Homo sapiens

171 known processes

GCK

glucokinase (hexokinase 4)

(Aliases: LGLK,HKIV,GLK,HK4,MODY2,HHF3,FGQTL3,GK,HXKP)

GCK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chemical homeostasisGO:00488783060.262
urate metabolic processGO:0046415110.186
cellular ketone metabolic processGO:0042180800.138
carbohydrate metabolic processGO:00059752070.132
response to oxygen containing compoundGO:19017003690.120
regulation of kinase activityGO:00435493140.113
regulation of ion transportGO:00432691890.104
Mouse
cellular amino acid metabolic processGO:00065201160.102
cation transportGO:00068123310.095
Mouse
single organism carbohydrate metabolic processGO:00447231930.091
regulation of transferase activityGO:00513383550.091
cellular amine metabolic processGO:0044106410.081
regulation of cellular ketone metabolic processGO:0010565500.072
monosaccharide metabolic processGO:0005996740.068
positive regulation of cellular amine metabolic processGO:003324070.064
regulation of cellular amino acid metabolic processGO:000652160.063
regulation of carbohydrate metabolic processGO:0006109540.061
amine metabolic processGO:0009308440.059
cell developmentGO:00484683280.058
Yeast
lipid metabolic processGO:00066293810.056
post embryonic developmentGO:000979120.054
regulation of locomotionGO:00400123290.054
cellular carbohydrate metabolic processGO:0044262840.054
cell projection organizationGO:00300302520.054
regulation of cell differentiationGO:00455953930.053
cellular chemical homeostasisGO:00550821800.050
Mouse
regulation of cellular carbohydrate metabolic processGO:0010675470.049
lipid biosynthetic processGO:00086101770.048
defense responseGO:00069523150.047
positive regulation of protein phosphorylationGO:00019343130.047
positive regulation of transportGO:00510503360.046
transmembrane transportGO:00550853990.045
single organism membrane organizationGO:00448022680.044
positive regulation of cellular component organizationGO:00511303760.044
ion transmembrane transportGO:00342203380.043
metal ion transportGO:00300012720.042
Mouse
regulation of glucose metabolic processGO:0010906280.041
g protein coupled receptor signaling pathwayGO:00071862070.041
negative regulation of catalytic activityGO:00430863350.041
regulation of cellular component movementGO:00512703340.041
regulation of glucokinase activityGO:003313120.040
cellular homeostasisGO:00197251960.039
Mouse
cation transmembrane transportGO:00986552380.038
positive regulation of cellular amino acid metabolic processGO:004576430.038
regulation of protein localizationGO:00328802960.037
female gamete generationGO:000729220.037
response to lipidGO:00339932060.036
regulation of cellular amine metabolic processGO:0033238110.035
membrane organizationGO:00610242920.035
oogenesisGO:004847720.034
negative regulation of cellular component organizationGO:00511292350.034
purine ribonucleoside metabolic processGO:00461284370.034
response to abiotic stimulusGO:00096283360.034
regulation of secretionGO:00510461940.033
regulation of cell motilityGO:20001452990.033
dephosphorylationGO:00163112090.033
regulation of establishment of protein localizationGO:00702012420.032
regulation of anatomical structure morphogenesisGO:00226032860.032
ribonucleoside catabolic processGO:00424544060.032
biological adhesionGO:00226103310.031
neurogenesisGO:00220081690.031
negative regulation of multicellular organismal processGO:00512413170.030
regenerationGO:003109940.030
determination of adult lifespanGO:000834020.030
single organism cellular localizationGO:19025803320.030
nervous system developmentGO:00073992930.030
multicellular organismal agingGO:001025930.030
organic acid transportGO:0015849650.029
protein localization to membraneGO:00726571600.029
calcium ion homeostasisGO:00550741220.028
regulation of transmembrane transportGO:00347621390.028
organonitrogen compound biosynthetic processGO:19015662000.028
protein maturationGO:00516042330.028
regulation of membrane potentialGO:0042391950.028
negative regulation of phosphorus metabolic processGO:00105632670.028
taxisGO:00423301570.028
locomotory behaviorGO:000762610.028
response to nitrogen compoundGO:19016981840.028
cytoplasmic transportGO:00164823790.028
small molecule biosynthetic processGO:00442831570.028
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of metal ion transportGO:00109591200.027
Mouse
cell cell signalingGO:00072671550.027
secretionGO:00469032540.027
negative regulation of phosphate metabolic processGO:00459362670.027
hindbrain developmentGO:003090230.027
generation of neuronsGO:00486991520.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
positive regulation of phosphorylationGO:00423273940.026
reactive oxygen species metabolic processGO:0072593750.026
epithelium developmentGO:00604292270.026
organophosphate catabolic processGO:00464344300.025
cell morphogenesisGO:00009022960.025
regulation of nucleotide metabolic processGO:00061402690.025
nucleotide catabolic processGO:00091664080.025
immune responseGO:00069553070.025
regulation of cellular component biogenesisGO:00440872810.025
glycosyl compound catabolic processGO:19016584130.025
nitrogen compound transportGO:00717051910.025
purine containing compound catabolic processGO:00725234110.024
positive regulation of purine nucleotide metabolic processGO:19005442270.024
negative regulation of apoptotic processGO:00430663160.024
mitotic cell cycleGO:00002783260.024
regulation of reactive oxygen species metabolic processGO:2000377410.024
growthGO:00400072020.024
ribonucleoside triphosphate metabolic processGO:00091994120.023
purine nucleoside catabolic processGO:00061523980.023
response to organonitrogen compoundGO:00102431560.023
cell adhesionGO:00071553250.023
positive regulation of cellular component movementGO:00512721810.023
negative regulation of developmental processGO:00510932470.023
neuromuscular junction developmentGO:000752830.023
regulation of cell cycle processGO:00105642660.023
negative regulation of cell deathGO:00605483450.023
protein processingGO:00164852260.023
negative regulation of transportGO:00510511760.023
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.022
regulation of cell cycleGO:00517263930.022
positive regulation of hydrolase activityGO:00513453310.022
ras protein signal transductionGO:0007265730.022
negative regulation of kinase activityGO:00336731060.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
positive regulation of cell migrationGO:00303351720.022
small gtpase mediated signal transductionGO:0007264780.022
cation homeostasisGO:00550801890.022
organic hydroxy compound biosynthetic processGO:1901617710.022
positive regulation of nucleotide metabolic processGO:00459812300.022
regulation of cell developmentGO:00602841610.022
response to external biotic stimulusGO:00432072610.022
apoptotic signaling pathwayGO:00971902680.022
negative regulation of cell proliferationGO:00082852280.022
nucleoside triphosphate metabolic processGO:00091414220.021
innate immune responseGO:00450871780.021
protein localization to organelleGO:00333652800.021
positive regulation of cell proliferationGO:00082843010.021
negative regulation of programmed cell deathGO:00430693210.021
cellular metal ion homeostasisGO:00068751460.021
response to hormoneGO:00097251750.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
positive regulation of locomotionGO:00400171860.021
regulation of response to external stimulusGO:00321012220.021
inorganic cation transmembrane transportGO:00986621940.021
negative regulation of phosphorylationGO:00423261740.021
regulation of intracellular transportGO:00323861950.020
regulation of cell projection organizationGO:00313441070.020
positive regulation of catabolic processGO:00098963100.020
neurological system processGO:00508771630.020
cardiac muscle cell contractionGO:008600340.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
Yeast
cytosolic calcium ion homeostasisGO:0051480890.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
ribonucleotide catabolic processGO:00092614050.020
nucleoside phosphate catabolic processGO:19012924120.020
potassium ion transmembrane transportGO:0071805600.019
intracellular protein transportGO:00068862700.019
metal ion homeostasisGO:00550651690.019
cardiac muscle contractionGO:0060048340.019
regulation of transporter activityGO:0032409820.019
positive regulation of apoptotic processGO:00430652460.019
protein targetingGO:00066051870.019
segmentationGO:003528240.019
monovalent inorganic cation transportGO:00156721280.019
Mouse
ribonucleoside triphosphate catabolic processGO:00092033910.019
cellular macromolecular complex assemblyGO:00346223240.019
secretion by cellGO:00329402260.019
purine ribonucleotide catabolic processGO:00091544040.019
organophosphate biosynthetic processGO:00904071630.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
cellular macromolecule catabolic processGO:00442653800.019
negative regulation of transferase activityGO:00513481240.019
endomembrane system organizationGO:00102561960.019
action potentialGO:0001508340.019
cell growthGO:00160491600.019
oocyte differentiationGO:000999420.019
regulation of cell growthGO:00015581350.019
positive regulation of kinase activityGO:00336742040.019
purine nucleotide catabolic processGO:00061954050.018
blastoderm segmentationGO:000735020.018
nucleoside triphosphate catabolic processGO:00091433940.018
divalent inorganic cation homeostasisGO:00725071360.018
response to oxygen levelsGO:00704821000.018
ion homeostasisGO:00508012300.018
divalent inorganic cation transportGO:00725111580.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.018
purine ribonucleoside catabolic processGO:00461303980.018
neuron developmentGO:00486661130.018
regulation of proteolysisGO:00301622930.018
carboxylic acid biosynthetic processGO:0046394970.018
cell part morphogenesisGO:00329901370.018
regulation of synaptic plasticityGO:004816730.018
nucleotide biosynthetic processGO:00091651090.018
cellular lipid metabolic processGO:00442553030.018
multi organism cellular processGO:00447641560.018
rhythmic behaviorGO:000762220.018
establishment of protein localization to membraneGO:00901501210.018
signal transduction by phosphorylationGO:00230142970.018
cell projection morphogenesisGO:00488581290.018
nucleoside catabolic processGO:00091644080.018
immune system developmentGO:00025201950.017
cellular cation homeostasisGO:00300031630.017
cellular response to dna damage stimulusGO:00069743790.017
positive regulation of programmed cell deathGO:00430682490.017
system processGO:00030083490.017
response to purine containing compoundGO:0014074400.017
signal releaseGO:0023061700.017
oxidation reduction processGO:00551143960.017
monocarboxylic acid metabolic processGO:00327871850.017
Yeast
negative regulation of protein metabolic processGO:00512483910.017
hormone transportGO:0009914680.017
mitotic cell cycle phase transitionGO:00447721620.017
cellular calcium ion homeostasisGO:00068741170.017
sleepGO:003043120.017
positive regulation of synaptic transmissionGO:005080640.017
chromatin organizationGO:00063253510.017
regulation of protein complex assemblyGO:00432541470.017
gtp catabolic processGO:00061842370.017
regulation of protein transportGO:00512232130.017
regulation of purine nucleotide metabolic processGO:19005422640.016
memoryGO:000761330.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
positive regulation of cell deathGO:00109422630.016
cellular component morphogenesisGO:00329893140.016
vesicle mediated transportGO:00161923710.016
behaviorGO:00076101120.016
nuclear transportGO:00511691790.016
ribose phosphate biosynthetic processGO:0046390820.016
oocyte developmentGO:004859910.016
regulation of cellular response to stressGO:00801352440.016
inorganic ion transmembrane transportGO:00986602310.016
maintenance of locationGO:00512351120.016
positive regulation of cell motilityGO:20001471770.016
positive regulation of cellular catabolic processGO:00313312840.016
microtubule based processGO:00070172100.016
positive regulation of transferase activityGO:00513472270.016
positive regulation of organelle organizationGO:00106381950.016
cytokine productionGO:00018162470.016
reactive oxygen species biosynthetic processGO:190340940.016
actin filament based processGO:00300292240.016
cellular ion homeostasisGO:00068731680.016
hexose metabolic processGO:0019318550.016
response to organophosphorusGO:0046683410.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.015
circadian behaviorGO:004851220.015
steroid metabolic processGO:0008202940.015
response to nutrient levelsGO:0031667810.015
Yeast
cellular protein catabolic processGO:00442572610.015
regulation of cytoskeleton organizationGO:00514931770.015
response to other organismGO:00517072610.015
response to extracellular stimulusGO:0009991850.015
Yeast
negative regulation of intracellular signal transductionGO:19025321830.015
positive regulation of secretionGO:00510471160.015
regulation of protein kinase activityGO:00458592890.015
nucleocytoplasmic transportGO:00069131760.015
lipid homeostasisGO:0055088390.015
cell projection assemblyGO:00300311260.015
compound eye developmentGO:004874910.014
neuron projection developmentGO:00311751060.014
positive regulation of cell differentiationGO:00455972110.014
response to biotic stimulusGO:00096072760.014
response to oxidative stressGO:00069791210.014
neuron differentiationGO:00301821380.014
neurotransmitter secretionGO:000726940.014
regulation of gtp catabolic processGO:00331241800.014
divalent metal ion transportGO:00708381520.014
response to cytokineGO:00340972320.014
response to inorganic substanceGO:00100351270.014
neuroblast proliferationGO:000740540.014
response to decreased oxygen levelsGO:0036293960.014
positive regulation of ion transportGO:0043270870.014
cell morphogenesis involved in differentiationGO:00009041440.014
mitotic cell cycle processGO:19030472860.014
negative regulation of protein maturationGO:19033181420.014
plasma membrane organizationGO:00070091150.014
regulation of neurogenesisGO:0050767820.014
regulation of ion transmembrane transportGO:00347651320.014
calcium ion transportGO:00068161470.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of ion transmembrane transporter activityGO:0032412720.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
metencephalon developmentGO:002203720.014
regulation of growthGO:00400081650.014
negative regulation of cellular amine metabolic processGO:003323930.014
negative regulation of organelle organizationGO:00106391260.014
spermatid differentiationGO:004851540.014
negative regulation of cell differentiationGO:00455961710.014
organic hydroxy compound metabolic processGO:19016151470.014
negative regulation of immune system processGO:00026831360.014
chromatin modificationGO:00165682980.013
adult locomotory behaviorGO:000834410.013
chemotaxisGO:00069351570.013
response to woundingGO:00096111680.013
epithelial cell migrationGO:00106311190.013
regulation of actin filament based processGO:00329701410.013
epidermis morphogenesisGO:004873030.013
generation of precursor metabolites and energyGO:0006091680.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
cellular potassium ion transportGO:0071804600.013
regulation of nervous system developmentGO:0051960880.013
protein oligomerizationGO:00512591730.013
positive regulation of immune responseGO:00507781590.013
histone modificationGO:00165702510.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of transmembrane transporter activityGO:0022898740.013
protein acylationGO:00435431380.013
regulation of secretion by cellGO:19035301770.013
regulation of protein maturationGO:19033171500.013
posttranscriptional regulation of gene expressionGO:00106082130.013
regulation of cell migrationGO:00303342890.013
negative regulation of protein modification processGO:00314002000.013
multicellular organismal signalingGO:0035637340.013
organic acid biosynthetic processGO:0016053970.013
cellular divalent inorganic cation homeostasisGO:00725031280.012
rho protein signal transductionGO:0007266260.012
protein localization to plasma membraneGO:0072659930.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
regulation of multi organism processGO:00439001570.012
cell activationGO:00017752130.012
anterior posterior axis specificationGO:000994820.012
epithelial cell differentiationGO:00308551410.012
organelle assemblyGO:00709251760.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
cellular response to oxygen containing compoundGO:19017012760.012
alpha amino acid metabolic processGO:1901605720.012
guanosine containing compound metabolic processGO:19010682440.012
peptidyl tyrosine modificationGO:00182121700.012
mapk cascadeGO:00001652880.012
cellular amide metabolic processGO:0043603690.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
spermatid developmentGO:000728640.012
protein catabolic processGO:00301633250.012
regulation of defense responseGO:00313471540.012
positive regulation of developmental processGO:00510943140.012
mitochondrion organizationGO:00070051560.012
Human
associative learningGO:000830610.012
cellular response to cytokine stimulusGO:00713451810.012
sensory perceptionGO:00076001030.012
guanosine containing compound catabolic processGO:19010692390.012
actin filament based movementGO:0030048170.012
regulation of purine nucleotide biosynthetic processGO:1900371500.012
cyclic nucleotide biosynthetic processGO:0009190610.012
cell cycle phase transitionGO:00447701730.012
single organismal cell cell adhesionGO:00163371480.012
regulation of apoptotic signaling pathwayGO:20012331750.012
embryonic forelimb morphogenesisGO:003511540.012
response to organic cyclic compoundGO:00140702040.012
regulation of cytoplasmic transportGO:19036491490.012
wound healingGO:00420601150.011
lipid transportGO:0006869900.011
regulation of cell adhesionGO:00301551660.011
response to fungusGO:000962040.011
anion transportGO:00068201610.011
protein localization to nucleusGO:00345041360.011
covalent chromatin modificationGO:00165692540.011
positive regulation of gtp catabolic processGO:00331261660.011
establishment of protein localization to organelleGO:00725941720.011
regulation of gtpase activityGO:00430871800.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
matingGO:000761810.011
astrocyte differentiationGO:004870840.011
regulation of immune responseGO:00507762010.011
sex determinationGO:000753030.011
hormone secretionGO:0046879650.011
sensory perception of painGO:001923340.011
microtubule cytoskeleton organizationGO:00002261760.011
actin cytoskeleton organizationGO:00300362070.011
activation of immune responseGO:00022531140.011
cerebellum developmentGO:002154920.011
negative regulation of growthGO:0045926970.011
protein targeting to nucleusGO:00447441040.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of protein transportGO:00512221350.011
positive regulation of nucleotide catabolic processGO:00308131850.011
lipid localizationGO:00108761060.011
response to hypoxiaGO:0001666960.011
vasculature developmentGO:00019441810.011
tripartite regional subdivisionGO:000735120.011
response to drugGO:0042493810.011
jnk cascadeGO:0007254800.011
organic anion transportGO:00157111030.011
regulation of peptidase activityGO:00525471800.011
regulation of mapk cascadeGO:00434082620.011
cell divisionGO:00513011680.011
carbohydrate derivative biosynthetic processGO:19011372070.011
potassium ion transportGO:0006813620.011
Mouse
protein import into nucleusGO:00066061040.011
regulation of purine nucleotide catabolic processGO:00331212050.011
opioid receptor signaling pathwayGO:003800340.011
regulation of nucleoside metabolic processGO:00091182090.011
cellular protein complex assemblyGO:00436231880.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
negative regulation of synaptic transmissionGO:005080520.011
protein homooligomerizationGO:00512601000.011
sulfur compound metabolic processGO:00067901010.011
regulation of vesicle mediated transportGO:00606271300.011
regulation of dna metabolic processGO:00510521530.011
positive regulation of secretion by cellGO:19035321080.011
ossificationGO:00015031210.011
gtp metabolic processGO:00460392390.011
regulation of meiotic cell cycleGO:005144540.010
regulation of protein stabilityGO:0031647870.010
protein ubiquitinationGO:00165673140.010
proteasomal protein catabolic processGO:00104981760.010
protein stabilizationGO:0050821640.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
behavioral response to ethanolGO:004814920.010
response to axon injuryGO:004867810.010
regulation of nucleotide catabolic processGO:00308112050.010
atp metabolic processGO:00460341760.010
carboxylic acid transportGO:0046942630.010
response to virusGO:00096151260.010
regulation of ras gtpase activityGO:00323181280.010
response to radiationGO:00093141510.010
negative regulation of cell cycleGO:00457861930.010
tissue regenerationGO:004224630.010
positive regulation of cytosolic calcium ion concentrationGO:0007204820.010
ribonucleotide biosynthetic processGO:0009260810.010
ameboidal type cell migrationGO:00016671350.010
positive regulation of odontogenesisGO:004248230.010

GCK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.027
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.023
inherited metabolic disorderDOID:6552420.016
disease of metabolismDOID:00146672950.016
eye and adnexa diseaseDOID:14921500.016
immune system diseaseDOID:29141550.013
disease of cellular proliferationDOID:145661740.013
eye diseaseDOID:56141490.013
cancerDOID:1621670.013
retinal diseaseDOID:56791180.012
organ system cancerDOID:00506861640.012
neurodegenerative diseaseDOID:12891020.012
cardiovascular system diseaseDOID:12871060.012
retinal degenerationDOID:8466890.011
acquired metabolic diseaseDOID:0060158580.004
glucose metabolism diseaseDOID:4194320.004
carbohydrate metabolism diseaseDOID:0050013320.004
diabetes mellitusDOID:9351310.004
type 2 diabetes mellitusDOID:9352280.004
carbohydrate metabolic disorderDOID:2978550.004
maturity onset diabetes of the youngDOID:0050524100.001
hyperinsulinemic hypoglycemiaDOID:1331770.001