGO:0098656760.018
blastoderm segmentationGO:000735020.018
establishment of protein localization to organelleGO:00725941720.018
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of cellular component movementGO:00512721810.018
nucleocytoplasmic transportGO:00069131760.018
sequestering of metal ionGO:0051238240.018
cellular response to organic cyclic compoundGO:00714071270.018
regulation of dna metabolic processGO:00510521530.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
ameboidal type cell migrationGO:00016671350.018
response to decreased oxygen levelsGO:0036293960.018
cell growthGO:00160491600.018
nucleoside phosphate biosynthetic processGO:19012931090.018
positive regulation of cell motilityGO:20001471770.018
nerve developmentGO:002167540.017
behaviorGO:00076101120.017
circadian behaviorGO:004851220.017
response to organonitrogen compoundGO:00102431560.017
negative regulation of phosphorylationGO:00423261740.017
response to woundingGO:00096111680.017
plasma membrane organizationGO:00070091150.017
neurogenesisGO:00220081690.017
positive regulation of protein kinase activityGO:00458601900.017
sequestering of calcium ionGO:0051208170.017
regulation of epithelial cell proliferationGO:00506781130.017
action potentialGO:0001508340.017
response to growth factorGO:00708482050.017
dephosphorylationGO:00163112090.017
canonical wnt signaling pathwayGO:00600701160.017
detection of stimulusGO:0051606850.017
regulation of immune responseGO:00507762010.017
guanosine containing compound metabolic processGO:19010682440.017
regulation of cytoplasmic transportGO:19036491490.017
monocarboxylic acid metabolic processGO:00327871850.017
tissue migrationGO:00901301190.017
regulation of protein serine threonine kinase activityGO:00719001790.017
generation of neuronsGO:00486991520.016
regulation of protein maturationGO:19033171500.016
organic acid transportGO:0015849650.016
cytokine mediated signaling pathwayGO:00192211090.016
positive regulation of nucleotide catabolic processGO:00308131850.016
nuclear transportGO:00511691790.016
negative regulation of cytosolic calcium ion concentrationGO:005148110.016
single organism reproductive processGO:0044702980.016
positive regulation of nucleoside metabolic processGO:00459791860.016
actin filament based movementGO:0030048170.016
response to oxygen levelsGO:00704821000.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
protein localization to nucleusGO:00345041360.016
multi organism cellular processGO:00447641560.016
cell fate determinationGO:000170930.016
negative regulation of cell cycleGO:00457861930.016
cell morphogenesis involved in differentiationGO:00009041440.016
intracellular receptor signaling pathwayGO:00305221040.016
cell divisionGO:00513011680.016
limbic system developmentGO:002176130.016
mitotic cell cycle processGO:19030472860.016
spermatid differentiationGO:004851540.016
actin mediated cell contractionGO:0070252120.016
interspecies interaction between organismsGO:00444191560.016
regulation of peptidase activityGO:00525471800.016
apoptotic signaling pathwayGO:00971902680.016
morphogenesis of embryonic epitheliumGO:001633140.016
i kappab kinase nf kappab signalingGO:00072491660.016
sex determinationGO:000753030.016
rho protein signal transductionGO:0007266260.016
angiogenesisGO:00015251470.015
regulation of growthGO:00400081650.015
neuron differentiationGO:00301821380.015
extraocular skeletal muscle developmentGO:000207410.015
negative regulation of immune system processGO:00026831360.015
positive regulation of cell divisionGO:0051781590.015
regulation of homeostatic processGO:00328441210.015
regulation of protein processingGO:00706131500.015
guanosine containing compound catabolic processGO:19010692390.015
regulation of multi organism processGO:00439001570.015
hair follicle morphogenesisGO:003106920.015
regulation of purine nucleotide catabolic processGO:00331212050.015
nucleotide biosynthetic processGO:00091651090.015
gtp metabolic processGO:00460392390.015
regulation of cell morphogenesisGO:00226041530.015
cell cycle phase transitionGO:00447701730.015
negative regulation of hydrolase activityGO:00513461820.015
thymus developmentGO:004853830.015
dna repairGO:00062811980.015
anterior posterior axis specificationGO:000994820.015
positive regulation of organelle organizationGO:00106381950.015
regulation of hormone levelsGO:00108171250.015
somatostatin receptor signaling pathwayGO:003816910.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
regulation of synaptic plasticityGO:004816730.015
regulation of lipid metabolic processGO:0019216960.015
sleepGO:003043120.015
oocyte developmentGO:004859910.015
positive regulation of keratinocyte migrationGO:005154940.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of secretion by cellGO:19035321080.015
visual learningGO:000854210.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
metencephalon developmentGO:002203720.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
lipid localizationGO:00108761060.014
blood coagulationGO:0007596760.014
blood vessel morphogenesisGO:00485141620.014
spinal cord developmentGO:002151040.014
negative regulation of protein transportGO:0051224750.014
regulation of protein catabolic processGO:00421761550.014
somatostatin signaling pathwayGO:003817010.014
regulation of actin filament based processGO:00329701410.014
negative regulation of response to external stimulusGO:0032102830.014
somitogenesisGO:000175620.014
potassium ion transportGO:0006813620.014
purine containing compound biosynthetic processGO:0072522880.014
regulation of gtpase activityGO:00430871800.014
mitotic cell cycle phase transitionGO:00447721620.014
positive regulation of intracellular transportGO:00323881040.014
lipid biosynthetic processGO:00086101770.014
wound healingGO:00420601150.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
regulation of erk1 and erk2 cascadeGO:0070372990.014
organelle assemblyGO:00709251760.014
protein importGO:00170381300.014
somatic stem cell maintenanceGO:003501940.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
negative regulation of cell migrationGO:00303361020.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
negative regulation of cytokine productionGO:0001818820.014
peripheral nervous system developmentGO:000742220.014
small molecule biosynthetic processGO:00442831570.014
negative regulation of synaptic transmissionGO:005080520.014
regulation of wnt signaling pathwayGO:00301111230.014
purine nucleotide biosynthetic processGO:0006164840.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
receptor metabolic processGO:0043112810.014
photoreceptor cell differentiationGO:004653020.014
reproductive processGO:00224141060.014
positive regulation of gtpase activityGO:00435471660.013
spermatid developmentGO:000728640.013
cellular response to lipidGO:00713961270.013
response to bacteriumGO:00096171440.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
ossificationGO:00015031210.013
regulation of protein modification by small protein conjugation or removalGO:19033201070.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
response to steroid hormoneGO:0048545800.013
positive regulation of response to external stimulusGO:0032103880.013
negative regulation of organelle organizationGO:00106391260.013
ribose phosphate biosynthetic processGO:0046390820.013
oocyte differentiationGO:000999420.013
negative regulation of cell motilityGO:20001461040.013
regulation of intracellular protein transportGO:00331571230.013
regulation of viral processGO:00507921030.013
tripartite regional subdivisionGO:000735120.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
gtp catabolic processGO:00061842370.013
positive regulation of cytokine productionGO:00018191670.013
viral life cycleGO:00190581320.013
cell projection morphogenesisGO:00488581290.013
alcohol metabolic processGO:00060661140.013
neuron developmentGO:00486661130.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of cell adhesionGO:00301551660.013
response to hypoxiaGO:0001666960.013
head developmentGO:00603221080.013
peptidyl serine modificationGO:00182091060.013
nuclear importGO:00511701060.013
protein localization to plasma membraneGO:0072659930.013
positive regulation of transmembrane transportGO:0034764410.013
behavioral response to ethanolGO:004814920.013
chemotaxisGO:00069351570.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
heart developmentGO:0007507950.013
rna processingGO:00063962550.013
proteasomal protein catabolic processGO:00104981760.013
single organismal cell cell adhesionGO:00163371480.013
gland developmentGO:0048732480.013
microtubule based processGO:00070172100.013
response to fungusGO:000962040.013
digestive tract developmentGO:0048565750.013
positive regulation of gtp catabolic processGO:00331261660.013
endocytosisGO:00068971590.013
cellular amide metabolic processGO:0043603690.012
modification dependent macromolecule catabolic processGO:00436322120.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of nucleotide catabolic processGO:00308112050.012
negative regulation of protein maturationGO:19033181420.012
positive regulation of protein transportGO:00512221350.012
atp metabolic processGO:00460341760.012
sodium ion transportGO:0006814610.012
cytokinesisGO:0000910960.012
anatomical structure homeostasisGO:00602491000.012
serotonin uptakeGO:005161020.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
syncytium formation by plasma membrane fusionGO:000076820.012

PKDREJ disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.035
nervous system diseaseDOID:8634310.035
eye diseaseDOID:56141490.026
eye and adnexa diseaseDOID:14921500.026
retinal diseaseDOID:56791180.019
disease of metabolismDOID:00146672950.018
musculoskeletal system diseaseDOID:172230.017
central nervous system diseaseDOID:3311860.014
inherited metabolic disorderDOID:6552420.014
disease of cellular proliferationDOID:145661740.013