Homo sapiens

30 known processes

LGR5

leucine-rich repeat containing G protein-coupled receptor 5

(Aliases: MGC117008,GRP49,GPR67,GPR49,HG38,FEX)

LGR5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.092
cellular ketone metabolic processGO:0042180800.091
system processGO:00030083490.084
Human
regulation of cellular ketone metabolic processGO:0010565500.082
regulation of cellular amine metabolic processGO:0033238110.074
post embryonic developmentGO:000979120.074
amine metabolic processGO:0009308440.070
cellular amine metabolic processGO:0044106410.069
regulation of cell differentiationGO:00455953930.068
regulation of cellular amino acid metabolic processGO:000652160.065
positive regulation of cellular amino acid metabolic processGO:004576430.063
nervous system developmentGO:00073992930.063
epithelium developmentGO:00604292270.062
negative regulation of multicellular organismal processGO:00512413170.061
cell developmentGO:00484683280.060
ion transmembrane transportGO:00342203380.059
circulatory system developmentGO:00723592620.058
positive regulation of cellular amine metabolic processGO:003324070.056
cellular component morphogenesisGO:00329893140.055
segmentationGO:003528240.055
locomotory behaviorGO:000762610.053
regulation of cellular component movementGO:00512703340.052
Human
biological adhesionGO:00226103310.052
transmembrane transportGO:00550853990.052
positive regulation of cellular component organizationGO:00511303760.050
cell morphogenesisGO:00009022960.050
small gtpase mediated signal transductionGO:0007264780.049
cardiovascular system developmentGO:00723582620.049
cellular response to endogenous stimulusGO:00714953360.048
organophosphate catabolic processGO:00464344300.048
purine nucleotide catabolic processGO:00061954050.048
regulation of cell motilityGO:20001452990.047
Human
negative regulation of protein metabolic processGO:00512483910.047
negative regulation of developmental processGO:00510932470.046
ras protein signal transductionGO:0007265730.046
anatomical structure formation involved in morphogenesisGO:00486462840.045
cell projection organizationGO:00300302520.045
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.045
cell adhesionGO:00071553250.045
organ morphogenesisGO:00098871470.045
positive regulation of developmental processGO:00510943140.045
regulation of locomotionGO:00400123290.044
Human
oogenesisGO:004847720.044
nucleoside triphosphate metabolic processGO:00091414220.044
positive regulation of phosphorylationGO:00423273940.044
purine ribonucleotide catabolic processGO:00091544040.044
purine ribonucleoside metabolic processGO:00461284370.044
actin filament based processGO:00300292240.044
glycosyl compound catabolic processGO:19016584130.044
multicellular organismal agingGO:001025930.044
female gamete generationGO:000729220.043
response to oxygen containing compoundGO:19017003690.043
enzyme linked receptor protein signaling pathwayGO:00071673030.043
purine containing compound catabolic processGO:00725234110.043
regulation of anatomical structure morphogenesisGO:00226032860.043
ribonucleoside catabolic processGO:00424544060.042
regulation of cell migrationGO:00303342890.042
Human
lipid metabolic processGO:00066293810.042
purine ribonucleoside triphosphate metabolic processGO:00092054110.041
negative regulation of catalytic activityGO:00430863350.041
positive regulation of cell proliferationGO:00082843010.041
ribonucleoside triphosphate catabolic processGO:00092033910.040
ribonucleotide catabolic processGO:00092614050.040
ribonucleoside triphosphate metabolic processGO:00091994120.040
cation transportGO:00068123310.039
positive regulation of cell differentiationGO:00455972110.039
hindbrain developmentGO:003090230.039
negative regulation of cell deathGO:00605483450.039
purine ribonucleoside triphosphate catabolic processGO:00092073910.039
regulation of cell cycleGO:00517263930.039
purine nucleoside triphosphate metabolic processGO:00091444120.039
negative regulation of phosphorus metabolic processGO:00105632670.038
determination of adult lifespanGO:000834020.038
nucleoside catabolic processGO:00091644080.038
purine nucleoside catabolic processGO:00061523980.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
nucleoside phosphate catabolic processGO:19012924120.037
nucleoside triphosphate catabolic processGO:00091433940.037
negative regulation of phosphate metabolic processGO:00459362670.037
positive regulation of hydrolase activityGO:00513453310.037
membrane organizationGO:00610242920.037
negative regulation of cellular protein metabolic processGO:00322693530.037
morphogenesis of embryonic epitheliumGO:001633140.037
purine ribonucleoside catabolic processGO:00461303980.037
regulation of transferase activityGO:00513383550.036
cellular lipid metabolic processGO:00442553030.036
positive regulation of catabolic processGO:00098963100.036
positive regulation of transportGO:00510503360.036
cytoplasmic transportGO:00164823790.036
response to abiotic stimulusGO:00096283360.036
single organism cellular localizationGO:19025803320.036
nerve developmentGO:002167540.036
negative regulation of cell proliferationGO:00082852280.035
epithelial cell differentiationGO:00308551410.035
signal transduction by phosphorylationGO:00230142970.035
nucleotide catabolic processGO:00091664080.035
anterior posterior axis specificationGO:000994820.034
regulation of nucleotide metabolic processGO:00061402690.034
rho protein signal transductionGO:0007266260.033
chemical homeostasisGO:00488783060.033
negative regulation of programmed cell deathGO:00430693210.033
mapk cascadeGO:00001652880.033
regulation of mapk cascadeGO:00434082620.033
blastoderm segmentationGO:000735020.033
organ formationGO:004864530.033
protein localization to organelleGO:00333652800.033
regulation of protein localizationGO:00328802960.032
single organism membrane organizationGO:00448022680.032
regulation of proteolysisGO:00301622930.032
vesicle mediated transportGO:00161923710.032
cation transmembrane transportGO:00986552380.032
positive regulation of cellular catabolic processGO:00313312840.031
wnt signaling pathwayGO:00160551560.031
immune responseGO:00069553070.030
mitotic cell cycleGO:00002783260.030
regulation of protein kinase activityGO:00458592890.030
cellular response to oxygen containing compoundGO:19017012760.030
generation of neuronsGO:00486991520.030
intracellular protein transportGO:00068862700.030
secretion by cellGO:00329402260.030
regenerationGO:003109940.030
regulation of cellular component biogenesisGO:00440872810.030
canonical wnt signaling pathwayGO:00600701160.030
negative regulation of transportGO:00510511760.029
positive regulation of protein phosphorylationGO:00019343130.029
cell fate determinationGO:000170930.029
negative regulation of apoptotic processGO:00430663160.029
guanosine containing compound metabolic processGO:19010682440.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.028
regulation of nucleoside metabolic processGO:00091182090.028
regulation of purine nucleotide metabolic processGO:19005422640.028
regulation of nucleotide catabolic processGO:00308112050.028
inner ear morphogenesisGO:004247240.028
neuromuscular junction developmentGO:000752830.028
gtp catabolic processGO:00061842370.028
response to organic cyclic compoundGO:00140702040.028
regulation of kinase activityGO:00435493140.028
metal ion transportGO:00300012720.028
regulation of establishment of protein localizationGO:00702012420.028
motor neuron axon guidanceGO:000804520.028
neuron differentiationGO:00301821380.028
peripheral nervous system developmentGO:000742220.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
anion transportGO:00068201610.027
negative regulation of cellular component organizationGO:00511292350.027
cranial nerve developmentGO:002154540.027
regulation of cell cycle processGO:00105642660.027
neurogenesisGO:00220081690.027
blood vessel morphogenesisGO:00485141620.027
vasculature developmentGO:00019441810.027
chemotaxisGO:00069351570.027
cellular response to growth factor stimulusGO:00713631970.027
regulation of intracellular transportGO:00323861950.026
regulation of purine nucleotide catabolic processGO:00331212050.026
mitotic cell cycle processGO:19030472860.026
negative regulation of cell differentiationGO:00455961710.026
regulation of protein transportGO:00512232130.026
adult locomotory behaviorGO:000834410.026
cellular macromolecular complex assemblyGO:00346223240.026
blood vessel developmentGO:00015681720.026
regulation of cell adhesionGO:00301551660.026
blood circulationGO:00080151130.026
nitrogen compound transportGO:00717051910.025
limbic system developmentGO:002176130.025
regulation of cell developmentGO:00602841610.025
positive regulation of cell deathGO:00109422630.025
secretionGO:00469032540.025
regulation of cellular response to stressGO:00801352440.025
defense responseGO:00069523150.025
forelimb morphogenesisGO:003513640.025
guanosine containing compound catabolic processGO:19010692390.025
tissue morphogenesisGO:0048729960.025
inorganic cation transmembrane transportGO:00986621940.025
gtp metabolic processGO:00460392390.024
negative regulation of protein modification processGO:00314002000.024
growthGO:00400072020.024
regulation of wnt signaling pathwayGO:00301111230.024
forebrain generation of neuronsGO:002187230.024
positive regulation of synaptic transmissionGO:005080640.024
protein catabolic processGO:00301633250.024
organonitrogen compound biosynthetic processGO:19015662000.024
cell morphogenesis involved in differentiationGO:00009041440.024
response to growth factorGO:00708482050.024
cellular response to dna damage stimulusGO:00069743790.024
response to biotic stimulusGO:00096072760.024
chromatin organizationGO:00063253510.024
neuron fate commitmentGO:004866320.024
regulation of ion transportGO:00432691890.024
taxisGO:00423301570.024
epithelium migrationGO:00901321190.024
protein processingGO:00164852260.024
protein maturationGO:00516042330.023
regulation of gtp catabolic processGO:00331241800.023
positive regulation of cell motilityGO:20001471770.023
Human
regulation of actin filament based processGO:00329701410.023
memoryGO:000761330.023
regulation of gtpase activityGO:00430871800.023
actin cytoskeleton organizationGO:00300362070.023
positive regulation of nucleotide metabolic processGO:00459812300.023
regulation of secretionGO:00510461940.023
lipid biosynthetic processGO:00086101770.023
cell cell signalingGO:00072671550.023
tube developmentGO:00352951250.023
positive regulation of mapk cascadeGO:00434101900.023
circulatory system processGO:00030131130.023
cardiac muscle cell contractionGO:008600340.023
cellular homeostasisGO:00197251960.023
positive regulation of immune system processGO:00026842830.023
inorganic ion transmembrane transportGO:00986602310.023
neurological system processGO:00508771630.023
Human
carbohydrate derivative biosynthetic processGO:19011372070.023
protein targetingGO:00066051870.023
regulation of cytokine productionGO:00018172320.023
regulation of hormone levelsGO:00108171250.023
negative regulation of phosphorylationGO:00423261740.023
positive regulation of locomotionGO:00400171860.023
Human
embryonic epithelial tube formationGO:000183840.022
regulation of mitotic cell cycleGO:00073461890.022
dephosphorylationGO:00163112090.022
neuron developmentGO:00486661130.022
negative regulation of hydrolase activityGO:00513461820.022
response to lipidGO:00339932060.022
cellular macromolecule catabolic processGO:00442653800.022
ameboidal type cell migrationGO:00016671350.022
response to other organismGO:00517072610.022
regulation of growthGO:00400081650.022
anterior posterior axis specification embryoGO:000859520.022
positive regulation of organelle organizationGO:00106381950.022
single organism cell adhesionGO:00986021790.022
positive regulation of programmed cell deathGO:00430682490.022
regulation of canonical wnt signaling pathwayGO:0060828880.022
negative regulation of cellular amine metabolic processGO:003323930.022
regulation of response to external stimulusGO:00321012220.022
cell part morphogenesisGO:00329901370.022
startle responseGO:000196430.022
chromatin modificationGO:00165682980.022
specification of organ identityGO:001009230.021
positive regulation of nucleotide catabolic processGO:00308131850.021
metencephalon developmentGO:002203720.021
positive regulation of transferase activityGO:00513472270.021
cell growthGO:00160491600.021
regulation of cytoplasmic transportGO:19036491490.021
cytokine productionGO:00018162470.021
nuclear transportGO:00511691790.021
cellular response to organic cyclic compoundGO:00714071270.021
neurotransmitter secretionGO:000726940.021
positive regulation of kinase activityGO:00336742040.021
monocarboxylic acid metabolic processGO:00327871850.021
negative regulation of cell cycleGO:00457861930.021
neuron projection developmentGO:00311751060.021
positive regulation of purine nucleotide catabolic processGO:00331231850.021
ion homeostasisGO:00508012300.021
negative regulation of locomotionGO:00400131180.021
immune system developmentGO:00025201950.021
g protein coupled receptor signaling pathwayGO:00071862070.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
apoptotic signaling pathwayGO:00971902680.021
endomembrane system organizationGO:00102561960.021
somatic stem cell maintenanceGO:003501940.021
tripartite regional subdivisionGO:000735120.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.021
actin filament based movementGO:0030048170.021
regulation of cytoskeleton organizationGO:00514931770.020
positive regulation of nucleoside metabolic processGO:00459791860.020
epithelial cell migrationGO:00106311190.020
nucleocytoplasmic transportGO:00069131760.020
cell projection morphogenesisGO:00488581290.020
response to woundingGO:00096111680.020
embryonic camera type eye developmentGO:003107620.020
positive regulation of protein kinase activityGO:00458601900.020
positive regulation of apoptotic processGO:00430652460.020
negative regulation of cell migrationGO:00303361020.020
establishment of protein localization to organelleGO:00725941720.020
photoreceptor cell differentiationGO:004653020.020
regulation of secretion by cellGO:19035301770.020
hemopoiesisGO:00300971800.020
head developmentGO:00603221080.020
tissue migrationGO:00901301190.020
regulation of protein serine threonine kinase activityGO:00719001790.020
protein localization to membraneGO:00726571600.019
embryonic forelimb morphogenesisGO:003511540.019
hematopoietic or lymphoid organ developmentGO:00485341860.019
skeletal system developmentGO:0001501790.019
posttranscriptional regulation of gene expressionGO:00106082130.019
innate immune responseGO:00450871780.019
protein ubiquitinationGO:00165673140.019
negative regulation of protein phosphorylationGO:00019331400.019
oxidation reduction processGO:00551143960.019
spermatid differentiationGO:004851540.019
carbohydrate metabolic processGO:00059752070.019
oocyte developmentGO:004859910.019
regulation of cell growthGO:00015581350.019
muscle contractionGO:0006936730.019
brain developmentGO:0007420970.019
neuroblast proliferationGO:000740540.019
circadian behaviorGO:004851220.019
protein localization to nucleusGO:00345041360.019
regulation of synaptic plasticityGO:004816730.019
negative regulation of cellular component movementGO:00512711060.019
rhythmic behaviorGO:000762220.019
ossificationGO:00015031210.019
oocyte differentiationGO:000999420.019
microtubule based processGO:00070172100.019
pituitary gland developmentGO:002198320.019
regulation of membrane potentialGO:0042391950.019
response to external biotic stimulusGO:00432072610.018
histone modificationGO:00165702510.018
non canonical wnt signaling pathway via mapk cascadeGO:003803040.018
reactive oxygen species metabolic processGO:0072593750.018
epidermis morphogenesisGO:004873030.018
cellular protein catabolic processGO:00442572610.018
cation homeostasisGO:00550801890.018
regulation of small gtpase mediated signal transductionGO:00510561560.018
regulation of neurotransmitter secretionGO:004692830.018
negative regulation of intracellular signal transductionGO:19025321830.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
regulation of peptidase activityGO:00525471800.018
positive regulation of cellular component movementGO:00512721810.018
Human
somitogenesisGO:000175620.018
actin mediated cell contractionGO:0070252120.018
covalent chromatin modificationGO:00165692540.018
positive regulation of gtp catabolic processGO:00331261660.018
single organism carbohydrate metabolic processGO:00447231930.018
central nervous system developmentGO:00074171230.018
morphogenesis of a polarized epitheliumGO:000173830.018
embryonic viscerocranium morphogenesisGO:004870310.018
regulation of endopeptidase activityGO:00525481700.018
metal ion homeostasisGO:00550651690.018
salivary gland morphogenesisGO:000743540.018
spinal cord developmentGO:002151040.018
response to organonitrogen compoundGO:00102431560.018
epithelial cell proliferationGO:00506731280.018
organic hydroxy compound metabolic processGO:19016151470.018
positive regulation of cytokine productionGO:00018191670.018
regulation of multi organism processGO:00439001570.018
plasma membrane organizationGO:00070091150.017
positive regulation of cellular component biogenesisGO:00440891580.017
positive regulation of cell migrationGO:00303351720.017
Human
regulation of protein catabolic processGO:00421761550.017
organophosphate biosynthetic processGO:00904071630.017
positive regulation of gtpase activityGO:00435471660.017
maintenance of locationGO:00512351120.017
muscle system processGO:0003012810.017
compound eye developmentGO:004874910.017
sex determinationGO:000753030.017
peptidyl tyrosine phosphorylationGO:00181081700.017
response to nitrogen compoundGO:19016981840.017
regulation of epithelial cell proliferationGO:00506781130.017
regulation of immune responseGO:00507762010.017
cerebellum developmentGO:002154920.017
spermatid developmentGO:000728640.017
regulation of ras protein signal transductionGO:00465781550.017
forebrain regionalizationGO:002187130.017
retinal ganglion cell axon guidanceGO:003129020.017
stem cell differentiationGO:0048863930.017
sequestering of calcium ionGO:0051208170.017
regulation of protein maturationGO:19033171500.017
establishment of protein localization to membraneGO:00901501210.017
tissue regenerationGO:004224630.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
cell substrate adhesionGO:00315891320.017
osteoblast differentiationGO:0001649920.017
negative regulation of wnt signaling pathwayGO:0030178690.017
regulation of cell morphogenesisGO:00226041530.017
positive regulation of protein transportGO:00512221350.017
axis elongationGO:000340140.017
divalent metal ion transportGO:00708381520.016
embryo developmentGO:00097901230.016
small molecule biosynthetic processGO:00442831570.016
cardiac muscle contractionGO:0060048340.016
reactive oxygen species biosynthetic processGO:190340940.016
glial cell migrationGO:000834740.016
neural tube formationGO:000184130.016
endodermal cell fate commitmentGO:000171140.016
protein modification by small protein conjugationGO:00324463420.016
divalent inorganic cation transportGO:00725111580.016
protein oligomerizationGO:00512591730.016
calcium ion transportGO:00068161470.016
cellular protein complex assemblyGO:00436231880.016
nucleoside monophosphate metabolic processGO:00091231910.016
regulation of protein processingGO:00706131500.016
cell divisionGO:00513011680.016
regulation of neural precursor cell proliferationGO:200017740.016
positive regulation of ras gtpase activityGO:00323201170.016
cellular response to nitrogen compoundGO:19016991440.016
regulation of intracellular protein transportGO:00331571230.016
organelle assemblyGO:00709251760.016
regulation of ras gtpase activityGO:00323181280.016
angiogenesisGO:00015251470.016
regulation of vesicle mediated transportGO:00606271300.016
forebrain neuron differentiationGO:002187930.016
protein importGO:00170381300.016
neural crest cell developmentGO:001403230.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
hair follicle morphogenesisGO:003106920.016
associative learningGO:000830610.016
cellular response to cytokine stimulusGO:00713451810.016
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.016
regulation of protein complex assemblyGO:00432541470.016
behaviorGO:00076101120.016
negative regulation of growthGO:0045926970.016
regulation of actin cytoskeleton organizationGO:00329561160.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
heart formationGO:006091420.015
single organismal cell cell adhesionGO:00163371480.015
stem cell divisionGO:001714520.015
cell cycle phase transitionGO:00447701730.015
regulation of apoptotic signaling pathwayGO:20012331750.015
response to hormoneGO:00097251750.015
endodermal cell fate specificationGO:000171440.015
mitotic cell cycle phase transitionGO:00447721620.015
reactive nitrogen species metabolic processGO:200105730.015
modification dependent macromolecule catabolic processGO:00436322120.015
striated muscle contractionGO:0006941520.015
response to cytokineGO:00340972320.015
negative regulation of cell motilityGO:20001461040.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
hindlimb morphogenesisGO:003513720.015
cellular response to lipidGO:00713961270.015
sequestering of metal ionGO:0051238240.015
regulation of transmembrane transportGO:00347621390.015
negative regulation of protein processingGO:00109551420.015
microtubule cytoskeleton organizationGO:00002261760.015
positive regulation of hormone biosynthetic processGO:004688640.015
heart developmentGO:0007507950.015
organic anion transportGO:00157111030.015
cellular ion homeostasisGO:00068731680.015
peptidyl tyrosine modificationGO:00182121700.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
embryonic morphogenesisGO:0048598850.015
reproductive processGO:00224141060.015
Human
cellular chemical homeostasisGO:00550821800.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.015
cellular response to organonitrogen compoundGO:00714171240.014
positive regulation of proteolysisGO:00458621420.014
atp metabolic processGO:00460341760.014
negative regulation of cell growthGO:0030308830.014
regulation of homeostatic processGO:00328441210.014
cell activationGO:00017752130.014
primary neural tube formationGO:001402030.014
immune effector processGO:00022521590.014
protein targeting to nucleusGO:00447441040.014
regulation of metal ion transportGO:00109591200.014
tube morphogenesisGO:0035239950.014
negative regulation of canonical wnt signaling pathwayGO:0090090550.014
glycoprotein metabolic processGO:00091001100.014
modification dependent protein catabolic processGO:00199412090.014
response to axon injuryGO:004867810.014
renal system developmentGO:0072001630.014
skin developmentGO:0043588760.014
regulation of dna metabolic processGO:00510521530.014
nuclear importGO:00511701060.014
positive regulation of cell developmentGO:0010720920.014
ubiquitin dependent protein catabolic processGO:00065112060.014
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.014
monovalent inorganic cation transportGO:00156721280.014
regulation of nucleocytoplasmic transportGO:0046822980.014
response to fungusGO:000962040.014
negative regulation of gliogenesisGO:001401430.014
matingGO:000761810.014
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.014
establishment of planar polarityGO:000173630.014
syncytium formation by plasma membrane fusionGO:000076820.014
tube closureGO:006060630.014
regulation of meiotic cell cycleGO:005144540.014
cellular metal ion homeostasisGO:00068751460.014
negative regulation of organelle organizationGO:00106391260.014
morphogenesis of an epitheliumGO:0002009600.014
negative regulation of proteolysisGO:00458611320.014
proteasomal protein catabolic processGO:00104981760.014
receptor metabolic processGO:0043112810.014
regulation of bindingGO:00510981110.014
regulation of axon guidanceGO:190266730.014
endothelial cell migrationGO:0043542860.014
establishment of tissue polarityGO:000716430.014
cell type specific apoptotic processGO:00972851250.014
embryonic eye morphogenesisGO:004804820.014

LGR5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.038
disease of metabolismDOID:00146672950.030
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.028
inherited metabolic disorderDOID:6552420.024
cancerDOID:1621670.021
disease of cellular proliferationDOID:145661740.021
organ system cancerDOID:00506861640.019
central nervous system diseaseDOID:3311860.019
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.017
muscular diseaseDOID:00800001140.017
muscle tissue diseaseDOID:661130.017
eye diseaseDOID:56141490.016
eye and adnexa diseaseDOID:14921500.016
cardiovascular system diseaseDOID:12871060.016