Homo sapiens

26 known processes

PRDX6

peroxiredoxin 6

(Aliases: 1-Cys,NSGPx,AOP2,aiPLA2,PRX,MGC46173,p29,KIAA0106)

PRDX6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidation reduction processGO:00551143960.369
Mouse Rat
cellular response to oxygen radicalGO:007145060.272
cellular response to superoxideGO:007145160.268
cellular homeostasisGO:00197251960.218
multicellular organismal agingGO:001025930.189
response to other organismGO:00517072610.156
determination of adult lifespanGO:000834020.139
response to oxygen containing compoundGO:19017003690.133
Mouse Rat
hydrogen peroxide catabolic processGO:0042744130.127
Rat
nitrogen compound transportGO:00717051910.126
anatomical structure homeostasisGO:00602491000.125
negative regulation of protein metabolic processGO:00512483910.119
response to abiotic stimulusGO:00096283360.113
reactive oxygen species metabolic processGO:0072593750.113
Rat
ras protein signal transductionGO:0007265730.105
protein oxidationGO:001815850.104
negative regulation of cell deathGO:00605483450.102
monocarboxylic acid metabolic processGO:00327871850.101
response to oxidative stressGO:00069791210.098
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.097
negative regulation of cellular protein metabolic processGO:00322693530.096
amide transportGO:0042886760.091
regulation of sequence specific dna binding transcription factor activityGO:00510902110.090
small molecule catabolic processGO:0044282920.090
regulation of kinase activityGO:00435493140.089
response to external biotic stimulusGO:00432072610.087
response to inorganic substanceGO:00100351270.081
Rat
positive regulation of cell deathGO:00109422630.078
immune responseGO:00069553070.078
hydrogen peroxide metabolic processGO:0042743200.077
Rat
negative regulation of proteolysisGO:00458611320.077
negative regulation of apoptotic processGO:00430663160.075
multicellular organismal homeostasisGO:0048871670.075
regulation of cytokine productionGO:00018172320.074
protein maturationGO:00516042330.074
small gtpase mediated signal transductionGO:0007264780.073
cytoplasmic transportGO:00164823790.072
ribonucleotide catabolic processGO:00092614050.072
positive regulation of programmed cell deathGO:00430682490.071
innate immune responseGO:00450871780.071
regulation of membrane potentialGO:0042391950.070
nucleoside triphosphate catabolic processGO:00091433940.070
system processGO:00030083490.070
cellular response to hydrogen peroxideGO:0070301370.069
Rat
intrinsic apoptotic signaling pathwayGO:00971931270.068
negative regulation of phosphate metabolic processGO:00459362670.068
defense responseGO:00069523150.066
glycosyl compound catabolic processGO:19016584130.066
negative regulation of protein maturationGO:19033181420.066
regulation of protein maturationGO:19033171500.063
regulation of cellular amino acid metabolic processGO:000652160.063
ribonucleoside triphosphate catabolic processGO:00092033910.062
secretionGO:00469032540.062
cellular response to oxidative stressGO:0034599850.062
Rat
protein processingGO:00164852260.062
purine containing compound catabolic processGO:00725234110.059
purine nucleotide catabolic processGO:00061954050.059
negative regulation of peptidase activityGO:0010466910.058
negative regulation of phosphorus metabolic processGO:00105632670.057
cellular response to dna damage stimulusGO:00069743790.056
organophosphate catabolic processGO:00464344300.055
cell developmentGO:00484683280.055
peptidyl cysteine modificationGO:001819890.054
positive regulation of cellular amino acid metabolic processGO:004576430.053
response to oxygen radicalGO:000030560.053
negative regulation of endopeptidase activityGO:0010951840.053
cellular lipid metabolic processGO:00442553030.052
carboxylic acid biosynthetic processGO:0046394970.052
lipid biosynthetic processGO:00086101770.052
organic hydroxy compound metabolic processGO:19016151470.052
cellular amide metabolic processGO:0043603690.051
response to uvGO:0009411730.051
secretion by cellGO:00329402260.050
response to radiationGO:00093141510.050
rho protein signal transductionGO:0007266260.050
superoxide metabolic processGO:0006801200.049
response to metal ionGO:0010038840.049
response to reactive oxygen speciesGO:0000302610.048
Mouse Rat
positive regulation of cell proliferationGO:00082843010.048
cellular modified amino acid metabolic processGO:0006575640.048
response to hormoneGO:00097251750.047
epithelium developmentGO:00604292270.047
reactive oxygen species biosynthetic processGO:190340940.047
ion homeostasisGO:00508012300.047
negative regulation of apoptotic signaling pathwayGO:2001234970.047
anatomical structure formation involved in morphogenesisGO:00486462840.046
regulation of protein localizationGO:00328802960.046
response to activityGO:001482300.045
negative regulation of protein processingGO:00109551420.045
inorganic ion transmembrane transportGO:00986602310.045
nucleotide catabolic processGO:00091664080.044
cellular response to endogenous stimulusGO:00714953360.044
primary alcohol metabolic processGO:0034308170.044
cellular amino acid metabolic processGO:00065201160.044
carbohydrate metabolic processGO:00059752070.044
organelle assemblyGO:00709251760.044
negative regulation of programmed cell deathGO:00430693210.043
nucleoside phosphate catabolic processGO:19012924120.043
response to bacteriumGO:00096171440.043
cellular ketone metabolic processGO:0042180800.043
negative regulation of cell proliferationGO:00082852280.042
regulation of gtpase activityGO:00430871800.042
organic acid catabolic processGO:0016054710.041
positive regulation of cytokine productionGO:00018191670.041
positive regulation of transportGO:00510503360.041
regulation of protein kinase activityGO:00458592890.041
cellular response to reactive oxygen speciesGO:0034614500.041
Rat
gtp catabolic processGO:00061842370.040
negative regulation of transportGO:00510511760.040
cytokine productionGO:00018162470.040
agingGO:0007568660.040
response to lipopolysaccharideGO:0032496700.039
response to light stimulusGO:0009416870.039
amine metabolic processGO:0009308440.039
regulation of reactive oxygen species metabolic processGO:2000377410.039
regulation of cellular response to stressGO:00801352440.039
regulation of endopeptidase activityGO:00525481700.038
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.037
response to biotic stimulusGO:00096072760.037
positive regulation of hydrolase activityGO:00513453310.036
regulation of transferase activityGO:00513383550.036
nuclear transportGO:00511691790.036
single organism cellular localizationGO:19025803320.036
negative regulation of hydrolase activityGO:00513461820.036
monocarboxylic acid catabolic processGO:0072329370.036
tissue homeostasisGO:0001894630.036
intracellular protein transportGO:00068862700.036
regulation of intracellular transportGO:00323861950.035
removal of superoxide radicalsGO:001943060.035
myosin filament assemblyGO:003103420.035
regulation of peptidase activityGO:00525471800.034
purine ribonucleoside metabolic processGO:00461284370.034
lipid metabolic processGO:00066293810.034
peptide transportGO:0015833740.034
blood circulationGO:00080151130.034
retina homeostasisGO:0001895420.034
positive regulation of apoptotic processGO:00430652460.034
response to hydrogen peroxideGO:0042542400.033
Rat
regulation of multi organism processGO:00439001570.033
organic acid biosynthetic processGO:0016053970.033
vesicle mediated transportGO:00161923710.033
response to lipidGO:00339932060.033
single organism membrane organizationGO:00448022680.032
regulation of nucleotide metabolic processGO:00061402690.032
regulation of secretionGO:00510461940.032
positive regulation of reactive oxygen species metabolic processGO:2000379240.032
mitochondrion organizationGO:00070051560.032
cellular macromolecular complex assemblyGO:00346223240.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
ribonucleoside triphosphate metabolic processGO:00091994120.032
regulation of mitochondrial membrane potentialGO:0051881230.032
cell cell signalingGO:00072671550.032
regulation of cytoplasmic transportGO:19036491490.031
regenerationGO:003109940.031
oocyte differentiationGO:000999420.031
cellular component morphogenesisGO:00329893140.031
i kappab kinase nf kappab signalingGO:00072491660.031
cation transmembrane transportGO:00986552380.031
negative regulation of catalytic activityGO:00430863350.031
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.030
adult locomotory behaviorGO:000834410.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
tissue regenerationGO:004224630.030
anion transportGO:00068201610.030
membrane organizationGO:00610242920.029
regulation of peptide transportGO:0090087620.029
actin filament based processGO:00300292240.029
lipid catabolic processGO:0016042840.029
gtp metabolic processGO:00460392390.029
regulation of apoptotic signaling pathwayGO:20012331750.029
locomotory behaviorGO:000762610.029
immune effector processGO:00022521590.029
positive regulation of apoptotic signaling pathwayGO:2001235700.028
spermatid differentiationGO:004851540.028
regulation of establishment of protein localizationGO:00702012420.028
peptidyl cysteine oxidationGO:001817110.028
single organism carbohydrate metabolic processGO:00447231930.028
regulation of proteolysisGO:00301622930.028
regulation of i kappab kinase nf kappab signalingGO:00431221620.028
guanosine containing compound metabolic processGO:19010682440.028
response to organic cyclic compoundGO:00140702040.028
segmentationGO:003528240.027
heart contractionGO:0060047620.027
nucleoside catabolic processGO:00091644080.027
negative regulation of transferase activityGO:00513481240.027
post embryonic developmentGO:000979120.027
endomembrane system organizationGO:00102561960.027
negative regulation of multicellular organismal processGO:00512413170.027
negative regulation of kinase activityGO:00336731060.026
regulation of nucleoside metabolic processGO:00091182090.026
regulation of hormone levelsGO:00108171250.026
lipid oxidationGO:0034440330.026
alcohol metabolic processGO:00060661140.026
cellular protein catabolic processGO:00442572610.026
regulation of response to external stimulusGO:00321012220.026
positive regulation of cellular amine metabolic processGO:003324070.026
cellular amine metabolic processGO:0044106410.026
growthGO:00400072020.026
posttranscriptional regulation of gene expressionGO:00106082130.025
regulation of cellular amine metabolic processGO:0033238110.025
ion transmembrane transportGO:00342203380.025
protein localization to organelleGO:00333652800.025
mitochondrial membrane organizationGO:0007006400.024
proteasomal protein catabolic processGO:00104981760.024
regulation of cysteine type endopeptidase activityGO:20001161270.024
purine ribonucleotide catabolic processGO:00091544040.024
regulation of small gtpase mediated signal transductionGO:00510561560.024
inorganic cation transmembrane transportGO:00986621940.024
regulation of cellular ketone metabolic processGO:0010565500.024
regulation of protein processingGO:00706131500.024
female gamete generationGO:000729220.024
striated muscle myosin thick filament assemblyGO:007168820.024
regulation of purine nucleotide catabolic processGO:00331212050.024
negative regulation of multi organism processGO:0043901920.024
neurological system processGO:00508771630.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
rab protein signal transductionGO:003248240.023
purine ribonucleoside catabolic processGO:00461303980.023
dna repairGO:00062811980.023
regulation of ras protein signal transductionGO:00465781550.023
regulation of ras gtpase activityGO:00323181280.023
positive regulation of phosphorylationGO:00423273940.022
extrinsic apoptotic signaling pathwayGO:00971911190.022
positive regulation of protein phosphorylationGO:00019343130.022
cellular aldehyde metabolic processGO:0006081200.022
organic anion transportGO:00157111030.022
heat acclimationGO:001028630.022
ketone catabolic processGO:004218230.022
cellular macromolecule catabolic processGO:00442653800.022
positive regulation of nf kappab transcription factor activityGO:0051092810.022
chemical homeostasisGO:00488783060.022
regulation of response to woundingGO:19030341010.022
mitotic cell cycleGO:00002783260.022
apoptotic signaling pathwayGO:00971902680.022
positive regulation of developmental processGO:00510943140.022
regulation of purine nucleotide metabolic processGO:19005422640.022
alpha amino acid metabolic processGO:1901605720.021
cellular protein complex assemblyGO:00436231880.021
muscle contractionGO:0006936730.021
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.021
regulation of nucleotide catabolic processGO:00308112050.021
dephosphorylationGO:00163112090.021
microtubule cytoskeleton organizationGO:00002261760.021
base excision repairGO:0006284210.021
morphogenesis of embryonic epitheliumGO:001633140.021
protein targetingGO:00066051870.021
apoptotic mitochondrial changesGO:0008637570.021
epithelial cell differentiationGO:00308551410.021
regulation of defense responseGO:00313471540.021
pyruvate transmembrane transportGO:190147510.021
establishment of protein localization to organelleGO:00725941720.021
regulation of protein transportGO:00512232130.021
response to organonitrogen compoundGO:00102431560.020
transmembrane transportGO:00550853990.020
regulation of nucleocytoplasmic transportGO:0046822980.020
response to superoxideGO:000030360.020
nucleoside monophosphate catabolic processGO:00091251590.020
myosin filament organizationGO:003103320.020
nucleoside triphosphate metabolic processGO:00091414220.020
positive regulation of catabolic processGO:00098963100.020
small molecule biosynthetic processGO:00442831570.019
positive regulation of cellular component organizationGO:00511303760.019
single organism reproductive processGO:0044702980.019
actin cytoskeleton organizationGO:00300362070.019
neuromuscular junction developmentGO:000752830.019
cell activationGO:00017752130.019
response to transition metal nanoparticleGO:1990267290.019
negative regulation of immune system processGO:00026831360.019
spermatid developmentGO:000728640.019
cellular component assembly involved in morphogenesisGO:0010927730.019
signal transduction by phosphorylationGO:00230142970.019
cellular response to oxygen containing compoundGO:19017012760.019
Rat
lipid modificationGO:0030258840.018
negative regulation of protein transportGO:0051224750.018
regulation of gtp catabolic processGO:00331241800.018
purine nucleoside catabolic processGO:00061523980.018
cation transportGO:00068123310.018
negative regulation of cysteine type endopeptidase activityGO:2000117480.018
modification dependent macromolecule catabolic processGO:00436322120.018
regulation of transmembrane transportGO:00347621390.018
regulation of bindingGO:00510981110.018
regulation of protein targetingGO:1903533910.018
protein oligomerizationGO:00512591730.018
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of intracellular protein transportGO:00331571230.018
regulation of immune responseGO:00507762010.018
detection of stimulusGO:0051606850.017
cell morphogenesisGO:00009022960.017
immune system developmentGO:00025201950.017
regulation of oxidative stress induced cell deathGO:1903201240.017
anterior posterior axis specificationGO:000994820.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.017
protein catabolic processGO:00301633250.017
mitochondrial transportGO:0006839600.017
positive regulation of nucleotide metabolic processGO:00459812300.017
positive regulation of immune responseGO:00507781590.017
protein acylationGO:00435431380.017
maintenance of locationGO:00512351120.017
response to nitrogen compoundGO:19016981840.017
fatty acid metabolic processGO:00066311150.017
peptide metabolic processGO:0006518510.017
muscle system processGO:0003012810.016
organic hydroxy compound biosynthetic processGO:1901617710.016
positive regulation of superoxide anion generationGO:003293040.016
regulation of proteasomal protein catabolic processGO:0061136870.016
regulation of cell cycleGO:00517263930.016
calcium ion transportGO:00068161470.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
reproductive processGO:00224141060.016
regulation of protein stabilityGO:0031647870.016
regulation of growthGO:00400081650.016
regulation of rho protein signal transductionGO:0035023790.016
endocytosisGO:00068971590.016
protein stabilizationGO:0050821640.016
cation homeostasisGO:00550801890.016
tube developmentGO:00352951250.016
negative regulation of phosphorylationGO:00423261740.016
regulation of cellular component biogenesisGO:00440872810.016
metal ion transportGO:00300012720.016
wound healingGO:00420601150.016
steroid metabolic processGO:0008202940.016
purine nucleoside monophosphate metabolic processGO:00091261860.015
neuron differentiationGO:00301821380.015
response to virusGO:00096151260.015
oogenesisGO:004847720.015
response to woundingGO:00096111680.015
regulation of protein localization to nucleusGO:1900180850.015
regulation of rac gtpase activityGO:003231440.015
protein acetylationGO:00064731160.015
sodium ion transportGO:0006814610.015
cell divisionGO:00513011680.015
oocyte developmentGO:004859910.015
protein ubiquitinationGO:00165673140.015
dna replicationGO:00062601160.015
negative regulation of secretionGO:0051048580.015
positive regulation of immune system processGO:00026842830.015
heart processGO:0003015620.015
nervous system developmentGO:00073992930.015
protein homooligomerizationGO:00512601000.015
response to peptide hormoneGO:0043434610.014
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.014
behaviorGO:00076101120.014
cellular ion homeostasisGO:00068731680.014
protein targeting to nucleusGO:00447441040.014
activation of immune responseGO:00022531140.014
hindbrain developmentGO:003090230.014
regulation of cholesterol metabolic processGO:009018140.014
multi organism cellular processGO:00447641560.014
tripartite regional subdivisionGO:000735120.014
replicative cell agingGO:000130230.014
nucleocytoplasmic transportGO:00069131760.014
matingGO:000761810.014
negative regulation of protein phosphorylationGO:00019331400.014
cell projection morphogenesisGO:00488581290.014
positive regulation of organelle organizationGO:00106381950.014
negative regulation of cell cycleGO:00457861930.014
regulation of cellular response to oxidative stressGO:1900407260.014
response to drugGO:0042493810.014
muscle structure developmentGO:0061061980.014
dna integrity checkpointGO:0031570710.014
cellular amino acid biosynthetic processGO:0008652300.014
regulation of mapk cascadeGO:00434082620.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
cell morphogenesis involved in differentiationGO:00009041440.014
proteolysis involved in cellular protein catabolic processGO:00516032440.013
response to molecule of bacterial originGO:0002237820.013
cellular chemical homeostasisGO:00550821800.013
memoryGO:000761330.013
defense response to other organismGO:00985421290.013
anterior posterior axis specification embryoGO:000859520.013
regulation of response to oxidative stressGO:1902882260.013
positive regulation of synaptic transmissionGO:005080640.013
protein modification by small protein conjugationGO:00324463420.013
interspecies interaction between organismsGO:00444191560.013
anion transmembrane transportGO:0098656760.013
metal ion homeostasisGO:00550651690.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
signal transduction by p53 class mediatorGO:0072331720.013
cell growthGO:00160491600.013
monovalent inorganic cation transportGO:00156721280.013
cellular response to organonitrogen compoundGO:00714171240.013
copulationGO:000762010.013
positive regulation of cellular component movementGO:00512721810.013
tricarboxylic acid metabolic processGO:007235040.013
mapk cascadeGO:00001652880.013
negative regulation of intracellular transportGO:0032387600.012
circulatory system processGO:00030131130.012
protein import into nucleusGO:00066061040.012
regulation of stress activated protein kinase signaling cascadeGO:0070302850.012
positive regulation of secretionGO:00510471160.012
blastoderm segmentationGO:000735020.012
cell substrate adhesionGO:00315891320.012
inseminationGO:000732010.012
regulation of anatomical structure morphogenesisGO:00226032860.012
cellular metal ion homeostasisGO:00068751460.012
regulation of vesicle mediated transportGO:00606271300.012
negative regulation of protein kinase activityGO:0006469980.012
sterol metabolic processGO:0016125280.012
glial cell migrationGO:000834740.012
negative regulation of protein modification processGO:00314002000.012
negative regulation of cell differentiationGO:00455961710.012
regulation of neuron apoptotic processGO:0043523350.012
ubiquitin dependent protein catabolic processGO:00065112060.012
negative regulation of nf kappab transcription factor activityGO:0032088510.012
cellular cation homeostasisGO:00300031630.012
actomyosin structure organizationGO:0031032590.012
cell type specific apoptotic processGO:00972851250.012
catecholamine biosynthetic processGO:004242340.012
response to acid chemicalGO:0001101660.011
cholesterol metabolic processGO:0008203280.011
mitotic cell cycle processGO:19030472860.011
cellular response to organic cyclic compoundGO:00714071270.011
cell death in response to oxidative stressGO:0036473290.011
fatty acid oxidationGO:0019395310.011
actin mediated cell contractionGO:0070252120.011
response to growth factorGO:00708482050.011
cellular modified amino acid biosynthetic processGO:0042398150.011
striated muscle contractionGO:0006941520.011
angiogenesisGO:00015251470.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
protein localization to membraneGO:00726571600.011
hormone secretionGO:0046879650.011
cell cycle checkpointGO:00000751170.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of nucleoside metabolic processGO:00459791860.011
tissue morphogenesisGO:0048729960.011
protein deubiquitinationGO:0016579790.011
multicellular organismal response to stressGO:003355510.011
response to mercury ionGO:004668940.011
response to salt stressGO:000965130.011
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.011
monocarboxylic acid biosynthetic processGO:0072330670.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
striated muscle cell differentiationGO:0051146430.011
internal protein amino acid acetylationGO:00064751010.011
stress activated protein kinase signaling cascadeGO:0031098940.011
microtubule based processGO:00070172100.011
metencephalon developmentGO:002203720.011
rna interferenceGO:001624640.011
microtubule organizing center organizationGO:0031023620.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.011
organ morphogenesisGO:00098871470.011
divalent inorganic cation transportGO:00725111580.011
regulation of innate immune responseGO:0045088970.011
hemopoiesisGO:00300971800.011
negative regulation of response to external stimulusGO:0032102830.011
regulation of neural precursor cell proliferationGO:200017740.011
phototransductionGO:000760230.011
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.010
response to hyperoxiaGO:005509340.010
taxisGO:00423301570.010
positive regulation of secretion by cellGO:19035321080.010
single organism nuclear importGO:19025931040.010
receptor mediated endocytosisGO:0006898840.010
syncytium formation by plasma membrane fusionGO:000076820.010
positive regulation of nucleotide catabolic processGO:00308131850.010
hormone transportGO:0009914680.010
myoblast fusionGO:000752010.010
inner ear morphogenesisGO:004247240.010
mitochondrion degradationGO:000042280.010
regulation of cell cycle processGO:00105642660.010
positive regulation of cellular catabolic processGO:00313312840.010
generation of neuronsGO:00486991520.010
cardiovascular system developmentGO:00723582620.010
sensory perception of painGO:001923340.010
multi organism reproductive processGO:0044703540.010
carboxylic acid catabolic processGO:0046395710.010
regulation of rab gtpase activityGO:0032313390.010
regulation of dephosphorylationGO:0035303960.010
embryo developmentGO:00097901230.010
ribonucleoside catabolic processGO:00424544060.010
negative regulation of developmental processGO:00510932470.010
activation of cysteine type endopeptidase activityGO:0097202570.010

PRDX6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.090
cancerDOID:1621670.045
disease of cellular proliferationDOID:145661740.045
central nervous system diseaseDOID:3311860.039
nervous system diseaseDOID:8634310.039
organ system cancerDOID:00506861640.028
inherited metabolic disorderDOID:6552420.022
hyperinsulinemic hypoglycemiaDOID:1331770.022
carbohydrate metabolic disorderDOID:2978550.022
neurodegenerative diseaseDOID:12891020.022
endocrine gland cancerDOID:170260.016
musculoskeletal system diseaseDOID:172230.016
urinary system diseaseDOID:18400.013