Homo sapiens

29 known processes

TREX1

three prime repair exonuclease 1

(Aliases: AGS1,DRN3,CRV,DKFZp434J0310,HERNS)

TREX1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238110.061
cellular amino acid metabolic processGO:00065201160.038
post embryonic developmentGO:000979120.038
organonitrogen compound biosynthetic processGO:19015662000.035
determination of adult lifespanGO:000834020.034
cellular amine metabolic processGO:0044106410.033
amine metabolic processGO:0009308440.033
ras protein signal transductionGO:0007265730.033
nucleoside phosphate catabolic processGO:19012924120.031
nucleoside phosphate biosynthetic processGO:19012931090.030
positive regulation of cellular amino acid metabolic processGO:004576430.030
small gtpase mediated signal transductionGO:0007264780.029
nucleoside triphosphate metabolic processGO:00091414220.029
nucleoside catabolic processGO:00091644080.029
regulation of cellular amino acid metabolic processGO:000652160.029
negative regulation of catalytic activityGO:00430863350.029
multicellular organismal agingGO:001025930.029
organophosphate biosynthetic processGO:00904071630.028
cellular ketone metabolic processGO:0042180800.028
organophosphate catabolic processGO:00464344300.028
regulation of kinase activityGO:00435493140.027
modification dependent protein catabolic processGO:00199412090.027
cellular macromolecule catabolic processGO:00442653800.027
Human
cellular macromolecular complex assemblyGO:00346223240.025
cellular response to dna damage stimulusGO:00069743790.025
regulation of cellular ketone metabolic processGO:0010565500.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
chemical homeostasisGO:00488783060.025
female gamete generationGO:000729220.024
purine containing compound catabolic processGO:00725234110.024
purine ribonucleoside metabolic processGO:00461284370.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
response to external biotic stimulusGO:00432072610.023
carbohydrate derivative biosynthetic processGO:19011372070.023
glycosyl compound catabolic processGO:19016584130.023
nucleoside triphosphate catabolic processGO:00091433940.023
nucleotide catabolic processGO:00091664080.022
ribonucleoside catabolic processGO:00424544060.022
ribonucleotide catabolic processGO:00092614050.022
protein modification by small protein conjugationGO:00324463420.022
regulation of transferase activityGO:00513383550.022
mitotic cell cycleGO:00002783260.022
protein processingGO:00164852260.021
protein catabolic processGO:00301633250.021
carbohydrate metabolic processGO:00059752070.021
response to abiotic stimulusGO:00096283360.021
negative regulation of cellular protein metabolic processGO:00322693530.021
positive regulation of phosphorylationGO:00423273940.021
negative regulation of protein metabolic processGO:00512483910.021
purine nucleotide catabolic processGO:00061954050.021
purine ribonucleotide catabolic processGO:00091544040.021
cellular protein catabolic processGO:00442572610.021
negative regulation of phosphorus metabolic processGO:00105632670.021
lipid metabolic processGO:00066293810.021
cytoplasmic transportGO:00164823790.021
protein acylationGO:00435431380.020
cellular lipid metabolic processGO:00442553030.020
positive regulation of cellular catabolic processGO:00313312840.020
purine ribonucleoside catabolic processGO:00461303980.020
immune effector processGO:00022521590.020
positive regulation of transportGO:00510503360.020
cellular protein complex assemblyGO:00436231880.020
metal ion transportGO:00300012720.020
regulation of cytoskeleton organizationGO:00514931770.019
mitotic cell cycle processGO:19030472860.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
oogenesisGO:004847720.019
regulation of protein kinase activityGO:00458592890.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
positive regulation of cellular amine metabolic processGO:003324070.019
apoptotic signaling pathwayGO:00971902680.019
purine nucleotide biosynthetic processGO:0006164840.018
purine nucleoside catabolic processGO:00061523980.018
positive regulation of apoptotic processGO:00430652460.018
intracellular protein transportGO:00068862700.018
cell morphogenesisGO:00009022960.018
biological adhesionGO:00226103310.018
ubiquitin dependent protein catabolic processGO:00065112060.018
gtp catabolic processGO:00061842370.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
cell adhesionGO:00071553250.018
negative regulation of phosphate metabolic processGO:00459362670.018
defense response to other organismGO:00985421290.018
positive regulation of hydrolase activityGO:00513453310.017
viral life cycleGO:00190581320.017
positive regulation of protein phosphorylationGO:00019343130.017
regulation of establishment of protein localizationGO:00702012420.017
system processGO:00030083490.017
immune responseGO:00069553070.017
glycoprotein metabolic processGO:00091001100.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
regenerationGO:003109940.017
membrane organizationGO:00610242920.016
protein glycosylationGO:0006486620.016
proteasomal protein catabolic processGO:00104981760.016
cellular component morphogenesisGO:00329893140.016
innate immune responseGO:00450871780.016
multi organism cellular processGO:00447641560.016
single organism membrane organizationGO:00448022680.016
protein lipidationGO:0006497330.016
negative regulation of cell deathGO:00605483450.016
regulation of immune effector processGO:0002697910.016
purine containing compound biosynthetic processGO:0072522880.016
single organism carbohydrate metabolic processGO:00447231930.016
guanosine containing compound metabolic processGO:19010682440.016
nucleotide biosynthetic processGO:00091651090.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
negative regulation of protein modification processGO:00314002000.016
single organism cellular localizationGO:19025803320.016
rho protein signal transductionGO:0007266260.016
macromolecule glycosylationGO:0043413630.016
cell projection organizationGO:00300302520.015
regulation of protein localizationGO:00328802960.015
positive regulation of transferase activityGO:00513472270.015
defense responseGO:00069523150.015
positive regulation of cell deathGO:00109422630.015
regulation of protein catabolic processGO:00421761550.015
cellular response to cytokine stimulusGO:00713451810.015
negative regulation of cellular amine metabolic processGO:003323930.015
regulation of cellular response to stressGO:00801352440.015
regulation of protein transportGO:00512232130.015
microtubule based processGO:00070172100.015
positive regulation of cellular component organizationGO:00511303760.015
regulation of cell activationGO:00508651250.015
nervous system developmentGO:00073992930.015
negative regulation of multicellular organismal processGO:00512413170.015
vesicle mediated transportGO:00161923710.014
regulation of cell cycleGO:00517263930.014
protein oligomerizationGO:00512591730.014
mitochondrion organizationGO:00070051560.014
gtp metabolic processGO:00460392390.014
cell projection assemblyGO:00300311260.014
protein ubiquitinationGO:00165673140.014
oxidation reduction processGO:00551143960.014
regulation of nucleotide metabolic processGO:00061402690.014
negative regulation of cell cycleGO:00457861930.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of proteolysisGO:00301622930.014
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.014
cellular response to external stimulusGO:00714961110.014
positive regulation of kinase activityGO:00336742040.014
regulation of mapk cascadeGO:00434082620.014
maintenance of locationGO:00512351120.014
regulation of purine nucleotide metabolic processGO:19005422640.014
regulation of cellular component movementGO:00512703340.014
regulation of ion transportGO:00432691890.014
locomotory behaviorGO:000762610.014
positive regulation of protein kinase activityGO:00458601900.014
response to other organismGO:00517072610.013
protein localization to organelleGO:00333652800.013
lipid biosynthetic processGO:00086101770.013
organelle assemblyGO:00709251760.013
regulation of purine nucleotide catabolic processGO:00331212050.013
chromatin organizationGO:00063253510.013
regulation of anatomical structure morphogenesisGO:00226032860.013
chromatin modificationGO:00165682980.013
segmentationGO:003528240.013
regulation of cytokine productionGO:00018172320.013
dephosphorylationGO:00163112090.013
guanosine containing compound catabolic processGO:19010692390.013
regulation of intracellular transportGO:00323861950.013
cation transportGO:00068123310.013
positive regulation of locomotionGO:00400171860.013
divalent inorganic cation transportGO:00725111580.013
regulation of cellular component biogenesisGO:00440872810.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
response to radiationGO:00093141510.013
negative regulation of immune system processGO:00026831360.013
negative regulation of phosphorylationGO:00423261740.013
spermatid differentiationGO:004851540.013
signal transduction by phosphorylationGO:00230142970.013
regulation of protein maturationGO:19033171500.013
regulation of dna metabolic processGO:00510521530.013
regulation of cell cycle processGO:00105642660.013
regulation of protein complex assemblyGO:00432541470.012
neuromuscular junction developmentGO:000752830.012
regulation of actin filament based processGO:00329701410.012
positive regulation of organelle organizationGO:00106381950.012
small molecule biosynthetic processGO:00442831570.012
nitrogen compound transportGO:00717051910.012
modification dependent macromolecule catabolic processGO:00436322120.012
protein maturationGO:00516042330.012
peripheral nervous system developmentGO:000742220.012
negative regulation of organelle organizationGO:00106391260.012
memoryGO:000761330.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
cellular chemical homeostasisGO:00550821800.012
regulation of cell migrationGO:00303342890.012
cellular homeostasisGO:00197251960.012
actin cytoskeleton organizationGO:00300362070.012
neurological system processGO:00508771630.012
positive regulation of immune system processGO:00026842830.012
negative regulation of proteolysisGO:00458611320.012
mapk cascadeGO:00001652880.012
cell cycle phase transitionGO:00447701730.012
cell growthGO:00160491600.012
negative regulation of apoptotic processGO:00430663160.012
regulation of synaptic plasticityGO:004816730.012
positive regulation of cytokine productionGO:00018191670.012
spermatid developmentGO:000728640.012
interspecies interaction between organismsGO:00444191560.012
organic acid biosynthetic processGO:0016053970.012
cellular cation homeostasisGO:00300031630.012
nucleocytoplasmic transportGO:00069131760.012
microtubule cytoskeleton organizationGO:00002261760.012
histone modificationGO:00165702510.012
cellular ion homeostasisGO:00068731680.012
response to biotic stimulusGO:00096072760.011
actin filament based processGO:00300292240.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
regulation of mitotic cell cycleGO:00073461890.011
nucleoside monophosphate metabolic processGO:00091231910.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
positive regulation of programmed cell deathGO:00430682490.011
negative regulation of transportGO:00510511760.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
posttranscriptional regulation of gene expressionGO:00106082130.011
regulation of gtpase activityGO:00430871800.011
positive regulation of nucleotide catabolic processGO:00308131850.011
dna repairGO:00062811980.011
peptidyl tyrosine modificationGO:00182121700.011
cellular response to oxygen containing compoundGO:19017012760.011
lipoprotein metabolic processGO:0042157420.011
organic hydroxy compound metabolic processGO:19016151470.011
negative regulation of protein maturationGO:19033181420.011
immune system developmentGO:00025201950.011
negative regulation of programmed cell deathGO:00430693210.011
inorganic ion transmembrane transportGO:00986602310.011
plasma membrane organizationGO:00070091150.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of membrane potentialGO:0042391950.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
regulation of cell motilityGO:20001452990.011
regulation of nucleoside metabolic processGO:00091182090.011
peptidyl tyrosine phosphorylationGO:00181081700.011
divalent metal ion transportGO:00708381520.011
regulation of homeostatic processGO:00328441210.011
rna processingGO:00063962550.011
covalent chromatin modificationGO:00165692540.011
negative regulation of cellular component organizationGO:00511292350.011
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of peptidase activityGO:00525471800.011
positive regulation of nucleotide metabolic processGO:00459812300.010
protein targetingGO:00066051870.010
regulation of cell differentiationGO:00455953930.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
regulation of cell growthGO:00015581350.010
leukocyte mediated immunityGO:0002443590.010
secretionGO:00469032540.010
compound eye developmentGO:004874910.010
endosomal transportGO:00161971290.010
carboxylic acid biosynthetic processGO:0046394970.010
regulation of secretionGO:00510461940.010
regulation of growthGO:00400081650.010
nuclear transportGO:00511691790.010
cofactor metabolic processGO:0051186870.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
regulation of nucleotide catabolic processGO:00308112050.010
negative regulation of protein phosphorylationGO:00019331400.010
regulation of gtp catabolic processGO:00331241800.010
negative regulation of catabolic processGO:00098951040.010
mitotic cell cycle phase transitionGO:00447721620.010
negative regulation of transferase activityGO:00513481240.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
regulation of cell adhesionGO:00301551660.010
regulation of transmembrane transportGO:00347621390.010

TREX1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.042
nervous system diseaseDOID:8634310.022
sensory system diseaseDOID:00501552030.022
eye diseaseDOID:56141490.022
eye and adnexa diseaseDOID:14921500.022
musculoskeletal system diseaseDOID:172230.017
cancerDOID:1621670.015
disease of cellular proliferationDOID:145661740.015
organ system cancerDOID:00506861640.015
inherited metabolic disorderDOID:6552420.014
central nervous system diseaseDOID:3311860.013
connective tissue diseaseDOID:651090.011
immune system diseaseDOID:29141550.008
hypersensitivity reaction diseaseDOID:0060056250.002
hypersensitivity reaction type ii diseaseDOID:417190.002
lupus erythematosusDOID:8857120.001
systemic lupus erythematosusDOID:9074120.001
aicardi goutieres syndromeDOID:005062970.001