Homo sapiens

285 known processes

AKR1C3

aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)

(Aliases: hluPGFS,DDX,KIAA0119,DD3,HA1753,HAKRB,HAKRe,HSD17B5,PGFS)

AKR1C3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
androgen biosynthetic processGO:000670231.000
retinoic acid biosynthetic processGO:000213821.000
testosterone biosynthetic processGO:006137021.000
regulation of testosterone biosynthetic processGO:200022421.000
diterpenoid biosynthetic processGO:001610221.000
ketone catabolic processGO:004218231.000
primary alcohol catabolic processGO:003431031.000
sterol catabolic processGO:001612731.000
Human
retinoid metabolic processGO:0001523180.999
cellular response to prostaglandin stimulusGO:007137940.999
primary alcohol metabolic processGO:0034308170.999
glycoside metabolic processGO:0016137130.998
doxorubicin metabolic processGO:004459880.998
isoprenoid catabolic processGO:000830070.994
cholesterol catabolic processGO:000670730.993
Human
progesterone metabolic processGO:004244860.991
response to jasmonic acidGO:000975340.988
cellular response to jasmonic acid stimulusGO:007139540.987
hormone catabolic processGO:004244740.986
regulation of retinoic acid biosynthetic processGO:190005210.983
sesquiterpenoid metabolic processGO:000671430.979
farnesol catabolic processGO:001648820.966
regulation of isoprenoid metabolic processGO:001974710.963
retinal metabolic processGO:004257480.962
daunorubicin metabolic processGO:004459780.960
prostanoid metabolic processGO:0006692170.947
regulation of ketone biosynthetic processGO:001056670.937
diterpenoid metabolic processGO:0016101200.903
aminoglycoside antibiotic metabolic processGO:003064780.902
terpenoid metabolic processGO:0006721270.895
farnesol metabolic processGO:001648720.893
bile acid metabolic processGO:0008206140.878
Human
vitamin metabolic processGO:0006766260.878
limbic system developmentGO:002176130.857
Rat
icosanoid metabolic processGO:0006690350.853
sesquiterpenoid catabolic processGO:001610720.847
terpenoid biosynthetic processGO:001611420.832
terpenoid catabolic processGO:001611550.822
response to prostaglandinGO:003469480.810
negative regulation of isoprenoid metabolic processGO:004582710.789
bile acid biosynthetic processGO:0006699100.777
Human
fatty acid derivative metabolic processGO:1901568350.774
ketone biosynthetic processGO:0042181170.762
cellular hormone metabolic processGO:0034754410.744
retinoic acid metabolic processGO:004257370.741
quinone metabolic processGO:1901661180.739
lipid catabolic processGO:0016042840.720
oxidation reduction processGO:00551143960.717
response to fatty acidGO:0070542130.692
cellular lipid catabolic processGO:0044242650.687
steroid catabolic processGO:0006706100.676
Human
cellular aldehyde metabolic processGO:0006081200.658
alcohol metabolic processGO:00060661140.638
polyketide metabolic processGO:003063880.632
g protein coupled receptor signaling pathwayGO:00071862070.624
cellular response to calcium ionGO:0071277190.616
hippocampus developmentGO:002176610.613
Rat
cofactor metabolic processGO:0051186870.609
isoprenoid metabolic processGO:0006720390.587
lipid biosynthetic processGO:00086101770.586
organic acid biosynthetic processGO:0016053970.584
parturitionGO:000756710.579
negative regulation of retinoic acid biosynthetic processGO:190005310.572
unsaturated fatty acid metabolic processGO:0033559370.570
steroid metabolic processGO:0008202940.556
carboxylic acid biosynthetic processGO:0046394970.538
small molecule biosynthetic processGO:00442831570.537
negative regulation of lipid metabolic processGO:0045833380.527
cellular response to corticosteroid stimulusGO:007138450.524
small molecule catabolic processGO:0044282920.523
hormone metabolic processGO:0042445610.521
organic hydroxy compound catabolic processGO:1901616220.511
digestionGO:0007586220.508
Human
fatty acid metabolic processGO:00066311150.479
regulation of cellular ketone metabolic processGO:0010565500.477
cellular lipid metabolic processGO:00442553030.467
prostaglandin metabolic processGO:0006693170.464
lipid metabolic processGO:00066293810.450
steroid biosynthetic processGO:0006694460.449
isoprenoid biosynthetic processGO:000829990.427
regulation of vitamin metabolic processGO:003065690.419
androgen metabolic processGO:000820990.417
organic hydroxy compound metabolic processGO:19016151470.408
monocarboxylic acid biosynthetic processGO:0072330670.408
cellular response to fatty acidGO:007139880.403
secondary metabolic processGO:0019748170.399
multicellular organismal metabolic processGO:0044236340.396
cellular response to oxidative stressGO:0034599850.396
cellular ketone metabolic processGO:0042180800.373
regulation of endothelial cell apoptotic processGO:2000351240.360
regulation of hormone levelsGO:00108171250.358
response to calcium ionGO:0051592460.350
keratinocyte differentiationGO:0030216360.322
hormone biosynthetic processGO:0042446220.317
protein homooligomerizationGO:00512601000.317
Human
cholesterol metabolic processGO:0008203280.311
Human
regulation of reactive oxygen species metabolic processGO:2000377410.308
positive regulation of cell proliferationGO:00082843010.305
response to hormoneGO:00097251750.305
regulation of hormone metabolic processGO:0032350140.303
response to oxidative stressGO:00069791210.293
protein localization to organelleGO:00333652800.276
positive regulation of apoptotic processGO:00430652460.273
organic hydroxy compound biosynthetic processGO:1901617710.272
reactive oxygen species metabolic processGO:0072593750.267
sterol metabolic processGO:0016125280.262
Human
negative regulation of vitamin metabolic processGO:004613760.245
regulation of lipid biosynthetic processGO:0046890470.239
response to organic cyclic compoundGO:00140702040.239
cytoplasmic transportGO:00164823790.236
cellular response to organic cyclic compoundGO:00714071270.236
cell type specific apoptotic processGO:00972851250.234
negative regulation of hormone metabolic processGO:003235160.234
protein oligomerizationGO:00512591730.233
Human
positive regulation of programmed cell deathGO:00430682490.232
regulation of alcohol biosynthetic processGO:1902930220.231
regulation of hormone biosynthetic processGO:0046885100.228
response to estrogenGO:0043627470.225
Rat
cellular response to reactive oxygen speciesGO:0034614500.217
response to organophosphorusGO:0046683410.213
Human
cellular response to oxygen containing compoundGO:19017012760.211
c21 steroid hormone metabolic processGO:0008207170.211
cellular response to metal ionGO:0071248430.211
response to steroid hormoneGO:0048545800.207
positive regulation of endothelial cell apoptotic processGO:200035380.206
protein targetingGO:00066051870.205
cellular response to nutrient levelsGO:0031669690.204
positive regulation of reactive oxygen species metabolic processGO:2000379240.202
single organism cellular localizationGO:19025803320.198
regulation of steroid metabolic processGO:0019218320.197
cellular response to external stimulusGO:00714961110.195
rna processingGO:00063962550.193
epidermal cell differentiationGO:0009913450.190
regulation of lipid metabolic processGO:0019216960.190
response to lipidGO:00339932060.185
epithelial cell differentiationGO:00308551410.184
endothelial cell apoptotic processGO:0072577260.183
cellular response to endogenous stimulusGO:00714953360.183
cellular response to acid chemicalGO:0071229440.181
mrna processingGO:00063971330.175
protein targeting to nucleusGO:00447441040.173
positive regulation of cell deathGO:00109422630.171
single organism nuclear importGO:19025931040.170
nuclear transportGO:00511691790.169
response to inorganic substanceGO:00100351270.169
intracellular receptor signaling pathwayGO:00305221040.167
response to metal ionGO:0010038840.167
male gonad developmentGO:0008584230.164
multicellular organismal macromolecule metabolic processGO:0044259290.163
development of primary male sexual characteristicsGO:0046546230.154
regulation of steroid biosynthetic processGO:0050810230.153
cellular response to starvationGO:0009267580.153
alcohol biosynthetic processGO:0046165520.152
negative regulation of lipid biosynthetic processGO:0051055220.148
response to oxygen containing compoundGO:19017003690.147
cellular response to inorganic substanceGO:0071241450.146
cellular response to hormone stimulusGO:00328701250.145
establishment of protein localization to organelleGO:00725941720.144
protein import into nucleusGO:00066061040.143
response to drugGO:0042493810.141
Rat
cellular response to lipidGO:00713961270.138
epidermis developmentGO:0008544590.138
cellular response to steroid hormone stimulusGO:0071383370.137
skin developmentGO:0043588760.135
protein localization to nucleusGO:00345041360.134
response to nutrientGO:0007584200.131
epithelium developmentGO:00604292270.131
retinoic acid receptor signaling pathwayGO:0048384130.127
regulation of retinoic acid receptor signaling pathwayGO:004838590.124
nucleocytoplasmic transportGO:00069131760.122
response to reactive oxygen speciesGO:0000302610.119
male sex differentiationGO:0046661250.119
response to extracellular stimulusGO:0009991850.115
alcohol catabolic processGO:0046164200.110
response to acid chemicalGO:0001101660.109
nuclear importGO:00511701060.109
mrna metabolic processGO:00160711750.109
protein kinase b signalingGO:0043491690.098
telencephalon developmentGO:0021537170.094
Rat
protein importGO:00170381300.092
cellular amino acid metabolic processGO:00065201160.092
negative regulation of mrna metabolic processGO:1903312150.091
response to corticosteroidGO:0031960150.089
response to cadmium ionGO:0046686100.088
response to starvationGO:0042594590.082
nervous system developmentGO:00073992930.082
Rat
head developmentGO:00603221080.082
Rat
cellular response to extracellular stimulusGO:0031668720.075
brain developmentGO:0007420970.074
Rat
response to nutrient levelsGO:0031667810.072
regulation of protein kinase b signalingGO:0051896610.071
rna splicing via transesterification reactionsGO:0000375900.064
central nervous system developmentGO:00074171230.053
Rat
locomotory behaviorGO:000762610.051
glycosyl compound catabolic processGO:19016584130.048
protein import into nucleus translocationGO:0000060220.047
purine ribonucleoside metabolic processGO:00461284370.044
negative regulation of rna splicingGO:0033119150.044
cellular macromolecule catabolic processGO:00442653800.043
system processGO:00030083490.043
amine metabolic processGO:0009308440.041
determination of adult lifespanGO:000834020.040
nucleoside triphosphate metabolic processGO:00091414220.040
regulation of mrna processingGO:0050684480.040
post embryonic developmentGO:000979120.040
purine ribonucleoside catabolic processGO:00461303980.039
purine nucleotide catabolic processGO:00061954050.038
forebrain developmentGO:0030900260.037
Rat
blastoderm segmentationGO:000735020.037
monocarboxylic acid metabolic processGO:00327871850.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
neuromuscular junction developmentGO:000752830.036
regulation of cellular component biogenesisGO:00440872810.036
reproductive system developmentGO:0061458560.035
nucleotide catabolic processGO:00091664080.035
organonitrogen compound biosynthetic processGO:19015662000.035
multicellular organismal agingGO:001025930.034
purine containing compound catabolic processGO:00725234110.034
ribonucleoside catabolic processGO:00424544060.033
regulation of cellular amino acid metabolic processGO:000652160.033
lung alveolus developmentGO:004828640.032
negative regulation of mrna splicing via spliceosomeGO:0048025110.031
guanosine containing compound metabolic processGO:19010682440.030
actin filament based processGO:00300292240.030
sulfur compound metabolic processGO:00067901010.030
negative regulation of phosphate metabolic processGO:00459362670.030
nucleoside catabolic processGO:00091644080.029
segmentationGO:003528240.029
female gamete generationGO:000729220.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
negative regulation of cell deathGO:00605483450.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
cellular amine metabolic processGO:0044106410.028
startle responseGO:000196430.028
positive regulation of transportGO:00510503360.028
memoryGO:000761330.028
nucleoside phosphate catabolic processGO:19012924120.028
adult locomotory behaviorGO:000834410.027
positive regulation of cellular amine metabolic processGO:003324070.027
regulation of synaptic plasticityGO:004816730.027
oogenesisGO:004847720.027
gtp metabolic processGO:00460392390.027
nucleoside triphosphate catabolic processGO:00091433940.027
purine nucleoside catabolic processGO:00061523980.027
maintenance of locationGO:00512351120.026
organophosphate catabolic processGO:00464344300.026
negative regulation of apoptotic processGO:00430663160.026
secretion by cellGO:00329402260.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
purine nucleoside triphosphate catabolic processGO:00091463920.026
positive regulation of cellular component organizationGO:00511303760.026
negative regulation of protein metabolic processGO:00512483910.026
rna splicingGO:00083801310.026
membrane organizationGO:00610242920.025
negative regulation of catalytic activityGO:00430863350.025
ribonucleoside triphosphate metabolic processGO:00091994120.024
peripheral nervous system developmentGO:000742220.024
negative regulation of phosphorus metabolic processGO:00105632670.024
protein ubiquitinationGO:00165673140.024
cytokine productionGO:00018162470.024
reproductive processGO:00224141060.023
circadian behaviorGO:004851220.023
signal transduction by phosphorylationGO:00230142970.023
cellular response to cadmium ionGO:007127680.023
purine ribonucleotide catabolic processGO:00091544040.023
transmembrane transportGO:00550853990.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
carbohydrate derivative biosynthetic processGO:19011372070.022
anterior posterior axis specificationGO:000994820.022
anterior posterior axis specification embryoGO:000859520.022
tripartite regional subdivisionGO:000735120.022
negative regulation of cellular protein metabolic processGO:00322693530.022
negative regulation of programmed cell deathGO:00430693210.022
regenerationGO:003109940.022
oocyte developmentGO:004859910.021
response to abiotic stimulusGO:00096283360.021
single organism reproductive processGO:0044702980.021
meiotic chromosome segregationGO:004513240.021
ion homeostasisGO:00508012300.021
reproductive structure developmentGO:0048608550.021
intracellular mrna localizationGO:000829810.021
regulation of cell maturationGO:190342930.020
mapk cascadeGO:00001652880.020
negative regulation of cellular component organizationGO:00511292350.020
cation homeostasisGO:00550801890.020
guanosine containing compound catabolic processGO:19010692390.020
regulation of cellular response to stressGO:00801352440.020
regulation of cellular amine metabolic processGO:0033238110.020
reactive oxygen species biosynthetic processGO:190340940.020
regulation of peptidase activityGO:00525471800.020
single organism membrane organizationGO:00448022680.020
protein processingGO:00164852260.019
rhythmic behaviorGO:000762220.019
protein maturationGO:00516042330.019
apoptotic signaling pathwayGO:00971902680.019
mitotic cell cycleGO:00002783260.019
pituitary gland developmentGO:002198320.019
spermatid differentiationGO:004851540.019
cell developmentGO:00484683280.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
coenzyme metabolic processGO:0006732650.019
ras protein signal transductionGO:0007265730.019
neurological system processGO:00508771630.019
negative regulation of protein modification processGO:00314002000.019
cellular amide metabolic processGO:0043603690.019
regulation of protein transportGO:00512232130.019
biological adhesionGO:00226103310.019
regulation of cell differentiationGO:00455953930.019
small gtpase mediated signal transductionGO:0007264780.019
oocyte differentiationGO:000999420.019
tissue regenerationGO:004224630.019
i kappab kinase nf kappab signalingGO:00072491660.019
development of primary sexual characteristicsGO:0045137350.019
protein modification by small protein conjugationGO:00324463420.019
regulation of cell cycle processGO:00105642660.018
modification dependent macromolecule catabolic processGO:00436322120.018
intracellular protein transportGO:00068862700.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
ribonucleotide catabolic processGO:00092614050.018
cardiac muscle cell contractionGO:008600340.018
response to growth factorGO:00708482050.018
gtp catabolic processGO:00061842370.018
regulation of reactive oxygen species biosynthetic processGO:190342630.018
visual learningGO:000854210.018
morphogenesis of embryonic epitheliumGO:001633140.018
cellular protein catabolic processGO:00442572610.018
spermatid developmentGO:000728640.018
regulation of secretion by cellGO:19035301770.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of protein localizationGO:00328802960.017
positive regulation of nucleotide metabolic processGO:00459812300.017
cell morphogenesisGO:00009022960.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of neuronal synaptic plasticityGO:004816810.017
regulation of proteolysisGO:00301622930.017
cellular protein complex assemblyGO:00436231880.017
nucleoside phosphate biosynthetic processGO:19012931090.017
positive regulation of gliogenesisGO:001401540.017
regulation of cellular component movementGO:00512703340.017
sex differentiationGO:0007548450.017
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122830.017
regulation of protein maturationGO:19033171500.017
regulation of protein kinase activityGO:00458592890.017
protein catabolic processGO:00301633250.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
positive regulation of glial cell proliferationGO:006025220.016
cell projection organizationGO:00300302520.016
extrinsic apoptotic signaling pathwayGO:00971911190.016
regulation of immune responseGO:00507762010.016
protein localization to membraneGO:00726571600.016
modification dependent protein catabolic processGO:00199412090.016
regulation of cytokine productionGO:00018172320.016
regulation of cell cycleGO:00517263930.016
cellular modified amino acid metabolic processGO:0006575640.016
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.016
proteasomal protein catabolic processGO:00104981760.016
regulation of protein processingGO:00706131500.016
positive regulation of cellular catabolic processGO:00313312840.016
matingGO:000761810.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
microtubule cytoskeleton organizationGO:00002261760.016
reactive nitrogen species metabolic processGO:200105730.016
negative regulation of protein maturationGO:19033181420.016
defense responseGO:00069523150.016
rho protein signal transductionGO:0007266260.016
positive regulation of proteolysisGO:00458621420.016
positive regulation of immune system processGO:00026842830.016
regulation of secretionGO:00510461940.016
positive regulation of cell differentiationGO:00455972110.016
negative regulation of protein processingGO:00109551420.016
organophosphate biosynthetic processGO:00904071630.016
ubiquitin dependent protein catabolic processGO:00065112060.016
negative regulation of cellular amine metabolic processGO:003323930.016
nucleotide biosynthetic processGO:00091651090.016
engulfment of apoptotic cellGO:004365220.016
negative regulation of transportGO:00510511760.015
positive regulation of hydrolase activityGO:00513453310.015
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
glial cell migrationGO:000834740.015
regulation of anatomical structure morphogenesisGO:00226032860.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of nucleoside metabolic processGO:00459791860.015
negative regulation of t cell apoptotic processGO:007023340.015
immune effector processGO:00022521590.015
cellular component morphogenesisGO:00329893140.015
9 cis retinoic acid metabolic processGO:004290510.015
carbohydrate metabolic processGO:00059752070.015
innate immune responseGO:00450871780.015
regulation of purine nucleotide metabolic processGO:19005422640.015
cofactor biosynthetic processGO:0051188310.015
dicarboxylic acid metabolic processGO:0043648290.015
immune responseGO:00069553070.015
regulation of rna splicingGO:0043484620.015
inner ear morphogenesisGO:004247240.015
negative regulation of phosphorylationGO:00423261740.015
response to biotic stimulusGO:00096072760.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
trabecula morphogenesisGO:006138320.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
motor neuron axon guidanceGO:000804520.014
sensory perception of smellGO:000760820.014
cellular homeostasisGO:00197251960.014
cell fate determinationGO:000170930.014
epidermis morphogenesisGO:004873030.014
regulation of apoptotic signaling pathwayGO:20012331750.014
positive regulation of secretion by cellGO:19035321080.014
nucleus localizationGO:005164710.014
positive regulation of protein phosphorylationGO:00019343130.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
purine nucleotide biosynthetic processGO:0006164840.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
cell growthGO:00160491600.014
positive regulation of transferase activityGO:00513472270.014
associative learningGO:000830610.014
regulation of protein complex assemblyGO:00432541470.014
apoptotic mitochondrial changesGO:0008637570.014
regulation of nucleoside metabolic processGO:00091182090.014
ion transmembrane transportGO:00342203380.014
visual behaviorGO:000763220.014
compound eye developmentGO:004874910.014
dephosphorylationGO:00163112090.014
morphogenesis of a polarized epitheliumGO:000173830.014
embryonic epithelial tube formationGO:000183840.014
chromosome segregationGO:00070591140.014
actin cytoskeleton organizationGO:00300362070.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
inorganic ion transmembrane transportGO:00986602310.014
gonad developmentGO:0008406340.014
nitrogen compound transportGO:00717051910.014
melanin metabolic processGO:000658210.014
positive regulation of vasoconstrictionGO:004590730.014
response to nitrogen compoundGO:19016981840.014
cation transmembrane transportGO:00986552380.013
regulation of purine nucleotide catabolic processGO:00331212050.013
negative regulation of intracellular signal transductionGO:19025321830.013
syncytium formation by plasma membrane fusionGO:000076820.013
regulation of kinase activityGO:00435493140.013
positive regulation of secretionGO:00510471160.013
regulation of growthGO:00400081650.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
cellular macromolecular complex assemblyGO:00346223240.013
mitotic cell cycle processGO:19030472860.013
negative regulation of cell cycleGO:00457861930.013
regulation of glial cell proliferationGO:006025140.013
atp metabolic processGO:00460341760.013
multi organism reproductive processGO:0044703540.013
positive regulation of kinase activityGO:00336742040.013
purine ribonucleotide biosynthetic processGO:0009152790.013
striated muscle cell apoptotic processGO:001065830.013
regulation of meiotic cell cycleGO:005144540.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
cell cycle phase transitionGO:00447701730.013
organelle assemblyGO:00709251760.013
cellular response to dna damage stimulusGO:00069743790.013
dna repairGO:00062811980.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of neural precursor cell proliferationGO:200017740.013
skeletal muscle tissue growthGO:004863020.013
sequestering of metal ionGO:0051238240.013
negative regulation of multicellular organismal processGO:00512413170.012
positive regulation of catabolic processGO:00098963100.012
cellular ion homeostasisGO:00068731680.012
actin mediated cell contractionGO:0070252120.012
microtubule based processGO:00070172100.012
sulfur compound biosynthetic processGO:0044272380.012
regulation of cell migrationGO:00303342890.012

AKR1C3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
chromosomal diseaseDOID:0080014160.192
Human
gonadal dysgenesisDOID:1444780.072
Human
46 xy gonadal dysgenesisDOID:1444880.072
Human
disease of metabolismDOID:00146672950.034
Human
musculoskeletal system diseaseDOID:172230.032
sensory system diseaseDOID:00501552030.029
eye diseaseDOID:56141490.029
nervous system diseaseDOID:8634310.029
eye and adnexa diseaseDOID:14921500.029
cardiovascular system diseaseDOID:12871060.026
immune system diseaseDOID:29141550.025
central nervous system diseaseDOID:3311860.022
muscular diseaseDOID:00800001140.020
muscle tissue diseaseDOID:661130.020
myopathyDOID:4231040.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.017
cancerDOID:1621670.017
retinal diseaseDOID:56791180.016
connective tissue diseaseDOID:651090.015
neurodegenerative diseaseDOID:12891020.015
heart diseaseDOID:114680.014
retinal degenerationDOID:8466890.014
bone diseaseDOID:0080001880.013
hematopoietic system diseaseDOID:741000.012